Journal articleJournal Of Biomechanics · July 2009
Integrative biomechanics uses biomechanics knowledge and methods at multiple scales and among biological entities to address fundamental and clinical problems at the tissue and organ level. Owing to the large ranges of scale involved, integrative biomechan ...
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Journal articleInternational journal of cardiology · June 2009
BackgroundThe non-uniform distribution of atherosclerosis in the human vasculature suggests that local fluid dynamics or wall mechanics may be involved in atherogenesis. Thus certain aspects of vascular geometry, which mediates both fluid dynamics ...
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Journal articleUltrasound In Medicine And Biology · November 2008
Intravascular ultrasound (IVUS) elastography is an imaging technique that obtains the local mechanical properties of the artery wall and atherosclerotic plaques through strain measurements using IVUS. Knowledge of these mechanical properties may provide cr ...
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Journal articleJournal of biomechanics · October 2008
Atherosclerotic plaque rupture is the major cause of acute coronary syndromes. Currently, there is no reliable diagnostic tool to predict plaque rupture. Knowledge of plaque mechanical properties based on local artery wall strain measurements would be usef ...
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Journal articleAmerican Journal Of Physiology-heart And Circulatory Physiology · October 2008
Endothelial cells (ECs) from different vascular beds display a remarkable heterogeneity in both structure and function. Phenotypic heterogeneity among arterial ECs is particularly relevant to atherosclerosis since the disease occurs predominantly in major ...
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Journal articleAmerican Journal Of Physiology-heart And Circulatory Physiology · November 2007
Individual and combined effects of shear stress magnitude and spatial gradient on endothelial cell gene expression. Am J Physiol Heart Circ Physiol 293: H2853-H2859, 2007. First published August 31, 2007; doi:10.1152/ajpheart.00244.2007. The apparent tende ...
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Journal articleAmerican journal of physiology. Heart and circulatory physiology · July 2007
As a result of the complex blood flow patterns that occur in the arterial tree, certain regions of the vessel wall experience fluctuations in shear stress that are dominated by harmonic frequencies higher than the heart rate (11). To assess whether variati ...
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Journal articleJournal of biomechanical engineering · December 2006
BackgroundIn vivo experimentation is the most realistic approach for exploring the vascular biological response to the hemodynamic stresses that are present in life. Post-mortem vascular casting has been used to define the in vivo geometry for hem ...
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Journal articleJournal of biomechanical engineering · December 2006
BackgroundTemporal variations in shear stress have been suggested to affect endothelial cell biology. To better quantify the range of dynamic shear forces that occur in vivo, the frequency content of shear variations that occur naturally over a ca ...
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Journal articleAtherosclerosis · February 2006
Hypercholesterolemia is associated with increased cardiovascular mortality and is known to promote the advancement of atherosclerotic lesions in experimental animal models. Juvenile swine were fed a normal or high-cholesterol diet, and the transendothelial ...
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Journal articleAnn. Biomed. Eng. (USA) · 2005
Large spatial shear stress gradients have anecdotally been associated with early atherosclerotic lesion susceptibility in vivo and have been proposed as promoters of endothelial cell dysfunction in vitro. Here, experiments are presented in which several me ...
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Journal articleAnn. Biomed. Eng. (USA) · 2005
Although primarily motivated by an interest in atherosclerosis, modeling of arterial blood flow is also important to an understanding of congenital effects and to improvements in therapeutics. A variety of methods are available to estimate the flow field i ...
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Journal articleJ. Biomech. (UK) · 2004
The coronary arteries undergo large dynamic variations during each cardiac cycle due to their position on the beating heart. The local artery curvature varies significantly. In this study the influence of dynamic curvature on coronary artery hemodynamics i ...
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Journal articleProc. SPIE - Int. Soc. Opt. Eng. (USA) · 2004
Atherosclerotic lesions have been shown to have different mechanical properties than the non-diseased artery. Calculating vessel wall strain from cross-sectional vessel wall motions allows for the measurement of local stiffness. In this paper, a robust met ...
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Journal articleJournal of biomechanics · May 2003
Stents have dramatically improved the treatment of coronary artery disease. Since the implantation of stents changes the geometry and dynamics of the coronary artery, it is reasonable to hypothesize that some of these changes may have an important effect o ...
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Journal articleProc. SPIE - Int. Soc. Opt. Eng. (USA) · 2003
Most of the quantitative measures from intravascular ultrasound (IVUS) images vary with the cardiac cycle. Although ECG-gated acquisition can prevent the pulsations from influencing the measurements, it may extend the acquisition time, and furthermore, ver ...
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Journal articleAnn. Biomed. Eng. (USA) · 2003
The purpose of this work was to investigate the effects of physiologically realistic cardiac-induced motion on hemodynamics in human right coronary arteries. The blood flow patterns were numerically simulated in a modeled right coronary artery (RCA) having ...
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Journal articleAnn. Biomed. Eng. (USA) · 2003
The hypothesis that much of the uptake of macromolecules by the vascular wall takes place while the endothelial lining is adapting to changes in its hemodynamic environment is being tested by a series of in vivo measurements of the uptake of Evans-blue-dye ...
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Journal articleAmerican Society of Mechanical Engineers, Bioengineering Division (Publication) BED · 2003
Evans blue dye (EBD) was injected into the carotid arteries of three anesthetized pigs and allowed to circulate for 90 minutes. At the conclusion of the 90-minute period, the animals were sacrificed and injection casts of the infrarenal aorta and iliac-fem ...
