Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Fellow in Cardiology, Medicine, Duke University 1999 - 2002
  • Fellow in Cardiology, Medicine, Johns Hopkins University 1998 - 1999
  • Assistant Chief of Service, Medicine, Johns Hopkins University 1997 - 1998
  • Faculty, Medicine, Union Memorial Hospital 1996 - 1997
  • Medical Resident, Medicine, Johns Hopkins University 1993 - 1996
  • M.D., Duke University 1993
• 

  Previous Appointments & Affiliations

  • Professor of Medicine, Medicine, Cardiology, Medicine 2014 - 2020
  • Associate Professor of Medicine, Medicine, Cardiology, Medicine 2012 - 2014
  • Associate Professor of Medicine, Medicine, Cardiology, Medicine 2008 - 2012
  • Assistant Professor of Medicine, Medicine, Cardiology, Medicine 2002 - 2008
• Research
• 

  Selected Grants

  • Congestion Phenotypes and Splanchnic Nerve Modulation in Chronic Heart Failure awarded by National Institutes of Health 2020 - 2025
  • Role of the Splanchnic Vascular Compartment in Heart Failure with Preserved Ejection Fraction awarded by Doris Duke Charitable Foundation, Inc. 2022 - 2025
  • MK1242-035-CEC awarded by Merck & Co., Inc. 2021 - 2025
  • Use and Effectiveness of Outpatient Intravenous Diuretic Therapy as Treatment for Worsening Heart Failure awarded by  American Heart Association 2022 - 2025
  • Plasmonically Enhanced Point-of-care Detection of Cardiac Biomarkers by a Smart Phone awarded by National Institutes of Health 2019 - 2024
  • Postdoctoral Training in Cardiovascular Clinical Research awarded by National Institutes of Health 2013 - 2024
  • Mavacamten Manuscripts awarded by Bristol-Myers Squibb Company 2021 - 2023
  • PARACOR-19 awarded by Novartis Pharmaceuticals Corporation 2021 - 2023
  • Multidisciplinary Heart and Vascular Diseases awarded by National Institutes of Health 1975 - 2023
  • The Feasibility of a Biomarker Guided Strategy in Anthracycline Cardiotoxicity awarded by University of Pennsylvania 2020 - 2022
  • Characterization of Patients with Heart Failure and Patients with Vascular Disease and Atrial Fibrillation in Duke University Health System Data awarded by Bayer Corporation 2020 - 2022
  • DAXOR - BVA Trial awarded by Daxor Corporation 2020 - 2021
  • A Double-blind, Randomized, Placebo-controlled, Multicenter Study to Assess the Efficacy and Safety of Omecamtiv Mecarbil on Mortality and Morbidity in Subjects with Chronic Heart Failure with Reduced awarded by Amgen, Inc. 2016 - 2021
  • HF Clinical Research Network Regional Clinical Center (U10) awarded by National Institutes of Health 2012 - 2020
  • INDIE-HF-pEF awarded by Aries Pharmaceuticals 2016 - 2019
  • GDF-15 FIGHT/RD003507 awarded by Roche Diagnostics 2018 - 2019
  • Functional Impact of GLP-1 for Heart Failure Treatment awarded by National Heart, Lung, and Blood Institute 2006 - 2018
  • ATHENA-HF awarded by National Institutes of Health 2014 - 2018
  • Oral Iron Repletion effects on Oxygen Uptake in Heart Failure awarded by National Institutes of Health 2014 - 2018
  • NEAT awarded by National Institutes of Health 2006 - 2018
  • CardioMEMS awarded by Pacesetter, Inc. 2016 - 2018
  • GUIDing Evidence Based Therapy Using Biomarker Intensified Treatment (CCC) awarded by National Institutes of Health 2012 - 2018
  • GUIDing Evidence Based Therapy Using Biomarker Intensified Treatment (CCC) awarded by National Institutes of Health 2012 - 2017
  • Promotion of Renal Sodium Excretion by Renal Sympathetic Denervation in Congestive Heart Failure awarded by Medtronic, Inc. 2014 - 2015
  • DOSE Protocol awarded by National Institutes of Health 2008 - 2011
  • RELAX awarded by National Institutes of Health 2008 - 2011
  • Pharmacometabolomics Research Network awarded by National Institutes of Health 2010 - 2011
  • Inflammation & Prognosis in Decompensated Heart Failure awarded by National Institutes of Health 2004 - 2010
• 

  External Relationships

  • Abbott (St. Jude Medical)
  • Amgen, Inc.
  • Boehringer Ingleheim
  • Bristol-Myers Squibb
  • Cardionomic
  • Cytokinetics, Inc.
  • EBR Systems
  • LivaNova
  • Medtronic Foundation
  • Novartis
  • Rocket Pharma
  • Sequana
  • Siemens
  • american regent
  • innolife
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Felker, G Michael, Peter Buttrick, Anthony Rosenzweig, E Dale Abel, Larry A. Allen, Michael Bristow, Saumya Das, et al. “Heart Failure Strategically Focused Research Network: Summary of Results and Future Directions.” J Am Heart Assoc 11, no. 18 (September 20, 2022): e025517. https://doi.org/10.1161/JAHA.122.025517.
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    • Myhre, Peder L., Margaret F. Prescott, Brian Claggett, G Michael Felker, Javed Butler, Ileana L. Piña, Alan S. Maisel, et al. “Comparative Effect of Angiotensin Receptor Neprilysin Inhibition on B-type Natriuretic Peptide Levels Measured by Three Different Assays: The PROVE-HF Study.” Clin Chem, September 14, 2022. https://doi.org/10.1093/clinchem/hvac148.
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    • Khan, Muhammad Shahzeb, G Michael Felker, and Marat Fudim. “Are We Getting Any Closer to Understanding Congestion?” Jacc Heart Fail 10, no. 9 (September 2022): 633–36. https://doi.org/10.1016/j.jchf.2022.06.008.
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    • Felker, G Michael. “New Decongestion Strategies in an Evolving Heart Failure Landscape.” N Engl J Med, August 27, 2022. https://doi.org/10.1056/NEJMe2209997.
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    • Harrington, Josephine, G Michael Felker, and Robert J. Mentz. “Catastrophic Disruptions in Clinical Trials.” Circulation 146, no. 5 (August 2, 2022): 369–71. https://doi.org/10.1161/CIRCULATIONAHA.122.060541.
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    • Granger, Bradi B., Lisa A. Kaltenbach, Gregg C. Fonarow, Larry A. Allen, David E. Lanfear, Nancy M. Albert, Hussein R. Al-Khalidi, et al. “Health System-Level Performance in Prescribing Guideline-Directed Medical Therapy for Patients With Heart Failure With Reduced Ejection Fraction: Results From the CONNECT-HF Trial.” J Card Fail 28, no. 8 (August 2022): 1355–61. https://doi.org/10.1016/j.cardfail.2022.03.356.
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    • Felker, G Michael, Abhinav Sharma, Robert J. Mentz, Lilin She, Cynthia L. Green, Bradi B. Granger, John F. Heitner, et al. “A Randomized Controlled Trial of Mobile Health Intervention in Patients With Heart Failure and Diabetes.” J Card Fail, July 23, 2022. https://doi.org/10.1016/j.cardfail.2022.07.048.
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    • Lewis, Gregory D., Adriaan A. Voors, Alain Cohen-Solal, Marco Metra, David J. Whellan, Justin A. Ezekowitz, Michael Böhm, et al. “Effect of Omecamtiv Mecarbil on Exercise Capacity in Chronic Heart Failure With Reduced Ejection Fraction: The METEORIC-HF Randomized Clinical Trial.” Jama 328, no. 3 (July 19, 2022): 259–69. https://doi.org/10.1001/jama.2022.11016.
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    • Solomon, Scott D., Brian L. Claggett, Zi Michael Miao, Rafael Diaz, G Michael Felker, John J. V. McMurray, Marco Metra, et al. “Influence of atrial fibrillation on efficacy and safety of omecamtiv mecarbil in heart failure: the GALACTIC-HF trial.” Eur Heart J 43, no. 23 (June 14, 2022): 2212–20. https://doi.org/10.1093/eurheartj/ehac144.
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    • Lerman, Joseph B., Stephanie N. Giamberardino, Adrian F. Hernandez, G Michael Felker, Svati H. Shah, and Robert W. McGarrah. “Plasma metabolites associated with functional and clinical outcomes in heart failure with reduced ejection fraction with and without type 2 diabetes.” Sci Rep 12, no. 1 (June 2, 2022): 9183. https://doi.org/10.1038/s41598-022-12973-0.
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    • Metra, Marco, Matteo Pagnesi, Brian L. Claggett, Rafael Díaz, G Michael Felker, John J. V. McMurray, Scott D. Solomon, et al. “Effects of omecamtiv mecarbil in heart failure with reduced ejection fraction according to blood pressure: the GALACTIC-HF trial.” Eur Heart J, May 22, 2022. https://doi.org/10.1093/eurheartj/ehac293.
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    • Razaghizad, Amir, Emily Oulousian, Varinder Kaur Randhawa, João Pedro Ferreira, James M. Brophy, Stephen J. Greene, Julian Guida, et al. “Clinical Prediction Models for Heart Failure Hospitalization in Type 2 Diabetes: A Systematic Review and Meta-Analysis.” J Am Heart Assoc 11, no. 10 (May 17, 2022): e024833. https://doi.org/10.1161/JAHA.121.024833.
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    • Khan, Muhammad Shahzeb, Adam D. DeVore, G Michael Felker, Javed Butler, Gregg C. Fonarow, and Stephen J. Greene. “Reply: Revisited Metformin Therapy in Heart Failure With Preserved Ejection Fraction.” Jacc Heart Fail 10, no. 5 (May 2022): 366–67. https://doi.org/10.1016/j.jchf.2022.02.013.
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    • Lewis, Gregory D., Kieran F. Docherty, Adriaan A. Voors, Alain Cohen-Solal, Marco Metra, David J. Whellan, Justin A. Ezekowitz, et al. “Developments in Exercise Capacity Assessment in Heart Failure Clinical Trials and the Rationale for the Design of METEORIC-HF.” Circ Heart Fail 15, no. 5 (May 2022): e008970. https://doi.org/10.1161/CIRCHEARTFAILURE.121.008970.
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    • Rao, Vishal N., Jennifer Andrews, Willard N. Applefeld, James M. Gray, Jeroen Molinger, G Michael Felker, Wayne L. Miller, Manesh R. Patel, Adrian F. Hernandez, and Marat Fudim. “Quantitative Blood Volume Analysis and Hemodynamic Measures of Vascular Compliance in Patients With Worsening Heart Failure.” J Card Fail, April 26, 2022. https://doi.org/10.1016/j.cardfail.2022.04.004.
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    • Khan, Muhammad Shahzeb, Matthew W. Segar, Muhammad Shariq Usman, Sumitabh Singh, Stephen J. Greene, Gregg C. Fonarow, Stefan D. Anker, et al. “Frailty, Guideline-Directed Medical Therapy, and Outcomes in HFrEF: From the GUIDE-IT Trial.” Jacc Heart Fail 10, no. 4 (April 2022): 266–75. https://doi.org/10.1016/j.jchf.2021.12.004.
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    • Carnicelli, Anthony P., Robert M. Clare, Paul Hofmann, Karen Chiswell, Adam D. DeVore, Sreekanth Vemulapalli, G Michael Felker, et al. “Clinical trajectory of patients with a worsening heart failure event and reduced ventricular ejection fraction.” Am Heart J 245 (March 2022): 110–16. https://doi.org/10.1016/j.ahj.2021.12.003.
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    • Khan, Muhammad Shahzeb, Nicole Solomon, Adam D. DeVore, Abhinav Sharma, G Michael Felker, Adrian F. Hernandez, Paul A. Heidenreich, et al. “Clinical Outcomes With Metformin and Sulfonylurea Therapies Among Patients With Heart Failure and Diabetes.” Jacc Heart Fail 10, no. 3 (March 2022): 198–210. https://doi.org/10.1016/j.jchf.2021.11.001.
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    • Pahuja, Mohit, Eric S. Leifer, John-Ross D. Clarke, Tariq Ahmad, Melissa A. Daubert, Daniel B. Mark, Lawton Cooper, et al. “Assessing race and ethnicity differences in outcomes based on GDMT and target NT-proBNP in patients with heart failure with reduced ejection fraction: An analysis of the GUIDE-IT study.” Prog Cardiovasc Dis 71 (March 2022): 79–85. https://doi.org/10.1016/j.pcad.2022.04.010.
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    • Zeitler, Emily P., and G Michael Felker. “Natriuretic Peptides and Stratification for ICD Therapy in Nonischemic Heart Failure: A Definite Maybe?” Jacc Heart Fail 10, no. 3 (March 2022): 172–74. https://doi.org/10.1016/j.jchf.2022.01.007.
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    • Emmens, Johanna E., Jozine M. Ter Maaten, Yuya Matsue, Sylwia M. Figarska, Iziah E. Sama, Gad Cotter, John G. F. Cleland, et al. “Worsening renal function in acute heart failure in the context of diuretic response.” Eur J Heart Fail 24, no. 2 (February 2022): 365–74. https://doi.org/10.1002/ejhf.2384.
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    • Ezekowitz, Justin A., Wendimagegn Alemayehu, Sarah Rathwell, Andrew D. Grant, Mona Fiuzat, David J. Whellan, Tariq Ahmad, et al. “The influence of comorbidities on achieving an N-terminal pro-b-type natriuretic peptide target: a secondary analysis of the GUIDE-IT trial.” Esc Heart Fail 9, no. 1 (February 2022): 77–86. https://doi.org/10.1002/ehf2.13692.
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    • Harrington, Josephine, and G Michael Felker. “Leveraging Multiple Biomarkers to Assess Risk of Acute Heart Failure: Is More Better?” J Card Fail 28, no. 2 (February 2022): 234–36. https://doi.org/10.1016/j.cardfail.2021.11.015.
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    • Felker, G Michael, Scott D. Solomon, Brian Claggett, Rafael Diaz, John J. V. McMurray, Marco Metra, Inder Anand, et al. “Assessment of Omecamtiv Mecarbil for the Treatment of Patients With Severe Heart Failure: A Post Hoc Analysis of Data From the GALACTIC-HF Randomized Clinical Trial.” Jama Cardiol 7, no. 1 (January 1, 2022): 26–34. https://doi.org/10.1001/jamacardio.2021.4027.
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    • Mann, Douglas L., Michael M. Givertz, Justin M. Vader, Randall C. Starling, Palak Shah, Steven E. McNulty, Kevin J. Anstrom, et al. “Effect of Treatment With Sacubitril/Valsartan in Patients With Advanced Heart Failure and Reduced Ejection Fraction: A Randomized Clinical Trial.” Jama Cardiol 7, no. 1 (January 1, 2022): 17–25. https://doi.org/10.1001/jamacardio.2021.4567.
