Scholars@Duke

• Recognition
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  Awards & Honors

  • Finalist. Northwestern Cardiovascular Young Investigators Forum. October 20, 2018
• Publications & Artistic Works
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  Selected Publications

  • Academic Articles

    • DeFilippis, Ersilia M., Khadijah Breathett, Elena M. Donald, Shunichi Nakagawa, Koji Takeda, Hiroo Takayama, Lauren K. Truby, et al. “Psychosocial Risk and Its Association With Outcomes in Continuous-Flow Left Ventricular Assist Device Patients.” Circulation. Heart Failure 13, no. 9 (September 8, 2020): e006910. https://doi.org/10.1161/circheartfailure.120.006910.
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    • Abdulrahim, Jawan W., Lydia Coulter Kwee, Fawaz Alenezi, Albert Y. Sun, Aris Baras, Teminioluwa A. Ajayi, Ricardo Henao, et al. “Identification of Undetected Monogenic Cardiovascular Disorders.” J Am Coll Cardiol 76, no. 7 (August 18, 2020): 797–808. https://doi.org/10.1016/j.jacc.2020.06.037.
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    • Truby, Lauren K., and Joseph G. Rogers. “Advanced Heart Failure: Epidemiology, Diagnosis, and Therapeutic Approaches.” Jacc Heart Fail 8, no. 7 (July 2020): 523–36. https://doi.org/10.1016/j.jchf.2020.01.014.
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    • Clemons, Autumn M., Raul J. Flores, Raia Blum, Brian Wayda, Danielle L. Brunjes, Marlena Habal, Raymond C. Givens, et al. “Effect of Socioeconomic Status on Patients Supported with Contemporary Left Ventricular Assist Devices.” Asaio Journal (American Society for Artificial Internal Organs : 1992) 66, no. 4 (April 2020): 373–80. https://doi.org/10.1097/mat.0000000000001009.
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    • Jaiswal, Abhishek, Lauren K. Truby, Astha Chichra, Rashmi Jain, Leann Myers, Nirav Patel, and Veli K. Topkara. “Impact of Obesity on Ventricular Assist Device Outcomes.” Journal of Cardiac Failure 26, no. 4 (April 2020): 287–97. https://doi.org/10.1016/j.cardfail.2019.10.001.
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    • Truby, Lauren K., Christopher O’Connor, Mona Fiuzat, Amanda Stebbins, Adrian Coles, Chetan B. Patel, Bradi Granger, et al. “Sex Differences in Quality of Life and Clinical Outcomes in Patients With Advanced Heart Failure: Insights From the PAL-HF Trial.” Circ Heart Fail 13, no. 4 (April 2020): e006134. https://doi.org/10.1161/CIRCHEARTFAILURE.119.006134.
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    • Truby, Lauren K., Jaya Batra, Douglas L. Jennings, Koji Takeda, Ersilia M. DeFilippis, Hiroo Takayama, Yoshifumi Naka, Maryjane A. Farr, and Veli K. Topkara. “Impact of Induction Immunosuppression on Post-Transplant Outcomes of Patients Bridged with Contemporary Left Ventricular Assist Devices.” Asaio Journal (American Society for Artificial Internal Organs : 1992) 66, no. 3 (March 2020): 261–67. https://doi.org/10.1097/mat.0000000000001119.
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    • Farr, Maryjane, Lauren K. Truby, Joel Lindower, Ulrich Jorde, Samantha Taylor, Leway Chen, Alan Gass, et al. “Potential for donation after circulatory death heart transplantation in the United States: Retrospective analysis of a limited UNOS dataset.” American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20, no. 2 (February 2020): 525–29. https://doi.org/10.1111/ajt.15597.
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    • Truby, Lauren K., and Veli K. Topkara. “Response by Truby and Topkara to Letter Regarding Article, "Impact of Bridge to Transplantation With Continuous-Flow Left Ventricular Assist Devices on Posttransplantation Mortality: A Propensity-Matched Analysis of the United Network of Organ Sharing Database".” Circulation 140, no. 25 (December 16, 2019): e942–43. https://doi.org/10.1161/circulationaha.119.044323.
