Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Fellow, Gastroenterology (Med) & Res. Fel. (Peds), Pediatrics, Children's Hospital, Boston 1975 - 1977
  • Fellow - Pediatric Gastroenterology, Pediatrics, University of Colorado at Colorado Springs 1974 - 1975
  • Resident, Pediatrics, University of Colorado at Colorado Springs 1972 - 1974
  • Intern, Medicine-Pediatrics, Medicine Pediatrics, North Carolina Memorial Hospital 1969 - 1970
  • M.D., University of Rochester 1969
• 

  Duke Appointment History

  • Professor of Pediatrics, Pediatrics, Gastroenterology, Hepatology and Nutrition, Pediatrics 2000 - 2014
  • Chief, Division of Pediatric Gastroenterology, Hepatology & Nutrition, Pediatrics, Gastroenterology, Hepatology and Nutrition, Pediatrics 2004 - 2014
  • Instructor, Temporary in the Department of Pediatrics, Pediatrics, Gastroenterology, Hepatology and Nutrition, Pediatrics 1999
• Research
• 

  Selected Grants

  • Biomarkers of Interoceptive Awareness in Adolescent Anorexia Nervosa awarded by National Institutes of Health 2009 - 2012
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Tilburg, Miranda A. L. van, Megan Squires, Nanette Blois-Martin, Cathy Williams, Marc A. Benninga, Babette Peeters, and Martin Ulshen. “Parental knowledge of fecal incontinence in children..” J Pediatr Gastroenterol Nutr 55, no. 3 (September 2012): 283–87. https://doi.org/10.1097/MPG.0b013e31824cf555.
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    • Greenberg, Rachel G., Cassandra Moran, Martin Ulshen, P Brian Smith, Daniel K. Benjamin, and Michael Cohen-Wolkowiez. “Outcomes of catheter-associated infections in pediatric patients with short bowel syndrome..” J Pediatr Gastroenterol Nutr 50, no. 4 (April 2010): 460–62. https://doi.org/10.1097/MPG.0b013e3181b99d07.
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    • Tilburg, Miranda A. L. van, Denesh K. Chitkara, Olafur S. Palsson, Marsha Turner, Nanette Blois-Martin, Martin Ulshen, and William E. Whitehead. “Audio-recorded guided imagery treatment reduces functional abdominal pain in children: a pilot study..” Pediatrics 124, no. 5 (November 2009): e890–97. https://doi.org/10.1542/peds.2009-0028.
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    • Tilburg, Miranda A. L. van, Neeta Venepalli, Martin Ulshen, Katherine L. Freeman, Rona Levy, and William E. Whitehead. “Parents' worries about recurrent abdominal pain in children..” Gastroenterol Nurs 29, no. 1 (January 2006): 50–55.
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    • Kader, Howard A., Wallace F. Berman, Amal S. Al-Seraihy, Russell E. Ware, Martin H. Ulshen, and William R. Treem. “Prevalence of factor V G1691A (Leiden), prothrombin G20210A, and methylene tetrahydrofolate reductase C677T thrombophilic mutations in children with inflammatory bowel disease..” J Pediatr Gastroenterol Nutr 35, no. 5 (November 2002): 629–35. https://doi.org/10.1097/00005176-200211000-00008.
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    • Worawattanakul, M., J. M. Rhoads, S. N. Lichtman, and M. H. Ulshen. “Abdominal migraine: prophylactic treatment and follow-up..” J Pediatr Gastroenterol Nutr 28, no. 1 (January 1999): 37–40. https://doi.org/10.1097/00005176-199901000-00010.
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    • Rittmeyer, C., D. Nakayama, and M. H. Ulshen. “Lymphoid hyperplasia causing recurrent rectal prolapse..” J Pediatr 131, no. 3 (September 1997): 487–88. https://doi.org/10.1016/s0022-3476(97)80086-8.
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    • Ohneda, K., M. H. Ulshen, C. R. Fuller, A. J. D’Ercole, and P. K. Lund. “Enhanced growth of small bowel in transgenic mice expressing human insulin-like growth factor I..” Gastroenterology 112, no. 2 (February 1997): 444–54. https://doi.org/10.1053/gast.1997.v112.pm9024298.
