Louis Frederic Diehl | Scholars@Duke

Louis Frederic Diehl
Professor of Medicine

Research interests include Hodgkin disease, non-Hodgkin lymphomas, Chronic Lymphocytic Leukemia, Acute Myeloid Leukemia, Acute Lymphocytic Leukemia, Myelodysplasia.

Current Appointments & Affiliations

Professor of Medicine, Medicine, Hematologic Malignancies and Cellular Therapy, Medicine 2017
Member of the Duke Cancer Institute, Duke Cancer Institute, Institutes and Centers 2013

Contact Information

2400 Pratt St Suite 5000, DUMC Box 3961, Durham, NC 27710
DUMC Box 3961, Durham, NC 27710
louis.diehl@duke.edu (919) 668-1000

Background
Education, Training, & Certifications
- Fellow in Hematology-Oncology, Medicine, Walter Reed Army Medical Center 1978 - 1981
- Medical Resident, Medicine, Walter Reed Army Medical Center 1975 - 1978
- M.D., Georgetown University 1975
Duke Appointment History
- Professor of Medicine, Medicine, Hematological Malignancies, Medicine 2012 - 2017
- Professor of Medicine, Medicine, Medical Oncology, Medicine 2006 - 2012
- Clinical Professor of Medicine, Medicine, Medical Oncology, Medicine 2005 - 2006
- Instructor, Temporary in the Department of Medicine, Medicine, Medical Oncology, Medicine 2004 - 2005
Recognition
In the News
- SEP 13, 2013 CBS News, AP
  
