Journal articleAm J Perinatol · July 9, 2026
OBJECTIVE: Antepartum bleeding is a common complication of placenta previa and contributes to maternal and neonatal morbidity; however, limited data describe bleeding patterns and their clinical course. We sought to identify predictors of antepartum bleedi ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · July 1, 2026
IMPORTANCE: Preterm premature rupture of membranes (PPROM) presents significant challenges in obstetric care, particularly due to its association with both maternal and neonatal morbidity. Management becomes even more complex when PPROM occurs in the conte ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · June 1, 2026
IMPORTANCE: The prevalence of atrial fibrillation (AF) and atrial flutter (AFL) among pregnant patients has increased over time, with AF now being the most common sustained cardiac arrhythmia in pregnancy. Management of AF/AFL in pregnancy presents unique ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · May 1, 2026
IMPORTANCE: Male sexual dysfunction has been well described in scientific literature; however, female sexual dysfunction is an area of research that remains vastly overlooked. OBJECTIVE: Female sexual dysfunction represents 4 separate diagnoses according t ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · April 1, 2026
IMPORTANCE: Trauma and childbirth-related posttraumatic stress disorder (c-PTSD) are underrecognized possible consequences of birth and obstetric care that may affect maternal well-being, parent-infant bonding, and future reproductive decisions. Despite a ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · March 1, 2026
IMPORTANCE: Penicillin allergies are commonly reported in pregnancy, yet patients are rarely truly allergic. Identification of pregnant patients who would benefit from penicillin allergy testing is an important public health initiative to reduce alternativ ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · February 1, 2026
IMPORTANCE: Furcate umbilical cord insertion is a rare anomaly in which the umbilical vessels separate and lose Wharton jelly before placental insertion. This condition increases the risk of complications such as vessel avulsion and intrauterine fetal demi ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · January 1, 2026
IMPORTANCE: Physiological changes in pregnancy pose unique challenges for cirrhosis and portal hypertension, particularly during the third trimester and intrapartum setting. Pregnancy may increase the risk of worsening of esophageal varices and life-threat ...
Full textLink to itemCite
Journal articleMedicine United States · January 1, 2026
Learning Objectives: After participating in this continuing professional development activity, the provider should be better able to: ...
Full textCite
Journal articleObstet Gynecol Surv · November 1, 2025
IMPORTANCE: Breast cancer is one of the most common malignancies among women globally, with significant implications for reproductive health, including the use of contraception. The intersection of breast cancer and contraception presents unique challenges ...
Full textLink to itemCite
Journal articleAm J Perinatol · October 2025
Anemia is observed in 30% of pregnancies with pyelonephritis, yet little is known about the underlying etiology. Erythropoietin (EPO) is renally produced in response to hypoxic and inflammatory conditions. Changes in serum EPO have been demonstrated in inf ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · September 2025
IMPORTANCE: The United States continues to have one of the highest adolescent pregnancy rates compared with other high-income countries. Adolescents and their children have an increased risk of adverse health effects. These disparities demonstrate the need ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · July 2025
IMPORTANCE: Influenza presents as respiratory illnesses that range in severity and can lead to adverse maternal health outcomes and pregnancy complications, particularly in pregnant individuals who are considered high-risk for severe disease. OBJECTIVE: To ...
Full textLink to itemCite
Journal articleBrain · June 3, 2025
Malformations of cortical development (MCDs) are a heterogeneous family of congenital brain malformations that originate from disturbed development of the cerebral cortex. MCDs can arise from primary genetic disorders that lead to dysfunction of the molecu ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · June 2025
IMPORTANCE: Oropouche is an emerging virus that has become a growing cause for concern after reports of vertical transmission and detrimental effects on the developing fetus. Oropouche is an arbovirus, meaning it is transmitted by arthropods, which include ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · May 2025
IMPORTANCE: Hemolytic disease of the fetus and newborn (HDFN) is caused by maternal alloantibodies to fetal red blood cells and is associated with significant fetal and neonatal morbidity and mortality. Rhesus D antigen (RhD)-mediated HDFN is the only prev ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · January 2025
IMPORTANCE: To decrease associated infectious and thrombotic morbidity, it is important to understand the indications and risks of peripherally inserted central catheters (PICCs) and other vascular access means in pregnancy. OBJECTIVES: The objectives are ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · December 2024
IMPORTANCE: With a strong association between hepatic adenomas and estrogen established, understanding the risks, evaluation, and perinatal management of hepatic adenomas is necessary for obstetric clinicians. OBJECTIVE: The aim of this study is to review ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · November 2024
IMPORTANCE: Fetal macrosomia (FM) is common in clinical practice and carries increased risk of adverse maternal and neonatal health outcomes. Maternal diabetes mellitus (DM) is a well-known cause of macrosomia with significant research and guidelines focus ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · October 2024
IMPORTANCE: Though the incidence of familial Mediterranean fever (FMF) in pregnancy is rare, understanding the etiology and symptomatology of FMF is essential for obstetric treatment of patients with FMF. OBJECTIVE: Familial Mediterranean fever is a heredi ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · October 2024
IMPORTANCE: Cannabis is commonly used by pregnant patients for alleviation of pregnancy-associated symptoms. Multiple national medical associations have recommended against prenatal cannabis use, yet misinformation regarding its safety and efficacy remains ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · September 2024
IMPORTANCE: The latent phase of labor poses a challenge for pregnant patients due to the limited options available for pain relief and management. Therapeutic rest, an intervention involving medication administration during this phase, has shown promise in ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · September 2024
IMPORTANCE: With advances in prenatal cell-free DNA (cfDNA) technology, the information available with cfDNA continues to expand beyond the common fetal aneuploidies such as trisomies 21, 18, and 13. Due to the admixture of maternal and fetal/placental DNA ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · August 2024
IMPORTANCE: The identification of the cavum septum pellucidum (CSP) is an integral part of the routine second trimester fetal anatomy scan. The absence or nonvisualization of the CSP has significant clinical implications and requires further evaluation and ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · June 2024
IMPORTANCE: Diabetes mellitus is one of the most common complications in pregnancy with adverse maternal and neonatal risks proportional to the degree of suboptimal glycemic control, which is not well defined. Literature guiding providers in identifying an ...
Full textLink to itemCite
Journal articleAm J Obstet Gynecol · May 2024
Guidelines for the management of first-trimester spontaneous and induced abortion vary in terms of rhesus factor D (RhD) testing and RhD immune globulin (RhIg) administration. These existing guidelines are based on limited data that do not convincingly dem ...
Full textLink to itemCite
Journal articleObstetrical & gynecological survey · May 2024
ImportanceAlthough the risk of parvovirus B19 infection during pregnancy and subsequent risk of adverse fetal outcome are low, understanding management practices is essential for proper treatment of fetuses with nonimmune hydrops fetalis. In addit ...
Full textCite
Journal articleObstetrical & gynecological survey · March 2024
ImportanceIn pregnancy, cell-free DNA (cfDNA) represents short fragments of placental DNA released into the maternal blood stream through natural cell death. Noninvasive prenatal screening with cfDNA is commonly used in pregnancy to screen for com ...
