Scholars@Duke
Edward Wayne Massey

Edward Wayne Massey

Professor Emeritus of Neurology
Neurology, Comprehensive Neurology
wayne.massey@duke.edu
Duke Box 3909, Durham, NC 27710
122-B Baker House, Durham, NC 27710

Scholarly Works

Mononeuropathies in pregnancy.

Book section · 2020 While signs and symptoms of peripheral neuropathy may appear to be similar among all patients, further evaluation both at the bedside and beyond demonstrate distinct differences in the pattern of certain neuropathies. A working knowledge of these differenc ... Full text Link to item Cite

Ultrasound in EMG-Guided Biopsies: A Prospective, Randomized Pilot Trial.

Journal article Muscle Nerve · October 2016 INTRODUCTION: At our institution, core muscle biopsies are performed on muscles selected using electromyography (EMG). Ultrasound (US) guidance is not used routinely. The aim of this study was to determine if US guidance of EMG selected muscles would incre ... Full text Link to item Cite

Diagnostic, medical, and surgical approaches to stroke management

Book section · September 19, 2014 Hemorrhagic and ischemic brain damage causing stroke ranks third among the causes of death in the United States. The evaluation of patients with stroke must be extensive and the approach is reviewed. Epidemiologic data suggest a decreased incidence of both ... Cite

Peripheral neuropathies in pregnancy.

Journal article Continuum (Minneap Minn) · February 2014 PURPOSE OF REVIEW: This article provides an overview of the most common peripheral neuropathic disorders in pregnancy with a focus on clinical recognition, diagnosis, and treatment. RECENT FINDINGS: The literature on this topic consists primarily of case r ... Full text Link to item Cite

Neurology and diving.

Journal article Handb Clin Neurol · 2014 Diving exposes a person to the combined effects of increased ambient pressure and immersion. The reduction in pressure when surfacing can precipitate decompression sickness (DCS), caused by bubble formation within tissues due to inert gas supersaturation. ... Full text Link to item Cite

Neuromuscular disorders in pregnancy.

Journal article Neurol Clin · August 2012 Preexisting and coincident neuromuscular disorders in pregnancy are challenging for clinicians because of the heterogeneity of disease and the limited data in the literature. Many questions arise regarding the effect of disease on the pregnancy, delivery, ... Full text Link to item Cite

Carbon monoxide, skeletal muscle oxidative stress, and mitochondrial biogenesis in humans.

Journal article Am J Physiol Heart Circ Physiol · July 2009 Given that the physiology of heme oxygenase-1 (HO-1) encompasses mitochondrial biogenesis, we tested the hypothesis that the HO-1 product, carbon monoxide (CO), activates mitochondrial biogenesis in skeletal muscle and enhances maximal oxygen uptake (Vo(2m ... Full text Link to item Cite

Neurologic injuries from scuba diving.

Journal article Phys Med Rehabil Clin N Am · February 2009 Interest in scuba (self-contained underwater breathing apparatus) diving increased in the 1970s, and undersea diving continues to be a popular sport early in the 21st century, with approximately 3 million certified divers in the United States. The Divers A ... Full text Link to item Cite

Spinal accessory nerve lesions.

Journal article Semin Neurol · February 2009 The spinal accessory nerve, primarily a motor nerve, innervates the sternocleidomastoid and trapezius muscles. Proximally, lesions can occur intracranially at the skull base or just outside the jugular foramen producing ipsilateral weakness of trapezius an ... Full text Link to item Cite

Visual function 15 years after optic neuritis: a final follow-up report from the Optic Neuritis Treatment Trial.

Journal article Ophthalmology · June 2008 OBJECTIVE: To assess visual function 15 years after acute unilateral optic neuritis. DESIGN: Longitudinal follow-up of a randomized clinical trial. PARTICIPANTS: Two hundred ninety-four patients who were randomized in the Optic Neuritis Treatment Trial bet ... Full text Link to item Cite

Multiple sclerosis risk after optic neuritis: final optic neuritis treatment trial follow-up.

Journal article Arch Neurol · June 2008 OBJECTIVE: To assess the risk of developing multiple sclerosis (MS) after optic neuritis and the factors predictive of high and low risk. DESIGN: Subjects in the Optic Neuritis Treatment Trial, who were enrolled between July 1, 1988, and June 30, 1991, wer ... Full text Link to item Cite

Neurologic injuries from scuba diving.

Journal article Neurol Clin · February 2008 Interest in scuba (self-contained underwater breathing apparatus) diving increased in the 1970s, and undersea diving continues to be a popular sport early in the 21st century, with approximately 3 million certified divers in the United States. The Divers A ... Full text Link to item Cite

Peripheral neuropathy in pregnancy.

Journal article Phys Med Rehabil Clin N Am · February 2008 Peripheral neuropathy, mononeuropathy and polyneuropathy, are not common in pregnancy. When complaints occur, however, even if minor, they can be bothersome to the pregnant woman. Peripheral nerve function may threaten the mother and fetus in various ways ... Full text Link to item Cite

Subacute combined degeneration due to copper deficiency.

Journal article J Neuroimaging · October 2007 There is growing clinical evidence supporting a connection between copper deficiency and subacute combined degeneration. While nearly half of patients with copper deficiency myelopathy exhibit MRI abnormalities, signal changes are often ill-defined in dist ... Full text Link to item Cite

Sural neuropathy: etiologies and predisposing factors.

Journal article Muscle Nerve · October 2006 Isolated sural neuropathy is an uncommon diagnosis. We identified 36 patients with isolated sural neuropathy. Sixteen had various forms of ankle trauma, in three of whom the associated sural neuropathies developed following medical intervention. Three pati ... Full text Link to item Cite

Neurologic Consequences of Diving

Journal article · January 1, 2003 Full text Cite

Internal carotid artery dissection in stroke from SCUBA diving: a case report.

