Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Fellow in Infectious Diseases, Medicine, Duke University 1983 - 1985
  • Resident, Medicine, Duke University 1980 - 1983
  • M.D., Duke University 1980
• 

  Duke Appointment History

  • Chair, Department of Medicine, Medicine, Clinical Science Departments 2010 - 2017
  • Consulting Associate in the Department of Medicine, Medicine, Infectious Diseases, Medicine 2010
  • Assistant Professor, Medicine, Clinical Science Departments 1986 - 1990
  • Associate, Medicine, Clinical Science Departments 1985 - 1986
• Recognition
• 

  In the News

  • MAR 5, 2018

    Viewpoints podcast

    Why is it Important to Explore the Early-life Origins of Health and Disease?

  • JAN 19, 2018

    Viewpoint podcast

    Dean Mary Klotman on Translating Duke Health

  • NOV 2, 2017

    School of Medicine Viewpoint Podcast

    Mary Klotman: What Did it Take to Change HIV From a Fatal Diagnosis to an Often-manageable, Disease?

  • OCT 10, 2017

    School of Medicine Viewpoint

    Mary Klotman: What is Data Science and Why Is It Important?

  • AUG 29, 2017

    Dr. Mary Klotman: Why Diversity Is Necessary in Academic Medicine

  • JUL 11, 2017

    From Undergraduate to Dean: Dr. Mary Klotman Describes What She Has Learned at Duke

  • MAY 25, 2017

    School of Medicine

    Duke Hosts Precision Medicine World Conference

  • APR 24, 2017

    Duke School of Medicine

    Klotman Joins Roundtable Discussion with Rep. David Price to Discuss NIH Budget

  • JAN 30, 2017

    Dr. Mary Klotman Named Dean of Duke School of Medicine

  • APR 6, 2015

    The News & Observer

    Duke HIV researchers receive large federal grants

  • APR 5, 2015

    Duke Research Teams Win Large Federal Grants for HIV Vaccine Studies

  • OCT 21, 2014

    Klotman, chair of Medicine, Named to Institute of Medicine
• 

  Awards & Honors

  • Member. Institute of Medicine of The National Academies. 2014
  • Membership. National Academy of Medicine. 2014
• Expertise
• 

  Subject Headings

  • Acquired Immunodeficiency Syndrome
  • Antibodies, Viral
  • Antiretroviral Therapy, Highly Active
  • Drug Carriers
  • Education, Medical
  • Enzyme-Linked Immunospot Assay
  • HIV
  • HIV Infections
  • Health
  • Integrase Inhibitors
  • Kidney
  • Leadership
  • Science
  • Vaccines, Synthetic
• Research
• 

  Selected Grants

  • Persistent HIV Infection in the Kidney awarded by Baylor College of Medicine 1999 - 2022
  • Mentoring Patient Oriented Research in Antibiotic-Resistant Bacteria awarded by National Institutes of Health 2011 - 2021
  • Interdisciplinary Research Training Program in AIDS awarded by National Institutes of Health 2010 - 2020
  • The Genitourinary Tract as a compartment and reservoir for HIV awarded by National Institutes of Health 2015 - 2020
  • Integrase Defective Lentiviral Vector (IDLV) for HIV Vaccine Development awarded by National Institutes of Health 2015 - 2020
  • Viral Oncology Training Grant awarded by National Institutes of Health 1980 - 2019
  • Systems Biology Approaches for Predicting Cardiometabolic Risk in Persons Living with HIV awarded by National Institutes of Health 2015 - 2018
  • Serial Block Face Scanning Electron Microscope awarded by National Institutes of Health 2016 - 2018
  • Impact of polyploidy on establishing an HIV-1 reservoir in the kidney awarded by University of Alabama at Birmingham 2014 - 2017
  • The Pathogenesis of HIV-Associated Nephropathy awarded by Baylor College of Medicine 2011 - 2016
• Publications & Artistic Works
• 

  Selected Publications

  • Conference Papers

    • Swanepoel, CR, Atta, MG, D'Agati, VD, Estrella, MM, Fogo, AB, Naicker, S, Post, FA, Wearne, N, Winkler, CA, Cheung, M, Wheeler, DC, Winkelmayer, WC, Wyatt, CM, Abu-Alfa, A, Adu, D, Agodoa, LY, Alpers, CE, Arogundade, FA, Ashuntantang, G, Bagnis, CI, Bhimma, R, Brocheriou, I, Cohen, AH, Cohen, K, Cook, HT, de Seigneux, S, Fabian, J, Finkelstein, FO, Haas, M, Hamzah, L, Hendry, BM, Imonje, V, Jennette, JC, Kimmel, PL, Klotman, ME, Klotman, PE, Larsen, CP, McCulloch, MI, Mosiane, P, and Nast, CC et al. "Kidney disease in the setting of HIV infection: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference." March 1, 2018.  Full Text
    • Blasi, M, Negri, D, Santra, S, Parks, R, Shen, X, Tomaras, G, Permar, S, Montefiori, D, LaBranche, C, Ferrari, G, Alam, M, Liao, H, Moody, AM, Haynes, BF, Klotman, ME, and Cara, A. "A Single Immunization with Integrase Defective Lentiviral Vector Expressing gp140 Induces Persistent and Functional Immune Response in Rhesus Monkeys." November 1, 2013.  Link to Item
    • Tuyama, AC, Hong, F, Schecter, AD, Mosoian, A, Chen, BK, Chen, P, Klotman, ME, and Bansal, MB. "HIV entry and replication stellate cells promotes cellular activation and fibrogenesis: Implications for hepatic fibrosis in HIV/HCV co-infection." October 2007.  Link to Item
    • Zerhouni-Layachi, B, Marras, D, Francois, F, Klotman, PE, and Klotman, ME. "Phenotypic characterization of HIV-1 envelopes derived from patients with HIVAN." November 2003.  Link to Item
    • Cara, A, Vargas, J, Keller, M, Jones, S, Mosoian, A, Gurtman, A, Cohen, A, Parkas, V, Wallach, F, Chusid, E, Gelman, IH, and Klotman, ME. "Circular viral DNA and anomalous junction sequence in PBMC of HIV-infected individuals with no detectable plasma HIV RNA." January 5, 2002.  Full Text  Link to Item

