Scholars@Duke
Kyle McPherson

Scholarly Works - Journal articles

The insulin-like peptides Dilp2 and Dilp6 exhibit divergent responses to dietary sugar and protein in <i>Drosophila</i> larvae.

Journal article Proceedings of the National Academy of Sciences of the United States of America · October 2025 Nutrient intake drives secretion of insulin and insulin-like peptides that stimulate anabolic metabolism and tissue growth. Eight Drosophila insulin-like peptides (Dilps) are encoded in the Drosophila genome; whether these Dilps respond unifo ... Full text Cite

Truncated complement factor H Y402 gene therapy rescues C3 glomerulonephritis.

Journal article Mol Ther · August 6, 2025 There are no effective therapies for patients with dry age-related macular degeneration (AMD) or C3 glomerulonephritis (C3G). Unfortunately, past efforts to treat C3G using exogenous human complement factor H (CFH) found limited success due to immune rejec ... Full text Link to item Cite