Mary E Klotman | Scholars@Duke

Mary E Klotman
R.J. Reynolds Professor of Medicine

Dr. Klotman became dean of the Duke School of Medicine in June 2017.

An accomplished clinician and scientist, Klotman’s research interests are focused on the molecular pathogenesis of Human Immunodeficiency Virus 1 (HIV-1) infection.

Among many important contributions to this field, Klotman and her team demonstrated that HIV resides in and evolves separately in kidney cells, a critical step in HIV-associated kidney disease. Her research group also has determined the role of soluble host factors involved in an innate immune response to HIV in an effort to improve prevention strategies, topical microbicides that could be used to block sexual transmission of HIV.

Most recently, her group has been defining the role of integrase-defective lentiviral vectors for the delivery of an HIV vaccine. (Read the announcement. )

Current Appointments & Affiliations

R.J. Reynolds Professor of Medicine, Medicine, Infectious Diseases, Medicine 2011
Professor of Medicine, Medicine, Infectious Diseases, Medicine 2010
Dean, School of Medicine, School of Medicine, Duke University 2017
Professor in Molecular Genetics and Microbiology, Molecular Genetics and Microbiology, Basic Science Departments 2011
Professor of Pathology, Pathology, Clinical Science Departments 2013
Member of the Duke Human Vaccine Institute, Duke Human Vaccine Institute, Institutes and Centers 2010

Contact Information

DUMC 2927, Davison Building Room 125, Durham, NC 27710
Davison Building Room 125, Box 2927, Durham, NC 27710
mary.klotman@duke.edu (919) 684-2455
Department of Medicine - Leadership

Background
Education, Training, & Certifications
- Fellow in Infectious Diseases, Medicine, Duke University 1983 - 1985
- Resident, Medicine, Duke University 1980 - 1983
- M.D., Duke University 1980
Duke Appointment History
- Chair, Department of Medicine, Medicine, Clinical Science Departments 2010 - 2017
- Consulting Associate in the Department of Medicine, Medicine, Infectious Diseases, Medicine 2010
- Assistant Professor, Medicine, Clinical Science Departments 1986 - 1990
- Associate, Medicine, Clinical Science Departments 1985 - 1986
Recognition
In the News
- MAY 18, 2018 Viewpoints podcast
  
  What's Duke Doing to Better Understand and Treat Brain Diseases?
- MAR 5, 2018 Viewpoints podcast
  
  Why is it Important to Explore the Early-life Origins of Health and Disease?
- JAN 19, 2018 Viewpoint podcast
  
  Dean Mary Klotman on Translating Duke Health
- NOV 2, 2017 School of Medicine Viewpoint Podcast
  
  Mary Klotman: What Did it Take to Change HIV From a Fatal Diagnosis to an Often-manageable, Disease?
- OCT 10, 2017 School of Medicine Viewpoint
  
  Mary Klotman: What is Data Science and Why Is It Important?
- AUG 29, 2017
  
  Dr. Mary Klotman: Why Diversity Is Necessary in Academic Medicine
- JUL 11, 2017
  
  From Undergraduate to Dean: Dr. Mary Klotman Describes What She Has Learned at Duke
- MAY 25, 2017 School of Medicine
  
  Duke Hosts Precision Medicine World Conference
- APR 24, 2017 Duke School of Medicine
  
  Klotman Joins Roundtable Discussion with Rep. David Price to Discuss NIH Budget
- JAN 30, 2017
  
  Dr. Mary Klotman Named Dean of Duke School of Medicine
- APR 6, 2015 The News & Observer
  
  Duke HIV researchers receive large federal grants
- APR 5, 2015
  
  Duke Research Teams Win Large Federal Grants for HIV Vaccine Studies
- OCT 21, 2014
  