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    • Chouairi, Fouad, Michael A. Fuery, Clancy W. Mullan, Cesar Caraballo, Sounok Sen, Christopher Maulion, Samuel T. Wilkinson, et al. “The Impact of Depression on Outcomes in Patients With Heart Failure and Reduced Ejection Fraction Treated in the GUIDE-IT Trial.” J Card Fail 27, no. 12 (December 2021): 1359–66. https://doi.org/10.1016/j.cardfail.2021.06.008.
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    • Matsue, Yuya, Iziah E. Sama, Douwe Postmus, Marco Metra, Barry H. Greenberg, Gad Cotter, Beth A. Davison, et al. “Association of Early Blood Pressure Decrease and Renal Function With Prognosis in Acute Heart Failure.” Jacc Heart Fail 9, no. 12 (December 2021): 890–903. https://doi.org/10.1016/j.jchf.2021.07.001.
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    • Greenberg, Barry, Christopher M. O’Connor, and G Michael Felker. “Classifying Heart Failure in the 21st Century: Matching Taxonomy With Science.” Jacc Heart Fail 9, no. 10 (October 2021): 771–73. https://doi.org/10.1016/j.jchf.2021.08.004.
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    • Fudim, Marat, Toi Spates, Jie-Lena Sun, Veraprapas Kittipibul, Jeffrey M. Testani, Randall C. Starling, WH Wilson Tang, et al. “Early diuretic strategies and the association with In-hospital and Post-discharge outcomes in acute heart failure.” Am Heart J 239 (September 2021): 110–19. https://doi.org/10.1016/j.ahj.2021.05.011.
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    • Ibrahim, Nasrien E., and G Michael Felker. “Don't Be So Fast to Discard That Clean Catch!.” Jacc Heart Fail 9, no. 9 (September 2021): 624–26. https://doi.org/10.1016/j.jchf.2021.05.015.
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    • Truby, Lauren K., Jessica A. Regan, Stephanie N. Giamberardino, Olga Ilkayeva, James Bain, Christopher B. Newgard, Christopher M. O’Connor, et al. “Circulating long chain acylcarnitines and outcomes in diabetic heart failure: an HF-ACTION clinical trial substudy.” Cardiovasc Diabetol 20, no. 1 (August 3, 2021): 161. https://doi.org/10.1186/s12933-021-01353-z.
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    • Sharma, Abhinav, Stephen Greene, Muthiah Vaduganathan, Marat Fudim, Andrew P. Ambrosy, Jie-Lena Sun, Steven E. McNulty, et al. “Growth differentiation factor-15, treatment with liraglutide, and clinical outcomes among patients with heart failure.” Esc Heart Fail 8, no. 4 (August 2021): 2608–16. https://doi.org/10.1002/ehf2.13348.
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    • DeVore, Adam D., Bradi B. Granger, Gregg C. Fonarow, Hussein R. Al-Khalidi, Nancy M. Albert, Eldrin F. Lewis, Javed Butler, et al. “Effect of a Hospital and Postdischarge Quality Improvement Intervention on Clinical Outcomes and Quality of Care for Patients With Heart Failure With Reduced Ejection Fraction: The CONNECT-HF Randomized Clinical Trial.” Jama 326, no. 4 (July 27, 2021): 314–23. https://doi.org/10.1001/jama.2021.8844.
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    • Felker, G Michael, Javed Butler, Nasiren E. Ibrahim, Ileana L. Piña, Alan Maisel, Devavrat Bapat, Alexander Camacho, et al. “Implantable Cardioverter-Defibrillator Eligibility After Initiation of Sacubitril/Valsartan in Chronic Heart Failure: Insights From PROVE-HF.” Circulation 144, no. 2 (July 13, 2021): 180–82. https://doi.org/10.1161/CIRCULATIONAHA.121.054034.
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    • Teerlink, John R., Rafael Diaz, G Michael Felker, John J. V. McMurray, Marco Metra, Scott D. Solomon, Tor Biering-Sørensen, et al. “Effect of Ejection Fraction on Clinical Outcomes in Patients Treated With Omecamtiv Mecarbil in GALACTIC-HF.” J Am Coll Cardiol 78, no. 2 (July 13, 2021): 97–108. https://doi.org/10.1016/j.jacc.2021.04.065.
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    • Girerd, Nicolas, and G Michael Felker. “The lower is not always the better: a more comprehensive understanding of loop diuretics in heart failure.” Eur J Heart Fail 23, no. 7 (July 2021): 1120–21. https://doi.org/10.1002/ejhf.2182.
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    • Lang, Ninian N., Faheem A. Ahmad, John G. Cleland, Christopher M. O’Connor, John R. Teerlink, Adriaan A. Voors, Jorg Taubel, et al. “Haemodynamic effects of the nitroxyl donor cimlanod (BMS-986231) in chronic heart failure: a randomized trial.” Eur J Heart Fail 23, no. 7 (July 2021): 1147–55. https://doi.org/10.1002/ejhf.2138.
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    • Fudim, Marat, Piotr P. Ponikowski, Daniel Burkhoff, Mark E. Dunlap, Paul A. Sobotka, Jeroen Molinger, Manesh R. Patel, et al. “Splanchnic nerve modulation in heart failure: mechanistic overview, initial clinical experience, and safety considerations.” Eur J Heart Fail 23, no. 7 (July 2021): 1076–84. https://doi.org/10.1002/ejhf.2196.
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    • Fuery, Michael A., Fouad Chouairi, James L. Januzzi, Gordon W. Moe, Cesar Caraballo, Megan McCullough, P Elliott Miller, et al. “Intercountry Differences in Guideline-Directed Medical Therapy and Outcomes Among Patients With Heart Failure.” Jacc Heart Fail 9, no. 7 (July 2021): 497–505. https://doi.org/10.1016/j.jchf.2021.02.011.
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    • Felker, G Michael, Javed Butler, James L. Januzzi, Akshay S. Desai, John J. V. McMurray, and Scott D. Solomon. “Probabilistic Readjudication of Heart Failure Hospitalization Events in the PARAGON-HF Study.” Circulation 143, no. 23 (June 8, 2021): 2316–18. https://doi.org/10.1161/CIRCULATIONAHA.121.054496.
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    • Murphy, Sean P., Margaret F. Prescott, Alan S. Maisel, Javed Butler, Ileana L. Piña, G Michael Felker, Jonathan H. Ward, et al. “Association Between Angiotensin Receptor-Neprilysin Inhibition, Cardiovascular Biomarkers, and Cardiac Remodeling in Heart Failure With Reduced Ejection Fraction.” Circ Heart Fail 14, no. 6 (June 2021): e008410. https://doi.org/10.1161/CIRCHEARTFAILURE.120.008410.
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    • Perez, Antonio L., Justin L. Grodin, Thanat Chaikijurajai, Yuping Wu, Adrian F. Hernandez, Javed Butler, Marco Metra, et al. “Interleukin-6 and Outcomes in Acute Heart Failure: An ASCEND-HF Substudy.” J Card Fail 27, no. 6 (June 2021): 670–76. https://doi.org/10.1016/j.cardfail.2021.01.006.
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    • Teerlink, John R., G Michael Felker, and John J. V. McMurray. “Omecamtiv Mecarbil in Systolic Heart Failure. Reply.” N Engl J Med 384, no. 20 (May 20, 2021): 1967–68. https://doi.org/10.1056/NEJMc2102893.
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    • Daubert, Melissa A., Eric Yow, Huiman X. Barnhart, Ileana L. Piña, Tariq Ahmad, Eric Leifer, Lawton Cooper, et al. “Differences in NT-proBNP Response and Prognosis in Men and Women With Heart Failure With Reduced Ejection Fraction.” J Am Heart Assoc 10, no. 10 (May 18, 2021): e019712. https://doi.org/10.1161/JAHA.120.019712.
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    • Mann, Douglas L., and G Michael Felker. “Mechanisms and Models in Heart Failure: A Translational Approach.” Circ Res 128, no. 10 (May 14, 2021): 1435–50. https://doi.org/10.1161/CIRCRESAHA.121.318158.
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    • Chouairi, Fouad, Justin Pacor, P Elliott Miller, Michael A. Fuery, Cesar Caraballo, Sounok Sen, Eric S. Leifer, et al. “Effects of Atrial Fibrillation on Heart Failure Outcomes and NT-proBNP Levels in the GUIDE-IT Trial.” Mayo Clin Proc Innov Qual Outcomes 5, no. 2 (April 2021): 447–55. https://doi.org/10.1016/j.mayocpiqo.2021.02.005.
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    • Fudim, Marat, Manesh R. Patel, Richard Boortz-Marx, Barry A. Borlaug, Adam D. DeVore, Arun Ganesh, Cynthia L. Green, et al. “Splanchnic Nerve Block Mediated Changes in Stressed Blood Volume in Heart Failure.” Jacc Heart Fail 9, no. 4 (April 2021): 293–300. https://doi.org/10.1016/j.jchf.2020.12.006.
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    • Ahmad, Tariq, and G Michael Felker. “Setting the Stage for a Multimarker-Based Heart Failure Prevention Trial?” Jacc Heart Fail 9, no. 3 (March 2021): 224–25. https://doi.org/10.1016/j.jchf.2021.01.001.
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    • Bozkurt, Biykem, Andrew J. S. Coats, Hiroyuki Tsutsui, Ca Magdy Abdelhamid, Stamatis Adamopoulos, Nancy Albert, Stefan D. Anker, et al. “Universal definition and classification of heart failure: a report of the Heart Failure Society of America, Heart Failure Association of the European Society of Cardiology, Japanese Heart Failure Society and Writing Committee of the Universal Definition of Heart Failure: Endorsed by the Canadian Heart Failure Society, Heart Failure Association of India, Cardiac Society of Australia and New Zealand, and Chinese Heart Failure Association.” Eur J Heart Fail 23, no. 3 (March 2021): 352–80. https://doi.org/10.1002/ejhf.2115.
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    • Bozkurt, Biykem, Andrew Js Coats, Hiroyuki Tsutsui, Magdy Abdelhamid, Stamatis Adamopoulos, Nancy Albert, Stefan D. Anker, et al. “Universal Definition and Classification of Heart Failure: A Report of the Heart Failure Society of America, Heart Failure Association of the European Society of Cardiology, Japanese Heart Failure Society and Writing Committee of the Universal Definition of Heart Failure.” J Card Fail, March 1, 2021. https://doi.org/10.1016/j.cardfail.2021.01.022.
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    • Greene, Stephen J., Taylor S. Triana, Raluca Ionescu-Ittu, Sherry Shi, Annie Guérin, Mary M. DeSouza, Paul D. Kessler, Aylin Tugcu, Maria Borentain, and G Michael Felker. “Patients Hospitalized for De Novo Versus Worsening Chronic Heart Failure in the United States.” J Am Coll Cardiol 77, no. 7 (February 23, 2021): 1023–25. https://doi.org/10.1016/j.jacc.2020.12.026.
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    • Felker, G Michael, and Stephen J. Greene. “Improving In-Hospital Diuretic Therapy for Heart Failure: The Need for High-Quality Evidence.” J Am Coll Cardiol 77, no. 6 (February 16, 2021): 709–12. https://doi.org/10.1016/j.jacc.2020.12.018.
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    • Felker, G Michael, John J. V. McMurray, John G. Cleland, Christopher M. O’Connor, John R. Teerlink, Adriaan A. Voors, Jan Belohlavek, et al. “Effects of a Novel Nitroxyl Donor in Acute Heart Failure: The STAND-UP AHF Study.” Jacc Heart Fail 9, no. 2 (February 2021): 146–57. https://doi.org/10.1016/j.jchf.2020.10.012.
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    • Fudim, Marat, Nicolas Ashur, Aaron D. Jones, Andrew P. Ambrosy, Bradley A. Bart, Javed Butler, Horng H. Chen, et al. “Implications of peripheral oedema in heart failure with preserved ejection fraction: a heart failure network analysis.” Esc Heart Fail 8, no. 1 (February 2021): 662–69. https://doi.org/10.1002/ehf2.13159.
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    • Khan, Muhammad Shahzeb, G Michael Felker, Ileana L. Piña, Alexander Camacho, Devavrat Bapat, Nasrien E. Ibrahim, Alan S. Maisel, et al. “Reverse Cardiac Remodeling Following Initiation of Sacubitril/Valsartan in Patients With Heart Failure With and Without Diabetes.” Jacc Heart Fail 9, no. 2 (February 2021): 137–45. https://doi.org/10.1016/j.jchf.2020.09.014.
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    • Murphy, Sean P., Margaret F. Prescott, Alexander Camacho, Seethalakshmi R. Iyer, Alan S. Maisel, G Michael Felker, Javed Butler, et al. “Atrial Natriuretic Peptide and Treatment With Sacubitril/Valsartan in Heart Failure With Reduced Ejection Fraction.” Jacc Heart Fail 9, no. 2 (February 2021): 127–36. https://doi.org/10.1016/j.jchf.2020.09.013.
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    • Teerlink, John R., Rafael Diaz, G Michael Felker, John J. V. McMurray, Marco Metra, Scott D. Solomon, Kirkwood F. Adams, et al. “Cardiac Myosin Activation with Omecamtiv Mecarbil in Systolic Heart Failure.” N Engl J Med 384, no. 2 (January 14, 2021): 105–16. https://doi.org/10.1056/NEJMoa2025797.
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    • Bhatt, Ankeet S., William T. Abraham, JoAnn Lindenfeld, Michael Bristow, Peter E. Carson, G Michael Felker, Gregg C. Fonarow, et al. “Treatment of HF in an Era of Multiple Therapies: Statement From the HF Collaboratory.” Jacc Heart Fail 9, no. 1 (January 2021): 1–12. https://doi.org/10.1016/j.jchf.2020.10.014.
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    • Ibrahim, Nasrien E., Ileana L. Piña, Alexander Camacho, Devavrat Bapat, G Michael Felker, Alan S. Maisel, Javed Butler, et al. “Racial and Ethnic Differences in Biomarkers, Health Status, and Cardiac Remodeling in Patients With Heart Failure With Reduced Ejection Fraction Treated With Sacubitril/Valsartan.” Circ Heart Fail 13, no. 11 (November 2020): e007829. https://doi.org/10.1161/CIRCHEARTFAILURE.120.007829.
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    • Psotka, Mitchell A., Mona Fiuzat, Scott D. Solomon, Cynthia Chauhan, G Michael Felker, Javed Butler, John R. Teerlink, Shashank S. Sinha, Christopher M. O’Connor, and Marvin A. Konstam. “Challenges and Potential Improvements to Patient Access to Pharmaceuticals: Examples From Cardiology.” Circulation 142, no. 8 (August 25, 2020): 790–98. https://doi.org/10.1161/CIRCULATIONAHA.119.044976.
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    • Teerlink, John R., Rafael Diaz, G Michael Felker, John J. V. McMurray, Marco Metra, Scott D. Solomon, Jason C. Legg, et al. “Omecamtiv Mecarbil in Chronic Heart Failure With Reduced Ejection Fraction: Rationale and Design of GALACTIC-HF.” Jacc Heart Fail 8, no. 4 (April 2020): 329–40. https://doi.org/10.1016/j.jchf.2019.12.001.