Journal article Undersea Hyperb Med · 2002 Although diving with compressed air is generally safe, neurological problems resulting from infarction in SCUBA diving are well known, including arterial gas embolism and decompression sickness (caisson's disease, bends) involving the brain and spinal cord ... Link to item Cite

Poststroke pruritus.

Journal article Stroke · March 1999 Full text Link to item Cite

Sensory mononeuropathies.

Journal article Semin Neurol · 1998 The clinical neurologist frequently encounters patients with a variety of focal sensory symptoms and signs. This article reviews the clinical features, etiologies, laboratory findings, and management of the common sensory mononeuropathies including meralgi ... Full text Link to item Cite

Spinal cord infarction: Reply from the authors

Journal article Neurology · January 1, 1997 Full text Cite

Spinal cord infarction: etiology and outcome.

Journal article Neurology · August 1996 We reviewed 44 cases of ischemia and infarction of the spinal cord at two university hospitals. Three patients experienced transient ischemic attacks. Etiologies of completed strokes were diverse and included rupture and surgical repair of aortic aneurysms ... Full text Link to item Cite

Treatment of radiation-induced nervous system injury with heparin and warfarin.

Journal article Neurology · November 1994 When radiation is used to treat nervous system cancer, exposure of adjacent normal nervous system tissue is unavoidable, and radiation-induced injury may occur. Acute injury is usually mild and transient, but late forms of radiation-induced nervous system ... Full text Link to item Cite

Presenting pulse pressure predicts thrombolytic therapy-related intracranial hemorrhage. Thrombolytic Predictive Instrument (TPI) Project results.

Journal article Circulation · October 1994 BACKGROUND: In selecting patients with acute myocardial infarction for thrombolytic therapy, it is important to identify patients who are at high risk for intracranial hemorrhage, for whom thrombolytic therapy is ill advised. We hypothesized that presentin ... Full text Link to item Cite

Cerebral imaging of decompression injury patients with 18-F-2-fluoro-2-deoxyglucose positron emission tomography.

Journal article Undersea Hyperb Med · June 1994 The objective assessment of the extent of cerebral insult and the effects of therapy in decompression injury patients has proven to be difficult by most imaging modalities. In this pilot study we evaluated the ability of 18-F-2-fluoro-2-deoxyglucose (FDG) ... Link to item Cite

A follow-up survey of clinical practices for the use of heparin, warfarin, and aspirin.

Journal article Neurology · April 1994 OBJECTIVE: To determine whether anticoagulation practices have changed when heparin and warfarin are used to treat cerebrovascular disease, and to determine the dosage of aspirin used to treat carotid territory transient ischemic attacks (TIAs). BACKGROUND ... Full text Link to item Cite

Wernicke-Korsakoff syndrome caused by psychogenic food refusal: MR findings.

Journal article AJNR Am J Neuroradiol · March 1994 A 37-year-old woman developed Wernicke encephalopathy after prolonged psychogenic food refusal. MR revealed characteristic signal abnormalities in the midbrain and dorsal thalamus. Follow-up scans showed atrophy and third ventricular enlargement. Wernicke ... Link to item Cite

Ipecac myopathy and cardiomyopathy.

Journal article J Neurol Neurosurg Psychiatry · May 1993 Two cases of ipecac myopathy, one with associated cardiomyopathy are reported. Both patients were young women with eating disorders who came to medical attention because of diffuse muscle weakness. Clinical and electromyographic data suggested ipecac myopa ... Full text Link to item Cite

Aspiration in bilateral stroke patients: a validation study.

Journal article Neurology · February 1993 We validated the predictive accuracy of an "old" regression model in a "new" sample of bilateral stroke patients (N = 38). Abnormal gag reflex and impaired voluntary cough accurately predicted radiographically verified aspiration in both samples. A final m ... Full text Link to item Cite

Diminished subcortical nuclei volumes in Parkinson's disease by MR imaging.

Journal article J Neural Transm Suppl · 1993 Parkinson's disease (PD) is associated with changes in the substantia nigra, which communicates with subcortical nuclei. This study investigates subcortical nuclei volume in PD in vivo by magnetic resonance (MR) imaging. Caudate, putaminal, and thalamic nu ... Link to item Cite

Neurologic injury from undersea diving.

Journal article Neurol Clin · November 1992 Underwater diving may cause several unique neurologic injuries because of exposure to rapid changes in pressure and volume. DCS, which results from extended deep dives and too rapid ascent, is a systemic disease that frequently causes spinal cord injury bu ... Link to item Cite

Shoulder pain from glomus tumour.

Journal article J Neurol Neurosurg Psychiatry · May 1992 Full text Link to item Cite

CNS mycosis fungoides: CT and MR findings.

Journal article J Comput Assist Tomogr · 1992 Mycosis fungoides (MF) is a malignant T-cell lymphoma that primarily involves the skin, but may, in its advanced stages, metastasize to internal organs. From autopsy series, CNS involvement of MF can be seen in 14% of patients. We describe the CT and MR fi ... Full text Link to item Cite

How to check ankle reflexes

Journal article Postgraduate Medicine · January 1, 1992 Cite

CT patterns of intracranial hemorrhage complicating thrombolytic therapy for acute myocardial infarction.

Journal article Radiology · November 1991 Computed tomographic (CT) patterns of intracranial hemorrhage (ICH) were determined in 1,696 patients undergoing thrombolytic therapy for acute myocardial infarction. ICH occurred at 33 sites in 0.77% of patients (n = 13). Thirty-six percent of hemorrhages ... Full text Link to item Cite

Managing dysphagia. Special problems in patients with neurologic disease.

