Lawrence Simeon Barak | Scholars@Duke

Lawrence Simeon Barak
Associate Research Professor of Cell Biology

Current Appointments & Affiliations

Associate Research Professor of Cell Biology, Cell Biology, Basic Science Departments 2003

Contact Information

483 Clin & Res Labs, Durham, NC 27710
Duke Box 3287, Durham, NC 27710
l.barak@cellbio.duke.edu (919) 681-4549

Background
Education, Training, & Certifications
- M.D., University of Michigan at Ann Arbor 1982
- Ph.D., Cornell University 1982
Duke Appointment History
- Assistant Research Professor of Cell Biology, Cell Biology, Basic Science Departments 1998 - 2003
Research
Selected Grants
- Establishing the molecular and cellular mechanisms of Lgr5 signaling for controlling cancer stem cell behavior awarded by National Institutes of Health 2017 - 2020
- Biased Agonism at Neurotensin Receptor 1 for the Treatment of Methamphetamine Addiction awarded by National Institutes of Health 2017 - 2020
- Inhibition of Wnt/B-Catenin Signaling in Colorectal Cancer Therapy awarded by National Institutes of Health 2013 - 2019
- Drug Abuse: Discovering Ligands for Pertinent GPCRs awarded by National Institutes of Health 2010 - 2019
- A Cancer Rainbow Mouse for Simultaneous Assessment of Multiple Oncogenes awarded by National Institutes of Health 2015 - 2018
- Screening and identification of beta-arrestin biased dopamine receptor ligands for PD symptom therapy. awarded by Michael J. Fox Foundation for Parkinson's Research 2016
- Beta-arrestin Regulation of Ghrelin Signaling in Modulating Addictive Behavior awarded by National Institutes of Health 2014 - 2016
- Novel high-throughput screening for modifiers of TorsinA pathology awarded by National Institutes of Health 2013 - 2015
- A Cancer Rainbow Mouse for the Simultaneous Assessment of Multiple Oncogenes awarded by National Institutes of Health 2012 - 2015
- Discovering Ligands for a5-a3-b4 Nicotinic Acetylcholine Receptors. awarded by National Institutes of Health 2010 - 2014
- Small molecule screen to enhance epithelial repair awarded by National Institutes of Health 2011 - 2012
- Small Molecule Agonsists for the Neurotensin 1 Receptor awarded by National Institutes of Health 2009 - 2012
- Drug Abuse: Discovering Ligands for Pertinent GPCRs awarded by National Institutes of Health 2006 - 2010
- Innovative Assays for Oncogenic Hedgehog Signaling awarded by National Institutes of Health 2006 - 2010
- Dopamine Receptors: Characterization And Regulation awarded by National Institutes of Health 1983 - 2008
- Molecular fingerprinting of GPCR ligands in Cancer awarded by National Institutes of Health 2004 - 2006
- Zeiss LSM510 META confocal-fluorescence spectroscopy awarded by National Institutes of Health 2003 - 2004
- Mechanisms of G Protein Coupled Receptor Regulation awarded by National Institutes of Health 1999 - 2004
- Mechanisms Of Beta2-Adrenergic Receptor Internalization awarded by National Institutes of Health 1996 - 1999
Publications & Artistic Works
Selected Publications
- Conference Papers
  - Mook, RA, Chen, M, Lu, J, Barak, LS, Lyerly, HK, and Chen, W. "Abstract 5681: Modulation of Wnt/β-catenin signaling by niclosamide and related derivatives." April 15, 2013. Full Text
  - Masri, B, Barak, LS, Bai, Y, Knibiehler, B, Caron, MG, and Audigier, Y. "Identification and pharmacological properties of an antagonist of apelin receptors." September 9, 2010. Full Text Link to Item
  - Exum, ST, Peppel, K, Barak, LS, Premont, RT, Zhang, LS, and Freedman, NJ. "Regulation of the platelet-derived growth factor receptor-beta by G protein-coupled receptor kinases in smooth muscle cells and fibroblasts: Evidence for kinase specificity." October 26, 2004. Link to Item
  - Zhang, J, Ferguson, SSG, Barak, LS, Aber, MJ, Giros, B, Lefkowitz, RJ, and Caron, MG. "Mini-Review - Molecular mechanisms of G protein-coupled receptor signaling: Role of G protein-coupled receptor kinases and arrestins in receptor desensitization and resensitization." 1997. Link to Item
- Journal Articles
  - Toth, K, Slosky, LM, Pack, TF, Urs, NM, Boone, P, Mao, L, Abraham, D, Caron, MG, and Barak, LS. "Ghrelin receptor antagonism of hyperlocomotion in cocaine-sensitized mice requires βarrestin-2." Synapse (New York, N.Y.) 72, no. 1 (January 2018). Full Text
  - Fakhouri, L, Cook, CD, Al-Huniti, MH, Console-Bram, LM, Hurst, DP, Spano, MBS, Nasrallah, DJ, Caron, MG, Barak, LS, Reggio, PH, Abood, ME, and Croatt, MP. "Design, synthesis and biological evaluation of GPR55 agonists." Bioorganic & Medicinal Chemistry 25, no. 16 (August 2017): 4355-4367. Full Text
  - Le Gonidec, S, Chaves-Almagro, C, Bai, Y, Kang, HJ, Smith, A, Wanecq, E, Huang, X-P, Prats, H, Knibiehler, B, Roth, BL, Barak, LS, Caron, MG, Valet, P, Audigier, Y, and Masri, B. "Protamine is an antagonist of apelin receptor, and its activity is reversed by heparin." Faseb Journal : Official Publication of the Federation of American Societies for Experimental Biology 31, no. 6 (June 2017): 2507-2519. Full Text
  - Snyder, JC, Rochelle, LK, Ray, C, Pack, TF, Bock, CB, Lubkov, V, Lyerly, HK, Waggoner, AS, Barak, LS, and Caron, MG. "Inhibiting clathrin-mediated endocytosis of the leucine-rich G protein-coupled receptor-5 diminishes cell fitness." The Journal of biological chemistry 292, no. 17 (April 2017): 7208-7222. Full Text
