Megan Elizabeth Bowles Clowse

Journal article Arthritis Care Res (Hoboken) · July 13, 2026 OBJECTIVE: Appropriately addressing reproductive health requires that a provider know a patient's contraceptive method and interest in pregnancy; this information is often missing from rheumatology visit documentation. METHODS: A Learning Collaborative (LC ... Full text Link to item Cite

Differences in Self-Reported Medication Nonadherence and Its Drivers in Young Adults Versus Older Adults With Systemic Lupus Erythematosus.

Journal article J Rheumatol · July 1, 2026 OBJECTIVE: Medication adherence poses a challenge for young patients with systemic lupus erythematosus (SLE), who experience more active disease and damage than their older counterparts. This study aimed to quantify the rate of medication nonadherence by a ... Full text Link to item Cite

Efficacy and safety of the CD40 ligand inhibitor dapirolizumab pegol in systemic lupus erythematosus (PHOENYCS GO): a randomised, double-blind, placebo-controlled, phase 3 trial.

Journal article Lancet · June 6, 2026 BACKGROUND: Dapirolizumab pegol is a novel CD40 ligand inhibitor. In this phase 3 trial, we aimed to evaluate the efficacy and safety of dapirolizumab pegol in patients with systemic lupus erythematosus (SLE). METHODS: PHOENYCS GO was a 48-week, randomised ... Full text Link to item Cite

Pharmacokinetics of Certolizumab Pegol in Pregnancy: Results from the Open-Label CHERISH Study.

Journal article Rheumatol Ther · June 2026 INTRODUCTION: Control of chronic inflammatory diseases (CIDs) during pregnancy is essential for maternal and foetal health; however, the impact of pregnancy on the pharmacokinetics (PK) of CID therapies is unknown. This study investigated the impact of pre ... Full text Link to item Cite

Serum BAFF levels in pregnant patients with systemic lupus erythematosus.

Journal article Lupus · April 2026 Background/PurposeThe B cell Activating Factor (BAFF) signaling pathway influences rheumatic disease through its role in the selection, maturation, and survival of B cells. Increased BAFF also correlates with hypertension and preeclampsia in pregnant women ... Full text Link to item Cite

Reduced late endosome/lysosome function promotes SLE through chronic PI3K activity and SHP-1/SHIP-1 defects.

Journal article JCI Insight · March 23, 2026 Degradation of cellular waste from phagocytosis, endocytosis, and autophagy occurs through hydrolases that become activated during acidification of late endosomes and lysosomes (LELs). In our cross-sectional study, we showed diminished LEL acidification an ... Full text Link to item Cite

The Plot Thickens: From a Classic Presentation to Bilateral Renal Lesions.

Journal article Arthritis Care Res (Hoboken) · February 9, 2026 Full text Link to item Cite

Racial differences in medication beliefs and adherence barriers among patients with systemic lupus erythematosus.

Journal article Lupus · January 2026 IntroductionBlack patients with systemic lupus erythematosus (SLE) have lower medication adherence than White patients, contributing to worse health outcomes. However, racial differences in reasons for nonadherence and beliefs about medications are not wel ... Full text Open Access Link to item Cite

Improving Documentation Rates of Contraception and Reproductive Planning in Patients With Rheumatic Disease.

Journal article Arthritis Care Res (Hoboken) · October 2025 OBJECTIVE: This study aimed to improve contraception and reproductive planning documentation within rheumatology providers' notes at a single academic center. METHODS: Female patients aged 18 to 45 years with autoimmune inflammatory rheumatic diseases were ... Full text Link to item Cite

Moving the ACR's Reproductive Health Guidelines Into Practice: A Quantitative and Qualitative Assessment of a Novel Reproductive Rheumatology ECHO.

Journal article J Clin Rheumatol · August 1, 2025 BACKGROUND: Project ECHO (Extension for Community Healthcare Outcomes) links experts with community providers through video teleconferences that include both didactics and case discussions. We piloted the first ECHO with a specific focus on reproductive rh ... Full text Link to item Cite

Relationship between hydroxychloroquine blood levels and lupus activity through the lens of the type 1 and type 2 lupus model: a cross-sectional study.

Journal article Lupus Sci Med · June 30, 2025 INTRODUCTION: In the type 1 and 2 SLE model, inflammation mediates type 1 manifestations, but its role in type 2 manifestations (eg, fatigue, myalgias, mood disturbance, cognitive dysfunction) is less clear. Therapeutic hydroxychloroquine (HCQ) levels redu ... Full text Link to item Cite

Bringing Reproductive Health Guidelines Into Fellowship Training: A National Survey of Adult and Pediatric Rheumatology Fellows and Program Directors.

Journal article Arthritis Care Res (Hoboken) · March 2025 OBJECTIVE: This study seeks to assess rheumatology fellows' (RFs') and program directors' (PDs') interests in different educational tools and methods and to facilitate curriculum development for reproductive health related to rheumatic disease. METHODS: Co ... Full text Link to item Cite

Development and Pilot Testing of a Patient-Centered Reproductive Decision Aid for Pregnancy-Capable People With Rheumatic Diseases.

Journal article ACR Open Rheumatol · March 2025 OBJECTIVE: Although women with rheumatic and musculoskeletal diseases (RMDs) are at an elevated risk for adverse pregnancy and perinatal outcomes, some report that they lack access to resources that support informed reproductive decision-making. We develop ... Full text Link to item Cite

Second Trimester Kidney Function and Adverse Pregnancy Outcomes among Patients with Lupus.

Journal article Kidney360 · February 14, 2025 KEY POINTS: In our combined cohort, second trimester kidney function was associated with adverse outcomes for patients with lupus. Measurement of kidney function during pregnancy may have potential benefit, especially among patients without kidney disease. ... Full text Link to item Cite

Perspectives of Rheumatologists on the Type 1 and 2 Systemic Lupus Erythematosus Model.

Journal article ACR Open Rheumatol · December 2024 OBJECTIVE: The Type 1 and 2 systemic lupus erythematosus (SLE) Model was developed to encapsulate all signs and symptoms that patients with SLE experience. Our previous qualitative work demonstrated the model accurately reflects the lived experience of peo ... Full text Open Access Link to item Cite

Reproductive Outcomes for Women With Vasculitis.

Journal article J Rheumatol · October 1, 2024 OBJECTIVE: There are limited data on the reproductive health of women with vasculitis. This study used a prospective, international vasculitis pregnancy registry to survey women during and after pregnancy. METHODS: The Vasculitis Pregnancy Registry (VPREG) ... Full text Link to item Cite

Exploring Reproductive Experiences With Women Enrolled in the International Vasculitis Pregnancy Registry.

