ConferenceEuropean Heart Journal · November 5, 2025
AbstractBackgroundPrevious studies have linked the HeartLogic index to heart failure (HF) decompensation, but have primarily fo ...
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ConferenceEuropean Heart Journal · November 5, 2025
AbstractBackgroundThe burden of atrial fibrillation (AF) is high among patients with heart failure (HF), and it can be challeng ...
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ConferenceEuropean Heart Journal · November 5, 2025
AbstractBackgroundGlucagon-like peptide-1 receptor agonists (GLP-1 RAs) have emerged as effective antihyperglycemic agents with ...
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ConferenceCirculation · November 4, 2025
Introduction:
Despite significant support of the clinical benefits of GDMT, heart failure (HF) patients have poor clinical outcomes and as a result high healthcare costs and utilizatio ...
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ConferenceCirculation · November 4, 2025
Background:
Pulmonary capillary wedge pressure (PCWP) provides an objective assessment of congestion status in heart failure (HF) patients, but its use is limited by the need for an in ...
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ConferenceCirculation · November 4, 2025
Background:
Heart failure with preserved ejection fraction (HFpEF) is a heterogeneous condition with high morbidity and mortality. Risk stratification of patients with HFpEF is importa ...
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ConferenceAm Heart J · November 2025
BACKGROUND: In the PARAGLIDE-HF trial, treatment with sacubitril/valsartan (Sac/Val) was associated with greater reduction in NT-proBNP than valsartan (Val) alone in patients stabilized after an episode of worsening heart failure (HF) with left ventricular ...
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ConferenceAm Heart J · November 2025
BACKGROUND: PARAGLIDE-HF showed significantly greater reduction in NT-proBNP in patients with LVEF>40% and worsening HF with sacubitril/valsartan (sac/val) vs valsartan (val). The impact of structural abnormalities on the effects of sac/val in this context ...
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ConferenceCirculation Heart Failure · October 1, 2025
BACKGROUND: – The atria play an important role in the pathophysiology of heart failure with preserved ejection fraction. Decreased left atrial strain is associated with worse clinical outcomes. The impact of no-implant interatrial shunting on atrial struct ...
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ConferenceFrontiers in Cardiovascular Medicine · January 1, 2025
Ex vivo machine perfusion has been growing in utility for preserving donor organs prior to transplantation. This modality has tremendous potential for bioengineering and conditioning organs prior to transplantation using small molecule or advanced therapeu ...
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ConferenceCirculation · November 12, 2024
Background:
Growing evidence supports a therapeutic role for ketones in HFrEF. However, no pharmacokinetic (PK) studies are available to guide further investigation, and uncertainty exists regarding u ...
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ConferenceCirculation · November 12, 2024
Background:
Hospitalizations due to heart failure (HF) are costly and detrimental to patient health. The HeartLogic (HL) algorithm has been found to be predictive of impending HF decompensation.
...
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ConferenceCirculation · November 12, 2024
Background:
Beta-blockers (BB) and non-dihydropyridine calcium channel blockers (CCB) are first-line therapies for hypertrophic cardiomyopathy (HCM) used both upon symptom onset and for pre-symptomati ...
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ConferenceCirculation · November 12, 2024
Background:
Understanding the natural history and factors contributing to heterogeneous outcomes in patients with early-stage hypertrophic cardiomyopathy (HCM) is crucial to improving patient manageme ...
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ConferenceEuropean Heart Journal · October 28, 2024
AbstractIntroductionRemote monitoring using an implantable pulmonary artery pressure (PAP) sensor (CardioMEMS HF system) in patients w ...
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ConferenceCirculation · November 7, 2023
Introduction:
Heart failure (HF) patients experience unnecessary morbidity and mortality due to inadequate use and dose of GDMT. While RPM has proven to help HFrEF patients achieve higher rates of GDM ...
