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Lars Johannes L Grimm

Associate Professor of Radiology
Radiology, Breast Imaging
Dept of Radiology, Box 3808, Durham, NC 27710

Featured Works


Bias in Radiology Resident Selection: Do We Discriminate Against the Obese and Unattractive?

Journal article Acad Med · November 2019 Featured Publication PURPOSE: To evaluate for appearance-based discrimination in the selection of radiology residents. METHOD: A deception study simulating the resident selection process examined the impact of attractiveness and obesity on resident selection. Seventy-four core ... Full text Link to item Cite

Growth Dynamics of Mammographic Calcifications: Differentiating Ductal Carcinoma in Situ from Benign Breast Disease.

Journal article Radiology · July 2019 Featured Publication Background Most ductal carcinoma in situ (DCIS) lesions are first detected on screening mammograms as calcifications. However, false-positive biopsy rates for calcifications range from 30% to 87%. Improved methods to differentiate benign from malignant cal ... Full text Link to item Cite

Breast MRI radiogenomics: Current status and research implications.

Journal article J Magn Reson Imaging · June 2016 Featured Publication Breast magnetic resonance imaging (MRI) radiogenomics is an emerging area of research that has the potential to directly influence clinical practice. Clinical MRI scanners today are capable of providing excellent temporal and spatial resolution, which allo ... Full text Link to item Cite

Men (and Women) in Academic Radiology: How Can We Reduce the Gender Discrepancy?

Journal article AJR Am J Roentgenol · April 2016 Featured Publication OBJECTIVE: There is a chronic gender imbalance in academic radiology departments, which could limit our field's ability to foster creative, productive, and innovative environments. We recently reviewed 51 major academic radiology faculty rosters and discov ... Full text Link to item Cite

Benefits and Harms of Breast Cancer Screening: A Systematic Review.

Journal article JAMA · October 20, 2015 Featured Publication IMPORTANCE: Patients need to consider both benefits and harms of breast cancer screening. OBJECTIVE: To systematically synthesize available evidence on the association of mammographic screening and clinical breast examination (CBE) at different ages and in ... Full text Link to item Cite

Computational approach to radiogenomics of breast cancer: Luminal A and luminal B molecular subtypes are associated with imaging features on routine breast MRI extracted using computer vision algorithms.

Journal article J Magn Reson Imaging · October 2015 Featured Publication PURPOSE: To identify associations between semiautomatically extracted MRI features and breast cancer molecular subtypes. METHODS: We analyzed routine clinical pre-operative breast MRIs from 275 breast cancer patients at a single institution in this retrosp ... Full text Link to item Cite

Abbreviated screening protocol for breast MRI: a feasibility study.

Journal article Acad Radiol · September 2015 Featured Publication RATIONALE AND OBJECTIVES: To compare the performance of two shortened breast magnetic resonance imaging (MRI) protocols to a standard MRI protocol for breast cancer screening. MATERIALS AND METHODS: In this Health Insurance Portability and Accountability A ... Full text Link to item Cite

Can breast cancer molecular subtype help to select patients for preoperative MR imaging?

Journal article Radiology · February 2015 Featured Publication PURPOSE: To assess whether breast cancer molecular subtype classified by surrogate markers can be used to predict the extent of clinically relevant disease with preoperative breast magnetic resonance (MR) imaging. MATERIALS AND METHODS: In this HIPAA-compl ... Full text Link to item Cite

Radiogenomic analysis of breast cancer: luminal B molecular subtype is associated with enhancement dynamics at MR imaging.

Journal article Radiology · November 2014 Featured Publication PURPOSE: To investigate associations between breast cancer molecular subtype and semiautomatically extracted magnetic resonance (MR) imaging features. MATERIALS AND METHODS: Imaging and genomic data from the Cancer Genome Atlas and the Cancer Imaging Archi ... Full text Link to item Cite