  FDA panel supports Perjeta for early-stage breast cancer
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Sung, Anthony D., Shekeab Jauhari, Sharareh Siamakpour-Reihani, Arati V. Rao, Janet Staats, Cliburn Chan, Everett Meyer, et al. “Microtransplantation in older patients with AML: A pilot study of safety, efficacy and immunologic effects.” Am J Hematol 95, no. 6 (June 2020): 662–71. https://doi.org/10.1002/ajh.25781.
    Full Text Link to Item
  - Diehl, Louis F. “The efficacy-toxicity conundrum: breaking the mold.” Blood 135, no. 10 (March 5, 2020): 704–6. https://doi.org/10.1182/blood.2019004464.
    Full Text Link to Item
  - Kelsey, Chris R., Gloria Broadwater, Olga James, Junzo Chino, Louis Diehl, Anne W. Beaven, Catherine Chang, Bridget F. Koontz, and Leonard R. Prosnitz. “Phase 2 Study of Dose-Reduced Consolidation Radiation Therapy in Diffuse Large B-Cell Lymphoma.” Int J Radiat Oncol Biol Phys 105, no. 1 (September 1, 2019): 96–101. https://doi.org/10.1016/j.ijrobp.2019.02.055.
    Full Text Link to Item
  - Chung, Shimin Jasmine, Rachel Ann Miller, Nitipong Permpalung, Arthur Wakefield Baker, Louis Frederic Diehl, David Alan Rizzieri, and Barbara Dudley Alexander. “Fluoroquinolone prophylaxis reduces febrile neutropenia, bloodstream infections from mucosal translocations, and intensive care admissions in high risk hematological patients, a single center experience.” Leuk Lymphoma 60, no. 2 (February 2019): 488–92. https://doi.org/10.1080/10428194.2018.1488252.
    Full Text Link to Item
  - Hudson, Kathryn E., David Rizzieri, Samantha M. Thomas, Thomas W. LeBlanc, Zachary Powell, Louis Diehl, Joseph O. Moore, Carlos DeCastro, and Anne W. Beaven. “Dose-intense chemoimmunotherapy plus radioimmunotherapy in high-risk diffuse large B-cell lymphoma and mantle cell lymphoma: a phase II study.” Br J Haematol 184, no. 4 (February 2019): 647–50. https://doi.org/10.1111/bjh.15138.
    Full Text Link to Item
  - Heyman, Benjamin, David Rizzieri, David J. Adams, Carlos De Castro, Louis Diehl, Zhiguo Li, Joseph Moore, and Anne Beaven. “Phase I Study of the Combination of Bendamustine, Rituximab, and Pixantrone in Patients With Relapsed/Refractory B-cell Non-Hodgkin Lymphoma.” Clin Lymphoma Myeloma Leuk 18, no. 10 (October 2018): 679–86. https://doi.org/10.1016/j.clml.2018.07.285.
    Full Text Link to Item
  - Mylam, Karen Juul, Lale Kostakoglu, Martin Hutchings, Morton Coleman, Dominick Lamonica, Myron S. Czuczman, Louis F. Diehl, et al. “(18)F-fluorodeoxyglucose-positron emission tomography/computed tomography after one cycle of chemotherapy in patients with diffuse large B-cell lymphoma: results of a Nordic/US intergroup study.” Leuk Lymphoma 56, no. 7 (July 2015): 2005–12. https://doi.org/10.3109/10428194.2014.975800.
    Full Text Link to Item
  - Torok, Jordan A., Yuan Wu, Leonard R. Prosnitz, Grace J. Kim, Anne W. Beaven, Louis F. Diehl, and Chris R. Kelsey. “Low-dose consolidation radiation therapy for early stage unfavorable Hodgkin lymphoma.” Int J Radiat Oncol Biol Phys 92, no. 1 (May 1, 2015): 54–59. https://doi.org/10.1016/j.ijrobp.2015.02.003.
    Full Text Link to Item
  - Beaven, Anne W., and Louis F. Diehl. “Peripheral T-cell lymphoma, NOS, and anaplastic large cell lymphoma.” Hematology Am Soc Hematol Educ Program 2015 (2015): 550–58. https://doi.org/10.1182/asheducation-2015.1.550.
    Full Text Link to Item
  - Boyle, John, Anne W. Beaven, Louis F. Diehl, Leonard R. Prosnitz, and Chris R. Kelsey. “Improving outcomes in advanced DLBCL: systemic approaches and radiotherapy.” Oncology (Williston Park) 28, no. 12 (December 2014): 1074–84.
    Link to Item
  - Hutchings, Martin, Lale Kostakoglu, Jan Maciej Zaucha, Bogdan Malkowski, Alberto Biggi, Iwona Danielewicz, Annika Loft, et al. “In vivo treatment sensitivity testing with positron emission tomography/computed tomography after one cycle of chemotherapy for Hodgkin lymphoma.” J Clin Oncol 32, no. 25 (September 1, 2014): 2705–11. https://doi.org/10.1200/JCO.2013.53.2838.
    Full Text Link to Item
  - Brander, Danielle, David Rizzieri, Jon Gockerman, Louis Diehl, Thomas Charles Shea, Carlos Decastro, Joseph O. Moore, and Anne Beaven. “Phase II open label study of the oral vascular endothelial growth factor-receptor inhibitor PTK787/ZK222584 (vatalanib) in adult patients with refractory or relapsed diffuse large B-cell lymphoma.” Leuk Lymphoma 54, no. 12 (December 2013): 2627–30. https://doi.org/10.3109/10428194.2013.784969.
    Full Text Link to Item
