Scholarly Works - Preprints
Preprint
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July 23, 2026
Naturally occurring isoforms of the proto-oncogene Erb-B2 Receptor Tyrosine Kinase 2 (ERBB2, HER2) incite unique pathways of tumor progression in mouse models of breast cancer. Although each isoform has been shown to progress to metastasis, the N-terminall ...
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Preprint
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May 14, 2025
Fluorescent proteins (FPs) have revolutionized spatiotemporal observations in biology. Yet, the design of multiplexed assays remains constrained by limited spectral characterization and palette validation. Although over 1,000 FPs have been catalogued, syst ...
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Preprint
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2025
Cancer immunotherapy offers a promising long-term treatment for solid tumors by activating the immune system, but side effects and systemic toxicity limit its broad clinical translation. While intratumoral delivery addresses these limitations, elevated sti ...
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Preprint
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August 12, 2024
Cancer screening is based upon a linear model of neoplastic growth and malignant progression. Yet, historical observations suggest that malignant progression is uncoupled from growth which may explain the paradoxical increase in early-stage breast cancer d ...
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