Journal article J Rheumatol · October 1, 2024 OBJECTIVE: This study explored the reproductive journeys of women with vasculitis, including their conversations with healthcare providers, disease activity, medication changes, and delivery experiences. METHODS: Interviews were conducted with women regist ... Full text Link to item Cite

Pregnancy Outcomes in Patients Treated with Upadacitinib: Analysis of Data from Clinical Trials and Postmarketing Reports.

Journal article Drug Saf · October 2024 BACKGROUND AND OBJECTIVE: Upadacitinib is indicated for diseases affecting persons of childbearing potential including rheumatoid arthritis, psoriatic arthritis, axial spondyloarthritis, atopic dermatitis, Crohn's disease, and ulcerative colitis; however, ... Full text Link to item Cite

Using linked electronic medical record-pharmacy data to examine lupus medication adherence: A retrospective cohort study.

Journal article Lupus · October 2024 INTRODUCTION: Medication nonadherence is common in systemic lupus erythematosus (SLE) and associated with morbidity and mortality. We explored the reliability of pharmacy data within the electronic medical record (EMR) to examine factors associated with no ... Full text Link to item Cite

The Impact of Pregnancy Readiness on Lupus Activity, Maternal Mental Health, and Pregnancy Outcomes.

Journal article Arthritis Care Res (Hoboken) · September 8, 2024 OBJECTIVE: Among individuals with systemic lupus erythematosus (SLE) who became pregnant, we explored the impact of medical readiness for pregnancy and personal readiness for pregnancy on the following aspects of maternal health: (1) provider-reported dise ... Full text Link to item Cite

Implementation of a Clinician-led Medication Adherence Intervention Among Patients With Systemic Lupus Erythematosus.

Journal article J Rheumatol · September 1, 2024 OBJECTIVE: Medication nonadherence in systemic lupus erythematosus (SLE) leads to poor clinical outcomes. We developed a clinician-led adherence intervention that involves reviewing real-time pharmacy refill data and using effective communication to addres ... Full text Open Access Link to item Cite

Alignment of contraception use with the ACR reproductive health guidelines in women with systemic lupus erythematosus within the RISE registry.

Journal article Lupus Sci Med · August 24, 2024 OBJECTIVES: Contraception is crucial for safely timing pregnancies in patients with SLE. This study investigated predictors of contraception documentation in patients with SLE, and the alignment of contraception practices with the 2020 American College of ... Full text Link to item Cite

Evaluating Factors Associated With Telehealth Appropriateness in Outpatient Rheumatoid Arthritis Encounters Using the Encounter Appropriateness Score for You (EASY).

Journal article J Rheumatol · August 1, 2024 OBJECTIVE: Telehealth has been proposed as a safe and effective alternative to in-person care for rheumatoid arthritis (RA). The purpose of this study was to evaluate factors associated with telehealth appropriateness in outpatient RA encounters. METHODS: ... Full text Open Access Link to item Cite

The time of equipoise on the use of biological DMARDs in for inflammatory arthritis during pregnancy is finally over: a reappraisal of evidence to optimise pregnancy management.

Journal article Lancet Rheumatol · August 2024 Active inflammatory arthritis in pregnancy is associated with an increased risk of adverse pregnancy outcomes. Treatment of active inflammation and maintenance of low disease activity with medication reduces these risks. Therapeutic decisions on disease-mo ... Full text Link to item Cite

Patient and Physician Perspectives of Systemic Lupus Erythematosus Flare: A Qualitative Study.

Journal article J Rheumatol · May 1, 2024 OBJECTIVE: Systemic lupus erythematosus (SLE) flares are associated with increased damage and decreased health-related quality of life. We hypothesized that there is discordance between physicians' and patients' views of SLE flare. In this study, we aimed ... Full text Link to item Cite

Contraception Care Patterns for Adult Females With Juvenile Idiopathic Arthritis on Teratogens in the Rheumatology Informatics System for Effectiveness (RISE) Registry.

Journal article J Rheumatol · May 1, 2024 Full text Link to item Cite

Interpreting hydroxychloroquine blood levels for medication non-adherence: a pharmacokinetic study.

Journal article Lupus Sci Med · April 30, 2024 OBJECTIVE: Characterise the relationship between hydroxychloroquine (HCQ) blood levels and the number of missed doses, accounting for dosage, dose timing and the large variability in pharmacokinetics (PK) between patients. METHODS: We externally validated ... Full text Link to item Cite

Evaluation of Type 2 SLE symptoms in patients with a range of lupus nephritis activity.

Journal article Clin Rheumatol · April 2024 BACKGROUND: Type 2 systemic lupus erythematosus (SLE) symptoms, including fatigue, fibromyalgia, and brain fog, contribute to poor health-related quality of life (HRQoL) in patients with lupus. To test the hypothesis that Type 1 (classical inflammatory lup ... Full text Link to item Cite

Impact of preeclampsia on infant and maternal health among women with rheumatic diseases.

Journal article Lupus · April 2024 OBJECTIVES: We sought to identify the impact of preeclampsia on infant and maternal health among women with rheumatic diseases. METHODS: A retrospective single-center cohort study was conducted to describe pregnancy and infant outcomes among women with sys ... Full text Link to item Cite

The impact of US abortion policy on rheumatology clinical practice: a cross-sectional survey of rheumatologists.

Journal article Arthritis Rheumatol · March 2024 Full text Link to item Cite

Evaluating Provider Perceptions of Telehealth Utility in Outpatient Rheumatology Telehealth Encounters.

Journal article J Clin Rheumatol · March 1, 2024 OBJECTIVE: This study aims to explore the factors associated with rheumatology providers' perceptions of telehealth utility in real-world telehealth encounters. METHODS: From September 14, 2020 to January 31, 2021, 6 providers at an academic medical center ... Full text Link to item Cite

The Type 1 & 2 systemic lupus erythematosus model: Perspectives of people living with systemic lupus erythematosus.

Journal article Lupus · March 2024 OBJECTIVE: In the new Type 1 & 2 model for systemic lupus erythematosus (SLE), Type 1 SLE represents classic inflammatory manifestations, such as arthritis, while Type 2 SLE encompasses symptoms such as pain and fatigue where the relationship to inflammati ... Full text Link to item Cite

Mycophenolate mofetil withdrawal in patients with systemic lupus erythematosus: a multicentre, open-label, randomised controlled trial.