  - Mook, RA, Ren, X-R, Wang, J, Piao, H, Barak, LS, Kim Lyerly, H, and Chen, W. "Benzimidazole inhibitors from the Niclosamide chemotype inhibit Wnt/β-catenin signaling with selectivity over effects on ATP homeostasis." Bioorganic & medicinal chemistry 25, no. 6 (March 2017): 1804-1816. Full Text
  - Ray, C, Soderblom, EJ, Bai, Y, Carroll, FI, Caron, MG, and Barak, LS. "Probing the Allosteric Role of the α5 Subunit of α3β4α5 Nicotinic Acetylcholine Receptors by Functionally Selective Modulators and Ligands." Acs Chemical Biology 12, no. 3 (March 2017): 702-714. Full Text
  - Barak, LS, Bai, Y, Peterson, S, Evron, T, Urs, NM, Peddibhotla, S, Hedrick, MP, Hershberger, P, Maloney, PR, Chung, TDY, Rodriguiz, RM, Wetsel, WC, Thomas, JB, Hanson, GR, Pinkerton, AB, and Caron, MG. "ML314: A Biased Neurotensin Receptor Ligand for Methamphetamine Abuse." Acs Chemical Biology 11, no. 7 (July 2016): 1880-1890. Full Text
  - Meza-Aviña, ME, Lingerfelt, MA, Console-Bram, LM, Gamage, TF, Sharir, H, Gettys, KE, Hurst, DP, Kotsikorou, E, Shore, DM, Caron, MG, Rao, N, Barak, LS, Abood, ME, Reggio, PH, and Croatt, MP. "Design, synthesis, and analysis of antagonists of GPR55: Piperidine-substituted 1,3,4-oxadiazol-2-ones." Bioorganic & medicinal chemistry letters 26, no. 7 (April 2016): 1827-1830. Full Text
  - Snyder, JC, Pack, TF, Rochelle, LK, Chakraborty, SK, Zhang, M, Eaton, AW, Bai, Y, Ernst, LA, Barak, LS, Waggoner, AS, and Caron, MG. "A rapid and affordable screening platform for membrane protein trafficking." BMC biology 13 (December 17, 2015): 107-. Full Text
  - Ren, XR, Wang, J, Osada, T, Mook, RA, Morse, MA, Barak, LS, Lyerly, HK, and Chen, W. "Perhexiline promotes HER3 ablation through receptor internalization and inhibits tumor growth." Breast cancer research : BCR 17, no. 1 (December 2015): 528-.
  - Mook, RA, Wang, J, Ren, X-R, Chen, M, Spasojevic, I, Barak, LS, Lyerly, HK, and Chen, W. "Structure-activity studies of Wnt/β-catenin inhibition in the Niclosamide chemotype: Identification of derivatives with improved drug exposure." Bioorganic & Medicinal Chemistry 23, no. 17 (September 2015): 5829-5838. Full Text
  - Snyder, JC, Rochelle, LK, Marion, S, Lyerly, HK, Barak, LS, and Caron, MG. "Lgr4 and Lgr5 drive the formation of long actin-rich cytoneme-like membrane protrusions." Journal of Cell Science 128, no. 6 (March 2015): 1230-1240. Full Text
  - Ren, X-R, Wang, J, Osada, T, Mook, RA, Morse, MA, Barak, LS, Lyerly, HK, and Chen, W. "Perhexiline promotes HER3 ablation through receptor internalization and inhibits tumor growth." Breast cancer research : BCR 17 (February 15, 2015): 20-. Full Text
  - Burczyk, M, Burkhalter, MD, Blätte, T, Matysik, S, Caron, MG, Barak, LS, and Philipp, M. "Phenotypic regulation of the sphingosine 1-phosphate receptor miles apart by G protein-coupled receptor kinase 2." Biochemistry 54, no. 3 (January 15, 2015): 765-775. Full Text
  - Evron, T, Peterson, SM, Urs, NM, Bai, Y, Rochelle, LK, Caron, MG, and Barak, LS. "G Protein and β-arrestin signaling bias at the ghrelin receptor." The Journal of Biological Chemistry 289, no. 48 (November 2014): 33442-33455. Full Text
  - Tadokoro, T, Wang, Y, Barak, LS, Bai, Y, Randell, SH, and Hogan, BLM. "IL-6/STAT3 promotes regeneration of airway ciliated cells from basal stem cells." Proceedings of the National Academy of Sciences of the United States of America 111, no. 35 (September 2014): E3641-E3649. Full Text
  - Hershberger, PM, Hedrick, MP, Peddibhotla, S, Mangravita-Novo, A, Gosalia, P, Li, Y, Gray, W, Vicchiarelli, M, Smith, LH, Chung, TDY, Thomas, JB, Caron, MG, Pinkerton, AB, Barak, LS, and Roth, GP. "Imidazole-derived agonists for the neurotensin 1 receptor." Bioorganic and Medicinal Chemistry Letters 24, no. 1 (January 1, 2014): 262-267. Full Text
  - Snyder, JC, Rochelle, LK, Barak, LS, and Caron, MG. "Correction: The Stem Cell-Expressed Receptor Lgr5 Possesses Canonical and Functionally Active Molecular Determinants Critical to β-arrestin-2 Recruitment." PloS one 9, no. 1 (2014). Full Text
  - Kotsikorou, E, Sharir, H, Shore, DM, Hurst, DP, Lynch, DL, Madrigal, KE, Heynen-Genel, S, Milan, LB, Chung, TDY, Seltzman, HH, Bai, Y, Caron, MG, Barak, LS, Croatt, MP, Abood, ME, and Reggio, PH. "Identification of the GPR55 Antagonist Binding Site Using a Novel Set of High-Potency GPR55 Selective Ligands." Biochemistry 52, no. 52 (December 31, 2014): 9456-9469. Full Text
  - Kotsikorou, E, Sharir, H, Shore, DM, Hurst, DP, Lynch, DL, Madrigal, KE, Heynen-Genel, S, Milan, LB, Chung, TDY, Seltzman, HH, Bai, Y, Caron, MG, Barak, LS, Croatt, MP, Abood, ME, and Reggio, PH. "Identification of the GPR55 antagonist binding site using a novel set of high-potency GPR55 selective ligands." Biochemistry 52, no. 52 (December 17, 2013): 9456-9469. Full Text
  - Evron, T, Urs, NM, Sutton, L, Bai, Y, Caron, MG, and Barak, LS. "β-arrestin Regulation of Ghrelin Signaling in modulating Addictive Behavior." (December 1, 2013): 184-null. (Chapter) Full Text
  - Peddibhotla, S, Hedrick, MP, Hershberger, P, Maloney, PR, Li, Y, Milewski, M, Gosalia, P, Gray, W, Mehta, A, Sugarman, E, Hood, B, Suyama, E, Nguyen, K, Heynen-Genel, S, Vasile, S, Salaniwal, S, Stonich, D, Su, Y, Mangravita-Novo, A, Vicchiarelli, M, Roth, GP, Smith, LH, Chung, TDY, Hanson, GR, Thomas, JB, Caron, MG, Barak, LS, and Pinkerton, AB. "Discovery of ML314, a brain penetrant nonpeptidic β-arrestin biased agonist of the neurotensin NTR1 receptor." ACS Medicinal Chemistry Letters 4, no. 9 (September 12, 2013): 846-851. Full Text