  • Journal Articles

    • Payne, EH, Ramalingam, D, Fox, DT, and Klotman, ME. "Polyploidy and Mitotic Cell Death Are Two Distinct HIV-1 Vpr-Driven Outcomes in Renal Tubule Epithelial Cells." Journal of virology 92, no. 2 (January 2018).  Full Text
    • Negri, D, Blasi, M, LaBranche, C, Parks, R, Balachandran, H, Lifton, M, Shen, X, Denny, T, Ferrari, G, Vescio, MF, Andersen, H, Montefiori, DC, Tomaras, GD, Liao, H-X, Santra, S, Haynes, BF, Klotman, ME, and Cara, A. "Immunization with an SIV-based IDLV Expressing HIV-1 Env 1086 Clade C Elicits Durable Humoral and Cellular Responses in Rhesus Macaques." Molecular therapy : the journal of the American Society of Gene Therapy 24, no. 11 (November 2016): 2021-2032.  Full Text  Open Access Copy
    • Chen, P, Yi, Z, Zhang, W, Klotman, ME, and Chen, BK. "HIV infection-induced transcriptional program in renal tubular epithelial cells activates a CXCR2-driven CD4+ T-cell chemotactic response." AIDS (London, England) 30, no. 12 (July 2016): 1877-1888.  Full Text
    • Blasi, M, Carpenter, JH, Balakumaran, B, Cara, A, Gao, F, and Klotman, ME. "Identification of HIV-1 genitourinary tract compartmentalization by analyzing the env gene sequences in urine." AIDS (London, England) 29, no. 13 (August 2015): 1651-1657.  Full Text
    • Michelini, Z, Negri, D, Biava, M, Baroncelli, S, Spada, M, Leone, P, Bona, R, Blasi, M, Nègre, D, Klotman, ME, and Cara, A. "Murine granulocyte-macrophage colony-stimulating factor expressed from a bicistronic simian immunodeficiency virus-based integrase-defective lentiviral vector does not enhance T-cell responses in mice." Viral immunology 27, no. 10 (December 2014): 512-520.  Full Text
    • Carethers, JM, Coughlin, S, Diamond, B, Erzurum, S, Fried, LP, Jameson, JL, Kaushansky, K, Klotman, ME, Lemon, S, Mitchell, B, Rothman, P, Sawyers, C, Seidman, C, and Somlo, S. "The imperative to invest in science has never been greater." The Journal of clinical investigation 124, no. 11 (November 2014): 5085-.  Full Text
    • Blasi, M, Balakumaran, B, Chen, P, Negri, DRM, Cara, A, Chen, BK, and Klotman, ME. "Renal epithelial cells produce and spread HIV-1 via T-cell contact." AIDS (London, England) 28, no. 16 (October 2014): 2345-2353.  Full Text
    • Carethers, JM, Coughlin, S, Diamond, B, Erzurum, S, Fried, LP, Jameson, JL, Kaushansky, K, Klotman, ME, Lemon, S, Mitchell, B, Rothman, P, Sawyers, C, Seidman, C, and Somlo, S. "The imperative to invest in science has never been greater." Journal of Clinical Investigation 124, no. 9 (September 2, 2014): 3680-3681.  Full Text
    • Blasi, M, Balakumaran, B, Chen, P, Negri, DRM, Cara, A, Chen, BK, and Klotman, ME. "Renal epithelial cells produce and spread HIV-1 via T-cell contact." AIDS 28, no. 16 (January 1, 2014): 2345-2353.  Full Text
    • Rossi, A, Michelini, Z, Leone, P, Borghi, M, Blasi, M, Bona, R, Spada, M, Grasso, F, Gugliotta, A, Klotman, ME, Cara, A, and Negri, D. "Optimization of mucosal responses after intramuscular immunization with integrase defective lentiviral vector." PloS one 9, no. 9 (January 2014): e107377-.  Full Text
    • Micsenyi, AM, Zony, C, Alvarez, RA, Durham, ND, Chen, BK, and Klotman, ME. "Postintegration HIV-1 infection of cervical epithelial cells mediates contact-dependent productive infection of T cells." J Infect Dis 208, no. 11 (December 1, 2013): 1756-1767.  Full Text  Link to Item
    • Hutter, R, Huang, L, Speidl, WS, Giannarelli, C, Trubin, P, Bauriedel, G, Klotman, ME, Fuster, V, Badimon, JJ, and Klotman, PE. "Novel small leucine-rich repeat protein podocan is a negative regulator of migration and proliferation of smooth muscle cells, modulates neointima formation, and is expressed in human atheroma." Circulation 128, no. 22 (November 26, 2013): 2351-2363.  Full Text
    • Hutter, R, Huang, L, Speidl, WS, Giannarelli, C, Trubin, P, Bauriedel, G, Klotman, ME, Fuster, V, Badimon, JJ, and Klotman, PE. "Novel small leucine-rich repeat protein podocan is a negative regulator of migration and proliferation of smooth muscle cells, modulates neointima formation, and is expressed in human atheroma." Circulation 128, no. 22 (November 26, 2013): 2351-2363.  Full Text  Link to Item
    • Todd, RF, Salata, RA, Klotman, ME, Weisfeldt, ML, Katz, JT, Xian, SX, Hearn, DP, and Lipner, RS. "Career outcomes of the graduates of the American Board of Internal Medicine Research Pathway, 1995-2007." Acad Med 88, no. 11 (November 2013): 1747-1753.  Full Text  Link to Item
    • Todd, RF, Salata, RA, Klotman, ME, Weisfeldt, ML, Katz, JT, Xian, SX, Hearn, DP, and Lipner, RS. "Career outcomes of the graduates of the American board of internal medicine research pathway, 1995-2007." Academic Medicine 88, no. 11 (January 1, 2013): 1747-1753.  Full Text
    • Blasi, M, Rossi, A, Michelini, Z, Leone, P, Perretta, G, Cimarelli, A, Klotman, ME, Negri, D, and Cara, A. "Simian immunodeficiency virus-Vpx as an adjuvant for integrase defective lentiviral vector-based vaccines." RETROVIROLOGY 9 (September 13, 2012).  Full Text  Link to Item
    • Negri, DRM, Rossi, A, Blasi, M, Michelini, Z, Leone, P, Chiantore, MV, Baroncelli, S, Perretta, G, Cimarelli, A, Klotman, ME, and Cara, A. "Simian immunodeficiency virus-Vpx for improving integrase defective lentiviral vector-based vaccines. (Published online)" Retrovirology 9 (August 22, 2012): 69-.  Full Text  Link to Item
    • Papeta, N, Kiryluk, K, Patel, A, Sterken, R, Kacak, N, Snyder, HJ, Imus, PH, Mhatre, AN, Lawani, AK, Julian, BA, Wyatt, RJ, Novak, J, Wyatt, CM, Ross, MJ, Winston, JA, Klotman, ME, Cohen, DJ, Appel, GB, D'Agati, VD, Klotman, PE, and Gharavi, AG. "APOL1 variants increase risk for FSGS and HIVAN but not IgA nephropathy." J Am Soc Nephrol 22, no. 11 (November 2011): 1991-1996.  Full Text  Link to Item