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Journal articleAnn. Biomed. Eng. (USA) · 2002
There is considerable evidence that the localization and evolution of vascular disease are mediated, at least in part, by mechanical factors. The mechanical environment of the coronary arteries, which are tethered to the beating heart, is influenced by car ...
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Journal articleProc. SPIE - Int. Soc. Opt. Eng. (USA) · 2002
The Windows version of the Night Vision Thermal Imaging System Performance Model, NVTherm, was released in March 2001. NVTherm provides accurate predictions of sensor performance for both well-sampled and undersampled thermal imagers. Since its initial fie ...
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Journal articleBiorheology (Netherlands) · 2002
Geometric parameters and features vary within the vasculature. Furthermore, at any given anatomic site, there are substantial variations in geometry among individuals. These variations can contribute to a corresponding variability in the hemodynamic enviro ...
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Journal articleProc. SPIE - Int. Soc. Opt. Eng. (USA) · 2002
We present a new method to segment the walls of coronary arteries in IVUS (intravascular ultrasound) images based on a deformable model, which integrates both edge and region information. The whole image is supposed to have three regions-lumen, vessel wall ...
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Journal articleTrans. ASME, J. Biomech. Eng. (USA) · 2001
The increasing importance of life science in all engineering is prompting departments in the traditional engineering disciplines to offer life science as part of their curricula. Students who take advantage of this opportunity-“biotraditional enginee ...
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Journal articleAmerican Society of Mechanical Engineers, Bioengineering Division (Publication) BED · 2001
The curvature effects on bifurcating coronary artery flow were discussed. A mathematical model was developed that employed the modified Navier-Stokes equations to describe the flow in a time-dependent geometry with large externally imposed boundary motion. ...
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Journal articleProc. SPIE - Int. Soc. Opt. Eng. (USA) · 2001
The motion of coronary arteries has attracted more and more attention because of its possible effects on the development of atherosclerosis and potential clinical application for diagnosis of cardiovascular disease. Angiography is the best clinical modalit ...
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Journal articleAnn. Biomed. Eng. (USA) · 2000
The effects of the outflow of aortic blood through the celiac and renal arteries on the flow field in the external iliac arteries were studied under steady and physiologically realistic pulsatile flow conditions. Laser Doppler velocimetry (LDV) measurement ...
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Journal articleAnn. Biomed. Eng. (USA) · 2000
A common approach to understanding the role of hemodynamics in atherogenesis is to seek relationships between parameters of the hemodynamic environment, and the distribution of tissue variables thought to be indicative of early disease. An important questi ...
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Journal articleBiorheology (Netherlands) · 2000
Experiments were carried out in swine to test the hypothesis that changes in the fluid dynamic environment of the arterial wall, with time constants of several minutes to perhaps a few hours, prompt adaptive responses that transiently increase endothelial ...
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Journal articleInt. J. Card. Imaging (Netherlands) · 2000
Speculation that the motion of the coronary arteries might be involved in the pathogenesis of coronary atherosclerosis has generated growing interest in the study of this motion. Accordingly, a system has been developed to quantify 3-D coronary arterial mo ...
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Journal articleTrans. ASME, J. Biomech. Eng. (USA) · 2000
Mechanical forces have been widely recognized to play an important role in the pathogenesis of atherosclerosis. Since coronary arterial motion modulates both vessel wall mechanics and fluid dynamics, it is hypothesized that certain motion patterns might be ...
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Journal articleAnnals of Biomedical Engineering · 2000
In this study, near-wall velocity measurements were obtained to estimate wall shear stress in human left coronary arteries due to their small diameter and the limitations of conventional measurement techniques. A 3-dimensional particle Tracking Velocimetry ...
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Journal articleAmerican Society of Mechanical Engineers, Bioengineering Division (Publication) BED · 1999
The present study describes a detailed methodology, from 3D image reconstruction to flow analysis, for simulating the flow field in real arterial geometries. The procedure takes advantage of the latest state of the art technology in solid modeling, and is ...
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Journal articleAmerican Society of Mechanical Engineers, Bioengineering Division (Publication) BED · 1999
Experiments are being carried out in swine to test the hypothesis that changes in the fluid dynamic environment of the arterial wall, with time constants of several minutes to perhaps a few hours, prompt adaptive responses that transiently increase endothe ...
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Journal articleBiorheology (Netherlands) · 1999
In support of an in vivo investigation in swine of the influence of changes in fluid dynamic wall shear on arterial macromolecular permeability, a procedure has been developed to alter the flows in the porcine posterior arterial vasculature by opening and ...
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Journal articleAmerican Society of Mechanical Engineers, Bioengineering Division (Publication) BED · 1999
Using a system developed to track and quantify the in vivo motion of coronary arteries from clinical biplane coronary cineangiograms, the in vivo dynamics of twelve coronary arteries were characterized. The results suggest that certain dynamic parameters o ...
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Journal articleJ. Biomech. (UK) · 1998
A system was developed to track the centerlines (axes) of human coronary arteries during the cardiac cycle from biplane cineangiograms. The system employs a time interpolation technique on one image plane and a smoothing technique on the other to create si ...
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Journal articleAmerican Society of Mechanical Engineers, Bioengineering Division (Publication) BED · 1998
In support of an in vivo investigation in swine of the influence of changes in fluid dynamic wall shear on arterial macromolecular permeability, a procedure has been developed to alter the flows in the porcine posterior arterial vasculature by opening and ...
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Journal articleJ. Biomech. (UK) · 1998
The pulsatile flow field in an anatomically realistic model of the bifurcation of the left anterior descending coronary artery (LAD) and its first diagonal branch (D1) was simulated numerically and measured by laser Doppler anemometry. The inlet velocity p ...