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    • Truby, Lauren K., Maryjane A. Farr, A Reshad Garan, Raymond Givens, Susan W. Restaino, Farhana Latif, Hiroo Takayama, Yoshifumi Naka, Koji Takeda, and Veli K. Topkara. “Impact of Bridge to Transplantation With Continuous-Flow Left Ventricular Assist Devices on Posttransplantation Mortality.” Circulation 140, no. 6 (August 2019): 459–69. https://doi.org/10.1161/circulationaha.118.036932.
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    • Truby, Lauren K., Scott DeRoo, Jessica Spellman, Douglas L. Jennings, Koji Takeda, Barry Fine, Susan Restaino, and Maryjane Farr. “Management of primary graft failure after heart transplantation: Preoperative risks, perioperative events, and postoperative decisions.” Clinical Transplantation 33, no. 6 (June 2019): e13557. https://doi.org/10.1111/ctr.13557.
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    • Akanni, Olutosin J., Koji Takeda, Lauren K. Truby, Paul A. Kurlansky, Codruta Chiuzan, Jiho Han, Veli K. Topkara, et al. “EC-VAD: Combined Use of Extracorporeal Membrane Oxygenation and Percutaneous Microaxial Pump Left Ventricular Assist Device.” Asaio Journal (American Society for Artificial Internal Organs : 1992) 65, no. 3 (March 2019): 219–26. https://doi.org/10.1097/mat.0000000000000804.
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    • DeFilippis, Ersilia M., Lauren K. Truby, A Reshad Garan, Raymond C. Givens, Koji Takeda, Hiroo Takayama, Yoshifumi Naka, Jennifer H. Haythe, Maryjane A. Farr, and Veli K. Topkara. “Sex-Related Differences in Use and Outcomes of Left Ventricular Assist Devices as Bridge to Transplantation.” Jacc. Heart Failure 7, no. 3 (March 2019): 250–57. https://doi.org/10.1016/j.jchf.2019.01.008.
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    • Truby, Lauren K., Lakshmi Sridharan, Raul J. Flores, A Reshad Garan, Douglas Jennings, Melana Yuzefpolskaya, Koji Takeda, et al. “Red Cell Distribution Width Predicts 90 Day Mortality in Continuous-Flow Left Ventricular Assist Device Patients.” Asaio Journal (American Society for Artificial Internal Organs : 1992) 65, no. 3 (March 2019): 233–40. https://doi.org/10.1097/mat.0000000000000803.
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    • Truby, Lauren K., Koji Takeda, Veli K. Topkara, Hiroo Takayama, A Reshad Garan, Melana Yuzefpolskaya, Paolo Colombo, Yoshifumi Naka, and Maryjane Farr. “Risk of severe primary graft dysfunction in patients bridged to heart transplantation with continuous-flow left ventricular assist devices.” The Journal of Heart and Lung Transplantation : The Official Publication of the International Society for Heart Transplantation 37, no. 12 (December 2018): 1433–42. https://doi.org/10.1016/j.healun.2018.07.013.
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    • Truby, Lauren K., A Reshad Garan, Raymond C. Givens, Brian Wayda, Koji Takeda, Melana Yuzefpolskaya, Paolo C. Colombo, Yoshifumi Naka, Hiroo Takayama, and Veli K. Topkara. “Aortic Insufficiency During Contemporary Left Ventricular Assist Device Support: Analysis of the INTERMACS Registry.” Jacc. Heart Failure 6, no. 11 (November 2018): 951–60. https://doi.org/10.1016/j.jchf.2018.07.012.
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    • Habal, Marlena V., Lauren Truby, Masahiko Ando, Hirohisa Ikegami, Arthur R. Garan, Veli K. Topkara, Paolo Colombo, et al. “VA-ECMO for cardiogenic shock in the contemporary era of heart transplantation: Which patients should be urgently transplanted?” Clinical Transplantation 32, no. 9 (September 2018): e13356. https://doi.org/10.1111/ctr.13356.
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    • Kochav, Stephanie Meller, Raul J. Flores, Lauren K. Truby, and Veli K. Topkara. “Prognostic Impact of Pulmonary Artery Pulsatility Index (PAPi) in Patients With Advanced Heart Failure: Insights From the ESCAPE Trial.” Journal of Cardiac Failure 24, no. 7 (July 2018): 453–59. https://doi.org/10.1016/j.cardfail.2018.03.008.