Journal article Postgrad Med · April 1991 Swallowing is a brief but intricate process. When this process is interrupted, as in patients with neurologic disorders, problems such as aspiration and risk of malnutrition can occur. The authors of this article discuss an individualized approach to evalu ... Full text Link to item Cite

Therapy of seizures associated with stroke.

Journal article Clin Neuropharmacol · February 1991 Full text Link to item Cite

Aspiration in bilateral stroke patients.

Journal article Neurology · November 1990 Seventy patients with bilateral strokes underwent neurologic and videofluoroscopic barium swallowing examinations; 34 (48.6%) aspirated. Patients with aspiration were more likely to have posterior circulation strokes, abnormal cough, abnormal gag, and dysp ... Full text Link to item Cite

Bell's palsy. Ensuring the best possible outcome.

Journal article Postgrad Med · October 1990 Bell's palsy is thought to be an idiopathic polyneuritis and must be distinguished from other disorders that cause facial weakness. In most cases, differentiation can be accomplished on the basis of the history, physical examination, and clinical course. R ... Full text Link to item Cite

Large-dose infusions of heparinoid ORG 10172 in ischemic stroke.

Journal article Stroke · September 1990 We evaluated the safety and possible efficacy of large doses of the heparinoid ORG 10172 in 57 patients with acute or progressing ischemic stroke. Patients received a loading bolus of the drug followed by a maintenance intravenous infusion for 7 days. The ... Full text Link to item Cite

Stroke and acute myocardial infarction in the thrombolytic era: clinical correlates and long-term prognosis.

Journal article J Am Coll Cardiol · September 1990 Thirteen (1.8%) of 708 patients with acute myocardial infarction treated with recombinant tissue-type plasminogen activator in the Thrombolysis and Angioplasty in Myocardial Infarction (TAMI) I, II and III trials developed a stroke. Four strokes were hemor ... Full text Link to item Cite

Tourette's syndrome. Tics, jerks, and quirks.

Journal article Postgrad Med · February 1, 1990 Over the past 20 years, public and physician awareness of tic disorders, including Tourette's syndrome, has increased remarkably. In fact, Tourette's syndrome is now "diagnosed" by many families before they consult a physician. Patients seek help not only ... Full text Link to item Cite

Frontal lobe trauma in the elderly. Personality changes aren't always dementia.

Journal article Postgrad Med · September 1, 1989 Changes in personality and behavior are fairly specific when they are caused by damage to the frontal lobe of the cerebral cortex. They are characterized by changes in affect and in emotional response and may be pseudopsychopathic, pseudodepressive, or a c ... Full text Link to item Cite

Neurologic manifestations of hematologic disease.

Journal article Neurol Clin · August 1989 Hematologic diseases may affect the nervous system. Abnormalities in the cellular components, impaired flow, abnormal clotting, or tendency to bleed may all produce neurologic symptoms and signs. A systematic approach to these etiologies is important. ... Link to item Cite

Hand weakness in elderly patients.

Journal article Postgrad Med · March 1989 Weakness of the hand is a common problem in the elderly. When joint and vascular diseases have been ruled out, a systematic anatomic approach to the possible neurologic causes can be used to sort through nonspecific symptoms and the complexity of hand anat ... Full text Link to item Cite

A dose escalation study of ORG 10172 (low molecular weight heparinoid) in stroke.

Journal article Neurology · February 1989 An intravenous infusion of a low molecular weight heparinoid, with a reduced risk of hemorrhage, may be an alternative to heparin in the management of acute ischemic stroke. To evaluate this hypothesis, we studied the safety of the heparinoid, ORG 10172, i ... Full text Link to item Cite

Task-Dependent Neglect: Computed Tomography Size and Locus Correlations

Journal article Neurorehabilitation and Neural Repair · January 1, 1989 We studied the severity and task-specific nature of neglect in relation to brain lesion size and locus in 23 right hemisphere stroke patients. We used five visuospatial tasks, including reading and writing. No single task identified hemispatial neglect in ... Full text Cite

A dose escalation study of ORG 10172 (low molecular weight heparinoid) in stroke

Journal article Neurology · 1989 An intravenous infusion of a low molecular weight heparinoid, with a reduced risk of hemorrhage, may be an alternative to heparin in the management of acute ischemic stroke. To evaluate this hypothesis, we studied the safety of the heparinoid, ORG 10172, i ... Cite

Babinski's sign in medieval, Renaissance, and baroque art.

Journal article Arch Neurol · January 1989 In 1896, Joseph François Babinski first described his well-known sign of dorsiflexion of the big toe on stimulating the sole of the foot. However, unknown to Babinski, several painters had previously demonstrated this phenomenon in their paintings. Sandro ... Full text Link to item Cite

Neuroimaging of scuba diving injuries to the CNS.

Journal article AJR Am J Roentgenol · November 1988 Diving accidents related to barotrauma constitute a unique subset of ischemic insults to the CNS. Victims may demonstrate components of arterial gas embolism, which has a propensity for cerebral involvement, and/or decompression sickness, with primarily sp ... Full text Link to item Cite

Aspiration following stroke: clinical correlates and outcome.

Journal article Neurology · September 1988 Among 47 patients with stroke evaluated clinically and videofluoroscopically, one-half aspirated. Patients with combined cerebral-brainstem strokes with bilateral cranial nerve signs were at greatest risk, but aspiration also occurred in the context of uni ... Full text Link to item Cite

Mononeuropathies in pregnancy.

Journal article Semin Neurol · September 1988 Full text Link to item Cite

Granulomatous angiitis of the central nervous system: protean manifestations and response to treatment.

Journal article J Neurol Neurosurg Psychiatry · September 1988 Granulomatous angiitis is an uncommon necrotising vasculitis of unknown cause restricted to vessels of the central nervous system. Five tissue-proven cases emphasise the protean manifestations of this disease and the difficulties encountered in reaching a ... Full text Link to item Cite

International mortality from primary nervous system neoplasms: distribution and trends.