    • Chen, P, Chen, BK, Mosoian, A, Hays, T, Ross, MJ, Klotman, PE, and Klotman, ME. "Virological synapses allow HIV-1 uptake and gene expression in renal tubular epithelial cells." J Am Soc Nephrol 22, no. 3 (March 2011): 496-507.  Full Text  Link to Item
    • Ding, J, Rapista, A, Teleshova, N, Lu, W, Klotman, ME, and Chang, TL. "Mucosal human defensins 5 and 6 antagonize the anti-HIV activity of candidate polyanion microbicides." J Innate Immun 3, no. 2 (2011): 208-212.  Full Text  Link to Item
    • Jao, J, Palmer, D, Leus, I, Tih, P, Baweja, M, Klotman, M, Sperling, R, and Wyatt, C. "Prevalence and predictors of proteinuria in HIV-infected and uninfected pregnant women in Cameroon." Nephrology Dialysis Transplantation 26, no. 9 (2011): 3051-3053.  Full Text
    • Negri, DRM, Bona, R, Michelini, Z, Leone, P, Macchia, I, Klotman, ME, Salvatore, M, and Cara, A. "Transduction of human antigen-presenting cells with integrase-defective lentiviral vector enables functional expansion of primed antigen-specific CD8(+) T cells." Hum Gene Ther 21, no. 8 (August 2010): 1029-1035.  Full Text  Link to Item
    • Tuyama, AC, Hong, F, Saiman, Y, Wang, C, Ozkok, D, Mosoian, A, Chen, P, Chen, BK, Klotman, ME, and Bansal, MB. "Human immunodeficiency virus (HIV)-1 infects human hepatic stellate cells and promotes collagen I and monocyte chemoattractant protein-1 expression: implications for the pathogenesis of HIV/hepatitis C virus-induced liver fibrosis." Hepatology 52, no. 2 (August 2010): 612-622.  Full Text  Link to Item
    • Mosoian, A, Teixeira, A, Burns, CS, Sander, LE, Gusella, GL, He, C, Blander, JM, Klotman, P, and Klotman, ME. "Prothymosin-alpha inhibits HIV-1 via Toll-like receptor 4-mediated type I interferon induction." Proc Natl Acad Sci U S A 107, no. 22 (June 1, 2010): 10178-10183.  Full Text  Link to Item
    • Snyder, A, Alsauskas, ZC, Leventhal, JS, Rosenstiel, PE, Gong, P, Chan, JJK, Barley, K, He, JC, Klotman, ME, Ross, MJ, and Klotman, PE. "HIV-1 viral protein r induces ERK and caspase-8-dependent apoptosis in renal tubular epithelial cells." AIDS 24, no. 8 (May 15, 2010): 1107-1119.  Full Text  Link to Item
    • Ding, J, Rapista, A, Teleshova, N, Mosoyan, G, Jarvis, GA, Klotman, ME, and Chang, TL. "Neisseria gonorrhoeae enhances HIV-1 infection of primary resting CD4+ T cells through TLR2 activation." J Immunol 184, no. 6 (March 15, 2010): 2814-2824.  Full Text  Link to Item
    • Chang, TL, and Klotman, M. "Defensins and HIV infection." Soluble Factors Mediating Innate Immune Responses to HIV Infection (2010): 51-63.  Full Text
    • Negri, DRM, Michelini, Z, Baroncelli, S, Spada, M, Vendetti, S, Bona, R, Leone, P, Klotman, ME, and Cara, A. "Nonintegrating Lentiviral Vector-Based Vaccine Efficiently Induces Functional and Persistent CD8+ T Cell Responses in Mice." J Biomed Biotechnol 2010 (2010): 534501-.  Full Text  Link to Item
    • Snyder, A, Alsauskas, Z, Gong, P, Rosenstiel, PE, Klotman, ME, Klotman, PE, and Ross, MJ. "FAT10: a novel mediator of Vpr-induced apoptosis in human immunodeficiency virus-associated nephropathy." J Virol 83, no. 22 (November 2009): 11983-11988.  Full Text  Link to Item
    • Factor, SH, and Klotman, ME. "Zoonotic infections: an emerging threat to human health." Mt Sinai J Med 76, no. 5 (October 2009): 419-420.  Full Text  Link to Item
    • Rosenstiel, PE, Chan, J, Snyder, A, Planelles, V, D'Agati, VD, Klotman, PE, and Klotman, ME. "HIV-1 Vpr activates the DNA damage response in renal tubule epithelial cells." AIDS 23, no. 15 (September 24, 2009): 2054-2056.  Full Text  Link to Item
    • Chen, W-H, Janout, V, Kondo, M, Mosoian, A, Mosoyan, G, Petrov, RR, Klotman, ME, and Regen, SL. "A fine line between molecular umbrella transport and ionophoric activity." Bioconjug Chem 20, no. 9 (September 2009): 1711-1715.  Full Text  Link to Item
    • Michelini, Z, Negri, DRM, Baroncelli, S, Spada, M, Leone, P, Bona, R, Klotman, ME, and Cara, A. "Development and use of SIV-based Integrase defective lentiviral vector for immunization." Vaccine 27, no. 34 (July 23, 2009): 4622-4629.  Full Text  Link to Item
    • Sachdev, DD, Zerhouni-Layachi, B, Ortigoza, M, Profy, AT, Tuen, M, Hioe, CE, and Klotman, ME. "The differential binding and activity of PRO 2000 against diverse HIV-1 envelopes." J Acquir Immune Defic Syndr 51, no. 2 (June 1, 2009): 125-129.  Full Text  Link to Item
    • Wyatt, CM, Morgello, S, Katz-Malamed, R, Wei, C, Klotman, ME, Klotman, PE, and D'Agati, VD. "The spectrum of kidney disease in patients with AIDS in the era of antiretroviral therapy." Kidney Int 75, no. 4 (February 2009): 428-434.  Full Text  Link to Item
    • Abbadessa, G, Accolla, R, Aiuti, F, Albini, A, Aldovini, A, Alfano, M, Antonelli, G, Bartholomew, C, Bentwich, Z, Bertazzoni, U, Berzofsky, JA, Biberfeld, P, Boeri, E, Buonaguro, L, Buonaguro, FM, Bukrinsky, M, Burny, A, Caruso, A, Cassol, S, Chandra, P, Ceccherini-Nelli, L, Chieco-Bianchi, L, Clerici, M, Colombini-Hatch, S, de Giuli Morghen, C, de Maria, A, de Rossi, A, Dierich, M, Della-Favera, R, Dolei, A, Douek, D, Erfle, V, Felber, B, Fiorentini, S, Franchini, G, Gershoni, JM, and Gotch, F et al. "Unsung hero Robert C. Gallo." Science 323, no. 5911 (January 9, 2009): 206-207. (Letter)  Full Text  Link to Item
    • Feng, X, Lu, T-C, Chuang, PY, Fang, W, Ratnam, K, Xiong, H, Ouyang, X, Shen, Y, Levy, DE, Hyink, D, Klotman, M, D'Agati, V, Iyengar, R, Klotman, PE, and He, JC. "Reduction of Stat3 activity attenuates HIV-induced kidney injury." Journal of the American Society of Nephrology 20, no. 10 (2009): 2138-2146.  Full Text
    • Vargas, J, Klotman, ME, and Cara, A. "Conditionally replicating lentiviral-hybrid episomal vectors for suicide gene therapy." Antiviral Res 80, no. 3 (December 2008): 288-294.  Full Text  Link to Item
