Journal articlePediatric blood & cancer · February 2025
BackgroundThe survival of children with Burkitt lymphoma (BL) in sub-Saharan Africa is disproportionately low compared to high-income countries. In Malawi, many of these children are diagnosed in advanced stages. Early and accurate diagnosis is cr ...
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Journal articleBlood advances · February 2025
AbstractThe spectrum of hematological diseases in African children includes anemias, bleeding disorders, thromboses, and oncological diseases such as leukemias. Although data are limited, outcomes for these diseases are poorer in Africa. The deart ...
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Journal articleJournal of pediatric hematology/oncology nursing · November 2023
Background: Symptoms in children with acute lymphocytic leukemia (ALL) change over the trajectory of treatment but little is known about their symptoms as treatment ends. Physical activity may help decrease symptom distress and is vital for ongoing ...
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Journal articlePediatric blood & cancer · November 2023
Chemotherapy-induced peripheral neuropathy (CIPN), a common condition in children with acute lymphoblastic leukemia, can be challenging to diagnose. Using data from Children's Oncology Group AALL0932 physical function study, we sought to determine if paren ...
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Journal articlePsycho-oncology · October 2022
ObjectiveThis study describes the prevalence of suicidal ideation (SI) during acute lymphoblastic leukemia (ALL) therapy and investigates the influence of clinical factors and physical symptoms on SI.MethodsThe Children's Depressive Inven ...
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Journal articleJournal of the National Cancer Institute · August 2022
BackgroundChildren with B-acute lymphoblastic leukemia (B-ALL) are at risk for chemotherapy-induced peripheral neuropathy (CIPN). Children's Oncology Group AALL0932 randomized reduction in vincristine and dexamethasone (every 4 weeks vs 12 weeks d ...
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Journal articleJournal of pain and symptom management · June 2022
ContextIn sub-Saharan Africa, there is no standardized approach to pediatric palliative care assessment. Because of this, there is a critical demand for evidence-based assessment tools that identify the specialized needs of children and their fami ...
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Journal articlePediatric blood & cancer · May 2022
BackgroundSurvivors of pediatric acute lymphoblastic leukemia (ALL) are at increased risk of neurocognitive weakness in the areas of attention, executive function, and processing speed. Although fatigue and sleep disturbances are frequent complica ...
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Journal articleCancer nursing · March 2022
BackgroundChildren undergoing treatment for acute lymphocytic leukemia (ALL) report co-occurring symptoms of fatigue, sleep disturbances, and depression as a symptom cluster. Physical activity (PA) may influence symptom severity and quality of lif ...
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Journal articleCancer nursing · November 2021
BackgroundDischarge education practices vary among institutions and lack a standardized approach for newly diagnosed pediatric oncology patients and their parents.ObjectiveThe purpose of this American Nurses Credentialing Center-supported ...
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Journal articleOncology nursing forum · November 2021
ObjectivesTo explore the relationship between biomarkers of oxidative stress and inflmmation in cerebrospinal fluid (CSF) and cognitive function in children receiving maintenance therapy for acute lymphocytic leukemia (ALL).Sample & setting
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Journal articleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · May 2021
PurposeDespite improvements in frontline pediatric acute lymphoblastic leukemia (ALL) treatment, relapse remains a concern. Research in adult cancer patients suggests that patient-reported symptoms may predict survival, but the relationship betwee ...
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Journal articleJournal of pain and symptom management · March 2021
ContextCancer-related fatigue (CRF) is one of the most distressing and persistent symptoms reported during pediatric acute lymphoblastic leukemia (ALL) therapy; however, information on the pathways underlying CRF severity is limited.Objectives ...
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Journal articleJournal of pediatric nursing · January 2021
PurposeTo change pediatric oncology nursing management of peripheral intravenous catheter (PIVC) insertion and care based on current best evidence.Design and methodsPractice change strategies were developed, and nurses completed education ...
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Journal articleInternational Journal of Africa Nursing Sciences · January 1, 2021
Purpose: The designation of the year 2020 as the International Year of the Nurse provides time for reflection on the importance of nursing in meeting the needs of the under-served throughout the world. The purpose of this project was to implement an educat ...
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Journal articleJournal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses · September 2020
Nursing specialization in the care of children with cancer provides the foundation for implementing successful childhood cancer and blood disorder treatment programs throughout the world. Excellence in nursing education is at the center of all that is need ...