Journal article Lancet Rheumatol · March 2024 BACKGROUND: Mycophenolate mofetil is an immunosuppressant commonly used to treat systemic lupus erythematosus (SLE) and lupus nephritis. It is a known teratogen associated with significant toxicities, including an increased risk of infections and malignanc ... Full text Link to item Cite

A qualitative study of facilitators of medication adherence in systemic lupus erythematosus: Perspectives from rheumatology providers/staff and patients.

Journal article Lupus · February 2024 OBJECTIVE: Systemic lupus erythematosus (SLE) disproportionately affects patients from racial and ethnic minority groups. Medication adherence is lower among these patient populations, and nonadherence is associated with worse health outcomes. We aimed to ... Full text Open Access Link to item Cite

Implications of the accuracy of diagnostic algorithms for systemic lupus on our understanding of racial disparities in pregnancy outcomes.

Journal article Rheumatology (Oxford) · January 4, 2024 OBJECTIVE: Disparities in pregnancy outcomes among women with SLE remain understudied, with few available racially diverse datasets. We sought to identify disparities between Black and White women in pregnancy outcomes within academic institutions in the U ... Full text Link to item Cite

Azathioprine metabolite levels and outcomes during pregnancies with rheumatic disease.

Journal article Lupus Sci Med · January 3, 2024 OBJECTIVE: Despite widespread use of azathioprine (AZA) during pregnancy, no studies evaluated the impact of pregnancy on AZA metabolites 6-thioguanine nucleotide (6-TGN) and 6-methylmercaptopurine nucleotide (6-MMPN) disposition in rheumatic diseases. Thi ... Full text Link to item Cite

Encounter Appropriateness Score for You Model: Development and Pilot Implementation of a Predictive Model to Identify Visits Appropriate for Telehealth in Rheumatology.

Journal article Arthritis Care Res (Hoboken) · January 2024 OBJECTIVE: We aimed to develop a decision-making tool to predict telehealth appropriateness for future rheumatology visits and expand telehealth care access. METHODS: The model was developed using the Encounter Appropriateness Score for You (EASY) and elec ... Full text Link to item Cite

Using PROMIS-29 to determine symptom burdens in the context of the Type 1 and 2 systemic lupus erythematosus (SLE) model: a cross sectional study.

Journal article J Patient Rep Outcomes · December 21, 2023 OBJECTIVE: To account for heterogeneity in systemic lupus erythematosus (SLE) and bridge discrepancies between patient- and physician-perceived SLE activity, we developed the Type 1 and 2 SLE model. We examined PROMIS-29 scores, a composite patient-reporte ... Full text Link to item Cite

Development and psychometric evaluation of a physician global assessment for type 2 systemic lupus erythematosus symptoms.

Journal article Lupus Sci Med · December 17, 2023 OBJECTIVE: Manifestations of SLE can be categorised as type 1 (classic signs and symptoms of SLE) or type 2 (fatigue, widespread pain and brain fog with an unclear relationship to inflammation). While measures of type 1 SLE activity exist, most current phy ... Full text Link to item Cite

The impact of pregnancy planning and medical readiness on reproductive outcomes in women with systemic lupus erythematosus.

Journal article Lupus · December 2023 Women with systemic lupus erythematosus (SLE) who get pregnant while SLE is active or while on teratogens have higher risk of poor pregnancy outcomes. The American College of Rheumatology (ACR) Reproductive Health Guidelines recommend women conceive when S ... Full text Link to item Cite

Hospital Admissions and Mortality in Patients With Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis.

Journal article J Clin Rheumatol · September 1, 2023 BACKGROUND/OBJECTIVES: Anti-neutrophil cytoplasmic antibody-associated vasculitis has reported hospital mortality rates ranging between 10% and 20% with inadequate information regarding causes and outcomes of these hospitalizations. Characterization of out ... Full text Link to item Cite

Using pooled electronic health records data to conduct pharmacoepidemiology safety studies: Challenges and lessons learned.

Journal article Pharmacoepidemiol Drug Saf · September 2023 PURPOSE: We assessed the suitability of pooled electronic health record (EHR) data from clinical research networks (CRNs) of the patient-centered outcomes research network to conduct studies of the association between tumor necrosis factor inhibitors (TNFi ... Full text Link to item Cite

Global comment on the use of hydroxychloroquine during the periconception period and pregnancy in women with autoimmune diseases.

Journal article Lancet Rheumatol · September 2023 Full text Link to item Cite

High frequency of teratogen prescriptions to women of reproductive age with rheumatic disease.

Journal article Arthritis Rheumatol · August 2023 Full text Link to item Cite

Vasculitis and Pregnancy: Disease State and Management.

Journal article Rheum Dis Clin North Am · August 2023 Family planning in women with vasculitis requires an interdisciplinary approach. This article summarizes recommendations and guidance for each phase of family planning in persons with vasculitis including preconception counseling, birth control, pregnancy, ... Full text Link to item Cite

The SPROUT study: A survey on current management practice of reproductive aspects in women of childbearing age with systemic autoimmune rheumatic diseases.

Journal article Autoimmun Rev · August 2023 The SPROUT (Survey on reproduction in RheUmaTology) study explored current practice in women of childbearing age with systemic autoimmune rheumatic diseases, investigating the counselling on contraception, the prescription of low dose acetylsalicylic acid ... Full text Link to item Cite

Obstetric outcomes in women with rheumatic disease and COVID-19 in the context of vaccination status.

Journal article Rheumatology (Oxford) · April 3, 2023 OBJECTIVE: To describe obstetric outcomes based on COVID-19 vaccination status, in women with rheumatic and musculoskeletal diseases (RMDs) who developed COVID-19 during pregnancy. METHODS: Data regarding pregnant women entered into the COVID-19 Global Rhe ... Full text Link to item Cite

Frequency of Contraception Documentation in Women With Systemic Lupus Erythematosus and Rheumatoid Arthritis Within the Rheumatology Informatics System for Effectiveness Registry.

Journal article Arthritis Care Res (Hoboken) · March 2023 OBJECTIVE: We sought to understand the frequency of contraception documentation for women with systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) in a large US electronic health record (EHR)-based registry and to identify disparities by terat ... Full text Link to item Cite

Pilot Intervention to Improve Medication Adherence Among Patients With Systemic Lupus Erythematosus Using Pharmacy Refill Data.

Journal article Arthritis Care Res (Hoboken) · March 2023 OBJECTIVE: Despite high rates of medication nonadherence among patients with systemic lupus erythematosus (SLE), effective interventions to improve adherence in SLE are limited. We aimed to assess the feasibility of a pilot intervention and explore its eff ... Full text Open Access Link to item Cite

Immunology of pregnancy and reproductive health in autoimmune rheumatic diseases. Update from the 11th International Conference on Reproduction, Pregnancy and Rheumatic Diseases.