Journal article Int J Epidemiol · March 1988 International comparisons of average annual age-adjusted mortality rates for primary tumours of the nervous system for 1951 through 1958 and 1967 through 1973 showed marked geographical variation for both study periods. For the majority of countries, the m ... Full text Link to item Cite

Silent aspiration following stroke.

Journal article Neurology · February 1988 Neurogenic dysphagia following stroke is not limited to brainstem involvement. Among 21 patients with stroke, one-third demonstrated only unilateral signs. In eight patients with silent aspiration, less subjective complaints, weaker cough, and dysphonia oc ... Full text Link to item Cite

Neuroimaging of scuba diving injuries to the CNS

Journal article American Journal of Neuroradiology · January 1, 1988 Diving accidents related to barotrauma constitute a unique subset of ischemic insults to the CNS. Victims may demonstrate components of arterial gas embolism, which has a propensity for cerebral involvement, and/or decompression sickness, with primarily sp ... Cite

Erythrocyte sedimentation rate in temporal arteritis.

Journal article South Med J · December 1987 Some authors have reported that the erythrocyte sedimentation rate (ESR) is elevated in almost all patients with biopsy-proven temporal arteritis, while others believe it may be normal in up to 30% of such patients. We studied 62 patients with biopsy-prove ... Full text Link to item Cite

A multicenter study of anticoagulation parameters when using heparin and warfarin.

Journal article Arch Neurol · December 1987 Anticoagulation with heparin and warfarin is used in the treatment of several diseases including cerebrovascular disease. While the most effective therapeutic range of anticoagulation is unclear, some investigators have found an increased risk of bleeding ... Full text Link to item Cite

Aspartame and susceptibility to headache.

Journal article N Engl J Med · November 5, 1987 We performed a double-blind crossover trial of challenges with 30 mg of aspartame per kilogram of body weight or placebo in 40 subjects who reported having headaches repeatedly after consuming products containing aspartame. The incidence rate of headache a ... Full text Link to item Cite

Chorea-acanthocytosis: a report of three new families and implications for genetic counselling.

Journal article Am J Med Genet · October 1987 Chorea-acanthocytosis (CHA) is a rare inherited neurologic disorder with peripheral red cell acanthocytes and normal serum lipoprotein levels. To date, 8 families with the disorder have been reported outside of Japan. We describe 4 patients in 3 families w ... Full text Link to item Cite

A boy (a bleeder) and a bloody revolution.

Journal article N C Med J · March 1987 Link to item Cite

Facial diplegia due to amyloidosis.

Journal article South Med J · November 1986 In a 61-year-old man with facial diplegia and new onset of congestive heart failure (CHF), electroneuromyography indicated diffuse axonal degeneration, but sural nerve biopsy showed mild changes and no amyloid. Four months later, after the onset of diplopi ... Full text Link to item Cite

Forearm neuropathy and pruritus.

Journal article South Med J · October 1986 Five adult patients (four of them men) had episodic brachioradial pruritus associated with forearm paresthesia and hypalgesia. No cervical, shoulder, or forearm trauma was known. Onset was variable, but two had had the condition for more than ten years. In ... Full text Link to item Cite

Botulinum toxin for blepharospasm: single-fiber EMG studies.

Journal article Neurology · April 1986 In four patients who received periocular injections of botulinum toxin for blepharospasm, abnormal neuromuscular transmission was demonstrated by single-fiber EMG in arm muscles. The time course with which the abnormalities developed and cleared, as well a ... Full text Link to item Cite

Evoked potentials in choreoacanthocytosis.

Journal article Electroencephalogr Clin Neurophysiol · April 1986 Visual, brain-stem auditory and somatosensory evoked potentials were obtained in two patients with choreoacanthocytosis. Only minor SSEP amplitude reduction was found in one patient. Therefore evoked potentials were not helpful in identifying patients with ... Full text Link to item Cite

Dynamic spelling alexia.

Journal article J Neurol Neurosurg Psychiatry · April 1986 A 59-year-old, right-handed, college-educated male examined after stroke presented spelling alexia with relative sparing of writing. He was not aphasic. A striking feature of the alexia was preserved recognition of letters printed in view by the clinician. ... Full text Link to item Cite

Forearm neuropathy and pruritus

Journal article Southern Medical Journal · January 1, 1986 Five adult patients (four of them men) had episodic brachioradial pruritus associated with forearm paresthesia and hypalgesia. No cervical, shoulder, or forearm trauma was known. Onset was variable, but two had had the condition for more than ten years. In ... Cite

Therapy for granulomatous angiitis.

Journal article Clin Neuropharmacol · 1986 The clinical diagnosis of granulomatous angiitis can be extremely difficult because of the diversity of presentation. A clinical presentation of progressive multifocal encephalopathy is most common but signs suggesting isolated mass lesions or dementia may ... Full text Link to item Cite

Neurologic complications of Rocky Mountain spotted fever.

Journal article South Med J · November 1985 Rocky Mountain spotted fever, a serious systemic infectious illness, is common in the southeastern United States. Approximately one fourth of the cases in the United States occur in North Carolina. Widespread organ involvement occurs, with central nervous ... Full text Link to item Cite

Lumbosacral plexus stretch injury following the use of the modified lithotomy position.

Journal article J Urol · September 1985 The modified lithotomy position is used to provide simultaneous operative exposure to the abdomen and perineum. We report 3 lumbosacral plexus complications following use of this position. A mechanism involving stretch secondary to hyperabduction seems mos ... Full text Link to item Cite

Cerebral infarction in sickle cell trait.