  - Barak, LS, Bai, Y, Snyder, JC, Wang, J, Chen, W, and Caron, MG. "Triphenylmethane dye activation of beta-arrestin." Biochemistry 52, no. 32 (August 2013): 5403-5414. Full Text
  - Thakur, GA, Bajaj, S, Paronis, C, Peng, Y, Bowman, AL, Barak, LS, Caron, MG, Parrish, D, Deschamps, JR, and Makriyannis, A. "Novel adamantyl cannabinoids as CB1 receptor probes." Journal of Medicinal Chemistry 56, no. 10 (May 14, 2013): 3904-3921. Full Text
  - Dray, C, Sakar, Y, Vinel, C, Daviaud, D, Masri, B, Garrigues, L, Wanecq, E, Galvani, S, Negre-Salvayre, A, Barak, LS, Monsarrat, B, Burlet-Schiltz, O, Valet, P, Castan-Laurell, I, and Ducroc, R. "The intestinal glucose-apelin cycle controls carbohydrate absorption in mice." Gastroenterology 144, no. 4 (April 2013): 771-780. Full Text
  - Mook, RA, Chen, M, Lu, J, Barak, LS, Lyerly, HK, and Chen, W. "Small molecule modulators of Wnt/β-catenin signaling." Bioorg Med Chem Lett 23, no. 7 (April 1, 2013): 2187-2191. Full Text Link to Item
  - Snyder, JC, Rochelle, LK, Lyerly, HK, Caron, MG, and Barak, LS. "Constitutive internalization of the leucine-rich G protein-coupled receptor-5 (LGR5) to the trans-Golgi network." The Journal of Biological Chemistry 288, no. 15 (April 2013): 10286-10297. Full Text
  - Hershberger, PM, Hedrick, MP, Peddibhotla, S, Mangravita-Novo, A, Gosalia, P, Li, Y, Gray, W, Vicchiarelli, M, Smith, LH, Chung, TDY, Thomas, JB, Caron, MG, Pinkerton, AB, Barak, LS, and Roth, GP. "Imidazole-derived agonists for the neurotensin 1 receptor." Bioorganic and Medicinal Chemistry Letters (2013).
  - Lu, J, Chen, M, Ren, X-R, Wang, J, Lyerly, HK, Barak, L, and Chen, W. "Regulation of hedgehog signaling by Myc-interacting zinc finger protein 1, Miz1. (Published online)" PLoS One 8, no. 5 (2013): e63353-. Full Text Link to Item
  - Snyder, JC, Rochelle, LK, Barak, LS, and Caron, MG. "The stem cell-expressed receptor Lgr5 possesses canonical and functionally active molecular determinants critical to β-arrestin-2 recruitment. (Published online)" PLoS One 8, no. 12 (2013): e84476-. Full Text Link to Item
  - Wang, J, Mook, RA, Lu, J, Gooden, DM, Ribeiro, A, Guo, A, Barak, LS, Lyerly, HK, and Chen, W. "Identification of a novel Smoothened antagonist that potently suppresses Hedgehog signaling." Bioorg Med Chem 20, no. 22 (November 15, 2012): 6751-6757. Full Text Link to Item
  - Wang, J, Lu, J, Mook, RA, Zhang, M, Zhao, S, Barak, LS, Freedman, JH, Lyerly, HK, and Chen, W. "The insecticide synergist piperonyl butoxide inhibits hedgehog signaling: assessing chemical risks." Toxicological Sciences 128, no. 2 (August 2012): 517-523. Full Text
  - Ren, X-R, Wei, J, Lei, G, Wang, J, Lu, J, Xia, W, Spector, N, Barak, LS, Clay, TM, Osada, T, Hamilton, E, Blackwell, K, Hobeika, AC, Morse, MA, Lyerly, HK, and Chen, W. "Polyclonal HER2-specific antibodies induced by vaccination mediate receptor internalization and degradation in tumor cells. (Published online)" Breast Cancer Res 14, no. 3 (June 7, 2012): R89-. Full Text Link to Item
  - Frankowski, KJ, Hedrick, MP, Gosalia, P, Li, K, Shi, S, Whipple, D, Ghosh, P, Prisinzano, TE, Schoenen, FJ, Su, Y, Vasile, S, Sergienko, E, Gray, W, Hariharan, S, Milan, L, Heynen-Genel, S, Mangravita-Novo, A, Vicchiarelli, M, Smith, LH, Streicher, JM, Caron, MG, Barak, LS, Bohn, LM, Chung, TDY, and Aubé, J. "Discovery of Small Molecule Kappa Opioid Receptor Agonist and Antagonist Chemotypes through a HTS and Hit Refinement Strategy." Acs Chemical Neuroscience 3, no. 3 (March 2012): 221-236. Full Text
  - Barak, LS, and Peterson, S. "Modeling of bias for the analysis of receptor signaling in biochemical systems." Biochemistry 51, no. 6 (February 14, 2012): 1114-1125. Full Text Link to Item
  - Salahpour, A, Espinoza, S, Masri, B, Lam, V, Barak, LS, and Gainetdinov, RR. "BRET biosensors to study GPCR biology, pharmacology, and signal transduction. (Published online)" Front Endocrinol (Lausanne) 3 (2012): 105-. Full Text Link to Item
  - Espinoza, S, Salahpour, A, Masri, B, Sotnikova, TD, Messa, M, Barak, LS, Caron, MG, and Gainetdinov, RR. "Functional interaction between trace amine-associated receptor 1 and dopamine D2 receptor." Molecular Pharmacology 80, no. 3 (September 2011): 416-425. Full Text
  - Salahpour, A, and Barak, LS. "Visualizing receptor endocytosis and trafficking." Methods Mol Biol 756 (2011): 311-323. Full Text Link to Item
  - Wang, J, Barak, LS, Mook, RA, and Chen, W. "Glucocorticoid hedgehog agonists in neurogenesis." Vitam Horm 87 (2011): 207-215. (Review) Full Text Link to Item
  - Sotnikova, TD, Beaulieu, J-M, Espinoza, S, Masri, B, Zhang, X, Salahpour, A, Barak, LS, Caron, MG, and Gainetdinov, RR. "The dopamine metabolite 3-methoxytyramine is a neuromodulator. (Published online)" PLoS One 5, no. 10 (October 18, 2010): e13452-. Full Text Open Access Copy Link to Item
  - Zhao, P, Sharir, H, Kapur, A, Cowan, A, Geller, EB, Adler, MW, Seltzman, HH, Reggio, PH, Heynen-Genel, S, Sauer, M, Chung, TDY, Bai, Y, Chen, W, Caron, MG, Barak, LS, and Abood, ME. "Targeting of the orphan receptor GPR35 by pamoic acid: a potent activator of extracellular signal-regulated kinase and β-arrestin2 with antinociceptive activity." Mol Pharmacol 78, no. 4 (October 2010): 560-568. Full Text Link to Item