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    • Sävendahl, L., L. E. Underwood, K. M. Haldeman, M. H. Ulshen, and P. K. Lund. “Fasting prevents experimental murine colitis produced by dextran sulfate sodium and decreases interleukin-1 beta and insulin-like growth factor I messenger ribonucleic acid..” Endocrinology 138, no. 2 (February 1997): 734–40. https://doi.org/10.1210/endo.138.2.4941.
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    • Ulshen, M. H., and R. H. Raasch. “Luminal epidermal growth factor preserves mucosal mass of small bowel in fasting rats..” Clin Sci (Lond) 90, no. 5 (May 1996): 427–31. https://doi.org/10.1042/cs0900427.
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    • Hoyt, E. C., P. K. Lund, D. E. Winesett, C. R. Fuller, M. A. Ghatei, S. R. Bloom, and M. H. Ulshen. “Effects of fasting, refeeding, and intraluminal triglyceride on proglucagon expression in jejunum and ileum..” Diabetes 45, no. 4 (April 1996): 434–39. https://doi.org/10.2337/diab.45.4.434.
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    • Ulshen, M. H., E. C. Hoyt, C. R. Fuller, M. A. Ghatei, S. R. Bloom, and P. K. Lund. “Increased ileal proglucagon expression after jejunectomy is not suppressed by inhibition of bowel growth..” Dig Dis Sci 41, no. 4 (April 1996): 677–83. https://doi.org/10.1007/bf02213122.
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    • Murray, S. C., R. S. Sandler, T. O. Keku, C. M. Lyles, R. C. Millikan, S. I. Bangdiwala, L. L. Kupper, W. Jiang, and M. H. Ulshen. “Comparison of rectal mucosal proliferation measured by proliferating cell nuclear antigen (PCNA) immunohistochemistry and whole crypt dissection..” Cancer Epidemiol Biomarkers Prev 4, no. 7 (October 1995): 715–20.
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    • Rhoads, J. M., M. H. Ulshen, E. O. Keku, W. Chen, H. M. Kandil, J. P. Woodard, S. C. Liu, C. R. Fuller, H. L. Leary, and J. G. Lecce. “Oral transforming growth factor-alpha enhances jejunal mucosal recovery and electrical resistance in piglet rotavirus enteritis..” Pediatr Res 38, no. 2 (August 1995): 173–81. https://doi.org/10.1203/00006450-199508000-00007.
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    • Winesett, D. E., M. H. Ulshen, E. C. Hoyt, N. K. Mohapatra, C. R. Fuller, and P. K. Lund. “Regulation and localization of the insulin-like growth factor system in small bowel during altered nutrient status..” Am J Physiol 268, no. 4 Pt 1 (April 1995): G631–40. https://doi.org/10.1152/ajpgi.1995.268.4.G631.
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    • Winesett, D. E., M. H. Ulshen, E. C. Hoyt, N. K. Mohapatra, C. R. Fuller, and P. K. Lund. “Regulation and localization of the insulin-like growth factor system in small bowel during altered nutrient status.” American Journal of Physiology  Gastrointestinal and Liver Physiology 268, no. 4 31-4 (January 1, 1995).
    • Lyles, C. M., R. S. Sandler, T. O. Keku, L. L. Kupper, R. C. Millikan, S. C. Murray, S. I. Bangdiwala, and M. H. Ulshen. “Reproducibility and variability of the rectal mucosal proliferation index using proliferating cell nuclear antigen immunohistochemistry..” Cancer Epidemiol Biomarkers Prev 3, no. 7 (October 1994): 597–605.
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    • Garfunkel, J. M., M. H. Ulshen, H. J. Hamrick, and E. E. Lawson. “Effect of institutional prestige on reviewers' recommendations and editorial decisions..” Jama 272, no. 2 (July 13, 1994): 137–38.
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    • Ferry, G. D., B. S. Kirschner, R. J. Grand, R. M. Issenman, A. M. Griffiths, J. A. Vanderhoof, S. C. Fiedorek, H. S. Winter, E. G. Hassall, and J. B. Watkins. “Olsalazine versus sulfasalazine in mild to moderate childhood ulcerative colitis: results of the Pediatric Gastroenterology Collaborative Research Group Clinical Trial..” J Pediatr Gastroenterol Nutr 17, no. 1 (July 1993): 32–38. https://doi.org/10.1097/00005176-199307000-00005.