Full textCite
Journal articleAm J Obstet Gynecol · February 2024
Respiratory syncytial virus is a leading cause of lower respiratory tract illness globally in children aged <5 years. Each year, approximately 58,000 hospitalizations in the United States are attributed to respiratory syncytial virus. Infants aged ≤6 month ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · February 2024
IMPORTANCE: Luteal phase defects (LPDs), or an insufficiency of progesterone production during the luteal phase of the menstrual cycle, have been identified as a potential cause of recurrent pregnancy loss (RPL), but its exact contribution to RPL is not we ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · January 2024
IMPORTANCE: Induction of labor (IOL) is a common obstetric intervention. Augmentation of labor and active management of the second stage is frequently required in obstetric practice. However, techniques around labor and induction management vary widely. Ev ...
Full textLink to itemCite
Journal articleClin Obstet Gynecol · December 1, 2023
All patients with twin pregnancy should have first trimester ultrasound and be offered screening for chromosomal aneuploidy as well as diagnostic testing. Screening for aneuploidy in twins presents unique challenges compared with singletons. Cell-free DNA ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · October 2023
IMPORTANCE: Obstetrics and gynecology (OB/GYN) accounts for at least half of all open abdominal surgeries performed. Rates of surgical wound complications after open procedures in OB/GYN range from 5% to 35%. Therefore, optimizing management of surgical wo ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · October 2023
The use of tobacco and nicotine products during pregnancy is known to increase the risk of adverse effects on the fetus. Increased education and research have resulted in greater rates of smoking cessation during pregnancy, with a decline from 13.2% of pre ...
Full textLink to itemCite
Journal articleClin Obstet Gynecol · September 1, 2023
Twin pregnancy presents unique considerations for aneuploidy screening. Pre-test counseling regarding benefits, alternatives, and options for aneuploidy screening should be provided to all patients carrying twin pregnancy. This article aims to review the o ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · August 2023
IMPORTANCE: CenteringPregnancy (CP) is a model for group prenatal care associated with improved perinatal outcomes for preterm birth and low birthweight, increased rates of breastfeeding, and higher rates of patient and clinician satisfaction. OBJECTIVE: T ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · August 2023
IMPORTANCE: Genetic carrier screening is performed to identify carriers of rare genetic diseases. Identification of carriers allows patients to make informed reproductive health choices and can decrease the incidence of genetic disorders with serious medic ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · July 2023
IMPORTANCE: Autoimmune and rheumatologic conditions can lead to multiple adverse maternal, obstetric, and neonatal outcomes, especially if they flare during pregnancy. Although many medications to control these conditions exist, concerns regarding their sa ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · July 2023
IMPORTANCE: Multiple postpartum scenarios require uterine exploration or instrumentation. These may introduce bacteria into the uterus, increasing the risk of endometritis. Data on the use of antibiotics in these scenarios is limited, resulting in few guid ...
Full textLink to itemCite
Journal articleAJP Rep · July 2023
Adnexal masses in the third trimester of pregnancy may obstruct the pelvic outlet precluding labor induction and vaginal delivery. Expectant versus surgical management of adnexal cysts in pregnancy must carefully weigh maternal-fetal benefits and risks. Si ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · June 2023
IMPORTANCE: Peripartum separation of the pubic symphysis is a rare but potentially severe complication of childbirth, which may lead to prolonged immobilization. Thus, prompt diagnosis and treatment are paramount. OBJECTIVE: The purpose of this review is t ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · June 2023
IMPORTANCE: As prenatal care is in transition after the COVID-19 pandemic, reviewing fundamental physical examination approaches is necessary for providers examining obstetrical patients. OBJECTIVE: The objective of this review is 3-fold: (1) convey why th ...
Full textLink to itemCite
Journal articleAm J Obstet Gynecol · March 2023
Centers for Disease Control and Prevention data from 2020 demonstrate the continued upward trend in the mean age of pregnant individuals in the United States. Observational studies demonstrate that pregnancy in older individuals is associated with increase ...
Full textLink to itemCite
Journal articleAm J Obstet Gynecol · March 2023
Systemic lupus erythematosus (SLE) is a chronic, multisystem, inflammatory autoimmune disease characterized by relapses (commonly called "flares") and remission. Many organs may be involved, and although the manifestations are highly variable, the kidneys, ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · December 2022
IMPORTANCE: Group B Streptococcus (GBS) is a common pathogen with an effective treatment. However, it remains a significant cause of neonatal sepsis, morbidity, and mortality. The screening and management of this infection are some of the first concepts le ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · October 2022
IMPORTANCE: Cystic fibrosis (CF) is one of the most common autosomal recessive disorders. Carrier screening for CF should be offered to all women considering becoming pregnant or who are pregnant. Understanding the available screening tests, their limitati ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · September 2022
IMPORTANCE: The measurement of human chorionic gonadotropin (hCG) levels in different body fluids is a commonly utilized tool in obstetrics and gynecology, as well as other fields. It is often one of the first steps in the medical workup of female patients ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · August 2022
IMPORTANCE: Leiomyomata, or fibroids, are a common gynecological problem affecting many women of reproductive age. Historically, myomectomy is offered to women with symptomatic fibroids who desire to preserve fertility. More recently, uterine artery emboli ...
Full textLink to itemCite
Journal articleObstet Gynecol · August 1, 2022
Centers for Disease Control and Prevention data from 2020 demonstrate the continued upward trend in the mean age of pregnant individuals in the United States. Observational studies demonstrate that pregnancy in older individuals is associated with increase ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · July 2022
IMPORTANCE: The scientific benefits of breastfeeding for the parent and baby are clear, but the goal is often simplified to "breast is best." Patients' decisions to breastfeed are more nuanced than this approach implies, and it is essential for providers t ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · May 2022
IMPORTANCE: For patients who present with prelabor rupture of membrane (PROM) in the late preterm period (34 to 36 6/7 weeks), management remains unclear due to lack of consensus. However, recent guidelines have suggested that shared decision-making may be ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · April 2022
IMPORTANCE: Hypertensive complications of pregnancy comprise 16% of maternal deaths in developed countries and 7.4% of deaths in the United States. Rates of preeclampsia increased 25% from 1987 to 2004, and rates of severe preeclampsia have increased 6.7-f ...
Full textLink to itemCite
Journal articleAJP Rep · April 2022
Arhinia is a rare congenital anomaly that is not typically associated with known genetic mutations and is usually discovered after an affected infant is born. Prenatal diagnosis is important because neonates with arhinia often require specialized respirato ...
