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Manesh Raman Patel

Richard Sean Stack, M.D. Distinguished Professor
Medicine, Cardiology
DUMC 3330, Durham, NC 27710
2301 Erwin Road, Hafs Building, Room 8695, Durham, NC 27710

Selected Grants


1/2 IMPRoving Outcomes in Vascular DisEase - Aortic Dissection (IMPROVE-AD)

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2024 - 2030

Splanchnic Nerve Modulation In Heart Failure (Splanchnic X)

ResearchCollaborator · Awarded by National Institutes of Health · 2024 - 2029

SPYRAL AFFIRM

Clinical TrialPrincipal Investigator · Awarded by Medtronic Vascular, Inc. · 2024 - 2029

Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure

Clinical TrialCo-Principal Investigator · Awarded by Procyrion, Inc. · 2023 - 2026

1/2 IMPRoving Outcomes in Vascular DisEase - Aortic Dissection (IMPROVE-AD)

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2024 - 2030

Splanchnic Nerve Modulation In Heart Failure (Splanchnic X)

ResearchCollaborator · Awarded by National Institutes of Health · 2024 - 2029

SPYRAL AFFIRM

Clinical TrialPrincipal Investigator · Awarded by Medtronic Vascular, Inc. · 2024 - 2029

Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure

Clinical TrialCo-Principal Investigator · Awarded by Procyrion, Inc. · 2023 - 2026

THE MARIO FAMILY FOUNDATION SCHOLARS PROGRAM

Inst. Training Prgm or CMEPrincipal Investigator · Awarded by Mario Family Foundation · 2021 - 2026

Health AI Partnership Phase II

Institutional SupportPrincipal Investigator · Awarded by Gordon & Betty Moore Foundation · 2021 - 2025

1/2 Low dose colchicine in pAtients with peripheral artery DiseasE to assess residual vascular risk (LEADER-PAD)

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2024 - 2025

Role of the Splanchnic Vascular Compartment in Heart Failure with Preserved Ejection Fraction

ResearchMentor · Awarded by Doris Duke Charitable Foundation, Inc. · 2022 - 2025

BEST-VIVA Registry (vCLI)

ResearchPrincipal Investigator · Awarded by VIVA Physicians Inc. · 2019 - 2025

Postdoctoral Training in Cardiovascular Clinical Research

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2003 - 2025

BEST-VIVA Registry (vCLI)

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2019 - 2025

Early Detection of Sepsis using Artificial Intelligence

ResearchPrincipal Investigator · Awarded by Cohere Med Inc. · 2022 - 2024

OCEANIC

ResearchPrincipal Investigator · Awarded by Bayer AG · 2022 - 2024

Changing the Trajectory of Sudden Death Among Athletes

ResearchPrincipal Investigator · Awarded by American Heart Association · 2022 - 2024

AEGIS II

Clinical TrialPrincipal Investigator · Awarded by CSL Behring LLC · 2018 - 2024

1/2 IMPRoving Outcomes in Vascular DisEase - Aortic Dissection (IMPROVE-AD)

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2023 - 2024

Inflammatory and Metabolic Biomarkers in Cardiovascular Complications with SARS-CoV-2

ResearchCo Investigator · Awarded by National Institutes of Health · 2021 - 2024

OCEANIC-AF

ResearchPrincipal Investigator · Awarded by Bayer Healthcare Pharmaceuticals Inc · 2022 - 2024

Analytical tools and documentation frameworks for health AI software audits, evaluations, and monitoring

ResearchPrincipal Investigator · Awarded by Patrick J McGovern Foundation · 2021 - 2023

SPYRAL-HTN-ON MED

Clinical TrialPrincipal Investigator · Awarded by Medtronic, Inc. · 2015 - 2023

SPYRAL OFF MEDS

Clinical TrialPrincipal Investigator · Awarded by Medtronic, Inc. · 2015 - 2023

Identifying Cardiac Decompensation/Shock: Early Diagnosis and Improving In-Hospital Outcomes

ResearchPrincipal Investigator · Awarded by Gordon & Betty Moore Foundation · 2021 - 2023

Is Heart Failure with Preserved Edection Fraction the Symptomatic Manifestation of Liver Disease

ResearchCollaborator · Awarded by American Heart Association · 2021 - 2022

Radiographic imaging Validation and EvALuation for Angio iFR (ReVEAL iFR)

Clinical TrialPrincipal Investigator · Awarded by Volcano Corporation · 2020 - 2022

Protocol #s 19765, 19766, and 20603: ACS and Afib Trials

Clinical TrialPrincipal Investigator · Awarded by Bayer Pharmaceuticals · 2020 - 2022