    • Rosenstiel, PE, Gruosso, T, Letourneau, AM, Chan, JJ, LeBlanc, A, Husain, M, Najfeld, V, Planelles, V, D'Agati, VD, Klotman, ME, and Klotman, PE. "HIV-1 Vpr inhibits cytokinesis in human proximal tubule cells." Kidney Int 74, no. 8 (October 2008): 1049-1058.  Full Text  Link to Item
    • Klotman, ME, Rapista, A, Teleshova, N, Micsenyi, A, Jarvis, GA, Lu, W, Porter, E, and Chang, TL. "Neisseria gonorrhoeae-induced human defensins 5 and 6 increase HIV infectivity: role in enhanced transmission." J Immunol 180, no. 9 (May 1, 2008): 6176-6185.  Link to Item
    • Teleshova, N, Chang, T, Profy, A, and Klotman, ME. "Inhibitory effect of PRO 2000, a candidate microbicide, on dendritic cell-mediated human immunodeficiency virus transfer." Antimicrob Agents Chemother 52, no. 5 (May 2008): 1751-1758.  Full Text  Link to Item
    • Eugenin, EA, Morgello, S, Klotman, ME, Mosoian, A, Lento, PA, Berman, JW, and Schecter, AD. "Human immunodeficiency virus (HIV) infects human arterial smooth muscle cells in vivo and in vitro: implications for the pathogenesis of HIV-mediated vascular disease." Am J Pathol 172, no. 4 (April 2008): 1100-1111.  Full Text  Link to Item
    • Radbill, BD, Wyatt, CM, Vassalotti, JA, Klotman, ME, and Klotman, PE. "Hepatitis B- and HIV-Related Renal Diseases." Therapy in Nephrology & Hypertension (2008): 272-280.  Full Text
    • Chang, TL, Teleshova, N, Rapista, A, Paluch, M, Anderson, RA, Waller, DP, Zaneveld, LJD, Granelli-Piperno, A, and Klotman, ME. "SAMMA, a mandelic acid condensation polymer, inhibits dendritic cell-mediated HIV transmission." FEBS Lett 581, no. 24 (October 2, 2007): 4596-4602.  Full Text  Link to Item
    • Wyatt, CM, Winston, JA, Malvestutto, CD, Fishbein, DA, Barash, I, Cohen, AJ, Klotman, ME, and Klotman, PE. "Chronic kidney disease in HIV infection: an urban epidemic." AIDS 21, no. 15 (October 1, 2007): 2101-2103.  Full Text  Link to Item
    • Salvatore, M, Garcia-Sastre, A, Ruchala, P, Lehrer, RI, Chang, T, and Klotman, ME. "alpha-Defensin inhibits influenza virus replication by cell-mediated mechanism(s)." J Infect Dis 196, no. 6 (September 15, 2007): 835-843.  Full Text  Link to Item
    • Negri, DRM, Michelini, Z, Baroncelli, S, Spada, M, Vendetti, S, Buffa, V, Bona, R, Leone, P, Klotman, ME, and Cara, A. "Successful immunization with a single injection of non-integrating lentiviral vector." Mol Ther 15, no. 9 (September 2007): 1716-1723.  Full Text  Link to Item
    • Negri, DRM, Michelini, Z, Baroncelli, S, Spada, M, Vendetti, S, Buffa, V, Bona, R, Leone, P, Klotman, ME, and Cara, A. "Successful immunization with a single injection of non-integrating lentiviral vector." MOLECULAR THERAPY 15, no. 9 (September 2007): 1716-1723.  Full Text  Link to Item
    • Kaufman, L, Yang, G, Hayashi, K, Ashby, JR, Huang, L, Ross, MJ, Klotman, ME, and Klotman, PE. "The homophilic adhesion molecule sidekick-1 contributes to augmented podocyte aggregation in HIV-associated nephropathy." FASEB J 21, no. 7 (May 2007): 1367-1375.  Full Text  Link to Item
    • Bhadelia, N, Klotman, M, and Caplivski, D. "The HIV-Positive Traveler." American Journal of Medicine 120, no. 7 (2007): 574-580.  Full Text
    • Mosoian, A, Teixeira, A, Burns, CS, Khitrov, G, Zhang, W, Gusella, L, Klotman, P, and Klotman, M. "Influence of prothymosin-α on HIV-1 target cells." Annals of the New York Academy of Sciences 1112 (2007): 269-285.  Full Text
    • Cara, A, and Klotman, ME. "Retroviral E-DNA: persistence and gene expression in nondividing immune cells." J Leukoc Biol 80, no. 5 (November 2006): 1013-1017. (Review)  Full Text  Link to Item
    • Liu, X, Mosoian, A, Li-Yun Chang, T, Zerhouni-Layachi, B, Snyder, A, Jarvis, GA, and Klotman, ME. "Gonococcal lipooligosaccharide suppresses HIV infection in human primary macrophages through induction of innate immunity." J Infect Dis 194, no. 6 (September 15, 2006): 751-759.  Full Text  Link to Item
    • Tuyama, ACG, Cheshenko, N, Carlucci, MJ, Li, J-H, Goldberg, CL, Waller, DP, Anderson, RA, Profy, AT, Klotman, ME, Keller, MJ, and Herold, BC. "ACIDFORM inactivates herpes simplex virus and prevents genital herpes in a mouse model: optimal candidate for microbicide combinations." J Infect Dis 194, no. 6 (September 15, 2006): 795-803.  Full Text  Link to Item
    • Klotman, ME, and Chang, TL. "Defensins in innate antiviral immunity." Nat Rev Immunol 6, no. 6 (June 2006): 447-456. (Review)  Full Text  Link to Item
    • Ross, MJ, Fan, C, Ross, MD, Chu, T-H, Shi, Y, Kaufman, L, Zhang, W, Klotman, ME, and Klotman, PE. "HIV-1 infection initiates an inflammatory cascade in human renal tubular epithelial cells." J Acquir Immune Defic Syndr 42, no. 1 (May 2006): 1-11.  Full Text  Link to Item
    • Ross, MJ, Wosnitzer, MS, Ross, MD, Granelli, B, Gusella, GL, Husain, M, Kaufman, L, Vasievich, M, D'Agati, VD, Wilson, PD, Klotman, ME, and Klotman, PE. "Role of ubiquitin-like protein FAT10 in epithelial apoptosis in renal disease." J Am Soc Nephrol 17, no. 4 (April 2006): 996-1004.  Full Text  Link to Item
    • Dhawan, D, Keller, M, and Klotman, ME. "Topical microbicides: the time has come." AIDS Read 16, no. 3 (March 2006): 144-161. (Review)  Link to Item
    • Fierer, DS, and Klotman, ME. "Kidney and central nervous system as reservoirs of HIV infection." Curr Opin HIV AIDS 1, no. 2 (March 2006): 115-120.  Full Text  Link to Item
    • Wyatt, CM, Arons, RR, Klotman, PE, and Klotman, ME. "Acute renal failure in hospitalized patients with HIV: risk factors and impact on in-hospital mortality." AIDS 20, no. 4 (February 28, 2006): 561-565.  Full Text  Link to Item