  Klotman, chair of Medicine, Named to Institute of Medicine
Awards & Honors
- Member. Institute of Medicine of The National Academies. 2014
- Membership. National Academy of Medicine. 2014
Expertise
Subject Headings
Research
Selected Grants
- Persistent HIV Infection in the Kidney awarded by Baylor College of Medicine 1999 - 2022
- Mentoring Patient Oriented Research in Antibiotic-Resistant Bacteria awarded by National Institutes of Health 2011 - 2021
- Interdisciplinary Research Training Program in AIDS awarded by National Institutes of Health 2010 - 2020
- The Genitourinary Tract as a compartment and reservoir for HIV awarded by National Institutes of Health 2015 - 2020
- Integrase Defective Lentiviral Vector (IDLV) for HIV Vaccine Development awarded by National Institutes of Health 2015 - 2020
- Viral Oncology Training Grant awarded by National Institutes of Health 1980 - 2019
- Systems Biology Approaches for Predicting Cardiometabolic Risk in Persons Living with HIV awarded by National Institutes of Health 2015 - 2018
- Serial Block Face Scanning Electron Microscope awarded by National Institutes of Health 2016 - 2018
- Impact of polyploidy on establishing an HIV-1 reservoir in the kidney awarded by University of Alabama at Birmingham 2014 - 2017
- The Pathogenesis of HIV-Associated Nephropathy awarded by Baylor College of Medicine 2011 - 2016
Publications & Artistic Works
Selected Publications
- Conference Papers
  - Blasi, M, Negri, D, Santra, S, Parks, R, Shen, X, Tomaras, G, Permar, S, Montefiori, D, LaBranche, C, Ferrari, G, Alam, M, Liao, H, Moody, AM, Haynes, BF, Klotman, ME, and Cara, A. "A Single Immunization with Integrase Defective Lentiviral Vector Expressing gp140 Induces Persistent and Functional Immune Response in Rhesus Monkeys." November 1, 2013. Link to Item
  - Tuyama, AC, Hong, F, Schecter, AD, Mosoian, A, Chen, BK, Chen, P, Klotman, ME, and Bansal, MB. "HIV entry and replication stellate cells promotes cellular activation and fibrogenesis: Implications for hepatic fibrosis in HIV/HCV co-infection." October 2007. Link to Item
  - Zerhouni-Layachi, B, Marras, D, Francois, F, Klotman, PE, and Klotman, ME. "Phenotypic characterization of HIV-1 envelopes derived from patients with HIVAN." November 2003. Link to Item
  - Cara, A, Vargas, J, Keller, M, Jones, S, Mosoian, A, Gurtman, A, Cohen, A, Parkas, V, Wallach, F, Chusid, E, Gelman, IH, and Klotman, ME. "Circular viral DNA and anomalous junction sequence in PBMC of HIV-infected individuals with no detectable plasma HIV RNA." January 5, 2002. Full Text Link to Item
- Journal Articles
  - Payne, EH, Ramalingam, D, Fox, DT, and Klotman, ME. "Polyploidy and Mitotic Cell Death Are Two Distinct HIV-1 Vpr-Driven Outcomes in Renal Tubule Epithelial Cells." Journal of virology 92, no. 2 (January 2018). Full Text
  - Negri, D, Blasi, M, LaBranche, C, Parks, R, Balachandran, H, Lifton, M, Shen, X, Denny, T, Ferrari, G, Vescio, MF, Andersen, H, Montefiori, DC, Tomaras, GD, Liao, H-X, Santra, S, Haynes, BF, Klotman, ME, and Cara, A. "Immunization with an SIV-based IDLV Expressing HIV-1 Env 1086 Clade C Elicits Durable Humoral and Cellular Responses in Rhesus Macaques." Molecular therapy : the journal of the American Society of Gene Therapy 24, no. 11 (November 2016): 2021-2032. Full Text Open Access Copy
  - Chen, P, Yi, Z, Zhang, W, Klotman, ME, and Chen, BK. "HIV infection-induced transcriptional program in renal tubular epithelial cells activates a CXCR2-driven CD4+ T-cell chemotactic response." AIDS (London, England) 30, no. 12 (July 2016): 1877-1888. Full Text
  - Blasi, M, Carpenter, JH, Balakumaran, B, Cara, A, Gao, F, and Klotman, ME. "Identification of HIV-1 genitourinary tract compartmentalization by analyzing the env gene sequences in urine." AIDS (London, England) 29, no. 13 (August 2015): 1651-1657. Full Text
  - Michelini, Z, Negri, D, Biava, M, Baroncelli, S, Spada, M, Leone, P, Bona, R, Blasi, M, Nègre, D, Klotman, ME, and Cara, A. "Murine granulocyte-macrophage colony-stimulating factor expressed from a bicistronic simian immunodeficiency virus-based integrase-defective lentiviral vector does not enhance T-cell responses in mice." Viral immunology 27, no. 10 (December 2014): 512-520. Full Text
  - Carethers, JM, Coughlin, S, Diamond, B, Erzurum, S, Fried, LP, Jameson, JL, Kaushansky, K, Klotman, ME, Lemon, S, Mitchell, B, Rothman, P, Sawyers, C, Seidman, C, and Somlo, S. "The imperative to invest in science has never been greater." The Journal of clinical investigation 124, no. 11 (November 2014): 5085-. Full Text
  - Blasi, M, Balakumaran, B, Chen, P, Negri, DRM, Cara, A, Chen, BK, and Klotman, ME. "Renal epithelial cells produce and spread HIV-1 via T-cell contact." AIDS (London, England) 28, no. 16 (October 2014): 2345-2353. Full Text
  - Carethers, JM, Coughlin, S, Diamond, B, Erzurum, S, Fried, LP, Jameson, JL, Kaushansky, K, Klotman, ME, Lemon, S, Mitchell, B, Rothman, P, Sawyers, C, Seidman, C, and Somlo, S. "The imperative to invest in science has never been greater." Journal of Clinical Investigation 124, no. 9 (September 2, 2014): 3680-3681. Full Text
  - Blasi, M, Balakumaran, B, Chen, P, Negri, DRM, Cara, A, Chen, BK, and Klotman, ME. "Renal epithelial cells produce and spread HIV-1 via T-cell contact." AIDS 28, no. 16 (January 1, 2014): 2345-2353. Full Text
  - Rossi, A, Michelini, Z, Leone, P, Borghi, M, Blasi, M, Bona, R, Spada, M, Grasso, F, Gugliotta, A, Klotman, ME, Cara, A, and Negri, D. "Optimization of mucosal responses after intramuscular immunization with integrase defective lentiviral vector." PloS one 9, no. 9 (January 2014): e107377-. Full Text
  - Micsenyi, AM, Zony, C, Alvarez, RA, Durham, ND, Chen, BK, and Klotman, ME. "Postintegration HIV-1 infection of cervical epithelial cells mediates contact-dependent productive infection of T cells." J Infect Dis 208, no. 11 (December 1, 2013): 1756-1767. Full Text Link to Item