Congestion Phenotypes and Splanchnic Nerve Modulation in Chronic Heart Failure

Clinical TrialCo-Mentor · Awarded by National Institutes of Health · 2020 - 2022

Enhanced X-ray Angiography Analysis and Interpretation Using Deep Learning

ResearchCo-Principal Investigator · Awarded by Vigilant Medical · 2019 - 2022

Shield II

Clinical TrialPrincipal Investigator · Awarded by Thoratec Corporation · 2016 - 2022

Vascular Protection Initiative

ResearchPrincipal Investigator · Awarded by Bayer Pharmaceuticals · 2018 - 2021

"Heart Failure & Comorbidities Analysis from the American Heart Association Scientific Sessions 2020: Integrating Data into Clinical Practice in the Era of COVID-19."

Inst. Training Prgm or CMEPrincipal Investigator · Awarded by Boehringer Ingelheim Corporation · 2020 - 2021

DEFINE-PCI

Clinical TrialPrincipal Investigator · Awarded by Volcano Corporation · 2017 - 2021

ADAPTABLE

Clinical TrialCo Investigator · Awarded by Vanderbilt University Medical Center · 2016 - 2021

ASCVD LEARNING LAB

Inst. Training Prgm or CMEPrincipal Investigator · Awarded by Novartis Consumer Health, Inc. · 2020 - 2020

ROX HTN

Clinical TrialPrincipal Investigator · Awarded by ROX Medical · 2017 - 2020

Patient Reported Preferences Affecting Revascularization Decisions

ResearchPrincipal Investigator · Awarded by Gilead Sciences, Inc. · 2015 - 2020

AHA project

ResearchInvestigator · Awarded by American Heart Association · 2018 - 2019

Splanchnic Nerve Block for Therapy of Acute Heart Failure (Splanchnic HF)

Clinical TrialMentor · Awarded by American Heart Association · 2017 - 2019

Deep learning driven angiographic analysis to enhance evaluation of coronary artery stenosis

ResearchCo-Principal Investigator · Awarded by Vigilant Medical · 2018 - 2019

NIR-TRAKS

Clinical TrialPrincipal Investigator · Awarded by Medinol USA · 2015 - 2018

CardioMEMS

Clinical TrialMentor · Awarded by Pacesetter, Inc. · 2016 - 2018

Coronary Orbital Atherectomy System Trial

Clinical TrialPrincipal Investigator · Awarded by Cardiovascular Systems Inc. · 2014 - 2017

Procyrion FIM Device Study

ResearchPrincipal Investigator · Awarded by Procyrion, Inc. · 2016 - 2017

CSI Educational Program Agreement VI

ConferencePrincipal Investigator · Awarded by Cardiovascular Systems Inc. · 2016 - 2017

Patient-centered Outcomes Related to Treatment practices in peripheral Arterial disease: an International Trajectory

ResearchPrincipal Investigator · Awarded by Saint Luke's Hospital (Kansas City) · 2012 - 2016

PROMISE Trial: Clinical Coordinating Center

Clinical TrialCo Investigator · Awarded by National Institutes of Health · 2009 - 2016

CSI Educational Program Agreement VII

ConferencePrincipal Investigator · Awarded by Cardiovascular Systems Inc. · 2016 - 2016

PROMISE Trial: SDCC

Clinical TrialInvestigator · Awarded by National Institutes of Health · 2009 - 2015

CSI Educational Program Agreement IV

ConferencePrincipal Investigator · Awarded by Cardiovascular Systems Inc. · 2015 - 2015

CSI Educational Program Agreement

ConferencePrincipal Investigator · Awarded by Cardiovascular Systems Inc. · 2014 - 2014

TO # 1 - Coordinating Center for Cardiovascular Disease - OPTION YEAR 2

ResearchInvestigator · Awarded by Agency for Healthcare Research and Quality · 2011 - 2013

TO # 1 - Coordinating Center for Cardiovascular Disease

ResearchInvestigator · Awarded by Agency for Healthcare Research and Quality · 2010 - 2011

External Relationships


  • Bayer Healthcare Pharmaceuticals
  • Bionic Health
  • Cohere Med
  • HealthForce
  • Heartflow
  • Bayer Healthcare Pharmaceuticals
  • Bionic Health
  • Cohere Med
  • HealthForce
  • Heartflow
  • Janssen Pharmaceuticals (Johnson & Johnson)
  • Novartis pharmaceuticals
  • Vascular Cures
  • WebMD/Medscape

This faculty member (or a member of their immediate family) has reported outside activities with the companies, institutions, or organizations listed above. This information is available to institutional leadership and, when appropriate, management plans are in place to address potential conflicts of interest.