Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Fellow in Infectious Diseases, Medicine, Duke University 1983 - 1985
  • Resident, Medicine, Duke University 1980 - 1983
  • M.D., Duke University 1980
• 

  Duke Appointment History

  • Chair, Department of Medicine, Medicine, Clinical Science Departments 2010 - 2017
  • Consulting Associate in the Department of Medicine, Medicine, Infectious Diseases, Medicine 2010
  • Assistant Professor, Medicine, Clinical Science Departments 1986 - 1990
  • Associate, Medicine, Clinical Science Departments 1985 - 1986
• Recognition
• 

  In the News

  • MAY 18, 2018

    Viewpoints podcast

    What's Duke Doing to Better Understand and Treat Brain Diseases?

  • MAR 5, 2018

    Viewpoints podcast

    Why is it Important to Explore the Early-life Origins of Health and Disease?

  • JAN 19, 2018

    Viewpoint podcast

    Dean Mary Klotman on Translating Duke Health

  • NOV 2, 2017

    School of Medicine Viewpoint Podcast

    Mary Klotman: What Did it Take to Change HIV From a Fatal Diagnosis to an Often-manageable, Disease?

  • OCT 10, 2017

    School of Medicine Viewpoint

    Mary Klotman: What is Data Science and Why Is It Important?

  • AUG 29, 2017

    Dr. Mary Klotman: Why Diversity Is Necessary in Academic Medicine

  • JUL 11, 2017

    From Undergraduate to Dean: Dr. Mary Klotman Describes What She Has Learned at Duke

  • MAY 25, 2017

    School of Medicine

    Duke Hosts Precision Medicine World Conference

  • APR 24, 2017

    Duke School of Medicine

    Klotman Joins Roundtable Discussion with Rep. David Price to Discuss NIH Budget

  • JAN 30, 2017

    Dr. Mary Klotman Named Dean of Duke School of Medicine

  • APR 6, 2015

    The News & Observer

    Duke HIV researchers receive large federal grants

  • APR 5, 2015

    Duke Research Teams Win Large Federal Grants for HIV Vaccine Studies

  • OCT 21, 2014

    Klotman, chair of Medicine, Named to Institute of Medicine
• 

  Awards & Honors

  • Member. Institute of Medicine of The National Academies. 2014
  • Membership. National Academy of Medicine. 2014
• Expertise
• 

  Subject Headings

  • Acquired Immunodeficiency Syndrome
  • Antibodies, Viral
  • Antiretroviral Therapy, Highly Active
  • Drug Carriers
  • Education, Medical
  • Enzyme-Linked Immunospot Assay
  • HIV
  • HIV Infections
  • Health
  • Integrase Inhibitors
  • Kidney
  • Leadership
  • Science
  • Vaccines, Synthetic
• Research
• 