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Journal articleMedical Engineering & Physics · 1998
The susceptibility of vascular branches to atherosclerosis is believed to be due in part to the unusual fluid dynamic environments that the vessel wall experiences in these regions. As vascular geometry is a primary determinant of the local haemodynamic en ...
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Journal articleJ. Biomech. (UK) · 1998
The relationship between the geometry of branch points on the left anterior descending coronary artery, and the morphometry of the proximal portions of the daughter vessels, was examined. The geometry at 23 branch points on 15 human hearts was derived from ...
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Journal articleAmerican Society of Mechanical Engineers, Bioengineering Division (Publication) BED · 1997
Results are presented of a study on frequency dependence of arterial uptake of macromolecules in response to alternating shear levels. The experiments used an in vivo arteriovenous fistula preparation to modulate the wall shear stress in porcine iliac arte ...
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Journal articleAmerican Society of Mechanical Engineers, Bioengineering Division (Publication) BED · 1997
The geometry of the aortic bifurcation has drawn attention from several investigators. Notwithstanding the previous studies, the variability of the planarity of the aortic bifurcation has not been well described. This report discusses a study aimed to char ...
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Journal articleZ. Angew. Math. Mech. (Germany) · 1996
Pulsatile blood flow in anatomically correct models of arterial bifurcations is simulated numerically. The computational geometric models are developed on the basis of optically digitized casts. A finite element grid generation procedure based on optimizat ...
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Journal articleAmerican Society of Mechanical Engineers, Bioengineering Division (Publication) BED · 1996
The relationship between the geometry of branch points on the left anterior descending coronary artery, and the morphometry of the proximal portions of the daughter vessels, was examined. The geometry at 23 branch points on 15 human hearts was derived from ...
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Journal articleAmerican Society of Mechanical Engineers, Bioengineering Division (Publication) BED · 1996
A system was developed to track the position and curvature of the human coronary arteries during a cardiac cycle using bi-plane angiography. The system uses a time interpolation technique on one image plane to create simultaneous image pairs. The image pai ...
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Journal articleAmerican Society of Mechanical Engineers, Bioengineering Division (Publication) BED · 1995
Generally, the transport of macromolecules across the arterial endothelium, and their subsequent accumulation in the arterial wall is an important factor in the pathogenesis of atherosclerotic disease. It is hypothesized that endothelial permeability rises ...
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Journal articleAmerican Society of Mechanical Engineers, Bioengineering Division (Publication) BED · 1995
The localization of atherosclerosis, the progressive thickening and stiffening of arterial vessels is assumed to be influenced by hemodynamic mechanisms. Most hemodynamic mechanisms are influenced by local vascular geometry. Hence, the presence of such geo ...
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Journal articleTrans. ASME, J. Biomech. Eng. (USA) · 1995
A realistically compliant flow-through cast of a human aortic bifurcation was perfused with two almost identical physiological flow waves differing in pulsatile frequency. Near-wall fluid velocities were measured with a laser Doppler velocimeter at 14 site ...
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Journal articleAmerican Society of Mechanical Engineers, Bioengineering Division (Publication) BED · 1995
Pulsatile flow and wall shear stress in an anatomically correct model of a human left coronary artery segment is simulated numerically using the finite element method. The computational geometry model presenting a non-planar arterial branching is developed ...
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Journal articleAmerican Society of Mechanical Engineers, Bioengineering Division (Publication) BED · 1995
Porcine thoracoabdominal intimal surface patterns of transendothelial intimal-medial Evans blue dye-albumin (EBD-albumin) uptake were correlated with experimentally-imposed intimal surface shear stress vector fields in the well chambers of an in vitro arte ...
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Journal articleAmerican Society of Mechanical Engineers, Bioengineering Division (Publication) BED · 1995
Rigid injection cast of the left coronary arteries were photographed at multiple angles to provide images of the entire left main (LM), proximal portions of the left anterior descending (LAD) and the left circumflex (LCX) coronary arteries. Certain geometr ...
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Journal articleTrans. ASME, J. Biomech. Eng. (USA) · 1995
Image processing and computer numerical controlled (CNC) machining techniques have been used to prepare a larger-than-life investment cast of an aortic bifurcation from magnetic resonance images of a replica of the vessel. The technique will facilitate exp ...
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Journal articleAmerican Society of Mechanical Engineers, Bioengineering Division (Publication) BED · 1994
The 3-D, steady and pulsatile velocity fields and the corresponding endothelial shear stress fields that are created by a flow applicator in an organ support system have been calculated on a Cray Y-MP8/864 supercomputer using Version 4.2.3 of FLUENT, a com ...
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Journal articleAnn. Biomed. Eng. (USA) · 1994
A computer-based system is described to measure objectively the geometric parameters of arteries from pairs of projection angiograms. This technique, which employs back-projection to define the vessel axes in 3-D space, was used to obtain selected paramete ...
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Journal articleAmerican Society of Mechanical Engineers, Bioengineering Division (Publication) BED · 1994
A finite element grid generation procedure based on optimization of local grid properties has been developed using anatomically realistic data. The generator is especially suited in modeling of arterial bifurcation flow. The numerical procedure is applied ...
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Journal articleAnn. Biomed. Eng. (USA) · 1994
Presents a method for measuring arterial geometry in vivo using MRI. The approach was validated using MR images of three perfused compliant casts of human aortic bifurcations whose geometry was known. Preliminary human studies demonstrated the reproducibil ...