Journal article Autoimmun Rev · March 2023 Autoimmune rheumatic diseases (ARD) can affect women and men during fertile age, therefore reproductive health is a priority issue in rheumatology. Many topics need to be considered during preconception counselling: fertility, the impact of disease-related ... Full text Link to item Cite

Belimumab use during pregnancy: a summary of birth defects and pregnancy loss from belimumab clinical trials, a pregnancy registry and postmarketing reports.

Journal article Ann Rheum Dis · February 2023 OBJECTIVE: Describe available data on birth defects and pregnancy loss in women with systemic lupus erythematosus (SLE) exposed to belimumab. METHODS: Data collected from belimumab clinical trials, the Belimumab Pregnancy Registry (BPR), and postmarketing/ ... Full text Link to item Cite

How to Provide Sexual and Reproductive Health Care to Patients: Focus Groups With Rheumatologists and Rheumatology Advanced Practice Providers.

Journal article J Rheumatol · February 2023 OBJECTIVE: Rheumatologists have identified challenges to providing sexual and reproductive health (SRH) care to patients with gestational capacity. We conducted focus groups with rheumatologists and rheumatology advanced practice providers (APPs) to elicit ... Full text Link to item Cite

Development and Initial Validation of a Systemic Lupus Erythematosus-Specific Measure of the Extent of and Reasons for Medication Nonadherence.

Journal article J Rheumatol · February 2023 Full text Open Access Link to item Cite

Molecular endotypes of type 1 and type 2 SLE.

Journal article Lupus Sci Med · January 2023 OBJECTIVE: To character the molecular landscape of patients with type 1 and type 2 SLE by analysing gene expression profiles from peripheral blood. METHODS: Full transcriptomic RNA sequencing was carried out on whole blood samples from 18 subjects with SLE ... Full text Link to item Cite

Overturning Roe v. Wade: Toppling the Practice of Rheumatology.

Journal article Arthritis Rheumatol · December 2022 Full text Link to item Cite

A comprehensive guide for managing the reproductive health of patients with vasculitis.

Journal article Nat Rev Rheumatol · December 2022 Vasculitides and their therapies affect all areas of the reproductive life cycle. The ACR, EULAR and the Drugs and Lactation database offer guidance on the management of the reproductive health of patients with rheumatic diseases; however, these guidelines ... Full text Link to item Cite

Development and Initial Validation of a Systemic Lupus Erythematosus-Specific Measure of the Extent of and Reasons for Medication Nonadherence.

Journal article J Rheumatol · December 2022 OBJECTIVE: Medication nonadherence is common in patients with systemic lupus erythematosus (SLE) and negatively affects outcomes. To better recognize and address nonadherence in this population, there is a need for an easily implementable tool with interpr ... Full text Link to item Cite

Pregnancy Outcomes in Undifferentiated Connective Tissue Disease Compared to Systemic Lupus Erythematosus: A Single Academic Center's Experience.

Journal article Arthritis Care Res (Hoboken) · October 2022 OBJECTIVE: Systemic lupus erythematosus (SLE) patients have more pregnancy complications than healthy patients. Data regarding pregnancy outcomes in women with undifferentiated connective tissue disease (UCTD) are more limited, and existing studies are con ... Full text Link to item Cite

Telehealth Made EASY: Understanding Provider Perceptions of Telehealth Appropriateness in Outpatient Rheumatology Encounters.

Journal article ACR Open Rheumatol · October 2022 OBJECTIVE: The purpose of this study was to evaluate a novel scoring system, the Encounter Appropriateness Score for You (EASY), to assess provider perceptions of telehealth appropriateness in rheumatology encounters. METHODS: The EASY scoring system promp ... Full text Open Access Link to item Cite

The association of lupus nephritis with adverse pregnancy outcomes among women with lupus in North America.

Journal article Lupus · October 2022 OBJECTIVES: We evaluated the association of lupus nephritis (LN) and adverse pregnancy outcomes in prospective cohorts of pregnant women with SLE (systemic lupus erythematosus). METHODS: We conducted a patient-level pooled analysis of data from three cohor ... Full text Link to item Cite

Barriers to Taking Medications for Systemic Lupus Erythematosus: A Qualitative Study of Racial Minority Patients, Lupus Providers, and Clinic Staff.

Journal article Arthritis Care Res (Hoboken) · September 2022 OBJECTIVE: Underrepresented racial and ethnic minorities are disproportionately affected by systemic lupus erythematosus (SLE). Racial and ethnic minorities also have more severe SLE manifestations that require use of immunosuppressive medications, and oft ... Full text Open Access Link to item Cite

Unintended Consequences of SCOTUS Abortion Decision for Patients With Rheumatic Diseases.

Journal article Ann Intern Med · September 2022 Full text Link to item Cite

Intermittent and Persistent Type 2 lupus: patient perspectives on two distinct patterns of Type 2 SLE symptoms.

Journal article Lupus Sci Med · August 2022 OBJECTIVE: We have developed a new conceptual model to characterise the signs and symptoms of SLE: the Type 1 and 2 SLE Model. Within the original model, Type 1 SLE consists of inflammatory manifestations like arthritis, nephritis and rashes; Type 2 SLE in ... Full text Link to item Cite

Association of Health Literacy and Numeracy With Lupus Knowledge and the Creation of the Lupus Knowledge Assessment Test.

Journal article J Rheumatol · June 2022 OBJECTIVE: Limited health literacy and numeracy are associated with worse patient-reported outcomes and higher disease activity in systemic lupus erythematosus (SLE), but which factors may mediate this association is unknown. We sought to determine the ass ... Full text Link to item Cite

Developing and Validating Methods to Assemble Systemic Lupus Erythematosus Births in the Electronic Health Record.

Journal article Arthritis Care Res (Hoboken) · May 2022 OBJECTIVE: Electronic health records (EHRs) represent powerful tools to study rare diseases. Our objective was to develop and validate EHR algorithms to identify systemic lupus erythematosus (SLE) births across centers. METHODS: We developed algorithms in ... Full text Link to item Cite

The use of patient-reported outcome measures to classify type 1 and 2 systemic lupus erythematosus activity.

Journal article Lupus · May 2022 OBJECTIVE: We developed a model that categorizes systemic lupus erythematosus (SLE) activity into two dimensions: Type 1 SLE consists of inflammatory activity, including arthritis, nephritis, and rashes; Type 2 SLE includes fatigue, myalgia, mood disturban ... Full text Link to item Cite

The Impact of the COVID-19 Pandemic and Telemedicine Implementation on Practice Patterns and Electronic Health Record Utilization in an Academic Rheumatology Practice.