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    • Truby, Lauren K., A Reshad Garan, Raymond C. Givens, Koji Takeda, Hiroo Takayama, Pauline N. Trinh, Melana Yuzefpolskaya, et al. “Ventricular Assist Device Utilization in Heart Transplant Candidates: Nationwide Variability and Impact on Waitlist Outcomes.” Circulation. Heart Failure 11, no. 4 (April 2018): e004586. https://doi.org/10.1161/circheartfailure.117.004586.
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    • Sridharan, Lakshmi, Brian Wayda, Lauren K. Truby, Farhana Latif, Susan Restaino, Koji Takeda, Hiroo Takayama, et al. “Mechanical Circulatory Support Device Utilization and Heart Transplant Waitlist Outcomes in Patients With Restrictive and Hypertrophic Cardiomyopathy.” Circulation. Heart Failure 11, no. 3 (March 2018): e004665. https://doi.org/10.1161/circheartfailure.117.004665.
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    • Truby, Lauren K., Koji Takeda, Maryjane Farr, James Beck, Melana Yuzefpolskaya, Paolo C. Colombo, Veli K. Topkara, Donna Mancini, Yoshifumi Naka, and Hiroo Takayama. “Incidence and Impact of On-Cardiopulmonary Bypass Vasoplegia During Heart Transplantation.” Asaio Journal (American Society for Artificial Internal Organs : 1992) 64, no. 1 (January 2018): 43–51. https://doi.org/10.1097/mat.0000000000000623.
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    • Fujita, Kevin, Koji Takeda, Boyangzi Li, Christine Mauro, Paul Kurlansky, Sowmyashree Sreekanth, Jiho Han, et al. “Combined Therapy of Ventricular Assist Device and Membrane Oxygenator for Profound Acute Cardiopulmonary Failure.” Asaio Journal (American Society for Artificial Internal Organs : 1992) 63, no. 6 (November 2017): 713–19. https://doi.org/10.1097/mat.0000000000000563.
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    • Wright, Matthew, Koji Takeda, Christine Mauro, Douglas Jennings, Paul Kurlansky, Jiho Han, Lauren Truby, et al. “Dose-dependent association between amiodarone and severe primary graft dysfunction in orthotopic heart transplantation.” The Journal of Heart and Lung Transplantation : The Official Publication of the International Society for Heart Transplantation 36, no. 11 (November 2017): 1226–33. https://doi.org/10.1016/j.healun.2017.05.025.
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    • Abadeer, Andrew I., Paul Kurlansky, Codruta Chiuzan, Lauren Truby, Jai Radhakrishnan, Reshad Garan, Veli Topkara, et al. “Importance of stratifying acute kidney injury in cardiogenic shock resuscitated with mechanical circulatory support therapy.” The Journal of Thoracic and Cardiovascular Surgery 154, no. 3 (September 2017): 856-864.e4. https://doi.org/10.1016/j.jtcvs.2017.04.042.
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    • Truby, Lauren K., Koji Takeda, Christine Mauro, Melana Yuzefpolskaya, Arthur R. Garan, Ajay J. Kirtane, Veli K. Topkara, et al. “Incidence and Implications of Left Ventricular Distention During Venoarterial Extracorporeal Membrane Oxygenation Support.” Asaio Journal (American Society for Artificial Internal Organs : 1992) 63, no. 3 (May 2017): 257–65. https://doi.org/10.1097/mat.0000000000000553.
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    • Truby, Lauren K., and Veli K. Topkara. “Angiopoietin-2: marker or mediator of angiogenesis in continuous-flow left ventricular assist device patients?” Journal of Thoracic Disease 8, no. 11 (November 2016): 3042–45. https://doi.org/10.21037/jtd.2016.11.04.
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    • Truby, Lauren, and Hiroo Takayama. “Reply to Spiliopoulos et al.” European Journal of Cardio Thoracic Surgery : Official Journal of the European Association for Cardio Thoracic Surgery 49, no. 4 (April 2016): 1299. https://doi.org/10.1093/ejcts/ezv330.
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    • Han, Jiho, Koji Takeda, Hiroo Takayama, Paul A. Kurlansky, Christine M. Mauro, Paolo C. Colombo, Melana Yuzefpolskaya, et al. “Durability and clinical impact of tricuspid valve procedures in patients receiving a continuous-flow left ventricular assist device.” The Journal of Thoracic and Cardiovascular Surgery 151, no. 2 (February 2016): 520-7.e1. https://doi.org/10.1016/j.jtcvs.2015.09.082.
