Megan Elizabeth Bowles Clowse

Journal article J Rheumatol · June 2011 Featured Publication OBJECTIVE: The importance of low complement and anti-dsDNA during pregnancy in patients with systemic lupus erythematosus (SLE) is poorly defined. We investigated the effect of these laboratory tests and clinical SLE activity on pregnancy outcomes. METHODS ... Full text Link to item Cite

Late ovarian hyperstimulation syndrome after controlled ovarian stimulation in a woman with systemic lupus erythematosus and lupus nephritis.

Journal article Fertil Steril · April 2011 Featured Publication OBJECTIVE: To report a case of late ovarian hyperstimulation syndrome (OHSS) in a woman with lupus nephritis undergoing controlled ovarian stimulation and in vitro fertilization (IVF) with subsequent transfer into a gestational surrogate. DESIGN: A case re ... Full text Link to item Cite

The use of anti-TNFα medications for rheumatologic disease in pregnancy.

Journal article Int J Womens Health · August 9, 2010 Featured Publication Anti-TNFα medications have led to vast improvements in the treatment of inflammatory conditions, including rheumatoid arthritis and Crohn's disease. As these diseases often afflict women in their reproductive years, the safety of these drugs during pregnan ... Full text Link to item Cite

Managing contraception and pregnancy in the rheumatologic diseases.

Journal article Best Pract Res Clin Rheumatol · June 2010 Featured Publication Most pregnancies in women with rheumatologic disease will result in the delivery of a healthy baby. Pregnancy can be particularly risky in women with active disease or on teratogenic medications, making contraception an important issue for these women. All ... Full text Link to item Cite

The management of rheumatic diseases in pregnancy.

Journal article Scand J Rheumatol · March 2010 Featured Publication Pregnancy can create a challenge for physicians caring for women with rheumatic diseases. For many women with rheumatoid arthritis (RA), pregnancy can provide a reprieve from long-term joint pain and inflammation, but others will not experience remission a ... Full text Link to item Cite

A national study of the complications of lupus in pregnancy.

Journal article Am J Obstet Gynecol · August 2008 Featured Publication OBJECTIVE: This study was undertaken to determine the risk of rare complications during pregnancy for women with systemic lupus erythematosus. STUDY DESIGN: By using the Nationwide Inpatient Sample from 2000-2003, we compared maternal and pregnancy complic ... Full text Link to item Cite

Lupus activity in pregnancy.

Journal article Rheum Dis Clin North Am · May 2007 Featured Publication Pregnancy in a woman with systemic lupus erythematosus (SLE) can be complicated by both lupus activity and pregnancy mishaps. The majority of recent studies found an increase in lupus activity during pregnancy, perhaps exacerbated by hormonal shifts requir ... Full text Link to item Cite

Hydroxychloroquine in lupus pregnancy.

Journal article Arthritis Rheum · November 2006 Featured Publication OBJECTIVE: Hydroxychloroquine (HCQ) is often needed to manage disease activity in systemic lupus erythematosus (SLE) during pregnancy. The purpose of this study was to examine lupus activity and pregnancy outcomes in women with SLE treated or not treated w ... Full text Link to item Cite

Early risk factors for pregnancy loss in lupus.

Journal article Obstet Gynecol · February 2006 Featured Publication OBJECTIVE: To identify early risk factors for pregnancy loss in lupus pregnancies. METHODS: We conducted a cohort study of all pregnancies seen in the first trimester in lupus patients followed from 1987 to 2002 at the Hopkins Lupus Center. At each visit, ... Full text Link to item Cite

The impact of increased lupus activity on obstetric outcomes.

Journal article Arthritis Rheum · February 2005 Featured Publication OBJECTIVE: Systemic lupus erythematosus is associated with multiple adverse pregnancy outcomes. We examined the impact of disease activity on spontaneous abortions, perinatal mortality, preterm delivery, and birth weight. METHODS: The study was designed to ... Full text Link to item Cite

Cyclophosphamide for lupus during pregnancy.

Journal article Lupus · 2005 Featured Publication Severe systemic lupus erythematosus often requires the use of cyclophosphamide in women of reproductive age. As cyclophosphamide is generally avoided during pregnancy because of its teratogenic risk, its impact on fetal survival is poorly understood. This ... Full text Link to item Cite

Digital necrosis related to carboplatin and gemcitabine therapy in systemic sclerosis.

Journal article J Rheumatol · June 2003 Featured Publication We present a woman with scleroderma who developed multiple ischemic digits after chemotherapy for lung cancer. The ischemia started during treatment with carboplatin and gemcitabine and required amputation of the affected digits. A review of the literature ... Link to item Cite