  - Held, Lauren A., David Rizzieri, Gwynn D. Long, Jon P. Gockerman, Louis F. Diehl, Carlos M. de Castro, Joseph O. Moore, Mitchell E. Horwitz, Nelson J. Chao, and Cristina Gasparetto. “A Phase I study of arsenic trioxide (Trisenox), ascorbic acid, and bortezomib (Velcade) combination therapy in patients with relapsed/refractory multiple myeloma.” Cancer Invest 31, no. 3 (March 2013): 172–76. https://doi.org/10.3109/07357907.2012.756109.
    Full Text Link to Item
  - DiLillo, D. J., J. B. Weinberg, A. Yoshizaki, M. Horikawa, J. M. Bryant, Y. Iwata, T. Matsushita, et al. “Chronic lymphocytic leukemia and regulatory B cells share IL-10 competence and immunosuppressive function.” Leukemia 27, no. 1 (January 2013): 170–82. https://doi.org/10.1038/leu.2012.165.
    Full Text Link to Item
  - Morris, Tod A., Carlos M. DeCastro, Louis F. Diehl, Jon P. Gockerman, Anand S. Lagoo, Zhiguo Li, Joseph O. Moore, David A. Rizzieri, and Arati V. Rao. “Re-induction therapy decisions based on day 14 bone marrow biopsy in acute myeloid leukemia.” Leuk Res 37, no. 1 (January 2013): 28–31. https://doi.org/10.1016/j.leukres.2012.09.016.
    Full Text Link to Item
  - Kelsey, Chris R., Anne W. Beaven, Louis F. Diehl, and Leonard R. Prosnitz. “Combined-modality therapy for early-stage Hodgkin lymphoma: maintaining high cure rates while minimizing risks.” Oncology (Williston Park) 26, no. 12 (December 2012): 1182–93.
    Link to Item
  - Dorth, Jennifer A., Leonard R. Prosnitz, Gloria Broadwater, Louis F. Diehl, Anne W. Beaven, R Edward Coleman, and Chris R. Kelsey. “Impact of consolidation radiation therapy in stage III-IV diffuse large B-cell lymphoma with negative post-chemotherapy radiologic imaging.” Int J Radiat Oncol Biol Phys 84, no. 3 (November 1, 2012): 762–67. https://doi.org/10.1016/j.ijrobp.2011.12.067.
    Full Text Link to Item
  - Rao, A. V., D. A. Rizzieri, C. M. DeCastro, L. F. Diehl, A. S. Lagoo, J. O. Moore, and J. P. Gockerman. “Phase I study of dose dense induction and consolidation with gemtuzumab ozogamicin and high dose cytarabine in older adults with AML.” Journal of Geriatric Oncology 3, no. 3 (July 1, 2012): 220–27. https://doi.org/10.1016/j.jgo.2012.02.002.
    Full Text
  - Lanasa, Mark C., Patricia H. Davis, Michael Datto, Zhiguo Li, Jon P. Gockerman, Joseph O. Moore, Carlos M. DeCastro, et al. “Phase II study of cenersen, an antisense inhibitor of p53, in combination with fludarabine, cyclophosphamide and rituximab for high-risk chronic lymphocytic leukemia.” Leuk Lymphoma 53, no. 2 (February 2012): 218–24. https://doi.org/10.3109/10428194.2011.610012.
    Full Text Link to Item
  - Kelsey, C. R., A. W. Beaven, L. F. Diehl, and L. R. Prosnitz. “Combined-modality therapy for early-stage Hodgkin lymphoma: Maintaining high cure rates while minimizing risks.” Oncology (United States) 26, no. 12 (January 1, 2012).
  - Christensen, Dale J., Youwei Chen, Jessica Oddo, Karen M. Matta, Jessica Neil, Evan D. Davis, Alicia D. Volkheimer, et al. “SET oncoprotein overexpression in B-cell chronic lymphocytic leukemia and non-Hodgkin lymphoma: a predictor of aggressive disease and a new treatment target.” Blood 118, no. 15 (October 13, 2011): 4150–58. https://doi.org/10.1182/blood-2011-04-351072.
    Full Text Link to Item
  - Dorth, J. A., J. P. Chino, L. R. Prosnitz, L. F. Diehl, A. W. Beaven, R. E. Coleman, and C. R. Kelsey. “The impact of radiation therapy in patients with diffuse large B-cell lymphoma with positive post-chemotherapy FDG-PET or gallium-67 scans.” Ann Oncol 22, no. 2 (February 2011): 405–10. https://doi.org/10.1093/annonc/mdq389.
    Full Text Link to Item
  - Advani, Anjali S., Mazyar Shadman, Francis Ali-Osman, Andrew Barker, Lisa Rybicki, Matt Kalaycio, Mikkael A. Sekeres, et al. “A Phase II trial of gemcitabine and mitoxantrone for patients with acute myeloid leukemia in first relapse.” Clin Lymphoma Myeloma Leuk 10, no. 6 (December 2010): 473–76. https://doi.org/10.3816/CLML.2010.n.082.
    Full Text Link to Item
  - Friedman, Daphne R., Lindsay A. Magura, Holly A. C. Warren, Jeremy D. Harrison, Louis F. Diehl, and J Brice Weinberg. “Statin use and need for therapy in chronic lymphocytic leukemia.” Leuk Lymphoma 51, no. 12 (December 2010): 2295–98. https://doi.org/10.3109/10428194.2010.520050.
    Full Text Link to Item
  - Kelsey, C. R., A. W. Beaven, L. F. Diehl, and L. R. Prosnitz. “Radiation therapy in the management of diffuse large B-cell lymphoma: still relevant?” Oncology (Williston Park, N.Y.) 24, no. 13 (November 30, 2010): 1204–12.
  - Kelsey, Chris R., Anne W. Beaven, Louis F. Diehl, and Leonard R. Prosnitz. “Radiation therapy in the management of diffuse large B-cell lymphoma: still relevant?” Oncology (Williston Park) 24, no. 13 (November 30, 2010): 1204–12.
    Link to Item