  - Chen, W, Chen, M, and Barak, LS. "Development of small molecules targeting the Wnt pathway for the treatment of colon cancer: a high-throughput screening approach." American Journal of Physiology. Gastrointestinal and Liver Physiology 299, no. 2 (August 2010): G293-G300. (Review) Full Text
  - Wang, J, Lu, J, Bond, MC, Chen, M, Ren, X-R, Lyerly, HK, Barak, LS, and Chen, W. "Identification of select glucocorticoids as Smoothened agonists: potential utility for regenerative medicine." Proc Natl Acad Sci U S A 107, no. 20 (May 18, 2010): 9323-9328. Full Text Open Access Copy Link to Item
  - Chen, M, Wang, J, Lu, J, Bond, MC, Ren, X-R, Lyerly, HK, Barak, LS, and Chen, W. "The anti-helminthic niclosamide inhibits Wnt/Frizzled1 signaling." Biochemistry 48, no. 43 (November 2009): 10267-10274. Full Text
  - Kapur, A, Zhao, P, Sharir, H, Bai, Y, Caron, MG, Barak, LS, and Abood, ME. "Atypical responsiveness of the orphan receptor GPR55 to cannabinoid ligands." The Journal of Biological Chemistry 284, no. 43 (October 2009): 29817-29827. Full Text
  - Philipp, M, Fralish, GB, Meloni, AR, Chen, W, MacInnes, AW, Barak, LS, and Caron, MG. "Smoothened signaling in vertebrates is facilitated by a G protein-coupled receptor kinase." Molecular Biology of the Cell 19, no. 12 (December 2008): 5478-5489. Full Text
  - Barak, LS, Salahpour, A, Zhang, X, Masri, B, Sotnikova, TD, Ramsey, AJ, Violin, JD, Lefkowitz, RJ, Caron, MG, and Gainetdinov, RR. "Pharmacological characterization of membrane-expressed human trace amine-associated receptor 1 (TAAR1) by a bioluminescence resonance energy transfer cAMP biosensor." Molecular Pharmacology 74, no. 3 (September 2008): 585-594. Full Text
  - Ryu, H, Walker, JKL, Kim, S, Koo, N, Barak, LS, Noguchi, T, Kang, BY, and Kim, K-M. "Regulation of M2-type pyruvate kinase mediated by the high-affinity IgE receptors is required for mast cell degranulation." Br J Pharmacol 154, no. 5 (July 2008): 1035-1046. Full Text Link to Item
  - Shenoy, SK, Barak, LS, Xiao, K, Ahn, S, Berthouze, M, Shukla, AK, Luttrell, LM, and Lefkowitz, RJ. "Ubiquitination of beta-arrestin links seven-transmembrane receptor endocytosis and ERK activation." The Journal of Biological Chemistry 282, no. 40 (October 2007): 29549-29562. Full Text
  - Marion, S, Fralish, GB, Laporte, S, Caron, MG, and Barak, LS. "N-terminal tyrosine modulation of the endocytic adaptor function of the beta-arrestins." The Journal of Biological Chemistry 282, no. 26 (June 2007): 18937-18944. Full Text
  - Marion, S, Oakley, RH, Kim, K-M, Caron, MG, and Barak, LS. "A beta-arrestin binding determinant common to the second intracellular loops of rhodopsin family G protein-coupled receptors." The Journal of Biological Chemistry 281, no. 5 (February 2006): 2932-2938. Full Text
  - Barak, LS, Gilchrist, J, Becker, JM, and Kim, K-M. "Relationship between the G protein signaling and homologous desensitization of G protein-coupled receptors." Biochem Biophys Res Commun 339, no. 2 (January 13, 2006): 695-700. Full Text Link to Item
  - Sotnikova, TD, Beaulieu, J-M, Barak, LS, Wetsel, WC, Caron, MG, and Gainetdinov, RR. "Dopamine-independent locomotor actions of amphetamines in a novel acute mouse model of Parkinson disease." Plos Biology 3, no. 8 (August 2, 2005): e271-null. Full Text
  - Kim, K-M, Gainetdinov, RR, Laporte, SA, Caron, MG, and Barak, LS. "G protein-coupled receptor kinase regulates dopamine D3 receptor signaling by modulating the stability of a receptor-filamin-beta-arrestin complex. A case of autoreceptor regulation." The Journal of Biological Chemistry 280, no. 13 (April 2005): 12774-12780. Full Text
  - Kim, KM, Gainetdinov, RR, Laporte, SA, Caron, MG, and Barak, LS. "G protein-coupled receptor kinase regulates dopamine D-3 receptor signaling by modulating the stability of a receptor-filamin-beta-arrestin complex - A case of autoreceptor regulation." JOURNAL OF BIOLOGICAL CHEMISTRY 280, no. 13 (April 1, 2005): 12774-12780. Full Text Link to Item
  - Chen, W, Ren, X-R, Nelson, CD, Barak, LS, Chen, JK, Beachy, PA, de Sauvage, F, and Lefkowitz, RJ. "Activity-dependent internalization of smoothened mediated by beta-arrestin 2 and GRK2." Science (New York, N.Y.) 306, no. 5705 (December 2004): 2257-2260. Full Text
  - Wilbanks, AM, Fralish, GB, Kirby, ML, Barak, LS, Li, Y-X, and Caron, MG. "Beta-arrestin 2 regulates zebrafish development through the hedgehog signaling pathway." Science (New York, N.Y.) 306, no. 5705 (December 2004): 2264-2267. Full Text
  - Hildreth, KL, Wu, J-H, Barak, LS, Exum, ST, Kim, LK, Peppel, K, and Freedman, NJ. "Phosphorylation of the platelet-derived growth factor receptor-beta by G protein-coupled receptor kinase-2 reduces receptor signaling and interaction with the Na(+)/H(+) exchanger regulatory factor." The Journal of Biological Chemistry 279, no. 40 (October 2004): 41775-41782. Full Text
  - Bohn, LM, Dykstra, LA, Lefkowitz, RJ, Caron, MG, and Barak, LS. "Relative opioid efficacy is determined by the complements of the G protein-coupled receptor desensitization machinery." Molecular Pharmacology 66, no. 1 (July 2004): 106-112. Full Text