Full textOpen AccessLink to itemCite
Journal articleAm J Obstet Gynecol · March 2022
The use of assisted reproductive technology has increased in the United States in the past several decades. Although most of these pregnancies are uncomplicated, in vitro fertilization is associated with an increased risk for adverse perinatal outcomes pri ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · March 2022
IMPORTANCE: Ovarian cancer is the second most common gynecologic malignancy, but the most deadly female reproductive cancer in the United States. Epithelial ovarian cancer makes up approximately 90% of all cases and is responsible for more than 90% of ovar ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · December 2021
IMPORTANCE: Venomous snake and spider bites are relatively rare in the Unites States and even more so in the pregnant population. However, the impact of a venomous bite, also known as an envenomation, can be serious in a pregnant patient. Thus, providers i ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · November 2021
IMPORTANCE: Women undergoing cerclage placement remain at high risk for preterm labor and preterm prelabor rupture of membranes (PPROMs). The management of cervical cerclage after PPROM is controversial given the potential for prolonged latency when the ce ...
Full textLink to itemCite
Journal articleAm J Obstet Gynecol · October 2021
Soft markers were originally introduced to prenatal ultrasonography to improve the detection of trisomy 21 over that achievable with age-based and serum screening strategies. As prenatal genetic screening strategies have greatly evolved in the last 2 decad ...
Full textLink to itemCite
Journal articleAm J Obstet Gynecol · September 2021
In the United States, it is estimated that 1% to 4% of pregnant women are infected with hepatitis C virus, which carries approximately a 5% risk of transmission from mother to infant. Hepatitis C virus can be transmitted to the infant in utero or during th ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · August 2021
IMPORTANCE: Peripartum cardiomyopathy is a rare form of heart failure due to left ventricular systolic dysfunction that affects women late in pregnancy and the postpartum period. A diagnosis of exclusion, peripartum cardiomyopathy can be difficult to diagn ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · July 2021
IMPORTANCE: Adnexal masses are identified in approximately 0.05% to 2.4% of pregnancies, and more recent data note a higher incidence due to widespread use of antenatal ultrasound. Whereas most adnexal masses are benign, approximately 1% to 6% are malignan ...
Full textLink to itemCite
Journal articleAm J Obstet Gynecol · April 2021
The Society for Maternal-Fetal Medicine Publications Committee first adopted the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) system in 2013. This document provides an update on the Society for Maternal-Fetal Medicine Publicat ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · March 2021
IMPORTANCE: Spinal muscular atrophy (SMA) confers significant risk of neonatal and infant morbidity and mortality. Screening women during or before pregnancy for carrier status of SMA presents an opportunity to identify pregnancies at risk for this potenti ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · February 2021
IMPORTANCE: Intra-amniotic infection (IAI) is a common condition with potentially devastating maternal and neonatal complications. However, there are incomplete data regarding the most effective antimicrobial treatment regimen for this condition. OBJECTIVE ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · January 2021
IMPORTANCE: Up to 4% of all births in developed nations involve assisted reproductive technology (ART), along with other fertility treatment modalities. Thus, ART pregnancies constitute an important epidemiologic population with a known increased risk of c ...
Full textLink to itemCite
Journal articleF and S Reviews · January 1, 2021
In this review, we evaluate the different modalities of embryo genetic testing including preimplantation genetic testing for aneuploidy (PGT-A), for monogenic/single-gene abnormalities (PGT-M), and for chromosomal structural rearrangements (PGT-SR), with a ...
Full textCite
Journal articleObstet Gynecol Surv · September 2020
IMPORTANCE: Turner syndrome (TS) is one of the most common chromosomal abnormalities in women. The condition is characterized by gonadal dysgenesis and is associated with structural cardiac abnormalities. Assisted reproductive technology with oocyte donati ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · June 2020
IMPORTANCE: Infertility poses a substantial public health problem for women of reproductive age, in the United States and globally. Infertility can be overcome with a variety of emerging assisted reproductive technologies (ARTs). In vitro fertilization (IV ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · May 2020
IMPORTANCE: Prenatal genetic diagnosis can guide pregnancy management and decision making. Genetic diagnosis has advanced rapidly, and chromosomal microarray has become widely used, in addition to conventional karyotype. Exome sequencing may provide an eve ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · April 2020
IMPORTANCE: Poor sleep is widely recognized as a common complaint in pregnancy, and yet there are incomplete data on the exact nature of these complaints, what their implications for fetal and maternal health are, and how to best recognize and address thes ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · March 2020
IMPORTANCE: Approximately 10% to 16% of women meet diagnostic criteria for depression during pregnancy. Untreated maternal depression is associated with adverse pregnancy outcomes including premature birth, low birth weight, and fetal growth restriction. O ...
Full textLink to itemCite
Journal articleMenopause · February 2020
OBJECTIVE: The aim of the study was to review the role of hormone therapy in menopausal patients with breast cancer and gynecologic malignancies. METHODS: We searched MEDLINE (via PubMed) using a combination of keywords and database-specific subject headin ...
Full textOpen AccessLink to itemCite
Journal articleObstet Gynecol Surv · January 2020
IMPORTANCE: Hyperemesis gravidarum (HEG) affects 0.3% to 3% of pregnancies and requires additional therapies beyond those commonly used for less severe instances of nausea and vomiting of pregnancy (NVP). Differentiating between NVP and HEG is a vital yet ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · October 2019
IMPORTANCE: Postpartum venous thromboembolism (VTE) results in significant morbidity and mortality. The practicing obstetrician-gynecologist should have a plan for management and prevention. OBJECTIVE: The objective of this review is to familiarize obstetr ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · September 2019
IMPORTANCE: Since 2013, the United States has seen a rise in cases of congenital syphilis, culminating in a relative increase of 153% from 2013 to 2017 and 918 reported cases in 2017. In all, 50% to 80% of pregnant women with syphilis experience an adverse ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · August 2019
IMPORTANCE: Immune thrombocytopenia purpura (ITP), an autoimmune disease characterized by destruction of platelets, is a hematological disorder that can present in both pregnant and nonpregnant patients. Although thrombocytopenia in pregnancy can be caused ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · August 2019
IMPORTANCE: Congenital heart disease (CHD) is a common cause of neonatal morbidity and mortality. Several genetic abnormalities have been linked to congenital cardiac disease. When diagnosed prenatally, appropriate evaluation can help optimize neonatal out ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · June 2019
IMPORTANCE: Listeriosis is a rare foodborne condition that can cause serious health consequences in neonates and pregnant women. Listeria monocytogenes can be vertically transmitted to the fetus, resulting in adverse maternal, fetal, and neonatal outcomes. ...
Full textLink to itemCite
Journal articleJournal of Reproductive Medicine · June 1, 2019
BACKGROUND: Placental mesenchymal dysplasia (PMD) is a rare placental disorder characterized by placentomegaly. It carries a high incidence of adverse fetal outcomes, and its ultrasound appearance is similar to a partial hydatidiform mole and a complete hy ...
Cite
Journal articleObstet Gynecol Surv · May 2019
IMPORTANCE: Diabetes affects 6% to 9% of pregnancies, with gestational diabetes mellitus accounting for more than 90% of cases. Pregestational and gestational diabetes are associated with significant maternal and fetal risks; therefore, screening and treat ...
Full textLink to itemCite
Journal articleObstetrical and Gynecological Survey · April 1, 2019
Importance Acupuncture is a key component of therapy in traditional Chinese medicine. Only in the last few decades has acupuncture become popular in the United States. The mechanism behind acupuncture's effects on the body and brain has not been completely ...