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    • Ulshen, M. H., R. H. Dowling, C. R. Fuller, E. M. Zimmermann, and P. K. Lund. “Enhanced growth of small bowel in transgenic mice overexpressing bovine growth hormone..” Gastroenterology 104, no. 4 (April 1993): 973–80. https://doi.org/10.1016/0016-5085(93)90263-c.
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    • Lund, P. K., E. Hoyt, J. G. Simmons, and M. H. Ulshen. “Regulation of intestinal glucagon gene expression during adaptive growth of small intestine.” Digestion 54, no. 6 (January 1, 1993): 371–73. https://doi.org/10.1159/000201058.
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    • Markowitz, J., K. Grancher, F. Mandel, and F. Daum. “Immunosuppressive therapy in pediatric inflammatory bowel disease: results of a survey of the North American Society for Pediatric Gastroenterology and Nutrition. Subcommittee on Immunosuppressive Use of the Pediatric IBD Collaborative Research Forum..” Am J Gastroenterol 88, no. 1 (January 1993): 44–48.
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    • Sandler, R. S., M. H. Ulshen, C. M. Lyles, C. A. McAuliffe, and C. R. Fuller. “Rectal mucosal ornithine decarboxylase activity is not a useful marker of risk for colorectal neoplasia..” Dig Dis Sci 37, no. 11 (November 1992): 1718–24. https://doi.org/10.1007/bf01299865.
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    • Rountree, D. B., M. H. Ulshen, S. Selub, C. R. Fuller, S. R. Bloom, M. A. Ghatei, and P. K. Lund. “Nutrient-independent increases in proglucagon and ornithine decarboxylase messenger RNAs after jejunoileal resection..” Gastroenterology 103, no. 2 (August 1992): 462–68. https://doi.org/10.1016/0016-5085(92)90835-m.
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    • Ulshen, M. H., J. G. Lecce, A. D. Stiles, and L. E. Lyn-Cook. “Effects of nursing on growth and development of small bowel mucosa in newborn piglets..” Pediatr Res 30, no. 4 (October 1991): 337–41. https://doi.org/10.1203/00006450-199110000-00009.
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    • Markowitz, J., F. Daum, S. A. Cohen, M. Glassman, R. D. Holmes, D. Piccoli, T. M. Rossi, W. R. Treem, M. H. Ulshen, and H. S. Winter. “Immunology of inflammatory bowel disease: summary of the proceedings of the Subcommittee on Immunosuppressive Use in IBD..” J Pediatr Gastroenterol Nutr 12, no. 4 (May 1991): 411–23.
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    • Ulshen, M. H. “Routine laparoscopy in the management of chronic hepatitis..” J Pediatr 117, no. 3 (September 1990): 417–18. https://doi.org/10.1016/s0022-3476(05)81082-0.
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    • Garfunkel, J. M., E. E. Lawson, H. J. Hamrick, and M. H. Ulshen. “Effect of acceptance or rejection on the author's evaluation of peer review of medical manuscripts..” Jama 263, no. 10 (March 9, 1990): 1376–78.
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    • Garfunkel, J. M., M. H. Ulshen, H. J. Hamrick, and E. E. Lawson. “Problems identified by secondary review of accepted manuscripts..” Jama 263, no. 10 (March 9, 1990): 1369–71.
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    • Lund, P. K., M. H. Ulshen, D. B. Rountree, S. E. Selub, and A. M. Buchan. “Molecular biology of gastrointestinal peptides and growth factors: relevance to intestinal adaptation..” Digestion 46 Suppl 2 (1990): 66–73. https://doi.org/10.1159/000200369.
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    • Ulshen, M. H., and J. M. Garfunkel. “The editorial process of evaluation and selection of manuscripts: Experience at the Journal of Pediatrics.” Serials Review 16, no. 2 (January 1, 1990): 29–31. https://doi.org/10.1016/0098-7913(90)90003-H.
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    • Kleinman, R. E., N. F. Galeano, F. Ghishan, E. Lebenthal, J. Sutphen, and M. H. Ulshen. “Nutritional management of chronic diarrhea and/or malabsorption..” J Pediatr Gastroenterol Nutr 9, no. 4 (November 1989): 407–15. https://doi.org/10.1097/00005176-198911000-00002.
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    • Ulshen, M. “α₁-Antitrypsin deficiency: Two wrongs can make a right.” Gastroenterology 97, no. 1 (1989): 225–26.