Journal article Ann Neurol · September 1985 Sickle cell disease is known to predispose patients to the risk of cerebral infarction. However, only scattered reports exist of the neurological sequelae of the sickle cell trait. Only 8 cases are reported in the English literature, in some of which the s ... Full text Link to item Cite

Neurologic presentation of decompression sickness and air embolism in sport divers.

Journal article Neurology · May 1985 In a retrospective study of scuba divers with neurologic injuries, we found that mild symptoms were common. Seventy divers had decompression sickness, most often with paresthesias or numbness, rarely with paresis. Thirty-nine divers had air embolism that o ... Full text Link to item Cite

Essential vocal tremor: clinical characteristics and response to therapy.

Journal article South Med J · March 1985 We evaluated four patients with an initial and predominant voice tremor. All were referred for evaluation for suspected parkinsonism, though vocal tremor was the only symptom. These three women and one man ranged in age from 37 to 59 years. Neurologic eval ... Link to item Cite

Common mononeuropathies.

Journal article N C Med J · January 1985 Link to item Cite

Motor neuron disease presenting with respiratory failure. Report of two cases.

Journal article Postgrad Med · December 1984 In the two cases reported here, acute respiratory failure developed as a manifestation of motor neuron disease (amyotrophic lateral sclerosis). Both patients complained of systemic weakness before respiratory failure occurred. In one patient, respiratory s ... Full text Link to item Cite

Myocardial infarction and stroke.

Journal article Neurology · November 1984 We used a computer data bank to evaluate 740 consecutive patients admitted to a cardiac care unit with myocardial infarction. Stroke occurred in 18 (2.4%) patients in the hospital; the anterior circulation was involved in 76% of strokes. Hospital mortality ... Full text Link to item Cite

Seizures activated by therapeutic levels of lithium carbonate.

Journal article South Med J · September 1984 We have described a 22-year-old woman who manifested clinical seizures after treatment with lithium carbonate was initiated. Serial electroencephalograms showed both nonspecific activation and activation of an epileptiform discharge with serum levels of li ... Full text Link to item Cite

Arsenic: homicidal intoxication.

Journal article South Med J · July 1984 Arsenic-induced deaths have been known to occur from accidental poisoning, as a result of medical therapy, and from intentional poisonings in homicide and suicide. Twenty-eight arsenic deaths in North Carolina from 1972 to 1982 included 14 homicides and se ... Link to item Cite

Foster Kennedy syndrome.

Journal article Arch Neurol · June 1984 Full text Link to item Cite

Ergot, the "jerks," and revivals.

Journal article Clin Neuropharmacol · 1984 Epidemics of epilepsy, a form of mass hysteria, were known in Eastern and Western cultures in the 17th and 18th centuries. A unique situation in the United States during the 19th centurey was the frontier religious movement, the setting in which the "jerks ... Full text Link to item Cite

Dyskinesias associated with lithium therapy in parkinsonism.

Journal article Clin Neuropharmacol · 1984 Five patients with the "on-off" phenomenon of parkinsonism who developed dyskinesias associated with a reduction in akinesia during treatment with lithium carbonate are described. The data show that lithium-induced dyskinesias may occur in the absence of l ... Full text Link to item Cite

Cranial nerve paralysis following carotid endarterectomy.

Journal article Stroke · 1984 During the past seven years 347 patients have been entered into a data bank at the Duke University Medical Center for evaluation of transient neurologic ischemia. One hundred fifty eight of these patients had carotid endarterectomies of whom 24 (15.1%) dev ... Full text Link to item Cite

Natural history of cerebral complications of coronary artery bypass graft surgery.

Journal article Neurology · November 1983 We reviewed 1,669 patients who survived coronary artery bypass graft surgery between 1969 and 1981. A total of 75 cerebral complications were identified, including (1) altered mental state, (2) stroke, and (3) seizure in 64 patients (3.8%). Altered mental ... Full text Link to item Cite

Neurologic manifestations of essential thrombocythemia.

Journal article Ann Intern Med · October 1983 Essential thrombocythemia is a clonal myeloproliferative disorder, characterized predominantly by a markedly elevated platelet count without known cause. We report a case that was recognized during investigation of a transient ischemic attack, and review t ... Full text Link to item Cite

Delirium: diagnosis and treatment.

Journal article South Med J · September 1983 Link to item Cite

Digitalgia paresthetica with digital neuropathy in rheumatoid arthritis.

Journal article South Med J · July 1983 Two cases demonstrate the digital neuropathy of rheumatoid arthritis with hyperpathia. This phenomenon occurs in types II and IV, but the paresthetic character has not been emphasized previously. ... Full text Link to item Cite

Frontal lobe personality syndromes. Ominous sequelae of head trauma.

Journal article Postgrad Med · May 1983 Head trauma frequently results in frontal lobe dysfunction. This can cause a number of personality changes characterized by disturbances in affect and in regulation of emotions. Behavioral changes and alterations in cognition may occur also and are often a ... Full text Link to item Cite

Hand weakness in the elderly.

Journal article J Am Geriatr Soc · April 1983 Hand weakness is an important but frequently overlooked problem in the elderly. The exact diagnosis is often difficult because of the complexities of innervation and muscle function. An anatomic approach to the diagnosis of isolated hand weakness in the el ... Full text Link to item Cite

Pneumocephaly from epidural anesthesia.