  Selected Grants

  • Medical Scientist Training Program awarded by National Institutes of Health 1997 - 2022
  • Mentoring Patient Oriented Research in Antibiotic-Resistant Bacteria awarded by National Institutes of Health 2011 - 2021
  • Interdisciplinary Research Training Program in AIDS awarded by National Institutes of Health 2010 - 2020
  • The Genitourinary Tract as a compartment and reservoir for HIV awarded by National Institutes of Health 2015 - 2020
  • Integrase Defective Lentiviral Vector (IDLV) for HIV Vaccine Development awarded by National Institutes of Health 2015 - 2020
  • Viral Oncology Training Grant awarded by National Institutes of Health 1980 - 2019
  • Persistent HIV Infection in the Kidney awarded by Baylor College of Medicine 1999 - 2019
  • Systems Biology Approaches for Predicting Cardiometabolic Risk in Persons Living with HIV awarded by National Institutes of Health 2015 - 2018
  • Serial Block Face Scanning Electron Microscope awarded by National Institutes of Health 2016 - 2018
  • Impact of polyploidy on establishing an HIV-1 reservoir in the kidney awarded by University of Alabama at Birmingham 2014 - 2017
  • The Pathogenesis of HIV-Associated Nephropathy awarded by Baylor College of Medicine 2011 - 2016
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Negri, D, Blasi, M, LaBranche, C, Parks, R, Balachandran, H, Lifton, M, Shen, X, Denny, T, Ferrari, G, Vescio, MF, Andersen, H, Montefiori, DC, Tomaras, GD, Liao, H-X, Santra, S, Haynes, BF, Klotman, ME, and Cara, A. "Immunization with an SIV-based IDLV Expressing HIV-1 Env 1086 Clade C Elicits Durable Humoral and Cellular Responses in Rhesus Macaques." Molecular Therapy : the Journal of the American Society of Gene Therapy 24, no. 11 (November 2016): 2021-2032.  Full Text  Open Access Copy
    • Chen, P, Yi, Z, Zhang, W, Klotman, ME, and Chen, BK. "HIV infection-induced transcriptional program in renal tubular epithelial cells activates a CXCR2-driven CD4+ T-cell chemotactic response." Aids (London, England) 30, no. 12 (July 2016): 1877-1888.  Full Text
    • Blasi, M, Carpenter, JH, Balakumaran, B, Cara, A, Gao, F, and Klotman, ME. "Identification of HIV-1 genitourinary tract compartmentalization by analyzing the env gene sequences in urine." Aids (London, England) 29, no. 13 (August 2015): 1651-1657.  Full Text
    • Michelini, Z, Negri, D, Biava, M, Baroncelli, S, Spada, M, Leone, P, Bona, R, Blasi, M, Nègre, D, Klotman, ME, and Cara, A. "Murine granulocyte-macrophage colony-stimulating factor expressed from a bicistronic simian immunodeficiency virus-based integrase-defective lentiviral vector does not enhance T-cell responses in mice." Viral Immunology 27, no. 10 (December 2014): 512-520.  Full Text
    • Carethers, JM, Coughlin, S, Diamond, B, Erzurum, S, Fried, LP, Jameson, JL, Kaushansky, K, Klotman, ME, Lemon, S, Mitchell, B, Rothman, P, Sawyers, C, Seidman, C, and Somlo, S. "The imperative to invest in science has never been greater." The Journal of Clinical Investigation 124, no. 11 (November 2014): 5085-null.  Full Text
    • Blasi, M, Balakumaran, B, Chen, P, Negri, DRM, Cara, A, Chen, BK, and Klotman, ME. "Renal epithelial cells produce and spread HIV-1 via T-cell contact." Aids (London, England) 28, no. 16 (October 2014): 2345-2353.  Full Text
    • Carethers, JM, Coughlin, S, Diamond, B, Erzurum, S, Fried, LP, Jameson, JL, Kaushansky, K, Klotman, ME, Lemon, S, Mitchell, B, Rothman, P, Sawyers, C, Seidman, C, and Somlo, S. "The imperative to invest in science has never been greater." The Journal of Clinical Investigation 124, no. 9 (September 2, 2014): 3680-3681.  Full Text
    • Blasi, M, Balakumaran, B, Chen, P, Negri, DRM, Cara, A, Chen, BK, and Klotman, ME. "Renal epithelial cells produce and spread HIV-1 via T-cell contact." Aids 28, no. 16 (January 1, 2014): 2345-2353.  Full Text
    • Rossi, A, Michelini, Z, Leone, P, Borghi, M, Blasi, M, Bona, R, Spada, M, Grasso, F, Gugliotta, A, Klotman, ME, Cara, A, and Negri, D. "Optimization of mucosal responses after intramuscular immunization with integrase defective lentiviral vector." Plos One 9, no. 9 (January 2014): e107377-null.  Full Text
    • Micsenyi, AM, Zony, C, Alvarez, RA, Durham, ND, Chen, BK, and Klotman, ME. "Postintegration HIV-1 infection of cervical epithelial cells mediates contact-dependent productive infection of T cells." The Journal of Infectious Diseases 208, no. 11 (December 2013): 1756-1767.  Full Text
    • Hutter, R, Huang, L, Speidl, WS, Giannarelli, C, Trubin, P, Bauriedel, G, Klotman, ME, Fuster, V, Badimon, JJ, and Klotman, PE. "Novel small leucine-rich repeat protein podocan is a negative regulator of migration and proliferation of smooth muscle cells, modulates neointima formation, and is expressed in human atheroma." Circulation 128, no. 22 (November 26, 2013): 2351-2363.  Full Text
    • Hutter, R, Huang, L, Speidl, WS, Giannarelli, C, Trubin, P, Bauriedel, G, Klotman, ME, Fuster, V, Badimon, JJ, and Klotman, PE. "Novel small leucine-rich repeat protein podocan is a negative regulator of migration and proliferation of smooth muscle cells, modulates neointima formation, and is expressed in human atheroma." Circulation 128, no. 22 (November 2013): 2351-2363.  Full Text
    • Todd, RF, Salata, RA, Klotman, ME, Weisfeldt, ML, Katz, JT, Xian, SX, Hearn, DP, and Lipner, RS. "Career outcomes of the graduates of the American Board of Internal Medicine Research Pathway, 1995-2007." Academic Medicine : Journal of the Association of American Medical Colleges 88, no. 11 (November 2013): 1747-1753.  Full Text
    • Todd, RF, Salata, RA, Klotman, ME, Weisfeldt, ML, Katz, JT, Xian, SX, Hearn, DP, and Lipner, RS. "Career outcomes of the graduates of the American board of internal medicine research pathway, 1995-2007." Academic Medicine 88, no. 11 (January 1, 2013): 1747-1753.  Full Text
    • Blasi, M, Rossi, A, Michelini, Z, Leone, P, Perretta, G, Cimarelli, A, Klotman, M, Negri, D, and Cara, A. "Simian immunodeficiency virus-Vpx as an adjuvant for integrase defective lentiviral vector-based vaccines." Retrovirology 9, no. Suppl 2 (2012): P293-P293.  Full Text
    • Negri, DRM, Rossi, A, Blasi, M, Michelini, Z, Leone, P, Chiantore, MV, Baroncelli, S, Perretta, G, Cimarelli, A, Klotman, ME, and Cara, A. "Simian immunodeficiency virus-Vpx for improving integrase defective lentiviral vector-based vaccines." Retrovirology 9 (January 2012): 69-null.  Full Text
    • Papeta, N, Kiryluk, K, Patel, A, Sterken, R, Kacak, N, Snyder, HJ, Imus, PH, Mhatre, AN, Lawani, AK, Julian, BA, Wyatt, RJ, Novak, J, Wyatt, CM, Ross, MJ, Winston, JA, Klotman, ME, Cohen, DJ, Appel, GB, D'Agati, VD, Klotman, PE, and Gharavi, AG. "APOL1 variants increase risk for FSGS and HIVAN but not IgA nephropathy." Journal of the American Society of Nephrology : Jasn 22, no. 11 (November 2011): 1991-1996.  Full Text
    • Jao, J, Palmer, D, Leus, I, Tih, P, Baweja, M, Klotman, M, Sperling, R, and Wyatt, C. "Prevalence and predictors of proteinuria in HIV-infected and uninfected pregnant women in Cameroon." Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association European Renal Association 26, no. 9 (September 2011): 3051-3053.  Full Text