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Journal articleJournal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses · July 2020
Background: During treatment for acute lymphoblastic leukemia (ALL), children report co-occurring symptoms of fatigue, sleep disturbance, pain, nausea, and depression as a symptom cluster. Central nervous system-directed ALL therapies also put child ...
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Journal articleJournal for specialists in pediatric nursing : JSPN · July 2020
Purpose/backgroundThe Parent Educational Discharge Support Strategies (PEDSS) nursing study includes 16 magnet pediatric oncology institutions across the United States and one in Saudi Arabia, evaluating a nurse-led parent educational discharge su ...
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Journal articleThe Journal of nursing administration · May 2020
Multisite study participation provides an opportunity for hospitals to gain access to the resources required to facilitate nursing research. The nurse-led Parent Educational Discharge Support Strategies for children newly diagnosed with cancer (PEDSS) mult ...
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Journal articleBiological research for nursing · October 2019
PurposeThe purpose of this study was to explore the influence of oxidative stress (F2-isoprostanes) and inflammatory (interleukin [IL]-8) biomarkers on symptom trajectories during the first 18 months of childhood leukemia treatment.Method ...
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Journal articleOncology nursing forum · July 2019
ObjectivesTo describe the impact of central nervous system-directed treatment on attention and its relation to academic outcomes in childhood acute lymphoblastic leukemia (ALL) survivors.Sample & setting51 children diagnosed with ALL ...
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Journal articleJournal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses · July 2019
Management of symptom-related distress is an important area of pediatric oncology nursing. Participants who attended the Children's Oncology Group (COG) State of the Science Symposium on symptom distress completed an anonymous survey. The purpose was to ex ...
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Journal articleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · May 2019
PurposeChronic pain, depression, and fatigue are common effects resulting from the cancer experience; new interventions are needed. This study examined the effect of Reimagine, an online symptom self-management curriculum that teaches coping skill ...
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Journal articleJournal of pediatric health care : official publication of National Association of Pediatric Nurse Associates & Practitioners · May 2019
IntroductionExamining the impact of appropriate sleep evaluation on diagnosis of attention deficit disorders can improve the standard of care in pediatrics. This quality improvement project examined current practice and subsequent implementation o ...
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Journal articleOncology nursing forum · March 2019
ObjectivesTo examine the relationship of the Childhood Cancer Symptom Cluster-Leukemia (CCSC-L) with health-related quality of life (HRQOL).Sample & setting327 children receiving treatment for acute lymphoblastic leukemia from four pediat ...
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Journal articleJournal of continuing education in nursing · March 2019
BackgroundAdvanced practice RNs (APRNs) make important contributions to scholarly journals that are derived from scientific evidence and clinical practice. This article presents a writing program designed to enhance the writing skills of APRNs wit ...
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Journal articleClinical journal of oncology nursing · February 2019
BackgroundTransitional care from inpatient to outpatient settings is a high-risk time for medical errors and missed follow-up appointments. Discharge checklists and handoffs are effective tools that lead to improved quality of care and outcomes.
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Journal articleCancer Nurs · 2019
BACKGROUND: Exercise outcome expectations (OEs) (ie, what one expects to obtain or avoid by exercising) are influential to increase exercise among cancer survivors. OBJECTIVE: The aim of this study was to measure the accessibility (ie, frequency one thinks ...
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Journal articleCancer nursing · November 2018
BackgroundChildren undergoing leukemia treatment report co-occurring symptoms of fatigue, sleep disturbances, pain, nausea, and depression as a symptom cluster. Physical activity (PA) is essential for development and may influence symptom severity ...
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Journal articlePsychooncology · October 2018
OBJECTIVE: The objective of the study is to test theoretical intervention fidelity and feasibility of MOVING ON, a self-directed, home-based, randomized controlled trial to increase exercise outcome expectations (OEs) (what one expects to obtain or avoid a ...
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Journal articleThe Lancet. Child & adolescent health · October 2018
Peripheral neuropathy is a well recognised treatment-related toxicity in children with cancer, associated with exposure to neurotoxic chemotherapy agents. Acute damage can occur in sensory, motor, or autonomic neurons, with symptoms that are rarely life th ...
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Journal articleClinical cancer research : an official journal of the American Association for Cancer Research · October 2018
Purpose: Methotrexate chemotherapy can be associated with neurologic complications during therapy and long-term neurologic deficits. This study evaluated demographic and clinical factors associated with incidence of methotrexate neurotoxicity and de ...