  - Hutter, R, Huang, L, Speidl, WS, Giannarelli, C, Trubin, P, Bauriedel, G, Klotman, ME, Fuster, V, Badimon, JJ, and Klotman, PE. "Novel small leucine-rich repeat protein podocan is a negative regulator of migration and proliferation of smooth muscle cells, modulates neointima formation, and is expressed in human atheroma." Circulation 128, no. 22 (November 26, 2013): 2351-2363. Full Text
  - Hutter, R, Huang, L, Speidl, WS, Giannarelli, C, Trubin, P, Bauriedel, G, Klotman, ME, Fuster, V, Badimon, JJ, and Klotman, PE. "Novel small leucine-rich repeat protein podocan is a negative regulator of migration and proliferation of smooth muscle cells, modulates neointima formation, and is expressed in human atheroma." Circulation 128, no. 22 (November 26, 2013): 2351-2363. Full Text Link to Item
  - Todd, RF, Salata, RA, Klotman, ME, Weisfeldt, ML, Katz, JT, Xian, SX, Hearn, DP, and Lipner, RS. "Career outcomes of the graduates of the American Board of Internal Medicine Research Pathway, 1995-2007." Acad Med 88, no. 11 (November 2013): 1747-1753. Full Text Link to Item
  - Todd, RF, Salata, RA, Klotman, ME, Weisfeldt, ML, Katz, JT, Xian, SX, Hearn, DP, and Lipner, RS. "Career outcomes of the graduates of the American board of internal medicine research pathway, 1995-2007." Academic Medicine 88, no. 11 (January 1, 2013): 1747-1753. Full Text
  - Blasi, M, Rossi, A, Michelini, Z, Leone, P, Perretta, G, Cimarelli, A, Klotman, ME, Negri, D, and Cara, A. "Simian immunodeficiency virus-Vpx as an adjuvant for integrase defective lentiviral vector-based vaccines." RETROVIROLOGY 9 (September 13, 2012). Full Text Link to Item
  - Negri, DRM, Rossi, A, Blasi, M, Michelini, Z, Leone, P, Chiantore, MV, Baroncelli, S, Perretta, G, Cimarelli, A, Klotman, ME, and Cara, A. "Simian immunodeficiency virus-Vpx for improving integrase defective lentiviral vector-based vaccines. (Published online)" Retrovirology 9 (August 22, 2012): 69-. Full Text Link to Item
  - Papeta, N, Kiryluk, K, Patel, A, Sterken, R, Kacak, N, Snyder, HJ, Imus, PH, Mhatre, AN, Lawani, AK, Julian, BA, Wyatt, RJ, Novak, J, Wyatt, CM, Ross, MJ, Winston, JA, Klotman, ME, Cohen, DJ, Appel, GB, D'Agati, VD, Klotman, PE, and Gharavi, AG. "APOL1 variants increase risk for FSGS and HIVAN but not IgA nephropathy." J Am Soc Nephrol 22, no. 11 (November 2011): 1991-1996. Full Text Link to Item
  - Chen, P, Chen, BK, Mosoian, A, Hays, T, Ross, MJ, Klotman, PE, and Klotman, ME. "Virological synapses allow HIV-1 uptake and gene expression in renal tubular epithelial cells." J Am Soc Nephrol 22, no. 3 (March 2011): 496-507. Full Text Link to Item
  - Ding, J, Rapista, A, Teleshova, N, Lu, W, Klotman, ME, and Chang, TL. "Mucosal human defensins 5 and 6 antagonize the anti-HIV activity of candidate polyanion microbicides." J Innate Immun 3, no. 2 (2011): 208-212. Full Text Link to Item
  - Jao, J, Palmer, D, Leus, I, Tih, P, Baweja, M, Klotman, M, Sperling, R, and Wyatt, C. "Prevalence and predictors of proteinuria in HIV-infected and uninfected pregnant women in Cameroon." Nephrology Dialysis Transplantation 26, no. 9 (2011): 3051-3053. Full Text
  - Negri, DRM, Bona, R, Michelini, Z, Leone, P, Macchia, I, Klotman, ME, Salvatore, M, and Cara, A. "Transduction of human antigen-presenting cells with integrase-defective lentiviral vector enables functional expansion of primed antigen-specific CD8(+) T cells." Hum Gene Ther 21, no. 8 (August 2010): 1029-1035. Full Text Link to Item
  - Tuyama, AC, Hong, F, Saiman, Y, Wang, C, Ozkok, D, Mosoian, A, Chen, P, Chen, BK, Klotman, ME, and Bansal, MB. "Human immunodeficiency virus (HIV)-1 infects human hepatic stellate cells and promotes collagen I and monocyte chemoattractant protein-1 expression: implications for the pathogenesis of HIV/hepatitis C virus-induced liver fibrosis." Hepatology 52, no. 2 (August 2010): 612-622. Full Text Link to Item
  - Mosoian, A, Teixeira, A, Burns, CS, Sander, LE, Gusella, GL, He, C, Blander, JM, Klotman, P, and Klotman, ME. "Prothymosin-alpha inhibits HIV-1 via Toll-like receptor 4-mediated type I interferon induction." Proc Natl Acad Sci U S A 107, no. 22 (June 1, 2010): 10178-10183. Full Text Link to Item
  - Snyder, A, Alsauskas, ZC, Leventhal, JS, Rosenstiel, PE, Gong, P, Chan, JJK, Barley, K, He, JC, Klotman, ME, Ross, MJ, and Klotman, PE. "HIV-1 viral protein r induces ERK and caspase-8-dependent apoptosis in renal tubular epithelial cells." AIDS 24, no. 8 (May 15, 2010): 1107-1119. Full Text Link to Item
  - Ding, J, Rapista, A, Teleshova, N, Mosoyan, G, Jarvis, GA, Klotman, ME, and Chang, TL. "Neisseria gonorrhoeae enhances HIV-1 infection of primary resting CD4+ T cells through TLR2 activation." J Immunol 184, no. 6 (March 15, 2010): 2814-2824. Full Text Link to Item
  - Chang, TL, and Klotman, M. "Defensins and HIV infection." Soluble Factors Mediating Innate Immune Responses to HIV Infection (2010): 51-63. Full Text
  - Negri, DRM, Michelini, Z, Baroncelli, S, Spada, M, Vendetti, S, Bona, R, Leone, P, Klotman, ME, and Cara, A. "Nonintegrating Lentiviral Vector-Based Vaccine Efficiently Induces Functional and Persistent CD8+ T Cell Responses in Mice." J Biomed Biotechnol 2010 (2010): 534501-. Full Text Link to Item
  - Snyder, A, Alsauskas, Z, Gong, P, Rosenstiel, PE, Klotman, ME, Klotman, PE, and Ross, MJ. "FAT10: a novel mediator of Vpr-induced apoptosis in human immunodeficiency virus-associated nephropathy." J Virol 83, no. 22 (November 2009): 11983-11988. Full Text Link to Item
  - Factor, SH, and Klotman, ME. "Zoonotic infections: an emerging threat to human health." Mt Sinai J Med 76, no. 5 (October 2009): 419-420. Full Text Link to Item
  - Rosenstiel, PE, Chan, J, Snyder, A, Planelles, V, D'Agati, VD, Klotman, PE, and Klotman, ME. "HIV-1 Vpr activates the DNA damage response in renal tubule epithelial cells." AIDS 23, no. 15 (September 24, 2009): 2054-2056. Full Text Link to Item
  - Chen, W-H, Janout, V, Kondo, M, Mosoian, A, Mosoyan, G, Petrov, RR, Klotman, ME, and Regen, SL. "A fine line between molecular umbrella transport and ionophoric activity." Bioconjug Chem 20, no. 9 (September 2009): 1711-1715. Full Text Link to Item