Journal article J Clin Rheumatol · March 1, 2022 Full text Link to item Cite

Hydroxychloroquine in the pregnancies of women with lupus: a meta-analysis of individual participant data.

Journal article Lupus Sci Med · March 2022 OBJECTIVE: Multiple guidelines recommend continuing hydroxychloroquine (HCQ) for SLE during pregnancy based on observational data. The goal of this individual patient data meta-analysis was to identify the potential benefits and harms of HCQ use within lup ... Full text Link to item Cite

Hydroxychloroquine PK and exposure-response in pregnancies with lupus: the importance of adherence for neonatal outcomes.

Journal article Lupus Sci Med · January 2022 OBJECTIVE: Evaluate the impact of pregnancy physiology and medication non-adherence on serum hydroxychloroquine (HCQ) pharmacokinetics (PK) and exposure-response in SLE. METHODS: We conducted a PK analysis using data from two observational pregnancy regist ... Full text Link to item Cite

A glimpse into the future of systemic lupus erythematosus.

Journal article Ther Adv Musculoskelet Dis · 2022 This viewpoint article on a forecast of clinically meaningful changes in the management of systemic lupus erythematosus (SLE) in the next 10 years is based on a review of the current state of the art. The groundwork has been laid by a robust series of clas ... Full text Link to item Cite

Pharmacovigilance pregnancy data in a large population of patients with chronic inflammatory disease exposed to certolizumab pegol.

Journal article Ther Adv Musculoskelet Dis · 2022 INTRODUCTION: Chronic inflammatory diseases (CIDs), including rheumatic diseases and other inflammatory conditions, often affect women of reproductive age. Tumor necrosis factor inhibitors (TNFi) are widely used to treat CID, but there is limited informati ... Full text Link to item Cite

The importance of weight stabilization amongst those with overweight or obesity: Results from a large health care system.

Journal article Prev Med Rep · December 2021 Data on patterns of weight change among adults with overweight or obesity are minimal. We aimed to examine patterns of weight change and associated hospitalizations in a large health system, and to develop a model to predict 2-year significant weight gain. ... Full text Link to item Cite

Optimizing reproductive health management in lupus and Sjogren's syndrome.

Journal article Curr Opin Rheumatol · November 1, 2021 PURPOSE OF REVIEW: People with childbearing capacity who are diagnosed with systemic lupus erythematosus (SLE) and Sjogren's syndrome (SS) have specific and important reproductive health considerations. RECENT FINDINGS: Recommendations from the European Le ... Full text Link to item Cite

Exploring the Preferences of Women Regarding Sexual and Reproductive Health Care in the Context of Rheumatology: A Qualitative Study.

Journal article Arthritis Care Res (Hoboken) · August 2021 OBJECTIVE: To explore the sexual and reproductive health (SRH) care and counseling needs of young women with rheumatic diseases in the context of their rheumatology care. METHODS: Semistructured qualitative telephone interviews were conducted with female p ... Full text Link to item Cite

Racial Differences in Patient-provider Communication, Patient Self-efficacy, and Their Associations With Systemic Lupus Erythematosus-related Damage: A Cross-sectional Survey.

Journal article J Rheumatol · July 2021 OBJECTIVE: Despite significant racial disparities in systemic lupus erythematosus (SLE) outcomes, few studies have examined how disparities may be perpetuated in clinical encounters. We aimed to explore associations between areas of clinical encounters - p ... Full text Open Access Link to item Cite

Tough Choices: Exploring Medication Decision-Making During Pregnancy and Lactation Among Women With Inflammatory Arthritis.

Journal article ACR Open Rheumatol · July 2021 OBJECTIVE: This study explored how women's beliefs about drug safety and interactions with their health care providers influenced their decisions to continue arthritis medications during pregnancy and lactation. METHODS: We collaborated with ArthritisPower ... Full text Link to item Cite

The Categorization of Pain in Systemic Lupus Erythematosus.

Journal article Rheum Dis Clin North Am · May 2021 Systemic lupus erythematous is a systemic autoimmune disease that can cause severe pain and impair quality of life. Pain in lupus can arise from a variety of mechanisms and is usually assessed in terms of activity and damage. In contrast, categorization of ... Full text Link to item Cite

The importance of pregnancy planning in lupus pregnancies.

Journal article Lupus · April 2021 OBJECTIVE: In seeking new approaches to improve lupus pregnancy outcomes, we study the association between pregnancy planning, behaviors recommended by American College of Rheumatology's Reproductive Health Guideline 2020, and pregnancy and infant outcomes ... Full text Link to item Cite

Breastfeeding in women with rheumatic diseases.

Journal article Lupus Sci Med · April 2021 OBJECTIVE: Many rheumatologists and women with rheumatic disease worry that the disease or treatment will prevent breast feeding. International guidelines establish, however, that most antirheumatic medications are compatible with breast feeding. We sought ... Full text Link to item Cite

Using Clinical Characteristics and Patient-Reported Outcome Measures to Categorize Systemic Lupus Erythematosus Subtypes.

Journal article Arthritis Care Res (Hoboken) · March 2021 OBJECTIVE: The type 1 and type 2 systemic lupus erythematosus (SLE) categorization system was recently proposed to validate the patients' perspective of disease and to capture a more comprehensive spectrum of symptoms. The objective of this study was to ch ... Full text Link to item Cite

Low health numeracy is associated with higher disease activity in systemic lupus erythematosus.

Journal article Lupus · March 2021 OBJECTIVE: Evidence suggests low health literacy is prevalent in the United States and associated with worse clinical outcomes, yet few studies have investigated health literacy in systemic lupus erythematosus (SLE). The objective of this study was to dete ... Full text Link to item Cite

Impact of the COVID-19 pandemic on patterns of outpatient cardiovascular care.

Journal article Am Heart J · January 2021 BACKGROUND: The coronavirus disease 2019 (COVID-19) pandemic brought about abrupt changes in the way health care is delivered, and the impact of transitioning outpatient clinic visits to telehealth visits on processes of care and outcomes is unclear. METHO ... Full text Link to item Cite

Investigating Health Literacy in Systemic Lupus Erythematosus: a Descriptive Review.

Journal article Curr Allergy Asthma Rep · November 12, 2020 PURPOSE OF REVIEW: Inadequate health literacy is common among American adults, but little is known about the impact of health literacy in rheumatic diseases. The purpose of this article is to review studies investigating health literacy and its association ... Full text Link to item Cite

Learning to listen: how empathetic engagement with patients can help overcome reproductive injustice.