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Journal articleAmerican Society of Mechanical Engineers, Bioengineering Division (Publication) BED · 1993
This paper presents a method of measuring alterral geometry in vivo using MRI. The approach was validated using MR images of three perfused complaint casts of human aortic bifurcations whose geometry was known. Preliminary human studies demonstrated the re ...
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Journal articleAmerican Society of Mechanical Engineers, Bioengineering Division (Publication) BED · 1993
This paper evaluates steady-state Magnetic Resonance Imaging as a method to generate images depicting flow with low signal intensity for a wide range of velocities. Sixty or twenty eight cross-sectional images with 0.7-1 mm in-plane resolution were obtaine ...
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Journal articlePhys. Lett. B (Netherlands) · 1993
The potential energy of a static charge distribution on a lattice is rigorously computed in the standard compact quantum electrodynamic model. The method used follows closely that of Weyl for ordinary quantum electrodynamics in continuous spacetime. The po ...
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Journal articleTrans. ASME, J. Biomech. Eng. (USA) · 1993
Vascular flow models have been used more than any other means to gain insight into the details of arterial hemodynamics. The first flow models were not very realistic. The author's first attempt, was probably the most unrealistic of all: a “2D branch ...
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Journal articleTrans. ASME, J. Biomech. Eng. (USA) · 1992
A minimally diseased (mean intimal thickness=56 μm) human aortic bifurcation was replicated in rigid and compliant flow-through casts. Both casts were perfused with physiological flow waves having the same Reynolds and unsteadiness numbers; the pulse pr ...
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Journal articleAmerican Society of Mechanical Engineers, Bioengineering Division (Publication) BED · 1992
A compliant flow-through coronary cast and an in-vitro coronary flow system with physiologic flow were developed to evaluate, by comparison with laser Doppler anemometry (LDA), the capability of a 3F Millar steerable ultrasound Doppler catheter to provide ...
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Journal articleTrans. ASME, J. Biomech. Eng. (USA) · 1990
Rigid and complaint casts of a human aortic bifurcation were subjected to physiologically realistic pulsatile fluid flows. At a number of sites near the wall in the approximate median plane of the bifurcation of these models, fluid velocity was measured wi ...
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Journal articleAmerican Society of Mechanical Engineers, Bioengineering Division (Publication) BED · 1990
A realistically compliant flow-through cast of a human aortic bifurcation was perfused with two almost identical physiological flow waves differing in pulsatile frequency. Near-wall fluid velocities were measured with a laser Doppler velocimeter at 14 wall ...
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Journal articleJ. Biomech. (UK) · 1989
Shear rates measured at sites along the walls of ten casts of human aortic bifurcations are presented to provide an indication of the variability in the shear rate distribution that can occur among individuals. The geometric characteristics and flow parame ...
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Journal articleAmerican Society of Mechanical Engineers, Bioengineering Division (Publication) BED · 1988
Rigid and compliant casts of a human aortic bifurcation were subjected to physiologically realistic pulsatile fluid flows. At a number of sites near the wall in the plane of the bifurcation of these models, fluid velocity was measured with a laser Doppler ...
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Journal articleTrans. ASME, J. Biomech. Eng. (USA) · 1987
A variety of shear rate measures have been calculated from haemodynamic data obtained by laser Doppler anemometry in flow-through casts of human aortic bifurcations. Included are measures sensitive to the mean and amplitude of the shear rate, its maximum r ...
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Journal articleComputers in Cardiology · 1987
A technique has been developed to provide a 3-D, quantitative reconstruction of the coronary tree using axes extracted from two angiograms acquired at different angles. The reconstructed axes may be viewed from any perspective, even those normally unattain ...
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Journal articleJ. Phys. A, Math. Gen. (UK) · 1986
The nature of the bulk energy per unit volume in magneto-electric crystals implies an unusual form of Hall effect confined to the boundary surface crystal faces ...
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Journal articleTrans. ASME, J. Biomech. Eng. (USA) · 1986
Initial measurements of the time-varying wall shear rate at two sites in a compliant cast of a human aortic bifurcation are presented. The shear rates were derived from flow velocities measured by laser Doppler velocimetry (LDV) near the moving walls of th ...
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Journal articlePhys. Rev. B, Condens. Matter (USA) · 1985
In previous work, the concept of a quantized vortex was used to model the rational quantization of the Hall conductance for two-dimensional electronic systems. Here it is shown how the vortex model directly implies the concept of quantized magnetic inducti ...
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Journal articleTrans. ASME, J. Biomech. Eng. (USA) · 1985
This experiment was conducted to determine if the pulsatile flow through the proximal portion of the left coronary artery system in man exhibits quasi-steady characteristics. Steady and pulsatile flows were passed through an idealized model whose dimension ...
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Journal articleLett. Nuovo Cimento (Italy) · 1985
Some practical aspects of the chiral anomaly present in quantum electrodynamics are discussed in connection with the fractional Hall effect. The possibility that certain instabilities may develop is pointed out ...
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Journal articleAdvances in Bioengineering · 1985
This paper reports on a preliminary investigation that was carried out to develop experimental techniques which would enable the measurement of flow velocities in compliant arterial casts whose walls are in motion. A cast was made of an aortic bifurcation ...
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Journal articlePhys. Rev. B, Condens. Matter (USA) · 1985
The anomaly equation ∂μJ5μ=-(e2/8π2ℏ2c) (F*λσFλσ) is used to derive a relationship between the filling factor (ν) and the Hall conductance on the gate capacitor of a field-effect-transistor device. In addit ...
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Journal articlePhys. Rev. Lett. (USA) · 1985
The authors show that QED fluctuations for present metal-oxide-semiconductor field-effect transistor microcircuit devices are substantial and thus cannot be ignored. For example, the Casimir energy of a gate-region capacitor is typically 1/10 of the electr ...