  - Michelini, Z, Negri, DRM, Baroncelli, S, Spada, M, Leone, P, Bona, R, Klotman, ME, and Cara, A. "Development and use of SIV-based Integrase defective lentiviral vector for immunization." Vaccine 27, no. 34 (July 23, 2009): 4622-4629. Full Text Link to Item
  - Sachdev, DD, Zerhouni-Layachi, B, Ortigoza, M, Profy, AT, Tuen, M, Hioe, CE, and Klotman, ME. "The differential binding and activity of PRO 2000 against diverse HIV-1 envelopes." J Acquir Immune Defic Syndr 51, no. 2 (June 1, 2009): 125-129. Full Text Link to Item
  - Wyatt, CM, Morgello, S, Katz-Malamed, R, Wei, C, Klotman, ME, Klotman, PE, and D'Agati, VD. "The spectrum of kidney disease in patients with AIDS in the era of antiretroviral therapy." Kidney Int 75, no. 4 (February 2009): 428-434. Full Text Link to Item
  - Abbadessa, G, Accolla, R, Aiuti, F, Albini, A, Aldovini, A, Alfano, M, Antonelli, G, Bartholomew, C, Bentwich, Z, Bertazzoni, U, Berzofsky, JA, Biberfeld, P, Boeri, E, Buonaguro, L, Buonaguro, FM, Bukrinsky, M, Burny, A, Caruso, A, Cassol, S, Chandra, P, Ceccherini-Nelli, L, Chieco-Bianchi, L, Clerici, M, Colombini-Hatch, S, de Giuli Morghen, C, de Maria, A, de Rossi, A, Dierich, M, Della-Favera, R, Dolei, A, Douek, D, Erfle, V, Felber, B, Fiorentini, S, Franchini, G, Gershoni, JM, and Gotch, F et al. "Unsung hero Robert C. Gallo." Science 323, no. 5911 (January 9, 2009): 206-207. (Letter) Full Text Link to Item
  - Feng, X, Lu, T-C, Chuang, PY, Fang, W, Ratnam, K, Xiong, H, Ouyang, X, Shen, Y, Levy, DE, Hyink, D, Klotman, M, D'Agati, V, Iyengar, R, Klotman, PE, and He, JC. "Reduction of Stat3 activity attenuates HIV-induced kidney injury." Journal of the American Society of Nephrology 20, no. 10 (2009): 2138-2146. Full Text
  - Vargas, J, Klotman, ME, and Cara, A. "Conditionally replicating lentiviral-hybrid episomal vectors for suicide gene therapy." Antiviral Res 80, no. 3 (December 2008): 288-294. Full Text Link to Item
  - Rosenstiel, PE, Gruosso, T, Letourneau, AM, Chan, JJ, LeBlanc, A, Husain, M, Najfeld, V, Planelles, V, D'Agati, VD, Klotman, ME, and Klotman, PE. "HIV-1 Vpr inhibits cytokinesis in human proximal tubule cells." Kidney Int 74, no. 8 (October 2008): 1049-1058. Full Text Link to Item
  - Klotman, ME, Rapista, A, Teleshova, N, Micsenyi, A, Jarvis, GA, Lu, W, Porter, E, and Chang, TL. "Neisseria gonorrhoeae-induced human defensins 5 and 6 increase HIV infectivity: role in enhanced transmission." J Immunol 180, no. 9 (May 1, 2008): 6176-6185. Link to Item
  - Teleshova, N, Chang, T, Profy, A, and Klotman, ME. "Inhibitory effect of PRO 2000, a candidate microbicide, on dendritic cell-mediated human immunodeficiency virus transfer." Antimicrob Agents Chemother 52, no. 5 (May 2008): 1751-1758. Full Text Link to Item
  - Eugenin, EA, Morgello, S, Klotman, ME, Mosoian, A, Lento, PA, Berman, JW, and Schecter, AD. "Human immunodeficiency virus (HIV) infects human arterial smooth muscle cells in vivo and in vitro: implications for the pathogenesis of HIV-mediated vascular disease." Am J Pathol 172, no. 4 (April 2008): 1100-1111. Full Text Link to Item
  - Radbill, BD, Wyatt, CM, Vassalotti, JA, Klotman, ME, and Klotman, PE. "Hepatitis B- and HIV-Related Renal Diseases." Therapy in Nephrology & Hypertension (2008): 272-280. Full Text
  - Chang, TL, Teleshova, N, Rapista, A, Paluch, M, Anderson, RA, Waller, DP, Zaneveld, LJD, Granelli-Piperno, A, and Klotman, ME. "SAMMA, a mandelic acid condensation polymer, inhibits dendritic cell-mediated HIV transmission." FEBS Lett 581, no. 24 (October 2, 2007): 4596-4602. Full Text Link to Item
  - Wyatt, CM, Winston, JA, Malvestutto, CD, Fishbein, DA, Barash, I, Cohen, AJ, Klotman, ME, and Klotman, PE. "Chronic kidney disease in HIV infection: an urban epidemic." AIDS 21, no. 15 (October 1, 2007): 2101-2103. Full Text Link to Item
  - Salvatore, M, Garcia-Sastre, A, Ruchala, P, Lehrer, RI, Chang, T, and Klotman, ME. "alpha-Defensin inhibits influenza virus replication by cell-mediated mechanism(s)." J Infect Dis 196, no. 6 (September 15, 2007): 835-843. Full Text Link to Item
  - Negri, DRM, Michelini, Z, Baroncelli, S, Spada, M, Vendetti, S, Buffa, V, Bona, R, Leone, P, Klotman, ME, and Cara, A. "Successful immunization with a single injection of non-integrating lentiviral vector." Mol Ther 15, no. 9 (September 2007): 1716-1723. Full Text Link to Item
  - Negri, DRM, Michelini, Z, Baroncelli, S, Spada, M, Vendetti, S, Buffa, V, Bona, R, Leone, P, Klotman, ME, and Cara, A. "Successful immunization with a single injection of non-integrating lentiviral vector." MOLECULAR THERAPY 15, no. 9 (September 2007): 1716-1723. Full Text Link to Item
  - Kaufman, L, Yang, G, Hayashi, K, Ashby, JR, Huang, L, Ross, MJ, Klotman, ME, and Klotman, PE. "The homophilic adhesion molecule sidekick-1 contributes to augmented podocyte aggregation in HIV-associated nephropathy." FASEB J 21, no. 7 (May 2007): 1367-1375. Full Text Link to Item
  - Bhadelia, N, Klotman, M, and Caplivski, D. "The HIV-Positive Traveler." American Journal of Medicine 120, no. 7 (2007): 574-580. Full Text
  - Mosoian, A, Teixeira, A, Burns, CS, Khitrov, G, Zhang, W, Gusella, L, Klotman, P, and Klotman, M. "Influence of prothymosin-α on HIV-1 target cells." Annals of the New York Academy of Sciences 1112 (2007): 269-285. Full Text
  - Cara, A, and Klotman, ME. "Retroviral E-DNA: persistence and gene expression in nondividing immune cells." J Leukoc Biol 80, no. 5 (November 2006): 1013-1017. (Review) Full Text Link to Item
  - Liu, X, Mosoian, A, Li-Yun Chang, T, Zerhouni-Layachi, B, Snyder, A, Jarvis, GA, and Klotman, ME. "Gonococcal lipooligosaccharide suppresses HIV infection in human primary macrophages through induction of innate immunity." J Infect Dis 194, no. 6 (September 15, 2006): 751-759. Full Text Link to Item
  - Tuyama, ACG, Cheshenko, N, Carlucci, MJ, Li, J-H, Goldberg, CL, Waller, DP, Anderson, RA, Profy, AT, Klotman, ME, Keller, MJ, and Herold, BC. "ACIDFORM inactivates herpes simplex virus and prevents genital herpes in a mouse model: optimal candidate for microbicide combinations." J Infect Dis 194, no. 6 (September 15, 2006): 795-803. Full Text Link to Item