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    • Reddy, Yogesh N. V., Masaru Obokata, Jeffrey M. Testani, G Michael Felker, WH Wilson Tang, Omar F. Abou-Ezzeddine, Jie-Lena Sun, et al. “Adverse Renal Response to Decongestion in the Obese Phenotype of Heart Failure With Preserved Ejection Fraction.” J Card Fail 26, no. 2 (February 2020): 101–7. https://doi.org/10.1016/j.cardfail.2019.09.015.
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    • Sharma, Abhinav, Jingjing Wu, Justin A. Ezekowitz, Gary Michael Felker, Jacob A. Udell, Paul A. Heidenreich, Gregg C. Fonarow, Kenneth W. Mahaffey, Adrian F. Hernandez, and Adam D. DeVore. “Eligibility of sodium-glucose co-transporter-2 inhibitors among patients with diabetes mellitus admitted for heart failure.” Esc Heart Fail 7, no. 1 (February 2020): 274–78. https://doi.org/10.1002/ehf2.12528.
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    • Wohlfahrt, Peter, Susan L. Zickmund, Stacey Slager, Larry A. Allen, Jose Nativi Nicolau, Abdallah G. Kfoury, G Michael Felker, et al. “Provider Perspectives on the Feasibility and Utility of Routine Patient-Reported Outcomes Assessment in Heart Failure: A Qualitative Analysis.” J Am Heart Assoc 9, no. 2 (January 21, 2020): e013047. https://doi.org/10.1161/JAHA.119.013047.
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    • Lyle, Melissa A., Seethalakshmi R. Iyer, Margaret M. Redfield, Yogesh N. V. Reddy, G Michael Felker, Thomas P. Cappola, Adrian F. Hernandez, Christopher G. Scott, John C. Burnett, and Naveen L. Pereira. “Circulating Neprilysin in Patients With Heart Failure and Preserved Ejection Fraction.” Jacc Heart Fail 8, no. 1 (January 2020): 70–80. https://doi.org/10.1016/j.jchf.2019.07.005.
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    • Greene, Stephen J., G Michael Felker, Anna Giczewska, Andreas P. Kalogeropoulos, Andrew P. Ambrosy, Hrishikesh Chakraborty, Adam D. DeVore, et al. “Spironolactone in Acute Heart Failure Patients With Renal Dysfunction and Risk Factors for Diuretic Resistance: From the ATHENA-HF Trial.” Can J Cardiol 35, no. 9 (September 2019): 1097–1105. https://doi.org/10.1016/j.cjca.2019.01.022.
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    • Greene, Stephen J., and G Michael Felker. “The Urgency of Doing: Addressing Gaps in Use of Evidence-Based Medical Therapy for Heart Failure.” Jacc Heart Fail 7, no. 1 (January 2019): 22–24. https://doi.org/10.1016/j.jchf.2018.11.006.
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    • Patel, Ravi B., Muthiah Vaduganathan, Aruna Rikhi, Hrishikesh Chakraborty, Stephen J. Greene, Adrian F. Hernandez, G Michael Felker, Margaret M. Redfield, Javed Butler, and Sanjiv J. Shah. “History of Atrial Fibrillation and Trajectory of Decongestion in Acute Heart Failure.” Jacc Heart Fail 7, no. 1 (January 2019): 47–55. https://doi.org/10.1016/j.jchf.2018.09.008.
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    • Fudim, Marat, Arun Ganesh, Cindy Green, W Schuyler Jones, Michael A. Blazing, Adam D. DeVore, G Michael Felker, et al. “Splanchnic nerve block for decompensated chronic heart failure: splanchnic-HF.” Eur Heart J 39, no. 48 (December 21, 2018): 4255–56. https://doi.org/10.1093/eurheartj/ehy682.
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    • Mark, Daniel B., Patricia A. Cowper, Kevin J. Anstrom, Shubin Sheng, Melanie R. Daniels, J David Knight, Khaula N. Baloch, et al. “Economic and Quality-of-Life Outcomes of Natriuretic Peptide-Guided Therapy for Heart Failure.” J Am Coll Cardiol 72, no. 21 (November 27, 2018): 2551–62. https://doi.org/10.1016/j.jacc.2018.08.2184.
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    • Borlaug, Barry A., Kevin J. Anstrom, Gregory D. Lewis, Sanjiv J. Shah, James A. Levine, Gabe A. Koepp, Michael M. Givertz, et al. “Effect of Inorganic Nitrite vs Placebo on Exercise Capacity Among Patients With Heart Failure With Preserved Ejection Fraction: The INDIE-HFpEF Randomized Clinical Trial.” Jama 320, no. 17 (November 6, 2018): 1764–73. https://doi.org/10.1001/jama.2018.14852.
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    • Ahmad, Tariq, and G Michael Felker. “Combating Acute Heart Failure in the Arena: Lessons From the ROPA-DOP Trial.” Jacc Heart Fail 6, no. 10 (October 2018): 871–73. https://doi.org/10.1016/j.jchf.2018.05.009.
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    • Grodin, Justin L., Javed Butler, Marco Metra, G Michael Felker, Adriaan A. Voors, John J. McMurray, Paul W. Armstrong, et al. “Circulating Cardiac Troponin I Levels Measured by a Novel Highly Sensitive Assay in Acute Decompensated Heart Failure: Insights From the ASCEND-HF Trial.” J Card Fail 24, no. 8 (August 2018): 512–19. https://doi.org/10.1016/j.cardfail.2018.06.008.
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    • Parikh, Kishan S., Kavita Sharma, Mona Fiuzat, Howard K. Surks, Jyothis T. George, Narimon Honarpour, Christopher Depre, et al. “Heart Failure With Preserved Ejection Fraction Expert Panel Report: Current Controversies and Implications for Clinical Trials.” Jacc Heart Fail 6, no. 8 (August 2018): 619–32. https://doi.org/10.1016/j.jchf.2018.06.008.
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    • Parikh, Kishan S., Mona Fiuzat, Gordon Davis, Megan Neely, Penny Blain-Nelson, David J. Whellan, William T. Abraham, et al. “Dose Response of β-Blockers in Adrenergic Receptor Polymorphism Genotypes.” Circ Genom Precis Med 11, no. 8 (August 2018): e002210. https://doi.org/10.1161/CIRCGEN.117.002210.
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    • Felker, G Michael, and Marat Fudim. “Unraveling the Mystery of Troponin Elevation in Heart Failure.” J Am Coll Cardiol 71, no. 25 (June 26, 2018): 2917–18. https://doi.org/10.1016/j.jacc.2018.03.537.
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    • Sharma, Abhinav, Sana M. Al-Khatib, Justin A. Ezekowitz, Lauren B. Cooper, Christopher B. Fordyce, G. Michael Felker, Gust H. Bardy, et al. “Implantable cardioverter-defibrillators in heart failure patients with reduced ejection fraction and diabetes.” Eur J Heart Fail 20, no. 6 (June 2018): 1031–38. https://doi.org/10.1002/ejhf.1192.
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    • Sharma, Abhinav, Xin Zhao, Bradley G. Hammill, Adrian F. Hernandez, Gregg C. Fonarow, G Michael Felker, Clyde W. Yancy, Paul A. Heidenreich, Justin A. Ezekowitz, and Adam D. DeVore. “Trends in Noncardiovascular Comorbidities Among Patients Hospitalized for Heart Failure: Insights From the Get With The Guidelines-Heart Failure Registry.” Circ Heart Fail 11, no. 6 (June 2018): e004646. https://doi.org/10.1161/CIRCHEARTFAILURE.117.004646.
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    • Ahmad, Tariq, Keyanna Jackson, Veena S. Rao, WH Wilson Tang, Meredith A. Brisco-Bacik, Horng H. Chen, G Michael Felker, et al. “Worsening Renal Function in Patients With Acute Heart Failure Undergoing Aggressive Diuresis Is Not Associated With Tubular Injury.” Circulation 137, no. 19 (May 8, 2018): 2016–28. https://doi.org/10.1161/CIRCULATIONAHA.117.030112.
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    • Ahmad, Tariq, Lars H. Lund, Pooja Rao, Rohit Ghosh, Prashant Warier, Benjamin Vaccaro, Ulf Dahlström, Christopher M. O’Connor, G Michael Felker, and Nihar R. Desai. “Machine Learning Methods Improve Prognostication, Identify Clinically Distinct Phenotypes, and Detect Heterogeneity in Response to Therapy in a Large Cohort of Heart Failure Patients.” J Am Heart Assoc 7, no. 8 (April 12, 2018). https://doi.org/10.1161/JAHA.117.008081.
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    • Felker, G Michael, and James L. Januzzi. “"Time Is Muscle" in Acute Heart Failure: Critical Concept or Fake News?” Jacc Heart Fail 6, no. 4 (April 2018): 295–97. https://doi.org/10.1016/j.jchf.2018.01.011.
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    • Greene, Stephen J., Robert J. Mentz, and G Michael Felker. “Outpatient Worsening Heart Failure as a Target for Therapy: A Review.” Jama Cardiol 3, no. 3 (March 1, 2018): 252–59. https://doi.org/10.1001/jamacardio.2017.5250.
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    • Ellison, David H., and G Michael Felker. “Diuretic Treatment in Heart Failure.” N Engl J Med 378, no. 7 (February 15, 2018): 684–85. https://doi.org/10.1056/NEJMc1716477.
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    • Metra, Marco, Beth A. Davison, Claudio Gimpelewicz, Valentina Carubelli, G Michael Felker, Gerasimos Filippatos, Barry H. Greenberg, et al. “Site enrollment rate, outcomes, and study drug effects in a multicenter trial. Results from RELAX-AHF.” Int J Cardiol 253 (February 15, 2018): 91–96. https://doi.org/10.1016/j.ijcard.2017.09.185.
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    • Bhatt, Ankeet S., Lauren B. Cooper, Andrew P. Ambrosy, Robert M. Clare, Adrian Coles, Emer Joyce, Arun Krishnamoorthy, et al. “Interaction of Body Mass Index on the Association Between N-Terminal-Pro-b-Type Natriuretic Peptide and Morbidity and Mortality in Patients With Acute Heart Failure: Findings From ASCEND-HF (Acute Study of Clinical Effectiveness of Nesiritide in Decompensated Heart Failure).” J Am Heart Assoc 7, no. 3 (February 3, 2018). https://doi.org/10.1161/JAHA.117.006740.
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    • Cotter, Gad, Beth A. Davison, Javed Butler, Sean P. Collins, Justin A. Ezekowitz, G Michael Felker, Gerasimos Filippatos, et al. “Relationship between baseline systolic blood pressure and long-term outcomes in acute heart failure patients treated with TRV027: an exploratory subgroup analysis of BLAST-AHF.” Clin Res Cardiol 107, no. 2 (February 2018): 170–81. https://doi.org/10.1007/s00392-017-1168-0.
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    • Greene, Stephen J., and G Michael Felker. “Considering the duration of heart failure: using the past to predict the future.” Eur J Heart Fail 20, no. 2 (February 2018): 382–84. https://doi.org/10.1002/ejhf.1064.
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    • Fudim, Marat, Christopher M. O’Connor, Allison Dunning, Andrew P. Ambrosy, Paul W. Armstrong, Adrian Coles, Justin A. Ezekowitz, et al. “Aetiology, timing and clinical predictors of early vs. late readmission following index hospitalization for acute heart failure: insights from ASCEND-HF.” Eur J Heart Fail 20, no. 2 (February 2018): 304–14. https://doi.org/10.1002/ejhf.1020.
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    • Greene, Stephen J., and G Michael Felker. “Innovation in Diuretic Therapy: The Missing Ingredient for Treating Worsening Heart Failure Outside the Hospital?” Jacc Basic Transl Sci 3, no. 1 (February 2018): 35–37. https://doi.org/10.1016/j.jacbts.2018.01.002.
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    • McTiernan, Charles F., Penelope Morel, Leslie T. Cooper, Navin Rajagopalan, Vinay Thohan, Mark Zucker, John Boehmer, et al. “Circulating T-Cell Subsets, Monocytes, and Natural Killer Cells in Peripartum Cardiomyopathy: Results From the Multicenter IPAC Study.” J Card Fail 24, no. 1 (January 2018): 33–42. https://doi.org/10.1016/j.cardfail.2017.10.012.
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    • Collins, Sean P., Phillip D. Levy, Gregory J. Fermann, Michael M. Givertz, Jennifer M. Martindale, Peter S. Pang, Alan B. Storrow, et al. “What's Next for Acute Heart Failure Research?” Acad Emerg Med 25, no. 1 (January 2018): 85–93. https://doi.org/10.1111/acem.13331.
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    • Ellison, David H., and G Michael Felker. “Diuretic Treatment in Heart Failure.” N Engl J Med 377, no. 20 (November 16, 2017): 1964–75. https://doi.org/10.1056/NEJMra1703100.
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    • Filippatos, Gerasimos, Dimitrios Farmakis, Marco Metra, Gad Cotter, Beth A. Davison, G Michael Felker, Barry H. Greenberg, et al. “Erratum to: Serelaxin in acute heart failure patients with and without atrial fibrillation: a secondary analysis of the RELAX-AHF trial.” Clin Res Cardiol 106, no. 11 (November 2017): 938. https://doi.org/10.1007/s00392-017-1139-5.
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    • Sharma, Abhinav, Susanna R. Stevens, Joseph Lucas, Mona Fiuzat, Kirkwood F. Adams, David J. Whellan, Mark P. Donahue, et al. “Utility of Growth Differentiation Factor-15, A Marker of Oxidative Stress and Inflammation, in Chronic Heart Failure: Insights From the HF-ACTION Study.” Jacc Heart Fail 5, no. 10 (October 2017): 724–34. https://doi.org/10.1016/j.jchf.2017.07.013.
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    • Butler, Javed, Kevin J. Anstrom, G Michael Felker, Michael M. Givertz, Andreas P. Kalogeropoulos, Marvin A. Konstam, Douglas L. Mann, et al. “Efficacy and Safety of Spironolactone in Acute Heart Failure: The ATHENA-HF Randomized Clinical Trial.” Jama Cardiol 2, no. 9 (September 1, 2017): 950–58. https://doi.org/10.1001/jamacardio.2017.2198.
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    • Felker, G Michael, Kevin J. Anstrom, Kirkwood F. Adams, Justin A. Ezekowitz, Mona Fiuzat, Nancy Houston-Miller, James L. Januzzi, et al. “Effect of Natriuretic Peptide-Guided Therapy on Hospitalization or Cardiovascular Mortality in High-Risk Patients With Heart Failure and Reduced Ejection Fraction: A Randomized Clinical Trial.” Jama 318, no. 8 (August 22, 2017): 713–20. https://doi.org/10.1001/jama.2017.10565.
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    • Fudim, Marat, Adrian F. Hernandez, and G Michael Felker. “Role of Volume Redistribution in the Congestion of Heart Failure.” J Am Heart Assoc 6, no. 8 (August 17, 2017). https://doi.org/10.1161/JAHA.117.006817.