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Journal articlePhys. Lett. A (Netherlands) · 1985
It is shown that the quantum electrodynamic chiral anomaly generates `spin waves' in the vacuum, when a low-energy electromagnetic field is applied. Such spin waves are (in principle) observable in a vacuum region with a condensed matter boundary surface w ...
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Journal articleComput. Fluids (UK) · 1985
The authors' investigation of bifurcation flows is extended to two-dimensional regions obtained from radiographs of human aortic bifurcations. These regions were mapped onto rectangles with a slit. Wall shapes were at first approximated using cubic splines ...
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Journal articleBiophys. J. (USA) · 1985
The unsteady response of the rabbit cornea to the normal periodic variations in tear tonicity which accompany the sleep-wake cycle is examined quantitatively in terms of a physical description of corneal mechanics and transport. Two different sets of exper ...
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Journal articleJ. Biomech. (UK) · 1984
In vivo radial strain measurements at the rabbit aortic bifurcation were made at different times during the cardiac cycle. At the peak of the pressure pulse, the radial strain at the bifurcation is positive in the plane perpendicular to the bifurcation but ...
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Journal articlePhys. Rev. Lett. (USA) · 1984
The quantum Hall effect is shown to be equivalent to a chiral anomaly i quantum electrodynamics. The integers n1 and n2 in the rationally quantized Hall conductance g=(e2/2πℏ)(n1/n2) arise from vortex excitations carrying n1 electrons and n2 flux ...
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Journal articlePhys. Rev. Lett. (USA) · 1984
Friedman et al. (see ibid, vol.52, p.1587 (1984)) proposed a model for the QHE involving the flow of charged vortices which carried a magnetic flux due to the Hall current generated by the electric field of the charge e*. They treated the electromagnetic f ...
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Journal articleJ. Biomech. (UK) · 1984
Two dimensional steady flow calculations in computational regions obtained from radiographs of human aortic bifurcations correlate well with unsteady measurements of wall shear in flow-through casts of the same vessels. The results suggests that wall slope ...
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Journal articleTrans. ASME, J. Biomech. Eng. (USA) · 1984
Steady and pulsatile flows were passed through casts of human aortic bifurcations and, by means of a laser Doppler anemometer, fluid velocities were measured at selected sites near the ventral and dorsal walls. At these sites, in the vicinity of the bifurc ...
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Journal articleJohns Hopkins APL Technical Digest (Applied Physics Laboratory) · 1983
It has been known for some time that the rate of developement of cardiovascular disease varies among individuals. It is proposed that some of this unexplained variability is due to corresponding variations in the detailed geometry of susceptible arterial s ...
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Journal articlePhys. Rev. D, Part. Fields (USA) · 1983
A model proposed by Aaron and Friedman (1982) is used to study q2q¯2 states. The results lead to speculations concerning the nature of the ε(1300) ...
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Journal articleJ. Phys. E, Sci. Instrum. (UK) · 1982
The fundamentals of ion motion in electromagnetic fields are reviewed in detail with a special emphasis on electric radio-frequency (RF) fields which are used frequently in dynamic mass spectrometry. Forces and effects on ions in electromagnetic fields whi ...
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Journal articleAm. J. Phys. (USA) · 1982
The inverted pendulum is shown to be an analog of the quadrupole mass filter. The theory of the inverted pendulum is developed and the design criteria for a working model are presented. The working model is used to experimentally measure the β paramet ...
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Journal articleJournal of Membrane Science · 1981
The measured flux of sucrose across Cuprophan dialysis membrane in the presence of a concentration gradient is significantly greater than the flux predicted from radioactive tracer permeabilities measured in the absence of a concentration gradient. The dif ...
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Journal articleBiophys. J. (USA) · 1981
The Kirkwood formulation of the Stefan-Maxwell equations is used to develop the transport equations for a membrane bounded by nonideal, nondilute solutions. The reflection coefficients for volume flow and solute flow are not equal but are related by a simp ...
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Journal articleTrans. ASME, J. Biomech. Eng. (USA) · 1981
A realistic pulsatile flow was passed through a cast of the aortic bifurcation of a 63-yr-old male with mild artherosclerosis, and a laser Doppler anemometer was used to measure fluid velocities in the cast at 15 selected sites near the lateral and medial ...
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Journal articleBiophys. J. (USA) · 1981
For pt.I see ibid., vol.34, p.535, 1981. The phenomenological solute permeability (ωp) of a membrane measures the flux of solute across it when the concentrations of the solutions on the two sides of the membrane differ. The relationship between &ome ...
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Journal articleTrans. ASME, J. Biomech. Eng. (USA) · 1980
A new approach is presented for studying the vascular response to hemodynamic stress. A laser doppler anemometer is used to make velocity measurements very near the walls of human arterial casts; these measurements are then correlated with the histology of ...
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Journal articlePhys. Rev. D, Part. Fields (USA) · 1980
Arguments are advanced for considering a particular Lagrangian in superspace. It is constructed solely from the connection associated with the graded group of real, general linear transformations, and is especially simple in form. The resulting equations o ...
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Journal articleAppl. Opt. (USA) · 1980
An additional modification is presented that allows velocity components to be measured in any direction in the plane perpendicular to the optical axis of the system. This is done by revolving the axis of the diffraction grating about the laser beam. The di ...
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Journal articleAmerican Society of Mechanical Engineers, Applied Mechanics Division, AMD · 1979
The distribution of atherosclerotic lesions in the large arteries strongly suggests that blood flow patterns (hemodynamics) adjacent to the vessel wall play a role in the development of the disease. The authors' approach has been to make hemodynamic measur ...
