ConferenceJournal of Clinical Oncology · February 1, 2024
262Background: Stockholm3 is a multiparametric blood test incorporating germline risk, proteins and clinical data which improves prostate cancer (PC) risk stratification compared to PSA, however no validation exists in an ethnically diverse population. Met ...
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ConferenceJournal of Clinical Oncology · February 20, 2021
328 Background: Anti-PD1/PDL1 immune checkpoint inhibition (CPI) is active in advanced clear cell RCC, but not all patients benefit. Preclinical studies with the combination of hypomethylating agents and CPI resulted in reversal ...
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ConferenceCancer Epidemiology, Biomarkers & Prevention · June 1, 2020
AbstractIntroduction: The low specificity of PSA in prostate cancer (PCa) screening has caused excessive biopsies and PCa over-detection. PHI is more specific for clinically significant (cs) PCa (i.e. Gleaso ...
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ConferenceCancer Epidemiology, Biomarkers & Prevention · June 1, 2020
AbstractThe Oncotype DX Prostate Cancer Assay® (ODX), a 17-gene expression profile performed on biopsy tissue, has been validated for prediction of adverse pathology at surgery and 10-year risk of metastasis ...
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ConferenceUrol Oncol · July 2015
PURPOSE: To investigate the association between Agent Orange (AO) exposure and long-term prostate cancer (PC) outcomes. MATERIAL AND METHODS: Data from 1,882 men undergoing radical prostatectomy for PC between 1988 and 2011 at Veterans Affairs Health Care ...
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ConferenceCancer Research · April 15, 2012
AbstractIntroduction: Preclinical studies have shown that dietary carbohydrate restriction slows prostate tumor growth in multiple xenograft models in part due to a reduction insulin-like growth factor (IGF) ...
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ConferenceCancer Research · April 15, 2012
AbstractIntroduction: Methionine restriction has been shown to have growth inhibitory effects in a number of tumor cell lines in vitro. Methionine restriction has previously been demonstrated to slow PC-3 pr ...
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