Scholars@Duke
Lakshmi I. Katakam

Lakshmi I. Katakam

Associate Professor of Pediatrics
Pediatrics, Neonatology
lakshmi.katakam@duke.edu
Box 3179 Med Ctr, Durham, NC 27710
Dept of Pediatrics, Durham, NC 27710

Scholarly Works

Variation of caffeine use in late preterm infants in U.S. NICUs over time: A 12-year cohort study.

Journal article J Perinatol · June 22, 2026 OBJECTIVE: Describe caffeine use in late preterm infants (LPIs) in neonatal intensive care units (NICUs) over time METHODS: Cohort study of infants born 34-36 weeks gestation discharged from Pediatrix Medical Group NICUs from 2011-2022. RESULTS: Of 233,804 ... Full text Link to item Cite

The impact of an obstetric substance use screening and biologic testing protocol on neonatal drug testing.

Journal article J Perinatol · April 2026 OBJECTIVE: Substance use during pregnancy may affect fetal development and have implications for newborn, childhood, and life-long health. While standardized maternal screening protocols may reduce testing disparities, there are limited data describing the ... Full text Link to item Cite

Leadership Challenges in Neonatal Services during the COVID-19 Pandemic.

Journal article Am J Perinatol · October 2025 This study aimed to identify key challenges, barriers, personal experiences, coping mechanisms, and lessons learned by neonatal health care leaders during the COVID-19 pandemic, because they are not well documented.Voluntary, anonymous, online survey of le ... Full text Link to item Cite

Gentamicin Pharmacokinetics in Neonates Undergoing Therapeutic Hypothermia for Hypoxic Ischemic Encephalopathy.

Journal article Paediatr Drugs · January 2025 PURPOSE: The purpose of this study was to review the pharmacokinetic profile of gentamicin among neonates with hypoxic ischemic encephalopathy (HIE) undergoing therapeutic hypothermia (TH) treatment. METHODS: This was a retrospective study of neonates with ... Full text Link to item Cite

Decreasing Blood Transfusions in Premature Infants Through Quality Improvement.

Journal article Pediatrics · August 1, 2024 BACKGROUND AND OBJECTIVES: Packed red blood cell transfusions (pRBCT) in preterm infants have been associated with significant morbidity. Although infants <26 weeks' gestational age typically require several pRBCT, preterm infants born between 26 and 34 we ... Full text Link to item Cite

Updated Perspectives on the Diagnosis and Management of Neonatal Invasive Candidiasis

Journal article Research and Reports in Neonatology · November 2023 Full text Cite

Ventilation-Induced Lung Injury (VILI) in Neonates: Evidence-Based Concepts and Lung-Protective Strategies.

Journal article J Clin Med · January 22, 2022 Supportive care with mechanical ventilation continues to be an essential strategy for managing severe neonatal respiratory failure; however, it is well known to cause and accentuate neonatal lung injury. The pathogenesis of ventilator-induced lung injury ( ... Full text Link to item Cite

Complications of respiratory support

Book section · January 1, 2022 Full text Cite

Lowest PaCO2 on the first day of life predicts mortality and morbidity among infants with congenital diaphragmatic hernia.

Journal article J Perinatol · February 2019 OBJECTIVE: To evaluate the association between hypercarbia in the first 24 h of life and clinical outcomes in infants with congenital diaphragmatic hernia (CDH). STUDY DESIGN: Retrospective review of patients entered into the CDHSG registry between 2007-20 ... Full text Link to item Cite

Mask versus Prongs for Nasal Continuous Positive Airway Pressure in Preterm Infants: A Systematic Review and Meta-Analysis.

Journal article Neonatology · 2019 Nasal continuous positive airway pressure (NCPAP) is an effective method of respiratory support for preterm infants. Nasal masks and binasal prongs are two interfaces available to deliver NCPAP, and it is unclear if one is superior to the other. We conduct ... Full text Link to item Cite

Identifying a quality improvement project.

Journal article J Perinatol · October 2017 An important step on the roadmap to a successful quality improvement (QI) project is careful selection of topics and aims to be addressed by QI projects. Using information from a variety of data monitoring systems as well as individual events and experienc ... Full text Link to item Cite

Predicting neonatal intubation competency in trainees.

Journal article Pediatrics · May 2015 BACKGROUND AND OBJECTIVES: Pediatric residency training programs are graduating residents who are not competent in neonatal intubation, a vital skill needed for any pediatrician involved in delivery room resuscitations. However, a precise definition of com ... Full text Link to item Cite

Speaking up and sharing information improves trainee neonatal resuscitations.

Journal article J Patient Saf · December 2012 OBJECTIVES: To identify teamwork behaviors associated with improving efficiency and quality of simulated resuscitation training. METHODS: Secondary analysis of a randomized controlled trial of trainees undergoing neonatal resuscitation training was perform ... Full text Link to item Cite

Treatment of patent ductus arteriosus with bidirectional flow in neonates.

Journal article Early Hum Dev · May 2011 BACKGROUND: Patent ductus arteriosus is a common occurrence among prematurely born neonates and is believed to play a role in the development of other complications of prematurity including intraventricular hemorrhage, bronchopulmonary dysplasia, and necro ... Full text Link to item Cite

Recombinant activated factor VIIa treatment for refractory hemorrhage in infants.

Journal article J Perinatol · March 2011 OBJECTIVE: Report clinical response to recombinant factor VIIa in a cohort of critically ill infants. STUDY DESIGN: We identified all infants who received factor VIIa in the Duke Neonatal Intensive Care Unit between January 2005 and July 2008. Hematologica ... Full text Link to item Cite

Safety and effectiveness of indomethacin versus ibuprofen for treatment of patent ductus arteriosus.

Journal article Am J Perinatol · May 2010 We compared the rates of medical closure of patent ductus arteriosus (PDA) and complications (renal dysfunction, necrotizing enterocolitis, spontaneous intestinal perforation, and intraventricular hemorrhage) between infants treated with indomethacin and i ... Full text Link to item Cite