Full textCite
Journal articleObstet Gynecol Surv · April 2019
IMPORTANCE: Acupuncture is a key component of therapy in traditional Chinese medicine. Only in the last few decades has acupuncture become popular in the United States. The mechanism behind acupuncture's effects on the body and brain has not been completel ...
Full textLink to itemCite
Journal articleMedEdPORTAL · January 18, 2019
INTRODUCTION: Genetics is ubiquitous in OB-GYN. However, data suggest that trainees feel underprepared to counsel patients about genetic testing, the nuances of which are becoming increasingly complicated. We sought to develop and implement a genetics curr ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · January 2019
IMPORTANCE: Preterm delivery represents an important cause of infant morbidity and mortality. Various tocolytics have been studied with the objective of stopping preterm labor, increasing gestational age at delivery, and preventing complications related to ...
Full textLink to itemCite
Journal articleJ Matern Fetal Neonatal Med · September 2018
PURPOSE: Describe practice patterns among obstetrician/gynecologists (OB/GYNs) when caring for women with pregnancy complicated by fetal trisomy 13 (T13) or 18 (T18) and compare these between maternal-fetal medicine (MFM) and non-MFM providers. MATERIALS A ...
Full textLink to itemCite
Journal articleJ Matern Fetal Neonatal Med · August 2018
PURPOSE: To describe the rate and severity of gestational hypertensive disorders (GHDs) in pregnancies complicated by trisomy 13 (T13). MATERIALS AND METHODS: Retrospective cohort study of singleton deliveries in California from 2005 to 2008 using vital st ...
Full textLink to itemCite
Journal articleSemin Perinatol · August 2018
Prenatal care providers are faced with a myriad of decisions about how to offer genetic screening and testing in ways that are appropriate to their patient population and their workflow. Among the critical issues brought to the forefront of rapidly advanci ...
Full textLink to itemCite
Journal articleAm J Obstet Gynecol · July 2018
Ventriculomegaly is defined as dilation of the fetal cerebral ventricles and is a relatively common finding on prenatal ultrasound. The purpose of this document is to review the diagnosis, evaluation, and management of mild fetal ventriculomegaly. When enl ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · July 2018
IMPORTANCE: There are approximately 284,500 adolescent and adult women living with human immunodeficiency virus (HIV) in the United States. It is estimated that approximately 8500 of these women give birth annually. While the rate of perinatal transmission ...
Full textLink to itemCite
Journal articleClin Obstet Gynecol · June 2018
Pulmonary embolism in pregnancy is a leading cause of maternal mortality. The clinical presentation is often nonspecific, making imaging essential for accurate diagnosis. After reviewing the literature on the radiologic diagnosis of pulmonary embolism in p ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · June 2018
IMPORTANCE: Inherited metabolic disorders, or inborn errors of metabolism, can result in significant morbidity and mortality. Advances in genetic testing, including newborn screening and prenatal carrier screening, continue to increase awareness and highli ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · February 2018
IMPORTANCE: Intrahepatic cholestasis of pregnancy (ICP) complicates approximately 0.2% to 2% of pregnancies and can lead to increased fetal risks in pregnancy. OBJECTIVE: This review aims to increase the knowledge of women's health care providers regarding ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · February 2018
OBJECTIVE: Congenital heart defects represent the most common major congenital anomalies. The objective of this review was to define the most common forms of congenital heart disease (CHD) in pregnancy, outline preconception counseling, discuss the associa ...
Full textLink to itemCite
Journal articleAm J Obstet Gynecol · November 2017
In the United States, 1-2.5% of pregnant women are infected with hepatitis C virus, which carries an approximately 5% risk of transmission from mother to infant. Hepatitis C virus can be transmitted to the infant in utero or during the peripartum period, a ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · October 2017
IMPORTANCE: The rapid development of prenatal genetic testing and screening tools and choices constantly challenges clinicians to stay up to date on current best practice. OBJECTIVE: We sought to review, compare, and summarize recent national society guide ...
Full textLink to itemCite
Journal articleObstet Gynecol · September 2017
Myelomeningocele, a severe form of spina bifida, occurs in approximately 1 in 3,000 live births in the United States. The extent of disability is generally related to the level of the myelomeningocele defect, with a higher upper level of lesion generally c ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · August 2017
BACKGROUND: Conservative excisional measures used to manage cervical dysplasia are often cited as risk factors for preterm labor in subsequent pregnancies. OBJECTIVE: We performed an evidence-based review of the obstetric complications following excisional ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · August 2017
IMPORTANCE: Superobesity, defined as body mass index 50 kg/m2 or greater, is the fastest-growing obesity group in the United States. Currently, 2% of pregnant women in the United States are superobese, and 50% will deliver via cesarean delivery. OBJECTIVE: ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · June 2017
IMPORTANCE: An estimated 1% to 2.5% of pregnant women in the United States are infected with hepatitis C virus (HCV), which carries approximately a 6% risk of mother-to-infant transmission. OBJECTIVES: The aims of this article are to review the current evi ...
Full textLink to itemCite
Journal articleAm J Obstet Gynecol · March 2017
The introduction of cell-free DNA screening for aneuploidy into obstetric practice in 2011 revolutionized the strategies utilized for prenatal testing. The purpose of this document is to review the current data on the role of ultrasound in women who have u ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · March 2017
IMPORTANCE: Congenital uterine anomalies (CUAs) are strongly associated with adverse fertility and pregnancy outcomes. Health care providers must be able to diagnose these anomalies, understand their impact, and counsel women on interventions that might im ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · February 2017
IMPORTANCE: Major congenital abnormalities, or birth defects, carry significant medical, surgical, cosmetic, or lifestyle consequences. Such abnormalities may be syndromic, involving multiple organ systems, or can be isolated. Overall, 2% to 4% of live bir ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · January 2017
Congenital heart disease (CHD) occurs in 4-13 per 1000 births in the United States. While many risk factors for CHD have been identified, more than 90% of cases occur in low-risk patients. Guidelines for fetal cardiac screening during the second trimester ...