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    • Pang, Peter S., Javed Butler, Sean P. Collins, Gad Cotter, Beth A. Davison, Justin A. Ezekowitz, Gerasimos Filippatos, et al. “Biased ligand of the angiotensin II type 1 receptor in patients with acute heart failure: a randomized, double-blind, placebo-controlled, phase IIB, dose ranging trial (BLAST-AHF).” Eur Heart J 38, no. 30 (August 7, 2017): 2364–73. https://doi.org/10.1093/eurheartj/ehx196.
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    • Demissei, Biniyam G., Gad Cotter, Margaret F. Prescott, G Michael Felker, Gerasimos Filippatos, Barry H. Greenberg, Peter S. Pang, et al. “A multimarker multi-time point-based risk stratification strategy in acute heart failure: results from the RELAX-AHF trial.” Eur J Heart Fail 19, no. 8 (August 2017): 1001–10. https://doi.org/10.1002/ejhf.749.
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    • Gimpelewicz, Claudio, Marco Metra, John G. F. Cleland, Peter Szecsödy, Chuan-Chuan Chang Wun, Leandro Boer-Martins, Gad Cotter, et al. “Effects of serelaxin on the outcome of patients with or without substantial peripheral edema: A subgroup analysis from the RELAX-AHF trial.” Am Heart J 190 (August 2017): 113–22. https://doi.org/10.1016/j.ahj.2017.05.012.
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    • Wang, Hanghang, Kevin Anstrom, Olga Ilkayeva, Michael J. Muehlbauer, James R. Bain, Steven McNulty, Christopher B. Newgard, et al. “Sildenafil Treatment in Heart Failure With Preserved Ejection Fraction: Targeted Metabolomic Profiling in the RELAX Trial.” Jama Cardiol 2, no. 8 (August 1, 2017): 896–901. https://doi.org/10.1001/jamacardio.2017.1239.
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    • Ambrosy, Andrew P., Ankeet S. Bhatt, Dianne Gallup, Kevin J. Anstrom, Javed Butler, Adam D. DeVore, G Michael Felker, et al. “Trajectory of Congestion Metrics by Ejection Fraction in Patients With Acute Heart Failure (from the Heart Failure Network).” Am J Cardiol 120, no. 1 (July 1, 2017): 98–105. https://doi.org/10.1016/j.amjcard.2017.03.249.
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    • Januzzi, James L., and G Michael Felker. “Door-to-Furosemide Therapy in the ED: New Quality Metric or Just a Piece of the Puzzle?” J Am Coll Cardiol 69, no. 25 (June 27, 2017): 3052–54. https://doi.org/10.1016/j.jacc.2017.05.009.
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    • Grodin, Justin L., Dianne Gallup, Kevin J. Anstrom, G Michael Felker, Horng H. Chen, and WH Wilson Tang. “Implications of Alternative Hepatorenal Prognostic Scoring Systems in Acute Heart Failure (from DOSE-AHF and ROSE-AHF).” Am J Cardiol 119, no. 12 (June 15, 2017): 2003–9. https://doi.org/10.1016/j.amjcard.2017.03.031.
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    • Banks, Adam, Samuel Broderick, Karen Chiswell, Linda Shaw, Adam Devore, Mona Fiuzat, Christopher O’Connor, Gary Michael Felker, Eric Velazquez, and Robert Mentz. “Comparison of Clinical Characteristics and Outcomes of Patients With Versus Without Diabetes Mellitus and With Versus Without Angina Pectoris (from the Duke Databank for Cardiovascular Disease).” Am J Cardiol 119, no. 11 (June 1, 2017): 1703–9. https://doi.org/10.1016/j.amjcard.2017.02.053.
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    • Filippatos, Gerasimos, Dimitrios Farmakis, Marco Metra, Gad Cotter, Beth A. Davison, G Michael Felker, Barry H. Greenberg, et al. “Serelaxin in acute heart failure patients with and without atrial fibrillation: a secondary analysis of the RELAX-AHF trial.” Clin Res Cardiol 106, no. 6 (June 2017): 444–56. https://doi.org/10.1007/s00392-016-1074-x.
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    • Teerlink, John R., Adriaan A. Voors, Piotr Ponikowski, Peter S. Pang, Barry H. Greenberg, Gerasimos Filippatos, G Michael Felker, et al. “Serelaxin in addition to standard therapy in acute heart failure: rationale and design of the RELAX-AHF-2 study.” Eur J Heart Fail 19, no. 6 (June 2017): 800–809. https://doi.org/10.1002/ejhf.830.
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    • Chow, Sheryl L., Alan S. Maisel, Inder Anand, Biykem Bozkurt, Rudolf A. de Boer, G Michael Felker, Gregg C. Fonarow, et al. “Role of Biomarkers for the Prevention, Assessment, and Management of Heart Failure: A Scientific Statement From the American Heart Association.” Circulation 135, no. 22 (May 30, 2017): e1054–91. https://doi.org/10.1161/CIR.0000000000000490.
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    • Lewis, Gregory D., Rajeev Malhotra, Adrian F. Hernandez, Steven E. McNulty, Andrew Smith, G Michael Felker, WH Wilson Tang, et al. “Effect of Oral Iron Repletion on Exercise Capacity in Patients With Heart Failure With Reduced Ejection Fraction and Iron Deficiency: The IRONOUT HF Randomized Clinical Trial.” Jama 317, no. 19 (May 16, 2017): 1958–66. https://doi.org/10.1001/jama.2017.5427.
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    • Bloomfield, Gerald S., and G Michael Felker. “Heart Failure With Reduced Ejection Fraction in Human Immunodeficiency Virus Infection: The More Things Stay the Same.” Jama Cardiol 2, no. 5 (May 1, 2017): 476–77. https://doi.org/10.1001/jamacardio.2017.0282.
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    • Pang, Peter S., John R. Teerlink, Leandro Boer-Martins, Claudio Gimpelewicz, Beth A. Davison, Yi Wang, Adriaan A. Voors, et al. “Day vs night: Does time of presentation matter in acute heart failure? A secondary analysis from the RELAX-AHF trial.” Am Heart J 187 (May 2017): 62–69. https://doi.org/10.1016/j.ahj.2017.02.024.
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    • Schelbert, Erik B., Uri Elkayam, Leslie T. Cooper, Michael M. Givertz, Jeffrey D. Alexis, Joan Briller, G Michael Felker, et al. “Myocardial Damage Detected by Late Gadolinium Enhancement Cardiac Magnetic Resonance Is Uncommon in Peripartum Cardiomyopathy.” J Am Heart Assoc 6, no. 4 (April 3, 2017). https://doi.org/10.1161/JAHA.117.005472.
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    • Meyer, Sven, John R. Teerlink, Marco Metra, Piotr Ponikowski, Gad Cotter, Beth A. Davison, G Michael Felker, et al. “Sex differences in early dyspnea relief between men and women hospitalized for acute heart failure: insights from the RELAX-AHF study.” Clin Res Cardiol 106, no. 4 (April 2017): 280–92. https://doi.org/10.1007/s00392-016-1051-4.
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    • Parikh, Kishan S., Youlan Rao, Tariq Ahmad, Kai Shen, G Michael Felker, and Sudarshan Rajagopal. “Novel approach to classifying patients with pulmonary arterial hypertension using cluster analysis.” Pulm Circ 7, no. 2 (April 2017): 486–93. https://doi.org/10.1177/2045893217705891.
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    • Felker, G Michael, Robert J. Mentz, Robert T. Cole, Kirkwood F. Adams, Gregory F. Egnaczyk, Mona Fiuzat, Chetan B. Patel, et al. “Efficacy and Safety of Tolvaptan in Patients Hospitalized With Acute Heart Failure.” J Am Coll Cardiol 69, no. 11 (March 21, 2017): 1399–1406. https://doi.org/10.1016/j.jacc.2016.09.004.
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    • AbouEzzeddine, Omar F., Paul M. McKie, Shannon M. Dunlay, Susanna R. Stevens, G Michael Felker, Barry A. Borlaug, Horng H. Chen, Russell P. Tracy, Eugene Braunwald, and Margaret M. Redfield. “Suppression of Tumorigenicity 2 in Heart Failure With Preserved Ejection Fraction.” J Am Heart Assoc 6, no. 2 (February 18, 2017). https://doi.org/10.1161/JAHA.116.004382.
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    • Felker, G Michael, and David J. Whellan. “Inpatient Management of Heart Failure: Are We Shooting at the Right Target?” Ann Intern Med 166, no. 3 (February 7, 2017): 223–24. https://doi.org/10.7326/M16-2667.
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    • Ambrosy, Andrew P., Lukasz P. Cerbin, Paul W. Armstrong, Laved Butler, Adrian Coles, Adam D. DeVore, Mark E. Dunlap, et al. “Body Weight Change During and After Hospitalization for Acute Heart Failure: Patient Characteristics, Markers of Congestion, and Outcomes Findings From the ASCEND-HF Trial.” Jacc Heart Failure 5, no. 1 (January 1, 2017): 3–13.
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    • Ambrosy, Andrew P., Lukasz P. Cerbin, Paul W. Armstrong, Javed Butler, Adrian Coles, Adam D. DeVore, Mark E. Dunlap, et al. “Body Weight Change During and After Hospitalization for Acute Heart Failure: Patient Characteristics, Markers of Congestion, and Outcomes: Findings From the ASCEND-HF Trial.” Jacc Heart Fail 5, no. 1 (January 2017): 1–13. https://doi.org/10.1016/j.jchf.2016.09.012.
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    • Apple, Fred S., Louise Cullen, G Michael Felker, Geoffrey Ginsburg, and David Morrow. “Cardiovascular Disease: Impact of Biomarkers, Proteomics, and Genomics.” Clin Chem 63, no. 1 (January 2017): 1–4. https://doi.org/10.1373/clinchem.2016.263350.
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    • Teerlink, John R., G Michael Felker, John J. V. McMurray, Scott D. Solomon, Kirkwood F. Adams, John G. F. Cleland, Justin A. Ezekowitz, et al. “Chronic Oral Study of Myosin Activation to Increase Contractility in Heart Failure (COSMIC-HF): a phase 2, pharmacokinetic, randomised, placebo-controlled trial.” Lancet 388, no. 10062 (December 10, 2016): 2895–2903. https://doi.org/10.1016/S0140-6736(16)32049-9.
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    • Brown, Paul M., Kevin J. Anstrom, G Michael Felker, and Justin A. Ezekowitz. “Composite End Points in Acute Heart Failure Research: Data Simulations Illustrate the Limitations.” Can J Cardiol 32, no. 11 (November 2016): 1356.e21-1356.e28. https://doi.org/10.1016/j.cjca.2016.02.067.
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    • AbouEzzeddine, Omar F., Paul M. McKie, Christopher G. Scott, Richard J. Rodeheffer, Horng H. Chen, G. Michael Felker, Allan S. Jaffe, John C. Burnett, and Margaret M. Redfield. “Biomarker-based risk prediction in the community.” Eur J Heart Fail 18, no. 11 (November 2016): 1342–50. https://doi.org/10.1002/ejhf.663.
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    • Butler, Javed, Adrian F. Hernandez, Kevin J. Anstrom, Andreas Kalogeropoulos, Margaret M. Redfield, Marvin A. Konstam, WH Wilson Tang, G Michael Felker, Monica R. Shah, and Eugene Braunwald. “Rationale and Design of the ATHENA-HF Trial: Aldosterone Targeted Neurohormonal Combined With Natriuresis Therapy in Heart Failure.” Jacc Heart Fail 4, no. 9 (September 2016): 726–35. https://doi.org/10.1016/j.jchf.2016.06.003.
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    • Krishnamurthy, Yamini, Lauren B. Cooper, Kishan S. Parikh, G Michael Felker, Carmelo A. Milano, Joseph G. Rogers, Adrian F. Hernandez, and Chetan B. Patel. “Pulmonary Hypertension in the Era of Mechanical Circulatory Support.” Asaio J 62, no. 5 (September 2016): 505–12. https://doi.org/10.1097/MAT.0000000000000408.
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    • Cooper, Lauren B., Robert J. Mentz, Dianne Gallup, Anuradha Lala, Adam D. DeVore, Justin M. Vader, Omar F. AbouEzzeddine, et al. “Serum Bicarbonate in Acute Heart Failure: Relationship to Treatment Strategies and Clinical Outcomes.” J Card Fail 22, no. 9 (September 2016): 738–42. https://doi.org/10.1016/j.cardfail.2016.01.007.
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    • Liu, Licette C. Y., Adriaan A. Voors, John R. Teerlink, Gad Cotter, Beth A. Davison, G Michael Felker, Gerasimos Filippatos, et al. “Effects of serelaxin in acute heart failure patients with renal impairment: results from RELAX-AHF.” Clin Res Cardiol 105, no. 9 (September 2016): 727–37. https://doi.org/10.1007/s00392-016-0979-8.
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    • Kelly, Jacob P., Bradley G. Hammill, Jacob A. Doll, G Michael Felker, Paul A. Heidenreich, Deepak L. Bhatt, Clyde W. Yancy, Gregg C. Fonarow, and Adrian F. Hernandez. “The Potential Impact of Expanding Cardiac Rehabilitation in Heart Failure.” J Am Coll Cardiol 68, no. 9 (August 30, 2016): 977–78. https://doi.org/10.1016/j.jacc.2016.05.081.
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    • Margulies, Kenneth B., Adrian F. Hernandez, Margaret M. Redfield, Michael M. Givertz, Guilherme H. Oliveira, Robert Cole, Douglas L. Mann, et al. “Effects of Liraglutide on Clinical Stability Among Patients With Advanced Heart Failure and Reduced Ejection Fraction: A Randomized Clinical Trial.” Jama 316, no. 5 (August 2, 2016): 500–508. https://doi.org/10.1001/jama.2016.10260.
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    • Collins, Sean P., Phillip D. Levy, Jennifer L. Martindale, Mark E. Dunlap, Alan B. Storrow, Peter S. Pang, Nancy M. Albert, et al. “Clinical and Research Considerations for Patients With Hypertensive Acute Heart Failure: A Consensus Statement from the Society of Academic Emergency Medicine and the Heart Failure Society of America Acute Heart Failure Working Group.” J Card Fail 22, no. 8 (August 2016): 618–27. https://doi.org/10.1016/j.cardfail.2016.04.015.
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    • Ahmad, Tariq, and G Michael Felker. “Reply: applying cluster analysis to data of previously published chronic heart failure trials: systems biology and clinical phenotypes of heart failure syndrome.” J Am Coll Cardiol 65, no. 12 (March 31, 2015): 1270–71. https://doi.org/10.1016/j.jacc.2014.12.050.
