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Sarah Hollingsworth Lisanby

Professor Emeritus of Psychiatry and Behavioral Sciences
Psychiatry & Behavioral Sciences, Behavioral Medicine & Neurosciences
DUMC Box 3620, Durham, NC 27710
Room 5-4232. Red Zone, Box 3620 DUMC, Durham, NC 27710

Scholarly Works - Book sections


Next-generation seizure therapy

Book section · February 10, 2021 Electroconvulsive therapy (ECT) is highly effective in treating severe psychiatric conditions, but its cognitive side effects have been a limiting factor in its clinical use. Fortunately, decades of research have led to improvements in ECT technique that h ... Full text Cite

Magnetic Stimulation for Depression: Subconvulsive and Convulsive Approaches

Book section · March 5, 2016 Treatment-resistant depression remains an important clinical problem in need of novel treatment solutions. Electro-convulsive therapy and transcranial magnetic stimulation are two neuromodulation techniques with promise in the treatment of severe and chron ... Full text Cite

Magnetic Seizure Therapy for the Treatment of Depression

Book section · June 5, 2015 The magnetic approach to seizure therapy is based on the hypothesis that the electrical currents induced in deep brain structures by electroconvulsive therapy (ECT) may contribute to the adverse cognitive side effects. This chapter reviews the rationale fo ... Full text Cite

Brain Stimulation in Psychiatry

Book section · March 23, 2015 Full text Cite

TMS in the study and treatment of anxiety disorders

Book section · November 21, 2012 A few studies of transcranial magnetic stimulation (TMS) as an anxiety disorder treatment have been reported. In treatment studies, the focal application of TMS in the treatment of anxiety disorders has been guided by the present understanding of the neuro ... Full text Cite

Therapeutic potential of TMS-induced plasticity in the prefrontal cortex

Book section · November 21, 2012 This article discusses synaptic plasticity as a potential mechanism of enduring changes in function observed after relatively brief periods of repetitive (r)TMS. Plasticity is a use dependent enduring change in neural structure and function. The characteri ... Full text Cite

Methodological issues in clinical trial design for TMS

Book section · November 21, 2012 This article explores the emergence of transcranial magnetic stimulation (TMS) as a new therapeutic approach and the implications of this technology for the study and treatment of neuropsychiatric disorders, with a focus on major depression. Relapse, chron ... Full text Cite

Brain stimulation in the treatment of anxiety disorders

Book section · January 1, 2010 Introduction Brain stimulation represents a growing family of interventions that alter brain function using electrical fields that are either directly applied or indirectly induced using rapidly alternating magnetic fields. Brain stimulation techniques inc ... Full text Cite

Investigation of mood disorders by transcranial magnetic stimulation

Book section · January 1, 2002 TMS utilizes the principle of electromagnetic induction, which was first discovered by Michael Faraday in 1831. It involves the discharge of a large current (peak current: approximately 5000 amps) from a capacitor through a copper-wire coil. A rapid time-v ... Cite