    • Ulshen, M. “Unraveling sucrase-isomaltase "deficiency" states.” Gastroenterology 96, no. 1 (1989): 259–60.
    • Bishop, W. P., and M. H. Ulshen. “Bacterial gastroenteritis..” Pediatr Clin North Am 35, no. 1 (February 1988): 69–87. https://doi.org/10.1016/s0031-3955(16)36400-8.
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    • Ulshen, M. H. “Refeeding during recovery from acute diarrhea..” J Pediatr 112, no. 2 (February 1988): 239–40. https://doi.org/10.1016/s0022-3476(88)80061-1.
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    • Ulshen, M. H. “Gastroesophageal reflux in infancy.” Gastroenterology 95, no. 2 (January 1, 1988): 534–35. https://doi.org/10.1016/0016-5085(88)90517-3.
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    • Ulshen, M. H. “Treatment of gastroesophageal reflux: is nothing sacred?.” J Pediatr 110, no. 2 (February 1987): 254–55. https://doi.org/10.1016/s0022-3476(87)80165-8.
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    • Groben, P. A., G. P. Siegal, M. D. Shub, M. H. Ulshen, and F. B. Askin. “Gastroesophageal reflux and esophagitis in infants and children..” Perspect Pediatr Pathol 11 (1987): 124–51.
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    • Ulshen, M. H. “Natural history of Cryptosporidia.” Gastroenterology 93, no. 1 (January 1, 1987): 205–6. https://doi.org/10.1016/0016-5085(87)90338-6.
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    • Ulshen, M. H. “Liver transplantation in the infant.” Gastroenterology 93, no. 5 (January 1, 1987): 1139–40. https://doi.org/10.1016/0016-5085(87)90586-5.
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    • Ulshen, M. H. “To dry or not to dry, that is the question.” Gastroenterology 92, no. 2 (January 1, 1987): 542–43. https://doi.org/10.1016/0016-5085(87)90159-4.
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    • Ulshen, M. H., L. E. Lyn-Cook, and R. H. Raasch. “Effects of intraluminal epidermal growth factor on mucosal proliferation in the small intestine of adult rats..” Gastroenterology 91, no. 5 (November 1986): 1134–40. https://doi.org/10.1016/s0016-5085(86)80008-7.
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    • Tobey, N. A., L. E. Lyn-Cook, M. H. Ulshen, and W. D. Heizer. “Intestinal brush border peptidases: activities in normal and abnormal peroral intestinal biopsy specimens..” J Lab Clin Med 107, no. 3 (March 1986): 221–27.
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    • Ulshen, M. H. “Salicylates and Reye's syndrome.” Gastroenterology 91, no. 2 (January 1, 1986): 487–88. https://doi.org/10.1016/0016-5085(86)90594-9.
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    • Ulshen, M. H. “To treat or not to treat.” Gastroenterology 91, no. 6 (January 1, 1986): 1569–70. https://doi.org/10.1016/0016-5085(86)90218-0.
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    • Ulshen, M. H. “A promising rotavirus vaccine.” Gastroenterology 90, no. 1 (January 1, 1986): 246–47. https://doi.org/10.1016/0016-5085(86)90105-8.
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    • Shub, M. D., M. H. Ulshen, C. B. Hargrove, G. P. Siegal, P. A. Groben, and F. B. Askin. “Esophagitis: a frequent consequence of gastroesophageal reflux in infancy..” J Pediatr 107, no. 6 (December 1985): 881–84. https://doi.org/10.1016/s0022-3476(85)80180-3.
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    • Ulshen, M. H., and C. A. Herbst. “Effect of proximal transposition of the ileum on mucosal growth and enzyme activity in orally nourished rats..” Am J Clin Nutr 42, no. 5 (November 1985): 805–14. https://doi.org/10.1093/ajcn/42.5.805.
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    • Ulshen, M. H. “Guilt not by association.” Gastroenterology 89, no. 6 (January 1, 1985): 1436–37. https://doi.org/10.1016/0016-5085(85)90668-7.
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    • Ulshen, M. H. “Drink your milk!.” Gastroenterology 89, no. 3 (January 1, 1985): 695–96. https://doi.org/10.1016/0016-5085(85)90476-7.
