Mara Serbanescu

Journal article Curr Opin Crit Care · August 1, 2026 PURPOSE OF REVIEW: Microbial translocation has long been viewed as a nonspecific consequence of gut barrier failure in critical illness, with downstream effects attributed primarily to the host immune response. This review examines emerging evidence that t ... Full text Link to item Cite

Effects of Perioperative Exposure on the Microbiome and Outcomes From an Immune Challenge in C57Bl/6 Adult Mice.

Journal article Anesth Analg · January 1, 2026 BACKGROUND: Previous work suggests that the gut microbiome can be disrupted by antibiotics, anesthetics, opiates, supplemental oxygen, or nutritional deprivation-all of which are common and potentially modifiable perioperative interventions that nearly all ... Full text Link to item Cite

Impact of fiber-containing enteral nutrition on microbial community dynamics in critically ill trauma patients: a pilot-randomized trial.

Journal article BMC Med · December 29, 2025 BACKGROUND: Gut microbial dysbiosis is common in the intensive care unit and certain derangements, like expansion of Enterobacteriaceae and other potential pathogens (pathobionts), are associated with increased morbidity. In other populations, dysbiosis is ... Full text Link to item Cite

Recent Insights into the Evolving Role of the Gut Microbiome in Critical Care.

Journal article Crit Care Clin · April 2025 This review explores the evolving understanding of gut microbiota's role in critical illness, focusing on how acute illness and exposures in intensive care unit (ICU) environment negatively impact the gut microbiota and the implications of these changes on ... Full text Link to item Cite

Role of Resident Microbial Communities in Biofilm-Related Implant Infections: Recent Insights and Implications.

Journal article Surg Infect (Larchmt) · April 2023 The use of medical implants continues to grow as the population ages. Biofilm-related implant infection is the leading cause of medical implant failure and remains difficult to diagnose and treat. Recent technologies have enhanced our understanding of the ... Full text Link to item Cite

Impact of Intensive Care Unit Nutrition on the Microbiome and Patient Outcomes.

Journal article Anesthesiol Clin · March 2023 The bipartite relationship between nutrition and the intestinal microbiome represents an exciting frontier in critical care medicine. In this review, the authors first address these topics independently, leading with a summary of recent clinical studies as ... Full text Link to item Cite

The Epiaortic Ultrasound Diagnosis of Iatrogenic Subadventitial Hematoma.

Journal article A A Pract · November 2020 Iatrogenic aortic injury is a rare but potentially lethal complication of cardiac surgery. While sometimes resulting in aortic dissection or intramural hematoma, injury more frequently results in subadventitial hematoma, a more benign pathology. Here, we d ... Full text Link to item Cite

General Anesthesia Alters the Diversity and Composition of the Intestinal Microbiota in Mice.

Journal article Anesth Analg · October 2019 Dysbiosis of the intestinal microbiota has been shown to result in altered immune responses and increased susceptibility to infection; as such, the state of the intestinal microbiome may have profound implications in the perioperative setting. In this firs ... Full text Link to item Cite

Blood utilization and mortality in victims of gun violence.

Journal article Transfusion · October 2018 BACKGROUND: Blood transfusion can be lifesaving for patients with hemorrhage; however, transfusion requirements for victims of gun violence are poorly understood. STUDY DESIGN AND METHODS: In an urban, Level 1 trauma center, 23,422 trauma patients were ana ... Full text Link to item Cite

Epidural Abscess in Lemierre׳s Syndrome.

Journal article Am J Med Sci · September 2017 Full text Link to item Cite

Attrition of memory CD8 T cells during sepsis requires LFA-1.

Journal article J Leukoc Biol · November 2016 CD8 T cell loss and dysfunction have been implicated in the increased susceptibility to opportunistic infections during the later immunosuppressive phase of sepsis, but CD8 T cell activation and attrition in early sepsis remain incompletely understood. Wit ... Full text Link to item Cite

Chronic Alcohol Ingestion Delays T Cell Activation and Effector Function in Sepsis.

Journal article PLoS One · 2016 Sepsis is the leading cause of death in intensive care units in the US, and it is known that chronic alcohol use is associated with higher incidence of sepsis, longer ICU stays, and higher mortality from sepsis. Both sepsis and chronic alcohol use are asso ... Full text Link to item Cite