  - Mowery, Y. M., J. B. Weinberg, M. N. Kennedy, K. M. Bond, J. O. Moore, M. C. Lanasa, J. P. Gockerman, et al. “LMP-420: a novel purine nucleoside analog with potent cytotoxic effects for CLL cells and minimal toxicity for normal hematopoietic cells.” Leukemia 24, no. 9 (September 2010): 1580–87. https://doi.org/10.1038/leu.2010.150.
    Full Text Link to Item
  - Crout, Christopher A., Liang-Piu Koh, Jon P. Gockerman, Joseph O. Moore, Carlos Decastro, Gwynn D. Long, Louis Diehl, et al. “Overcoming drug resistance in mantle cell lymphoma using a combination of dose-dense and intense therapy.” Cancer Invest 28, no. 6 (July 2010): 654–60. https://doi.org/10.3109/07357901003631015.
    Full Text Link to Item
  - Gasparetto, Cristina, Jon P. Gockerman, Louis F. Diehl, Carlos M. de Castro, Joseph O. Moore, Gwynn D. Long, Mitchell E. Horwitz, et al. “"Short course" bortezomib plus melphalan and prednisone as induction prior to transplant or as frontline therapy for nontransplant candidates in patients with previously untreated multiple myeloma.” Biol Blood Marrow Transplant 16, no. 1 (January 2010): 70–77. https://doi.org/10.1016/j.bbmt.2009.08.017.
    Full Text Link to Item
  - Friedman, Daphne R., J Brice Weinberg, William T. Barry, Barbara K. Goodman, Alicia D. Volkheimer, Karen M. Bond, Youwei Chen, et al. “A genomic approach to improve prognosis and predict therapeutic response in chronic lymphocytic leukemia.” Clin Cancer Res 15, no. 22 (November 15, 2009): 6947–55. https://doi.org/10.1158/1078-0432.CCR-09-1132.
    Full Text Link to Item
  - Shah, Ankoor, Louis F. Diehl, and E William St Clair. “T cell large granular lymphocyte leukemia associated with rheumatoid arthritis and neutropenia.” Clin Immunol 132, no. 2 (August 2009): 145–52. https://doi.org/10.1016/j.clim.2009.03.515.
    Full Text Link to Item
  - Rizzieri, David A., Jenny A. O’Brien, Gloria Broadwater, Carlos M. Decastro, Prakash Dev, Louis Diehl, Anne Beaven, et al. “Outcomes of patients who undergo aggressive induction therapy for secondary acute myeloid leukemia.” Cancer 115, no. 13 (July 1, 2009): 2922–29. https://doi.org/10.1002/cncr.24379.
    Full Text Link to Item
  - Castro, C. de, D. Adams, D. Rizzieri, J. Moore, J. Gockerman, L. Diehl, M. Horwitz, E. Edmonds, and J. Warzecho. “P134 A phase II pilot study of sorafenib in patients with myelodysplastic syndromes.” Leukemia Research 33, no. SUPPL. 1 (May 1, 2009). https://doi.org/10.1016/S0145-2126(09)70215-2.
    Full Text
  - Castro, C. de, D. Adams, D. Rizzieri, J. Moore, J. Gockerman, L. Diehl, M. Horwitz, E. Edmonds, and J. Warzecho. “P129 A pilot study of decitabine in combination with arsenic trioxide for patients with myelodysplastic syndromes.” Leukemia Research 33, no. SUPPL. 1 (May 1, 2009). https://doi.org/10.1016/S0145-2126(09)70210-3.
    Full Text
  - Weinberg, J. B., A. D. Volkheimer, M. Mihovilovic, N. Jiang, Y. Chen, K. Bond, J. O. Moore, et al. “Apolipoprotein E genotype as a determinant of survival in chronic lymphocytic leukemia.” Leukemia 22, no. 12 (December 2008): 2184–92. https://doi.org/10.1038/leu.2008.241.
    Full Text Link to Item
  - Christensen, Dale J., Karen M. Bond, Alicia D. Volkheimer, Jessica Oddo, Youwei Chen, Jon P. Gockerrnan, Joseph O. Moore, et al. “Apolipoprotein E-Mimetic Therapeutic Peptides Mediate CLL Cell Cytotoxicity.” Blood 112, no. 11 (November 16, 2008): 140–140.
    Link to Item
  - Gasparet, Cristina, Jon P. Gockerman, Louis F. Diehl, Carlos De Castro, Joseph Moore, Gwynn D. Long, Mitchell Horwitz, et al. “Bortezomib Plus Melphalan and Prednisone as Induction Prior to Transplant or as Frontline Therapy for Non-Transplant Candidates in Patients with Previously Untreated Multiple Myeloma.” Blood 112, no. 11 (November 16, 2008): 1142–1142.
    Link to Item
  - Weinberg, J Brice, Alicia D. Volkheimer, Youwei Chen, Bethany E. Beasley, Ning Jiang, Mark C. Lanasa, Daphne Friedman, et al. “Clinical and molecular predictors of disease severity and survival in chronic lymphocytic leukemia.” Am J Hematol 82, no. 12 (December 2007): 1063–70. https://doi.org/10.1002/ajh.20987.
    Full Text Link to Item
  - Berdeja, Jesús G., Allan Hess, David M. Lucas, Paul O’Donnell, Richard F. Ambinder, Louis F. Diehl, Denise Carter-Brookins, Susan Newton, and Ian W. Flinn. “Systemic interleukin-2 and adoptive transfer of lymphokine-activated killer cells improves antibody-dependent cellular cytotoxicity in patients with relapsed B-cell lymphoma treated with rituximab.” Clin Cancer Res 13, no. 8 (April 15, 2007): 2392–99. https://doi.org/10.1158/1078-0432.CCR-06-1860.
    Full Text Link to Item