Full textLink to itemCite
Journal articleAm J Obstet Gynecol · October 2016
Chromosomal microarray analysis is a high-resolution, whole-genome technique used to identify chromosomal abnormalities, including those detected by conventional cytogenetic techniques, as well as small submicroscopic deletions and duplications referred to ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · September 2016
We performed an evidence-based review of the obstetrical management of gastroschisis. Gastroschisis is an abdominal wall defect, which has increased in frequency in recent decades. There is variation of prevalence by ethnicity and several known maternal ri ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · August 2016
Screening for fetal aneuploidy in pregnant women using cell-free DNA has increased dramatically since the technology became commercially available in 2011. Since that time, numerous trials have demonstrated high sensitivity and specificity to screen for co ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · June 2016
Obesity is a source of major morbidity and mortality and is a growing concern worldwide. Maternal obesity is associated with increased maternal and fetal risks during pregnancy. Bariatric surgery has emerged as one of the most sustainable treatments for se ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · May 2016
Pregnancies complicated by trisomy 13 (T13) or trisomy 18 (T18) present unique challenges for obstetric management. From the initial diagnosis, the task of counseling these women and families is difficult because fetal and neonatal outcomes vary depending ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · January 2016
The incidence of congenital heart disease is most commonly reported in 8 per 1000 live births. Situs anomalies are among the least common forms of congenital heart disease. This study defines situs and describes the variations of fetal situs anomalies. Sit ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · December 2015
As the average age that women have their first child increases and cancer therapies improve survival, obstetricians are more likely to care for pregnant women who have survived cancer. Managing these pregnancies can be challenging, as they may be associate ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · August 2015
Congenital atrioventricular block (CAVB) affects approximately 2% of fetuses of mothers with anti-Ro or anti-La antibodies, regardless of maternal rheumatologic symptoms. Anti-Ro and anti-La antibodies are antinuclear antibodies commonly found in autoimmun ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · July 2015
Chikungunya fever is an increasingly common viral infection transmitted to humans by species of the Aedes mosquitoes. Characterized by fevers, myalgias, arthralgias, headache, and rash, the infection is endemic to tropical areas. However, identification of ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · May 2014
Although uncommon, the incidence of cancer complicating pregnancy is increasing. Managing these pregnancies creates many diagnostic, therapeutic, and ethical dilemmas for the patient, her family, and the medical care team. Despite concerns for fetal well-b ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · September 2013
Arthropod-borne bacterial diseases affect more than 25,000 Americans every year and thousands more around the world. These infections present a diagnostic dilemma for clinicians because they mimic many other pathologic conditions and are often low on or ab ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · September 2012
Fetal growth restriction is a complex problem in modern obstetrics. It is a condition of suboptimal fetal growth based on a genetically predetermined potential and affects approximately 5% to 10% of pregnancies. It is traditionally defined as an estimated ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · June 2012
Familial Mediterranean fever (FMF) is the most common hereditary recurrent febrile disorder, characterized by the sudden onset of high fever and severe abdominal pain. The implications of this disorder on a woman's health are significant and not well known ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · April 2012
UNLABELLED: Vaccinations in pregnancy are an important aspect of prenatal care and of improving not only maternal health but also neonatal outcomes. Only 2 vaccines are specifically recommended during pregnancy: influenza and tetanus, diphtheria, and acell ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · December 2011
UNLABELLED: Perinatal depression is an increasingly common comorbidity of pregnancy and is associated with adverse birth outcomes. Newer classes of antidepressants have been developed with a variety of mechanisms and improved side effect profiles. There is ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · September 2011
UNLABELLED: Valvular heart disease is common in pregnancy. Maternal physiology changes significantly during gestation with substantial increases in cardiac output and blood volume; this can cause unmasking or worsening of cardiac disease. Acquired valvular ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · August 2011
UNLABELLED: Parasitic infections affect tens of millions of pregnant women worldwide. These infections lead directly and indirectly to a spectrum of adverse maternal and fetal/placental effects. With the increase in global travel, healthcare providers will ...
Full textLink to itemCite
Journal articleGynecol Obstet Invest · 2005
Featured Publication
Screening for aneuploidy has traditionally been reserved for women of advanced maternal age. More recent advances in serum screening and ultrasound technology have allowed women of all ages to be offered screening in the second and even first trimester. Th ...
Full textLink to itemCite
Journal articleJournal of Diagnostic Medical Sonography · November 1, 2004
This case report demonstrates a complex fetal ovarian cyst. A fetal ovarian cyst is a fluid-filled ovarian tumor. Ovarian cysts are rarely detected in infants but are slightly more common on fetal sonography. The majority of cysts are benign corpus luteal ...
Full textCite
Journal articleAm J Obstet Gynecol · January 2004
Featured Publication
OBJECTIVE: This study was undertaken to examine neonatal outcomes in karyotypically normal cases of omphalocele with respect to mode of delivery, presence of associated anomalies, presence of extracorporeal liver, and method of abdominal wall closure. STUD ...
Full textLink to itemCite
Journal articleAm J Obstet Gynecol · December 2003
Featured Publication
OBJECTIVES: The purpose of this study was to examine the relationship between labor and ruptured membranes on the neonatal outcome of infants with gastroschisis. STUDY DESIGN: We reviewed the outcomes of 60 neonates who were prenatally diagnosed with gastr ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · October 2002
Featured Publication
Inherited and acquired thrombophilias have been associated with recurrent pregnancy loss. Over recent years our ability to detect protein and genetic abnormalities responsible for thrombotic tendency has improved. We are now left with the task of decipheri ...
Full textLink to itemCite
Journal articleObstet Gynecol · May 2002
Featured Publication
BACKGROUND: Wernicke's encephalopathy is usually associated with alcohol abuse, but can also occur with hyperemesis gravidarum. The effect of delay in thiamine replacement on fetal outcomes is unknown. We present a case of this complication. CASE: A primip ...
Full textLink to itemCite
Journal articleJ Soc Gynecol Investig · 2002
OBJECTIVE: To determine whether magnetic resonance imaging (MRI) and ultrasound (US) are effective methods for diagnosing placenta accreta, increta, or percreta antenatally. METHODS: We retrospectively reviewed radiologic reports of patients who had the di ...
Full textLink to itemCite
Journal articleHum Reprod · August 2001
Featured Publication
We wished to determine how clinicians manage sperm donors whose offspring have chromosomal or structural abnormalities. A directed, multiple-choice survey was given to reproductive endocrinologists and obstetrical geneticists to assess management of sperm ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · May 2001
Featured Publication
A growing number of transplant recipients are women of reproductive age or children who will reach reproductive age. Thus, menstrual function and pregnancy increasingly are important issues because fertility is restored to women who were previously unable ...
Full textLink to itemCite
Journal articleAm J Obstet Gynecol · May 2001
Featured Publication
OBJECTIVE: Our aim was to review our experience with renal biopsy in pregnancy. STUDY DESIGN: We reviewed 18 renal biopsies performed during pregnancy or in the immediate postpartum period at the University of North Carolina. Indications, histopathologic f ...
Full textLink to itemCite
Journal articleAm J Obstet Gynecol · June 2000
Featured Publication
OBJECTIVE: This study was undertaken to characterize aspects of the natural history of eclampsia. STUDY DESIGN: A retrospective analysis was performed on the records of patients with eclampsia who were delivered at two tertiary care hospitals. RESULTS: Fif ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · August 1999
UNLABELLED: Peripartum cardiomyopathy (PPCM) is a poorly characterized, rare form of cardiomyopathy. The etiology of PPCM is unknown, but viral, autoimmune, and idiopathic causes may contribute. The presentation is similar to other forms of congestive hear ...
