ConferenceAmerican Journal of Respiratory and Critical Care Medicine · May 1, 2026
AbstractRationaleThe impact of initiating oxygen on health-related quality of life (HRQL) in patients with idiopathic pulmonary ...
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ConferenceAmerican Journal of Respiratory and Critical Care Medicine · May 1, 2025
AbstractRationale: Pulmonary fibrosis is associated with symptoms such as dyspnea and fatigue that may affect individuals’ ability to work. We assessed workplace productivity loss among patients with prog ...
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ConferenceAmerican Journal of Respiratory and Critical Care Medicine · May 1, 2025
AbstractRationale: The representativeness of patients who participate in clinical trials for the broader community of patients with IPF is uncertain. We examined associations between sociodemographic and ...
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ConferenceAmerican Journal of Respiratory and Critical Care Medicine · May 1, 2025
AbstractRationale: Respiratory hospitalizations are a significant cause of morbidity and mortality in individuals with idiopathic pulmonary fibrosis (IPF). We hypothesized that higher acute exposure to pa ...
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ConferenceAmerican Journal of Respiratory and Critical Care Medicine · May 1, 2025
AbstractRationale: Primary ciliary dyskinesia (PCD) is a heterogeneous, rare genetic disorder characterized by dysfunctional motile cilia. PCD pulmonary manifestations include impaired airway mucociliary ...
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ConferenceTransplant Direct · February 2024
BACKGROUND: Pulmonary embolism (PE) is a rare yet serious postoperative complication for lung transplant recipients (LTRs). The association between timing and severity of PE and the development of chronic allograft lung dysfunction (CLAD) has not been desc ...
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ConferenceProceedings of Machine Learning Research · January 1, 2022
The approaches by which the machine learning and clinical research communities utilize real world data (RWD), including data captured in the electronic health record (EHR), vary dramatically. While clinical researchers cautiously use RWD for clinical inves ...
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ConferenceRespir Med · 2021
BACKGROUND: Few data are available on the extent to which clinical practice is aligned with international guidelines for the management of idiopathic pulmonary fibrosis (IPF). We investigated the extent to which management guidelines for IPF have been impl ...
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ConferenceJ Heart Lung Transplant · October 2020
BACKGROUND: Post-transplant lymphoproliferative disorder (PTLD) is a life-threatening complication following lung transplant. We studied incidence and risk factors for PTLD in adult lung transplant recipients (LTRs) using the International Society for Hear ...
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ConferenceThe Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · April 1, 2020
PURPOSE: Highly sensitized lung transplant candidates undergo transplant at a significantly lower rate than unsensitized candidates. We conducted a survey to understand the approach to waitlist and peri-operative management of these candidates across progr ...
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ConferenceThe Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · April 1, 2020
PURPOSE: CLAD, mainly manifest as bronchiolitis obliterans syndrome (BOS), is the leading cause of late death in lung recipients. BOS develops despite routine immunosuppression and its pathogenesis is poorly understood. The histological correlate of BOS is ...
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ConferenceThe Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · April 1, 2020
PURPOSE: The choice of single (SOLT) or bilateral orthotopic lung transplant (BOLT) for interstitial lung disease (ILD) remains controversial. Our center adopted a staged BOLT approach for higher surgical risk ILD patients, in which they undergo a single l ...
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ConferenceThe Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · April 1, 2020
PURPOSE: ECMO is increasingly used for bridging and salvage therapies in lung transplantation, with favorable short-term results. Mid- to long-term outcomes of ECMO use for bridging and salvage are incompletely understood, as is effect on PGD risk; therefo ...
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ConferenceThe Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · April 1, 2020
PURPOSE: The pulmonary microbiome modulates the immune milieu in the lung allograft and is in turn influenced by external factors such as microaspiration of oropharyngeal contents. A potential driver of microaspiration is gastroesophageal reflux disease (G ...
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ConferenceThe Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · April 1, 2020
PURPOSE: The occurrence of acute allograft injuries remains one of the most important factors responsible for the development of early chronic lung allograft dysfunction. We and others have previously demonstrated a consistent association between acute lun ...
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ConferenceThe Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · April 1, 2020
PURPOSE: Frailty is gaining increased recognition in the evaluation of lung transplant (LTx) candidates. The Fried Frailty Phenotype (FFP) index has been the most commonly used instrument and is associated with pre- and post-transplant morbidity and mortal ...
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ConferenceThe Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · April 1, 2020
PURPOSE: Diagnosis of CLAD after lung transplantation (LT) requires sustained decline in lung function and exclusion of other etiologies for the decline. The limitations of relying primarily on pulmonary function test (PFT) decline to define CLAD onset for ...
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ConferenceClin Transplant · July 2017
PURPOSE: Early research suggests prolonged ischemic time in older donor lungs is associated with decreased survival following lung transplantation. The purpose of this study was to determine whether this association holds in the post-lung allocation score ...
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ConferenceJ Heart Lung Transplant · January 2015
BACKGROUND: This study assessed treatment patterns and examined organ utilization in the setting of single-lung transplantation (SLT). METHODS: The United Network for Organ Sharing database was queried for all SLTs performed from 1987 to 2011. Trends in ut ...
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Purpose
Chronic lung allograft dysfunction (CLAD) is the leading cause of graft failure causing significant morbidity and mortality. Re-transplantation (L2Tx) after CLAD is historically associated with complicated peri-operative and post-operative courses ...
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