  - Willis, Carl R., Amy Goodrich, Kathy Park, Jamie K. Waselenko, Margaret Lucas, Amy Reese, Louis F. Diehl, Michael R. Grever, John C. Byrd, and Ian W. Flinn. “A phase I/II study examining pentostatin, chlorambucil, and theophylline in patients with relapsed chronic lymphocytic leukemia and non-Hodgkin's lymphoma.” Ann Hematol 85, no. 5 (May 2006): 301–7. https://doi.org/10.1007/s00277-005-0025-9.
    Full Text Link to Item
  - Kasamon, Yvette L., Ian W. Flinn, Michael R. Grever, Louis F. Diehl, Elizabeth Garrett-Mayer, Steven N. Goodman, Margaret S. Lucas, and John C. Byrd. “Phase I study of low-dose interleukin-2, fludarabine, and cyclophosphamide for previously untreated indolent lymphoma and chronic lymphocytic leukemia.” Clin Cancer Res 11, no. 23 (December 1, 2005): 8413–17. https://doi.org/10.1158/1078-0432.CCR-05-1612.
    Full Text Link to Item
  - Matsui, William, B Douglas Smith, Milada Vala, Nikeshia Beal, Carol Ann Huff, Louis F. Diehl, and Richard J. Jones. “Requirement for myeloid growth factors in the differentiation of acute promyelocytic leukaemia.” Br J Haematol 128, no. 6 (March 2005): 853–62. https://doi.org/10.1111/j.1365-2141.2005.05395.x.
    Full Text Link to Item
  - Kasamon, Yvette L., Richard J. Jones, Louis F. Diehl, Hassan Nayer, Michael J. Borowitz, Elizabeth Garrett-Mayer, Richard F. Ambinder, Ross A. Abrams, Zhe Zhang, and Ian W. Flinn. “Outcomes of autologous and allogeneic blood or marrow transplantation for mantle cell lymphoma.” Biol Blood Marrow Transplant 11, no. 1 (January 2005): 39–46. https://doi.org/10.1016/j.bbmt.2004.09.007.
    Full Text Link to Item
  - Huff, Carol Ann, Ephraim J. Fuchs, Stephen J. Noga, Paul V. O’Donnell, Richard F. Ambinder, Louis Diehl, Ivan Borrello, et al. “Long-term follow-up of T cell-depleted allogeneic bone marrow transplantation in refractory multiple myeloma: importance of allogeneic T cells.” Biol Blood Marrow Transplant 9, no. 5 (May 2003): 312–19. https://doi.org/10.1016/s1083-8791(03)00075-2.
    Full Text Link to Item
  - Willard, R. J., G. W. Turiansky, G. P. Genest, B. J. Davis, and L. F. Diehl. “Leukemia cutis in a patient with chronic neutrophilic leukemia.” J Am Acad Dermatol 44, no. 2 Suppl (February 2001): 365–69. https://doi.org/10.1067/mjd.2001.103996.
    Full Text Link to Item
  - Flinn, I. W., J. C. Byrd, C. Morrison, J. Jamison, L. F. Diehl, T. Murphy, S. Piantadosi, et al. “Fludarabine and cyclophosphamide with filgrastim support in patients with previously untreated indolent lymphoid malignancies.” Blood 96, no. 1 (July 1, 2000): 71–75.
    Link to Item
  - Flinn, I. W., S. N. Goodman, L. Post, J. Jamison, C. B. Miller, S. Gore, L. Diehl, C. Willis, R. F. Ambinder, and J. C. Byr. “A dose-finding study of liposomal daunorubicin with CVP (COP-X) in advanced NHL.” Ann Oncol 11, no. 6 (June 2000): 691–95. https://doi.org/10.1023/a:1008361914894.
    Full Text Link to Item
  - LeBrun, C. J., L. F. Diehl, K. C. Abbott, P. G. Welch, and C. M. Yuan. “Life expectancy benefits of cancer screening in the end-stage renal disease population.” Am J Kidney Dis 35, no. 2 (February 2000): 237–43. https://doi.org/10.1016/s0272-6386(00)70332-5.
    Full Text Link to Item
  - Diehl, L. F., L. H. Karnell, and H. R. Menck. “The American College of Surgeons Commission on Cancer and the American Cancer Society. The National Cancer Data Base report on age, gender, treatment, and outcomes of patients with chronic lymphocytic leukemia.” Cancer 86, no. 12 (December 15, 1999): 2684–92.
    Link to Item
  - Byrd, J. C., L. H. McGrail, D. R. Hospenthal, R. S. Howard, N. A. Dow, and L. F. Diehl. “Herpes virus infections occur frequently following treatment with fludarabine: results of a prospective natural history study.” Br J Haematol 105, no. 2 (May 1999): 445–47.
    Link to Item
  - Shorr, A. F., R. F. Trotta, S. A. Alkins, G. S. Hanzel, and L. F. Diehl. “D-dimer assay predicts mortality in critically ill patients without disseminated intravascular coagulation or venous thromboembolic disease.” Intensive Care Med 25, no. 2 (February 1999): 207–10. https://doi.org/10.1007/s001340050817.
    Full Text Link to Item
  - Byrd, J. C., C. Shinn, J. K. Waselenko, E. J. Fuchs, T. A. Lehman, P. L. Nguyen, I. W. Flinn, L. F. Diehl, E. Sausville, and M. R. Grever. “Flavopiridol induces apoptosis in chronic lymphocytic leukemia cells via activation of caspase-3 without evidence of bcl-2 modulation or dependence on functional p53.” Blood 92, no. 10 (November 15, 1998): 3804–16.
    Link to Item
  - Weiss, R. B., J. Freiman, S. L. Kweder, L. F. Diehl, and J. C. Byrd. “Hemolytic anemia after fludarabine therapy for chronic lymphocytic leukemia.” J Clin Oncol 16, no. 5 (May 1998): 1885–89. https://doi.org/10.1200/JCO.1998.16.5.1885.
    Full Text Link to Item
