Scholars@Duke
Mariam Kayle

Mariam Kayle

Associate Professor in the School of Nursing
School of Nursing
mariam.kayle@duke.edu
DUMC 3322, 307 Trent Dr.,, Duke University School of Nursing, Durham, NC 27710
307 Trent Dr, Durham, NC 27710

Scholarly Works - Journal articles

Patterns of emergency department utilization among persons with multiple sclerosis across seven medical institutions.

Journal article Multiple sclerosis and related disorders · May 2026 BackgroundPersons with multiple sclerosis (MS) rely heavily on the emergency department (ED) for acute care, with marginalized populations bearing an unequal MS burden of disease. Understanding how social determinants of health influence ED utiliz ... Full text Cite

Acute Care Use Among People With Sickle Cell Disease, Sickle Cell Data Collection Program, 8 US States, 2018.

Journal article Public health reports (Washington, D.C. : 1974) · March 2026 ObjectivesUnderstanding patterns of hospital admissions and emergency department (ED) visits among people with sickle cell disease is critical for improving care and access to care for this population. The objective of this study was to characteri ... Full text Open Access Cite

A public health led, statewide approach to improving emergency department care for individuals with sickle cell disease—North Carolina

Journal article Journal of Sickle Cell Disease · January 1, 2026 Sickle cell disease (SCD) is a lifelong condition affecting approximately 100 000 individuals in the United States. It causes progressive organ damage through hemolysis, vaso-occlusion, and chronic inflammation. Patients frequently present to emergency dep ... Full text Cite

Trajectories of emergency department use among adolescents and young adults with sickle cell disease in North Carolina

Journal article Journal of Sickle Cell Disease · January 1, 2026 Objectives: Emergency department (ED) utilization among transition age adolescents and young adults (AYAs, 14-30 years old) with SCD is linked to morbidity and mortality. We describe age-related ED utilization and associations with sociodemographic charact ... Full text Cite

Pregnancy- and Disease-Related Morbidity Among Medicaid Enrollees With Sickle Cell Disease.

Journal article Pediatric blood & cancer · September 2025 BackgroundWhereas pregnancy in sickle cell disease (SCD) is considered high risk, there is limited understanding of pregnancy- and SCD-related morbidity to inform clinical practice and health policy.ProcedureThis retrospective cohort stud ... Full text Cite

Redefining High Emergency Department Utilization for Sickle Cell Disease.

Journal article JAMA Netw Open · June 2, 2025 IMPORTANCE: Sickle cell disease (SCD) is a complex hemoglobinopathy. Vaso-occlusive episodes are the primary cause of emergency department (ED) utilization among individuals with SCD. Literature lacks a standardized definition for high ED utilization. OBJE ... Full text Link to item Cite

Patterns and Predictors of Hydroxyurea Use Among Californians Living With Sickle Cell Disease.

Journal article Journal of pediatric hematology/oncology · May 2025 Hydroxyurea is the primary disease-modifying therapy for sickle cell disease (SCD), yet adherence is low. Our objective was to identify patterns and predictors of hydroxyurea adherence among Medicaid enrollees with SCD. Children and adults with SCD who rec ... Full text Cite

Gaps during pediatric to adult care transfer escalate acute resource utilization in sickle cell disease.

Journal article Blood Adv · July 23, 2024 Guidelines recommend transfer to adult health care within 6 months of completing pediatric care; however, this has not been studied in sickle cell disease (SCD). We hypothesized that longer transfer gaps are associated with increased resource utilization. ... Full text Link to item Cite

Birth Prevalence of Sickle Cell Disease and County-Level Social Vulnerability - Sickle Cell Data Collection Program, 11 States, 2016-2020.

Journal article MMWR Morb Mortal Wkly Rep · March 28, 2024 Sickle cell disease (SCD) remains a public health priority in the United States because of its association with complex health needs, reduced life expectancy, lifelong disabilities, and high cost of care. A cross-sectional analysis was conducted to calcula ... Full text Open Access Link to item Cite

Common data model for sickle cell disease surveillance: considerations and implications.

Journal article JAMIA Open · July 2023 OBJECTIVE: Population-level data on sickle cell disease (SCD) are sparse in the United States. The Centers for Disease Control and Prevention (CDC) is addressing the need for SCD surveillance through state-level Sickle Cell Data Collection Programs (SCDC). ... Full text Open Access Link to item Cite

Emergency department visits and hospitalizations among patients with sickle cell disease in illinois, 2016-2020.