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ConferenceCirculation · November 7, 2023
Background:
The changes in RV function after LVAD placement are not fully understood. RV- PA coupling, defined as the ratio of RV end-systolic to arterial elastances (E
ES
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ConferenceCirculation · November 7, 2023
Background
Advanced hepatic fibrosis (AHF) is associated with cardiac remodeling and adverse outcomes in patients with coronary artery disease (CAD). The mechanistic basis of this relationship and the ...
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ConferenceCirculation · November 7, 2023
Introduction:
Traditional methods for diagnosing and treating HTN, which is the most common modifiable risk factor accounting for ASCVD in the US, have been ineffective. Innovative solutions, like rem ...
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ConferenceCirculation · November 7, 2023
Introduction:
Non-alcoholic fatty liver disease (NAFLD) is associated with heart failure with preserved ejection fraction (HFpEF), independent of shared risk factors. The aim of this study was to dete ...
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ConferenceCirculation · November 7, 2023
Background:
Hemodynamic Frontiers in Heart Failure (HF
2
) is a multicenter research consortium of institutions with active remote pulmonary artery pressur ...
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ConferenceCirculation · November 7, 2023
Background:
Primary prevention strategies to reduce heart failure (HF) burden are urgently warranted. The Pooled Cohort equations to Prevent HF (PCP-HF) risk score is a validated risk tool that integr ...
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ConferenceCirculation · November 7, 2023
Background:
The prognostic value of heart rate variability (HRV) in Black Americans (BAs), who have distinct cardiac risk profiles, is not well studied. We aimed to investigate the association between ...
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ConferenceSLEEP · May 29, 2023
AbstractIntroductionGiven conflicting evidence in the literature, we sought to evaluate the relative importance of central sleep apnea ...
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ConferenceSci Rep · January 6, 2023
Socioeconomic status is an overlooked risk factor for cardiovascular disease (CVD). Low family income is a measure of socioeconomic status and may portend greater CVD risk. Therefore, we assessed the association of family income with cardiovascular risk fa ...
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ConferenceProceedings of Machine Learning Research · January 1, 2023
Global access to statistically and clinically representative patient health data holds potential for advancing disease research, enhancing patient care, and accelerating drug development. However, acquisition of health data such as electronic health record ...
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ConferenceEur J Heart Fail · November 2022
AIMS: We aimed to investigate the impact of obstructive coronary artery disease (CAD) in patients with acute decompensated heart failure (ADHF), and examine potential differences in prognostic utility for heart failure with reduced (HFrEF) versus preserved ...
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ConferenceInternational Conference on Architectural Support for Programming Languages and Operating Systems ASPLOS · February 22, 2022
We propose a new system design for connecting hardware and FPGA accelerators to the network, allowing the accelerator to directly control commodity Network Interface Cards (NICs) without using the CPU. This enables us to solve the key challenge of leveragi ...
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ConferenceMedical Research Archives · 2022
Background: Lung-impedance (LI) guided treatment of heart failure (HF) patients was shown to improve clinical outcomes. Objectives: To perform a post-hoc analysis of the IMPEDANCE-HF extended trial in order to explore the mechanism underlying the ...
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ConferenceJ Card Fail · March 2021
BACKGROUND: Venoarterial extracorporeal membrane oxygenation (VA-ECMO) is increasingly used as a life-saving therapy for patients with cardiovascular collapse, but identifying patients unlikely to benefit remains a challenge. METHODS AND RESULTS: We create ...
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ConferenceJACC Cardiovasc Imaging · July 2019
OBJECTIVES: The goal of this study was to examine whether diastolic dyssynchrony, measured by using gated single-photon emission computed tomography (GSPECT) myocardial perfusion imaging (MPI) in patients with coronary artery disease (CAD), is independentl ...
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ConferenceJ Am Heart Assoc · December 18, 2018
Background We sought to study the prevalence of high-sensitivity troponin and its association with cardiac structure and outcomes in ambulatory and hospitalized patients with heart failure with a preserved ejection fraction ( HF p EF ). Methods and Results ...
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