    • Chen, P, Chen, BK, Mosoian, A, Hays, T, Ross, MJ, Klotman, PE, and Klotman, ME. "Virological synapses allow HIV-1 uptake and gene expression in renal tubular epithelial cells." Journal of the American Society of Nephrology : Jasn 22, no. 3 (March 2011): 496-507.  Full Text
    • Ding, J, Rapista, A, Teleshova, N, Lu, W, Klotman, ME, and Chang, TL. "Mucosal human defensins 5 and 6 antagonize the anti-HIV activity of candidate polyanion microbicides." Journal of Innate Immunity 3, no. 2 (January 2011): 208-212.  Full Text
    • Chang, TL, and Klotman, M. "Defensins and HIV infection." (December 1, 2010): 51-63. (Chapter)  Full Text
    • Negri, DRM, Bona, R, Michelini, Z, Leone, P, Macchia, I, Klotman, ME, Salvatore, M, and Cara, A. "Transduction of human antigen-presenting cells with integrase-defective lentiviral vector enables functional expansion of primed antigen-specific CD8(+) T cells." Human Gene Therapy 21, no. 8 (August 2010): 1029-1035.  Full Text
    • Tuyama, AC, Hong, F, Saiman, Y, Wang, C, Ozkok, D, Mosoian, A, Chen, P, Chen, BK, Klotman, ME, and Bansal, MB. "Human immunodeficiency virus (HIV)-1 infects human hepatic stellate cells and promotes collagen I and monocyte chemoattractant protein-1 expression: implications for the pathogenesis of HIV/hepatitis C virus-induced liver fibrosis." Hepatology (Baltimore, Md.) 52, no. 2 (August 2010): 612-622.  Full Text
    • Mosoian, A, Teixeira, A, Burns, CS, Sander, LE, Gusella, GL, He, C, Blander, JM, Klotman, P, and Klotman, ME. "Prothymosin-alpha inhibits HIV-1 via Toll-like receptor 4-mediated type I interferon induction." Proceedings of the National Academy of Sciences of the United States of America 107, no. 22 (June 2010): 10178-10183.  Full Text
    • Snyder, A, Alsauskas, ZC, Leventhal, JS, Rosenstiel, PE, Gong, P, Chan, JJK, Barley, K, He, JC, Klotman, ME, Ross, MJ, and Klotman, PE. "HIV-1 viral protein r induces ERK and caspase-8-dependent apoptosis in renal tubular epithelial cells." Aids (London, England) 24, no. 8 (May 2010): 1107-1119.  Full Text
    • Ding, J, Rapista, A, Teleshova, N, Mosoyan, G, Jarvis, GA, Klotman, ME, and Chang, TL. "Neisseria gonorrhoeae enhances HIV-1 infection of primary resting CD4+ T cells through TLR2 activation." Journal of Immunology (Baltimore, Md. : 1950) 184, no. 6 (March 2010): 2814-2824.  Full Text
    • Negri, DRM, Michelini, Z, Baroncelli, S, Spada, M, Vendetti, S, Bona, R, Leone, P, Klotman, ME, and Cara, A. "Nonintegrating Lentiviral Vector-Based Vaccine Efficiently Induces Functional and Persistent CD8+ T Cell Responses in Mice." Journal of Biomedicine & Biotechnology 2010 (January 2010): 534501-null.  Full Text
    • Snyder, A, Alsauskas, Z, Gong, P, Rosenstiel, PE, Klotman, ME, Klotman, PE, and Ross, MJ. "FAT10: a novel mediator of Vpr-induced apoptosis in human immunodeficiency virus-associated nephropathy." Journal of Virology 83, no. 22 (November 2009): 11983-11988.  Full Text
    • Factor, SH, and Klotman, ME. "Zoonotic infections: an emerging threat to human health." The Mount Sinai Journal of Medicine, New York 76, no. 5 (October 2009): 419-420.  Full Text
    • Feng, X, Lu, T-C, Chuang, PY, Fang, W, Ratnam, K, Xiong, H, Ouyang, X, Shen, Y, Levy, DE, Hyink, D, Klotman, M, D'Agati, V, Iyengar, R, Klotman, PE, and He, JC. "Reduction of Stat3 activity attenuates HIV-induced kidney injury." Journal of the American Society of Nephrology : Jasn 20, no. 10 (October 2009): 2138-2146.  Full Text
    • Chen, W-H, Janout, V, Kondo, M, Mosoian, A, Mosoyan, G, Petrov, RR, Klotman, ME, and Regen, SL. "A fine line between molecular umbrella transport and ionophoric activity." Bioconjugate Chemistry 20, no. 9 (September 2009): 1711-1715.  Full Text
    • Rosenstiel, PE, Chan, J, Snyder, A, Planelles, V, D'Agati, VD, Klotman, PE, and Klotman, ME. "HIV-1 Vpr activates the DNA damage response in renal tubule epithelial cells." Aids (London, England) 23, no. 15 (September 2009): 2054-2056.  Full Text
    • Michelini, Z, Negri, DRM, Baroncelli, S, Spada, M, Leone, P, Bona, R, Klotman, ME, and Cara, A. "Development and use of SIV-based Integrase defective lentiviral vector for immunization." Vaccine 27, no. 34 (July 2009): 4622-4629.  Full Text
    • Sachdev, DD, Zerhouni-Layachi, B, Ortigoza, M, Profy, AT, Tuen, M, Hioe, CE, and Klotman, ME. "The differential binding and activity of PRO 2000 against diverse HIV-1 envelopes." Journal of Acquired Immune Deficiency Syndromes (1999) 51, no. 2 (June 2009): 125-129.  Full Text
    • Wyatt, CM, Morgello, S, Katz-Malamed, R, Wei, C, Klotman, ME, Klotman, PE, and D'Agati, VD. "The spectrum of kidney disease in patients with AIDS in the era of antiretroviral therapy." Kidney International 75, no. 4 (February 2009): 428-434.  Full Text
    • Abbadessa, G, Accolla, R, Aiuti, F, Albini, A, Aldovini, A, Alfano, M, Antonelli, G, Bartholomew, C, Bentwich, Z, Bertazzoni, U, Berzofsky, JA, Biberfeld, P, Boeri, E, Buonaguro, L, Buonaguro, FM, Bukrinsky, M, Burny, A, Caruso, A, Cassol, S, Chandra, P, Ceccherini-Nelli, L, Chieco-Bianchi, L, Clerici, M, Colombini-Hatch, S, de Giuli Morghen, C, de Maria, A, de Rossi, A, Dierich, M, Della-Favera, R, Dolei, A, Douek, D, Erfle, V, Felber, B, Fiorentini, S, Franchini, G, Gershoni, JM, Gotch, F, Green, P, Greene, WC, Hall, W, Haseltine, W, Jacobson, S, Kallings, LO, Kalyanaraman, VS, Katinger, H, Khalili, K, Klein, G, Klein, E, Klotman, M, Klotman, P, Kotler, M, Kurth, R, Lafeuillade, A, La Placa, M, Lewis, J, Lillo, F, Lisziewicz, J, Lomonico, A, Lopalco, L, Lori, F, Lusso, P, Macchi, B, Malim, M, Margolis, L, Markham, PD, McClure, M, Miller, N, Mingari, MC, Moretta, L, Noonan, D, O'Brien, S, Okamoto, T, Pal, R, Palese, P, Panet, A, Pantaleo, G, Pavlakis, G, Pistello, M, Plotkin, S, Poli, G, Pomerantz, R, Radaelli, A, Robertguroff, M, Roederer, M, Sarngadharan, MG, Schols, D, Secchiero, P, Shearer, G, Siccardi, A, Stevenson, M, Svoboda, J, Tartaglia, J, Torelli, G, Tornesello, ML, Tschachler, E, Vaccarezza, M, Vallbracht, A, van Lunzen, J, Varnier, O, Vicenzi, E, von Melchner, H, Witz, I, Zagury, D, Zagury, J-F, Zauli, G, and Zipeto, D. "Unsung hero Robert C. Gallo." Science (New York, N.Y.) 323, no. 5911 (January 2009): 206-207. (Letter)  Full Text
    • Radbill, BD, Wyatt, CM, Vassalotti, JA, Klotman, ME, and Klotman, PE. "Hepatitis B- and HIV-Related Renal Diseases." (December 1, 2008): 272-280. (Chapter)  Full Text
    • Vargas, J, Klotman, ME, and Cara, A. "Conditionally replicating lentiviral-hybrid episomal vectors for suicide gene therapy." Antiviral Research 80, no. 3 (December 2008): 288-294.  Full Text
    • Rosenstiel, PE, Gruosso, T, Letourneau, AM, Chan, JJ, LeBlanc, A, Husain, M, Najfeld, V, Planelles, V, D'Agati, VD, Klotman, ME, and Klotman, PE. "HIV-1 Vpr inhibits cytokinesis in human proximal tubule cells." Kidney International 74, no. 8 (October 2008): 1049-1058.  Full Text
    • Klotman, ME, Rapista, A, Teleshova, N, Micsenyi, A, Jarvis, GA, Lu, W, Porter, E, and Chang, TL. "Neisseria gonorrhoeae-induced human defensins 5 and 6 increase HIV infectivity: role in enhanced transmission." Journal of Immunology (Baltimore, Md. : 1950) 180, no. 9 (May 2008): 6176-6185.  Full Text