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    • Greenberg, Barry, Alex Yaroshinsky, Krisztina M. Zsebo, Javed Butler, G Michael Felker, Adriaan A. Voors, Jeffrey J. Rudy, Kim Wagner, and Roger J. Hajjar. “Design of a phase 2b trial of intracoronary administration of AAV1/SERCA2a in patients with advanced heart failure: the CUPID 2 trial (calcium up-regulation by percutaneous administration of gene therapy in cardiac disease phase 2b).” Jacc Heart Fail 2, no. 1 (February 2014): 84–92. https://doi.org/10.1016/j.jchf.2013.09.008.
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    • Fiuzat, Mona, Phillip J. Schulte, Michael Felker, Tariq Ahmad, Megan Neely, Kirkwood F. Adams, Mark P. Donahue, et al. “Relationship between galectin-3 levels and mineralocorticoid receptor antagonist use in heart failure: analysis from HF-ACTION.” J Card Fail 20, no. 1 (January 2014): 38–44. https://doi.org/10.1016/j.cardfail.2013.11.011.
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    • Wang, Teresa S., Adrian F. Hernandez, G Michael Felker, Carmelo A. Milano, Joseph G. Rogers, and Chetan B. Patel. “Valvular heart disease in patients supported with left ventricular assist devices.” Circ Heart Fail 7, no. 1 (January 2014): 215–22. https://doi.org/10.1161/CIRCHEARTFAILURE.113.000473.
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    • Chen, Horng H., Barry A. Borlaug, Kevin J. Anstrom, G. M. Felker, Michael M. Givertz, Anita Deswal, Bradley A. Bart, et al. “Renal Optimization Strategies Evaluation in Acute Heart Failure (ROSE AHF) Trial.” Circulation 128, no. 24 (December 17, 2013): 2707–8.
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    • Felker, G Michael, Mona Fiuzat, Vivian Thompson, Linda K. Shaw, Megan L. Neely, Kirkwood F. Adams, David J. Whellan, et al. “Soluble ST2 in ambulatory patients with heart failure: Association with functional capacity and long-term outcomes.” Circ Heart Fail 6, no. 6 (November 2013): 1172–79. https://doi.org/10.1161/CIRCHEARTFAILURE.113.000207.
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    • Samsky, Marc D., Chetan B. Patel, Ashleigh Owen, Phillip J. Schulte, Jacob Jentzer, Paul B. Rosenberg, G Michael Felker, Carmelo A. Milano, Adrian F. Hernandez, and Joseph G. Rogers. “Ten-year experience with extended criteria cardiac transplantation.” Circ Heart Fail 6, no. 6 (November 2013): 1230–38. https://doi.org/10.1161/CIRCHEARTFAILURE.113.000296.
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    • Felker, G Michael, and Tariq Ahmad. “Natriuretic peptides and primary prevention: the new world?” J Am Coll Cardiol 62, no. 15 (October 8, 2013): 1373–75. https://doi.org/10.1016/j.jacc.2013.06.009.
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    • Metra, Marco, Piotr Ponikowski, Gad Cotter, Beth A. Davison, G Michael Felker, Gerasimos Filippatos, Barry H. Greenberg, et al. “Effects of serelaxin in subgroups of patients with acute heart failure: results from RELAX-AHF.” Eur Heart J 34, no. 40 (October 2013): 3128–36. https://doi.org/10.1093/eurheartj/eht371.
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    • Mentz, Robert J., Gary Michael Felker, Tariq Ahmad, William Frank Peacock, Bertram Pitt, Mona Fiuzat, Aldo P. Maggioni, et al. “Learning from recent trials and shaping the future of acute heart failure trials.” Am Heart J 166, no. 4 (October 2013): 629–35. https://doi.org/10.1016/j.ahj.2013.08.001.
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    • Schmieder, Roland E. “RELAX-AHF: consistency across subgroups and new hypotheses generated.” Eur Heart J 34, no. 40 (October 2013): 3100–3101. https://doi.org/10.1093/eurheartj/eht380.
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    • Chen, Horng H., Omar F. AbouEzzeddine, Kevin J. Anstrom, Michael M. Givertz, Bradley A. Bart, G Michael Felker, Adrian F. Hernandez, et al. “Targeting the kidney in acute heart failure: can old drugs provide new benefit? Renal Optimization Strategies Evaluation in Acute Heart Failure (ROSE AHF) trial.” Circ Heart Fail 6, no. 5 (September 1, 2013): 1087–94. https://doi.org/10.1161/CIRCHEARTFAILURE.113.000347.
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    • Fiuzat, Mona, Christopher M. O’Connor, Francois Gueyffier, Alice M. Mascette, Nancy L. Geller, Alexandre Mebazaa, Adriaan A. Voors, et al. “Biomarker-guided therapies in heart failure: a forum for unified strategies.” J Card Fail 19, no. 8 (August 2013): 592–99. https://doi.org/10.1016/j.cardfail.2013.05.012.
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    • Mentz, Robert J., Valentina Lazzarini, Mona Fiuzat, Marco Metra, Christopher M. O’Connor, and G Michael Felker. “Is there a rationale for antiplatelet therapy in acute heart failure?” Circ Heart Fail 6, no. 4 (July 2013): 869–76. https://doi.org/10.1161/CIRCHEARTFAILURE.112.000381.
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    • Mentz, Robert J., and G Michael Felker. “Noncardiac comorbidities and acute heart failure patients.” Heart Fail Clin 9, no. 3 (July 2013): 359–vii. https://doi.org/10.1016/j.hfc.2013.04.003.
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    • Samsky, Marc D., Chetan B. Patel, Tracy A. DeWald, Alastair D. Smith, G Michael Felker, Joseph G. Rogers, and Adrian F. Hernandez. “Cardiohepatic interactions in heart failure: an overview and clinical implications.” J Am Coll Cardiol 61, no. 24 (June 18, 2013): 2397–2405. https://doi.org/10.1016/j.jacc.2013.03.042.
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    • Januzzi, James L., and G Michael Felker. “Surfing the biomarker tsunami at JACC: heart failure.” Jacc Heart Fail 1, no. 3 (June 2013): 213–15. https://doi.org/10.1016/j.jchf.2013.03.007.
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    • Patel, Manesh R., Richard D. White, Suhny Abbara, David A. Bluemke, Robert J. Herfkens, Michael Picard, Leslee J. Shaw, et al. “2013 ACCF/ACR/ASE/ASNC/SCCT/SCMR appropriate utilization of cardiovascular imaging in heart failure: a joint report of the American College of Radiology Appropriateness Criteria Committee and the American College of Cardiology Foundation Appropriate Use Criteria Task Force.” J Am Coll Cardiol 61, no. 21 (May 28, 2013): 2207–31. https://doi.org/10.1016/j.jacc.2013.02.005.
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    • Fiuzat, M., G. M. Felker, P. Shulte, M. Neely, K. Adams, M. Donahue, W. Kraus, I. Pina, D. Whellan, and C. M. O’connor. “Relationship between Galectin-3 Levels and Aldosterone Antagonist Use in Heart Failure: Analysis from the HF-ACTION Study.” European Journal of Heart Failure 12 (May 1, 2013): S273–S273.
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    • Metra, M., J. R. Teerlink, G. Cotter, B. A. Davison, G. M. Felker, G. Filippatos, B. H. Greenberg, P. Ponikowski, A. A. Voors, and T. Severin. “Effects of serelaxin on blood pressure: results from the RELAX-AHF Trial.” European Journal of Heart Failure 12 (May 1, 2013): S9–10.
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    • Teerlink, J. R., G. M. Felker, J. J. V. Mc Murray, J. B. Kim, B. Knusel, L. Lei, F. I. Malik, and S. M. Wasserman. “The rationale and design of the Acute Treatment with Omecamtiv Mecarbil to Increase Contractility in Acute Heart Failure (ATOMIC-AHF) study: a phase 2, cohort study of a novel cardiac myosin activator.” European Journal of Heart Failure 12 (May 1, 2013): S308–9.
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    • Teerlink, J. R., M. Metra, G. Cotter, B. A. Davison, G. M. Felker, G. M. Filippatos, B. H. Greenberg, P. Ponikowski, A. A. Voors, and E. Unemori. “Dyspnea relief with serelaxin-treatment in patients with acute heart failure in the RELAX-AHF trial: the earlier the better?” European Journal of Heart Failure 12 (May 1, 2013): S25–S25.
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    • Mentz, Robert J., Kelly Schlendorf, Adrian F. Hernandez, Carmelo A. Milano, G Michael Felker, Laura J. Blue, Jacob N. Schroder, Joseph G. Rogers, and Chetan B. Patel. “Dysphagia in the setting of left ventricular assist device hemolysis.” Asaio J 59, no. 3 (May 2013): 322–23. https://doi.org/10.1097/MAT.0b013e31828bbb00.
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    • Mentz, Robert J., Adrian F. Hernandez, Amanda Stebbins, Justin A. Ezekowitz, G Michael Felker, Gretchen M. Heizer, Dan Atar, et al. “Predictors of early dyspnoea relief in acute heart failure and the association with 30-day outcomes: findings from ASCEND-HF.” Eur J Heart Fail 15, no. 4 (April 2013): 456–64. https://doi.org/10.1093/eurjhf/hfs188.
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    • Redfield, Margaret M., Horng H. Chen, Barry A. Borlaug, Marc J. Semigran, Kerry L. Lee, Gregory Lewis, Martin M. LeWinter, et al. “Effect of phosphodiesterase-5 inhibition on exercise capacity and clinical status in heart failure with preserved ejection fraction: a randomized clinical trial.” Jama 309, no. 12 (March 27, 2013): 1268–77. https://doi.org/10.1001/jama.2013.2024.
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    • Fiuzat, Mona, Megan L. Neely, Aijing Z. Starr, William E. Kraus, G Michael Felker, Mark Donahue, Kirkwood Adams, Ileana L. Piña, David Whellan, and Christopher M. O’Connor. “Association between adrenergic receptor genotypes and beta-blocker dose in heart failure patients: analysis from the HF-ACTION DNA substudy.” Eur J Heart Fail 15, no. 3 (March 2013): 258–66. https://doi.org/10.1093/eurjhf/hfs175.
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    • Kociol, Robb D., Steven E. McNulty, Adrian F. Hernandez, Kerry L. Lee, Margaret M. Redfield, Russell P. Tracy, Eugene Braunwald, Christopher M. O’Connor, G Michael Felker, and G Michael NHLBI Heart Failure Network Steering Committee and Investigators. “Markers of decongestion, dyspnea relief, and clinical outcomes among patients hospitalized with acute heart failure.” Circ Heart Fail 6, no. 2 (March 2013): 240–45. https://doi.org/10.1161/CIRCHEARTFAILURE.112.969246.
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    • Martin, Seth S., Fang-Shu Ou, L Kristin Newby, Victoria Sutton, Patricia Adams, G Michael Felker, and Tracy Y. Wang. “Patient- and trial-specific barriers to participation in cardiovascular randomized clinical trials.” J Am Coll Cardiol 61, no. 7 (February 19, 2013): 762–69. https://doi.org/10.1016/j.jacc.2012.10.046.
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    • Muñoz, Daniel, and G Michael Felker. “Approaches to decongestion in patients with acute decompensated heart failure.” Curr Cardiol Rep 15, no. 2 (February 2013): 335. https://doi.org/10.1007/s11886-012-0335-1.
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    • Metra, Marco, Gad Cotter, Beth A. Davison, G Michael Felker, Gerasimos Filippatos, Barry H. Greenberg, Piotr Ponikowski, et al. “Effect of serelaxin on cardiac, renal, and hepatic biomarkers in the Relaxin in Acute Heart Failure (RELAX-AHF) development program: correlation with outcomes.” J Am Coll Cardiol 61, no. 2 (January 15, 2013): 196–206. https://doi.org/10.1016/j.jacc.2012.11.005.
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    • Teerlink, John R., Gad Cotter, Beth A. Davison, G Michael Felker, Gerasimos Filippatos, Barry H. Greenberg, Piotr Ponikowski, et al. “Serelaxin, recombinant human relaxin-2, for treatment of acute heart failure (RELAX-AHF): a randomised, placebo-controlled trial.” Lancet 381, no. 9860 (January 5, 2013): 29–39. https://doi.org/10.1016/S0140-6736(12)61855-8.
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    • Felker, G. M. “Acute Decompensated Heart Failure,” January 1, 2013, 166–71. https://doi.org/10.1016/B978-1-4557-4815-0.00022-2.
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    • Bart, Bradley A., Steven R. Goldsmith, Kerry L. Lee, Michael M. Givertz, Christopher M. O’Connor, David A. Bull, Margaret M. Redfield, et al. “Ultrafiltration in decompensated heart failure with cardiorenal syndrome.” N Engl J Med 367, no. 24 (December 13, 2012): 2296–2304. https://doi.org/10.1056/NEJMoa1210357.
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    • Ahmad, Tariq, and G Michael Felker. “Subcutaneous B-type natriuretic peptide for treatment of heart failure: a dying therapy reborn?” J Am Coll Cardiol 60, no. 22 (December 4, 2012): 2313–15. https://doi.org/10.1016/j.jacc.2012.08.991.
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    • Shah, Ravi V., Steven McNulty, Christopher M. O’Connor, G Michael Felker, Eugene Braunwald, and Michael M. Givertz. “Effect of admission oral diuretic dose on response to continuous versus bolus intravenous diuretics in acute heart failure: an analysis from diuretic optimization strategies in acute heart failure.” Am Heart J 164, no. 6 (December 2012): 862–68. https://doi.org/10.1016/j.ahj.2012.08.019.
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    • Felker, G Michael, Marco Metra, Piotr Ponikowski, Adriaan A. Voors, Barry Greenberg, Germasimos Filippatos, Elaine Unemori, et al. “Changes in Troponin I and Outcomes in Acute Heart Failure: Data from the PreRELAX study.” Circulation 126, no. 21 (November 20, 2012).
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    • Ahmad, Tariq, Mona Fiuzat, Susanna Stevens, Kirkwood F. Adams, David J. Whellan, Mark P. Donahue, Dalane W. Kitzman, et al. “Elevated Galectin-3 Levels and Prediction of Mode of Death in Heart Failure: Insights from the HF-ACTION Study.” Circulation 126, no. 21 (November 20, 2012).
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    • Gupta, Achal, Eugene Braunwald, Steven McNulty, G Michael Felker, E Michael Gilbert, Rami Alharethi, Kerry L. Lee, et al. “Obesity and the response to intensified diuretic treatment in decompensated heart failure: a DOSE trial substudy.” J Card Fail 18, no. 11 (November 2012): 837–44. https://doi.org/10.1016/j.cardfail.2012.09.005.
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    • Patel, C. B., J. Suarez, G. M. Felker, R. Becker, A. F. Hernandez, and J. G. Rogers. “Response to letter regarding article, mechanisms of bleeding and approach to patients with axial-flow left ventricular assist devices.” Circulation: Heart Failure 5, no. 6 (November 1, 2012). https://doi.org/10.1161/CIRCHEARTFAILURE.112.971283.
