Mai ElMallah

Journal article Proc Natl Acad Sci U S A · March 13, 2018 Featured Publication Chronic obstructive pulmonary disease affects 10% of the worldwide population, and the leading genetic cause is α-1 antitrypsin (AAT) deficiency. Due to the complexity of the murine locus, which includes up to six Serpina1 paralogs, no genetic animal model ... Full text Link to item Cite

Gene Therapy 2017: Progress and Future Directions.

Journal article Clin Transl Sci · July 2017 Featured Publication Full text Link to item Cite

Airway smooth muscle dysfunction in Pompe (Gaa-/- ) mice.

Journal article Am J Physiol Lung Cell Mol Physiol · June 1, 2017 Featured Publication Pompe disease is an autosomal recessive disorder caused by a deficiency of acid α-glucosidase (GAA), an enzyme responsible for hydrolyzing lysosomal glycogen. Deficiency of GAA leads to systemic glycogen accumulation in the lysosomes of skeletal muscle, mo ... Full text Link to item Cite

Restrictive Lung Disease in the Cu/Zn Superoxide-Dismutase 1 G93A Amyotrophic Lateral Sclerosis Mouse Model.

Journal article Am J Respir Cell Mol Biol · March 2017 Featured Publication Full text Link to item Cite

Ampakine CX717 potentiates intermittent hypoxia-induced hypoglossal long-term facilitation.

Journal article J Neurophysiol · September 1, 2016 Featured Publication Glutamatergic currents play a fundamental role in regulating respiratory motor output and are partially mediated by α-amino-3-hydroxy-5-methyl-isoxazole-propionic acid (AMPA) receptors throughout the premotor and motor respiratory circuitry. Ampakines are ... Full text Link to item Cite