    • Teleshova, N, Chang, T, Profy, A, and Klotman, ME. "Inhibitory effect of PRO 2000, a candidate microbicide, on dendritic cell-mediated human immunodeficiency virus transfer." Antimicrobial Agents and Chemotherapy 52, no. 5 (May 2008): 1751-1758.  Full Text
    • Eugenin, EA, Morgello, S, Klotman, ME, Mosoian, A, Lento, PA, Berman, JW, and Schecter, AD. "Human immunodeficiency virus (HIV) infects human arterial smooth muscle cells in vivo and in vitro: implications for the pathogenesis of HIV-mediated vascular disease." The American Journal of Pathology 172, no. 4 (April 2008): 1100-1111.  Full Text
    • Chang, TL, Teleshova, N, Rapista, A, Paluch, M, Anderson, RA, Waller, DP, Zaneveld, LJD, Granelli-Piperno, A, and Klotman, ME. "SAMMA, a mandelic acid condensation polymer, inhibits dendritic cell-mediated HIV transmission." Febs Letters 581, no. 24 (October 2007): 4596-4602.  Full Text
    • Wyatt, CM, Winston, JA, Malvestutto, CD, Fishbein, DA, Barash, I, Cohen, AJ, Klotman, ME, and Klotman, PE. "Chronic kidney disease in HIV infection: an urban epidemic." Aids (London, England) 21, no. 15 (October 2007): 2101-2103.  Full Text
    • Mosoian, A, Teixeira, A, Burns, CS, Khitrov, G, Zhang, W, Gusella, L, Klotman, P, and Klotman, M. "Influence of prothymosin-alpha on HIV-1 target cells." Annals of the New York Academy of Sciences 1112 (September 2007): 269-285. (Review)  Full Text
    • Negri, DRM, Michelini, Z, Baroncelli, S, Spada, M, Vendetti, S, Buffa, V, Bona, R, Leone, P, Klotman, ME, and Cara, A. "Successful immunization with a single injection of non-integrating lentiviral vector." Molecular Therapy : the Journal of the American Society of Gene Therapy 15, no. 9 (September 2007): 1716-1723.  Full Text
    • Negri, DRM, Michelini, Z, Baroncelli, S, Spada, M, Vendetti, S, Buffa, V, Bona, R, Leone, P, Klotman, ME, and Cara, A. "Successful immunization with a single injection of non-integrating lentiviral vector." Molecular Therapy 15, no. 9 (September 1, 2007): 1716-1723. (Academic Article)  Full Text  Link to Item
    • Salvatore, M, Garcia-Sastre, A, Ruchala, P, Lehrer, RI, Chang, T, and Klotman, ME. "alpha-Defensin inhibits influenza virus replication by cell-mediated mechanism(s)." The Journal of Infectious Diseases 196, no. 6 (September 2007): 835-843.  Full Text
    • Bhadelia, N, Klotman, M, and Caplivski, D. "The HIV-positive traveler." The American Journal of Medicine 120, no. 7 (July 2007): 574-580. (Review)  Full Text
    • Kaufman, L, Yang, G, Hayashi, K, Ashby, JR, Huang, L, Ross, MJ, Klotman, ME, and Klotman, PE. "The homophilic adhesion molecule sidekick-1 contributes to augmented podocyte aggregation in HIV-associated nephropathy." Faseb Journal : Official Publication of the Federation of American Societies for Experimental Biology 21, no. 7 (May 2007): 1367-1375.  Full Text
    • Cara, A, and Klotman, ME. "Retroviral E-DNA: persistence and gene expression in nondividing immune cells." Journal of Leukocyte Biology 80, no. 5 (November 2006): 1013-1017. (Review)  Full Text
    • Liu, X, Mosoian, A, Li-Yun Chang, T, Zerhouni-Layachi, B, Snyder, A, Jarvis, GA, and Klotman, ME. "Gonococcal lipooligosaccharide suppresses HIV infection in human primary macrophages through induction of innate immunity." The Journal of Infectious Diseases 194, no. 6 (September 2006): 751-759.  Full Text
    • Mosoian, A, Teixeira, A, High, AA, Christian, RE, Hunt, DF, Shabanowitz, J, Liu, X, and Klotman, M. "Novel function of prothymosin alpha as a potent inhibitor of human immunodeficiency virus type 1 gene expression in primary macrophages." Journal of Virology 80, no. 18 (September 2006): 9200-9206.  Full Text
    • Tuyama, ACG, Cheshenko, N, Carlucci, MJ, Li, J-H, Goldberg, CL, Waller, DP, Anderson, RA, Profy, AT, Klotman, ME, Keller, MJ, and Herold, BC. "ACIDFORM inactivates herpes simplex virus and prevents genital herpes in a mouse model: optimal candidate for microbicide combinations." The Journal of Infectious Diseases 194, no. 6 (September 2006): 795-803.  Full Text
    • Klotman, ME, and Chang, TL. "Defensins in innate antiviral immunity." Nature Reviews. Immunology 6, no. 6 (June 2006): 447-456. (Review)  Full Text
    • Ross, MJ, Fan, C, Ross, MD, Chu, T-H, Shi, Y, Kaufman, L, Zhang, W, Klotman, ME, and Klotman, PE. "HIV-1 infection initiates an inflammatory cascade in human renal tubular epithelial cells." Journal of Acquired Immune Deficiency Syndromes (1999) 42, no. 1 (May 2006): 1-11.  Full Text
    • Ross, MJ, Wosnitzer, MS, Ross, MD, Granelli, B, Gusella, GL, Husain, M, Kaufman, L, Vasievich, M, D'Agati, VD, Wilson, PD, Klotman, ME, and Klotman, PE. "Role of ubiquitin-like protein FAT10 in epithelial apoptosis in renal disease." Journal of the American Society of Nephrology : Jasn 17, no. 4 (April 2006): 996-1004.  Full Text
    • Dhawan, D, Keller, M, and Klotman, ME. "Topical microbicides: the time has come." The Aids Reader 16, no. 3 (March 2006): 144-157. (Review)
    • Fierer, DS, and Klotman, ME. "Kidney and central nervous system as reservoirs of HIV infection." Current Opinion in Hiv and Aids 1, no. 2 (March 2006): 115-120.  Full Text
    • Wyatt, CM, Arons, RR, Klotman, PE, and Klotman, ME. "Acute renal failure in hospitalized patients with HIV: risk factors and impact on in-hospital mortality." Aids (London, England) 20, no. 4 (February 2006): 561-565.  Full Text
    • Zerhouni-Layachi, B, Husain, M, Ross, MJ, Marras, D, Sunamoto, M, Liu, X, Klotman, PE, and Klotman, ME. "Dual tropism of HIV-1 envelopes derived from renal tubular epithelial cells of patients with HIV-associated nephropathy." Aids (London, England) 20, no. 4 (February 2006): 621-624.  Full Text
    • Keller, MJ, Zerhouni-Layachi, B, Cheshenko, N, John, M, Hogarty, K, Kasowitz, A, Goldberg, CL, Wallenstein, S, Profy, AT, Klotman, ME, and Herold, BC. "PRO 2000 gel inhibits HIV and herpes simplex virus infection following vaginal application: a double-blind placebo-controlled trial." The Journal of Infectious Diseases 193, no. 1 (January 2006): 27-35.  Full Text
    • Husain, M, D'Agati, VD, He, JC, Klotman, ME, and Klotman, PE. "HIV-1 Nef induces dedifferentiation of podocytes in vivo: a characteristic feature of HIVAN." Aids (London, England) 19, no. 17 (November 2005): 1975-1980.  Full Text
    • John, M, Keller, MJ, Fam, EH, Cheshenko, N, Hogarty, K, Kasowitz, A, Wallenstein, S, Carlucci, MJ, Tuyama, AC, Lu, W, Klotman, ME, Lehrer, RI, and Herold, BC. "Cervicovaginal secretions contribute to innate resistance to herpes simplex virus infection." The Journal of Infectious Diseases 192, no. 10 (November 2005): 1731-1740.  Full Text
    • Scordi-Bello, IA, Mosoian, A, He, C, Chen, Y, Cheng, Y, Jarvis, GA, Keller, MJ, Hogarty, K, Waller, DP, Profy, AT, Herold, BC, and Klotman, ME. "Candidate sulfonated and sulfated topical microbicides: comparison of anti-human immunodeficiency virus activities and mechanisms of action." Antimicrobial Agents and Chemotherapy 49, no. 9 (September 2005): 3607-3615.  Full Text
    • Schwartz, EJ, Szczech, LA, Ross, MJ, Klotman, ME, Winston, JA, and Klotman, PE. "Highly active antiretroviral therapy and the epidemic of HIV+ end-stage renal disease." Journal of the American Society of Nephrology : Jasn 16, no. 8 (August 2005): 2412-2420.  Full Text