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Journal articleRadiat. Environ. Biophys. (West Germany) · 1979
Functional changes in the intestinal responsiveness to a fixed dose of acetylcholine were studied in muscle strips removed from young adult male rats previously exposed to whole body gamma radiation. In the irradiated rat the responsiveness to a fixed dose ...
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Journal articlePhys. Rev. D, Part. Fields (USA) · 1978
An affine theory of unified interactions is reviewed. Einstein's free gravitational equation emerges as a special case of the proposed equations of motion on superspace. For this example the vacuum is spontaneously broken to be globally Lorentz invariant. ...
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Journal articleJ. Radioanal. Chem. (Switzerland) · 1978
A program, written in FORTRAN, is described that defines a language MULTELMT for reducing activation analysis data. Communications are effected through commands, and these can be given in almost any order. Consistency checks are done and diagnostic message ...
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Journal articleTrans. Am. Nucl. Soc. (USA) · 1978
The main design features of MULTELMT (a computer language mnemonic: MULTiple ELeMenT), with emphasis on features not previously described. This language is written in FORTRAN V and is a translator rather than a compiler. Other analysts should find this lan ...
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Journal articlePhys. Rev. D, Part. Fields (USA) · 1977
Constructs the vacuum connection associated with a Yang-Mills theory of the graded Lie group of real linear transformations on superspace and discusses the obtained supersymmetric vacua. Shows that many of them lead to noninvertible vacuum metrics and/or t ...
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Journal articleIEEE Transactions on Biomedical Engineering · 1977
In a study of the development of atherosclerotic lesions, the authors investigate convective diffusion along the wall of a modeled arterial bifurcation. Under boundary layer assumptions, the resulting set of equations is transformed into a form to which La ...
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Journal articleJournal of Applied Mechanics, Transactions ASME · 1977
Velocity measurements are reported for steady and unsteady flow in a rectangular cross-section Y-branch of high aspect ratio. Good agreement is found between the experimental results and two-dimensional calculations. Emphasis is placed on flow velocities n ...
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Journal articlePhys. Rev. D, Part. Fields (USA) · 1977
Develops a formalism for imposing on superspace Yang-Mills local gauge invariance induced by general coordinate transformations. Shows that the construction of derivatives forces the introduction of a connection which is expected to be a function of all th ...
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Journal articleJ. Biomech. (UK) · 1977
In a study of the role of fluid mechanics in atherogenesis particle paths and stasis in a two-dimensional symmetric branch were examined, using the results of earlier fluid mechanical simulations of pulsatile blood flow to provide the velocity field. In re ...
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Journal articleIEEE Trans. Biomed. Eng. (USA) · 1977
In a study of the development of atherosclerotic lesions, the authors investigate convective diffusion along the wall of a modelled arterial bifurcation. Under boundary layer assumptions, the resulting set of equations is transformed into a form to which L ...
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Journal articleRev. Sci. Instrum. (USA) · 1977
A laser interferrometric technique has been used to follow the concentration difference across a membrane separating two fluid chambers. A constant pressure head is maintained across the membrane. The fluid volume in one chamber is monitored by measuring t ...
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Journal articleAIChE J. (USA) · 1976
The author discusses the flow past a surface which is permeable to the solute, when the interface boundary condition is complex and the variation along the wall of interfacial concentration or flux must in general be found by iterative numerical techniques ...
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Journal articleJ. Fluid Mech. (UK) · 1976
This study was motivated by the focal tendency of atherosclerotic plaque to appear near arterial junctions. A two-dimensional bifurcation was selected to provide preliminary information on branch flow dynamics. Superceding previous steady flow estimates in ...
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Journal articlePhys. Lett. B (Netherlands) · 1976
The suggestion that there exists an `internal parity' carried by the electron and μ-meson which is multiplicatively conserved is incorporated into a spontaneously broken gauge theory of the weak and electromagnetic interactions. The inclusion of hadrons ...
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Journal articleJ. Libr. Autom. (USA) · 1975
In 1897, as a special service to the blind, the Library of Congress established a small reading room stocked with approximately 500 books and music items in raised type. In 1974, a comprehensive internal study was begun by the Library of Congress Division ...
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Journal articleSpec. Libr. (USA) · 1975
The US Environmental Protection Agency's National Environmental Research Center in Cincinnati, Ohio, has set up a computerized service system following low-cost guidelines. The collection's catalog has been taped and literature searches are now available a ...
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Journal articleCirc. Res. (USA) · 1975
Numerical simulations of pulsatile blood flow through a symmetrical branch modeling the aortic bifurcation were carried out to assess several hemodynamic variables with that of early lesions in arterial branches. All of the proposed hemodynamic promoters o ...
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Journal articleCirc. Res. (USA) · 1975
The effect of spatially varying shear on transport to the wall of a two-dimensional branch was examined, using oxygen as the test solute and the results of earlier fluid mechanical calculations to provide the shear profiles in a region characterizing the a ...
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Journal articleAmerican Society of Mechanical Engineers, Applied Mechanics Division, AMD · 1975
The geometry and flow parameters of this experiment are chosen for this parallel plate model to be comparable to the hemodynamic situation in the human terminal abdominal aorta. Thus the experimental Reynolds numbers, based on channel half-width and the av ...
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Journal articlePhys. Rev. D, Part. Fields (USA) · 1975
The invariance of the gravitational theory of Einstein under general coordinate transformations was demonstrated to be equivalent to invariance under local gauge transformations of the group GL(4,R) by Yang (see Phys. Rev. Lett., vol.33, p.445 (1974)). Thi ...