  - Kornblith, A. B., J. E. Herndon, E. Zuckerman, D. F. Cella, E. Cherin, S. Wolchok, R. B. Weiss, et al. “Comparison of psychosocial adaptation of advanced stage Hodgkin's disease and acute leukemia survivors. Cancer and Leukemia Group B.” Ann Oncol 9, no. 3 (March 1998): 297–306. https://doi.org/10.1023/a:1008297130258.
    Full Text Link to Item
  - Diehl, L. F., and L. H. Ketchum. “Autoimmune disease and chronic lymphocytic leukemia: autoimmune hemolytic anemia, pure red cell aplasia, and autoimmune thrombocytopenia.” Semin Oncol 25, no. 1 (February 1998): 80–97.
    Link to Item
  - Wiesen, A. R., J. C. Byrd, D. R. Hospenthal, R. S. Howard, A. R. Shorr, K. L. Glass, and L. F. Diehl. “Transient abnormalities in serum bilirubin and lactate dehydrogenase levels following red blood cell transfusions in adults.” Am J Med 104, no. 2 (February 1998): 144–47. https://doi.org/10.1016/s0002-9343(97)00398-7.
    Full Text Link to Item
  - Shields, D. J., J. C. Byrd, S. L. Abbondanzo, J. H. Lichy, L. F. Diehl, and N. I. Aguilera. “Detection of Epstein-Barr virus in transformations of low-grade B-cell lymphomas after fludarabine treatment.” Mod Pathol 10, no. 11 (November 1997): 1151–59.
    Link to Item
  - Ringel, M. D., T. Taylor, A. Barsouk, J. R. Wall, C. E. Freter, R. S. Howard, L. Diehl, and K. D. Burman. “Hodgkin's disease treated with neck radiation is associated with increased antibody-dependent cellular cytotoxicity against human extraocular muscle cells.” Thyroid 7, no. 3 (June 1997): 425–32. https://doi.org/10.1089/thy.1997.7.425.
    Full Text Link to Item
  - Diehl, L. F., C. D. Bolan, and R. B. Weiss. “Hemolytic anemia and cancer.” Cancer Treat Rev 22, no. 1 (January 1996): 33–73. https://doi.org/10.1016/s0305-7372(96)90015-8.
    Full Text Link to Item
  - Solimando, D. A., E. T. Phillips, R. B. Weiss, N. A. Dawson, L. F. Diehl, and N. M. Rickles. “Hypertensive reactions associated with paclitaxel.” Cancer Invest 14, no. 4 (1996): 340–42. https://doi.org/10.3109/07357909609012161.
    Full Text Link to Item
  - Byrd, J. C., J. B. Hargis, K. E. Kester, D. R. Hospenthal, S. W. Knutson, and L. F. Diehl. “Opportunistic pulmonary infections with fludarabine in previously treated patients with low-grade lymphoid malignancies: a role for Pneumocystis carinii pneumonia prophylaxis.” Am J Hematol 49, no. 2 (June 1995): 135–42. https://doi.org/10.1002/ajh.2830490207.
    Full Text Link to Item
  - Byrd, J. C., A. A. Hertler, R. B. Weiss, J. Freiman, S. L. Kweder, and L. F. Diehl. “Fatal recurrence of autoimmune hemolytic anemia following pentostatin therapy in a patient with a history of fludarabine-associated hemolytic anemia.” Ann Oncol 6, no. 3 (March 1995): 300–301. https://doi.org/10.1093/oxfordjournals.annonc.a059162.
    Full Text Link to Item
  - Wiesen, A. R., D. R. Hospenthal, J. C. Byrd, K. L. Glass, R. S. Howard, and L. F. Diehl. “Equilibration of hemoglobin concentration after transfusion in medical inpatients not actively bleeding.” Ann Intern Med 121, no. 4 (August 15, 1994): 278–230. https://doi.org/10.7326/0003-4819-121-4-199408150-00009.
    Full Text Link to Item
  - Vukelja, S. J., J. Krishnan, and L. F. Diehl. “Mean platelet volume improves upon the megathrombocyte index but cannot replace the blood film examination in the evaluation of thrombocytopenia.” Am J Hematol 44, no. 2 (October 1993): 89–94. https://doi.org/10.1002/ajh.2830440204.
    Full Text Link to Item
  - Reed, W. W., and L. F. Diehl. “In Reply.” Archives of Internal Medicine 152, no. 6 (January 1, 1992): 1329. https://doi.org/10.1001/archinte.1992.00400180165030.
    Full Text
  - Tomases, A., W. W. Reed, L. F. Diehl, and D. Bessman. “Congenital neutropenia: How low? [1].” Archives of Internal Medicine 152, no. 6 (1992).
  - Diehl, L. F. “Radiation and chemotherapy in the treatment of esophageal cancer.” Gastroenterol Clin North Am 20, no. 4 (December 1991): 765–74.
    Link to Item
  - Hopper, K. D., L. F. Diehl, J. C. Lynch, and M. A. McCauslin. “Mediastinal bulk in Hodgkin disease. Method of measurement versus prognosis.” Invest Radiol 26, no. 12 (December 1991): 1101–10. https://doi.org/10.1097/00004424-199112000-00015.
    Full Text Link to Item
  - Diehl, L. F., K. D. Hopper, J. Giguere, E. Granger, and M. Lesar. “The pattern of intrathoracic Hodgkin's disease assessed by computed tomography.” J Clin Oncol 9, no. 3 (March 1991): 438–43. https://doi.org/10.1200/JCO.1991.9.3.438.
    Full Text Link to Item
  - Reed, W. W., and L. F. Diehl. “Leukopenia, neutropenia, and reduced hemoglobin levels in healthy American blacks.” Arch Intern Med 151, no. 3 (March 1991): 501–5.
    Link to Item