    • Chang, TL, Vargas, J, DelPortillo, A, and Klotman, ME. "Dual role of alpha-defensin-1 in anti-HIV-1 innate immunity." The Journal of Clinical Investigation 115, no. 3 (March 2005): 765-773.  Full Text
    • Chang, TL, Vargas, J, DelPortillo, A, and Klotman, ME. "Dual role of alpha-defensin-1 in anti-HIV-1 innate immunity." J Clin Invest 115, no. 3 (March 2005): 765-773.  Full Text  Link to Item
    • Gillim-Ross, L, Cara, A, and Klotman, ME. "Nef expressed from human immunodeficiency virus type 1 extrachromosomal DNA downregulates CD4 on primary CD4+ T lymphocytes: implications for integrase inhibitors." The Journal of General Virology 86, no. Pt 3 (March 2005): 765-771.  Full Text
    • Gillim-Ross, L, Cara, A, and Klotman, ME. "HIV-1 extrachromosomal 2-LTR circular DNA is long-lived in human macrophages." Viral Immunology 18, no. 1 (January 2005): 190-196.  Full Text
    • Jing, B, Janout, V, Herold, BC, Klotman, ME, Heald, T, and Regen, SL. "Persulfated molecular umbrellas as anti-HIV and anti-HSV agents." Journal of the American Chemical Society 126, no. 49 (December 2004): 15930-15931.  Full Text
    • He, JC, Husain, M, Sunamoto, M, D'Agati, VD, Klotman, ME, Iyengar, R, and Klotman, PE. "Nef stimulates proliferation of glomerular podocytes through activation of Src-dependent Stat3 and MAPK1,2 pathways." The Journal of Clinical Investigation 114, no. 5 (September 2004): 643-651.  Full Text
    • He, JC, Husain, M, Sunamoto, M, D'Agati, VD, Klotman, ME, Iyengar, R, and Klotman, PE. "Nef stimulates proliferation of glomerular podocytes through activation of Src-dependent Stat3 and MAPK1,2 pathways." J Clin Invest 114, no. 5 (September 2004): 643-651.  Full Text  Link to Item
    • Chang, TL, and Klotman, ME. "Defensins: natural anti-HIV peptides." Aids Reviews 6, no. 3 (July 2004): 161-168. (Review)
    • Cheshenko, N, Keller, MJ, MasCasullo, V, Jarvis, GA, Cheng, H, John, M, Li, J-H, Hogarty, K, Anderson, RA, Waller, DP, Zaneveld, LJD, Profy, AT, Klotman, ME, and Herold, BC. "Candidate topical microbicides bind herpes simplex virus glycoprotein B and prevent viral entry and cell-to-cell spread." Antimicrobial Agents and Chemotherapy 48, no. 6 (June 2004): 2025-2036.  Full Text
    • Winston, JA, Klotman, PE, and Klotman, M. "Renal Manifestations of HIV Infection." (April 8, 2004): 651-661. (Chapter)  Full Text
    • Vargas, J, Gusella, GL, Najfeld, V, Klotman, ME, and Cara, A. "Novel integrase-defective lentiviral episomal vectors for gene transfer." Human Gene Therapy 15, no. 4 (April 2004): 361-372.  Full Text
    • Ross, MD, Bruggeman, LA, Hanss, B, Sunamoto, M, Marras, D, Klotman, ME, and Klotman, PE. "Podocan, a novel small leucine-rich repeat protein expressed in the sclerotic glomerular lesion of experimental HIV-associated nephropathy." The Journal of Biological Chemistry 278, no. 35 (August 2003): 33248-33255.  Full Text
    • Chang, TL-Y, François, F, Mosoian, A, and Klotman, ME. "CAF-mediated human immunodeficiency virus (HIV) type 1 transcriptional inhibition is distinct from alpha-defensin-1 HIV inhibition." Journal of Virology 77, no. 12 (June 2003): 6777-6784.  Full Text
    • Hernandez, PA, Gorlin, RJ, Lukens, JN, Taniuchi, S, Bohinjec, J, Francois, F, Klotman, ME, and Diaz, GA. "Mutations in the chemokine receptor gene CXCR4 are associated with WHIM syndrome, a combined immunodeficiency disease." Nature Genetics 34, no. 1 (May 2003): 70-74.  Full Text
    • Keller, MJ, Klotman, ME, and Herold, BC. "Rigorous pre-clinical evaluation of topical microbicides to prevent transmission of human immunodeficiency virus." The Journal of Antimicrobial Chemotherapy 51, no. 5 (May 2003): 1099-1102. (Review)  Full Text
    • Keller, MJ, Klotman, ME, and Herold, BC. "Development of topical microbicides for prevention of human immunodeficiency virus and herpes simplex virus." American Journal of Reproductive Immunology (New York, N.Y. : 1989) 49, no. 5 (May 2003): 279-284. (Review)  Full Text
    • François, F, and Klotman, ME. "Phosphatidylinositol 3-kinase regulates human immunodeficiency virus type 1 replication following viral entry in primary CD4+ T lymphocytes and macrophages." Journal of Virology 77, no. 4 (February 2003): 2539-2549.  Full Text
    • Herold, BC, Scordi-Bello, I, Cheshenko, N, Marcellino, D, Dzuzelewski, M, Francois, F, Morin, R, Casullo, VM, Anderson, RA, Chany, C, Waller, DP, Zaneveld, LJD, and Klotman, ME. "Mandelic acid condensation polymer: novel candidate microbicide for prevention of human immunodeficiency virus and herpes simplex virus entry." Journal of Virology 76, no. 22 (November 2002): 11236-11244.  Full Text
    • Husain, M, Gusella, GL, Klotman, ME, Gelman, IH, Ross, MD, Schwartz, EJ, Cara, A, and Klotman, PE. "HIV-1 Nef induces proliferation and anchorage-independent growth in podocytes." Journal of the American Society of Nephrology : Jasn 13, no. 7 (July 2002): 1806-1815.  Full Text
    • Klotman, P, and Klotman, M. "Editorial comment: renal insufficiency in HIV-infected patients may not always be HIVAN." The Aids Reader 12, no. 6 (June 2002): 273-null.
    • Schwartz, EJ, Fierer, DS, Neumann, AU, Keller, MJ, Parkas, V, Zhang, DY, Klotman, ME, Winston, JA, and Klotman, PE. "HIV-1 dynamics in haemodialysis patients." Aids (London, England) 16, no. 9 (June 2002): 1301-1303. (Letter)  Full Text
    • Marras, D, Bruggeman, LA, Gao, F, Tanji, N, Mansukhani, MM, Cara, A, Ross, MD, Gusella, GL, Benson, G, D'Agati, VD, Hahn, BH, Klotman, ME, and Klotman, PE. "Replication and compartmentalization of HIV-1 in kidney epithelium of patients with HIV-associated nephropathy." Nature Medicine 8, no. 5 (May 2002): 522-526.  Full Text
    • Gusella, GL, Fedorova, E, Hanss, B, Marras, D, Klotman, ME, and Klotman, PE. "Lentiviral gene transduction of kidney." Human Gene Therapy 13, no. 3 (February 2002): 407-414.  Full Text
    • Cara, A, Vargas, J, Keller, M, Jones, S, Mosoian, A, Gurtman, A, Cohen, A, Parkas, V, Wallach, F, Chusid, E, Gelman, IH, and Klotman, ME. "Circular viral DNA and anomalous junction sequence in PBMC of HIV-infected individuals with no detectable plasma HIV RNA." Virology 292, no. 1 (January 5, 2002): 1-5.  Full Text  Link to Item
    • Chang, TL-Y, Mosoian, A, Pine, R, Klotman, ME, and Moore, JP. "A soluble factor(s) secreted from CD8(+) T lymphocytes inhibits human immunodeficiency virus type 1 replication through STAT1 activation." Journal of Virology 76, no. 2 (January 2002): 569-581.  Full Text
    • Gusella, GL, Fedorova, E, Marras, D, Klotman, PE, and Klotman, ME. "In vivo gene transfer to kidney by lentiviral vector." Kidney International 61, no. SUPPL. 1 (January 1, 2002).  Full Text
    • Gusella, GL, Fedorova, E, Marras, D, Klotman, PE, and Klotman, ME. "In vivo gene transfer to kidney by lentiviral vector." Kidney International 61, no. 1 Suppl (January 2002): S32-S36.  Full Text
    • Stern, AS, Klotman, ME, Ioannou, YA, Burrow, CR, Wilson, PD, Klotman, PE, and Lipkowitz, MS. "Polarity of α-galactosidase A uptake by renal tubule cells." Kidney International 61, no. SUPPL. 1 (January 1, 2002).  Full Text
