Research Interests
I am a clinical researcher with interest in the care of children, adolescents, and young adults with solid tumors. More specifically, I am interested in developing new therapies for patients with recurrent sarcoma.
Selected Grants
JZP712-101: A phase 1/2, open-label study to evaluate the safety, tolerability, pharmacokinetics (PK), recommended phase 2 dose (RP2D), and efficacy
Clinical TrialPrincipal Investigator · Awarded by Jazz Pharmaceuticals · 2024 - 2027VAL-10-001: Pilot Pharmacokinetic Study of VAL-413 in Patients with Recurrent Pediatric Solid Tumors
Clinical TrialPrincipal Investigator · Awarded by Valent Technologies, LLC · 2022 - 2026Offering Hope to Pediatric Cancer Patients Through Research and Psychosocial Support
Institutional SupportPrincipal Investigator · Awarded by Hyundai Hope on Wheels · 2025 - 2025Improving Symptom Management for Adolescents and Young Adults with Advanced Cancer: Development and Pilot Testing of a Novel Intervention
ResearchCo Investigator · Awarded by National Institutes of Health · 2022 - 2025NCI Community Oncology Research Program (NCORP) Research Base Grant
ResearchPrincipal Investigator · Awarded by Public Health Institute · 2021 - 2025ACNS1831
Clinical TrialPrincipal Investigator · Awarded by Public Health Institute · 2022 - 2025Neuroblastoma Maintenance Therapy Trial Using Difluoromethylornithine (DFMO)
ResearchPrincipal Investigator · Awarded by Atrium Health · 2021 - 2025Evolutionary Inspired Therapy for Newly Diagnosed, Metastatic, Fusion Positive Rhabdomyosarcoma
Clinical TrialPrincipal Investigator · Awarded by H. Lee Moffitt Cancer Center & Research Institute · 2020 - 2025NPFC Sunshine Project
ResearchPrincipal Investigator · Awarded by National Pediatric Cancer Foundation, Inc. · 2023 - 2025Cookies for Kids' Cancer Supplmental PCR
ResearchPrincipal Investigator · Awarded by Children's Oncology Group · 2022 - 2025Project: EveryChild (APEC1481)
ResearchPrincipal Investigator · Awarded by Children's Oncology Group · 2022 - 2025St. Baldrick's Foundation Supplement PCR
ResearchPrincipal Investigator · Awarded by Children's Oncology Group · 2022 - 2025A Phase Ib/II Study to Evaluate the Safety, Feasibility and Efficacy of Nivolumab or Nivolumab in Combination with 5-Azacytidine in Patients with Recurrent, Resectable Osteosarcoma
Clinical TrialPrincipal Investigator · Awarded by H. Lee Moffitt Cancer Center & Research Institute · 2021 - 2025Blood Based Biomarkers for Minimal Residual Disease Detection in Pediatric Sarcomas
Clinical TrialPrincipal Investigator · Awarded by H. Lee Moffitt Cancer Center & Research Institute · 2020 - 2025Longitudinal, multimodal assessment of neuropsychological functioning in children diagnosed with high-risk lymphoblastic leukemia (HR-ALL): Using early changes to predict later impairment (ALTE07C1)
ResearchPrincipal Investigator · Awarded by Children's Hospital of Philadelphia · 2022 - 2025BIQSFP Year 10_PCR ACNS1831 AR66358
ResearchPrincipal Investigator · Awarded by Public Health Institute · 2022 - 2025Per Case Reimbursement : NIH National Clinical Trials Network (NCTN)
Clinical TrialPrincipal Investigator · Awarded by Public Health Institute · 2021 - 2025Workload Intensity NIH National Clinical Trials Network (NCTN)
Clinical TrialPrincipal Investigator · Awarded by Public Health Institute · 2021 - 2025Project: One Time EOY, Integrated BIQSFP AAML1031- Echocardiogram Reports and Images
ResearchPrincipal Investigator · Awarded by Children's Hospital of Philadelphia · 2019 - 2025Pilot Investigation of Stool Glucuronidase Activity and Microbial Diversity
Clinical TrialPrincipal Investigator · Awarded by Symberix · 2024 - 2024Hyundai Hope on Wheels Impact Grant
Institutional SupportPrincipal Investigator · Awarded by Hyundai Hope on Wheels · 2024 - 2024Modeling tumor heterogeneity and therapy resistance in osteosarcoma using patient-derived organoids
ResearchPrincipal Investigator · Awarded by Hyundai Hope on Wheels · 2021 - 2024APAL2020SC (AR61731)
ResearchPrincipal Investigator · Awarded by Public Health Institute · 2022 - 2024PEPCTN_NonCoreStudyStartup_WLI
ResearchPrincipal Investigator · Awarded by Public Health Institute · 2021 - 2024PEPCTN_PCR
ResearchPrincipal Investigator · Awarded by Public Health Institute · 2021 - 2024NIH COG Pediatric Early Phase Clinical Trial Network Grant (PEP-CTN)
ResearchPrincipal Investigator · Awarded by Children's Hospital of Philadelphia · 2020 - 2023NPFC Sunshine Project
ResearchPrincipal Investigator · Awarded by National Pediatric Cancer Foundation, Inc. · 2020 - 2023A Multi-Center Phase III, Randomized, Open-Label Trial of Vigil (bi-shRNAfurin and GMCSF Augmented Autologous Tumor Cell Immunotherapy) in combination with Irinotecan and Temozolomide as a Second-Line Regimen for Ewing's Sarcoma (CL-PTL-130)
Clinical TrialPrincipal Investigator · Awarded by Gradalis, Inc. · 2019 - 2023NCI Community Oncology Research Program (NCORP) Research Base Grant
ResearchPrincipal Investigator · Awarded by Children's Hospital of Philadelphia · 2014 - 2022Implementing Family Psychosocial Risk Screening for Pediatric Health Equity
ResearchPrincipal Investigator · Awarded by Nemours · 2021 - 2021Per Case Reimbursement : NIH National Clinical Trials Network (NCTN)
Clinical TrialPrincipal Investigator · Awarded by Children's Hospital of Philadelphia · 2014 - 2021Workload Intensity NIH National Clinical Trials Network (NCTN)
Clinical TrialPrincipal Investigator · Awarded by Children's Hospital of Philadelphia · 2014 - 2021AALL1131 Supplemental PCR
ResearchPrincipal Investigator · Awarded by Children's Hospital of Philadelphia · 2020 - 2021Specimen Banking Supplements
ResearchPrincipal Investigator · Awarded by Children's Hospital of Philadelphia · 2020 - 2021External Relationships
- Jazz Pharmaceuticals
This faculty member (or a member of their immediate family) has reported outside activities with the companies, institutions, or organizations listed above. This information is available to institutional leadership and, when appropriate, management plans are in place to address potential conflicts of interest.