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Jeffrey Adam Kuller

Professor of Obstetrics and Gynecology
Obstetrics and Gynecology, Maternal Fetal Medicine
Box 3967 Med Ctr, 2608 Erwin Road; Suite 200, Durham, NC 27705
11001 Durant Road, Suite 114, Raleigh, NC 27614

Featured Works


First trimester screening.

Journal article Gynecol Obstet Invest · 2005 Featured Publication Screening for aneuploidy has traditionally been reserved for women of advanced maternal age. More recent advances in serum screening and ultrasound technology have allowed women of all ages to be offered screening in the second and even first trimester. Th ... Full text Link to item Cite

Omphalocele: clinical outcomes in cases with normal karyotypes.

Journal article Am J Obstet Gynecol · January 2004 Featured Publication OBJECTIVE: This study was undertaken to examine neonatal outcomes in karyotypically normal cases of omphalocele with respect to mode of delivery, presence of associated anomalies, presence of extracorporeal liver, and method of abdominal wall closure. STUD ... Full text Link to item Cite

Gastroschisis: the effect of labor and ruptured membranes on neonatal outcome.

Journal article Am J Obstet Gynecol · December 2003 Featured Publication OBJECTIVES: The purpose of this study was to examine the relationship between labor and ruptured membranes on the neonatal outcome of infants with gastroschisis. STUDY DESIGN: We reviewed the outcomes of 60 neonates who were prenatally diagnosed with gastr ... Full text Link to item Cite

Thrombophilias and recurrent miscarriage.

Journal article Obstet Gynecol Surv · October 2002 Featured Publication Inherited and acquired thrombophilias have been associated with recurrent pregnancy loss. Over recent years our ability to detect protein and genetic abnormalities responsible for thrombotic tendency has improved. We are now left with the task of decipheri ... Full text Link to item Cite

Hyperemesis gravidarum complicated by Wernicke's encephalopathy.

Journal article Obstet Gynecol · May 2002 Featured Publication BACKGROUND: Wernicke's encephalopathy is usually associated with alcohol abuse, but can also occur with hyperemesis gravidarum. The effect of delay in thiamine replacement on fetal outcomes is unknown. We present a case of this complication. CASE: A primip ... Full text Link to item Cite

Disposition of sperm donors with resultant abnormal pregnancies.

Journal article Hum Reprod · August 2001 Featured Publication We wished to determine how clinicians manage sperm donors whose offspring have chromosomal or structural abnormalities. A directed, multiple-choice survey was given to reproductive endocrinologists and obstetrical geneticists to assess management of sperm ... Full text Link to item Cite

Pregnancy in transplant recipients.

Journal article Obstet Gynecol Surv · May 2001 Featured Publication A growing number of transplant recipients are women of reproductive age or children who will reach reproductive age. Thus, menstrual function and pregnancy increasingly are important issues because fertility is restored to women who were previously unable ... Full text Link to item Cite

Renal biopsy and pregnancy.

Journal article Am J Obstet Gynecol · May 2001 Featured Publication OBJECTIVE: Our aim was to review our experience with renal biopsy in pregnancy. STUDY DESIGN: We reviewed 18 renal biopsies performed during pregnancy or in the immediate postpartum period at the University of North Carolina. Indications, histopathologic f ... Full text Link to item Cite

Preeclampsia into eclampsia: toward a new paradigm.

Journal article Am J Obstet Gynecol · June 2000 Featured Publication OBJECTIVE: This study was undertaken to characterize aspects of the natural history of eclampsia. STUDY DESIGN: A retrospective analysis was performed on the records of patients with eclampsia who were delivered at two tertiary care hospitals. RESULTS: Fif ... Full text Link to item Cite

Urinary incontinence in pregnancy and the puerperium: a prospective study.

Journal article Am J Obstet Gynecol · August 1999 Featured Publication OBJECTIVE: Pregnancy and childbirth are commonly thought to be associated with the development of urinary incontinence and lower urinary tract symptoms. The purpose of this study was to assess the relationship, if any, between pregnancy and the development ... Full text Link to item Cite

Management of cervical cerclage after preterm premature rupture of membranes.

Journal article Obstet Gynecol Surv · June 1999 Featured Publication The optimal management of preterm premature rupture of membranes (PPROM) in a patient with a cerclage is controversial. The issues are whether the latency period between rupture of membranes and delivery is decreased if the cerclage is removed and whether ... Full text Link to item Cite

Cystic fibrosis and the National Institutes of Health consensus statement: are obstetrician-gynecologists ready to comply?

Journal article Obstet Gynecol · April 1999 Featured Publication OBJECTIVE: To determine if obstetrician-gynecologists are ready to comply with the April 1997 National Institutes of Health (NIH) consensus statement regarding carrier screening for cystic fibrosis. METHODS: A multiple-choice questionnaire was mailed to al ... Full text Link to item Cite

Central hemodynamic effects of an oxytocin receptor antagonist (atosiban) in the isolated, perfused rat heart.

Journal article J Soc Gynecol Investig · 1999 Featured Publication OBJECTIVE: Atosiban is a selective oxytocin receptor antagonist capable of inhibiting oxytocin-induced contractility of the uterus. Trials of this agent in intact animals and women as a tocolytic agent for preterm labor have shown atosiban to be devoid of ... Link to item Cite

Prenatal diagnosis of mosaic trisomy 13: a case report.

Journal article Prenat Diagn · September 1998 Featured Publication While the clinical features associated with full trisomy 13 have been well characterized, the clinical outcome associated with mosaic trisomy 13 is much less clear. The medical literature reports a broad range of possible clinical outcomes from severe ment ... Full text Link to item Cite

Perinatal outcomes in women with systemic lupus erythematosus.

Journal article J Perinatol · 1998 Featured Publication OBJECTIVE: Pregnancies of women with systemic lupus erythematosus (SLE) were studied to assess the effects interaction of this disease and pregnancy. STUDY DESIGN: Charts of pregnant women with a discharge diagnosis of lupus were reviewed. Inclusion criter ... Link to item Cite

Clinical Crossroads: a 36-year-old woman recuperating from stroke.

Journal article JAMA · October 1, 1997 Featured Publication Link to item Cite