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Michael D Deel

Assistant Professor of Pediatrics
Pediatrics, Hematology-Oncology
Duke University, Box 102382, Durham, NC 27710
Duke University Medical Center, Box 102382, Durham, NC 27710


Dr. Deel is a clinician scientist in Pediatric Hematology/Oncology. In addition to caring for pediatric patients with hematologic disorders or malignancy, his research focuses on finding novel ways to target fusion-positive pediatric sarcomas. His current work focuses on understanding the gene regulation and molecular pathways responsible for alveolar rhabdomyosarcoma, which is among the most difficult to cure pediatric cancers. Alveolar rhabdomyosarcoma is driven by chromosomal translocations t(2;13) or t(1;13) that result in oncogenic transcription factors encoding for PAX3/7-FOXO1 fusion proteins. The PAX3/7-FOXO1 oncogenes are currently not viable therapeutic targets. Using a variety of cell culture and murine models, Dr. Deel is investigating genes and pathways that regulate or coordinate PAX3/7-FOXO1-mediated tumorigenesis.

Current Appointments & Affiliations

Assistant Professor of Pediatrics · 2021 - Present Pediatrics, Hematology-Oncology, Pediatrics
Member of the Duke Cancer Institute · 2018 - Present Duke Cancer Institute, Institutes and Centers

Education, Training & Certifications

Marshall University, Joan C. Edwards School of Medicine · 2010 M.D.