    • Zerhouni-Layachi, B, Husain, M, Ross, MJ, Marras, D, Sunamoto, M, Liu, X, Klotman, PE, and Klotman, ME. "Dual tropism of HIV-1 envelopes derived from renal tubular epithelial cells of patients with HIV-associated nephropathy." AIDS 20, no. 4 (February 28, 2006): 621-624.  Full Text  Link to Item
    • Keller, MJ, Zerhouni-Layachi, B, Cheshenko, N, John, M, Hogarty, K, Kasowitz, A, Goldberg, CL, Wallenstein, S, Profy, AT, Klotman, ME, and Herold, BC. "PRO 2000 gel inhibits HIV and herpes simplex virus infection following vaginal application: a double-blind placebo-controlled trial." J Infect Dis 193, no. 1 (January 1, 2006): 27-35.  Full Text  Link to Item
    • Mosoian, A, Teixeira, A, High, AA, Christian, RE, Hunt, DF, Shabanowitz, J, Liu, X, and Klotman, M. "Novel function of prothymosin alpha as a potent inhibitor of human immunodeficiency virus type 1 gene expression in primary macrophages." Journal of Virology 80, no. 18 (2006): 9200-9206.  Full Text
    • Husain, M, D'Agati, VD, He, JC, Klotman, ME, and Klotman, PE. "HIV-1 Nef induces dedifferentiation of podocytes in vivo: a characteristic feature of HIVAN." AIDS 19, no. 17 (November 18, 2005): 1975-1980.  Link to Item
    • John, M, Keller, MJ, Fam, EH, Cheshenko, N, Hogarty, K, Kasowitz, A, Wallenstein, S, Carlucci, MJ, Tuyama, AC, Lu, W, Klotman, ME, Lehrer, RI, and Herold, BC. "Cervicovaginal secretions contribute to innate resistance to herpes simplex virus infection." J Infect Dis 192, no. 10 (November 15, 2005): 1731-1740.  Full Text  Link to Item
    • Scordi-Bello, IA, Mosoian, A, He, C, Chen, Y, Cheng, Y, Jarvis, GA, Keller, MJ, Hogarty, K, Waller, DP, Profy, AT, Herold, BC, and Klotman, ME. "Candidate sulfonated and sulfated topical microbicides: comparison of anti-human immunodeficiency virus activities and mechanisms of action." Antimicrob Agents Chemother 49, no. 9 (September 2005): 3607-3615.  Full Text  Link to Item
    • Schwartz, EJ, Szczech, LA, Ross, MJ, Klotman, ME, Winston, JA, and Klotman, PE. "Highly active antiretroviral therapy and the epidemic of HIV+ end-stage renal disease." J Am Soc Nephrol 16, no. 8 (August 2005): 2412-2420.  Full Text  Link to Item
    • Chang, TL, Vargas, J, DelPortillo, A, and Klotman, ME. "Dual role of alpha-defensin-1 in anti-HIV-1 innate immunity." J Clin Invest 115, no. 3 (March 2005): 765-773.  Full Text  Link to Item
    • Gillim-Ross, L, Cara, A, and Klotman, ME. "Nef expressed from human immunodeficiency virus type 1 extrachromosomal DNA downregulates CD4 on primary CD4+ T lymphocytes: implications for integrase inhibitors." J Gen Virol 86, no. Pt 3 (March 2005): 765-771.  Full Text  Link to Item
    • Chang, TL, Jr, JV, DelPortillo, A, and Klotman, ME. "Dual role of α-defensin-1 in anti-HIV-1 innate immunity." Journal of Clinical Investigation 115, no. 3 (2005): 765-773.  Full Text
    • Gillim-Ross, L, Cara, A, and Klotman, ME. "HIV-1 extrachromosomal 2-LTR circular DNA is long-lived in human macrophages." Viral Immunol 18, no. 1 (2005): 190-196.  Full Text  Link to Item
    • Jing, B, Janout, V, Herold, BC, Klotman, ME, Heald, T, and Regen, SL. "Persulfated molecular umbrellas as anti-HIV and anti-HSV agents." J Am Chem Soc 126, no. 49 (December 15, 2004): 15930-15931.  Full Text  Link to Item
    • He, JC, Husain, M, Sunamoto, M, D'Agati, VD, Klotman, ME, Iyengar, R, and Klotman, PE. "Nef stimulates proliferation of glomerular podocytes through activation of Src-dependent Stat3 and MAPK1,2 pathways." J Clin Invest 114, no. 5 (September 2004): 643-651.  Full Text  Link to Item
    • Chang, TL, and Klotman, ME. "Defensins: natural anti-HIV peptides." AIDS Rev 6, no. 3 (July 2004): 161-168. (Review)  Link to Item
    • Cheshenko, N, Keller, MJ, MasCasullo, V, Jarvis, GA, Cheng, H, John, M, Li, J-H, Hogarty, K, Anderson, RA, Waller, DP, Zaneveld, LJD, Profy, AT, Klotman, ME, and Herold, BC. "Candidate topical microbicides bind herpes simplex virus glycoprotein B and prevent viral entry and cell-to-cell spread." Antimicrob Agents Chemother 48, no. 6 (June 2004): 2025-2036.  Full Text  Link to Item
    • Winston, JA, Klotman, PE, and Klotman, M. "Renal Manifestations of HIV Infection." (April 8, 2004): 651-661. (Chapter)  Full Text
    • Vargas, J, Gusella, GL, Najfeld, V, Klotman, ME, and Cara, A. "Novel integrase-defective lentiviral episomal vectors for gene transfer." Hum Gene Ther 15, no. 4 (April 2004): 361-372.  Full Text  Link to Item
    • He, JC, Husain, M, Sunamoto, M, D'Agati, VD, Klotman, ME, Iyengar, R, and Klotman, PE. "Nef stimulates proliferation of glomerular podocytes through activation of Src-dependent Stat3 and MAPK1,2 pathways." Journal of Clinical Investigation 114, no. 5 (2004): 643-651.  Full Text
    • Ross, MD, Bruggeman, LA, Hanss, B, Sunamoto, M, Marras, D, Klotman, ME, and Klotman, PE. "Podocan, a novel small leucine-rich repeat protein expressed in the sclerotic glomerular lesion of experimental HIV-associated nephropathy." J Biol Chem 278, no. 35 (August 29, 2003): 33248-33255.  Full Text  Link to Item
    • Chang, TL-Y, François, F, Mosoian, A, and Klotman, ME. "CAF-mediated human immunodeficiency virus (HIV) type 1 transcriptional inhibition is distinct from alpha-defensin-1 HIV inhibition." J Virol 77, no. 12 (June 2003): 6777-6784.  Link to Item
    • Hernandez, PA, Gorlin, RJ, Lukens, JN, Taniuchi, S, Bohinjec, J, Francois, F, Klotman, ME, and Diaz, GA. "Mutations in the chemokine receptor gene CXCR4 are associated with WHIM syndrome, a combined immunodeficiency disease." Nat Genet 34, no. 1 (May 2003): 70-74.  Full Text  Link to Item
    • Keller, MJ, Klotman, ME, and Herold, BC. "Rigorous pre-clinical evaluation of topical microbicides to prevent transmission of human immunodeficiency virus." J Antimicrob Chemother 51, no. 5 (May 2003): 1099-1102. (Review)  Full Text  Link to Item
