Marianne Chanti-Ketterl

Journal article Alzheimers Dement · January 2026 INTRODUCTION: Volunteering is linked to cognitive benefits in aging, but evidence in diverse populations is limited. METHODS: We examined volunteering and cognition in Kaiser Healthy Aging and Diverse Life Experiences Study/Study of Healthy Aging in Africa ... Full text Open Access Link to item Cite

Modeling the importance of life exposure factors on memory performance in diverse older adults: A machine learning approach.

Journal article Alzheimers Dement · August 2025 INTRODUCTION: Many health life exposure factors (LEFs) influence cognitive decline and dementia incidence, but their relative importance to episodic memory (an early indicator of cognitive decline) among diverse older adults is unclear. We used machine lea ... Full text Open Access Link to item Cite

Ethnic and Sex Differences in the Association Between Organochlorine Exposure and Cognitive Function in Late Life.

Journal article J Gerontol A Biol Sci Med Sci · March 28, 2025 BACKGROUND: Organochlorine pesticides persist in the environment and body for extended periods. However, little is known about their long-term impact on cognition in older adults and if their influence differs by race/ethnicity (hereinafter ethnicity) and ... Full text Link to item Cite

Clinical Manifestations

Journal article Alzheimer's & dementia : the journal of the Alzheimer's Association · December 1, 2024 BACKGROUND: Neurocognitive health is influenced by multiple modifiable and non-modifiable lifestyle factors. Machine learning tools offer a promising approach to better understand complex models of cognitive function. We used extreme gradient boosting (XG ... Full text Cite

An Early and Unequal Decline: Life Course Trajectories of Cognitive Aging in the United States.

Journal article J Aging Health · March 2024 Objectives: Cognitive aging is a lifelong process with implications for Alzheimer's disease and dementia. This study aims to fill major gaps in research on the natural history of and social disparities in aging-related cognitive decline over the life span. ... Full text Link to item Cite

Associations Between Traumatic Brain Injury and Cognitive Decline Among Older Male Veterans: A Twin Study.

Journal article Neurology · October 31, 2023 BACKGROUND AND OBJECTIVES: Traumatic brain injuries (TBIs) are associated with increased risk of dementia, but whether lifetime TBI influences cognitive trajectories in later life is less clear. Cognitive interventions after TBI may improve cognitive traje ... Full text Open Access Link to item Cite

The Preventing Alzheimer's with Cognitive Training (PACT) randomized clinical trial.

Journal article Contemp Clin Trials · December 2022 BACKGROUND: To address the rising prevalence of Alzheimer's disease and related dementias, effective interventions that can be widely disseminated are warranted. The Preventing Alzheimer's with Cognitive Training study (PACT) investigates a commercially av ... Full text Link to item Cite

Traumatic brain injury and dementia risk in male veteran older twins-Controlling for genetic and early life non-genetic factors.

Journal article Alzheimers Dement · November 2022 INTRODUCTION: This study leveraged the twin study design, which controls for shared genetic and early life exposures, to investigate the association between traumatic brain injury (TBI) and dementia. METHODS: Members of the National Academy of Sciences-Nat ... Full text Link to item Cite

Sex Differences in the Association Between Metabolic Dysregulation and Cognitive Aging: The Health and Retirement Study.

Journal article J Gerontol A Biol Sci Med Sci · September 1, 2022 BACKGROUND: Dysregulation of some metabolic factors increases the risk of dementia. It remains unclear if overall metabolic dysregulation, or only certain components, contribute to cognitive aging and if these associations are sex specific. METHODS: Data f ... Full text Link to item Cite

Life-course trajectories of body mass index from adolescence to old age: Racial and educational disparities.

Journal article Proc Natl Acad Sci U S A · April 27, 2021 No research exists on how body mass index (BMI) changes with age over the full life span and social disparities therein. This study aims to fill the gap using an innovative life-course research design and analytic methods to model BMI trajectories from ear ... Full text Link to item Cite

Racially diverse participant registries to facilitate the recruitment of African Americans into presymptomatic Alzheimer's disease studies.

Journal article Alzheimers Dement · August 2020 INTRODUCTION: The Alzheimer's Disease Prevention Registry (ADPR) of the Joseph and Kathleen Bryan Alzheimer's Disease Research Center at Duke University has been successful in achieving a racially diverse and "research ready" cohort of cognitively healthy ... Full text Link to item Cite

The NAS-NRC Twin Registry and Duke Twins Study of Memory in Aging: An Update.

Journal article Twin Res Hum Genet · December 2019 The National Academy of Sciences-National Research Council (NAS-NRC) Twin Registry is one of the oldest, national population-based twin registries in the USA. It comprises 15,924 White male twin pairs born in the years 1917-1927 (N = 31.848), both of whom ... Full text Link to item Cite

The Association Between Lipoproteins, Disability, and Physical Function Among Older Costa Rican Adults.

Journal article J Aging Health · June 2018 OBJECTIVE: To examine the relationship between total cholesterol (TC), triglycerides (TG), and high-density lipoprotein cholesterol (HDL-C) with disability and physical performance. METHOD: Wave 1 data were from Costa Rican Longevity and Healthy Aging Stud ... Full text Link to item Cite

The Impact of Multiple Dimensions of Socioeconomic Status on Physical Functioning Across the Life Course.

Journal article Gerontol Geriatr Med · 2018 Objective: We used the Physical Performance Across the LifeSpan Study to investigate the relationships of multiple indicators of socioeconomic status (SES), both in early life and late life, with physical function. Method: We examined associations between ... Full text Open Access Link to item Cite

The relationship between phytoestrogens and speed of processing.

Journal article Menopause · August 2016 OBJECTIVE: This study examined the cross-sectional association between phytoestrogens and speed of processing. We hypothesized that higher levels of phytoestrogens would be related to better cognitive performance among older women. METHODS: Participants we ... Full text Link to item Cite

Cholesterol and cognitive performance among community volunteers from the Czech Republic.

Journal article Int Psychogeriatr · December 2015 BACKGROUND: Research shows that lipid levels may be associated with cognitive function, particularly among women. We aimed to examine total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), triglycerides (TG), high-density lipoprotein (HDL), a ... Full text Link to item Cite

Dementia: a barrier to receiving percutaneous coronary intervention for elderly patients with ST-elevated myocardial infarction.

Journal article Int J Geriatr Psychiatry · September 2014 OBJECTIVE: Percutaneous coronary intervention (PCI) is the first line of treatment for ST-elevated myocardial infarction (STEMI). This study evaluates the role of dementia in diagnostic cardiac catheterization (to receive PCI) in STEMI patients ≥65 years o ... Full text Link to item Cite