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    • Truby, Lauren, Yoshifumi Naka, Bindu Kalesan, Takeyoshi Ota, Ajay J. Kirtane, Susheel Kodali, Natasha Nikic, et al. “Important role of mechanical circulatory support in acute myocardial infarction complicated by cardiogenic shock.” European Journal of Cardio Thoracic Surgery : Official Journal of the European Association for Cardio Thoracic Surgery 48, no. 2 (August 2015): 322–28. https://doi.org/10.1093/ejcts/ezu478.
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    • Truby, Lauren, Lily Mundy, Bindu Kalesan, Ajay Kirtane, Paolo C. Colombo, Koji Takeda, Shinichi Fukuhara, Yoshifumi Naka, and Hiroo Takayama. “Contemporary Outcomes of Venoarterial Extracorporeal Membrane Oxygenation for Refractory Cardiogenic Shock at a Large Tertiary Care Center.” Asaio Journal (American Society for Artificial Internal Organs : 1992) 61, no. 4 (July 2015): 403–9. https://doi.org/10.1097/mat.0000000000000225.
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    • Takayama, Hiroo, Elissa Landes, Lauren Truby, Kevin Fujita, Ajay J. Kirtane, Linda Mongero, Melana Yuzefpolskaya, et al. “Feasibility of smaller arterial cannulas in venoarterial extracorporeal membrane oxygenation.” The Journal of Thoracic and Cardiovascular Surgery 149, no. 5 (May 2015): 1428–33. https://doi.org/10.1016/j.jtcvs.2015.01.042.
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    • Takayama, Hiroo, Lori Soni, Bindu Kalesan, Lauren K. Truby, Takeyoshi Ota, Sophia Cedola, Zain Khalpey, et al. “Bridge-to-decision therapy with a continuous-flow external ventricular assist device in refractory cardiogenic shock of various causes.” Circulation. Heart Failure 7, no. 5 (September 2014): 799–806. https://doi.org/10.1161/circheartfailure.113.000271.
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    • Takayama, Hiroo, Lauren Truby, Michael Koekort, Nir Uriel, Paolo Colombo, Donna M. Mancini, Ulrich P. Jorde, and Yoshifumi Naka. “Clinical outcome of mechanical circulatory support for refractory cardiogenic shock in the current era.” The Journal of Heart and Lung Transplantation : The Official Publication of the International Society for Heart Transplantation 32, no. 1 (January 2013): 106–11. https://doi.org/10.1016/j.healun.2012.10.005.
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  • Conference Papers

    • Batra, J., D. Marshall, D. Jennings, L. Truby, E. DeFilippis, A. Malick, C. Butler, et al. “Elevated Serum C-reactive Protein (CRP) Level Predicts Increased Post-Implant Mortality in Patients Undergoing HeartMate 3 LVAD Implantation.” In The Journal of Heart and Lung Transplantation : The Official Publication of the International Society for Heart Transplantation, 39:S431–32, 2020. https://doi.org/10.1016/j.healun.2020.01.228.
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    • Batra, J., L. Truby, R. Garan, J. Haythe, E. Lin, K. Axsom, M. Yuzefpolskaya, et al. “C-reactive Protein Levels Predict Right Ventricular Failure and Mortality in Patients Undergoing Continuous-Flow Left Ventricular Assist Device Assist Device Implantation: An INTERMACS Analysis.” In The Journal of Heart and Lung Transplantation : The Official Publication of the International Society for Heart Transplantation, 39:S433, 2020. https://doi.org/10.1016/j.healun.2020.01.231.
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    • Buchan, T. A., Y. Moayedi, L. K. Truby, J. D. Posada, H. J. Ross, A. C. Alba, and F. Foroutan. “Incidence and Impact of Primary Graft Dysfunction in Adult Heart Transplant Recipients: A Systematic Review and Meta-Analysis.” In The Journal of Heart and Lung Transplantation : The Official Publication of the International Society for Heart Transplantation, 39:S144, 2020. https://doi.org/10.1016/j.healun.2020.01.1066.