Journal article South Med J · March 1983 An elderly woman who had spinal epidural anesthesia thereafter had headache, anorexia, nausea and vomiting, dehydration, seizures, and cardiovascular collapse. CAT scan revealed air in the posterior fossa, probably caused by intradural injection of air dur ... Full text Link to item Cite

Occurrence of stroke following coronary artery bypass graft surgery

Journal article Cardiovascular Reviews and Reports · January 1, 1983 Cite

Mortality from cerebrovascular disease: International comparisons and temporal trends

Journal article Neuroepidemiology · January 1, 1983 Average annual cerebrovascular disease (CVD) mortality rates (age-adjusted to the 1950 US population) were calculated using data from 1967 through 1973 for 33 countries. Rates range from 35.8/100, 000/year (Philippines) to 196.7/100, 000/year (Japan). Ther ... Full text Cite

International mortality from primary nervous system neoplasms: Distribution and trends

Journal article Neuroepidemiology · January 1, 1983 International comparisons of average annual age-adjusted mortality rates for primary tumors of the nervous system for 1951-1958 and 1967-1973 showed marked geographic variation for both study periods. For the majority of countries, the mortality rates incr ... Full text Cite

Progressive dysfluency associated with right hemisphere disease.

Journal article Brain Lang · January 1983 A late onset progressive dysfluency following a right hemisphere stroke occurred in a 62-year-old male. Dysfluency was characterized by pronounced word and phrase reiterations, and sound and syllable reiterations to a lesser degree. Spontaneous speech was ... Full text Link to item Cite

Ocular bobbing in metabolic encephalopathy: clinical, pathologic, and electrophysiologic study.

Journal article Neurology · September 1982 A patient with atypical ocular bobbing resulting from metabolic encephalopathy is described. Neurologic examination showed no signs of brainstem dysfunction, and postmortem examination failed to disclose any changes in sites associated with ocular bobbing ... Full text Link to item Cite

Peroneal palsy in stroke patients.

Journal article Postgrad Med · June 1982 Full text Link to item Cite

Managing the patient with dementia.

Journal article Postgrad Med · May 1982 Dementia due to degenerative changes or to some chronic disorders involves gradual loss of function, and it is important that the patient, spouse, and family know what to expect. Counseling from the physician at an early stage can help the patient maintain ... Full text Link to item Cite

Effort headache in runners.

Journal article Headache · May 1982 Full text Link to item Cite

Familial benign intracranial hypertension and depression.

Journal article Can J Neurol Sci · February 1982 Two sisters developed benign intracranial hypertension (BIH) two weeks following the resolution of a major depressive episode. The association of BIH and a major affective disorder in genetically related individuals has not been previously reported to our ... Full text Link to item Cite

Multiple mononeuropathy or mononeuritis multiplex in diabetics?

Journal article Acta Diabetologica Latina · January 1, 1982 Separation of two distinct clinical entities occurring in diabetes mellitus seems important. Mononeuritis multiplex occurs with a worsening of the diffuse neuropathy and seems unrelated to control. Multiple mononeuropathy is likely related to entrapment wh ... Full text Cite

International patterns of mortality from multiple sclerosis

Journal article Neuroepidemiology · January 1, 1982 Full text Cite

TIA, stroke, and the bicuspid aortic valve.

Journal article Neurology · December 1981 Congenital bicuspid aortic valve, one of the most common congenital heart abnormalities, may become infected, may calcify, and may cause progressive stenosis or progressive insufficiency. While no previous reports suggested cerebral emboli in the absence o ... Full text Link to item Cite

Diabetic thoracoabdominal neuropathy.

Journal article Ann Neurol · November 1981 Full text Link to item Cite

Familial Bell's palsy.

Journal article Ear Nose Throat J · November 1981 Link to item Cite

Peroneal palsy in patients with dementia.

Journal article N C Med J · October 1981 Link to item Cite

Mental neuropathy from systemic cancer.

Journal article Neurology · October 1981 Nineteen patients with mental neuropathy secondary to systemic cancer are described. In nine patients, the numb chin was the presenting symptom of a neoplasm. Nine patients had lymphoreticular malignancies, and the others had a variety of solid tumors. Rad ... Full text Link to item Cite

"Hunkering"; and peroneal palsy.

Journal article Muscle and Nerve · September 1, 1981 Cite

Arsenic neuropathy.

Journal article Neurology · August 1981 Full text Link to item Cite

Soft neurologic signs.

Journal article Postgrad Med · July 1981 Full text Link to item Cite

North Carolina medical curiosities. The two-headed girl.

Journal article North Carolina Medical Journal · May 1, 1981 Cite

The "jerks": mass hysteria or epilepsy?

Journal article South Med J · May 1981 Hysterical "epidemics" of "epilepsy" are well known in Eastern and Western cultures. A unique situation in the United States in the 19th and 20th centuries was the American religious movement, the setting in which "the jerks" occurred. Descriptions of vari ... Link to item Cite

North Carolina medical curiosities.

Journal article N C Med J · April 1981 Link to item Cite

The heaviest man on record.

Journal article N C Med J · March 1981 Link to item Cite

Neurological manifestations of malignancies.

Journal article Mil Med · March 1981 Link to item Cite

CT evaluation of lumbosacral plexus disorders.

Journal article Postgrad Med · February 1981 Full text Link to item Cite

Arsenic poisoning.

Journal article Southern Medical Journal · January 1, 1981 Cite

Gonyalgia paresthetica.

Journal article Muscle and Nerve · January 1, 1981 Cite

"Hunkering"; and peroneal palsy.

Journal article Muscle Nerve · 1981 Full text Link to item Cite

Intermittent claudication: importance of etiologic differentiation as an aid in selecting therapy.

Journal article J Am Geriatr Soc · January 1981 Intermittent claudication in the lower extremities is often manifested in either of two treatable forms, i.e., neurogenic or vascular. A thorough history and examination are necessary to distinguish between these two types. The main differential point is w ... Full text Link to item Cite

Arsenic poisoning.

Journal article South Med J · January 1981 Full text Link to item Cite

Gonyalgia paresthetica.

Journal article Muscle Nerve · 1981 Full text Link to item Cite

Nontraumatic mononeuropathies: a review.

Journal article Mil Med · January 1981 Link to item Cite

Lithium carbonate in pseudobulbar palsy.