    • Stern, AS, Klotman, ME, Ioannou, YA, Burrow, CR, Wilson, PD, Klotman, PE, and Lipkowitz, MS. "Polarity of alpha-galactosidase A uptake by renal tubule cells." Kidney International 61, no. 1 Suppl (January 2002): S52-S55.  Full Text
    • Huprikar, SS, Datta, SD, Lang, L, and Klotman, ME. "Viral load and CD4 count as predictors of response to hepatitis B vaccine." Clinical Infectious Diseases 33, no. 7 (October 1, 2001): 1153-1153.  Link to Item
    • Schecter, AD, Berman, AB, Yi, L, Mosoian, A, McManus, CM, Berman, JW, Klotman, ME, and Taubman, MB. "HIV envelope gp120 activates human arterial smooth muscle cells." Proceedings of the National Academy of Sciences of the United States of America 98, no. 18 (August 14, 2001): 10142-10147.  Full Text
    • Jones, S, and Klotman, ME. "Impact of genotypic resistance testing on physician selection of antiretroviral therapy." Journal of Human Virology 4, no. 4 (July 2001): 214-216.
    • Winston, JA, Bruggeman, LA, Ross, MD, Jacobson, J, Ross, L, D'Agati, VD, Klotman, PE, and Klotman, ME. "Nephropathy and establishment of a renal reservoir of HIV type 1 during primary infection." The New England Journal of Medicine 344, no. 26 (June 2001): 1979-1984.  Full Text
    • Schecter, AD, Berman, AB, Yi, L, Berman, JW, Klotman, ME, and Taubman, MB. "Human immunodeficiency viral envelope protein, gp120, induces tissue factor activity in human arterial smooth muscle cells." Arteriosclerosis Thrombosis and Vascular Biology 21, no. 4 (April 1, 2001): 690-690.  Link to Item
    • Gillim, L, Gusella, GL, Vargas, J, Marras, D, Klotman, ME, and Cara, A. "Development of a novel screen for protease inhibitors." Clinical and Diagnostic Laboratory Immunology 8, no. 2 (March 2001): 437-440.  Full Text
    • Bruggeman, LA, Ross, MD, Tanji, N, Cara, A, Dikman, S, Gordon, RE, Burns, GC, D'Agati, VD, Winston, JA, Klotman, ME, and Klotman, PE. "Renal epithelium is a previously unrecognized site of HIV-1 infection." Journal of the American Society of Nephrology : Jasn 11, no. 11 (November 2000): 2079-2087.
    • Jacobson, JM, Lowy, I, Fletcher, CV, O'Neill, TJ, Tran, DN, Ketas, TJ, Trkola, A, Klotman, ME, Maddon, PJ, Olson, WC, and Israel, RJ. "Single-dose safety, pharmacology, and antiviral activity of the human immunodeficiency virus (HIV) type 1 entry inhibitor PRO 542 in HIV-infected adults." The Journal of Infectious Diseases 182, no. 1 (July 2000): 326-329.  Full Text
    • Jones, S, and Klotman, ME. "Access to genotypic resistance testing alters physician selection of antiretroviral therapy." Clinical Infectious Diseases 31, no. 1 (July 1, 2000): 275-275.  Link to Item
    • Tellier, MC, Greco, G, Klotman, M, Mosoian, A, Cara, A, Arap, W, Ruoslahti, E, Pasqualini, R, and Schnapp, LM. "Superfibronectin, a multimeric form of fibronectin, increases HIV infection of primary CD4+ T lymphocytes." Journal of Immunology (Baltimore, Md. : 1950) 164, no. 6 (March 2000): 3236-3245.  Full Text
    • Mosoian, A, Teixeira, A, Caron, E, Piwoz, J, and Klotman, ME. "CD8⁺ cell lines isolated from HIV-1-infected children have potent soluble HIV-1 inhibitory activity that differs from β-chemokines." Viral Immunology 13, no. 4 (2000): 481-495.
    • Mosoian, A, Teixeira, A, Caron, E, Piwoz, J, and Klotman, ME. "CD8+ cell lines isolated from HIV-1-infected children have potent soluble HIV-1 inhibitory activity that differs from beta-chemokines." Viral Immunology 13, no. 4 (January 2000): 481-495.  Full Text
    • Lipkowitz, MS, Hanss, B, Tulchin, N, Wilson, PD, Langer, JC, Ross, MD, Kurtzman, GJ, Klotman, PE, and Klotman, ME. "Transduction of renal cells in vitro and in vivo by adeno-associated virus gene therapy vectors." Journal of the American Society of Nephrology : Jasn 10, no. 9 (September 1999): 1908-1915.
    • Winston, JA, Klotman, ME, and Klotman, PE. "HIV-associated nephropathy is a late, not early, manifestation of HIV-1 infection." Kidney International 55, no. 3 (March 1999): 1036-1040. (Review)  Full Text
    • Klotman, M. "Potential role for G-protein coupled receptors in HIV-associated nephropathy." Kidney International 54, no. 6 (December 1998): 2243-2244. (Review)  Full Text
    • Gelfand, JM, Rudikoff, D, Lebwohl, M, and Klotman, ME. "Effect of UV-B phototherapy on plasma HIV type 1 RNA viral level: a self-controlled prospective study." Archives of Dermatology 134, no. 8 (August 1998): 940-945.  Full Text
    • Gurtman, A, Borrego, F, and Klotman, ME. "Management of antiretroviral therapy." Seminars in Nephrology 18, no. 4 (July 1998): 459-480. (Review)
    • Langer, JC, Klotman, ME, Hanss, B, Tulchin, N, Bruggeman, LA, Klotman, PE, and Lipkowitz, MS. "Adeno-associated virus gene transfer into renal cells: potential for in vivo gene delivery." Experimental Nephrology 6, no. 3 (May 1998): 189-194. (Review)
    • Rivadeneira, ED, Popescu, NC, Zimonjic, DB, Cheng, GS, Nelson, PJ, Ross, MD, DiPaolo, JA, and Klotman, ME. "Sites of recombinant adeno-associated virus integration." International Journal of Oncology 12, no. 4 (April 1998): 805-810.
    • Klotman, ME, and Klotman, PE. "Seminars in nephrology." Seminars in Nephrology 18, no. 4 (January 1, 1998): 371-372.
    • Snoeck, HW, Tao, W, and Klotman, ME. "Adeno-associated viral vectors: background and technical aspects." Experimental Nephrology 5, no. 6 (November 1997): 514-520. (Review)
    • Cereseto, A, Berneman, Z, Koralnik, I, Vaughn, J, Franchini, G, and Klotman, ME. "Differential expression of alternatively spliced pX mRNAs in HTLV-I-infected cell lines." Leukemia 11, no. 6 (June 1997): 866-870.  Full Text
    • Lipkowitz, MS, Klotman, ME, Bruggeman, LA, Nicklin, P, Hanss, B, Rappaport, J, and Klotman, PE. "Molecular therapy for renal diseases." American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation 28, no. 4 (October 1996): 475-492. (Review)  Full Text
    • Cereseto, A, Diella, F, Mulloy, JC, Cara, A, Michieli, P, Grassmann, R, Franchini, G, and Klotman, ME. "p53 functional impairment and high p21waf1/cip1 expression in human T-cell lymphotropic/leukemia virus type I-transformed T cells." Blood 88, no. 5 (September 1996): 1551-1560.
    • Bruggeman, LA, Thomson, MM, Nelson, PJ, Kopp, JB, Rappaport, J, Klotman, PE, and Klotman, ME. "Patterns of HIV-1 mRNA expression in transgenic mice are tissue-dependent." Virology 202, no. 2 (August 1994): 940-948.  Full Text
    • Santoro, TJ, Bryant, JL, Pellicoro, J, Klotman, ME, Kopp, JB, Bruggeman, LA, Franks, RR, Notkins, AL, and Klotman, PE. "Growth failure and AIDS-like cachexia syndrome in HIV-1 transgenic mice." Virology 201, no. 1 (May 1994): 147-151.  Full Text
    • Gallo, RC, and Klotman, ME. "1993 Annual Meeting of the Laboratory of Tumor Cell Biology: Introduction." Aids Research and Human Retroviruses 10, no. SUPPL. 1 (January 1, 1994).
    • Dhawan, S, Weeks, BS, Abbasi, F, Gralnick, HR, Notkins, AL, Klotman, ME, Yamada, KM, and Klotman, PE. "Increased expression of alpha 4 beta 1 and alpha 5 beta 1 integrins on HTLV-I-infected lymphocytes." Virology 197, no. 2 (December 1993): 778-781.  Full Text
    • Li, G, Lisziewicz, J, Sun, D, Zon, G, Daefler, S, Wong-Staal, F, Gallo, RC, and Klotman, ME. "Inhibition of Rev activity and human immunodeficiency virus type 1 replication by antisense oligodeoxynucleotide phosphorothioate analogs directed against the Rev-responsive element." Journal of Virology 67, no. 11 (November 1993): 6882-6888.