  - Klotman, ME, and Chang, TL. "Defensins in innate antiviral immunity." Nat Rev Immunol 6, no. 6 (June 2006): 447-456. (Review) Full Text Link to Item
  - Ross, MJ, Fan, C, Ross, MD, Chu, T-H, Shi, Y, Kaufman, L, Zhang, W, Klotman, ME, and Klotman, PE. "HIV-1 infection initiates an inflammatory cascade in human renal tubular epithelial cells." J Acquir Immune Defic Syndr 42, no. 1 (May 2006): 1-11. Full Text Link to Item
  - Ross, MJ, Wosnitzer, MS, Ross, MD, Granelli, B, Gusella, GL, Husain, M, Kaufman, L, Vasievich, M, D'Agati, VD, Wilson, PD, Klotman, ME, and Klotman, PE. "Role of ubiquitin-like protein FAT10 in epithelial apoptosis in renal disease." J Am Soc Nephrol 17, no. 4 (April 2006): 996-1004. Full Text Link to Item
  - Dhawan, D, Keller, M, and Klotman, ME. "Topical microbicides: the time has come." AIDS Read 16, no. 3 (March 2006): 144-161. (Review) Link to Item
  - Fierer, DS, and Klotman, ME. "Kidney and central nervous system as reservoirs of HIV infection." Curr Opin HIV AIDS 1, no. 2 (March 2006): 115-120. Full Text Link to Item
  - Wyatt, CM, Arons, RR, Klotman, PE, and Klotman, ME. "Acute renal failure in hospitalized patients with HIV: risk factors and impact on in-hospital mortality." AIDS 20, no. 4 (February 28, 2006): 561-565. Full Text Link to Item
  - Zerhouni-Layachi, B, Husain, M, Ross, MJ, Marras, D, Sunamoto, M, Liu, X, Klotman, PE, and Klotman, ME. "Dual tropism of HIV-1 envelopes derived from renal tubular epithelial cells of patients with HIV-associated nephropathy." AIDS 20, no. 4 (February 28, 2006): 621-624. Full Text Link to Item
  - Keller, MJ, Zerhouni-Layachi, B, Cheshenko, N, John, M, Hogarty, K, Kasowitz, A, Goldberg, CL, Wallenstein, S, Profy, AT, Klotman, ME, and Herold, BC. "PRO 2000 gel inhibits HIV and herpes simplex virus infection following vaginal application: a double-blind placebo-controlled trial." J Infect Dis 193, no. 1 (January 1, 2006): 27-35. Full Text Link to Item
  - Mosoian, A, Teixeira, A, High, AA, Christian, RE, Hunt, DF, Shabanowitz, J, Liu, X, and Klotman, M. "Novel function of prothymosin alpha as a potent inhibitor of human immunodeficiency virus type 1 gene expression in primary macrophages." Journal of Virology 80, no. 18 (2006): 9200-9206. Full Text
  - Husain, M, D'Agati, VD, He, JC, Klotman, ME, and Klotman, PE. "HIV-1 Nef induces dedifferentiation of podocytes in vivo: a characteristic feature of HIVAN." AIDS 19, no. 17 (November 18, 2005): 1975-1980. Link to Item
  - John, M, Keller, MJ, Fam, EH, Cheshenko, N, Hogarty, K, Kasowitz, A, Wallenstein, S, Carlucci, MJ, Tuyama, AC, Lu, W, Klotman, ME, Lehrer, RI, and Herold, BC. "Cervicovaginal secretions contribute to innate resistance to herpes simplex virus infection." J Infect Dis 192, no. 10 (November 15, 2005): 1731-1740. Full Text Link to Item
  - Scordi-Bello, IA, Mosoian, A, He, C, Chen, Y, Cheng, Y, Jarvis, GA, Keller, MJ, Hogarty, K, Waller, DP, Profy, AT, Herold, BC, and Klotman, ME. "Candidate sulfonated and sulfated topical microbicides: comparison of anti-human immunodeficiency virus activities and mechanisms of action." Antimicrob Agents Chemother 49, no. 9 (September 2005): 3607-3615. Full Text Link to Item
  - Schwartz, EJ, Szczech, LA, Ross, MJ, Klotman, ME, Winston, JA, and Klotman, PE. "Highly active antiretroviral therapy and the epidemic of HIV+ end-stage renal disease." J Am Soc Nephrol 16, no. 8 (August 2005): 2412-2420. Full Text Link to Item
  - Chang, TL, Vargas, J, DelPortillo, A, and Klotman, ME. "Dual role of alpha-defensin-1 in anti-HIV-1 innate immunity." J Clin Invest 115, no. 3 (March 2005): 765-773. Full Text Link to Item
  - Gillim-Ross, L, Cara, A, and Klotman, ME. "Nef expressed from human immunodeficiency virus type 1 extrachromosomal DNA downregulates CD4 on primary CD4+ T lymphocytes: implications for integrase inhibitors." J Gen Virol 86, no. Pt 3 (March 2005): 765-771. Full Text Link to Item
  - Chang, TL, Jr, JV, DelPortillo, A, and Klotman, ME. "Dual role of α-defensin-1 in anti-HIV-1 innate immunity." Journal of Clinical Investigation 115, no. 3 (2005): 765-773. Full Text
  - Gillim-Ross, L, Cara, A, and Klotman, ME. "HIV-1 extrachromosomal 2-LTR circular DNA is long-lived in human macrophages." Viral Immunol 18, no. 1 (2005): 190-196. Full Text Link to Item
  - Jing, B, Janout, V, Herold, BC, Klotman, ME, Heald, T, and Regen, SL. "Persulfated molecular umbrellas as anti-HIV and anti-HSV agents." J Am Chem Soc 126, no. 49 (December 15, 2004): 15930-15931. Full Text Link to Item
  - He, JC, Husain, M, Sunamoto, M, D'Agati, VD, Klotman, ME, Iyengar, R, and Klotman, PE. "Nef stimulates proliferation of glomerular podocytes through activation of Src-dependent Stat3 and MAPK1,2 pathways." J Clin Invest 114, no. 5 (September 2004): 643-651. Full Text Link to Item
  - Chang, TL, and Klotman, ME. "Defensins: natural anti-HIV peptides." AIDS Rev 6, no. 3 (July 2004): 161-168. (Review) Link to Item
  - Cheshenko, N, Keller, MJ, MasCasullo, V, Jarvis, GA, Cheng, H, John, M, Li, J-H, Hogarty, K, Anderson, RA, Waller, DP, Zaneveld, LJD, Profy, AT, Klotman, ME, and Herold, BC. "Candidate topical microbicides bind herpes simplex virus glycoprotein B and prevent viral entry and cell-to-cell spread." Antimicrob Agents Chemother 48, no. 6 (June 2004): 2025-2036. Full Text Link to Item
  - Winston, JA, Klotman, PE, and Klotman, M. "Renal Manifestations of HIV Infection." (April 8, 2004): 651-661. (Chapter) Full Text
  - Vargas, J, Gusella, GL, Najfeld, V, Klotman, ME, and Cara, A. "Novel integrase-defective lentiviral episomal vectors for gene transfer." Hum Gene Ther 15, no. 4 (April 2004): 361-372. Full Text Link to Item
  - He, JC, Husain, M, Sunamoto, M, D'Agati, VD, Klotman, ME, Iyengar, R, and Klotman, PE. "Nef stimulates proliferation of glomerular podocytes through activation of Src-dependent Stat3 and MAPK1,2 pathways." Journal of Clinical Investigation 114, no. 5 (2004): 643-651. Full Text