    • Keller, MJ, Klotman, ME, and Herold, BC. "Development of topical microbicides for prevention of human immunodeficiency virus and herpes simplex virus." Am J Reprod Immunol 49, no. 5 (May 2003): 279-284. (Review)  Link to Item
    • François, F, and Klotman, ME. "Phosphatidylinositol 3-kinase regulates human immunodeficiency virus type 1 replication following viral entry in primary CD4+ T lymphocytes and macrophages." J Virol 77, no. 4 (February 2003): 2539-2549.  Link to Item
    • Herold, BC, Scordi-Bello, I, Cheshenko, N, Marcellino, D, Dzuzelewski, M, Francois, F, Morin, R, Casullo, VM, Anderson, RA, Chany, C, Waller, DP, Zaneveld, LJD, and Klotman, ME. "Mandelic acid condensation polymer: novel candidate microbicide for prevention of human immunodeficiency virus and herpes simplex virus entry." J Virol 76, no. 22 (November 2002): 11236-11244.  Link to Item
    • Husain, M, Gusella, GL, Klotman, ME, Gelman, IH, Ross, MD, Schwartz, EJ, Cara, A, and Klotman, PE. "HIV-1 Nef induces proliferation and anchorage-independent growth in podocytes." J Am Soc Nephrol 13, no. 7 (July 2002): 1806-1815.  Link to Item
    • Schwartz, EJ, Fierer, DS, Neumann, AU, Keller, MJ, Parkas, V, Zhang, DY, Klotman, ME, Winston, JA, and Klotman, PE. "HIV-1 dynamics in haemodialysis patients." AIDS 16, no. 9 (June 14, 2002): 1301-1303. (Letter)  Link to Item
    • Marras, D, Bruggeman, LA, Gao, F, Tanji, N, Mansukhani, MM, Cara, A, Ross, MD, Gusella, GL, Benson, G, D'Agati, VD, Hahn, BH, Klotman, ME, and Klotman, PE. "Replication and compartmentalization of HIV-1 in kidney epithelium of patients with HIV-associated nephropathy." Nat Med 8, no. 5 (May 2002): 522-526.  Full Text  Link to Item
    • Gusella, GL, Fedorova, E, Hanss, B, Marras, D, Klotman, ME, and Klotman, PE. "Lentiviral gene transduction of kidney." Hum Gene Ther 13, no. 3 (February 10, 2002): 407-414.  Full Text  Link to Item
    • Cara, A, Vargas, J, Keller, M, Jones, S, Mosoian, A, Gurtman, A, Cohen, A, Parkas, V, Wallach, F, Chusid, E, Gelman, IH, and Klotman, ME. "Circular viral DNA and anomalous junction sequence in PBMC of HIV-infected individuals with no detectable plasma HIV RNA." Virology 292, no. 1 (January 5, 2002): 1-5.  Full Text  Link to Item
    • Chang, TL-Y, Mosoian, A, Pine, R, Klotman, ME, and Moore, JP. "A soluble factor(s) secreted from CD8(+) T lymphocytes inhibits human immunodeficiency virus type 1 replication through STAT1 activation." J Virol 76, no. 2 (January 2002): 569-581.  Link to Item
    • Gusella, GL, Fedorova, E, Marras, D, Klotman, PE, and Klotman, ME. "In vivo gene transfer to kidney by lentiviral vector." Kidney International 61, no. SUPPL. 1 (2002): S32-S36.
    • Gusella, GL, Fedorova, E, Marras, D, Klotman, PE, and Klotman, ME. "In vivo gene transfer to kidney by lentiviral vector." Kidney Int 61, no. 1 Suppl (January 2002): S32-S36.  Full Text  Link to Item
    • Klotman, P, Roseberg, MM, and Klotman, M. "Editorial comment: Renal insufficiency in HIV-infected patients may not always be HIVAN." AIDS Reader 12, no. 6 (2002): 273--.
    • Stern, AS, Klotman, ME, Ioannou, YA, Burrow, CR, Wilson, PD, Klotman, PE, and Lipkowitz, MS. "Polarity of α-galactosidase A uptake by renal tubule cells." Kidney International 61, no. SUPPL. 1 (2002): S52-S55.
    • Stern, AS, Klotman, ME, Ioannou, YA, Burrow, CR, Wilson, PD, Klotman, PE, and Lipkowitz, MS. "Polarity of alpha-galactosidase A uptake by renal tubule cells." Kidney Int 61, no. 1 Suppl (January 2002): S52-S55.  Full Text  Link to Item
    • Huprikar, SS, Datta, SD, Lang, L, and Klotman, ME. "Viral load and CD4 count as predictors of response to hepatitis B vaccine." CLINICAL INFECTIOUS DISEASES 33, no. 7 (October 1, 2001): 1153-1153.  Link to Item
    • Schecter, AD, Berman, AB, Yi, L, Mosoian, A, McManus, CM, Berman, JW, Klotman, ME, and Taubman, MB. "HIV envelope gp120 activates human arterial smooth muscle cells." Proc Natl Acad Sci U S A 98, no. 18 (August 28, 2001): 10142-10147.  Full Text  Link to Item
    • Jones, S, and Klotman, ME. "Impact of genotypic resistance testing on physician selection of antiretroviral therapy." J Hum Virol 4, no. 4 (July 2001): 214-216.  Link to Item
    • Winston, JA, Bruggeman, LA, Ross, MD, Jacobson, J, Ross, L, D'Agati, VD, Klotman, PE, and Klotman, ME. "Nephropathy and establishment of a renal reservoir of HIV type 1 during primary infection." N Engl J Med 344, no. 26 (June 28, 2001): 1979-1984.  Full Text  Link to Item
    • Schecter, AD, Berman, AB, Yi, L, Berman, JW, Klotman, ME, and Taubman, MB. "Human immunodeficiency viral envelope protein, gp120, induces tissue factor activity in human arterial smooth muscle cells." ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 21, no. 4 (April 2001): 690-690.  Link to Item
    • Gillim, L, Gusella, GL, Vargas, J, Marras, D, Klotman, ME, and Cara, A. "Development of a novel screen for protease inhibitors." Clin Diagn Lab Immunol 8, no. 2 (March 2001): 437-440.  Full Text  Link to Item
    • Bruggeman, LA, Ross, MD, Tanji, N, Cara, A, Dikman, S, Gordon, RE, Burns, GC, D'Agati, VD, Winston, JA, Klotman, ME, and Klotman, PE. "Renal epithelium is a previously unrecognized site of HIV-1 infection." J Am Soc Nephrol 11, no. 11 (November 2000): 2079-2087.  Link to Item
    • Jacobson, JM, Lowy, I, Fletcher, CV, O'Neill, TJ, Tran, DN, Ketas, TJ, Trkola, A, Klotman, ME, Maddon, PJ, Olson, WC, and Israel, RJ. "Single-dose safety, pharmacology, and antiviral activity of the human immunodeficiency virus (HIV) type 1 entry inhibitor PRO 542 in HIV-infected adults." J Infect Dis 182, no. 1 (July 2000): 326-329.  Full Text  Link to Item