    • Weeks, BS, Klotman, ME, Holloway, E, Stetler-Stevenson, WG, Kleinman, HK, and Klotman, PE. "HIV-1 infection stimulates T cell invasiveness and synthesis of the 92-kDa type IV collagenase." Aids Research and Human Retroviruses 9, no. 6 (June 1993): 513-518.  Full Text
    • Weeks, BS, Desai, K, Loewenstein, PM, Klotman, ME, Klotman, PE, Green, M, and Kleinman, HK. "Identification of a novel cell attachment domain in the HIV-1 Tat protein and its 90-kDa cell surface binding protein." The Journal of Biological Chemistry 268, no. 7 (March 1993): 5279-5284.
    • Lisziewicz, J, Sun, D, Klotman, M, Agrawal, S, Zamecnik, P, and Gallo, R. "Specific inhibition of human immunodeficiency virus type 1 replication by antisense oligonucleotides: an in vitro model for treatment." Proceedings of the National Academy of Sciences of the United States of America 89, no. 23 (December 1992): 11209-11213.  Full Text
    • Koralnik, IJ, Gessain, A, Klotman, ME, Lo Monico, A, Berneman, ZN, and Franchini, G. "Protein isoforms encoded by the pX region of human T-cell leukemia/lymphotropic virus type I." Proceedings of the National Academy of Sciences of the United States of America 89, no. 18 (September 1992): 8813-8817.  Full Text
    • Perfect, JR, Klotman, ME, Gilbert, CC, Crawford, DD, Rosner, GL, Wright, KA, and Peters, WP. "Prophylactic intravenous amphotericin B in neutropenic autologous bone marrow transplant recipients." The Journal of Infectious Diseases 165, no. 5 (May 1992): 891-897.  Full Text
    • Berneman, ZN, Gartenhaus, RB, Reitz, MS, Blattner, WA, Manns, A, Hanchard, B, Ikehara, O, Gallo, RC, and Klotman, ME. "Expression of alternatively spliced human T-lymphotropic virus type I pX mRNA in infected cell lines and in primary uncultured cells from patients with adult T-cell leukemia/lymphoma and healthy carriers." Proceedings of the National Academy of Sciences of the United States of America 89, no. 7 (April 1992): 3005-3009.  Full Text
    • Kopp, JB, Klotman, ME, Adler, SH, Bruggeman, LA, Dickie, P, Marinos, NJ, Eckhaus, M, Bryant, JL, Notkins, AL, and Klotman, PE. "Progressive glomerulosclerosis and enhanced renal accumulation of basement membrane components in mice transgenic for human immunodeficiency virus type 1 genes." Proceedings of the National Academy of Sciences of the United States of America 89, no. 5 (March 1992): 1577-1581.  Full Text
    • Klotman, ME, Kim, SY, Buchbinder, A, DeRossi, A, Baltimore, D, and Wong-Staal, F. "Kinetics of expression of multiply spliced RNA in early human immunodeficiency virus type 1 infection of lymphocytes and monocytes." Proceedings of the National Academy of Sciences of the United States of America 89, no. 3 (February 1992): 1148-null.  Full Text
    • Berneman, ZN, Gartenhaus, RB, Reitz, MS, Klotman, ME, and Gallo, RC. "cDNA sequencing confirms HTLV-I expression in adult T-cell leukemia/lymphoma and different sequence variations in vivo and in vitro." Leukemia 6 Suppl 3 (January 1992): 67S-71S.
    • Klotman, ME, Kim, S, Buchbinder, A, DeRossi, A, Baltimore, D, and Wong-Staal, F. "Erratum: Kinetics of expression of multiply spliced RNA in early human immunodeficiency virus type 1 infection of lymphocytes and monocytes (Proc. Natl. Acad. Sci. USA (June 1991) 88 (5011-5015))." Proceedings of the National Academy of Sciences of the United States of America 89, no. 3 (January 1, 1992): 1148-null.
    • Gartenhaus, RB, Wong-Staal, F, and Klotman, ME. "The promoter of human T-cell leukemia virus type-I is repressed by the immediate-early gene region of human cytomegalovirus in primary blood lymphocytes." Blood 78, no. 11 (December 1991): 2956-2961.
    • Weeks, BS, Klotman, ME, Dhawan, S, Kibbey, M, Rappaport, J, Kleinman, HK, Yamada, KM, and Klotman, PE. "HIV-1 infection of human T lymphocytes results in enhanced alpha 5 beta 1 integrin expression." The Journal of Cell Biology 114, no. 4 (August 1991): 847-853.  Full Text
    • Klotman, ME, Kim, S, Buchbinder, A, DeRossi, A, Baltimore, D, and Wong-Staal, F. "Kinetics of expression of multiply spliced RNA in early human immunodeficiency virus type 1 infection of lymphocytes and monocytes." Proceedings of the National Academy of Sciences of the United States of America 88, no. 11 (June 1991): 5011-5015.  Full Text
    • Daefler, S, Klotman, ME, and Wong-Staal, F. "Trans-activating rev protein of the human immunodeficiency virus 1 interacts directly and specifically with its target RNA." Proceedings of the National Academy of Sciences of the United States of America 87, no. 12 (June 1990): 4571-4575.  Full Text
    • Shaunak, S, Albright, RE, Klotman, ME, Henry, SC, Bartlett, JA, and Hamilton, JD. "Amplification of HIV-1 provirus from cerebrospinal fluid and its correlation with neurologic disease." The Journal of Infectious Diseases 161, no. 6 (June 1990): 1068-1072.  Full Text
    • Sadaie, MR, Tschachler, E, Valerie, K, Rosenberg, M, Felber, BK, Pavlakis, GN, Klotman, ME, and Wong-Staal, F. "Activation of tat-defective human immunodeficiency virus by ultraviolet light." The New Biologist 2, no. 5 (May 1990): 479-486.
    • Klotman, ME, Henry, SC, Greene, RC, Brazy, PC, Klotman, PE, and Hamilton, JD. "Detection of mouse cytomegalovirus nucleic acid in latently infected mice by in vitro enzymatic amplification." The Journal of Infectious Diseases 161, no. 2 (February 1990): 220-225.  Full Text
    • Kim, JH, Cooper, RA, Welty-Wolf, KE, Harrell, LJ, Zwadyk, P, and Klotman, ME. "Pseudomonas putrefaciens bacteremia." Reviews of Infectious Diseases 11, no. 1 (January 1989): 97-104.
    • Peters, WP, Stuart, A, Klotman, M, Gilbert, C, Jones, RB, Shpall, EJ, Gockerman, J, Bast, RC, and Moore, JO. "High-dose combination cyclophosphamide, cisplatin, and melphalan with autologous bone marrow support. A clinical and pharmacologic study." Cancer Chemotherapy and Pharmacology 23, no. 6 (January 1989): 377-383.  Full Text
    • Schmader, KE, van der Horst, CM, and Klotman, ME. "Epstein-Barr virus and the elderly host." Reviews of Infectious Diseases 11, no. 1 (January 1989): 64-73. (Review)
    • Buchbinder, A, Josephs, SF, Ablashi, D, Salahuddin, SZ, Klotman, ME, Manak, M, Krueger, GR, Wong-Staal, F, and Gallo, RC. "Polymerase chain reaction amplification and in situ hybridization for the detection of human B-lymphotropic virus." Journal of Virological Methods 21, no. 1-4 (September 1988): 191-197.  Full Text
    • Klotman, ME, Henry, SC, and Hamilton, JD. "Determinants of the source of cytomegalovirus in murine renal allograft recipients." Transplantation 44, no. 5 (November 1987): 636-639.
    • Klotman, ME, and Hamilton, JD. "Cytomegalovirus pneumonia." Seminars in Respiratory Infections 2, no. 2 (June 1987): 95-103. (Review)
    • Klotman, ME, Starnes, D, and Hamilton, JD. "The source of murine cytomegalovirus in mice receiving kidney allografts." The Journal of Infectious Diseases 152, no. 6 (December 1985): 1192-1196.  Full Text
    • Klotman, ME. "Laboratory detection of urinary tract infections." Kidney 18, no. 1 (January 1, 1985): 1-4.

