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Kris Mahadeo

Professor of Pediatrics
Pediatrics, Transplant and Cellular Therapy
Pediatric Transplant and Cellular Therapy, 2400 Pratt Street, Durham, NC 27705

Scholarly Works - Book sections


Miscellaneous Complications of Hematopoietic Cellular Transplantation

Book section · January 1, 2023 Advancements in hematopoietic cell transplantation (HCT) have been associated with expanding indications and eligibility, alternative donor options, and improvement in overall survival. Yet, HCT for hematologic malignancies are still associated with the po ... Full text Cite

Care of the Critically Ill Pediatric Hematopoietic Cell Transplant Patient

Book section · January 1, 2021 Although potentially curative therapy, hematopoietic cell transplantation (HCT) is fraught with many unique and life-threatening complications. Pulmonary complications, both infectious and noninfectious, are common and a significant source of nonrelapse mo ... Full text Cite

Special Considerations for ICU Management of Patients Receiving CAR Therapy

Book section · January 1, 2020 Chimeric antigen receptor (CAR) T-cells belong to the class of immune effector cell (IEC) therapies, which have been associated with striking clinical outcomes, particularly among patients with relapsed/refractory hematologic malignancies. Yet, they have a ... Full text Cite

Chimeric antigen receptor (CAR) t-cell therapy in the pediatric critical care

Book section · October 12, 2019 In 2017, the US Food and Drug Administration (FDA) approved a form of cancer immunotherapy, specifically, a chimeric antigen receptor (CAR), for the treatment of pediatric and young adult patients with refractory CD19-positive B-cell precursor acute lympho ... Full text Cite

Hematopoietic Stem Cell Transplant and Cellular Therapy

Book section · January 1, 2019 Hematopoietic cell transplantation (HCT) and cellular therapy (CT) are potentially lifesaving treatments for children with malignant and nonmalignant diseases. Advancements in care have led to expanding patient eligibility, with overall reduced morbidity a ... Full text Cite