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Journal articleBiological research for nursing · July 2018
Aggressive central nervous system (CNS)-directed treatment for acute lymphoblastic leukemia (ALL), the most prevalent cancer among children and adolescents, prevents metastasis of leukemia cells into the brain. Up to 60% of survivors experience cognitive p ...
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Journal articleJournal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses · July 2018
Parents of children newly diagnosed with cancer must acquire new knowledge and skills in order to safely care for their child at home. Institutional variation exists in the methods and content used by nurses in providing the initial education. The goal of ...
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Journal articleBiological research for nursing · July 2018
The focus on a cure for childhood leukemia over the last three decades has resulted in survival rates of more than 80%. However, efforts to manage leukemia-treatment symptoms have not kept pace with new therapies. Symptom toxicity during treatment can resu ...
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Journal articleNurs Open · January 2018
AIM: The aim of this study was to test the feasibility and fidelity of an intervention, Moving On, aimed to increase outcome expectations OEs (i.e. what one expects to obtain or avoid as a result of a behaviour) and exercise among breast cancer survivors. ...
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Journal articleClinical journal of oncology nursing · August 2017
BackgroundPancreatic adenocarcinoma is an aggressive cancer that carries a poor prognosis. Pancreaticoduodenectomy (PD) offers the only potential cure, but the associated morbidity is high. The Enhanced Recovery After Surgery (ERAS) evidence-based ...
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Journal articleJournal of pain and symptom management · July 2017
ContextCancer treatment symptoms play a major role in determining the health of children with cancer. Symptom toxicity often results in complications, treatment delays, and therapy dose reductions that can compromise leukemia therapy and jeopardiz ...
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Journal articleJournal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses · November 2016
There is a paucity of data to support evidence-based practices in the provision of patient/family education in the context of a new childhood cancer diagnosis. Since the majority of children with cancer are treated on pediatric oncology clinical trials, la ...
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Journal articleJournal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses · November 2016
A diagnosis of childhood cancer is a life-changing event for the entire family. Parents must not only deal with the cancer diagnosis but also acquire new knowledge and skills to care safely for their child at home. Best practices for delivery of patient/fa ...
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Journal articleJournal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses · November 2016
Parents/caregivers require specialized education in order to care for their child with a newly diagnosed cancer. Currently, no evidence-based guidelines exist to identify content essential for inclusion in patient/family education prior to a child's initia ...
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Journal articleInternational Journal of Urological Nursing · November 1, 2016
Catheter-associated urinary tract infection (CAUTI) comprises 30–40% of all health care-acquired infections, and 70–80% of these infections are related with use of indwelling urinary catheters. This quality improvement (QI) project was initiated to evaluat ...
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Journal articleBiological research for nursing · October 2016
Fatigue is a frequent and distressing symptom in children undergoing leukemia treatment; however, little is known about factors influencing this symptom. Antioxidants such as glutathione can decrease symptom severity in adult oncology patients, but no stud ...
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Journal articleCancer nursing · July 2016
BackgroundAcute lymphoblastic leukemia is the most common pediatric cancer, and survival approaches 90%. Acute lymphoblastic leukemia survivors are more likely than healthy peers or siblings to experience academic underachievement, yet little is k ...
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Journal articleJournal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses · July 2016
Although traditional recommendations for mononephric childhood cancer survivors are to avoid contact sports in order to protect the remaining kidney, review of available evidence suggests that the majority of renal loss is caused by accidents not involving ...
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Journal articleNurse Educ · 2016
The growth in health professions education (HPE) and a desire on the part of nurse and medical educators to disseminate their work have raised important questions about the ethical conduct of education research. At the center of the debate is the instituti ...
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Journal articleClinical journal of oncology nursing · December 2015
Although many patients with gynecologic cancer undergo surgery, time constraints during the preoperative consultation may affect the accuracy of the information exchange, as well as compromise the quality of the patient assessment and care plan. Both put p ...
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Journal articleJournal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses · November 2015
Eliminating central line-associated bloodstream infection (CLABSI) is a national priority. Central venous catheter (CVC) care bundles are composed of a series of interventions that, when used together, are effective in preventing CLABSI. A CVC daily mainte ...