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    • DeFilippis, E., J. Haythe, D. Marshall, E. Lin, K. Axsom, L. Truby, M. Yuzefpolskaya, et al. “Sex Differences in Characteristics and Outcomes Following HeartMate 3 Left Ventricular Assist Device Implantation.” In The Journal of Heart and Lung Transplantation : The Official Publication of the International Society for Heart Transplantation, 39:S337, 2020. https://doi.org/10.1016/j.healun.2020.01.371.
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    • Jain, R., M. Habal, S. Restaino, F. Latif, L. Truby, K. Clerkin, J. Raikhelkar, et al. “De-Novo Human Leukocyte Antigen Allosensitization on HeartMate 3 versus HeartMate II Left Ventricular Assist Device Recipients.” In The Journal of Heart and Lung Transplantation : The Official Publication of the International Society for Heart Transplantation, 39:S16, 2020. https://doi.org/10.1016/j.healun.2020.01.1139.
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    • Jennings, D. L., L. Truby, J. Fried, K. Clerkin, J. Griffin, J. Raikhelkar, K. Axsom, et al. “Impact of Heart Failure Drug Therapy on GI Bleeding Rates in LVAD Recipients: An INTERMACS Analysis.” In The Journal of Heart and Lung Transplantation : The Official Publication of the International Society for Heart Transplantation, 39:S26, 2020. https://doi.org/10.1016/j.healun.2020.01.1165.
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    • Marshall, D., A. Malick, L. Truby, C. Butler, J. Griffin, K. Clerkin, J. Fried, et al. “Pulmonary Artery Pulsatility Index (PAPi) is a Predictor of Right Ventricular Assist Device (RVAD) Use Following HeartMate 3 LVAD Implantation.” In The Journal of Heart and Lung Transplantation : The Official Publication of the International Society for Heart Transplantation, 39:S408, 2020. https://doi.org/10.1016/j.healun.2020.01.165.
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    • Marshall, D., E. DeFilippis, L. Truby, A. Malick, C. Butler, J. Griffin, K. Clerkin, et al. “Increased Right Ventricular Assist Device (RVAD) Utilization in Patients with HeartMate 3 Left Ventricular Assist Device (LVAD) in the Post-Approval Era.” In The Journal of Heart and Lung Transplantation : The Official Publication of the International Society for Heart Transplantation, 39:S431, 2020. https://doi.org/10.1016/j.healun.2020.01.226.
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    • Marshall, D., L. Truby, E. DeFilippis, A. Malick, C. Butler, A. Masoumi, J. Haythe, et al. “HeartMate II Risk Score (HMRS) and MELD-Xi Scores Do Not Predict Mortality in HeartMate 3 LVAD Patients.” In The Journal of Heart and Lung Transplantation : The Official Publication of the International Society for Heart Transplantation, 39:S432–33, 2020. https://doi.org/10.1016/j.healun.2020.01.230.
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    • Truby, L. K., A. D. Devore, S. D. Russell, J. N. Schroeder, C. B. Patel, J. G. Rogers, and R. Agarwal. “Predictors and Outcomes of Hemodynamic and Functional LVAD Non-Responders: An Analysis of the INTERMACS Registry.” In The Journal of Heart and Lung Transplantation : The Official Publication of the International Society for Heart Transplantation, 39:S39, 2020. https://doi.org/10.1016/j.healun.2020.01.1199.
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    • Truby, L. K., M. Farr, E. Defillipis, K. Takeda, H. Takayama, P. C. Colombo, M. Yuzefpolskaya, et al. “Utilization of Mechanical Circulatory Support Devices and Impact on Outcomes in the New Heart Allocation System: An Analysis of the UNOS Registry.” In The Journal of Heart and Lung Transplantation : The Official Publication of the International Society for Heart Transplantation, 39:S172, 2020. https://doi.org/10.1016/j.healun.2020.01.739.
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    • Truby, L. K., R. Agarwal, E. J. Stohr, K. Takeda, H. Takayama, Y. Naka, N. Uriel, and V. K. Topkara. “Impact of Pulse Pressure on Hemocompatibility Related Adverse Events during Support with Continuous Flow Left Ventricular Assist Devices: An Analysis of the INTERMACS Registry.” In The Journal of Heart and Lung Transplantation : The Official Publication of the International Society for Heart Transplantation, 39:S97, 2020. https://doi.org/10.1016/j.healun.2020.01.944.
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