  - Johnson, EC, Bohn, LM, Barak, LS, Birse, RT, Nässel, DR, Caron, MG, and Taghert, PH. "Identification of Drosophila neuropeptide receptors by G protein-coupled receptors-beta-arrestin2 interactions." The Journal of Biological Chemistry 278, no. 52 (December 2003): 52172-52178. Full Text
  - Bektas, M, Barak, LS, Jolly, PS, Liu, H, Lynch, KR, Lacana, E, Suhr, K-B, Milstien, S, and Spiegel, S. "The G protein-coupled receptor GPR4 suppresses ERK activation in a ligand-independent manner." Biochemistry 42, no. 42 (October 28, 2003): 12181-12191. Full Text Link to Item
  - Chen, W, ten Berge, D, Brown, J, Ahn, S, Hu, LA, Miller, WE, Caron, MG, Barak, LS, Nusse, R, and Lefkowitz, RJ. "Dishevelled 2 recruits beta-arrestin 2 to mediate Wnt5A-stimulated endocytosis of Frizzled 4." Science (New York, N.Y.) 301, no. 5638 (September 2003): 1391-1394. Full Text
  - Barak, LS, Oakley, RH, and Shetzline, MA. "G protein-coupled receptor desensitization as a measure of signaling: modeling of arrestin recruitment to activated CCK-B receptors." Assay and Drug Development Technologies 1, no. 3 (June 2003): 409-424. Full Text
  - Barak, LS, Wilbanks, AM, and Caron, MG. "Constitutive desensitization: a new paradigm for g protein-coupled receptor regulation." Assay Drug Dev Technol 1, no. 2 (April 2003): 339-346. (Review) Full Text Link to Item
  - Richardson, RM, Marjoram, RJ, Barak, LS, and Snyderman, R. "Role of the cytoplasmic tails of CXCR1 and CXCR2 in mediating leukocyte migration, activation, and regulation." J Immunol 170, no. 6 (March 15, 2003): 2904-2911. Link to Item
  - Richardson, MD, Balius, AM, Yamaguchi, K, Freilich, ER, Barak, LS, and Kwatra, MM. "Human substance P receptor lacking the C-terminal domain remains competent to desensitize and internalize." Journal of Neurochemistry 84, no. 4 (February 2003): 854-863. Full Text
  - Wilbanks, AM, Laporte, SA, Bohn, LM, Barak, LS, and Caron, MG. "Apparent loss-of-function mutant GPCRs revealed as constitutively desensitized receptors." Biochemistry 41, no. 40 (October 2002): 11981-11989. Full Text
  - Naga Prasad, SV, Laporte, SA, Chamberlain, D, Caron, MG, Barak, L, and Rockman, HA. "Phosphoinositide 3-kinase regulates beta2-adrenergic receptor endocytosis by AP-2 recruitment to the receptor/beta-arrestin complex." The Journal of Cell Biology 158, no. 3 (August 5, 2002): 563-575. Full Text
  - Kim, Y-M, Barak, LS, Caron, MG, and Benovic, JL. "Regulation of arrestin-3 phosphorylation by casein kinase II." J Biol Chem 277, no. 19 (May 10, 2002): 16837-16846. Full Text Link to Item
  - Shetzline, MA, Oakley, RH, Caron, MG, and Barak, LS. "Quantitative evaluation of CCK-B receptor regulation using an arrestin/green fluorescent protein biosensor: A novel technology for the determination of serum gastrin bioactivity." GASTROENTEROLOGY 122, no. 4 (April 2002): A523-A523. Link to Item
  - Prasad, SVN, Barak, LS, Woo, KVV, and Rockman, HA. "Identification of the amino acid domain involved in the beta ARK/PI3K interaction and its role in beta AR sequestration." CIRCULATION 104, no. 17 (October 23, 2001): 144-144. Link to Item
  - Kim, KM, Valenzano, KJ, Robinson, SR, Yao, WD, Barak, LS, and Caron, MG. "Differential regulation of the dopamine D2 and D3 receptors by G protein-coupled receptor kinases and beta-arrestins." The Journal of Biological Chemistry 276, no. 40 (October 2001): 37409-37414. Full Text
  - Naga Prasad, SV, Barak, LS, Rapacciuolo, A, Caron, MG, and Rockman, HA. "Agonist-dependent recruitment of phosphoinositide 3-kinase to the membrane by beta-adrenergic receptor kinase 1. A role in receptor sequestration." The Journal of Biological Chemistry 276, no. 22 (June 2001): 18953-18959. Full Text
  - Oakley, RH, Laporte, SA, Holt, JA, Barak, LS, and Caron, MG. "Molecular determinants underlying the formation of stable intracellular G protein-coupled receptor-beta-arrestin complexes after receptor endocytosis*." The Journal of Biological Chemistry 276, no. 22 (June 2001): 19452-19460. Full Text
  - Hobson, JP, Rosenfeldt, HM, Barak, LS, Olivera, A, Poulton, S, Caron, MG, Milstien, S, and Spiegel, S. "Role of the sphingosine-1-phosphate receptor EDG-1 in PDGF-induced cell motility." Science (New York, N.Y.) 291, no. 5509 (March 2001): 1800-1803. Full Text
  - Barak, LS, Oakley, RH, Laporte, SA, and Caron, MG. "Constitutive arrestin-mediated desensitization of a human vasopressin receptor mutant associated with nephrogenic diabetes insipidus." Proceedings of the National Academy of Sciences of the United States of America 98, no. 1 (January 2001): 93-98. Full Text
  - Prasad, SVN, Barak, LS, Rapacciuolo, A, Caron, MG, and Rockman, HA. "beta-Adrenergic receptor kinase 1 mediated phosphoinositide-3-kinase translocation: A process linked to receptor internalization." CIRCULATION 102, no. 18 (October 31, 2000): 222-222. Link to Item
  - Laporte, SA, Oakley, RH, Holt, JA, Barak, LS, and Caron, MG. "The interaction of beta-arrestin with the AP-2 adaptor is required for the clustering of beta 2-adrenergic receptor into clathrin-coated pits." J Biol Chem 275, no. 30 (July 28, 2000): 23120-23126. Full Text Link to Item
  - Oakley, RH, Laporte, SA, Holt, JA, Caron, MG, and Barak, LS. "Differential affinities of visual arrestin, beta arrestin1, and beta arrestin2 for G protein-coupled receptors delineate two major classes of receptors." The Journal of Biological Chemistry 275, no. 22 (June 2000): 17201-17210. Full Text