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Journal articleJournal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses · September 2015
Central nervous system (CNS) treatment is an essential part of acute lymphocytic leukemia (ALL) therapy, and the most common CNS treatment is intrathecal (IT) and high-dose intravenous (IV) methotrexate (MTX). Treatment with MTX may cause neurotoxicity, wh ...
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Journal articleJournal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses · September 2015
Health-related quality of life (HRQoL) has been noted to fluctuate among children during hematopoietic stem cell transplant (HSCT) recovery; however, the specific timing and associations of these changes are poorly understood. This repeated-measures study ...
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Journal articleJournal of pediatric hematology/oncology · August 2015
No widely accepted method exists to evaluate pediatric hematology oncology patients for the risk of venous thromboembolism (VTE) and the need for prophylaxis. The use of a VTE risk-assessment tool and standardized guidelines for prophylaxis could increase ...
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Journal articleOncology nursing forum · July 2015
Purpose/objectivesTo describe the trajectories of obesity/overweight rates by age group among survivors of childhood acute lymphoblastic leukemia (ALL) from diagnosis through several years post-therapy.DesignLongitudinal, descriptive. ...
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Journal articleJournal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses · July 2015
Chemotherapy-induced nausea and vomiting (CINV) is one of the most common side effects experienced by patients receiving chemotherapy. Antiemetic medications can be used to effectively prevent and treat CINV. Choice and dose of antiemetics are often based ...
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Journal articleJournal of pediatric hematology/oncology · March 2015
Five-year survival from childhood acute lymphoblastic leukemia (ALL) approaches 90%, but 40% of survivors experience central nervous system (CNS) treatment-related cognitive problems. Despite considerable evidence for cognitive problems, less is known abou ...
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Journal articleEuropean journal of oncology nursing : the official journal of European Oncology Nursing Society · February 2015
PurposeFatigue in childhood cancer is a pervasive and distressing symptom described as a "lack of energy". Carnitine is a micronutrient used to transport long chain fatty acids into muscle mitochondria. Some chemotherapy drugs interfere with the c ...
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Journal articleJournal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses · July 2014
This introduction article discusses the history and importance of evidence-based practice, along with describing the process that 6 nurse-led teams completed for the systematic reviews listed in this journal issue. ...
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Journal articleOncology nursing forum · July 2014
Purpose/objectivesTo explore the symptom trajectory during the first 16 months of childhood leukemia treatment and any associations with the oxidative stress pathway measured by cerebrospinal fluid (CSF) concentration of oxidized phosphatidylcholi ...
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Journal articleJournal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses · July 2014
Infections in children and adolescents with cancer are a significant cause of morbidity and mortality, especially in those receiving chemotherapy who are neutropenic and/or immunocompromised. The aim of this article is to review existing evidence in order ...
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Journal articleBiological research for nursing · July 2014
Acute lymphoblastic leukemia (ALL) is the most prevalent and curable cancer among children and adolescents less than 15 years of age in the United States. Essential for cure of childhood ALL is prophylactic treatment of the central nervous system (CNS), wi ...
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Journal articleOncology nursing forum · May 2014
Purpose/objectivesTo examine symptom reports and physiologic parameters in adolescents using the Eating After Transplant (EAT!) intervention during recovery after hematopoietic stem cell transplantation (HSCT).DesignRepeated measures desi ...
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Journal articleJ Pediatr Oncol Nurs · 2014
INTRODUCTION: This quality improvement (QI) project addresses a method for experienced health care providers to maintain skill-based competence for intrathecal access procedures. METHODS: A prospective QI design using intrathecal access simulation to asses ...
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Journal articleSeminars in oncology nursing · November 2013
ObjectivesTo summarize the current knowledge about 1) cognitive changes associated with central nervous system-directed chemotherapy and cranial radiation among children with acute lymphoblastic leukemia and brain tumors and adult survivors; and 2 ...
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Journal articleCancer nursing · September 2013
BackgroundAdolescents undergoing a hematopoietic stem cell transplantation (HSCT) experience a variety of adverse effects and eating difficulties. Few interventions exist to assist patients with self-care after HSCT hospitalization. The Eating Aft ...
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Journal articleCurrent opinion in supportive and palliative care · March 2013
Purpose of reviewResearchers have focused on identifying and describing symptom experiences among children with various diseases but symptoms can have a synergistic and/or an antecedent effect that must be evaluated. This review reports the curren ...