  - Ross, MD, Bruggeman, LA, Hanss, B, Sunamoto, M, Marras, D, Klotman, ME, and Klotman, PE. "Podocan, a novel small leucine-rich repeat protein expressed in the sclerotic glomerular lesion of experimental HIV-associated nephropathy." J Biol Chem 278, no. 35 (August 29, 2003): 33248-33255. Full Text Link to Item
  - Chang, TL-Y, François, F, Mosoian, A, and Klotman, ME. "CAF-mediated human immunodeficiency virus (HIV) type 1 transcriptional inhibition is distinct from alpha-defensin-1 HIV inhibition." J Virol 77, no. 12 (June 2003): 6777-6784. Link to Item
  - Hernandez, PA, Gorlin, RJ, Lukens, JN, Taniuchi, S, Bohinjec, J, Francois, F, Klotman, ME, and Diaz, GA. "Mutations in the chemokine receptor gene CXCR4 are associated with WHIM syndrome, a combined immunodeficiency disease." Nat Genet 34, no. 1 (May 2003): 70-74. Full Text Link to Item
  - Keller, MJ, Klotman, ME, and Herold, BC. "Rigorous pre-clinical evaluation of topical microbicides to prevent transmission of human immunodeficiency virus." J Antimicrob Chemother 51, no. 5 (May 2003): 1099-1102. (Review) Full Text Link to Item
  - Keller, MJ, Klotman, ME, and Herold, BC. "Development of topical microbicides for prevention of human immunodeficiency virus and herpes simplex virus." Am J Reprod Immunol 49, no. 5 (May 2003): 279-284. (Review) Link to Item
  - François, F, and Klotman, ME. "Phosphatidylinositol 3-kinase regulates human immunodeficiency virus type 1 replication following viral entry in primary CD4+ T lymphocytes and macrophages." J Virol 77, no. 4 (February 2003): 2539-2549. Link to Item
  - Herold, BC, Scordi-Bello, I, Cheshenko, N, Marcellino, D, Dzuzelewski, M, Francois, F, Morin, R, Casullo, VM, Anderson, RA, Chany, C, Waller, DP, Zaneveld, LJD, and Klotman, ME. "Mandelic acid condensation polymer: novel candidate microbicide for prevention of human immunodeficiency virus and herpes simplex virus entry." J Virol 76, no. 22 (November 2002): 11236-11244. Link to Item
  - Husain, M, Gusella, GL, Klotman, ME, Gelman, IH, Ross, MD, Schwartz, EJ, Cara, A, and Klotman, PE. "HIV-1 Nef induces proliferation and anchorage-independent growth in podocytes." J Am Soc Nephrol 13, no. 7 (July 2002): 1806-1815. Link to Item
  - Schwartz, EJ, Fierer, DS, Neumann, AU, Keller, MJ, Parkas, V, Zhang, DY, Klotman, ME, Winston, JA, and Klotman, PE. "HIV-1 dynamics in haemodialysis patients." AIDS 16, no. 9 (June 14, 2002): 1301-1303. (Letter) Link to Item
  - Marras, D, Bruggeman, LA, Gao, F, Tanji, N, Mansukhani, MM, Cara, A, Ross, MD, Gusella, GL, Benson, G, D'Agati, VD, Hahn, BH, Klotman, ME, and Klotman, PE. "Replication and compartmentalization of HIV-1 in kidney epithelium of patients with HIV-associated nephropathy." Nat Med 8, no. 5 (May 2002): 522-526. Full Text Link to Item
  - Gusella, GL, Fedorova, E, Hanss, B, Marras, D, Klotman, ME, and Klotman, PE. "Lentiviral gene transduction of kidney." Hum Gene Ther 13, no. 3 (February 10, 2002): 407-414. Full Text Link to Item
  - Cara, A, Vargas, J, Keller, M, Jones, S, Mosoian, A, Gurtman, A, Cohen, A, Parkas, V, Wallach, F, Chusid, E, Gelman, IH, and Klotman, ME. "Circular viral DNA and anomalous junction sequence in PBMC of HIV-infected individuals with no detectable plasma HIV RNA." Virology 292, no. 1 (January 5, 2002): 1-5. Full Text Link to Item
  - Chang, TL-Y, Mosoian, A, Pine, R, Klotman, ME, and Moore, JP. "A soluble factor(s) secreted from CD8(+) T lymphocytes inhibits human immunodeficiency virus type 1 replication through STAT1 activation." J Virol 76, no. 2 (January 2002): 569-581. Link to Item
  - Gusella, GL, Fedorova, E, Marras, D, Klotman, PE, and Klotman, ME. "In vivo gene transfer to kidney by lentiviral vector." Kidney International 61, no. SUPPL. 1 (2002): S32-S36.
  - Gusella, GL, Fedorova, E, Marras, D, Klotman, PE, and Klotman, ME. "In vivo gene transfer to kidney by lentiviral vector." Kidney Int 61, no. 1 Suppl (January 2002): S32-S36. Full Text Link to Item
  - Klotman, P, Roseberg, MM, and Klotman, M. "Editorial comment: Renal insufficiency in HIV-infected patients may not always be HIVAN." AIDS Reader 12, no. 6 (2002): 273--.
  - Stern, AS, Klotman, ME, Ioannou, YA, Burrow, CR, Wilson, PD, Klotman, PE, and Lipkowitz, MS. "Polarity of α-galactosidase A uptake by renal tubule cells." Kidney International 61, no. SUPPL. 1 (2002): S52-S55.
  - Stern, AS, Klotman, ME, Ioannou, YA, Burrow, CR, Wilson, PD, Klotman, PE, and Lipkowitz, MS. "Polarity of alpha-galactosidase A uptake by renal tubule cells." Kidney Int 61, no. 1 Suppl (January 2002): S52-S55. Full Text Link to Item
  - Huprikar, SS, Datta, SD, Lang, L, and Klotman, ME. "Viral load and CD4 count as predictors of response to hepatitis B vaccine." CLINICAL INFECTIOUS DISEASES 33, no. 7 (October 1, 2001): 1153-1153. Link to Item
  - Schecter, AD, Berman, AB, Yi, L, Mosoian, A, McManus, CM, Berman, JW, Klotman, ME, and Taubman, MB. "HIV envelope gp120 activates human arterial smooth muscle cells." Proc Natl Acad Sci U S A 98, no. 18 (August 28, 2001): 10142-10147. Full Text Link to Item
  - Jones, S, and Klotman, ME. "Impact of genotypic resistance testing on physician selection of antiretroviral therapy." J Hum Virol 4, no. 4 (July 2001): 214-216. Link to Item
  - Winston, JA, Bruggeman, LA, Ross, MD, Jacobson, J, Ross, L, D'Agati, VD, Klotman, PE, and Klotman, ME. "Nephropathy and establishment of a renal reservoir of HIV type 1 during primary infection." N Engl J Med 344, no. 26 (June 28, 2001): 1979-1984. Full Text Link to Item
  - Schecter, AD, Berman, AB, Yi, L, Berman, JW, Klotman, ME, and Taubman, MB. "Human immunodeficiency viral envelope protein, gp120, induces tissue factor activity in human arterial smooth muscle cells." ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 21, no. 4 (April 2001): 690-690. Link to Item
  - Gillim, L, Gusella, GL, Vargas, J, Marras, D, Klotman, ME, and Cara, A. "Development of a novel screen for protease inhibitors." Clin Diagn Lab Immunol 8, no. 2 (March 2001): 437-440. Full Text Link to Item
