John Matthew Velkey | Scholars@Duke

John Matthew Velkey
Assistant Professor of the Practice of Medical Education in the Department of Cell Biology

Current Appointments & Affiliations

Assistant Professor of the Practice of Medical Education in the Department of Cell Biology, Cell Biology, Basic Science Departments 2010

Contact Information

10 Searle Drive, 321 Seeley G. Mudd Medical Library Bldg, Durham, NC 27710
Duke Box 3899, Durham, NC 27710
matt.velkey@duke.edu

Background
Education, Training, & Certifications
- Ph.D., University of Michigan, Ann Arbor 2005
Leadership & Clinical Positions at Duke
- Assistant Dean for Basic Science Education, Duke University School of Medicine
Academic Positions Outside Duke
- Lecturer, University of Michigan Medical School. 2005 - 2019
Recognition
Awards & Honors
Expertise
Subject Headings
Research
External Relationships
- Pfizer Inc.
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Velkey, J. M., and K. S. O’Shea. “Expression of Neurogenin 1 in Mouse Embryonic Stem Cells Directs the Differentiation of Neuronal Precursors and Identifies Unique Patterns of Down-stream Gene Expression.” Dev Dyn 242, no. 5 (May 2013): C1. https://doi.org/10.1002/dvdy.23974.
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  - Velkey, J Matthew, and K Sue O’Shea. “Expression of Neurogenin 1 in mouse embryonic stem cells directs the differentiation of neuronal precursors and identifies unique patterns of down-stream gene expression.” Dev Dyn 242, no. 3 (March 2013): 230–53. https://doi.org/10.1002/dvdy.23920.
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  - Purcell, Erin K., Amy Yang, Liqian Liu, J Matthew Velkey, Marti M. Morales, and R Keith Duncan. “BDNF profoundly and specifically increases KCNQ4 expression in neurons derived from embryonic stem cells.” Stem Cell Res 10, no. 1 (January 2013): 29–35. https://doi.org/10.1016/j.scr.2012.08.005.
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  - Purcell, Erin K., Youssef Naim, Amy Yang, Michelle K. Leach, J Matthew Velkey, R Keith Duncan, and Joseph M. Corey. “Combining topographical and genetic cues to promote neuronal fate specification in stem cells.” Biomacromolecules 13, no. 11 (November 12, 2012): 3427–38. https://doi.org/10.1021/bm301220k.
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  - Hill, Gerhard W., Erin K. Purcell, Liqian Liu, John Matthew Velkey, Richard A. Altschuler, and Robert Keith Duncan. “Netrin-1-mediated axon guidance in mouse embryonic stem cells overexpressing neurogenin-1.” Stem Cells Dev 21, no. 15 (October 10, 2012): 2827–37. https://doi.org/10.1089/scd.2011.0437.
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  - Lunn, J Simon, Crystal Pacut, Emily Stern, Stacey A. Sakowski, J Matthew Velkey, Sue O’Shea, and Eva L. Feldman. “Intraspinal transplantation of neurogenin-expressing stem cells generates spinal cord neural progenitors.” Neurobiol Dis 46, no. 1 (April 2012): 59–68. https://doi.org/10.1016/j.nbd.2011.12.044.
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  - Reyes, Jeannie H., K Sue O’Shea, Noel L. Wys, J Matthew Velkey, Diane M. Prieskorn, Karolina Wesolowski, Josef M. Miller, and Richard A. Altschuler. “Glutamatergic neuronal differentiation of mouse embryonic stem cells after transient expression of neurogenin 1 and treatment with BDNF and GDNF: in vitro and in vivo studies.” J Neurosci 28, no. 48 (November 26, 2008): 12622–31. https://doi.org/10.1523/JNEUROSCI.0563-08.2008.
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  - Rodriguez, Ryan T., J Matthew Velkey, Carolyn Lutzko, Rina Seerke, Donald B. Kohn, K Sue O’Shea, and Meri T. Firpo. “Manipulation of OCT4 levels in human embryonic stem cells results in induction of differential cell types.” Exp Biol Med (Maywood) 232, no. 10 (November 2007): 1368–80. https://doi.org/10.3181/0703-RM-63.
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  - Velkey, J Matthew, Nicole A. Slawny, Theresa E. Gratsch, and K Sue O’Shea. “Gene silencing using RNA interference in embryonic stem cells.” Methods Mol Biol 329 (2006): 233–61. https://doi.org/10.1385/1-59745-037-5:233.
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  - Velkey, J Matthew, and K Sue O’Shea. “Oct4 RNA interference induces trophectoderm differentiation in mouse embryonic stem cells.” Genesis 37, no. 1 (September 2003): 18–24. https://doi.org/10.1002/gene.10218.
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  - Bernanke, David H., and J Matthew Velkey. “Development of the coronary blood supply: changing concepts and current ideas.” Anat Rec 269, no. 4 (August 15, 2002): 198–208. https://doi.org/10.1002/ar.10139.
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  - Velkey, J. M., and D. H. Bernanke. “Apoptosis during coronary artery orifice development in the chick embryo.” Anat Rec 262, no. 3 (March 1, 2001): 310–17. https://doi.org/10.1002/1097-0185(20010301)262:3<310::AID-AR1040>3.0.CO;2-Y.
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  - Velkey, J. M., J. P. Naftel, M. D. Ard, T. P. Ma, and G. A. Hoskins. “Development of a digital electron micrograph atlas for medical histology education.” Faseb Journal 14, no. 4 (March 15, 2000): A308–A308.
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  - Velkey, J. M., and D. K. Bernanke. “Developing coronary arteries in the chick acquire patent connections to the aorta by a mechanism involving apoptosis.” Faseb Journal 14, no. 4 (March 15, 2000): A21–A21.
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- Conference Papers
  - Taylor, Andrea B., J Matthew Velkey, Janet Gwyer, and Leonard E. White. “Body and Brain: Anatomy of team-based learning in a preclinical science course.” In American Journal of Physical Anthropology, 156:301–301. WILEY-BLACKWELL, 2015.
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  - Velkey, J. M., and K. S. O’Shea. “Neuronal differentiation and subtype specification following inducible expression of neurogenin-1 in mouse embryonic stem cells.” In Faseb Journal, 19:A231–A231. FEDERATION AMER SOC EXP BIOL, 2005.
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  - Velkey, J. M., and K. S. O’Shea. “Knockdown of Oct3/4 expression in mouse embryonic stem cells by RNA interference.” In Faseb Journal, 17:A775–76. FEDERATION AMER SOC EXP BIOL, 2003.
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Teaching & Mentoring
Recent Courses
- HLTHSCI 503: Organ Systems 2020
- INTERDIS 102B: Body and Disease 2020
- PATHASST 102: Body and Disease 2020

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Education, Training, & Certifications

Leadership & Clinical Positions at Duke

Academic Positions Outside Duke

Awards & Honors

Subject Headings

External Relationships

Selected Publications

Academic Articles

Conference Papers

Recent Courses