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Journal articlePediatric blood & cancer · August 2012
BackgroundDespite evidence that CNS treatment is associated with cognitive and academic impairment, interventions to prevent or mitigate these problems are limited. The purpose was to determine if early intervention can prevent declines in mathema ...
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Journal articleLeukemia & lymphoma · August 2012
Long-term survivors of childhood leukemia are at risk for neurocognitive impairment, although the neurophysiological basis is not well understood. The purpose of this study was to explore associations between changes in cerebrospinal fluid (CSF) phospholip ...
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Journal articleJournal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses · July 2012
Time-sensitive medical care is essential for pediatric patients undergoing treatment for a hematologic or oncologic condition. Such patients commonly experience acute symptoms related to routine childhood illness and/or their underlying disease or therapy. ...
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Journal articleCancer nursing · May 2012
BackgroundChemotherapy-induced nausea and vomiting (CINV) are common adverse effects, but occurrences among pediatric oncology patients are not well documented.ObjectiveThe primary aim was to describe anticipatory, acute, and delayed CINV ...
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Journal articleOncology nursing forum · March 2012
Purpose/objectivesTo identify anticipatory, acute, and delayed chemotherapy-induced nausea and vomiting (CINV) frequency and coping strategies used among pediatric patients with cancer.DesignProspective, cohort design.SettingA pe ...
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Journal articleJournal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses · March 2012
Cardiovascular disease (CVD) is the leading cause of death among adults in the United States. CVD pathology, including abnormal lipid levels, may begin in childhood. Hematopoietic stem cell transplant (HSCT) survivors have increased risk of abnormal lipid ...
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Journal articleJournal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses · January 2012
A major children's cancer and hematology center established a Quality Transformation (QT) Core to develop and monitor empirical outcomes that demonstrate excellence in clinical care. The QT Core, based on the Institute of Medicine's domains of quality heal ...
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Journal articleOncology nursing forum · September 2011
Purpose/objectivesTo describe the prevalence, frequency, severity, and distress of multiple symptoms in hospitalized children with cancer and to examine the overall symptom scores and global distress in patients reporting nausea, pain, and fatigue ...
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Journal articleJournal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses · September 2011
Fatigue is one of the most common and distressing symptoms experienced by adolescents during and after treatment for cancer. The lack of reliable and valid instruments has prevented an accurate assessment of the trajectory of fatigue among adolescent oncol ...
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Journal articleJournal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses · September 2011
Despite knowing that pediatric cancer patients experience multiple concurrent symptoms, most research focuses on individual symptoms. This study is a secondary data analysis from previous research evaluating symptom clusters and carnitine plasma levels in ...
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Journal articleArts & Health · September 2011
The Arts in Medicine (AIM) program is an established, 13-year-old program in a major children's Cancer and Hematology Center that provides meaningful artistic opportunities to cancer patients and their families in inpatient and outpatient settings. We rep ...
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Journal articleJournal of pediatric hematology/oncology · March 2011
Children with cancer experience repeated invasive and painful medical procedures. Pain and distress does not decrease with repeated procedures and may worsen if pain is not adequately managed. In 1990, the first recommendations on the management of pain an ...
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Journal articlePediatrics · February 2011
BackgroundAcute chest syndrome (ACS) is a leading cause of hospitalization and death of children with sickle cell disease (SCD). An evidence-based ACS/SCD guideline was established to standardize care throughout the institution in February 2008. H ...
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Journal articleJournal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses · January 2011
This review presents a summary of the research literature related to the incidence and risk factors for chronic graft-versus-host disease in children following allogeneic hematopoietic stem cell transplantation. The range of incidence of chronic graft-vers ...
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Journal articleEuropean journal of cancer (Oxford, England : 1990) · July 2010
BackgroundDexamethasone contributes to high cure rates in paediatric acute lymphoblastic leukaemia (ALL) but significantly and adversely alters sleep and fatigue. Herein we explored three mechanisms (pharmacokinetics, serum albumin and pharmacogen ...
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Journal articleJournal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses · March 2010
Bone marrow transplant (BMT) is a common treatment option for adolescents with various diseases; however, the aggressive therapy often causes significant side effects that can lead to poor eating. There is little documentation of eating experiences and nec ...