  - Carman, CV, Barak, LS, Chen, C, Liu-Chen, LY, Onorato, JJ, Kennedy, SP, Caron, MG, and Benovic, JL. "Mutational analysis of Gbetagamma and phospholipid interaction with G protein-coupled receptor kinase 2." The Journal of Biological Chemistry 275, no. 14 (April 2000): 10443-10452. Full Text
  - Carman, CV, Barak, LS, Chen, C, Liu-Chen, L-Y, Onorato, JJ, Kennedy, SP, Caron, MG, and Benovic, JL. "Mutational analysis of Gβγ and phospholipid interaction with kinase G protein-coupled receptor 2." Journal of Biological Chemistry 275, no. 14 (2000): 10443-10452. Full Text
  - Jones, SR, Joseph, JD, Barak, LS, Caron, MG, and Wightman, RM. "Dopamine neuronal transport kinetics and effects of amphetamine." J Neurochem 73, no. 6 (December 1999): 2406-2414. Link to Item
  - Oakley, RH, Laporte, SA, Holt, JA, Barak, LS, and Caron, MG. "Association of beta-arrestin with G protein-coupled receptors during clathrin-mediated endocytosis dictates the profile of receptor resensitization." J Biol Chem 274, no. 45 (November 5, 1999): 32248-32257. Link to Item
  - Walker, JK, Premont, RT, Barak, LS, Caron, MG, and Shetzline, MA. "Properties of secretin receptor internalization differ from those of the beta(2)-adrenergic receptor." J Biol Chem 274, no. 44 (October 29, 1999): 31515-31523. Link to Item
  - Zhang, J, Barak, LS, Anborgh, PH, Laporte, SA, Caron, MG, and Ferguson, SS. "Cellular trafficking of G protein-coupled receptor/beta-arrestin endocytic complexes." J Biol Chem 274, no. 16 (April 16, 1999): 10999-11006. Link to Item
  - Laporte, SA, Oakley, RH, Zhang, J, Holt, JA, Ferguson, SSG, Caron, MG, and Barak, LS. "The β2-adrenergic receptor/βarrestin complex recruits the clathrin adaptor AP-2 during endocytosis." Proceedings of the National Academy of Sciences of the United States of America 96, no. 7 (March 30, 1999): 3712-3717. Full Text
  - Barak, LS, Warabi, K, Feng, X, Caron, MG, and Kwatra, MM. "Real-time visualization of the cellular redistribution of G protein-coupled receptor kinase 2 and beta-arrestin 2 during homologous desensitization of the substance P receptor." The Journal of Biological Chemistry 274, no. 11 (March 1999): 7565-7569. Full Text
  - Laporte, SA, Oakley, RH, Zhang, J, Holt, JA, Ferguson, SS, Caron, MG, and Barak, LS. "The beta2-adrenergic receptor/betaarrestin complex recruits the clathrin adaptor AP-2 during endocytosis." Proceedings of the National Academy of Sciences of the United States of America 96, no. 7 (March 1999): 3712-3717. Full Text
  - Mhaouty-Kodja, S, Barak, LS, Scheer, A, Abuin, L, Diviani, D, Caron, MG, and Cotecchia, S. "Constitutively active alpha-1b adrenergic receptor mutants display different phosphorylation and internalization features." Molecular Pharmacology 55, no. 2 (February 1999): 339-347. Full Text
  - Barak, LS, Zhang, J, Ferguson, SS, Laporte, SA, and Caron, MG. "Signaling, desensitization, and trafficking of G protein-coupled receptors revealed by green fluorescent protein conjugates." Methods in Enzymology 302 (January 1999): 153-171. Full Text
  - Laporte, SA, Oakley, RH, Zhang, J, Holt, JA, Ferguson, SSG, Caron, MG, and Barak, LS. "The β₂-adrenergic receptor/βarrestin complex recruits the clathrin adaptor AP-2 during endocytosis." Proceedings of the National Academy of Sciences of the United States of America 96, no. 7 (1999): 3712-3717. Full Text
  - Zhang, J, Ferguson, SS, Law, PY, Barak, LS, and Caron, MG. "Agonist-specific regulation of delta-opioid receptor trafficking by G protein-coupled receptor kinase and beta-arrestin." J Recept Signal Transduct Res 19, no. 1-4 (January 1999): 301-313. Full Text Link to Item
  - Zhang, J, Ferguson, SS, Barak, LS, Bodduluri, SR, Laporte, SA, Law, PY, and Caron, MG. "Role for G protein-coupled receptor kinase in agonist-specific regulation of mu-opioid receptor responsiveness." Proceedings of the National Academy of Sciences of the United States of America 95, no. 12 (June 1998): 7157-7162. Full Text
  - Pitcher, JA, Hall, RA, Daaka, Y, Zhang, J, Ferguson, SS, Hester, S, Miller, S, Caron, MG, Lefkowitz, RJ, and Barak, LS. "The G protein-coupled receptor kinase 2 is a microtubule-associated protein kinase that phosphorylates tubulin." The Journal of Biological Chemistry 273, no. 20 (May 1998): 12316-12324. Full Text
  - Hall, RA, Premont, RT, Chow, CW, Blitzer, JT, Pitcher, JA, Claing, A, Stoffel, RH, Barak, LS, Shenolikar, S, Weinman, EJ, Grinstein, S, and Lefkowitz, RJ. "The β2-adrenergic receptor interacts with the Na(+/H+)-exchanger regulatory factor to control Na(+/H+) exchange." Nature 392, no. 6676 (April 9, 1998): 626-630. Full Text
  - Feng, X, Zhang, J, Barak, LS, Meyer, T, Caron, MG, and Hannun, YA. "Visualization of dynamic trafficking of a protein kinase C betaII/green fluorescent protein conjugate reveals differences in G protein-coupled receptor activation and desensitization." The Journal of Biological Chemistry 273, no. 17 (April 1998): 10755-10762. Full Text
  - Hall, RA, Premont, RT, Chow, CW, Blitzer, JT, Pitcher, JA, Claing, A, Stoffel, RH, Barak, LS, Shenolikar, S, Weinman, EJ, Grinstein, S, and Lefkowitz, RJ. "The beta2-adrenergic receptor interacts with the Na+/H+-exchanger regulatory factor to control Na+/H+ exchange." Nature 392, no. 6676 (April 1998): 626-630. Full Text
