Scholars@Duke

• Background
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  Education, Training, & Certifications

  • Ph.D., University of Michigan, Ann Arbor 2005
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  Previous Appointments & Affiliations

  • Assistant Professor of the Practice of Medical Education in the Department of Cell Biology, Cell Biology, Basic Science Departments 2020 - 2022
  • Assistant Professor of the Practice of Medical Education in the Department of Cell Biology, Cell Biology, Basic Science Departments 2019 - 2021
  • Assistant Professor of the Practice of Medical Education in the Department of Cell Biology, Cell Biology, Basic Science Departments 2018 - 2020
  • Assistant Professor of the Practice of Medical Education in the Department of Cell Biology, Cell Biology, Basic Science Departments 2017 - 2019
  • Assistant Professor of the Practice of Medical Education in the Department of Cell Biology, Cell Biology, Basic Science Departments 2016 - 2018
  • Assistant Professor of the Practice of Medical Education in the Department of Cell Biology, Cell Biology, Basic Science Departments 2015 - 2017
  • Assistant Professor of the Practice of Medical Education in the Department of Cell Biology, Cell Biology, Basic Science Departments 2014 - 2016
  • Assistant Professor of the Practice of Medical Education in the Department of Cell Biology, Cell Biology, Basic Science Departments 2013 - 2015
  • Assistant Professor of the Practice of Medical Education in the Department of Cell Biology, Cell Biology, Basic Science Departments 2012 - 2014
  • Assistant Professor of the Practice of Medical Education in the Department of Cell Biology, Cell Biology, Basic Science Departments 2011 - 2013
  • Assistant Professor of the Practice of Medical Education in the Department of Cell Biology, Cell Biology, Basic Science Departments 2010 - 2012
  • Assistant Professor of the Practice of Medical Education in the Department of Cell Biology, Cell Biology, Basic Science Departments 2010 - 2011
• 

  Leadership & Clinical Positions at Duke

  • Assistant Dean for Biomedical Sciences Education, Duke University School of Medicine, 2013 to present:
    

    • maintain and coordinate appropriate biomedical sciences curriculum

    • faculty development oversight

    • introduce curricular changes and innovations as needed

    • facilitate communication among course directors in the first year medical curriculum

    • coordinate activities related to LCME review of the biomedical sciences curriculum.
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  Academic Positions Outside Duke

  • Lecturer, University of Michigan Medical School. 2005 - 2021
• Recognition
• 

  Awards & Honors

  • Master Clinician/Teacher Award. Duke University School of Medicine. 2021
  • Golden Apple For Preclinical Faculty. Duke University School of Medicine Davison Council. 2019
  • Golden Apple For Preclinical Faculty. Duke University School of Medicine Davison Council. 2015
  • Fellow. Duke Academy for Health Professions Education and Academic Development (AHEAD). 2014
  • Golden Apple For Preclinical Faculty. Duke University School of Medicine Davison Council. 2013
  • Golden Apple For Preclinical Faculty. Duke University School of Medicine Davison Council. 2012
  • Golden Apple For Preclinical Faculty. Duke University School of Medicine Davison Council. 2011
  • Kaiser Permanente Award for Excellence in Pre-clinical Teaching. Univeristy of Michigan Medical School. 2010
• Expertise
• 

  Subject Headings

  • Aorta
  • Basic Helix-Loop-Helix Transcription Factors
  • Biological Markers
  • Brain-Derived Neurotrophic Factor
  • Cell Differentiation
  • Cell Lineage
  • Cell Proliferation
  • Cells, Cultured
  • Chick Embryo
  • Cochlear Nerve
  • Coronary Vessels
  • Deafness
  • Doxycycline
  • Embryo, Mammalian
  • Embryonic Stem Cells
  • Flow Cytometry
  • Gene Expression
  • Gene Expression Profiling
  • Gene Transfer Techniques
  • Genes, Reporter
  • Genetic Techniques
  • Glial Cell Line-Derived Neurotrophic Factor
  • Glutamic Acid
  • Green Fluorescent Proteins
  • Growth Substances
  • Guinea Pigs
  • Humans
  • Immunohistochemistry
  • Luminescent Proteins
  • Mice
  • Microscopy, Electron
  • Models, Genetic
  • Molecular Sequence Data
  • Neovascularization, Physiologic
  • Nerve Regeneration
  • Neural Stem Cells
  • Neurodegenerative Diseases
  • Neurogenesis
  • Neurons
  • Octamer Transcription Factor-3
  • Plasmids
  • Pluripotent Stem Cells
  • Promoter Regions, Genetic
  • RNA Interference
  • RNA Polymerase III
  • Reverse Transcriptase Polymerase Chain Reaction
  • Signal Transduction
  • Spinal Cord Diseases
  • Stem Cell Transplantation
  • Stem Cells
  • Tissue Engineering
  • Transcription Factors
  • Transfection
  • Transplantation, Heterologous
• Research
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  External Relationships

  • Pfizer Inc.
• Publications & Artistic Works
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  Selected Publications

