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Kouros Owzar

Professor of Biostatistics & Bioinformatics
Biostatistics & Bioinformatics, Division of Integrative Genomics
Duke Box 2717, Durham, NC 27710
2424 Erwin Road, 7078 Hock Plaza, Durham, NC 27705

Overview


cancer pharmacogenomics
drug induced neuropathy, neutropenia and hypertension
statistical genetics
statistical methods for high-dimensional data
copulas
survival analysis
statistical computing

Current Appointments & Affiliations


Professor of Biostatistics & Bioinformatics · 2021 - Present Biostatistics & Bioinformatics, Division of Integrative Genomics, Biostatistics & Bioinformatics
Member of the Duke Cancer Institute · 2013 - Present Duke Cancer Institute, Institutes and Centers

Recent Publications


A comprehensive, multi-center, immunogenomic analysis of melanoma brain metastases.

Journal Article Acta Neuropathol Commun · June 2, 2025 BACKGROUND: Melanoma brain metastases (MBM) have a unique molecular profile compared to extracranial metastases (ECM). Description of the biological features and clinical outcomes of MBM will facilitate the design of rational therapies. METHODS: We examine ... Full text Link to item Cite

Genomic and immune profiling of breast cancer brain metastases.

Journal Article Acta Neuropathol Commun · May 12, 2025 BACKGROUND: Brain metastases (BrM) arising from breast cancer (BC) are an increasing consequence of advanced disease, with up to half of patients with metastatic HER2 + or triple negative BC experiencing central nervous system (CNS) recurrence. The genomic ... Full text Link to item Cite

Genomic alterations are associated with response to aromatase inhibitor therapy for ER-positive postmenopausal ductal carcinoma in situ: (CALGB 40903, Alliance).

Journal Article Breast Cancer Res · February 20, 2025 PURPOSE: CALGB 40903 (Alliance) was a phase II single arm multicenter trial conducted in postmenopausal patients diagnosed with estrogen-receptor (ER) positive breast ductal carcinoma in situ (DCIS) without invasion. Patients were treated with the aromatas ... Full text Link to item Cite
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Recent Grants


Disparate Survival, Disparate Workforce: An Integrated Approach to Improving Head and Neck Cancer Outcomes and Diversity in the Oncology Workforce

ResearchBioinformatics Specialist · Awarded by National Institute of Dental and Craniofacial Research · 2024 - 2029

Quantitative Methods for HIV/AIDS Research

Inst. Training Prgm or CMESteering Committee Member · Awarded by National Institute of Allergy and Infectious Diseases · 2018 - 2028

Single Cell and Spatial Analysis of Lethal Breast Cancers

ResearchCo Investigator · Awarded by Department of Defense · 2024 - 2028

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Education, Training & Certifications


University of North Carolina, Chapel Hill · 2002 Ph.D.