  - Ferguson, SS, Zhang, J, Barak, LS, and Caron, MG. "Role of beta-arrestins in the intracellular trafficking of G-protein-coupled receptors." Adv Pharmacol 42 (1998): 420-424. Link to Item
  - Ferguson, SS, Zhang, J, Barak, LS, and Caron, MG. "Molecular mechanisms of G protein-coupled receptor desensitization and resensitization." Life Sci 62, no. 17-18 (1998): 1561-1565. (Review) Link to Item
  - Barak, LS, Zhang, J, Ferguson, SSG, Miller, S, Hester, S, and Caron, MG. "Association of beta adrenergic receptor kinase 1 with tubulin and mitochondrial membranes in living cells." MOLECULAR BIOLOGY OF THE CELL 8 (November 1997): 265-265. Link to Item
  - Zhang, J, Barak, LS, Winkler, KE, Caron, MG, and Ferguson, SS. "A central role for beta-arrestins and clathrin-coated vesicle-mediated endocytosis in beta2-adrenergic receptor resensitization. Differential regulation of receptor resensitization in two distinct cell types." J Biol Chem 272, no. 43 (October 24, 1997): 27005-27014. Link to Item
  - Barak, LS, Ferguson, SS, Zhang, J, and Caron, MG. "A beta-arrestin/green fluorescent protein biosensor for detecting G protein-coupled receptor activation." The Journal of Biological Chemistry 272, no. 44 (October 1997): 27497-27500. Full Text
  - Ménard, L, Ferguson, SS, Zhang, J, Lin, FT, Lefkowitz, RJ, Caron, MG, and Barak, LS. "Synergistic regulation of beta2-adrenergic receptor sequestration: intracellular complement of beta-adrenergic receptor kinase and beta-arrestin determine kinetics of internalization." Molecular Pharmacology 51, no. 5 (May 1997): 800-808. Full Text
  - Barak, LS, Ferguson, SS, Zhang, J, Martenson, C, Meyer, T, and Caron, MG. "Internal trafficking and surface mobility of a functionally intact beta2-adrenergic receptor-green fluorescent protein conjugate." Molecular Pharmacology 51, no. 2 (February 1997): 177-184. Full Text
  - Barak, LS, Ferguson, SSG, Zhang, J, and Caron, MG. "A β-arrestin/green fluorescent protein biosensor for detecting G protein-coupled receptor activation." Journal of Biological Chemistry 272, no. 44 (1997): 27497-27500. Full Text
  - Ferguson, SSG, Zhang, J, Barak, LS, and Caron, MG. "Pleiotropic role for GRKs and β-arrestins in receptor regulation." News in Physiological Sciences 12, no. 4 (1997): 145-151.
  - Ferguson, SSG, Zhang, J, Barak, LS, and Circ, MG. "Role of β-Arrestins in the IntracelIular Trafficking of G-Protein-Coupled Receptors." Advances in Pharmacology 42, no. C (1997): 420-424. Full Text
  - Zhang, J, Ferguson, SS, Barak, LS, Aber, MJ, Giros, B, Lefkowitz, RJ, and Caron, MG. "Molecular mechanisms of G protein-coupled receptor signaling: role of G protein-coupled receptor kinases and arrestins in receptor desensitization and resensitization." Receptors & Channels 5, no. 3-4 (January 1997): 193-199. (Review)
  - Barak, LS, Zhang, J, Ferguson, SSG, and Caron, MG. "Characterization of a green fluorescent protein conjugated Beta(2)-adrenergic receptor." MOLECULAR BIOLOGY OF THE CELL 7 (December 1996): 2484-2484. Link to Item
  - Caron, MG, Zhang, J, Barak, LS, and Ferguson, SSG. "Molecular determinants of G protein-coupled receptor internalization: A mechanism of resensitization." MOLECULAR BIOLOGY OF THE CELL 7 (December 1996): 973-973. Link to Item
  - Zhang, J, Ferguson, SSG, Barak, LS, and Caron, MG. "Dynamin and beta-arrestin reveal distinct mechanisms for G protein-coupled receptor endocytosis." MOLECULAR BIOLOGY OF THE CELL 7 (December 1996): 485-485. Link to Item
  - Ferguson, SS, Zhang, J, Barak, LS, and Caron, MG. "G-protein-coupled receptor kinases and arrestins: regulators of G-protein-coupled receptor sequestration." Biochem Soc Trans 24, no. 4 (November 1996): 953-959. (Review) Link to Item
  - Ferguson, SS, Barak, LS, Zhang, J, and Caron, MG. "G-protein-coupled receptor regulation: role of G-protein-coupled receptor kinases and arrestins." Canadian Journal of Physiology and Pharmacology 74, no. 10 (October 1996): 1095-1110. (Review) Full Text
  - Zhang, J, Ferguson, SS, Barak, LS, Ménard, L, and Caron, MG. "Dynamin and beta-arrestin reveal distinct mechanisms for G protein-coupled receptor internalization." J Biol Chem 271, no. 31 (August 2, 1996): 18302-18305. Link to Item
  - Ménard, L, Ferguson, SS, Barak, LS, Bertrand, L, Premont, RT, Colapietro, AM, Lefkowitz, RJ, and Caron, MG. "Members of the G protein-coupled receptor kinase family that phosphorylate the beta2-adrenergic receptor facilitate sequestration." Biochemistry 35, no. 13 (April 2, 1996): 4155-4160. Full Text Link to Item
  - Ferguson, SS, Downey, WE, Colapietro, AM, Barak, LS, Ménard, L, and Caron, MG. "Role of beta-arrestin in mediating agonist-promoted G protein-coupled receptor internalization." Science (New York, N.Y.) 271, no. 5247 (January 1996): 363-366. Full Text
  - Barak, LS, Ménard, L, Ferguson, SS, Colapietro, AM, and Caron, MG. "The conserved seven-transmembrane sequence NP(X)2,3Y of the G-protein-coupled receptor superfamily regulates multiple properties of the beta 2-adrenergic receptor." Biochemistry 34, no. 47 (November 1995): 15407-15414. Full Text
  - Ferguson, SS, Ménard, L, Barak, LS, Koch, WJ, Colapietro, AM, and Caron, MG. "Role of phosphorylation in agonist-promoted beta 2-adrenergic receptor sequestration. Rescue of a sequestration-defective mutant receptor by beta ARK1." J Biol Chem 270, no. 42 (October 20, 1995): 24782-24789. Link to Item