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Journal articlePhys. Rev. D, Part. Fields (USA) · 1973
The authors reproduce the full content of the Fritzsch-Gell-Mann light-cone algebra (originally derived using the quark model) for deep-inelastic lepton-nucleon scattering using currents given by the field-current identity. These currents are modified by d ...
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Journal articleAPL Tech. Dig. (USA) · 1972
The mechanisms by which the normal cornea maintains its thickness and hence its transparency in vivo are elucidated by an unsteady-state description of corneal mass transport. All modes of transport, diffusion and convection of solute, hydraulic and osmoti ...
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Journal articlePhys. Lett. B (Netherlands) · 1972
Currents of scale dimension 3 of the field-current identity type arise naturally from the principles of broken scale invariance. Applications at intermediate energy to e++e- annihilation into four charged pions, and at high energy to light cone commutators ...
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Journal articlePhys. Rev. D, Part. Fields (USA) · 1971
Hard-meson techniques are presented for calculating processes involving octets (nonets) of mesons under the assumptions of chiral SU(3)×SU(3) [U(3)×U(3)] current-algebra commutation relations, partial conservation of axial-vector current, conse ...
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Journal articleNuovo Cimento A (Italy) · 1971
The assumption of π, η and σ dominance of the weak and electromagnetic decays of the K-meson is examined using the hard- meson current algebra amplitudes for the strong-interaction factors. The K→3π decay spectrum, the KL0→2&gamma ...
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Journal articlePhys. Rev. Lett. (USA) · 1971
Using hard-meson current algebra with single meson dominance of currents and the σ commutator, it is deduced that the 0± mesons must occur in nonets, and chiral symmetry is broken by only (3,3*)⊕(3*,3) terms (which then implies a small & ...
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Journal articleNucl. Phys. B (Netherlands) · 1971
A simple Lagrangian is constructed, which in the tree approximation produces a ππ scattering amplitude possessing (i) the correct iso-spin structure with no exotic resonances (ii) Regge asymptotic behavior Sαρ(t) and (iii) duality and satis ...
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Journal articleNature (UK) · 1971
A computer model of the cornea has been used to examine the implications of measurements of the variation of the short-circuit current of the isolated rabbit cornea as the sodium content of the media bathing both the epithelial and endothelial surfaces is ...
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Journal articlePhys. Rev. D, Part. Fields (USA) · 1971
A general analysis is given of the interaction of mesons of JP=0±, 1±, and 2+ obeying the principles of broken scale invariance in the tree and seagull approximations. Broken scale invariance is introduced through a new postulate which requir ...
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Journal articlePhys. Rev. D, Part. Fields (USA) · 1970
The possibility is examined of extending the ππ→ππ and πA1→ππ Veneziano amplitudes to the case of one or two mesons off the mass shell in a fashion consistent with chiral current algebra, partial conservation of axial-vector ...
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Journal articlePhys. Rev. Lett. (USA) · 1970
A general representation for scattering amplitudes is proposed which is crossing symmetric, satisfies Regge behaviour and duality, and possesses double spectral functions. As the width parameter goes to zero, the resonance poles on the second sheet move on ...
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Journal articlePhys. Rev. Lett. (USA) · 1969
Hard-meson partial conservations of axial-vector and partial conservation of vector current are imposed upon the Veneziano amplitudes. It is seen that these determine inelastic amplitudes (e.g., ππ→πA1, etc.) in terms of corresponding elastic ...
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Journal articleNucl. Phys. B (Netherlands) · 1969
A hard-meson calculation of the Kl3, K* and κ decays is given based upon (i) chiral SU(3)×SU(3) current algebra, (ii) pion and kaon PCAC, (iii) single meson saturation, (iv) approximation of meson vertices by low-order polynomials in momentum ...
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Journal articleCombust. Flame (USA) · 1969
A thermal explosion criterion recently published by the author (see ibid., vol.11, 239 of 1967) is used to obtain general solutions for the explosion/ignition delay of an exothermic material surrounding a heated wire which is long and a good thermal conduc ...
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Journal articlePhys. Rev. (USA) · 1968
Application of hard-pion four-point functions is made to ππ scattering on the basis of the SU(2)×SU(2) current algebra, a conserved vector current, a partially conserved axial-vector current, and the hypothesis of single-meson dominance of inte ...
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Journal articleNuclear Physics · 1968
The derivations of gρ2 = 2Fπ2mρ2 by Kawarabayashi and Suzuki (Abstr. 1966A26144) and others are re-examined. When the full content of chiral algebra is exploited, the analysis reduces to an identity rather than a determination of gρ. (15 Ref ...
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Journal articlePhys. Rev. (USA) · 1968
Hard-pion techniques are presented for calculating T products of an arbitrary number of vector and axial-vector currents under the assumptions of single σ-.π-,ρ-, and A1 meson saturation of intermediate sums, chiral SU(2)×SU (2)-algebra ...
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Journal articlePhys. Rev. (USA) · 1968
Hard-pion techniques are presented for calculating vertex functions involving π,ρ,A1, and σ mesons. The development of the method involves the following assumptions: (a) saturation of intermediate sums by single mesons, (b) chiral SU(2)× ...
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Journal articlePhysical Review Letters · 1968
A mass-shell current-algebra calculation of π-π scattering is given. The Weinberg scattering lengths and effective ranges are shown to be valid within a few percent. At the K meson mass, we find the essentially model-independent result δ0-&delt ...