Journal article Pediatric hematology and oncology · February 2023 Sickle cell disease (SCD) state level surveillance data are limited. We performed a retrospective review of emergency department (ED) visits and hospitalizations from individuals with SCD in Illinois (2016-2020) using the Illinois Health and Hospital Assoc ... Full text Cite

Longitudinal Trajectories of Clean Intermittent Catheterization Responsibility in Youths with Spina Bifida.

Journal article The Journal of urology · January 2022 PurposeClean intermittent catheterization (CIC) responsibility among youths with spina bifida is not well studied. We sought to determine longitudinal trajectories of CIC responsibility to examine the transition of CIC responsibility from caregive ... Full text Cite

Patient-reported neurocognitive symptoms influence instrumental activities of daily living in sickle cell disease.

Journal article American journal of hematology · November 2021 Individuals with sickle cell disease (SCD) experience neurocognitive decline, low medication adherence, increased unemployment, and difficulty with instrumental activities of daily living (IADL). The relationship between self-perceived cognitive difficulti ... Full text Cite

Redesigning clinical education to transition pre-licensure students from all-virtual to in-person clinical

Journal article Teaching and Learning in Nursing · July 1, 2021 At the start of the COVID-19 pandemic, pre-licensure nursing programs swiftly adapted the curriculum to accommodate the cessation of in-person clinical and transition to all-virtual clinical education. Once in-person clinical resumed, a re-design of clinic ... Full text Cite

Predictors of Distinct Trajectories of Medical Responsibility in Youth with Spina Bifida.

Journal article Journal of pediatric psychology · November 2020 ObjectiveTo determine if there are distinct developmental trajectories of medical responsibility in youth with spina bifida (SB) across ages 8-17 years and to identify condition-related, parental, and family systems predictors of membership in the ... Full text Cite

Impact of Medicaid expansion on access and healthcare among individuals with sickle cell disease.

Journal article Pediatric blood & cancer · May 2020 PurposeSickle cell disease (SCD) is associated with high acute healthcare utilization. The purpose of this study was to examine whether Medicaid expansion in California increased Medicaid enrollment, increased hydroxyurea prescriptions filled, and ... Full text Cite

Transition to adult care in sickle cell disease: A longitudinal study of clinical characteristics and disease severity.

Journal article Pediatr Blood Cancer · January 2019 BACKGROUND: Sickle cell disease (SCD) is a chronic blood disorder in which mortality has increased for adolescents and young adults (AYA). PROCEDURE: A longitudinal analysis of medical records was conducted to describe the clinical course among AYAs (ages ... Full text Link to item Cite

Evaluation of a Sickle Cell Disease Educational Website for Emergency Providers.

Journal article Advanced emergency nursing journal · April 2016 Sickle cell disease (SCD) is a complex multisystem debilitating disease. Despite its complexity, health care providers who are not SCD experts receive little formal education on SCD. An open-access, educational website, "Emergency Department Sickle Cell Di ... Full text Cite

Challenges in Shifting Management Responsibility From Parents to Adolescents With Sickle Cell Disease.

Journal article J Pediatr Nurs · 2016 UNLABELLED: This study explored the challenges faced by adolescents with sickle cell disease (SCD) and their parents and the work they engage in to progressively shift from parent management to independent adolescent self-management. DESIGN AND METHODS: A ... Full text Link to item Cite

The Adolescent and Young Adult with Cancer: A Developmental Life Course Perspective.

Journal article Semin Oncol Nurs · August 2015 OBJECTIVES: Using a Life Course Health Development framework, this article summarizes what is known about the impact of cancer and its treatment on the biopsychosocial world of the adolescent and young adult. DATA SOURCES: Published peer reviewed literatur ... Full text Link to item Cite

Attitudes toward patients with sickle cell disease in a multicenter sample of emergency department providers.

Journal article Advanced emergency nursing journal · October 2014 Patients with sickle cell disease (SCD) often seek care in the emergency department (ED) for pain associated with vaso-occlusive crises. Research has shown that negative provider attitudes serve as a barrier to care in this patient population. Our aim was ... Full text Cite

Survival at the threshold of viability: a nationwide survey of the opinions and attitudes of physicians in a developing country.

Journal article Paediatric and perinatal epidemiology · May 2014 BackgroundTo explore physicians' opinions and attitudes regarding resuscitation of extremely premature infants (EPIs) in a developing country with suboptimal resources.MethodsA survey was developed, revised, and pilot-tested. All 964 paed ... Full text Cite