  - FERGUSON, SSG, MENARD, L, BARAK, LS, COLAPIETRO, AM, KOCH, WJ, and CARON, MG. "A ROLE OF PHOSPHORYLATION IN AGONIST-PROMOTED SEQUESTRATION IMPLICATED BY THE RESCUE OF A SEQUESTRATION-DEFECTIVE BETA(2)-ADRENERGIC RECEPTOR MUTANT BY BETA-ARK1." FASEB JOURNAL 9, no. 6 (April 24, 1995): A1412-A1412. Link to Item
  - Barak, LS, and Caron, MG. "Modeling of sequestration and down regulation in cells containing beta2-adrenergic receptors." J Recept Signal Transduct Res 15, no. 1-4 (January 1995): 677-690. Full Text Link to Item
  - Barak, LS, Tiberi, M, Freedman, NJ, Kwatra, MM, Lefkowitz, RJ, and Caron, MG. "A highly conserved tyrosine residue in G protein-coupled receptors is required for agonist-mediated beta 2-adrenergic receptor sequestration." J Biol Chem 269, no. 4 (January 28, 1994): 2790-2795. Link to Item
  - CARON, MG, TIBERI, M, and BARAK, LS. "CATECHOLAMINE RECEPTORS - MOLECULAR CHARACTERIZATION AND PHYSIOLOGICAL IMPLICATIONS." NEUROPSYCHOPHARMACOLOGY 9, no. 2 (September 1993): S35-S36. Link to Item
  - BARAK, LS, KWATRA, MM, LEFKOWITZ, RJ, and CARON, MG. "A HIGHLY CONSERVED MOTIF IN THE 7 TRANSMEMBRANE REGION OF THE BETA-2 ADRENERGIC-RECEPTOR DIRECTS RECEPTOR SEQUESTRATION." CLINICAL RESEARCH 41, no. 2 (April 1993): A258-A258. Link to Item
  - Gieron, MA, Barak, LS, and Estrada, J. "Severe encephalopathy associated with ifosfamide administration in two children with metastatic tumors." J Neurooncol 6, no. 1 (1988): 29-30. Link to Item
  - Tank, DW, Fredericks, WJ, Barak, LS, and Webb, WW. "Electric field-induced redistribution and postfield relaxation of low density lipoprotein receptors on cultured human fibroblasts." The Journal of Cell Biology 101, no. 1 (July 1985): 148-157. Full Text
  - Barak, LS, and Webb, WW. "Diffusion of low density lipoprotein-receptor complex on human fibroblasts." J Cell Biol 95, no. 3 (December 1982): 846-852. Link to Item
  - Barak, LS, and Webb, WW. "Fluorescent low density lipoprotein for observation of dynamics of individual receptor complexes on cultured human fibroblasts." The Journal of Cell Biology 90, no. 3 (September 1981): 595-604. Full Text
  - Carley, WW, Barak, LS, and Webb, WW. "F-actin aggregates in transformed cells." J Cell Biol 90, no. 3 (September 1981): 797-802. Link to Item
  - Barak, LS, Nothnagel, EA, DeMarco, EF, and Webb, WW. "Differential staining of actin in metaphase spindles with 7-nitrobenz-2-oxa-1,3-diazole-phallacidin and fluorescent DNase: is actin involved in chromosomal movement?." Proc Natl Acad Sci U S A 78, no. 5 (May 1981): 3034-3038. Link to Item
  - Barak, LS, Yocum, RR, and Webb, WW. "In vivo staining of cytoskeletal actin by autointernalization of nontoxic concentrations of nitrobenzoxadiazole-phallacidin." J Cell Biol 89, no. 2 (May 1981): 368-372. Link to Item
  - Nothnagel, EA, Barak, LS, Sanger, JW, and Webb, WW. "Fluorescence studies on modes of cytochalasin B and phallotoxin action on cytoplasmic streaming in Chara." The Journal of Cell Biology 88, no. 2 (February 1981): 364-372. Full Text
  - BARAK, L. "Differential staining of actin in metaphase spindle with 7-nitrobenz-2-oxa-1,3-diazole-phallacidin and fluorescent DNase: Is actin involved in chromosomal movement?." Proc Natl Acad Sci USA 78 (1981): 3034-3038. Full Text
  - BARAK, LS, and WEBB, WW. "MOLECULAR-MOTION OF INDIVIDUAL LDL MOLECULES ON CELL-MEMBRANES." BIOPHYSICAL JOURNAL 33, no. 2 (1981): A74-A74. Link to Item
  - Barak, LS, and Yocum, RR. "7-Nitrobenz-2-oxa-1,3-diazole (NBD)--phallacidin: synthesis of a fluorescent actin probe." Anal Biochem 110, no. 1 (January 1, 1981): 31-38. Link to Item
  - WEBB, WW, BARAK, LS, TANK, DW, and WU, ES. "DIFFUSIBILITY OF CELL-SURFACE PROTEINS-RELEASE OF CONSTRAINTS." JOURNAL OF CELL BIOLOGY 91, no. 2 (1981): A107-A107. Link to Item
  - Webb, WW, Barak, LS, Tank, DW, and Wu, ES. "Molecular mobility on the cell surface." Biochem Soc Symp , no. 46 (1981): 191-205. (Review) Link to Item
  - Barak, LS, Yocum, RR, Nothnagel, EA, and Webb, WW. "Fluorescence staining of the actin cytoskeleton in living cells with 7-nitrobenz-2-oxa-1,3-diazole-phallacidin." Proc Natl Acad Sci U S A 77, no. 2 (February 1980): 980-984. Link to Item
  - BARAK, LS, and WEBB, WW. "INVIVO LABELING OF CYTOSKELETAL ACTIN BY NBD-PHALLACIDIN." JOURNAL OF CELL BIOLOGY 87, no. 2 (1980): A214-A214. Link to Item
  - BARAK, LS. "CORRECTION." PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES 77, no. 6 (1980): 3747-3748. Link to Item
  - Barak, LS, Yocum, RR, Nothnagel, EA, and Webb, WW. "Fluorescence staining of the actin cytoskeleton in living cells with 7-nitrobenz-2-oxa-1,3-diazole-phallacidin." Proceedings of the National Academy of Sciences of the United States of America 77, no. 2 II (1980): 980-984.
  - Schlessinger, J, Barak, LS, Hammes, GG, Yamada, KM, Pastan, I, Webb, WW, and Elson, EL. "Mobility and distribution of a cell surface glycoprotein and its interaction with other membrane components." Proc Natl Acad Sci U S A 74, no. 7 (July 1977): 2909-2913. Link to Item
  - Fahey, PF, Koppel, DE, Barak, LS, Wolf, DE, Elson, EL, and Webb, WW. "Lateral diffusion in planar lipid bilayers." Science (New York, N.Y.) 195, no. 4275 (January 1977): 305-306. Full Text

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