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Journal articleJournal of pediatric hematology/oncology · March 2010
Neurobehavioral problems after chemotherapy treatment for pediatric acute lymphoblastic leukemia (ALL) have been a recent focus of investigation. This study extended previous research that suggested oxidative stress as a potential mechanism for chemotherap ...
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Journal articleJournal of pain and symptom management · March 2010
Fatigue is one of the most debilitating conditions associated with cancer and anticancer therapy. The lack of reliable and valid self-report instruments has prevented accurate assessment of fatigue in pediatric oncology patients. The purpose of this study ...
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Journal articleOncology nursing forum · January 2010
Purpose/objectivesTo examine the influence of the proposed symptom cluster of fatigue, nausea and vomiting, and sleep disturbances on clinical outcomes defined as behavior changes, depression, and performance status in children and adolescents bef ...
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Journal articlePediatric blood & cancer · October 2009
BackgroundNeurocognitive sequelae following treatment for pediatric acute lymphoblastic leukemia (ALL) has been reported in a significant proportion of survivors, including those treated only with chemotherapy. Early identification of children "at ...
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Journal articleJournal of pediatric hematology/oncology · September 2009
Fatigue is the most frequent symptom experienced by children/adolescents with cancer. One mechanism contributing to cancer-related fatigue involves abnormalities in adenosine triphosphate synthesis caused by carnitine deficiency. The purpose of this study ...
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Journal articleOncology nursing forum · March 2009
Purpose/objectivesTo determine whether a comprehensive educational program influenced the incidence of hub colonization of central venous catheters (CVCs) and bloodstream infection rates in children with cancer, to identify risk factors related to ...
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Journal articleJournal of trauma nursing : the official journal of the Society of Trauma Nurses · January 2009
There is increasing effort in promoting evidence-based practice (EBP) that supports the best possible care to patients and families. This article describes essential concepts for developing an environment of EBP and its implementation at a large pediatric ...
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Journal articleJournal of continuing education in nursing · January 2009
Nurses and allied health professionals have the unique opportunity to become empowered through evidence-based practice (EBP) to make significant differences in the lives of patients and their families. Best practices in patient care occur only when staff c ...
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Journal articleOncology nursing forum · May 2008
Purpose/objectivesTo identify growth patterns and gastrointestinal (GI) symptoms in pediatric patients during the first four months after hematopoietic stem cell transplantation (HSCT) and to assess whether an association exists between acute graf ...
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Journal articleBiological research for nursing · April 2008
Treatment advances, including central nervous system (CNS) treatment with methotrexate, have led to significant gains in disease-free survival from childhood acute lymphoblastic leukemia (ALL). However, methotrexate has been associated with neurological pr ...
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Journal articlePediatric nursing · January 2008
Spanish speaking children with cancer were asked to describe their pain during the previous week prior to an oncology clinic appointment. Data showed that 41% of the children were experiencing pain and the overall mean pain intensity rating among these chi ...
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Journal articleJournal of pain and symptom management · December 2007
Adolescents undergoing treatment for cancer rate fatigue as their most prevalent and intense cancer- and treatment-related effect. Parents and staff rate it similarly. Despite its reported prevalence, intensity, and distressing effects, cancer-related fati ...
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Journal articleCancer · November 2007
BackgroundDexamethasone improves the cure rate of childhood acute lymphoblastic leukemia (ALL) but causes physical and behavioral adverse events. The objective of the current study was to determine the effect of dexamethasone exposure on sleep and ...
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Journal articleJournal of pediatric hematology/oncology · August 2007
BackgroundImproved survival for children with acute lymphocytic leukemia (ALL) has allowed investigators to focus on the adverse or side effects of treatment and to develop interventions that promote cure while decreasing the long-term effects of ...
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Journal articleJournal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses · July 2007
This study examines the pain experiences of children with cancer during hospitalization. A descriptive design with repeated measures was used to describe the location, intensity, and quality of pain, pain medications, amount of pain relief, and perceptions ...
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Journal articleJournal of nursing care quality · July 2007
There is increasing effort in promoting evidence-based practice (EBP) that supports the best possible care to patients and families. This article describes essential concepts for developing an environment of EBP and its implementation at a large pediatric ...
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Journal articleJournal of pain and symptom management · June 2007
This prospective, two-site, randomized, controlled pilot study assessed the feasibility of an enhanced physical activity (EPA) intervention in hospitalized children and adolescents receiving treatment for a solid tumor or for acute myeloid leukemia (AML), ...