Full textLink to itemCite
Journal articleAm J Obstet Gynecol · August 1999
Featured Publication
OBJECTIVE: Pregnancy and childbirth are commonly thought to be associated with the development of urinary incontinence and lower urinary tract symptoms. The purpose of this study was to assess the relationship, if any, between pregnancy and the development ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · June 1999
Featured Publication
The optimal management of preterm premature rupture of membranes (PPROM) in a patient with a cerclage is controversial. The issues are whether the latency period between rupture of membranes and delivery is decreased if the cerclage is removed and whether ...
Full textLink to itemCite
Journal articleObstet Gynecol · April 1999
Featured Publication
OBJECTIVE: To determine if obstetrician-gynecologists are ready to comply with the April 1997 National Institutes of Health (NIH) consensus statement regarding carrier screening for cystic fibrosis. METHODS: A multiple-choice questionnaire was mailed to al ...
Full textLink to itemCite
Journal articleJ Soc Gynecol Investig · 1999
Featured Publication
OBJECTIVE: Atosiban is a selective oxytocin receptor antagonist capable of inhibiting oxytocin-induced contractility of the uterus. Trials of this agent in intact animals and women as a tocolytic agent for preterm labor have shown atosiban to be devoid of ...
Link to itemCite
Journal articleAm J Perinatol · 1999
Sacrococcygeal teratoma is the most common fetal neoplasm, with an incidence of 1 in 40,000 births. Fetuses with this malformation are at risk for significant perinatal morbidity and mortality. We identified nine fetuses with sacrococcygeal teratomas that ...
Full textLink to itemCite
Journal articlePrenat Diagn · September 1998
Featured Publication
While the clinical features associated with full trisomy 13 have been well characterized, the clinical outcome associated with mosaic trisomy 13 is much less clear. The medical literature reports a broad range of possible clinical outcomes from severe ment ...
Full textLink to itemCite
Journal articleJ Clin Anesth · February 1998
STUDY OBJECTIVE: To analyze the effects of epidural analgesia for labor when dystocia occurs. DESIGN: Retrospective cohort study. SETTING: Academic health center. PATIENTS: 641 low risk, nulliparous women in spontaneous labor. INTERVENTIONS: 406 (63%) wome ...
Full textLink to itemCite
Journal articleJ Perinatol · 1998
Featured Publication
OBJECTIVE: Pregnancies of women with systemic lupus erythematosus (SLE) were studied to assess the effects interaction of this disease and pregnancy. STUDY DESIGN: Charts of pregnant women with a discharge diagnosis of lupus were reviewed. Inclusion criter ...
Link to itemCite
Journal articleObstet Gynecol · December 1997
OBJECTIVE: To determine the magnitude of the risk and the predictive clinical characteristics for development of preeclampsia when triploidy is diagnosed in the second trimester. METHODS: A retrospective analysis of databases maintained by the cytogenetics ...
Full textLink to itemCite
Journal articleAm J Perinatol · October 1997
Childbirth is thought to be an important cause of pelvic floor dysfunction. Heretofore, this has been thought due to pudendal denervation. Endovaginal sonography allows thorough assessment of the anorectum and in this study was used to assess nulliparous w ...
Full textLink to itemCite
Journal articleDrug Saf · August 1997
For most agents with CNS activity, there are limited data regarding their safety in breastfeeding. Any decision to institute treatment for a neurological or psychiatric disorder must weigh the benefits of maternal treatment against the potential harm to th ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · July 1997
Current prenatal diagnosis relies on invasive methods such as amniocentesis and chorionic villus sampling. Because these methods carry a low, but finite risk of pregnancy loss, noninvasive genetic screening techniques are the focus of intense research. Iso ...
Full textLink to itemCite
Journal articleAm J Obstet Gynecol · May 1997
OBJECTIVE: Our purpose was to measure any short-term effects that the transdermal nicotine replacement system may have in pregnancy and to verify salivary nicotine and cotinine levels during patch placement. STUDY DESIGN: After customary smoking cessation ...
Full textLink to itemCite
Journal articleObstet Gynecol · April 1997
OBJECTIVE: To compare perinatal outcome in older oocyte recipients with that in women of advanced maternal age who conceived without assisted reproductive technologies. METHODS: We performed a retrospective cohort study of 46 oocyte recipients and 49 women ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · March 1997
Calcium channel antagonists are widely prescribed in obstetrics and gynecology for blood pressure control and tocolysis. Concerns have recently arisen regarding the safety of these agents. Several studies found that short-acting forms of calcium channel bl ...
Full textLink to itemCite
Journal articleObstet Gynecol · February 1997
Human placental cord blood contains a large number of hematopoietic progenitor cells, which could be used as a source of stem cells for the treatment of hematologic disorders and malignancies. Advantages of cord blood use include noninvasive collection, lo ...
Full textLink to itemCite
Journal articleAmerican Journal of Perinatology · 1997
Childbirth is thought to be an important cause of pelvic floor dysfunction. Heretofore, this has been thought due to pudendal denervation. Endovaginal sonography allows thorough assessment of the anorectum and in this study was used to assess nulliparous w ...
Cite
Journal articleAm J Perinatol · November 1996
An aneurysm of the vein of Galen is a rare arteriovenous malformation of the central nervous system. Fetal manifestations have included nonimmune hydrops, hydrocephalus, and intracranial hemorrhage. This anomaly may be diagnosed prenatally by several imagi ...
Full textLink to itemCite
Journal articleObstet Gynecol · October 1996
BACKGROUND: Studies on the importance of prenatal ultrasonographic findings in gastroschisis have shown variable significance in predicting neonatal outcome. We report two cases of short bowel syndrome and poor neonatal outcome that had interesting prenata ...
Full textLink to itemCite
Journal articleAm Fam Physician · August 1996
A post-term pregnancy is one that lasts beyond 42 weeks of confirmed gestational age. The goal of management in the post-term pregnancy is to avoid stillbirth, meconium aspiration and neonatal death. Ultrasonography obtained at term does not accurately pre ...
Link to itemCite
Journal articleAm J Obstet Gynecol · August 1996
OBJECTIVE: Smoking in pregnancy is the foremost cause of preventable perinatal mortality. We have demonstrated that a behavioral intervention can alter smoking in pregnant women. We tested the utility of this intervention at multiple sites in varied settin ...
Full textLink to itemCite
Journal articleJ Reprod Med · July 1996
BACKGROUND: Lupus, one of the most common autoimmune diseases in pregnancy, may involve multiple organ systems with varying severity. The diagnosis and treatment of the disease may be complicated by the physiologic changes of pregnancy. CASE: A 22-year-old ...
Link to itemCite
Journal articleObstet Gynecol Surv · June 1996
We reviewed existing data on fetal abnormalities to provide guidelines to determine which conditions have an improved neonatal outcome by cesarean delivery. We used Medline database to search for English language papers on a variety of fetal conditions tha ...
Full textLink to itemCite
Journal articleObstet Gynecol · May 1996
BACKGROUND: Teratomas of the head and neck are rare and occur almost exclusively in neonates. Prenatal diagnosis of these tumors allows for a carefully planned delivery that maintains an open airway and potentially improves perinatal outcome. We report the ...
