Overview
cancer pharmacogenomics
drug induced neuropathy, neutropenia and hypertension
statistical genetics
statistical methods for high-dimensional data
copulas
survival analysis
statistical computing
drug induced neuropathy, neutropenia and hypertension
statistical genetics
statistical methods for high-dimensional data
copulas
survival analysis
statistical computing
Current Appointments & Affiliations
Professor of Biostatistics & Bioinformatics
·
2021 - Present
Biostatistics & Bioinformatics, Division of Integrative Genomics,
Biostatistics & Bioinformatics
Director, DCI Bioinformatics
·
2013 - Present
Biostatistics & Bioinformatics, Division of Biostatistics,
Biostatistics & Bioinformatics
Member of the Duke Cancer Institute
·
2013 - Present
Duke Cancer Institute,
Institutes and Centers
Recent Publications
Genomic alterations are associated with response to aromatase inhibitor therapy for ER-positive postmenopausal ductal carcinoma in situ: (CALGB 40903, Alliance).
Journal Article Breast Cancer Res · February 20, 2025 PURPOSE: CALGB 40903 (Alliance) was a phase II single arm multicenter trial conducted in postmenopausal patients diagnosed with estrogen-receptor (ER) positive breast ductal carcinoma in situ (DCIS) without invasion. Patients were treated with the aromatas ... Full text Link to item CiteCharacterization of the Biological Variability of the Angiome Biomarkers over Time in Healthy Participants.
Journal Article Cancer Epidemiol Biomarkers Prev · January 9, 2025 BACKGROUND: Biomarker analyses are an integral part of cancer research. Despite the intense efforts to identify and characterize biomarkers in patients with cancer, little is known regarding the natural variation of biomarkers in healthy populations. Here ... Full text Link to item CiteTEMPTED: time-informed dimensionality reduction for longitudinal microbiome studies.
Journal Article Genome Biol · December 19, 2024 Longitudinal studies are crucial for understanding complex microbiome dynamics and their link to health. We introduce TEMPoral TEnsor Decomposition (TEMPTED), a time-informed dimensionality reduction method for high-dimensional longitudinal data that treat ... Full text Link to item CiteRecent Grants
Disparate Survival, Disparate Workforce: An Integrated Approach to Improving Head and Neck Cancer Outcomes and Diversity in the Oncology Workforce
ResearchBioinformatics Specialist · Awarded by National Institute of Dental and Craniofacial Research · 2024 - 2029Quantitative Methods for HIV/AIDS Research
Inst. Training Prgm or CMESteering Committee Member · Awarded by National Institute of Allergy and Infectious Diseases · 2018 - 2028Single Cell and Spatial Analysis of Lethal Breast Cancers
ResearchCo Investigator · Awarded by Department of Defense · 2024 - 2028View All Grants
Education, Training & Certifications
University of North Carolina, Chapel Hill ·
2002
Ph.D.