  - Hargis, J. B., D. J. Waddell, L. Diehl, and J. Redmond. “Induction chemotherapy in Jehovah's Witnesses with leukaemia.” Lancet 336, no. 8714 (September 1, 1990): 563–64. https://doi.org/10.1016/0140-6736(90)92117-z.
    Full Text Link to Item
  - Hopper, K. D., L. F. Diehl, B. A. Cole, J. C. Lynch, J. W. Meilstrup, and M. A. McCauslin. “The significance of necrotic mediastinal lymph nodes on CT in patients with newly diagnosed Hodgkin disease.” Ajr Am J Roentgenol 155, no. 2 (August 1990): 267–70. https://doi.org/10.2214/ajr.155.2.2115249.
    Full Text Link to Item
  - Vukelja, S. J., Y. Andejeski, J. K. Giguere, A. Yuen, and L. F. Diehl. “Enlargement of mediastinal masses on simulation films: a radiotherapeutic problem in the management of patients with Hodgkin's disease.” Med Pediatr Oncol 18, no. 1 (1990): 44–48. https://doi.org/10.1002/mpo.2950180109.
    Full Text Link to Item
  - Simmons, J. O., G. L. Noel, and L. F. Diehl. “Does review of peripheral blood smears help in the initial workup of common anemias?” J Gen Intern Med 4, no. 6 (November 1989): 473–81. https://doi.org/10.1007/BF02599543.
    Full Text Link to Item
  - Ellis, M. E., L. F. Diehl, E. Granger, and E. Elson. “Trephine needle bone marrow biopsy in the initial staging of Hodgkin disease: sensitivity and specificity of the Ann Arbor staging procedure criteria.” Am J Hematol 30, no. 3 (March 1989): 115–20. https://doi.org/10.1002/ajh.2830300302.
    Full Text Link to Item
  - Hopper, K. D., and L. F. Diehl. “RE: Hodgkin disease Clinical utility of CT in initial staging and treatment.” Investigative Radiology 24, no. 10 (January 1, 1989).
  - Hopper, K. D., L. F. Diehl, M. Lesar, M. Barnes, E. Granger, and J. Baumann. “Hodgkin disease: clinical utility of CT in initial staging and treatment.” Radiology 169, no. 1 (October 1988): 17–22. https://doi.org/10.1148/radiology.169.1.3420256.
    Full Text Link to Item
  - Diehl, L. F., A. Banks, W. Carter, M. A. Klein, H. B. Muss, and R. B. Weiss. “Fatal esorubicin-induced cardiomyopathy: report of a case and review of the literature.” Cancer Chemother Pharmacol 21, no. 4 (1988): 347–50. https://doi.org/10.1007/BF00264203.
    Full Text Link to Item
  - Glass, A. R., W. Reed, and L. Diehl. “Hematologic indexes in men attending an infertility clinic.” Arch Androl 20, no. 2 (1988): 177–80. https://doi.org/10.3109/01485018808987071.
    Full Text Link to Item
  - Diehl, L. F., and D. J. Perry. “A comparison of randomized concurrent control groups with matched historical control groups: are historical controls valid?” J Clin Oncol 4, no. 7 (July 1986): 1114–20. https://doi.org/10.1200/JCO.1986.4.7.1114.
    Full Text Link to Item
  - Perry, D. J., and L. F. Diehl. “Changes in criteria for tumor response.” J Clin Oncol 3, no. 2 (February 1985): 287. https://doi.org/10.1200/JCO.1985.3.2.287.
    Full Text Link to Item
  - Diehl, L. F., M. A. Hurwitz, S. A. Johnson, W. M. Butler, and H. G. Taylor. “Skin metastases confined to a field of previous irradiation. Report of two cases and review of the literature.” Cancer 53, no. 9 (May 1, 1984): 1864–68. https://doi.org/10.1002/1097-0142(19840501)53:9<1864::aid-cncr2820530912>3.0.co;2-2.
    Full Text Link to Item
  - Adams, J. D., L. F. Diehl, and J. P. Wilson. “Ambulatory use of high-dose intravenous morphine for severe pain.” Drug Intell Clin Pharm 18, no. 2 (February 1984): 138–40. https://doi.org/10.1177/106002808401800208.
    Full Text Link to Item
  - Diehl, L. F., D. J. Perry, and D. B. Tang. “Study on the comparability of 6 versus 12 cycles of adjuvant cyclophosphamide, methotrexate, and fluorouracil.” J Clin Oncol 1, no. 10 (October 1983): 663–64. https://doi.org/10.1200/JCO.1983.1.10.663.
    Full Text Link to Item
  - Diehl, L. F., D. J. Perry, H. Terebelo, P. E. Baldwin, M. Hurwitz, D. B. Kimball, and R. V. Dorn. “Radiation as salvage therapy for patients with Hodgkin's disease relapsing after MOPP (mechlorethamine, vincristine, prednisone, and procarbazine) chemotherapy.” Cancer Treat Rep 67, no. 9 (September 1983): 827–29.
    Link to Item
  - Butler, W. M., L. F. Diehl, H. G. Taylor, and M. D. Weltz. “Metastatic thymoma with myasthenia gravis: complete remission with combination chemotherapy.” Cancer 50, no. 3 (August 1, 1982): 419–22. https://doi.org/10.1002/1097-0142(19820801)50:3<419::aid-cncr2820500306>3.0.co;2-a.
    Full Text Link to Item
  - Schoomaker, E. B., W. M. Butler, and L. F. Diehl. “Increased heat sensitivity of red blood cells in hereditary elliptocytosis with acquired cobalamin (vitamin B12) deficiency.” Blood 59, no. 6 (June 1982): 1213–19.
    Link to Item
  - Diehl, L., D. Perry, and H. Terebelo. “Radiation as salvage therapy for patients with Hodgkin's disease (HD) relapsing after MOPP chemotherapy.” Proceedings of the American Society of Clinical Oncology Vol. 1 (January 1, 1982).