  - Bruggeman, LA, Ross, MD, Tanji, N, Cara, A, Dikman, S, Gordon, RE, Burns, GC, D'Agati, VD, Winston, JA, Klotman, ME, and Klotman, PE. "Renal epithelium is a previously unrecognized site of HIV-1 infection." J Am Soc Nephrol 11, no. 11 (November 2000): 2079-2087. Link to Item
  - Jacobson, JM, Lowy, I, Fletcher, CV, O'Neill, TJ, Tran, DN, Ketas, TJ, Trkola, A, Klotman, ME, Maddon, PJ, Olson, WC, and Israel, RJ. "Single-dose safety, pharmacology, and antiviral activity of the human immunodeficiency virus (HIV) type 1 entry inhibitor PRO 542 in HIV-infected adults." J Infect Dis 182, no. 1 (July 2000): 326-329. Full Text Link to Item
  - Jones, S, and Klotman, ME. "Access to genotypic resistance testing alters physician selection of antiretroviral therapy." CLINICAL INFECTIOUS DISEASES 31, no. 1 (July 2000): 275-275. Link to Item
  - Mosoian, A, Teixeira, A, Caron, E, Piwoz, J, and Klotman, ME. "CD8⁺ cell lines isolated from HIV-1-infected children have potent soluble HIV-1 inhibitory activity that differs from β-chemokines." Viral Immunology 13, no. 4 (2000): 481-495.
  - Mosoian, A, Teixeira, A, Caron, E, Piwoz, J, and Klotman, ME. "CD8+ cell lines isolated from HIV-1-infected children have potent soluble HIV-1 inhibitory activity that differs from beta-chemokines." Viral Immunol 13, no. 4 (2000): 481-495. Full Text Link to Item
  - Tellier, MC, Greco, G, Klotman, M, Mosoian, A, Cara, A, Arap, W, Ruoslahti, E, Pasqualini, R, and Schnapp, LM. "Superfibronectin, a multimeric form of fibronectin, increases HIV infection of primary CD4⁺ T lymphocytes." Journal of Immunology 164, no. 6 (2000): 3236-3245.
  - Lipkowitz, MS, Hanss, B, Tulchin, N, Wilson, PD, Langer, JC, Ross, MD, Kurtzman, GJ, Klotman, PE, and Klotman, ME. "Transduction of renal cells in vitro and in vivo by adeno-associated virus gene therapy vectors." J Am Soc Nephrol 10, no. 9 (September 1999): 1908-1915. Link to Item
  - Winston, JA, Klotman, ME, and Klotman, PE. "HIV-associated nephropathy is a late, not early, manifestation of HIV-1 infection." Kidney Int 55, no. 3 (March 1999): 1036-1040. (Review) Full Text Link to Item
  - Gelfand, JM, Rudikoff, D, Lebwohl, M, and Klotman, ME. "Effect of UV-B phototherapy on plasma HIV type 1 RNA viral level: a self-controlled prospective study." Arch Dermatol 134, no. 8 (August 1998): 940-945. Link to Item
  - Gurtman, A, Borrego, F, and Klotman, ME. "Management of antiretroviral therapy." Semin Nephrol 18, no. 4 (July 1998): 459-480. (Review) Link to Item
  - Langer, JC, Klotman, ME, Hanss, B, Tulchin, N, Bruggeman, LA, Klotman, PE, and Lipkowitz, MS. "Adeno-associated virus gene transfer into renal cells: potential for in vivo gene delivery." Exp Nephrol 6, no. 3 (May 1998): 189-194. (Review) Link to Item
  - Rivadeneira, ED, Popescu, NC, Zimonjic, DB, Cheng, GS, Nelson, PJ, Ross, MD, DiPaolo, JA, and Klotman, ME. "Sites of recombinant adeno-associated virus integration." Int J Oncol 12, no. 4 (April 1998): 805-810. Link to Item
  - Klotman, M. "Potential role for G-protein coupled receptors in HIV-associated nephropathy." Kidney International 54, no. 6 (1998): 2243-2244.
  - Klotman, ME, and Klotman, PE. "Seminars in nephrology." Seminars in Nephrology 18, no. 4 (1998): 371-372.
  - Snoeck, HW, Tao, W, and Klotman, ME. "Adeno-associated viral vectors: background and technical aspects." Exp Nephrol 5, no. 6 (November 1997): 514-520. (Review) Link to Item
  - Cereseto, A, Berneman, Z, Koralnik, I, Vaughn, J, Franchini, G, and Klotman, ME. "Differential expression of alternatively spliced pX mRNAs in HTLV-I-infected cell lines." Leukemia 11, no. 6 (June 1997): 866-870. Link to Item
  - Lipkowitz, MS, Klotman, ME, Bruggeman, LA, Nicklin, P, Hanss, B, Rappaport, J, and Klotman, PE. "Molecular therapy for renal diseases." Am J Kidney Dis 28, no. 4 (October 1996): 475-492. (Review) Link to Item
  - Cereseto, A, Diella, F, Mulloy, JC, Cara, A, Michieli, P, Grassmann, R, Franchini, G, and Klotman, ME. "p53 functional impairment and high p21waf1/cip1 expression in human T-cell lymphotropic/leukemia virus type I-transformed T cells." Blood 88, no. 5 (September 1, 1996): 1551-1560. Link to Item
  - Bruggeman, LA, Thomson, MM, Nelson, PJ, Kopp, JB, Rappaport, J, Klotman, PE, and Klotman, ME. "Patterns of HIV-1 mRNA expression in transgenic mice are tissue-dependent." Virology 202, no. 2 (August 1, 1994): 940-948. Full Text Link to Item
  - Santoro, TJ, Bryant, JL, Pellicoro, J, Klotman, ME, Kopp, JB, Bruggeman, LA, Franks, RR, Notkins, AL, and Klotman, PE. "Growth failure and AIDS-like cachexia syndrome in HIV-1 transgenic mice." Virology 201, no. 1 (May 15, 1994): 147-151. Full Text Link to Item
  - Gallo, RC, and Klotman, ME. "1993 Annual Meeting of the Laboratory of Tumor Cell Biology: Introduction." AIDS Research and Human Retroviruses 10, no. SUPPL. 1 (1994): S1-.
  - Dhawan, S, Weeks, BS, Abbasi, F, Gralnick, HR, Notkins, AL, Klotman, ME, Yamada, KM, and Klotman, PE. "Increased expression of alpha 4 beta 1 and alpha 5 beta 1 integrins on HTLV-I-infected lymphocytes." Virology 197, no. 2 (December 1993): 778-781. Full Text Link to Item
  - Li, G, Lisziewicz, J, Sun, D, Zon, G, Daefler, S, Wong-Staal, F, Gallo, RC, and Klotman, ME. "Inhibition of Rev activity and human immunodeficiency virus type 1 replication by antisense oligodeoxynucleotide phosphorothioate analogs directed against the Rev-responsive element." J Virol 67, no. 11 (November 1993): 6882-6888. Link to Item
  - Weeks, BS, Klotman, ME, Holloway, E, Stetler-Stevenson, WG, Kleinman, HK, and Klotman, PE. "HIV-1 infection stimulates T cell invasiveness and synthesis of the 92-kDa type IV collagenase." AIDS Res Hum Retroviruses 9, no. 6 (June 1993): 513-518. Full Text Link to Item
  - Weeks, BS, Desai, K, Loewenstein, PM, Klotman, ME, Klotman, PE, Green, M, and Kleinman, HK. "Identification of a novel cell attachment domain in the HIV-1 Tat protein and its 90-kDa cell surface binding protein." J Biol Chem 268, no. 7 (March 5, 1993): 5279-5284. Link to Item