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    • Felker, G Michael, Vic Hasselblad, WH Wilson Tang, Adrian F. Hernandez, Paul W. Armstrong, Gregg C. Fonarow, Adriaan A. Voors, et al. “Troponin I in acute decompensated heart failure: insights from the ASCEND-HF study.” Eur J Heart Fail 14, no. 11 (November 2012): 1257–64. https://doi.org/10.1093/eurjhf/hfs110.
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    • Felker, G. M., and R. J. Mentz. “Reply.” Journal of the American College of Cardiology 60, no. 17 (October 23, 2012): 1713–14. https://doi.org/10.1016/j.jacc.2012.07.023.
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    • Ahmad, Tariq, and G Michael Felker. “Galectin-3 in heart failure: more answers or more questions?” J Am Heart Assoc 1, no. 5 (October 2012): e004374. https://doi.org/10.1161/JAHA.112.004374.
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    • Subherwal, Sumeet, Kevin J. Anstrom, William S. Jones, Michael G. Felker, Sanjay Misra, Michael S. Conte, William R. Hiatt, and Manesh R. Patel. “Use of alternative methodologies for evaluation of composite end points in trials of therapies for critical limb ischemia.” Am Heart J 164, no. 3 (September 2012): 277–84. https://doi.org/10.1016/j.ahj.2012.07.002.
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    • Ahmad, Tariq, and G Michael Felker. “ACP Journal Club: warfarin and aspirin did not differ for death or stroke in heart failure and sinus rhythm.” Ann Intern Med 157, no. 4 (August 21, 2012): JC2–7. https://doi.org/10.7326/0003-4819-157-4-201208210-02007.
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    • Lazzarini, Valentina, and G Michael Felker. “Management of the cardiorenal syndrome in acute heart failure.” Curr Treat Options Cardiovasc Med 14, no. 4 (August 2012): 342–55. https://doi.org/10.1007/s11936-012-0186-5.
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    • Metra, Marco, Luca Bettari, Franca Pagani, Valentina Lazzarini, Carlo Lombardi, Valentina Carubelli, Graziella Bonetti, et al. “Troponin T levels in patients with acute heart failure: clinical and prognostic significance of their detection and release during hospitalisation.” Clin Res Cardiol 101, no. 8 (August 2012): 663–72. https://doi.org/10.1007/s00392-012-0441-5.
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    • Eapen, Zubin J., WH Wilson Tang, G Michael Felker, Adrian F. Hernandez, Kenneth W. Mahaffey, A Michael Lincoff, and Matthew T. Roe. “Defining heart failure end points in ST-segment elevation myocardial infarction trials: integrating past experiences to chart a path forward.” Circ Cardiovasc Qual Outcomes 5, no. 4 (July 1, 2012): 594–600. https://doi.org/10.1161/CIRCOUTCOMES.112.966150.
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    • Felker, G Michael, and Robert J. Mentz. “Diuretics and ultrafiltration in acute decompensated heart failure.” J Am Coll Cardiol 59, no. 24 (June 12, 2012): 2145–53. https://doi.org/10.1016/j.jacc.2011.10.910.
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    • Mentz, Robert J., Mona Fiuzat, Linda K. Shaw, Harry R. Phillips, Salvador Borges-Neto, G Michael Felker, and Christopher M. O’Connor. “Comparison of Clinical characteristics and long-term outcomes of patients with ischemic cardiomyopathy with versus without angina pectoris (from the Duke Databank for Cardiovascular Disease).” Am J Cardiol 109, no. 9 (May 1, 2012): 1272–77. https://doi.org/10.1016/j.amjcard.2011.12.021.
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    • Allen, Larry A., Lynne W. Stevenson, Kathleen L. Grady, Nathan E. Goldstein, Daniel D. Matlock, Robert M. Arnold, Nancy R. Cook, et al. “Decision making in advanced heart failure: a scientific statement from the American Heart Association.” Circulation 125, no. 15 (April 17, 2012): 1928–52. https://doi.org/10.1161/CIR.0b013e31824f2173.
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    • Ahmad, Tariq, Mona Fiuzat, G Michael Felker, and Christopher O’Connor. “Novel biomarkers in chronic heart failure.” Nat Rev Cardiol 9, no. 6 (March 27, 2012): 347–59. https://doi.org/10.1038/nrcardio.2012.37.
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    • Bart, Bradley A., Steven R. Goldsmith, Kerry L. Lee, Margaret M. Redfield, G Michael Felker, Christopher M. O’Connor, Horng H. Chen, et al. “Cardiorenal rescue study in acute decompensated heart failure: rationale and design of CARRESS-HF, for the Heart Failure Clinical Research Network.” J Card Fail 18, no. 3 (March 2012): 176–82. https://doi.org/10.1016/j.cardfail.2011.12.009.
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    • Felker, G Michael. “Loop diuretics in heart failure.” Heart Fail Rev 17, no. 2 (March 2012): 305–11. https://doi.org/10.1007/s10741-011-9245-3.
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    • Metra, M., J. R. Teerlink, G. M. Felker, B. H. Greenberg, G. Filippatos, P. Ponikowski, S. L. Teichman, et al. “Erratum: Flexible diuretic titration in chronic heart failure: Where is the evidence? (Journal of Cardiac Failure (2011) 17 (944-954)).” Journal of Cardiac Failure 18, no. 2 (February 1, 2012): 172. https://doi.org/10.1016/j.cardfail.2012.01.012.
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    • Ponikowski, Piotr, Marco Metra, John R. Teerlink, Elaine Unemori, G Michael Felker, Adriaan A. Voors, Gerasimos Filippatos, et al. “Design of the RELAXin in acute heart failure study.” Am Heart J 163, no. 2 (February 2012): 149-55.e1. https://doi.org/10.1016/j.ahj.2011.10.009.
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    • Bettari, Luca, Mona Fiuzat, Linda K. Shaw, Daniel M. Wojdyla, Marco Metra, G Michael Felker, and Christopher M. O’Connor. “Hyponatremia and long-term outcomes in chronic heart failure--an observational study from the Duke Databank for Cardiovascular Diseases.” J Card Fail 18, no. 1 (January 2012): 74–81. https://doi.org/10.1016/j.cardfail.2011.09.005.
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    • Dev, Sandesh, Robert M. Clare, G Michael Felker, Mona Fiuzat, Lynne Warner Stevenson, and Christopher M. O’Connor. “Link between decisions regarding resuscitation and preferences for quality over length of life with heart failure.” Eur J Heart Fail 14, no. 1 (January 2012): 45–53. https://doi.org/10.1093/eurjhf/hfr142.
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    • Dev, Sandesh, Shailesh C. Shirolkar, Susanna R. Stevens, Linda K. Shaw, Patricia A. Adams, G Michael Felker, Joseph G. Rogers, and Christopher M. O’Connor. “Reduction in body weight but worsening renal function with late ultrafiltration for treatment of acute decompensated heart failure.” Cardiology 123, no. 3 (2012): 145–53. https://doi.org/10.1159/000342457.
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    • Felker, G Michael, Mona Fiuzat, Linda K. Shaw, Robert Clare, David J. Whellan, Luca Bettari, Shailesh C. Shirolkar, et al. “Galectin-3 in ambulatory patients with heart failure: results from the HF-ACTION study.” Circ Heart Fail 5, no. 1 (January 2012): 72–78. https://doi.org/10.1161/CIRCHEARTFAILURE.111.963637.
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    • Metra, M., L. Bettari, F. Pagani, V. Lazzarini, C. Lombardi, V. Carubelli, G. Bonetti, et al. “Troponin T levels in patients with acute heart failure: Clinical and prognostic significance of their detection and release during hospitalisation.” Clinical Research in Cardiology 101, no. 8 (2012): 663–72. https://doi.org/10.1007/s00392-012-0441-599.
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    • Ahmad, Tariq, Robert J. Mentz, G Michael Felker, Carmelo A. Milano, Joseph G. Rogers, and Chetan B. Patel. “Recurrence of heart failure symptoms after LVAD placement due to bradycardia-induced inflow obstruction.” J Heart Lung Transplant 31, no. 1 (January 2012): 111–13. https://doi.org/10.1016/j.healun.2011.09.002.
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    • Bettari, Luca, Mona Fiuzat, Gary M. Felker, and Christopher M. O’Connor. “Significance of hyponatremia in heart failure.” Heart Fail Rev 17, no. 1 (January 2012): 17–26. https://doi.org/10.1007/s10741-010-9193-3.
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    • Metra, M., J. R. Teerlink, G. M. Felker, B. H. Greenberg, G. Filippatos, P. Ponikowslci, S. L. Teichman, et al. “Flexible Diuretic Titration in Chronic Heart Failure: Where Is the Evidence? (vol 17, pg 944, 2011).” Journal of Cardiac Failure 18, no. 2 (2012): 172–172.
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    • Felker, G Michael, WH Wilson Tang, Adrian F. Hernandez, Vic Hasselblad, Paul W. Armstrong, Gregg C. Fonarow, Adriaan A. Voors, et al. “High Sensitivity Troponin I in Acute Decompensated Heart Failure: Insights from the ASCEND-HF Study.” Circulation 124, no. 21 (November 22, 2011).
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    • Kociol, Robb D., Steven E. McNulty, Kerry L. Lee, Fred S. Apple, Russell P. Tracy, Adrian F. Hernandez, Robert J. Mentz, Eugene Braunwald, Christopher M. O’Connor, and G Michael Felker. “Circulating Cardiac Troponin I as Detected By a High-Sensitivity Assay among Patients Hospitalized with Acute Decompensated Heart Failure.” Circulation 124, no. 21 (November 22, 2011).
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    • Ohtani, Tomohito, G Michael Felker, Steven E. McNulty, Martin M. LeWinter, Eugene Braunwald, and Margaret M. Redfield. “Plasma Renin Activity on Admission Predicts Diuretic Resistance and Poor Outcomes in Acute Decompensated Heart Failure: An Ancillary Study of the Diuretic Optimization Strategies Evaluation Trial.” Circulation 124, no. 21 (November 22, 2011).
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    • Tang, WH Wilson, G Michael Felker, Adrian F. Hernandez, Amy P. Hsu, Stephen S. Gottlieb, Adriaan A. Voors, Javed Butler, et al. “Baseline Cystatin C is Associated with Short-Term Adverse Events in Acute Heart Failure but Does Not Predict Treatment Effects with Nesiritide Therapy.” Circulation 124, no. 21 (November 22, 2011).
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    • Suarez, Jorge, Chetan B. Patel, G Michael Felker, Richard Becker, Adrian F. Hernandez, and Joseph G. Rogers. “Mechanisms of bleeding and approach to patients with axial-flow left ventricular assist devices.” Circ Heart Fail 4, no. 6 (November 2011): 779–84. https://doi.org/10.1161/CIRCHEARTFAILURE.111.962613.
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    • Felker, G Michael. “Biomarkers as surrogate end points in heart failure trials.” Heart Fail Clin 7, no. 4 (October 2011): 501–7. https://doi.org/10.1016/j.hfc.2011.06.001.
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    • Piacentino, Valentino, Constantine D. Troupes, Asvin M. Ganapathi, Laura J. Blue, G Burkhard Mackensen, Madhav Swaminathan, G Michael Felker, et al. “Clinical impact of concomitant tricuspid valve procedures during left ventricular assist device implantation.” Ann Thorac Surg 92, no. 4 (October 2011): 1414–18. https://doi.org/10.1016/j.athoracsur.2011.05.084.
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    • Hernandez, Adrian F., and G Michael Felker. “Advanced heart failure.” Prog Cardiovasc Dis 54, no. 2 (September 2011): 77. https://doi.org/10.1016/j.pcad.2011.07.001.
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    • Kociol, Robb D., John R. Horton, Gregg C. Fonarow, Eric M. Reyes, Linda K. Shaw, Christopher M. O’Connor, G Michael Felker, and Adrian F. Hernandez. “Admission, discharge, or change in B-type natriuretic peptide and long-term outcomes: data from Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure (OPTIMIZE-HF) linked to Medicare claims.” Circ Heart Fail 4, no. 5 (September 2011): 628–36. https://doi.org/10.1161/CIRCHEARTFAILURE.111.962290.
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    • Voors, Adriaan A., Beth A. Davison, G Michael Felker, Piotr Ponikowski, Elaine Unemori, Gadi Cotter, John R. Teerlink, et al. “Early drop in systolic blood pressure and worsening renal function in acute heart failure: renal results of Pre-RELAX-AHF.” Eur J Heart Fail 13, no. 9 (September 2011): 961–67. https://doi.org/10.1093/eurjhf/hfr060.
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    • Davison, Beth A., Gad Cotter, Hengrui Sun, Li Chen, John R. Teerlink, Marco Metra, G Michael Felker, et al. “Permutation criteria to evaluate multiple clinical endpoints in a proof-of-concept study: lessons from Pre-RELAX-AHF.” Clin Res Cardiol 100, no. 9 (September 2011): 745–53. https://doi.org/10.1007/s00392-011-0304-5.
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    • Bettari, L., M. Fiuzat, D. Wojdyla, L. Shaw, M. Metra, G. M. Felker, and C. O’Connor. “The independent prognostic value of hyponatremia in a cohort of heart failure patients: analysis from the Duke databank for cardiovascular disease.” European Heart Journal 32 (August 1, 2011): 134–134.
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    • Bennett-Gittens, Raquel L., Javed Butler, Steve E. McNulty, Anekwe Onwuanyi, Adefisayo Oduwole, Mike Felker, Adrian F. Hernandez, Kerry L. Lee, Brenda Lankford, and Elizabeth O. Ofili. “Cystatin C as a Biomarker of Worsening Renal Function in Acute Heart Failure: Insights from the DOSE Study.” Journal of Cardiac Failure 17, no. 8 (August 2011): S58–S58. https://doi.org/10.1016/j.cardfail.2011.06.197.
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    • Ohtani, Tomohito, G Michael Felker, Steven E. McNulty, Martin M. LeWinter, Eugene Braunwald, and Margaret M. Redfield. “Plasma Renin Activity (PRA) Predicts Diuretic Resistance in Acute Heart Failure Patients: An Ancillary Study of the Diuretic Optimization Strategies Evaluation in Acute Heart Failure (DOSE-AHF).” Journal of Cardiac Failure 17, no. 8 (August 2011): S25–26. https://doi.org/10.1016/j.cardfail.2011.06.087.
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    • Patel, C., R. J. Mentz, J. Suarez, A. F. Hernandez, G. M. Felker, C. M. O’Connor, and J. G. Rogers. “Association between VE-VCO2 Slope and Resting Hemodynamic Measurements in Ambulatory Heart Failure (HF) Patients: An Analysis from the Duke Advanced HF Database.” Journal of Cardiac Failure 17, no. 8 (August 2011): S8–9. https://doi.org/10.1016/j.cardfail.2011.06.026.
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    • Shirolkar, Shailesh C., G Michael Felker, Susanna R. Stevens, Minnie P. Blackwell, Shelley L. Thompson, Joseph G. Rogers, Christopher M. O’Connor, and Sandesh Dev. “Ultrafiltration is Associated with Worsening Renal Function, and Electrolyte Abnormalities in Patients with Diuretic Refractory Heart Failure and Renal Dysfunction.” Journal of Cardiac Failure 17, no. 8 (August 2011): S96–S96. https://doi.org/10.1016/j.cardfail.2011.06.322.