Link to itemCite
Journal articleObstet Gynecol · May 1996
OBJECTIVE: To review published data pertaining to safety of psychoactive drugs used to treat psychiatric disorders during pregnancy and lactation. DATA SOURCES: A computerized search of articles published through July 1995 was performed on the MEDLINE data ...
Full textLink to itemCite
Journal articleClin Genet · April 1996
After ultrasound diagnosis of a fetus with severe hydrocephalus and Dandy-Walker malformation, amniocentesis revealed chromosomal mosaicism for dup(lq) and del(Xq). The neonate had dysmorphic facial features, vertebral abnormalities, and pulmonary hypoplas ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · February 1996
Cancer is an important cause of death in the United States in women of childbearing age. Approximately 1 per 1000 pregnant women will develop cancer. This review (Part II follows in this issue) examines the diagnosis, prognosis, and management of cancer du ...
Full textLink to itemCite
Journal articleAm J Perinatol · February 1996
Patients with Goodpasture syndrome have classically had decreased fertility and associated pregnancy wastage. Renal transplantation can increase the likelihood of successful pregnancy. We describe a patient who carried a pregnancy into the third trimester ...
Full textLink to itemCite
Journal articleAm J Perinatol · January 1996
The association between fetal parvovirus B19 infection and hydrops was first reported in 1984. The virus has a predilection for the erythroid cell line, which in the fetus may produce anemia. Recent cases of parvovirus infection in other fetal cell lines h ...
Full textLink to itemCite
Journal articleInt Urogynecol J Pelvic Floor Dysfunct · 1996
Magnetic resonance imaging (MRI) was used to assess anatomical changes in the pelvic floor after childbirth. Six women underwent serial MRI examination within 30 hours and at 1 week, 2 weeks, 6 weeks and 6 months after delivery; 8 additional women were stu ...
Full textLink to itemCite
Journal articleJ Perinatol · 1996
Fetal and neonatal ovarian cysts can be small asymptomatic lucencies or large symptomatic echocomplex masses that can cause intestinal obstruction and peritonitis. Solid masses are the most rare form of ovarian cysts. A fetus, anatomically unremarkable at ...
Link to itemCite
Journal articleAm Fam Physician · December 1995
A variety of options for prenatal diagnosis are available to the pregnant woman. Maternal serum analyte analysis, performed between 15 and 20 weeks' gestation, provides a screening test for fetal neural tube defects and aneuploidy in low-risk pregnancies. ...
Link to itemCite
Journal articleWest J Med · November 1995
To determine the characteristics of maternal varicella at our institution, we reviewed all cases of primary varicella in pregnancy. Using a perinatal database that summarizes all obstetric admissions, we reviewed the medical records of women with varicella ...
Link to itemCite
Journal articleAm J Perinatol · September 1995
Myocardial infarction associated with pregnancy is a relatively rare event, usually related to maternal risk factors for ischemic heart disease such as hypertension and diabetes mellitus. Coronary artery dissection represents an even more uncommon event an ...
Full textLink to itemCite
Journal articleAm J Perinatol · September 1995
Alpha1-antitrypsin deficiency is an inherited pulmonary disorder which results from a deficiency of a major plasma protease inhibitor. The onset and severity of symptoms vary widely and depend on the genotype and whether the patient smokes cigarettes. Alph ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · September 1995
Porencephaly may result from either a developmental anomaly or an antepartum intraparenchymal insult. Pre- and postnatal ultrasonography can demonstrate characteristic images of porencephaly. There is minimal literature on diagnosis and outcome of antenata ...
Full textLink to itemCite
Journal articleObstet Gynecol · July 1995
The terminology we employ influences our perceptions. Thus, we believe in reviewing terminology regularly. The term "cesarean section" should be abandoned. A medical procedure is rarely named after a historic figure, and almost never after an ancient Roman ...
Full textLink to itemCite
Journal articleObstet Gynecol Surv · June 1995
It is proposed that clinicians screen all pregnant women at high risk for preterm labor and premature rupture of membranes for bacterial vaginosis, and treat all women when it is diagnosed. This infection is associated with a two to three times increase in ...
Full textLink to itemCite
Journal articleEur J Obstet Gynecol Reprod Biol · June 1995
Until very recently cervical pregnancies have been treated with surgery, usually hysterectomy. The development of endovaginal ultrasound, which allows early diagnosis, and methotrexate chemotherapy have opened up new therapeutic options. A 45-year-old mult ...
Full textLink to itemCite
Journal articleObstet Gynecol · May 1995
BACKGROUND: There has been one reported case of porencephaly diagnosed postnatally as a result of amniocentesis. We report the first antenatal diagnosis of porencephaly, which apparently resulted from penetration of the fetal skull during amniocentesis. CA ...
Full textLink to itemCite
Journal articleObstet Gynecol · May 1995
BACKGROUND: Fetal lymphangiomas can occur in many different anatomic locations, including the most commonly seen nuchal cystic hygroma. CASE: A fetus at 18 weeks' gestation was found to have a massive right axillary hygroma. The fetal karyotype was normal. ...
Full textLink to itemCite
Journal articleRadiology · April 1995
PURPOSE: To demonstrate the normal involution process of the post-partum pelvis with serial magnetic resonance (MR) imaging. MATERIALS AND METHODS: MR imaging was performed in 14 women after uncomplicated vaginal delivery. Six women underwent serial MR exa ...
Full textLink to itemCite
Journal articleObstet Gynecol · April 1995
OBJECTIVE: To analyze the etiologies and outcomes for a southeastern section of the United States, and to organize an efficient approach to evaluation. METHODS: We reviewed 82 cases of non-immune hydrops presenting after 20 weeks' gestation over a 10-year ...
Full textLink to itemCite
Journal articleAm J Perinatol · March 1995
We evaluated the pregnancy outcome of all patients with elevations of both maternal serum alpha-fetoprotein and human chorionic gonadotropin since institution of combined serum screening at our program. After analysis of 34,404 samples, 99 patients were fo ...
Full textLink to itemCite
Journal articleJournal of Maternal Fetal and Neonatal Medicine · January 1, 1995
Romano-Ward syndrome is an unusual and potentially devastating disorder manifested by prolongation of the QT interval. Persons with this syndrome are at risk for sudden death from ventricular dysrhythmis. A case of a gravid woman with the disorder is prese ...
Full textCite
Journal articlePrimary Care Update for Ob Gyns · January 1, 1995
Medical genetics is the most rapidly expanding field in medicine. The obstetrician/gynecologist frequently encounters patients with genetic issues that must be evaluated and may require consultation with a specialist. Commonly encountered problems include ...
Full textCite
Journal articleAmerican Journal of Perinatology · 1995
Alpha1-antitrypsin deficiency is an inherited pulmonary disorder which results from a deficiency of a major plasma protease inhibitor. The onset and severity of symptoms vary widely and depend on the genotype and whether the patient smokes cigarettes. Alph ...
Cite
Journal articleBirth · December 1994
Ancient cultures have applied a variety of fascinating therapies to prevent the occurrence and reoccurrence of miscarriage. Ceremonies of ritual purification, special prayers, and a variety of medicinal therapies were employed throughout the ages to preven ...