Journal article Ann Neurol · January 1981 Full text Link to item Cite

Cylindroma causing Garcin's syndrome.

Journal article Arch Neurol · December 1980 Full text Link to item Cite

Pseudoseizures: recognition and treatment.

Journal article Psychosomatics · December 1980 Full text Link to item Cite

Joseph Bell, MD, FRCS--Mr. Sherlock Holmes?

Journal article South Med J · December 1980 Full text Link to item Cite

Evaluating loss of consciousness in the elderly.

Journal article J Am Geriatr Soc · November 1980 In the case of an elderly patient with transient loss of consciousness, the chief differential diagnosis is syncope versus seizure. The most helpful diagnostic aid is a thorough history obtained from both the patient and an observer. The tentative diagnosi ... Full text Link to item Cite

Carpal tunnel syndrome in porphyria.

Journal article Lancet · October 11, 1980 Cite

Carpal tunnel syndrome in porphyria.

Journal article Lancet · October 11, 1980 Full text Link to item Cite

Managing the patient with peripheral neuropathy.

Journal article Postgrad Med · October 1980 Peripheral neuropathy may be a minor, even unrecognized, clinical problem, or it may be severe and virtually disabling. As in any chronic disorder, the physician's role is to look for treatable disease and to teach patients about the symptoms and natural h ... Full text Link to item Cite

Drug error in anticonvulsant therapy.

Journal article Ann Neurol · October 1980 Full text Link to item Cite

Dr. Samuel Mudd: justice at last.

Journal article South Med J · October 1980 Full text Link to item Cite

Pseudoseizures in the military.

Journal article Mil Med · September 1980 Link to item Cite

Managing the patient with Parkinson's disease.

Journal article Postgrad Med · September 1980 When patients have a clear understanding of the etiology and pathophysiology of Parkinson's disease, management is easier for the physician and the patient is better able to cope with the disease. Patients also should be made aware of the proper use of ant ... Full text Link to item Cite

Facial synkinesis.

Journal article Ear Nose Throat J · July 1980 Link to item Cite

Neuropsychiatric manifestations of porphyria.

Journal article J Clin Psychiatry · June 1980 Porphyria is a rare disorder in medical practice; however, its clinical manifestations are primarily neuropsychological. This paper reviews this entity regarding diagnosis, treatment, metabolic, and genetic features. ... Link to item Cite

Compression injury of the sciatic nerve during a prolonged surgical procedure in a diabetic patient.

Journal article J Am Geriatr Soc · April 1980 Patients with diabetes mellitus and an underlying mixed axonal and demyelinating polyneuropathy are particularly prone to compression neuropathies with consequent axonal degeneration and a poor prognosis for recovery. This hazard should be taken into accou ... Full text Link to item Cite

Meralgia paresthetica secondary to trauma of bone graft.

Journal article J Trauma · April 1980 Many causes of meralgia paresthetica (neuropathy of lateral cutaneous nerve of thigh) have been suggested. This is a case of a 42-year-old man who developed sensory loss and dysesthesia in the anterolateral thigh following an incision for pelvic bone graft ... Link to item Cite

Tricyclic Antidepressants for Peripheral Neuropathy

Journal article JAMA the Journal of the American Medical Association · March 21, 1980 Full text Cite

Intercostal neuralgia of pregnancy.

Journal article JAMA · February 22, 1980 Link to item Cite

Managing the epileptic patient.

Journal article Postgrad Med · February 1980 A review of hospital charts revealed that only 3 (7.5%) of 40 inpatients with a diagnosis of epilepsy had received counseling about the disorder, its treatment, and its social ramifications. Although it is often neglected--as indicated by this small sample ... Full text Link to item Cite

Migraine.

Journal article South Med J · February 1980 Full text Link to item Cite

Diabetic truncal mononeuropathy: electromyographic evaluation.

Journal article Acta Diabetol Lat · 1980 Fifteen diabetic subjects wih thoracic radiculopathy were studied wih paraspinal electromyography. The majority were elderly, mature onset diabetics presenting with unilateral hyperesthesia in a thoracic radicular pattern. None was under adequate control a ... Full text Link to item Cite

Fibromuscular dysplasia of the carotid artery: A cause of congenital Horner's syndrome?

Journal article Annals of Ophthalmology · January 1, 1980 A 42-year-old female with amaurosis fugax in the right eye and an ipsilateral postganglionic congenital Horner's syndrome was found to have fibromuscular dysplasia of the right internal carotid artery on arteriography. The proposed etiological mechanisms o ... Cite

Sjögren's syndrome and mononeuritis multiplex.

Journal article Ann Intern Med · January 1980 Full text Link to item Cite

Neuropathy of the hand.

Journal article JAMA · November 23, 1979 Link to item Cite

Familial carpal tunnel syndrome.

Journal article Arch Neurol · November 1979 Full text Link to item Cite

Carpal tunnel syndrome in hepatic disease.

Journal article South Med J · August 1979 Full text Link to item Cite

Localized pruritus-notalgia paresthetica.

Journal article Arch Dermatol · August 1979 Notalgia paresthetica, possibly an isolated sensory neuropathy involving the posterior primary rami of thoracic nerves T2 through T6, and appearing as pruritus of the back, is apt to be encountered by both dermatologists and neurologists. Two cases illustr ... Link to item Cite

Multiple sensory neuritis: case report.

Journal article Mil Med · August 1979 Link to item Cite

Unilateral asterixis: motor integrative dysfunction in focal vascular disease.

Journal article Neurology · August 1979 In three patients we found unilateral asterixis in limbs contralateral to a discrete lesion adjacent to the internal capsule. Etiology was vascular in each, with no metabolic or toxic disturbance. Unilateral asterixis bespeaks focal disease arising from le ... Full text Link to item Cite

Neuropathies of pregnancy.