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    • Felker, G. M. “Bolus and continuous/high- and low-dose diuretics had similar effects on symptoms and renal function in acute, decompensated HF.” Annals of Internal Medicine 155, no. 2 (July 19, 2011).
    • O’Connor, C. M., R. C. Starling, A. F. Hernandez, P. W. Armstrong, K. Dickstein, V. Hasselblad, G. M. Heizer, et al. “Effect of nesiritide in patients with acute decompensated heart failure.” N Engl J Med 365, no. 1 (July 7, 2011): 32–43. https://doi.org/10.1056/NEJMoa1100171.
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    • Felker, G Michael, Eugene Braunwald, and Christopher M. O’Connor. “Diuretic Strategies in Patients with Acute Heart Failure REPLY.” New England Journal of Medicine 364, no. 21 (May 26, 2011): 2069–2069.
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    • Brain, Joseph D., and Costas A. Christophi. “Heterogeneity of hemoglobin H disease in childhood.” N Engl J Med 364, no. 21 (May 26, 2011): 2069–70. https://doi.org/10.1056/NEJMc1103406.
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    • Bettari, Luca, Mona Fiuzat, Richard Becker, G Michael Felker, Marco Metra, and Christopher M. O’Connor. “Thromboembolism and antithrombotic therapy in patients with heart failure in sinus rhythm: current status and future directions.” Circ Heart Fail 4, no. 3 (May 2011): 361–68. https://doi.org/10.1161/CIRCHEARTFAILURE.110.959957.
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    • Milo-Cotter, Olga, G Michael Felker, Nir Uriel, Edo Kaluski, Christopher Edwards, Michele M. Rund, Beth Davison Weatherley, and Gad Cotter. “Patterns of leukocyte counts on admissions for acute heart failure--presentation and outcome--results from a community based registry.” Int J Cardiol 148, no. 1 (April 1, 2011): 17–22. https://doi.org/10.1016/j.ijcard.2009.10.009.
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    • Felker, G Michael, Kerry L. Lee, David A. Bull, Margaret M. Redfield, Lynne W. Stevenson, Steven R. Goldsmith, Martin M. LeWinter, et al. “Diuretic strategies in patients with acute decompensated heart failure.” N Engl J Med 364, no. 9 (March 3, 2011): 797–805. https://doi.org/10.1056/NEJMoa1005419.
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    • Mentz, Robert J., and G Michael Felker. “Natriuretic Peptide-guided therapy for heart failure.” Circ J 75, no. 9 (2011): 2031–37. https://doi.org/10.1253/circj.cj-11-0660.
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    • Adams, Kirkwood F., Mandeep R. Mehra, Ron M. Oren, Christopher M. O’Connor, Jun R. Chiong, Jalal K. Ghali, Daniel J. Lenihan, et al. “Prospective evaluation of the association between cardiac troponin T and markers of disturbed erythropoiesis in patients with heart failure.” Am Heart J 160, no. 6 (December 2010): 1142–48. https://doi.org/10.1016/j.ahj.2010.07.033.
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    • Felker, G. M. “Acute Decompensated Heart Failure,” December 1, 2010, 157–62. https://doi.org/10.1016/B978-0-323-04525-4.00023-X.
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    • Fiuzat, Mona, Linda K. Shaw, Laine Thomas, G Michael Felker, and Christopher M. O’Connor. “United States stock market performance and acute myocardial infarction rates in 2008-2009 (from the Duke Databank for Cardiovascular Disease).” Am J Cardiol 106, no. 11 (December 1, 2010): 1545–49. https://doi.org/10.1016/j.amjcard.2010.07.027.
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    • Deswal, Anita, Biykem Bozkurt, Allison Pritchett, G. M. Felker, Steven McNulty, Kerry Lee, Eugene Braunwald, and Margaret M. Redfield. “Worsening Renal Function in Hospitalized Heart Failure Patients with Preserved vs. Reduced Ejection Fraction.” Circulation 122, no. 21 (November 23, 2010).
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    • Metra, Marco, G Michael Felker, Valerio Zacà, Silvia Bugatti, Carlo Lombardi, Luca Bettari, Adrian A. Voors, Mihai Gheorghiade, and Livio Dei Cas. “Acute heart failure: multiple clinical profiles and mechanisms require tailored therapy.” Int J Cardiol 144, no. 2 (October 8, 2010): 175–79. https://doi.org/10.1016/j.ijcard.2010.04.003.
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    • Felker, G Michael. “Coenzyme Q10 and statins in heart failure: the dog that didn't bark.” J Am Coll Cardiol 56, no. 15 (October 5, 2010): 1205–6. https://doi.org/10.1016/j.jacc.2010.03.088.
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    • Metra, Marco, John R. Teerlink, G Michael Felker, Barry H. Greenberg, Gerasimos Filippatos, Piotr Ponikowski, Sam L. Teichman, et al. “Dyspnoea and worsening heart failure in patients with acute heart failure: results from the Pre-RELAX-AHF study.” Eur J Heart Fail 12, no. 10 (October 2010): 1130–39. https://doi.org/10.1093/eurjhf/hfq132.
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    • Kociol, Robb D., Peter S. Pang, Mihai Gheorghiade, Gregg C. Fonarow, Christopher M. O’Connor, and G Michael Felker. “Troponin elevation in heart failure prevalence, mechanisms, and clinical implications.” J Am Coll Cardiol 56, no. 14 (September 28, 2010): 1071–78. https://doi.org/10.1016/j.jacc.2010.06.016.
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    • Felker, G Michael, and Alan S. Maisel. “A global rank end point for clinical trials in acute heart failure.” Circ Heart Fail 3, no. 5 (September 2010): 643–46. https://doi.org/10.1161/CIRCHEARTFAILURE.109.926030.
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    • Adams, Kirkwood F., G Michael Felker, Ghassan Fraij, J Herbert Patterson, and Christopher M. O’Connor. “Biomarker guided therapy for heart failure: focus on natriuretic peptides.” Heart Fail Rev 15, no. 4 (July 2010): 351–70. https://doi.org/10.1007/s10741-009-9139-9.
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    • Michael Felker, G. “Diuretic management in heart failure.” Congest Heart Fail 16 Suppl 1 (July 2010): S68–72. https://doi.org/10.1111/j.1751-7133.2010.00172.x.
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    • Allen, Larry A., and G Michael Felker. “Multi-marker strategies in heart failure: clinical and statistical approaches.” Heart Fail Rev 15, no. 4 (July 2010): 343–49. https://doi.org/10.1007/s10741-009-9144-z.
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    • Felker, G Michael, Peter S. Pang, Kirkwood F. Adams, John G. F. Cleland, Gad Cotter, Kenneth Dickstein, Gerasimos S. Filippatos, et al. “Clinical trials of pharmacological therapies in acute heart failure syndromes: lessons learned and directions forward.” Circ Heart Fail 3, no. 2 (March 2010): 314–25. https://doi.org/10.1161/CIRCHEARTFAILURE.109.893222.
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    • Allen, Larry A., G Michael Felker, Mandeep R. Mehra, Jun R. Chiong, Stephanie H. Dunlap, Jalal K. Ghali, Daniel J. Lenihan, et al. “Validation and potential mechanisms of red cell distribution width as a prognostic marker in heart failure.” J Card Fail 16, no. 3 (March 2010): 230–38. https://doi.org/10.1016/j.cardfail.2009.11.003.
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    • Kimmenade, Roland R. J. van, Asim A. Mohammed, Shanmugam Uthamalingam, Peter van der Meer, G Michael Felker, and James L. Januzzi. “Red blood cell distribution width and 1-year mortality in acute heart failure.” Eur J Heart Fail 12, no. 2 (February 2010): 129–36. https://doi.org/10.1093/eurjhf/hfp179.
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    • Szczech, Lynda A., Huiman X. Barnhart, Shelly Sapp, G Michael Felker, Adrian Hernandez, Donal Reddan, Robert M. Califf, Jula K. Inrig, Uptal D. Patel, and Ajay K. Singh. “A secondary analysis of the CHOIR trial shows that comorbid conditions differentially affect outcomes during anemia treatment.” Kidney Int 77, no. 3 (February 2010): 239–46. https://doi.org/10.1038/ki.2009.415.
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    • Felker, G Michael. “Too much, too little, or just right?: untangling endogenous erythropoietin in heart failure.” Circulation 121, no. 2 (January 19, 2010): 191–93. https://doi.org/10.1161/CIRCULATIONAHA.109.915504.
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    • Felker, G. M., and J. R. Teerlink. “Clinical Trial Design in Heart Failure,” January 1, 2010, 570–93. https://doi.org/10.1016/B978-1-4160-5895-3.10039-7.
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    • Milo-Cotter, Olga, John R. Teerlink, Marco Metra, G Michael Felker, Piotr Ponikowski, Adriaan A. Voors, Christopher Edwards, et al. “Low lymphocyte ratio as a novel prognostic factor in acute heart failure: results from the Pre-RELAX-AHF study.” Cardiology 117, no. 3 (2010): 190–96. https://doi.org/10.1159/000321416.
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    • Allen, Larry A., Kevin J. Anstrom, John R. Horton, Linda K. Shaw, Eric L. Eisenstein, and G Michael Felker. “Relationship between anemia and health care costs in heart failure.” J Card Fail 15, no. 10 (December 2009): 843–49. https://doi.org/10.1016/j.cardfail.2009.06.435.
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    • Adams, Kirkwood F., Ileana L. Piña, Jalal K. Ghali, Lynne E. Wagoner, Stephanie H. Dunlap, Todd A. Schwartz, Wendy Gattis Stough, et al. “Prospective evaluation of the association between hemoglobin concentration and quality of life in patients with heart failure.” Am Heart J 158, no. 6 (December 2009): 965–71. https://doi.org/10.1016/j.ahj.2009.10.015.
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    • Metra, Marco, John R. Teerlink, Adriaan A. Voors, G Michael Felker, Olga Milo-Cotter, Beth Weatherley, Howard Dittrich, and Gad Cotter. “Vasodilators in the treatment of acute heart failure: what we know, what we don't.” Heart Fail Rev 14, no. 4 (December 2009): 299–307. https://doi.org/10.1007/s10741-008-9127-5.
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    • Teichman, Sam L., Elaine Unemori, Thomas Dschietzig, Kirk Conrad, Adriaan A. Voors, John R. Teerlink, G Michael Felker, Marco Metra, and Gad Cotter. “Relaxin, a pleiotropic vasodilator for the treatment of heart failure.” Heart Fail Rev 14, no. 4 (December 2009): 321–29. https://doi.org/10.1007/s10741-008-9129-3.
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    • Volz, Elizabeth M., and G Michael Felker. “How to use diuretics in heart failure.” Curr Treat Options Cardiovasc Med 11, no. 6 (December 2009): 426–32. https://doi.org/10.1007/s11936-009-0045-1.
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    • Pal, Jay D., Valentino Piacentino, Angela D. Cuevas, Tim Depp, Mani A. Daneshmand, Adrian F. Hernandez, G Michael Felker, Andrew J. Lodge, Joseph G. Rogers, and Carmelo A. Milano. “Impact of left ventricular assist device bridging on posttransplant outcomes.” Ann Thorac Surg 88, no. 5 (November 2009): 1457–61. https://doi.org/10.1016/j.athoracsur.2009.07.021.
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    • Weatherley, Beth Davison, Olga Milo-Cotter, G Michael Felker, Nir Uriel, Edo Kaluski, Zvi Vered, Christopher M. O’Connor, Kirkwood F. Adams, and Gad Cotter. “Early worsening heart failure in patients admitted with acute heart failure--a new outcome measure associated with long-term prognosis?” Fundam Clin Pharmacol 23, no. 5 (October 2009): 633–39. https://doi.org/10.1111/j.1472-8206.2009.00697.x.
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    • Felker, G Michael, David Whellan, William E. Kraus, Robert Clare, Faiez Zannad, Mark Donahue, Kirkwood Adams, et al. “N-terminal pro-brain natriuretic peptide and exercise capacity in chronic heart failure: data from the Heart Failure and a Controlled Trial Investigating Outcomes of Exercise Training (HF-ACTION) study.” Am Heart J 158, no. 4 Suppl (October 2009): S37–44. https://doi.org/10.1016/j.ahj.2009.07.011.
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    • Felker, G Michael, Vic Hasselblad, Adrian F. Hernandez, and Christopher M. O’Connor. “Biomarker-guided therapy in chronic heart failure: a meta-analysis of randomized controlled trials.” Am Heart J 158, no. 3 (September 2009): 422–30. https://doi.org/10.1016/j.ahj.2009.06.018.
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    • Felker, G. M., J. R. Teerlink, P. Ponikowski, A. A. Voors, G. Filippatos, B. H. Greenberg, S. L. Teichman, G. Cotter, B. D. Weatherley, and M. Metra. “Time to treatment and vasodilator efficacy in acute heart failure: Results from the Pre-RELAX-AHF study.” European Heart Journal 30 (September 1, 2009): 424–424.
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    • Metra, M., J. R. Teerlink, A. A. Voors, G. M. Felker, P. Ponikowski, B. D. Weatherley, G. S. Filippatos, E. Unemori, S. Teichman, and G. Cotter. “Effects of the new vasodilator relaxin for the treatment of patients with acute heart failure and normal to elevated blood pressure: results of a phase 2b study (Pre-RELAX-AHF).” European Heart Journal 30 (September 1, 2009): 424–25.
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    • Teerlink, J. R., M. Metra, A. A. Voors, G. M. Felker, P. Ponikowski, G. S. Filippatos, B. H. Greenberg, S. L. Teichman, B. D. Weatherley, and G. Cotter. “Increased symptom-improvement with the novel vasodilator, relaxin, in Acute Heart Failure (AHF) patients with elevated blood pressure. Results from the Pre-RELAX-AHF study.” European Heart Journal 30 (September 1, 2009): 164–164.
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    • Teichman, S., E. Unemori, M. Metra, J. R. Teerlink, A. A. Voors, G. M. Felker, P. Ponikowski, B. Weatherley, G. Filippatos, and G. Cotter. “Patient-reported dyspnea in acute heart failure trials. Use of the Likert and the visual analog scales in the pre-RELAX AHF study.” European Heart Journal 30 (September 1, 2009): 445–46.
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    • Voors, A. A., G. M. Felker, M. Metra, J. R. Teerlink, P. Ponikowski, B. H. Greenberg, E. Unimori, G. Filippatos, G. Cotter, and S. L. Teichman. “Worsening renal function in acute heart failure: change in BP and effects of relaxin.” European Heart Journal 30 (September 1, 2009): 1020–21.