Journal article Lupus Sci Med · November 2020 Full text Link to item Cite

Dr. Balevic, et al reply.

Journal article J Rheumatol · October 1, 2020 Full text Link to item Cite

Reproductive health needs of adolescent and young adult women with pediatric rheumatic diseases.

Journal article Pediatr Rheumatol Online J · August 17, 2020 BACKGROUND: The purpose of this study was to identify reproductive health knowledge gaps and topics that concern adolescent and young adult (AYA) women with pediatric rheumatic diseases and their parents. METHODS: Data collection occurred in two cohorts. I ... Full text Link to item Cite

Racial Disparities in Medication Adherence between African American and Caucasian Patients With Systemic Lupus Erythematosus and Their Associated Factors.

Journal article ACR Open Rheumatol · July 2020 OBJECTIVE: Medication nonadherence is more common in African Americans compared with Caucasians. We examined the racial adherence gaps among patients with systemic lupus erythematosus (SLE) and explored factors associated with nonadherence. METHODS: Cross- ... Full text Open Access Link to item Cite

Pregnancy outcomes, fertility, and family planning in women with psoriatic arthritis.

Journal article Obstet Med · June 2020 OBJECTIVE: To quantify pregnancy outcomes and the frequency and cause of infertility among women with psoriatic arthritis. METHODS: Women with psoriatic arthritis aged 20-50 years completed a questionnaire about prior pregnancies, infertility, and family p ... Full text Link to item Cite

Impact of a Multifaceted Educational Program to Improve Provider Skills for Lupus Pregnancy Planning and Management: A Mixed-Methods Approach.

Journal article ACR Open Rheumatol · June 2020 OBJECTIVE: To bring recent advances in pregnancy management in lupus to women nationwide, this multidimensional educational intervention sought to equip community rheumatologists with the needed skills, attitudes, and confidence to manage contraceptive dec ... Full text Open Access Link to item Cite

Hydroxychloroquine in Patients with Rheumatic Disease Complicated by COVID-19: Clarifying Target Exposures and the Need for Clinical Trials.

Journal article J Rheumatol · May 11, 2020 OBJECTIVE: To characterize hydroxychloroquine (HCQ) exposure in patients with rheumatic disease receiving longterm HCQ compared to target concentrations with reported antiviral activity against the coronavirus disease 2019 caused by SARS-CoV-2 (COVID-19). ... Full text Link to item Cite

Antirheumatic medications in pregnancy and breastfeeding.

Journal article Curr Opin Rheumatol · May 2020 PURPOSE OF REVIEW: As active rheumatic and musculoskeletal disease during pregnancy increases the risk for pregnancy loss, preterm birth, and maternal illness, ongoing management with pregnancy-compatible medications can improve these outcomes. Selecting a ... Full text Link to item Cite

2020 American College of Rheumatology Guideline for the Management of Reproductive Health in Rheumatic and Musculoskeletal Diseases.

Journal article Arthritis Care Res (Hoboken) · April 2020 OBJECTIVE: To develop an evidence-based guideline on contraception, assisted reproductive technologies (ART), fertility preservation with gonadotoxic therapy, use of menopausal hormone replacement therapy (HRT), pregnancy assessment and management, and med ... Full text Link to item Cite

2020 American College of Rheumatology Guideline for the Management of Reproductive Health in Rheumatic and Musculoskeletal Diseases.

Journal article Arthritis Rheumatol · April 2020 OBJECTIVE: To develop an evidence-based guideline on contraception, assisted reproductive technologies (ART), fertility preservation with gonadotoxic therapy, use of menopausal hormone replacement therapy (HRT), pregnancy assessment and management, and med ... Full text Link to item Cite

Perspectives of Adult Rheumatologists Regarding Family Planning Counseling and Care: A Qualitative Study.

Journal article Arthritis Care Res (Hoboken) · March 2020 OBJECTIVE: Little is known about whether and how rheumatologists provide family planning counseling and reproductive health care (FPCC) to reproductive-age women with rheumatic diseases. This qualitative study sought to assess rheumatologists' perspectives ... Full text Link to item Cite

Effect of aspirin response signature gene expression on preterm birth and preeclampsia among women with lupus: a pilot study.

Journal article Lupus · December 2019 BACKGROUND: Women with lupus have an increased risk of preeclampsia and preterm birth, and aspirin 81 mg/day is recommended as a preventative measure for preeclampsia. This pilot study quantified the association between a 60-gene aspirin response signature ... Full text Link to item Cite

Pregnancy in Women With Lupus: We Have Come So Far and Have So Far to Go.

Journal article Ann Intern Med · August 6, 2019 Full text Link to item Cite

Contraception Use Among Reproductive-Age Women With Rheumatic Diseases.

Journal article Arthritis Care Res (Hoboken) · August 2019 OBJECTIVE: To determine contraception use among a cohort of reproductive-age women (ages 18-50 years) with rheumatic diseases. METHODS: We conducted a study of administrative data from a single, large medical center between the years 2013 and 2014. Women w ... Full text Link to item Cite

A Novel System to Categorize the Symptoms of Systemic Lupus Erythematosus.

Journal article Arthritis Care Res (Hoboken) · June 2019 Full text Link to item Cite

Response to: 'Postpartum breastfeeding status' by Betzold.

Journal article Ann Rheum Dis · May 2019 Full text Link to item Cite

Fertility and Ovarian Reserve among Women with Rheumatoid Arthritis.

Journal article J Rheumatol · May 2019 OBJECTIVE: We sought to identify causes for infertility in women with and without rheumatoid arthritis (RA). METHODS: Women with RA were matched to healthy controls. Differences in anti-Müllerian hormone (AMH) and anovulation were analyzed. RESULTS: Women ... Full text Link to item Cite

Pharmacokinetics of Hydroxychloroquine in Pregnancies with Rheumatic Diseases.

Journal article Clin Pharmacokinet · April 2019 BACKGROUND: Hydroxychloroquine is an oral drug prescribed to pregnant women with rheumatic disease to reduce disease activity and prevent flares. Physiologic changes during pregnancy may substantially alter drug pharmacokinetics. However, the effect of pre ... Full text Link to item Cite

Contraception methods used by women with rheumatoid arthritis and psoriatic arthritis.

Journal article Clin Rheumatol · April 2019 Rheumatoid arthritis (RA) and psoriatic arthritis (PsA) are common in women of childbearing age and are often treated with teratogenic medications. In this study, we assessed contraceptive methods in young women with RA or PsA and correlated contraceptive ... Full text Link to item Cite

Pregnancy, Periods, and "The Pill": Exploring the Reproductive Experiences of Women with Inflammatory Arthritis.