Journal article Obstet Gynecol Surv · July 1979 Full text Link to item Cite

Cerebral vasculitis.

Journal article Arch Neurol · May 1979 Full text Link to item Cite

Mononeuropathy in diabetes mellitus: a phenomenon easily overlooked.

Journal article Postgrad Med · May 1979 In patients with diabetes, a carefully taken history and meticulously performed neurologic examination enable the clinician to separate superimposed mononeuropathy from more generalized symmetric polyneuropathy. Recognition of mononeuroparhy is important, ... Full text Link to item Cite

Tapia's syndrome. The erratic evolution of an eponym.

Journal article Arch Neurol · May 1979 The syndrome first described in 1904 by the Spanish otolaryngologist, Antonio Garcia Tapia, has been variously interpreted by subsequent authors such that there is little current agreement as to the site of the lesion responsible for the condition or the s ... Full text Link to item Cite

Notalgia paresthetica.

Journal article JAMA · April 6, 1979 Full text Link to item Cite

Lid retraction test.

Journal article J Clin Psychiatry · March 1979 Link to item Cite

Pelvic mass presenting as meralgia paresthetica.

Journal article Obstet Gynecol · February 1979 A 40-year-old woman presented to her gynecologist with an apparent unilateral neuropathy of the lateral cutaneous femoral nerve of the thigh (meralgia paresthetica). On examination, the sensory disturbance extended outside the usual distribution of the lat ... Link to item Cite

Unilateral asterixis.

Journal article JAMA · January 12, 1979 Full text Link to item Cite

Notalgia paresthetica

Journal article Neurology · January 1, 1979 Full text Cite

Handcuff-related cheiralgia paresthetica

Journal article Neurology · January 1, 1979 Full text Cite

Notalgia paresthetica.

Journal article Journal of the American Medical Association · 1979 Full text Cite

Unilateral asterixis.

Journal article Journal of the American Medical Association · 1979 Full text Cite

Penicillin neuropathy.

Journal article Anesth Analg · 1979 Link to item Cite

Handcuffs and cheiralgia paresthetica.

Journal article Neurology · December 1978 Cheiralgia paresthetica has been reported in the past, but the exact etiology is unknown. We present two cases that occurred secondary to handcuff placement. ... Full text Link to item Cite

Cause and effect in "alcoholic tremor".

Journal article Am J Psychiatry · December 1978 Full text Link to item Cite

Notalgia paresthetica.

Journal article Neurology · December 1978 Notalgia paresthetica was described by Astwazaturow in 1934. We have seen six cases in the past year, suggesting that it is not rare. This sensory neuritis affects the posterior rami of several spinal nerves (arising from thoracic segments T2 to T6), causi ... Full text Link to item Cite

Leprosy: biblical opprobrium?

Journal article South Med J · October 1978 Link to item Cite

Sports-car palsy.

Journal article N Engl J Med · August 24, 1978 Full text Link to item Cite

Menstrual meralgia.

Journal article Arch Neurol · August 1978 Full text Link to item Cite

Meralgia paraesthetica in a child.

Journal article J Pediatr · August 1978 Full text Link to item Cite

Acroparesthesias in pregnancy.

Journal article South Med J · July 1978 Full text Link to item Cite

Sciatic neuropathy with giant-cell arteritis.

Journal article N Engl J Med · April 20, 1978 Full text Link to item Cite

Digitalgia parethetica in the foot.

Journal article JAMA · April 3, 1978 Full text Link to item Cite

Peroneal palsy in depression.

Journal article J Clin Psychiatry · April 1978 In the psychiatric patient cross leg palsy can be a subtle but significant problem. The patient, rendered inactive by a depressive illness, who has lost weight, whose activities include much sitting, or who has a disease that may predispose to a neuropathy ... Link to item Cite

Carpal tunnel syndrome in pregnancy.

Journal article Obstet Gynecol Surv · March 1978 The signs and symptoms of carpal tunnel syndrome in pregnant patients are outlined and the diagnostic methods are reviewed. Carpal tunnel syndrome that occurs during pregnancy almost invariably abates postpartum. Due to the benign course and excellent prog ... Full text Link to item Cite

Meralgia paraesthetica in physicians.

Journal article JAMA · February 13, 1978 Full text Link to item Cite

Cluneal neuropathy.

Journal article Anesth Analg · 1978 Full text Link to item Cite

Median neuropathy affecting the first dorsal interosseous muscle.

Journal article Muscle Nerve · 1978 This case report documents the clinical entity of median nerve supply to the first dorsal interosseous muscle, which occurs in 3% of individuals. This must be remembered in evaluation of neuropathy involving the hand muscles. ... Full text Link to item Cite

Meralgia paraesthetica in physicians.

Journal article Journal of the American Medical Association · 1978 Full text Cite

Neuropathy in joggers.

Journal article Am J Sports Med · 1978 We have reported upon three different mononeuropathies that we believe were directly attributable to jogging. At this time it is presumed that this complication is not common, but as jogging increases as a routine form of exercise for the general populace ... Full text Link to item Cite

Cheiralgia paresthetica in diabetes mellitus.

Journal article Diabetes Care · 1978 Cheiralgia paresthetica is a sensory mononeuropathy of the superficial ramus of the radial nerve. A case is presented here in a patient with diabetes mellitus. ... Full text Link to item Cite

Digitalgia paresthetica in the foot

Journal article Journal of the American Medical Association · 1978 Full text Cite

Migraine during pregnancy.

Journal article Obstet Gynecol Surv · November 1977 Full text Link to item Cite

Meralgia paraesthetica. An unusual case.

Journal article JAMA · March 14, 1977 Link to item Cite

A review of rectal biopsy.

Journal article South Med J · March 1970 Full text Link to item Cite