    • Jones, S, and Klotman, ME. "Access to genotypic resistance testing alters physician selection of antiretroviral therapy." CLINICAL INFECTIOUS DISEASES 31, no. 1 (July 2000): 275-275.  Link to Item
    • Mosoian, A, Teixeira, A, Caron, E, Piwoz, J, and Klotman, ME. "CD8⁺ cell lines isolated from HIV-1-infected children have potent soluble HIV-1 inhibitory activity that differs from β-chemokines." Viral Immunology 13, no. 4 (2000): 481-495.
    • Mosoian, A, Teixeira, A, Caron, E, Piwoz, J, and Klotman, ME. "CD8+ cell lines isolated from HIV-1-infected children have potent soluble HIV-1 inhibitory activity that differs from beta-chemokines." Viral Immunol 13, no. 4 (2000): 481-495.  Full Text  Link to Item
    • Tellier, MC, Greco, G, Klotman, M, Mosoian, A, Cara, A, Arap, W, Ruoslahti, E, Pasqualini, R, and Schnapp, LM. "Superfibronectin, a multimeric form of fibronectin, increases HIV infection of primary CD4⁺ T lymphocytes." Journal of Immunology 164, no. 6 (2000): 3236-3245.
    • Lipkowitz, MS, Hanss, B, Tulchin, N, Wilson, PD, Langer, JC, Ross, MD, Kurtzman, GJ, Klotman, PE, and Klotman, ME. "Transduction of renal cells in vitro and in vivo by adeno-associated virus gene therapy vectors." J Am Soc Nephrol 10, no. 9 (September 1999): 1908-1915.  Link to Item
    • Winston, JA, Klotman, ME, and Klotman, PE. "HIV-associated nephropathy is a late, not early, manifestation of HIV-1 infection." Kidney Int 55, no. 3 (March 1999): 1036-1040. (Review)  Full Text  Link to Item
    • Gelfand, JM, Rudikoff, D, Lebwohl, M, and Klotman, ME. "Effect of UV-B phototherapy on plasma HIV type 1 RNA viral level: a self-controlled prospective study." Arch Dermatol 134, no. 8 (August 1998): 940-945.  Link to Item
    • Gurtman, A, Borrego, F, and Klotman, ME. "Management of antiretroviral therapy." Semin Nephrol 18, no. 4 (July 1998): 459-480. (Review)  Link to Item
    • Langer, JC, Klotman, ME, Hanss, B, Tulchin, N, Bruggeman, LA, Klotman, PE, and Lipkowitz, MS. "Adeno-associated virus gene transfer into renal cells: potential for in vivo gene delivery." Exp Nephrol 6, no. 3 (May 1998): 189-194. (Review)  Link to Item
    • Rivadeneira, ED, Popescu, NC, Zimonjic, DB, Cheng, GS, Nelson, PJ, Ross, MD, DiPaolo, JA, and Klotman, ME. "Sites of recombinant adeno-associated virus integration." Int J Oncol 12, no. 4 (April 1998): 805-810.  Link to Item
    • Klotman, M. "Potential role for G-protein coupled receptors in HIV-associated nephropathy." Kidney International 54, no. 6 (1998): 2243-2244.
    • Klotman, ME, and Klotman, PE. "Seminars in nephrology." Seminars in Nephrology 18, no. 4 (1998): 371-372.
    • Snoeck, HW, Tao, W, and Klotman, ME. "Adeno-associated viral vectors: background and technical aspects." Exp Nephrol 5, no. 6 (November 1997): 514-520. (Review)  Link to Item
    • Cereseto, A, Berneman, Z, Koralnik, I, Vaughn, J, Franchini, G, and Klotman, ME. "Differential expression of alternatively spliced pX mRNAs in HTLV-I-infected cell lines." Leukemia 11, no. 6 (June 1997): 866-870.  Link to Item
    • Lipkowitz, MS, Klotman, ME, Bruggeman, LA, Nicklin, P, Hanss, B, Rappaport, J, and Klotman, PE. "Molecular therapy for renal diseases." Am J Kidney Dis 28, no. 4 (October 1996): 475-492. (Review)  Link to Item
    • Cereseto, A, Diella, F, Mulloy, JC, Cara, A, Michieli, P, Grassmann, R, Franchini, G, and Klotman, ME. "p53 functional impairment and high p21waf1/cip1 expression in human T-cell lymphotropic/leukemia virus type I-transformed T cells." Blood 88, no. 5 (September 1, 1996): 1551-1560.  Link to Item
    • Bruggeman, LA, Thomson, MM, Nelson, PJ, Kopp, JB, Rappaport, J, Klotman, PE, and Klotman, ME. "Patterns of HIV-1 mRNA expression in transgenic mice are tissue-dependent." Virology 202, no. 2 (August 1, 1994): 940-948.  Full Text  Link to Item
    • Santoro, TJ, Bryant, JL, Pellicoro, J, Klotman, ME, Kopp, JB, Bruggeman, LA, Franks, RR, Notkins, AL, and Klotman, PE. "Growth failure and AIDS-like cachexia syndrome in HIV-1 transgenic mice." Virology 201, no. 1 (May 15, 1994): 147-151.  Full Text  Link to Item
    • Gallo, RC, and Klotman, ME. "1993 Annual Meeting of the Laboratory of Tumor Cell Biology: Introduction." AIDS Research and Human Retroviruses 10, no. SUPPL. 1 (1994): S1-.
    • Dhawan, S, Weeks, BS, Abbasi, F, Gralnick, HR, Notkins, AL, Klotman, ME, Yamada, KM, and Klotman, PE. "Increased expression of alpha 4 beta 1 and alpha 5 beta 1 integrins on HTLV-I-infected lymphocytes." Virology 197, no. 2 (December 1993): 778-781.  Full Text  Link to Item
    • Li, G, Lisziewicz, J, Sun, D, Zon, G, Daefler, S, Wong-Staal, F, Gallo, RC, and Klotman, ME. "Inhibition of Rev activity and human immunodeficiency virus type 1 replication by antisense oligodeoxynucleotide phosphorothioate analogs directed against the Rev-responsive element." J Virol 67, no. 11 (November 1993): 6882-6888.  Link to Item
    • Weeks, BS, Klotman, ME, Holloway, E, Stetler-Stevenson, WG, Kleinman, HK, and Klotman, PE. "HIV-1 infection stimulates T cell invasiveness and synthesis of the 92-kDa type IV collagenase." AIDS Res Hum Retroviruses 9, no. 6 (June 1993): 513-518.  Full Text  Link to Item
    • Weeks, BS, Desai, K, Loewenstein, PM, Klotman, ME, Klotman, PE, Green, M, and Kleinman, HK. "Identification of a novel cell attachment domain in the HIV-1 Tat protein and its 90-kDa cell surface binding protein." J Biol Chem 268, no. 7 (March 5, 1993): 5279-5284.  Link to Item
    • Koralnik, IJ, Gessain, A, Klotman, ME, Lo Monico, A, Berneman, ZN, and Franchini, G. "Protein isoforms encoded by the pX region of human T-cell leukemia/lymphotropic virus type I." Proc Natl Acad Sci U S A 89, no. 18 (September 15, 1992): 8813-8817.  Link to Item