Journal article ACR Open Rheumatol · April 2019 OBJECTIVE: Women with inflammatory arthritis appear to have fewer children as compared with healthy women, but few studies have assessed how patients' attitudes and decision making influence their family sizes. Little is also known about how patients exper ... Full text Link to item Cite

It Is Time to Modify Treatment to Enable More Women with Rheumatoid Arthritis to Have Successful Pregnancies.

Journal article J Rheumatol · March 2019 Full text Link to item Cite

Preconceptional Cardiovascular Health and Pregnancy Outcomes in Women with Systemic Lupus Erythematosus.

Journal article J Rheumatol · January 2019 OBJECTIVE: To estimate the effects of preconceptional cardiovascular (CV) health, measured by American Heart Association (AHA) guidelines, on pregnancy outcomes in women with systemic lupus erythematosus (SLE). METHODS: The study included patients in the H ... Full text Link to item Cite

Hydroxychloroquine Levels throughout Pregnancies Complicated by Rheumatic Disease: Implications for Maternal and Neonatal Outcomes.

Journal article J Rheumatol · January 2019 OBJECTIVE: Pregnancies in women with active rheumatic disease often result in poor neonatal outcomes. Hydroxychloroquine (HCQ) reduces disease activity and flares; however, pregnancy causes significant physiologic changes that may alter HCQ levels and lead ... Full text Link to item Cite

Provider perceptions on the management of lupus during pregnancy: barriers to improved care.

Journal article Lupus · January 2019 BACKGROUND: More than half of pregnancies in women with systemic lupus erythematosus (lupus) result in adverse outcomes for the mother or the fetus. We sought to identify aspects of current rheumatologic care that could be improved to decrease the frequenc ... Full text Link to item Cite

Development of ReproKnow, a reproductive knowledge assessment for women with rheumatic diseases.

Journal article BMC Rheumatol · 2019 BACKGROUND: The objective of this study was to develop an assessment tool, ReproKnow, to evaluate the reproductive health knowledge of women with a wide range of rheumatic diseases. METHODS: The 10-item multiple-choice questionnaire was developed with feed ... Full text Link to item Cite

Rheumatologists' knowledge of contraception, teratogens, and pregnancy risks.

Journal article Obstet Med · December 2018 INTRODUCTION: Rheumatologists are essential partners in planning and managing pregnancies in women with lupus. Whether they know the essentials of contraceptive and medical treatment in pregnancy, however, is unknown. METHOD: Anonymous in-lecture surveys w ... Full text Link to item Cite

Outcomes of Pregnancies With Maternal/Paternal Exposure in the Tofacitinib Safety Databases for Ulcerative Colitis.

Journal article Inflamm Bowel Dis · November 29, 2018 BACKGROUND: Active inflammatory bowel disease increases the risk of adverse pregnancy outcomes. Tofacitinib is an oral, small molecule Janus kinase inhibitor for the treatment of ulcerative colitis (UC). As a small molecule, tofacitinib is likely to cross ... Full text Link to item Cite

Pregnancy Outcomes After Exposure to Certolizumab Pegol: Updated Results From a Pharmacovigilance Safety Database.

Journal article Arthritis Rheumatol · September 2018 OBJECTIVE: Anti-tumor necrosis factor (anti-TNF) medications are effective in controlling chronic inflammatory diseases, but information about their use and safety in pregnancy is limited. Consequently, anti-TNF agents are often discontinued early in gesta ... Full text Link to item Cite

Power in numbers.

Journal article Rheumatology (Oxford) · July 1, 2018 Collecting useful data on a sufficiently large cohort of pregnancies in women with rheumatic disease is a challenge. The original manuscripts that demonstrated the dangers of pregnancy in women with lupus were relatively small case series. As larger prospe ... Full text Link to item Cite

The new FDA labeling rule: impact on prescribing rheumatological medications during pregnancy.

Journal article Rheumatology (Oxford) · July 1, 2018 After several decades of deliberation, the US Food and Drug Administration updated the Pregnancy and Lactation Labeling Rule in 2015, eliminating the prior A, B, C, D, X grading system for medication use in pregnancy. Although physicians and patients liked ... Full text Link to item Cite

Introduction

Journal article Rheumatology United Kingdom · July 1, 2018 Full text Cite

Use of Administrative Databases to Assess Reproductive Health Issues in Rheumatic Diseases.

Journal article Rheum Dis Clin North Am · May 2018 Administrative databases, registers, and other sources of big data can be interesting sources to address important research questions on reproduction in women with rheumatic diseases. There are many different types of administrative datasets worldwide, and ... Full text Link to item Cite

The impact of menopause on functional status in women with rheumatoid arthritis.

Journal article Rheumatology (Oxford) · May 1, 2018 OBJECTIVE: The aim of this study was to investigate the association of menopause with functional status outcomes in women with RA. METHODS: Participants were women in a US-wide observational cohort who developed RA before menopause. The HAQ measured functi ... Full text Link to item Cite

Patterns of prednisone use during pregnancy in women with rheumatoid arthritis: Daily and cumulative dose.

Journal article Pharmacoepidemiol Drug Saf · April 2018 PURPOSE: To characterize prednisone use in pregnant women with rheumatoid arthritis using individual-level heat-maps and clustering individual trajectories of prednisone dose, and to evaluate the association between prednisone dose trajectory groups and ge ... Full text Link to item Cite

Examination of Hydroxychloroquine Use and Hemolytic Anemia in G6PDH-Deficient Patients.

Journal article Arthritis Care Res (Hoboken) · March 2018 OBJECTIVE: Some sources urge caution when prescribing hydroxychloroquine (HCQ) to patients with G6PDH deficiency, presumably due to a risk of hemolytic anemia. There are limited published data, however, to support this risk. Additionally, not all patients ... Full text Link to item Cite

Reasons for cesarean and medically indicated deliveries in pregnancies in women with systemic lupus erythematosus.

Journal article Lupus · March 2018 Objective To determine reasons for cesarean and medically indicated deliveries in a registry of pregnant women with SLE compared to RA. Methods Pregnant women with SLE or RA were prospectively followed, and pregnancy outcomes were collected, including whet ... Full text Link to item Cite

Pregnancy in rheumatoid arthritis: a retrospective study.

Journal article Clin Rheumatol · March 2018 Full text Link to item Cite

Family Planning Counseling for Women With Rheumatic Diseases.

Journal article Arthritis Care Res (Hoboken) · February 2018 Full text Link to item Cite

Increasing contraception use among women receiving teratogenic medications in a rheumatology clinic.