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Journal articlePhys. Rev. (USA) · 1968
Some comparisons with experiment of the hard-pion three- point functions obtained from SU(2)×SU(2) current algebra are given. Available experimental data involving π,ρ, A1, and σ mesons are examined. The hard-pion current-algebra method ...
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Journal articlePhysical Review Letters · 1967
A method is given for calculating vertex functions involving three currents obeying chiral SU(2) ⊗ SU(2) commutation relations, without using soft-pion approximations. The procedure assumes one-particle dominance of intermediate states. The Weinberg ...
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Journal articlePhysical Review · 1967
A technique is presented for treating a general type of three-body bound-state problem for situations where the interaction may be written as the sum of three pair potentials. The method is based on the work of Eyges and consists of writing the total wave ...
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Journal articleCombustion and Flame · 1967
Generalized thermal explosion criterion is presented, based on inert and adiabatic solutions to sensitivity equation; algorithm can be used to find critical conditions and explosion delays for many thermal explosion problems; technique is applied in illust ...
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Journal articleAIAA Journal · 1966
Virial equation of state is used to derive solutions for detonation velocity and pressure of explosives; detonation parameters are defined by energy of detonation, loading density, average number of atoms per gaseous product molecule, weight fraction solid ...
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Journal articleCombustion and Flame · 1966
A shock tube test is described, in which fine dusts or sprays of explosive materials are ignited behind the reflected shock, and the dependence of the measured ignition delay on reflected shock temperature is determined. The test simulates the impact initi ...
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Journal articleCombustion Institute -- Paper · 1965
Shock tube test is described in which fine dusts or sprays of explosive materials are ignited behind reflected shock, and dependence of measured ignition delay on reflected shock temperature is determined; test simulates impact initiation of liquids and so ...
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Journal articleNuovo Cimento B · 1965
A variational procedure due to Husimi (1940) is applied to the many-boson problem in an effort to find an approximate density matrix. The results are identical to those previously obtained by Wentzel (1960) employing another technique. It differs primarily ...
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Journal articlePhysical Review · 1965
A soluble model of a Bose - Einstein system is examined, in which the interaction energy between particles is attractive as the momentum approaches zero. The model is based on one proposed by Bassichis and Foldy. ...
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Journal articleFaraday Society -- Transactions · 1963
Research based on work relating to solid propellants; hot spot is represented by mathematical model as rectangular temperature spike in infinitely large sample of reactant; consequent differential equation is integrated numerically and results are correlat ...
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Journal articleAmerican Chemical Society -- Division of Fuel Chemistry -- Papers · 1963
Method of predicting Chapman-Jouguet detonation characteristics, has been developed; gaseous explosion products are assumed to obey virial equation of state; analysis predicts detonation pressure as well as, or better than, solutions based on Abel or Kisti ...
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Journal articleHeating, Piping and Air Conditioning · 1959
Protective system at US Military Academy, West Point, NY, which is not affected by power failures; system consists of separate scanner for each burner which operates through control panel to close individual fuel valve, light its respective pilot and sound ...
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Journal articlePhysical Review · 1957
Remarks that the experimental values of the Michel parameter (ρ) and the back - front (B/F) ratio for decay electrons between 0 and 10 MeV seem inconsistent with predictions of the two-component theory assuming the decay process: μ→ e+ν+ν ...
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Journal articlePhysical Review · 1956
A fixed-source analysis of the s-wave pion -nucleon interaction is constructed along the lines of the Chew-Low-Wick formalism. A bilinear s-wave interaction of the form λ0φ.φ+λτ.(φ×pi;) is added to the usual p-wave coupl ...
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Journal articlePhysical Review · 1955
An intermediate-coupling method of calculation is applied to the meson-nucleon scattering problem for the case of symmetric pseudoscalar mesons, coupled to a fixed extended source through derivative coupling. It is found that the experimentally observed P- ...
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Journal articleTrans. Am. Nucl. Soc. (USA) · 1955
A system is described, based on a multiple element language MTELMT which can automatically search a spectrum, find the resolved peaks, and output the energies and areas of the peaks; make linear or semilogarithmic CAL COMP plots; and provide an accurate en ...
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Journal articlePhysical Review · 1955
The ground-state solution of the physical nucleon problem in the Tomonaga approximation is used to compute the anomalous magnetic moment of nucleons. When computed on the basis of parameters that make the phase-shift calculations in the Tomonaga approximat ...
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Journal articlePhysical Review · 1955
The anomalous magnetic moments of the neutron and proton are calculated to fourth order by using a cut-off meson theory. The value obtained is 1.44 when one uses the same parameters as employed for fitting the meson-nucleon scattering data. ...
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Journal articlePhysical Review · 1955
It is shown by a rigorous development from first principles that a relatively simple form for the partition function of an imperfect Bose-Einstein gas can be obtained. This form is that of a 3N-dimensional integral (N being the total number of particles) t ...
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Journal articlePhys. Rev. D, Part. Fields (USA)
The authors develop an approach for introducing bosons into gauge theories as composite states of fermions. It is scale and gauge invariant from the outset and utilizes invariant regularization procedures. This results in the acquisition of gauge-covariant ...
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Journal articleJ. Phys. G, Nucl. Part. Phys. (UK)
We consider fermions in a constant and uniform external SU(2) magnetic field. We find that the results for the energy levels depend on the choice of gauge. Choosing a Landau-type gauge yields results analagous to those of Abelian theories. On the other han ...
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Journal articlePhys. Essays (Canada)
We use the constraint imposed by Gauss's law to argue that the color charged states of SU(3) [quantum chromodynamics (QCD)] are not physical. We further show that the matrix elements of products of gluon field and quark current operators at different space ...
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