  - Hooks, J. J., B. F. Haynes, B. Detrick-Hooks, L. F. Diehl, T. L. Gerrard, and A. S. Fauci. “Gamma (immune) interferon production by leukocytes from a patient with a TG cell proliferative disease.” Blood 59, no. 1 (January 1982): 198–201.
    Link to Item
  - Butler, W. M., H. G. Taylor, and L. F. Diehl. “Lhermitte's sign in cobalamin (vitamin B12) deficiency.” Jama 245, no. 10 (March 13, 1981): 1059.
    Link to Item
  - Hooks, J. J., B. F. Haynes, B. Detrick-Hooks, L. F. Diehl, T. L. Gerrard, and A. S. Fauci. “Gamma (immune) interferon produced by leukocytes from a patients with a T cell proliferation disease.” Trans Assoc Am Physicians 94 (1981): 198–203.
    Link to Item
- Conference Papers
  - Sung, Anthony D., Carlos M. de Castro, Thomas W. LeBlanc, Gwynn D. Long, Donna B. Adams, Danielle M. Brander, Sandeep Dave, et al. “Clinical Outcomes of Microtransplantation for Older Adults with Acute Myeloid Leukemia.” In Blood, Vol. 130. AMER SOC HEMATOLOGY, 2017.
    Link to Item
  - Sivaraj, Dharshan, Michael M. Green, Yubin Kang, David Rizzieri, Louis F. Diehl, Anne W. Beaven, Zhiguo Li, et al. “Phase I/II dose expansion of a trial investigating bendamustine and pomalidomide with dexamethasone (BPd) in patients with relapsed/refractory multiple myeloma.” In Journal of Clinical Oncology, 35:8008–8008. American Society of Clinical Oncology (ASCO), 2017. https://doi.org/10.1200/jco.2017.35.15_suppl.8008.
    Full Text
  - Gasparetto, Cristina, Michael Green, Anandgopal Srinivasan, Yubin Kang, David A. Rizzieri, Carlos Decastro, Louis F. Diehl, et al. “A Phase I-II Study of the Combination of Bendamustine and Pomalidomide with Dexamethasone in Patients with Relapsed or Refractory Multiple Myeloma.” In Blood, 126:1857–1857. American Society of Hematology, 2015. https://doi.org/10.1182/blood.v126.23.1857.1857.
    Full Text
  - Ali, H. A., L. D. Snyder, L. F. Diehl, J. L. Todd, and S. Aryal. “Atypical Primary Effusion Lymphoma In A Lung Transplant Recipient.” In American Journal of Respiratory and Critical Care Medicine, Vol. 191. AMER THORACIC SOC, 2015.
    Link to Item
  - Brander, Danielle M., Anne W. Beaven, Jon P. Gockerman, Louis F. Diehl, Cristina Gasparetto, Thomas C. Shea, Carlos deCastro, Joseph O. Moore, and David A. Rizzieri. “Phase II Study of VEGF Inhibitor, PTK787/ZK222584, in Patients with Refractory or Relapsed Diffuse Large B-Cell Lymphoma.” In Blood, 120:1626–1626. American Society of Hematology, 2012. https://doi.org/10.1182/blood.v120.21.1626.1626.
    Full Text
  - Rao, Arati, David A. Rizzieri, Eduardo Vanegas, Joseph O. Moore, Jon P. Gockerman, Louis F. Diehl, Donna Adams, Julie Warzecho, and Carlos Decastro. “Pilot Study of Sorafenib for Myelodysplastic Syndrome.” In Blood, 120:4948–4948. American Society of Hematology, 2012. https://doi.org/10.1182/blood.v120.21.4948.4948.
    Full Text
  - Rao, Arati, Ghazi Khan, David A. Rizzieri, Joseph O. Moore, Jon P. Gockerman, Louis F. Diehl, Anne W. Beaven, Donna Adams, Julie Warzecho, and Carlos Decastro. “Phase 1 Study of Lenalidomide and Decitabine for High and Intermediate 2 Risk MDS.” In Blood, 120:4935–4935. American Society of Hematology, 2012. https://doi.org/10.1182/blood.v120.21.4935.4935.
    Full Text
  - Beaven, Anne W., David A. Rizzieri, Zachary Powell, Zhiguo Li, Peggy Alton, Julie Warzecho, Louis F. Diehl, Joseph O. Moore, Carlos Manuel de Castro, and Jon P. Gockerman. “High Complete Response Rates with Dose Dense/Dose Intense Chemotherapy Plus Radioimmunotherapy in High Risk Diffuse Large B Cell and Mantle Cell Lymphoma.” In Blood, 118:1152–1152. AMER SOC HEMATOLOGY, 2011.
    Link to Item
  - Morris, Tod A., David A. Rizzieri, Carlos M. de Castro, Louis F. Diehl, Jon P. Gockerman, Anand S. Lagoo, Joseph O. Moore, and Arati V. Rao. “Re-Induction Therapy Decisions Based on Day 14 Bone Marrow Biopsy in Acute Myeloid Leukemia.” In Blood, 118:1532–33. AMER SOC HEMATOLOGY, 2011.
    Link to Item
  - Weinberg, J Brice, David J. DiLillo, Yohei Iwata, Takashi Matushita, Karen M. Matta, Guglielmo M. Venturi, Giandomenico Russo, et al. “Chronic Lymphocytic Leukemia Shares a Common Cellular Origin with Regulatory B10 Cells.” In Blood, 118:132–33. AMER SOC HEMATOLOGY, 2011.
    Link to Item

Some information on this profile has been compiled automatically from Duke databases and external sources. (Our About page explains how this works.) If you see a problem with the information, please write to Scholars@Duke and let us know. We will reply promptly.

Education, Training, & Certifications

Duke Appointment History

In the News

Selected Publications

Academic Articles

Conference Papers