Kelsey McNew

Journal article Journal of surgical education · November 2022 ObjectivePelvic examinations under anesthesia (EUAs) are routine components of gynecologic surgery and often used to educate students about female pelvic anatomy. This multi-institutional survey study aims to describe students' experiences with co ... Full text Cite

Vascular alterations impede fragile tolerance to pregnancy in type 1 diabetes.

Journal article F&S science · May 2022 ObjectiveTo determine the impact of autoimmunity in the absence of glycemic alterations on pregnancy in type 1 diabetes (T1D).DesignBecause nonobese diabetic (NOD) mice experience autoimmunity before the onset of hyperglycemia, we studied ... Full text Open Access Cite

Group B streptococcal infection of the genitourinary tract in pregnant and non-pregnant patients with diabetes mellitus: An immunocompromised host or something more?

Journal article American journal of reproductive immunology (New York, N.Y. : 1989) · December 2021 Group B Streptococcus (GBS), also known as Streptococcus agalactiae is a Gram-positive bacterium commonly encountered as part of the microbiota within the human gastrointestinal tract. A common cause of infections during pregnancy, GBS is responsible for i ... Full text Cite

Metabolic preconditioning in CD4+ T cells restores inducible immune tolerance in lupus-prone mice.

Journal article JCI insight · October 2021 Autoimmune disease has presented an insurmountable barrier to restoration of durable immune tolerance. Previous studies indicate that chronic therapy with metabolic inhibitors can reduce autoimmune inflammation, but it remains unknown whether acute metabol ... Full text Cite

Natural aversive learning in Tetramorium ants reveals ability to form a generalizable memory of predators' pit traps.

Journal article Behavioural processes · June 2017 Many species of ants fall prey to pit-digging larval antlions (Myrmeleon spp.), extremely sedentary predators that wait, nearly motionless at the bottom of their pit traps, for prey to stumble inside. Previous research, both in the field and laboratory, ha ... Full text Cite

MEK and TAK1 Regulate Apoptosis in Colon Cancer Cells with KRAS-Dependent Activation of Proinflammatory Signaling.

Journal article Molecular cancer research : MCR · December 2016 MEK inhibitors have limited efficacy in treating RAS-RAF-MEK pathway-dependent cancers due to feedback pathway compensation and dose-limiting toxicities. Combining MEK inhibitors with other targeted agents may enhance efficacy. Here, codependencies of MEK, ... Full text Cite