    • Perfect, JR, Klotman, ME, Gilbert, CC, Crawford, DD, Rosner, GL, Wright, KA, and Peters, WP. "Prophylactic intravenous amphotericin B in neutropenic autologous bone marrow transplant recipients." J Infect Dis 165, no. 5 (May 1992): 891-897.  Link to Item
    • Berneman, ZN, Gartenhaus, RB, Reitz, MS, Blattner, WA, Manns, A, Hanchard, B, Ikehara, O, Gallo, RC, and Klotman, ME. "Expression of alternatively spliced human T-lymphotropic virus type I pX mRNA in infected cell lines and in primary uncultured cells from patients with adult T-cell leukemia/lymphoma and healthy carriers." Proc Natl Acad Sci U S A 89, no. 7 (April 1, 1992): 3005-3009.  Link to Item
    • Kopp, JB, Klotman, ME, Adler, SH, Bruggeman, LA, Dickie, P, Marinos, NJ, Eckhaus, M, Bryant, JL, Notkins, AL, and Klotman, PE. "Progressive glomerulosclerosis and enhanced renal accumulation of basement membrane components in mice transgenic for human immunodeficiency virus type 1 genes." Proc Natl Acad Sci U S A 89, no. 5 (March 1, 1992): 1577-1581.  Link to Item
    • Klotman, ME, Kim, SY, Buchbinder, A, DeRossi, A, Baltimore, D, and Wong-Staal, F. "Kinetics of expression of multiply spliced RNA in early human immunodeficiency virus type 1 infection of lymphocytes and monocytes." Proc Natl Acad Sci U S A 89, no. 3 (February 1, 1992): 1148-.  Link to Item
    • Berneman, ZN, Gartenhaus, RB, Reitz, MS, Klotman, ME, and Gallo, RC. "cDNA sequencing confirms HTLV-I expression in adult T-cell leukemia/lymphoma and different sequence variations in vivo and in vitro." Leukemia 6 Suppl 3 (1992): 67S-71S.  Link to Item
    • Klotman, ME, Kim, S, Buchbinder, A, DeRossi, A, Baltimore, D, and Wong-Staal, F. "Erratum: Kinetics of expression of multiply spliced RNA in early human immunodeficiency virus type 1 infection of lymphocytes and monocytes (Proc. Natl. Acad. Sci. USA (June 1991) 88 (5011-5015))." Proceedings of the National Academy of Sciences of the United States of America 89, no. 3 (1992): 1148--.
    • Lisziewicz, J, Sun, D, Klotman, M, Agrawal, S, Zamecnik, P, and Gallo, R. "Specific inhibition of human immunodeficiency virus type 1 replication by antisense oligonucleotides: An in vitro model for treatment." Proceedings of the National Academy of Sciences of the United States of America 89, no. 23 (1992): 11209-11213.  Full Text
    • Gartenhaus, RB, Wong-Staal, F, and Klotman, ME. "The promoter of human T-cell leukemia virus type-I is repressed by the immediate-early gene region of human cytomegalovirus in primary blood lymphocytes." Blood 78, no. 11 (December 1, 1991): 2956-2961.  Link to Item
    • Weeks, BS, Klotman, ME, Dhawan, S, Kibbey, M, Rappaport, J, Kleinman, HK, Yamada, KM, and Klotman, PE. "HIV-1 infection of human T lymphocytes results in enhanced alpha 5 beta 1 integrin expression." J Cell Biol 114, no. 4 (August 1991): 847-853.  Link to Item
    • Klotman, ME, Kim, S, Buchbinder, A, DeRossi, A, Baltimore, D, and Wong-Staal, F. "Kinetics of expression of multiply spliced RNA in early human immunodeficiency virus type 1 infection of lymphocytes and monocytes." Proc Natl Acad Sci U S A 88, no. 11 (June 1, 1991): 5011-5015.  Link to Item
    • Daefler, S, Klotman, ME, and Wong-Staal, F. "Trans-activating rev protein of the human immunodeficiency virus 1 interacts directly and specifically with its target RNA." Proc Natl Acad Sci U S A 87, no. 12 (June 1990): 4571-4575.  Link to Item
    • Shaunak, S, Albright, RE, Klotman, ME, Henry, SC, Bartlett, JA, and Hamilton, JD. "Amplification of HIV-1 provirus from cerebrospinal fluid and its correlation with neurologic disease." J Infect Dis 161, no. 6 (June 1990): 1068-1072.  Link to Item
    • Sadaie, MR, Tschachler, E, Valerie, K, Rosenberg, M, Felber, BK, Pavlakis, GN, Klotman, ME, and Wong-Staal, F. "Activation of tat-defective human immunodeficiency virus by ultraviolet light." New Biol 2, no. 5 (May 1990): 479-486.  Link to Item
    • Klotman, ME, Henry, SC, Greene, RC, Brazy, PC, Klotman, PE, and Hamilton, JD. "Detection of mouse cytomegalovirus nucleic acid in latently infected mice by in vitro enzymatic amplification." J Infect Dis 161, no. 2 (February 1990): 220-225.  Link to Item
    • Kim, JH, Cooper, RA, Welty-Wolf, KE, Harrell, LJ, Zwadyk, P, and Klotman, ME. "Pseudomonas putrefaciens bacteremia." Rev Infect Dis 11, no. 1 (January 1989): 97-104.  Link to Item
    • Peters, WP, Stuart, A, Klotman, M, Gilbert, C, Jones, RB, Shpall, EJ, Gockerman, J, Bast, RC, and Moore, JO. "High-dose combination cyclophosphamide, cisplatin, and melphalan with autologous bone marrow support. A clinical and pharmacologic study." Cancer Chemother Pharmacol 23, no. 6 (1989): 377-383.  Link to Item
    • Schmader, KE, van der Horst, CM, and Klotman, ME. "Epstein-Barr virus and the elderly host." Rev Infect Dis 11, no. 1 (January 1989): 64-73. (Review)  Link to Item
    • Buchbinder, A, Josephs, SF, Ablashi, D, Salahuddin, SZ, Klotman, ME, Manak, M, Krueger, GR, Wong-Staal, F, and Gallo, RC. "Polymerase chain reaction amplification and in situ hybridization for the detection of human B-lymphotropic virus." J Virol Methods 21, no. 1-4 (September 1988): 191-197.  Link to Item
    • Klotman, ME, Henry, SC, and Hamilton, JD. "Determinants of the source of cytomegalovirus in murine renal allograft recipients." Transplantation 44, no. 5 (November 1987): 636-639.  Link to Item
    • Klotman, ME, and Hamilton, JD. "Cytomegalovirus pneumonia." Semin Respir Infect 2, no. 2 (June 1987): 95-103. (Review)  Link to Item
    • Klotman, ME, Starnes, D, and Hamilton, JD. "The source of murine cytomegalovirus in mice receiving kidney allografts." J Infect Dis 152, no. 6 (December 1985): 1192-1196.  Link to Item
    • Klotman, ME. "Laboratory detection of urinary tract infections." Kidney 18, no. 1 (1985): 1-4.
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