Journal article BMJ Open Qual · 2018 Teratogenic medications are often prescribed to women of childbearing age with autoimmune diseases. Literature suggests that appropriate use of contraception among these women is low, potentially resulting in high-risk unintended pregnancies. Preliminary r ... Full text Open Access Link to item Cite

Minimal to no transfer of certolizumab pegol into breast milk: results from CRADLE, a prospective, postmarketing, multicentre, pharmacokinetic study.

Journal article Ann Rheum Dis · November 2017 BACKGROUND: Women with chronic inflammatory diseases face uncertainty regarding the safety of biologics during breast feeding. CRADLE was the first industry-sponsored study to evaluate certolizumab pegol (CZP) concentrations in human breast milk and estima ... Full text Link to item Cite

Gestational weight gain in women with systemic lupus erythematosus.

Journal article Lupus · May 2017 Objective The objective of this study was to estimate the proportion of pregnant women with systemic lupus erythematosus meeting Institute of Medicine guidelines for gestational weight gain and determine correlates of adherence to guidelines. Methods Singl ... Full text Link to item Cite

Vasculitis and Pregnancy.

Journal article Rheum Dis Clin North Am · May 2017 Vasculitis is more often a disease of women beyond their reproductive years, leaving the challenges of pregnancy management difficult to study. Pregnancy complications, including pregnancy loss and preterm birth, are higher among women with all forms of va ... Full text Link to item Cite

Efficacy and Safety of Epratuzumab in Moderately to Severely Active Systemic Lupus Erythematosus: Results From Two Phase III Randomized, Double-Blind, Placebo-Controlled Trials.

Journal article Arthritis Rheumatol · February 2017 OBJECTIVE: Epratuzumab, a monoclonal antibody that targets CD22, modulates B cell signaling without substantial reductions in the number of B cells. The aim of this study was to report the results of 2 phase III multicenter randomized, double-blind, placeb ... Full text Link to item Cite

Rheumatology Informatics System for Effectiveness: A National Informatics-Enabled Registry for Quality Improvement.

Journal article Arthritis Care Res (Hoboken) · December 2016 OBJECTIVE: The Rheumatology Informatics System for Effectiveness (RISE) is a national electronic health record (EHR)-enabled registry. RISE passively collects data from EHRs of participating practices, provides advanced quality measurement and data analyti ... Full text Link to item Cite

Evaluating transfer of certolizumab pegol into breast milk: Results from a prospective, postmarketing, multicenter pharmacokinetic study

Journal article Revue Du Rhumatisme Edition Francaise · November 1, 2016 Full text Cite

Racial and Ethnic Disparities in the Pregnancies of Women With Systemic Lupus Erythematosus.

Journal article Arthritis Care Res (Hoboken) · October 2016 OBJECTIVE: Both systemic lupus erythematosus (SLE; lupus) and pregnancy individually have significant racial disparities, with black women experiencing higher rates of complications, yet no large studies have focused on the impact of race/ethnicity on preg ... Full text Link to item Cite

Reporting of Sex Effects by Systematic Reviews on Interventions for Depression, Diabetes, and Chronic Pain.

Journal article Ann Intern Med · August 2, 2016 Systematic reviews (SRs) have the potential to contribute uniquely to the evaluation of sex and gender differences (termed "sex effects"). This article describes the reporting of sex effects by SRs on interventions for depression, type 2 diabetes mellitus, ... Full text Link to item Cite

Breastfeeding in mothers with systemic lupus erythematosus.

Journal article Lupus · August 2016 INTRODUCTION: Breastfeeding is known to improve the well-being of a mother and her infant, and about half of all new mothers breastfeed, but it is unknown how breastfeeding is pursued in systemic lupus erythematosus (SLE; lupus) patients. We sought to dete ... Full text Link to item Cite

Pregnancy Outcomes in the Tofacitinib Safety Databases for Rheumatoid Arthritis and Psoriasis.

Journal article Drug Saf · August 2016 INTRODUCTION: Tofacitinib is an oral Janus kinase inhibitor for the treatment of rheumatoid arthritis (RA), and is being investigated for the treatment of psoriasis. Both conditions can present in women of child-bearing potential, but pregnancy was an excl ... Full text Link to item Cite

Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Properties of SBI-087, a CD20-Directed B-cell Depleting Agent: Phase 1 Dose Escalating Studies in Patients With Either Mild Rheumatoid Arthritis or Systemic Lupus.

Journal article Clin Ther · June 2016 PURPOSE: SBI-087 is a Small Modular Immunopharmaceutical Protein™(SMIP™) drug that binds to CD20 and has been reported to deplete B cells in murine/primate studies. The safety, tolerability and pharmacokinetic/pharmacodynamic properties of SBI-087 were eva ... Full text Link to item Cite

Long-Term Safety and Efficacy of Epratuzumab in the Treatment of Moderate-to- Severe Systemic Lupus Erythematosus: Results From an Open-Label Extension Study.

Journal article Arthritis Care Res (Hoboken) · April 2016 OBJECTIVE: The primary objective was to assess the long-term safety of repeated courses of epratuzumab therapy in patients with moderate-to-severe systemic lupus erythematosus. Secondary objectives were to assess long-term efficacy and health-related quali ... Full text Link to item Cite

Pregnancy Outcomes in Subjects Exposed to Certolizumab Pegol.

Journal article J Rheumatol · December 2015 OBJECTIVE: To provide information on pregnancy outcomes in women receiving certolizumab pegol (CZP). METHODS: The UCB Pharma safety database was searched for pregnancies through to September 1, 2014. Reports for maternal and paternal CZP exposure were incl ... Full text Link to item Cite

A Fellow Led Quality Improvement Project for Improving Contraceptive Compliance in Women Receiving Teratogenic Medications

Journal article ARTHRITIS & RHEUMATOLOGY · October 1, 2015 Link to item Cite

State of the art: Reproduction and pregnancy in rheumatic diseases.

Journal article Autoimmun Rev · May 2015 Throughout the last decade, increasing awareness has been raised on issues related to reproduction in rheumatic diseases including basic research to clarify the important role of estrogens in the etiology and pathophysiology of immune/inflammatory diseases ... Full text Link to item Cite

Breastfeeding Practice in Patients with Systemic Lupus Erythematosus

Journal article CLINICAL AND EXPERIMENTAL RHEUMATOLOGY · May 1, 2015 Link to item Cite

Proceedings from the American College of Rheumatology Reproductive Health Summit: the management of fertility, pregnancy, and lactation in women with autoimmune and systemic inflammatory diseases.

Journal article Arthritis Care Res (Hoboken) · March 2015 Full text Link to item Cite