  - Koralnik, IJ, Gessain, A, Klotman, ME, Lo Monico, A, Berneman, ZN, and Franchini, G. "Protein isoforms encoded by the pX region of human T-cell leukemia/lymphotropic virus type I." Proc Natl Acad Sci U S A 89, no. 18 (September 15, 1992): 8813-8817. Link to Item
  - Perfect, JR, Klotman, ME, Gilbert, CC, Crawford, DD, Rosner, GL, Wright, KA, and Peters, WP. "Prophylactic intravenous amphotericin B in neutropenic autologous bone marrow transplant recipients." J Infect Dis 165, no. 5 (May 1992): 891-897. Link to Item
  - Berneman, ZN, Gartenhaus, RB, Reitz, MS, Blattner, WA, Manns, A, Hanchard, B, Ikehara, O, Gallo, RC, and Klotman, ME. "Expression of alternatively spliced human T-lymphotropic virus type I pX mRNA in infected cell lines and in primary uncultured cells from patients with adult T-cell leukemia/lymphoma and healthy carriers." Proc Natl Acad Sci U S A 89, no. 7 (April 1, 1992): 3005-3009. Link to Item
  - Kopp, JB, Klotman, ME, Adler, SH, Bruggeman, LA, Dickie, P, Marinos, NJ, Eckhaus, M, Bryant, JL, Notkins, AL, and Klotman, PE. "Progressive glomerulosclerosis and enhanced renal accumulation of basement membrane components in mice transgenic for human immunodeficiency virus type 1 genes." Proc Natl Acad Sci U S A 89, no. 5 (March 1, 1992): 1577-1581. Link to Item
  - Klotman, ME, Kim, SY, Buchbinder, A, DeRossi, A, Baltimore, D, and Wong-Staal, F. "Kinetics of expression of multiply spliced RNA in early human immunodeficiency virus type 1 infection of lymphocytes and monocytes." Proc Natl Acad Sci U S A 89, no. 3 (February 1, 1992): 1148-. Link to Item
  - Berneman, ZN, Gartenhaus, RB, Reitz, MS, Klotman, ME, and Gallo, RC. "cDNA sequencing confirms HTLV-I expression in adult T-cell leukemia/lymphoma and different sequence variations in vivo and in vitro." Leukemia 6 Suppl 3 (1992): 67S-71S. Link to Item
  - Klotman, ME, Kim, S, Buchbinder, A, DeRossi, A, Baltimore, D, and Wong-Staal, F. "Erratum: Kinetics of expression of multiply spliced RNA in early human immunodeficiency virus type 1 infection of lymphocytes and monocytes (Proc. Natl. Acad. Sci. USA (June 1991) 88 (5011-5015))." Proceedings of the National Academy of Sciences of the United States of America 89, no. 3 (1992): 1148--.
  - Lisziewicz, J, Sun, D, Klotman, M, Agrawal, S, Zamecnik, P, and Gallo, R. "Specific inhibition of human immunodeficiency virus type 1 replication by antisense oligonucleotides: An in vitro model for treatment." Proceedings of the National Academy of Sciences of the United States of America 89, no. 23 (1992): 11209-11213. Full Text
  - Gartenhaus, RB, Wong-Staal, F, and Klotman, ME. "The promoter of human T-cell leukemia virus type-I is repressed by the immediate-early gene region of human cytomegalovirus in primary blood lymphocytes." Blood 78, no. 11 (December 1, 1991): 2956-2961. Link to Item
  - Weeks, BS, Klotman, ME, Dhawan, S, Kibbey, M, Rappaport, J, Kleinman, HK, Yamada, KM, and Klotman, PE. "HIV-1 infection of human T lymphocytes results in enhanced alpha 5 beta 1 integrin expression." J Cell Biol 114, no. 4 (August 1991): 847-853. Link to Item
  - Klotman, ME, Kim, S, Buchbinder, A, DeRossi, A, Baltimore, D, and Wong-Staal, F. "Kinetics of expression of multiply spliced RNA in early human immunodeficiency virus type 1 infection of lymphocytes and monocytes." Proc Natl Acad Sci U S A 88, no. 11 (June 1, 1991): 5011-5015. Link to Item
  - Daefler, S, Klotman, ME, and Wong-Staal, F. "Trans-activating rev protein of the human immunodeficiency virus 1 interacts directly and specifically with its target RNA." Proc Natl Acad Sci U S A 87, no. 12 (June 1990): 4571-4575. Link to Item
  - Shaunak, S, Albright, RE, Klotman, ME, Henry, SC, Bartlett, JA, and Hamilton, JD. "Amplification of HIV-1 provirus from cerebrospinal fluid and its correlation with neurologic disease." J Infect Dis 161, no. 6 (June 1990): 1068-1072. Link to Item
  - Sadaie, MR, Tschachler, E, Valerie, K, Rosenberg, M, Felber, BK, Pavlakis, GN, Klotman, ME, and Wong-Staal, F. "Activation of tat-defective human immunodeficiency virus by ultraviolet light." New Biol 2, no. 5 (May 1990): 479-486. Link to Item
  - Klotman, ME, Henry, SC, Greene, RC, Brazy, PC, Klotman, PE, and Hamilton, JD. "Detection of mouse cytomegalovirus nucleic acid in latently infected mice by in vitro enzymatic amplification." J Infect Dis 161, no. 2 (February 1990): 220-225. Link to Item
  - Kim, JH, Cooper, RA, Welty-Wolf, KE, Harrell, LJ, Zwadyk, P, and Klotman, ME. "Pseudomonas putrefaciens bacteremia." Rev Infect Dis 11, no. 1 (January 1989): 97-104. Link to Item
  - Peters, WP, Stuart, A, Klotman, M, Gilbert, C, Jones, RB, Shpall, EJ, Gockerman, J, Bast, RC, and Moore, JO. "High-dose combination cyclophosphamide, cisplatin, and melphalan with autologous bone marrow support. A clinical and pharmacologic study." Cancer Chemother Pharmacol 23, no. 6 (1989): 377-383. Link to Item
  - Schmader, KE, van der Horst, CM, and Klotman, ME. "Epstein-Barr virus and the elderly host." Rev Infect Dis 11, no. 1 (January 1989): 64-73. (Review) Link to Item
  - Buchbinder, A, Josephs, SF, Ablashi, D, Salahuddin, SZ, Klotman, ME, Manak, M, Krueger, GR, Wong-Staal, F, and Gallo, RC. "Polymerase chain reaction amplification and in situ hybridization for the detection of human B-lymphotropic virus." J Virol Methods 21, no. 1-4 (September 1988): 191-197. Link to Item
  - Klotman, ME, Henry, SC, and Hamilton, JD. "Determinants of the source of cytomegalovirus in murine renal allograft recipients." Transplantation 44, no. 5 (November 1987): 636-639. Link to Item
  - Klotman, ME, and Hamilton, JD. "Cytomegalovirus pneumonia." Semin Respir Infect 2, no. 2 (June 1987): 95-103. (Review) Link to Item
  - Klotman, ME, Starnes, D, and Hamilton, JD. "The source of murine cytomegalovirus in mice receiving kidney allografts." J Infect Dis 152, no. 6 (December 1985): 1192-1196. Link to Item
  - Klotman, ME. "Laboratory detection of urinary tract infections." Kidney 18, no. 1 (1985): 1-4.
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