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Journal articleSeminars in oncology nursing · May 2007
ObjectivesTo discuss the symptoms of fatigue, sleep disturbance, and pain in children undergoing cancer treatment, and a framework for the clustering of these symptoms.Data sourcesPublished articles, research studies, and clinical experie ...
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Journal articleJournal of pediatric psychology · March 2007
ObjectiveTo compare the effects of two intravenous (IV) methotrexate (MTX) infusion protocols on cognitive function in children newly diagnosed with acute lymphoblastic leukemia (ALL).MethodsWe compared 19 children treated with 1 g/m(2) o ...
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Journal articleOncology nursing forum · March 2007
Purpose/objectivesTo describe nocturnal awakenings and sleep environment interruptions experienced by children and adolescents hospitalized for two to four days to receive chemotherapy and to assess the relationships among nocturnal awakenings, sl ...
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Journal articleJournal of clinical oncology : official journal of the American Society of Clinical Oncology · August 2006
PurposeTo evaluate the effects of once-weekly epoetin alfa (EPO) on health-related quality of life (HRQOL), hemoglobin (Hb), transfusions, and tolerability in children with cancer.MethodsAnemic patients 5 years to 18 years of age receivin ...
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Journal articlePediatric nursing · July 2006
A commonly stated reason for dissatisfaction among nurses is that their input regarding patient care and suggestions for improvement in the workplace environment are not solicited or recognized. Nurses can have an active voice in their practice by using th ...
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Journal articleJournal of clinical oncology : official journal of the American Society of Clinical Oncology · January 2006
Decision making in pediatric oncology can look different to the ethicist and the clinician. Popular ethical theories argue that clinicians should not make decisions for patients, but rather provide information so that patients can make their own decisions. ...
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Journal articleBiological research for nursing · January 2005
Central nervous system (CNS) treatment contributes to improved long-term disease-free survival from childhood acute lymphoblastic leukemia (ALL) by significantly decreasing the rate of disease relapse. Methotrexate (MTX), a drug commonly used for CNS treat ...
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Journal articleJournal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses · May 2004
A review of the clinical research studies published within the past 5 years revealed that efforts to manage symptoms of cancer and its treatments have not kept pace with new advances in the cure for cancer. Children with cancer continue to experience distr ...
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Journal articleOncology nursing forum · November 2003
Purpose/objectivesTo provide a brief description of the historic role of nursing and nursing research in the culture of previous pediatric oncology cooperative groups and compare the research language used in cooperative groups with the language u ...
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Journal articleJournal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses · November 2003
The diagnosis, treatment, and side effects of childhood cancer have been described as extremely stressful experiences in the life of a child. Anecdotally, children report that a sense of humor helps them cope with the daily experiences of living with cance ...
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Journal articleJournal of pediatric nursing · April 2003
We are pleased to publish this special issue on pediatric oncology nursing. The articles in this issue provide readers with the most current clinical updates on the treatment and care of children and youth with childhood cancer. We thank Dr. Marilyn Hocken ...
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Journal articleJournal of pain and symptom management · April 2003
The purpose of this study was to develop and test three instruments to measure fatigue in children with cancer from the perspectives of the child, parents and staff. The study consisted of three phases: instrument development, content validation, and estim ...
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Journal articleJournal of pediatric hematology/oncology · January 2002
Anemia is a hematologic abnormality commonly discussed during the treatment of childhood cancer, but its incidence has not been previously reported. As the basis for determining the incidence of anemia, this retrospective review of medical records combined ...
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Journal articleJournal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses · May 2001
Fatigue may be a universal experience for children and adolescents who are being treated for a malignancy. Sadly, it may also be the most unrecognized and thus unaddressed symptom experienced by this population. Giving adequate attention to this symptom ha ...
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Journal articleJournal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses · May 2001
Fatigue may be a universal experience for children and adolescents who are being treated for a malignancy. Sadly, it may also be the most unrecognized and thus unaddressed symptom experienced by this population. Giving adequate attention to this symptom ha ...
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Journal articleSeminars in oncology nursing · November 2000
OBJECTIVE: To describe the development of a research program focused on cancer-related fatigue in children and adolescents and the resulting definition and model. METHODS: Research studies, review articles, and clinical examples. CONCLUSIONS: Fatigue has b ...