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    • Ulshen, M. H. “Screening for celiac disease: Are we there yet?.” Gastroenterology 89, no. 1 (January 1, 1985): 217–18. https://doi.org/10.1016/0016-5085(85)90767-X.
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    • Ulshen, M. H. “Is polyamine biosynthesis necessary for intestinal adaptation?.” Gastroenterology 88, no. 6 (January 1, 1985): 2006–7. https://doi.org/10.1016/0016-5085(85)90036-8.
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    • Ulshen, M. H. “Vitamin E in cholestasis.” Gastroenterology 88, no. 2 (January 1, 1985): 588–89. https://doi.org/10.1016/0016-5085(85)90526-8.
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    • Hargrove, C. B., M. H. Ulshen, and M. D. Shub. “Upper gastrointestinal endoscopy in infants: diagnostic usefulness and safety..” Pediatrics 74, no. 5 (November 1984): 828–31.
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    • Powell, T. W., C. A. Herbst, and M. Ulshen. “Mallory-Weiss syndrome in a 10-month-old infant requiring surgery..” J Pediatr Surg 19, no. 5 (October 1984): 596–97. https://doi.org/10.1016/s0022-3468(84)80113-x.
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    • Long, W. A., M. H. Ulshen, and E. E. Lawson. “Clinical manifestations of congenital syphilitic hepatitis: implications for pathogenesis..” J Pediatr Gastroenterol Nutr 3, no. 4 (September 1984): 551–55. https://doi.org/10.1097/00005176-198409000-00013.
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    • Ulshen, M. H. “Would you believe the tongue?.” Gastroenterology 87, no. 3 (September 1, 1984): 732–33.
    • Ulshen, M. H. “To shunt or not to shunt?.” Gastroenterology 87, no. 2 (August 1, 1984): 446–47.
    • Stafford, S. J., M. H. Ulshen, and J. Mandell. “Familial visceral myopathy..” J Urol 131, no. 5 (May 1984): 978–80. https://doi.org/10.1016/s0022-5347(17)50737-5.
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    • Ulshen, M. H., and C. A. Herbst. “Effect of removal of pancreaticobiliary secretions on adaptation to short bowel in orally nourished rats..” Am J Clin Nutr 39, no. 5 (May 1984): 762–70. https://doi.org/10.1093/ajcn/39.5.762.
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    • Schwarz, R. P., and M. H. Ulshen. “Pseudomembranous colitis presenting as mild, chronic diarrhea in childhood..” J Pediatr Gastroenterol Nutr 2, no. 3 (1983): 570–73. https://doi.org/10.1097/00005176-198302030-00030.
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    • Devore, C. D., M. H. Ulshen, and R. E. Cross. “Phenolphthalein laxatives and factitious diarrhea..” Clin Pediatr (Phila) 21, no. 9 (September 1982): 573–74. https://doi.org/10.1177/000992288202100911.
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    • Everett, C., F. Volberg, M. Ulshen, and G. Murray. “Intramural esophageal hamartoma: a report of two cases and review of the literature..” Gastrointest Radiol 5, no. 4 (November 15, 1980): 317–19.
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    • Ulshen, M. H., and J. L. Rollo. “Pathogenesis of escherichia coli gastroenteritis in man--another mechanism..” N Engl J Med 302, no. 2 (January 10, 1980): 99–101. https://doi.org/10.1056/NEJM198001103020207.
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    • Ulshen, M. H., and R. J. Grand. “Site of substrate stimulation of jejunal sucrase in the rat..” J Clin Invest 64, no. 4 (October 1979): 1097–1102. https://doi.org/10.1172/JCI109548.
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    • Ulshen, M. H., R. J. Grand, J. D. Crain, and E. W. Gelfand. “Hepatoxicity with encephalopathy associated with aspirin therapy in rheumatoid arthritis..” J Pediatr 93, no. 6 (December 1978): 1034–37. https://doi.org/10.1016/s0022-3476(78)81252-9.
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    • Ulshen, M. H., and R. J. Grand. “Effects of cholestyramine on small intestinal mucosa.” Pediatric Research 12, no. 4 II (January 1, 1978).
    • Grand, R. J., and M. H. Ulshen. “Clinical and physiological abnormalities in hepatic function..” Pediatr Clin North Am 22, no. 4 (November 1975): 897–928. https://doi.org/10.1016/s0031-3955(16)33215-1.
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