  • Academic Articles

    • Velkey, J. M., and K. S. O’Shea. “Expression of Neurogenin 1 in Mouse Embryonic Stem Cells Directs the Differentiation of Neuronal Precursors and Identifies Unique Patterns of Down-stream Gene Expression.” Dev Dyn 242, no. 5 (May 2013): C1. https://doi.org/10.1002/dvdy.23974.
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    • Velkey, J Matthew, and K Sue O’Shea. “Expression of Neurogenin 1 in mouse embryonic stem cells directs the differentiation of neuronal precursors and identifies unique patterns of down-stream gene expression.” Dev Dyn 242, no. 3 (March 2013): 230–53. https://doi.org/10.1002/dvdy.23920.
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    • Purcell, Erin K., Amy Yang, Liqian Liu, J Matthew Velkey, Marti M. Morales, and R Keith Duncan. “BDNF profoundly and specifically increases KCNQ4 expression in neurons derived from embryonic stem cells.” Stem Cell Res 10, no. 1 (January 2013): 29–35. https://doi.org/10.1016/j.scr.2012.08.005.
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    • Purcell, Erin K., Youssef Naim, Amy Yang, Michelle K. Leach, J Matthew Velkey, R Keith Duncan, and Joseph M. Corey. “Combining topographical and genetic cues to promote neuronal fate specification in stem cells.” Biomacromolecules 13, no. 11 (November 12, 2012): 3427–38. https://doi.org/10.1021/bm301220k.
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    • Hill, Gerhard W., Erin K. Purcell, Liqian Liu, John Matthew Velkey, Richard A. Altschuler, and Robert Keith Duncan. “Netrin-1-mediated axon guidance in mouse embryonic stem cells overexpressing neurogenin-1.” Stem Cells Dev 21, no. 15 (October 10, 2012): 2827–37. https://doi.org/10.1089/scd.2011.0437.
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    • Lunn, J Simon, Crystal Pacut, Emily Stern, Stacey A. Sakowski, J Matthew Velkey, Sue O’Shea, and Eva L. Feldman. “Intraspinal transplantation of neurogenin-expressing stem cells generates spinal cord neural progenitors.” Neurobiol Dis 46, no. 1 (April 2012): 59–68. https://doi.org/10.1016/j.nbd.2011.12.044.
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    • Reyes, Jeannie H., K Sue O’Shea, Noel L. Wys, J Matthew Velkey, Diane M. Prieskorn, Karolina Wesolowski, Josef M. Miller, and Richard A. Altschuler. “Glutamatergic neuronal differentiation of mouse embryonic stem cells after transient expression of neurogenin 1 and treatment with BDNF and GDNF: in vitro and in vivo studies.” J Neurosci 28, no. 48 (November 26, 2008): 12622–31. https://doi.org/10.1523/JNEUROSCI.0563-08.2008.
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    • Rodriguez, Ryan T., J Matthew Velkey, Carolyn Lutzko, Rina Seerke, Donald B. Kohn, K Sue O’Shea, and Meri T. Firpo. “Manipulation of OCT4 levels in human embryonic stem cells results in induction of differential cell types.” Exp Biol Med (Maywood) 232, no. 10 (November 2007): 1368–80. https://doi.org/10.3181/0703-RM-63.
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    • Velkey, J Matthew, Nicole A. Slawny, Theresa E. Gratsch, and K Sue O’Shea. “Gene silencing using RNA interference in embryonic stem cells.” Methods Mol Biol 329 (2006): 233–61. https://doi.org/10.1385/1-59745-037-5:233.
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    • Velkey, J Matthew, and K Sue O’Shea. “Oct4 RNA interference induces trophectoderm differentiation in mouse embryonic stem cells.” Genesis 37, no. 1 (September 2003): 18–24. https://doi.org/10.1002/gene.10218.
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    • Bernanke, David H., and J Matthew Velkey. “Development of the coronary blood supply: changing concepts and current ideas.” Anat Rec 269, no. 4 (August 15, 2002): 198–208. https://doi.org/10.1002/ar.10139.
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    • Velkey, J. M., and D. H. Bernanke. “Apoptosis during coronary artery orifice development in the chick embryo.” Anat Rec 262, no. 3 (March 1, 2001): 310–17. https://doi.org/10.1002/1097-0185(20010301)262:3<310::AID-AR1040>3.0.CO;2-Y.
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    • Velkey, J. M., J. P. Naftel, M. D. Ard, T. P. Ma, and G. A. Hoskins. “Development of a digital electron micrograph atlas for medical histology education.” Faseb Journal 14, no. 4 (March 15, 2000): A308–A308.
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    • Velkey, J. M., and D. K. Bernanke. “Developing coronary arteries in the chick acquire patent connections to the aorta by a mechanism involving apoptosis.” Faseb Journal 14, no. 4 (March 15, 2000): A21–A21.
       Link to Item

  • Conference Papers

    • Taylor, Andrea B., J Matthew Velkey, Janet Gwyer, and Leonard E. White. “Body and Brain: Anatomy of team-based learning in a preclinical science course.” In American Journal of Physical Anthropology, 156:301–301. WILEY-BLACKWELL, 2015.
       Link to Item
    • Velkey, J. M., and K. S. O’Shea. “Neuronal differentiation and subtype specification following inducible expression of neurogenin-1 in mouse embryonic stem cells.” In Faseb Journal, 19:A231–A231. FEDERATION AMER SOC EXP BIOL, 2005.
       Link to Item
    • Velkey, J. M., and K. S. O’Shea. “Knockdown of Oct3/4 expression in mouse embryonic stem cells by RNA interference.” In Faseb Journal, 17:A775–76. FEDERATION AMER SOC EXP BIOL, 2003.
       Link to Item
• Teaching & Mentoring
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  Recent Courses

  • INTERDIS 113B: Foundations of Patient Care 2 2022
  • PATHASST 102: Body and Disease 2022
  • INTERDIS 102B: Body and Disease 2021
  • PATHASST 102: Body and Disease 2021
  • HLTHSCI 503: Organ Systems 2020
  • INTERDIS 102B: Body and Disease 2020
  • PATHASST 102: Body and Disease 2020

Some information on this profile has been compiled automatically from Duke databases and external sources. (Our About page explains how this works.) If you see a problem with the information, please write to Scholars@Duke and let us know. We will reply promptly.