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Mariam Kayle

Associate Professor in the School of Nursing
School of Nursing
DUMC 3322, 307 Trent Dr.,, Duke University School of Nursing, Durham, NC 27710
307 Trent Dr, Durham, NC 27710

Overview


Dr. Kayle’s program of research aims to improve health outcomes among people with childhood-onset complex chronic conditions, with a focus on sickle cell disease (SCD). In partnership with the North Carolina Department of Health and Human Services, Division of Public Health, she co-leads the North Carolina Sickle Cell Data Collection Program (NC SCDC), a state-level surveillance program funded by the Centers for Disease Control and Prevention. NC SCDC curates and analyzes multi-source, population-level datasets to describe the epidemiology, health outcomes, and social determinants of health influencing SCD. Dr. Kayle collaborates with national and state partners to disseminate surveillance findings informing practice, research, and policy for SCD.

Dr. Kayle teaches and mentors students enrolled in the Doctor of Nursing Practice (DNP) and the Doctor of Philosophy in Nursing (PhD) programs at the School of Nursing. Her service contributions include several state and national committees on SCD.

Dr. Kayle completed her Bachelor of Science in Nursing at the American University of Beirut, her Master's in Pediatric Acute and Critical Care and her Doctor of Philosophy in Nursing at Duke University School of Nursing, and her Postdoctoral Fellowship in Health Services and Outcomes Research at Northwestern University, Feinberg School of Medicine. She has over twelve years of pediatric acute and critical care clinical experience, including six years in hospital administration and quality improvement. 

Current Appointments & Affiliations


Associate Professor in the School of Nursing · 2024 - Present School of Nursing

In the News


Published June 20, 2025
Emergency Visit Barriers for Sickle Cell Patients
Published November 13, 2024
n one of NC’s top counties for sickle cell, treatment is hard to come by
Published November 30, 2020
Kayle Meets with Congressional Staff on the NC Sickle Cell Program, Duke Health Government Relations

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Recent Publications


Acute Care Use Among People With Sickle Cell Disease, Sickle Cell Data Collection Program, 8 US States, 2018.

Journal Article Public health reports (Washington, D.C. : 1974) · November 2025 ObjectivesUnderstanding patterns of hospital admissions and emergency department (ED) visits among people with sickle cell disease is critical for improving care and access to care for this population. The objective of this study was to characteri ... Full text Open Access Cite

Pregnancy- and Disease-Related Morbidity Among Medicaid Enrollees With Sickle Cell Disease.

Journal Article Pediatric blood & cancer · September 2025 BackgroundWhereas pregnancy in sickle cell disease (SCD) is considered high risk, there is limited understanding of pregnancy- and SCD-related morbidity to inform clinical practice and health policy.ProcedureThis retrospective cohort stud ... Full text Cite

Redefining High Emergency Department Utilization for Sickle Cell Disease.

Journal Article JAMA Netw Open · June 2, 2025 IMPORTANCE: Sickle cell disease (SCD) is a complex hemoglobinopathy. Vaso-occlusive episodes are the primary cause of emergency department (ED) utilization among individuals with SCD. Literature lacks a standardized definition for high ED utilization. OBJE ... Full text Link to item Cite
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Recent Grants


North Carolina Sickle Cell Data Collection

Public ServicePrincipal Investigator · Awarded by NC Department of Health and Human Services · 2024 - 2024

NCDHHS Sickle Cell Data Collection Program in North Carolina Year 3

Public ServicePrincipal Investigator · Awarded by NC Department of Health and Human Services · 2022 - 2023

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Education, Training & Certifications


Duke University · 2017 Ph.D.
Duke University · 2005 M.S.N.