Full textLink to itemCite
Journal articlePrenat Diagn · November 1994
Bilateral renal agenesis is a lethal congenital anomaly. It appears to be transmitted in a polygenic pattern. The prenatal ultrasound findings consist of severe oligohydramnios, absence of the fetal bladder, and failure to identify fetal kidneys. Twin gest ...
Full textLink to itemCite
Journal articleAm J Perinatol · November 1994
The perinatologists are emerging as the physicians who evaluate and treat women with recurrent pregnancy loss. Recurrent miscarriage, previously referred to as habitual abortion, affects almost 1% of couples. The etiologies of recurrent miscarriage are div ...
Full textLink to itemCite
Journal articleAm J Perinatol · November 1994
Premature closure of the foramen ovale is a rare cardiac anomaly. Severe right-sided heart failure accounts for the hepatomegaly, ascites, pleural and pericardial effusions, and generalized edema of these hydropic fetuses. Premature closure of the foramen ...
Full textLink to itemCite
Journal articleClin Pediatr (Phila) · September 1994
X-linked ornithine transcarbamylase deficiency (OTCD) often leads to fatal neonatal hyperammonemia in affected males (hemizygotes). In prenatal management of subsequent pregnancies, families carrying female fetuses are often reassured of the low risk of cl ...
Full textLink to itemCite
Journal articleTeratology · August 1994
Sirenomelia, which has been reported for more than 450 years, is the most severe form of caudal dysplasia. This disorder is classically associated with agenesis or severe dysplasia of the urinary tract. A 27-year-old gravida 3 para 0020 presented at 19 wee ...
Full textLink to itemCite
Journal articleAm J Perinatol · July 1994
Our case demonstrates that nonimmune hydrops and hydrocephalus may be associated by the common pathway of intracranial hemorrhage and the development of anemia. The anemia apparently resulted in cardiomegaly with pericardial effusion and ascites as well as ...
Full textLink to itemCite
Journal articleJ Reprod Med · June 1994
Seventy-six parturients with a clinical diagnosis of early postpartum endometritis were randomized to be treated with either standard therapy--ampicillin, gentamicin and clindamycin--or a new regimen, ampicillin/sulbactam. We deliberately chose to administ ...
Link to itemCite
Journal articleObstet Gynecol · May 1994
BACKGROUND: Nevus sebaceous is a congenital hamartomatous skin lesion that is commonly associated with other abnormalities and is most frequently located on the face and head. To our knowledge, there are no previous reports of the ultrasonographic appearan ...
Link to itemCite
Journal articleGynecol Obstet Invest · 1994
The frequency and volume of transplacental hemorrhage that occurs with threatened abortions is unknown. The use of Rh immune globulin for such patients is therefore undefined. We studied the incidence and quantity of transplacental hemorrhage in patients w ...
Full textLink to itemCite
Journal articleN Engl J Med · November 25, 1993
BACKGROUND: The use of indomethacin as a tocolytic agent in pregnant women appears to be accompanied by a low incidence of neonatal complications. However, the neonatal effects of indomethacin have been studied primarily in infants born after 32 weeks' ges ...
Full textLink to itemCite
Journal articleTeratology · November 1993
Thirty two infants referred for in-patient genetics evaluation at the University of California at San Francisco, 1987-1992, were found to have a history of maternal cocaine use. Genetics reports and medical records were reviewed on all these infants to ide ...
Full textLink to itemCite
Journal articleGynecol Obstet Invest · 1993
Accurate assessment of gestational age and fetal weight in the pregnant ewe is important in both acute and longitudinal perinatal studies. We describe two morphometric methods based on the length of the fetal metatarsal bone. These measurements can be made ...
Full textLink to itemCite
Journal articleAm J Perinatol · July 1992
Space-occupying lesions within the fetal thorax are associated with poor perinatal outcome. Therefore some investigators have suggested in utero treatment. We describe a case of a fetus with a large intrathoracic mass that was noted to decrease markedly in ...
Full textLink to itemCite
Journal articleAm J Med Genet · June 1, 1992
We report 3 cases of Pallister-Hall syndrome involving hypothalamic hamartoblastoma, hypopituitarism, cranial, and limb abnormalities. The first 2 cases represent the first apparent sibs reported with this syndrome. Patient 1 represents the first known pat ...
Full textLink to itemCite
Journal articleObstet Gynecol · May 1992
Goodpasture syndrome is characterized by pulmonary hemorrhage, glomerulonephritis, and an autoantibody to glomerular basement membrane antigens. Current management of this potentially lethal disease consists of glucocorticoids to control pulmonary hemorrha ...
Link to itemCite
Journal articleHum Genet · 1992
Prenatal diagnosis and carrier detection for Duchenne muscular dystrophy (DMD) usually can be performed using DNA analysis. When recombination occurs within the DMD gene, or DNA analysis is uninformative, or in pedigrees where it is unclear whether or not ...
Full textLink to itemCite
Journal articleJ Perinatol · September 1991
Teratomas are the most common congenital neoplasm. Fetal intracranial teratomas generally are large solid/cystic tumors that often completely replace normal brain tissue. Mediastinal teratomas are uncommon and rarely result in nonimmune hydrops fetalis. We ...
Link to itemCite
Journal articleJ Perinatol · June 1991
We sought to determine whether the recent Centers for Disease Control recommendation of universal prenatal screening for hepatitis B surface antigen (HBsAg) is necessary or cost-effective in a population of private patients. During the 21 months of our stu ...
Link to itemCite
Journal articleSurg Gynecol Obstet · April 1991
Technologic advances in ultrasound have led to the ability to access the fetal circulation in utero. Precise evaluation and accurate treatment of fetal hemolytic disease is now possible. This technique of in utero intravascular transfusion has several adva ...
Link to itemCite
Journal articleObstet Gynecol · October 1990
Successful treatment of severe fetal hemolytic disease depends on rapid and accurate measurement of fetal hemoglobin or hematocrit. The HemoCue is a portable hemoglobinometer that rapidly measures hemoglobin concentration. To evaluate the potential role of ...
Link to itemCite
Journal articleAm J Perinatol · July 1990
A case of hyperparathyroidism complicating pregnancy is described. An uncommon associated finding of hypokalemia and its possible etiology is discussed. When hypokalemia occurs in the setting of hyperparathyroidism, oral phosphates should be used with caut ...
Full textLink to itemCite
Journal articleAm J Obstet Gynecol · January 1990
To our knowledge, this is the first case of vulvar leiomyosarcoma occurring during pregnancy to be reported. The neoplasm was resected immediately after a term vaginal delivery. A wide local excision of the vulva with bilateral superficial inguinal node sa ...
Full textLink to itemCite
Journal articleObstet Gynecol · September 1988
Osteogenesis imperfecta is the common term for a heterogeneous group of heritable disorders of connective tissue with lethal and nonlethal forms. Prenatal diagnosis presents difficult medical and ethical issues. Of concern are the following: 1) the certain ...
Link to itemCite