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Journal articleCancer nursing · August 1999
Fatigue in children and adolescents with cancer is a disruptive symptom meriting clinical intervention by nurses, but has eluded definition, measurement, and intervention. Fatigue in these patients exists within a greater context of illness, treatment, and ...
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Journal articleOncology nursing forum · March 1999
OBJECTIVE: To document and analyze the perspectives of staff members who provide direct care to 7- to 12-year-old patients with cancer regarding the nature and characteristics of fatigue, causes of fatigue, and effective interventions for this population o ...
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Journal articleThe Journal of adolescent health : official publication of the Society for Adolescent Medicine · March 1999
OBJECTIVE: To identify the content, characteristics, and comfort level of discussions about sexuality held between mothers and their early adolescent children and to determine the extent to which the conversations predicted sexual values and initiation of ...
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Journal articleEuropean Journal of Oncology Nursing · March 1999
The purpose of this research study was to define fatigue experienced by children with cancer and to begin development of a conceptual model.Two major Paediatric Cancer Centers in the Southern USA participated in this study. Children who participated in thi ...
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Journal articleJournal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses · July 1998
Fatigue is a common symptom found in the adult oncology literature. However, little is known about its occurrence, causes, conceptual and operational definitions, and effective interventions in children and adolescents with cancer. The purpose of this stud ...
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Journal articleThe Pediatric infectious disease journal · October 1997
Fatigue is a common symptom found in the adult oncology literature. However, little is known about its occurrence, causes, conceptual and operational definitions, and effective interventions in children and adolescents with cancer. The purpose of this stud ...
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Journal articleJournal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses · July 1997
The childhood cancer literature provides limited understanding of the school-age child's perception of cancer stressors and factors that contribute to adjustment in the midst of these stressors. This study evaluated the reliability and validity of two ques ...
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Journal articleJournal of pediatric hematology/oncology · April 1997
OBJECTIVE: Despite improved event-free survival of older children with acute lymphocytic leukemia (ALL), infants 50,000/microl), and a higher likelihood of CD-10 (CALLA) negative lymphoblasts (55%). A translocation involving chromosome 11 at band q23 was d ...
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Journal articleJournal of Family Nursing · November 1996
Abstract: Using a focus group approach, the investigators sought to explore the role of African American mothers in the education of their adolescents about sexuality including the provision of factual information and transmission of values. A focus group ...
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Journal articleCancer · September 1996
OBJECTIVE: Despite improved event-free survival of older children with acute lymphocytic leukemia (ALL), infants 50,000/microl), and a higher likelihood of CD-10 (CALLA) negative lymphoblasts (55%). A translocation involving chromosome 11 at band q23 was d ...
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Journal articleCancer practice · August 1995
As part of a larger study on the impact of personal and family characteristics on adolescents' HIV risk and risk-reduction behavior, 90 adolescents and 73 mothers were asked to define in their own words seven terms related to sexual development: ejaculatio ...
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Journal articleCancer · May 1993
No abstract. Brief report on resource constraints on care of children with cancer in U.S., with recommendations on subjects such as access &U cost containment ...
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Journal articlePediatric nursing · May 1990
Treatment advances over the last few decades have dramatically increased survival for children with cancer. More than half the children treated for cancer are now cured. Consequently, professionals working with these children are beginning to focus on mini ...
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Journal articleCancer · March 1, 1989
The role of adjuvant chemotherapy for osteosarcoma has been well defined. Recently, the use of preoperative chemotherapy has been further enhanced by the use of intraarterial cisplatin. The authors describe the use and results of systemic doxorubicin and i ...
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Journal articleAm J Pediatr Hematol Oncol · 1989
Eighty-two patients, ranging in age from 11 months to 24 years, underwent the percutaneous placement of an implanted catheter in order to have improved venous access. Thirty-five patients (43%) were beginning chemotherapy for cancer, four (5%) had a chroni ...
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Journal articleSouthern medical journal · February 1987
We have reported the first case of isolated submucosal hematoma of the true vocal cord in a hemophilic patient. He was managed with factor VIII replacement therapy as an outpatient for five consecutive days, without complication. Similar but more serious c ...
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Journal articleThe Nursing clinics of North America · March 1985
Hypnosis, as a relaxation technique to reduce anxiety and drug-related nausea and vomiting in children with cancer, is an effective treatment modality. Its benefit as a self-relaxation technique is now being realized. ...
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