  • Conference Papers

    • Blasi, M, Negri, D, Santra, S, Parks, R, Shen, X, Tomaras, G, Permar, S, Montefiori, D, LaBranche, C, Ferrari, G, Alam, M, Liao, H, Moody, AM, Haynes, BF, Klotman, ME, and Cara, A. "A Single Immunization with Integrase Defective Lentiviral Vector Expressing gp140 Induces Persistent and Functional Immune Response in Rhesus Monkeys." Conference on AIDS Vaccine. Barcelona, SPAIN. October 7, 2013 - October 10, 2013.: MARY ANN LIEBERT, INC, November 1, 2013.  Link to Item
    • Tuyama, AC, Hong, F, Schecter, AD, Mosoian, A, Chen, BK, Chen, P, Klotman, ME, and Bansal, MB. "HIV entry and replication stellate cells promotes cellular activation and fibrogenesis: Implications for hepatic fibrosis in HIV/HCV co-infection." 58th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases. Boston, MA. November 2, 2007 - November 6, 2007.: JOHN WILEY & SONS INC, October 1, 2007.  Link to Item
    • Zerhouni-Layachi, B, Marras, D, Francois, F, Klotman, PE, and Klotman, ME. "Phenotypic characterization of HIV-1 envelopes derived from patients with HIVAN." 36th Annual Meeting of the American-Society-of-Nephrology. SAN DIEGO, CALIFORNIA. November 12, 2003 - November 17, 2003.: LIPPINCOTT WILLIAMS & WILKINS, November 1, 2003.  Link to Item
    • Cara, A, Vargas, J, Keller, M, Jones, S, Mosoian, A, Gurtman, A, Cohen, A, Parkas, V, Wallach, F, Chusid, E, Gelman, IH, and Klotman, ME. "Circular viral DNA and anomalous junction sequence in PBMC of HIV-infected individuals with no detectable plasma HIV RNA." January 2002.  Full Text
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