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    • Weatherley, B Davison, G. Cotter, G. M. Felker, J. R. Teerlink, G. Filippatos, B. Greenberg, A. Voors, M. Metra, S. L. Teichman, and E. Unemori. “Early in-ospital worsening heart failure predicts adverse outcome in patients.” European Heart Journal 30 (September 1, 2009): 719–719.
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    • Felker, G Michael, Adriaan A. Voors, Marco Metra, John R. Teerlink, Piotr Ponikowski, Barry H. Greenberg, Elaine Unemori, Gad Cotter, and Sam L. Teichman. “Worsening Renal Function in Acute Heart Failure: Change in Blood Pressure and Effects of Relaxin.” Journal of Cardiac Failure 15, no. 6 (August 2009): S63–S63. https://doi.org/10.1016/j.cardfail.2009.06.194.
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    • Felker, G Michael, John R. Teerlink, Piotr Ponikowski, Adriaan A. Voors, Gerasimos Filippatos, Barry H. Greenberg, Sam L. Teichman, Gad Cotter, Beth D. Weatherley, and Marco Metra. “Time to Treatment and Vasodilator Efficacy in Acute Heart Failure: Results from the Pre-RELAX-AHF Study.” Journal of Cardiac Failure 15, no. 6 (August 2009): S68–S68. https://doi.org/10.1016/j.cardfail.2009.06.210.
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    • Metra, Marco, John R. Teerlink, Beth D. Weatherley, Barry H. Greenberg, G Michael Felker, Piotr Ponikowski, Adrian A. Voors, et al. “Changes in Dyspnea during Treatment of Acute Heart Failure Are Correlated with Clinical Signs, Rehospitalizations and Mortality. Results from the Pre-RELAX-AHF Trial.” Journal of Cardiac Failure 15, no. 6 (August 2009): S62–63. https://doi.org/10.1016/j.cardfail.2009.06.190.
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    • Teerlink, John R., Marco Metra, G Michael Felker, Adriaan A. Voors, Barry H. Greenberg, Piotr Ponikowski, Sam L. Teichman, and Gad Cotter. “Vasodilators in Acute Heart Failure (AHF): Does Blood Pressure Matter? Results from Pre-Relax-AHF.” Journal of Cardiac Failure 15, no. 6 (August 2009): S74–S74. https://doi.org/10.1016/j.cardfail.2009.06.169.
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    • Fiuzat, Mona, G Michael Felker, Mark P. Donahue, and Christopher M. O’Connor. “Using genetic information to select treatment for patients with heart failure: has the time come?” Per Med 6, no. 4 (July 2009): 385–92. https://doi.org/10.2217/pme.09.19.
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    • Adams, K. F., J. H. Patterson, R. M. Oren, M. R. Mehra, C. M. O’Connor, I. L. Pina, A. B. Miller, et al. “Prospective assessment of the occurrence of anemia in patients with heart failure: Results from the Study of Anemia in a Heart Failure Population (STAMINA-HFP) Registry (vol 157, pg 926, 2009).” American Heart Journal 158, no. 1 (July 1, 2009): 77–77.
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    • Allen, Larry A., Adrian F. Hernandez, Christopher M. O’Connor, and G Michael Felker. “End points for clinical trials in acute heart failure syndromes.” J Am Coll Cardiol 53, no. 24 (June 16, 2009): 2248–58. https://doi.org/10.1016/j.jacc.2008.12.079.
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    • Gheorghiade, Mihai, Kirkwood F. Adams, John G. F. Cleland, Gad Cotter, G Michael Felker, Gerasimos S. Filippatos, Gregg C. Fonarow, et al. “Phase III clinical trial end points in acute heart failure syndromes: a virtual roundtable with the Acute Heart Failure Syndromes International Working Group.” Am Heart J 157, no. 6 (June 2009): 957–70. https://doi.org/10.1016/j.ahj.2009.04.010.
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    • Adams, Kirkwood F., James H. Patterson, Ron M. Oren, Mandeep R. Mehra, Christopher M. O’Connor, Ileana L. Piña, Alan B. Miller, et al. “Prospective assessment of the occurrence of anemia in patients with heart failure: results from the Study of Anemia in a Heart Failure Population (STAMINA-HFP) Registry.” Am Heart J 157, no. 5 (May 2009): 926–32. https://doi.org/10.1016/j.ahj.2009.01.012.
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    • Teerlink, John R., Marco Metra, G Michael Felker, Piotr Ponikowski, Adriaan A. Voors, Beth Davison Weatherley, Alon Marmor, et al. “Relaxin for the treatment of patients with acute heart failure (Pre-RELAX-AHF): a multicentre, randomised, placebo-controlled, parallel-group, dose-finding phase IIb study.” Lancet 373, no. 9673 (April 25, 2009): 1429–39. https://doi.org/10.1016/S0140-6736(09)60622-X.
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    • Allen, Larry A., Kevin J. Anstrom, John Horton, Linda K. Shaw, Eric L. Eisenstein, and G Michael Felker. “Relationship Between Anemia Status and Health Care Costs in Patients With Symptomatic Heart Failure.” Journal of the American College of Cardiology 53, no. 10 (March 10, 2009): A391–A391.
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    • Felker, Gary Michael, Victor Hasselblad, and Christopher M. O’Connor. “Biomarker Guided Therapy in Chronic Heart Failure: A Meta-Analysis of Randomized Controlled Trials.” Journal of the American College of Cardiology 53, no. 10 (March 10, 2009): A155–A155.
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    • Felker, Gary Michael, Faiez Zannad, Mark Donahue, Kirkwood F. Adams, Robert McKelvie, Robert Claire, William E. Kraus, David Whellan, Ileana Pina, and Christopher M. O’Connor. “Relationship Between NTproBNP and Exercise Capacity in Chronic Heart Failure: Baseline Data from the HF-ACTION Study.” Journal of the American College of Cardiology 53, no. 10 (March 10, 2009): A189–A189.
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    • Allen, Larry A., G Michael Felker, Stuart Pocock, John J. V. McMurray, Marc A. Pfeffer, Karl Swedberg, Duolao Wang, et al. “Liver function abnormalities and outcome in patients with chronic heart failure: data from the Candesartan in Heart Failure: Assessment of Reduction in Mortality and Morbidity (CHARM) program.” Eur J Heart Fail 11, no. 2 (February 2009): 170–77. https://doi.org/10.1093/eurjhf/hfn031.
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    • Felker, G Michael, Christopher M. O’Connor, Eugene Braunwald, and Eugene Heart Failure Clinical Research Network Investigators. “Loop diuretics in acute decompensated heart failure: necessary? Evil? A necessary evil?” Circ Heart Fail 2, no. 1 (January 2009): 56–62. https://doi.org/10.1161/CIRCHEARTFAILURE.108.821785.
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    • Milo-Cotter, Olga, Gad Cotter, Edo Kaluski, Michele M. Rund, G Michael Felker, Kirkwood F. Adams, Christopher M. O’Connor, and Beth Davison Weatherley. “Rapid clinical assessment of patients with acute heart failure: first blood pressure and oxygen saturation--is that all we need?” Cardiology 114, no. 1 (2009): 75–82. https://doi.org/10.1159/000213051.
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    • Allen, L. A., J. E. Yager, and G. M. Felker. “In reply.” Jama 300, no. 18 (November 12, 2008): 2117. https://doi.org/10.1001/jama.2008.552.
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    • Allen, Larry A., Marco Metra, Olga Milo-Cotter, Gerasimos Filippatos, Leonardo H. Reisin, Daniel R. Bensimhon, Edoardo G. Gronda, et al. “Improvements in signs and symptoms during hospitalization for acute heart failure follow different patterns and depend on the measurement scales used: an international, prospective registry to evaluate the evolution of measures of disease severity in acute heart failure (MEASURE-AHF).” J Card Fail 14, no. 9 (November 2008): 777–84. https://doi.org/10.1016/j.cardfail.2008.07.188.
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    • Rajagopal, Keshava, Brian Lima, Rebecca P. Petersen, Rachel G. Mesis, Mani A. Daneshmand, Anthony Lemaire, G Michael Felker, et al. “Infectious complications in extended criteria heart transplantation.” J Heart Lung Transplant 27, no. 11 (November 2008): 1217–21. https://doi.org/10.1016/j.healun.2008.08.001.
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    • Allen, Larry A., Jonathan E. Yager, Michele Jonsson Funk, Wayne C. Levy, James A. Tulsky, Margaret T. Bowers, Gwen C. Dodson, Christopher M. O’Connor, and G Michael Felker. “Discordance between patient-predicted and model-predicted life expectancy among ambulatory patients with heart failure.” Jama 299, no. 21 (June 4, 2008): 2533–42. https://doi.org/10.1001/jama.299.21.2533.
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    • Felker, G Michael, Kevin J. Anstrom, and Joseph G. Rogers. “A global ranking approach to end points in trials of mechanical circulatory support devices.” J Card Fail 14, no. 5 (June 2008): 368–72. https://doi.org/10.1016/j.cardfail.2008.01.009.
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    • Allen, Larry A., and G Michael Felker. “Advances in the surgical treatment of heart failure.” Curr Opin Cardiol 23, no. 3 (May 2008): 249–53. https://doi.org/10.1097/HCO.0b013e3282f54fea.
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    • Milo-Cotter, Olga, Gad Cotter, Beth D. Weatherley, Kirkwood F. Adams, Edo Kaluski, Nir Uriel, Christopher M. O’Connor, and G Michael Felker. “Hyponatraemia in acute heart failure is a marker of increased mortality but not when associated with hyperglycaemia.” Eur J Heart Fail 10, no. 2 (February 2008): 196–200. https://doi.org/10.1016/j.ejheart.2008.01.008.
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    • Petersen, John W., and G Michael Felker. “Inotropes in the management of acute heart failure.” Crit Care Med 36, no. 1 Suppl (January 2008): S106–11. https://doi.org/10.1097/01.CCM.0000296273.72952.39.
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    • Cotter, Gad, G Michael Felker, Kirkwood F. Adams, Olga Milo-Cotter, and Christopher M. O’Connor. “The pathophysiology of acute heart failure--is it all about fluid accumulation?” Am Heart J 155, no. 1 (January 2008): 9–18. https://doi.org/10.1016/j.ahj.2006.02.038.
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    • Felker, G Michael, Larry A. Allen, Stuart J. Pocock, Linda K. Shaw, John J. V. McMurray, Marc A. Pfeffer, Karl Swedberg, et al. “Red cell distribution width as a novel prognostic marker in heart failure: data from the CHARM Program and the Duke Databank.” J Am Coll Cardiol 50, no. 1 (July 3, 2007): 40–47. https://doi.org/10.1016/j.jacc.2007.02.067.
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    • Gheorghiade, Mihai, Marvin A. Konstam, John C. Burnett, Liliana Grinfeld, Aldo P. Maggioni, Karl Swedberg, James E. Udelson, et al. “Short-term clinical effects of tolvaptan, an oral vasopressin antagonist, in patients hospitalized for heart failure: the EVEREST Clinical Status Trials.” Jama 297, no. 12 (March 28, 2007): 1332–43. https://doi.org/10.1001/jama.297.12.1332.
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    • Milo-Cotter, Olga, Kirkwood F. Adams, Christopher M. O’Connor, Nir Uriel, Edo Kaluski, G Michael Felker, Beth Weatherley, Zvi Vered, and Gad Cotter. “Acute heart failure associated with high admission blood pressure--a distinct vascular disorder?” Eur J Heart Fail 9, no. 2 (February 2007): 178–83. https://doi.org/10.1016/j.ejheart.2006.06.004.
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    • Echols, Melvin R., G Michael Felker, Kevin L. Thomas, Karen S. Pieper, Jyotsna Garg, Michael S. Cuffe, Mihai Gheorghiade, Robert M. Califf, and Christopher M. O’Connor. “Racial differences in the characteristics of patients admitted for acute decompensated heart failure and their relation to outcomes: results from the OPTIME-CHF trial.” J Card Fail 12, no. 9 (December 2006): 684–88. https://doi.org/10.1016/j.cardfail.2006.08.003.
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    • Petersen, John W., and G Michael Felker. “Inflammatory biomarkers in heart failure.” Congest Heart Fail 12, no. 6 (November 2006): 324–28. https://doi.org/10.1111/j.1527-5299.2006.05595.x.
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    • Felker, G Michael, John W. Petersen, and Daniel B. Mark. “Natriuretic peptides in the diagnosis and management of heart failure.” Cmaj 175, no. 6 (September 12, 2006): 611–17. https://doi.org/10.1503/cmaj.060236.
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    • Leloudis, Dianne H., Michelle M. Kittleson, G Michael Felker, Paul B. Rosenberg, Adrian F. Hernandez, Jonathan E. Yager, and Stuart D. Russell. “Topical anesthesia with EMLA reduces pain during endomyocardial biopsy: a randomized trial.” J Heart Lung Transplant 25, no. 9 (September 2006): 1164–66. https://doi.org/10.1016/j.healun.2006.06.016.
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    • Lima, Brian, Keshava Rajagopal, Rebecca P. Petersen, Ashish S. Shah, Beth Soule, G Michael Felker, Joseph G. Rogers, Andrew J. Lodge, and Carmelo A. Milano. “Marginal cardiac allografts do not have increased primary graft dysfunction in alternate list transplantation.” Circulation 114, no. 1 Suppl (July 4, 2006): I27–32. https://doi.org/10.1161/CIRCULATIONAHA.105.000737.
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    • Felker, G Michael, and Gadi Cotter. “Unraveling the pathophysiology of acute heart failure: an inflammatory proposal.” Am Heart J 151, no. 4 (April 2006): 765–67. https://doi.org/10.1016/j.ahj.2005.07.004.
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    • Felker, G Michael, and Joseph G. Rogers. “Same bridge, new destinations rethinking paradigms for mechanical cardiac support in heart failure.” J Am Coll Cardiol 47, no. 5 (March 7, 2006): 930–32. https://doi.org/10.1016/j.jacc.2005.09.070.
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    • Milano, Carmelo A., Andrew J. Lodge, Laura J. Blue, Peter K. Smith, G Michael Felker, Adrian F. Hernandez, Paul B. Rosenberg, and Joseph G. Rogers. “Implantable left ventricular assist devices: new hope for patients with end-stage heart failure.” N C Med J 67, no. 2 (March 2006): 110–15.
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    • Felker, G Michael, Phillip S. Cuculich, and Mihai Gheorghiade. “The Valsalva maneuver: a bedside "biomarker" for heart failure.” Am J Med 119, no. 2 (February 2006): 117–22. https://doi.org/10.1016/j.amjmed.2005.06.059.
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    • Felker, G Michael, Linda K. Shaw, Wendy Gattis Stough, and Christopher M. O’Connor. “Anemia in patients with heart failure and preserved systolic function.” Am Heart J 151, no. 2 (February 2006): 457–62. https://doi.org/10.1016/j.ahj.2005.03.056.
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    • Felker, G Michael, Wendy Gattis Stough, Linda K. Shaw, and Christopher M. O’Connor. “Anaemia and coronary artery disease severity in patients with heart failure.” Eur J Heart Fail 8, no. 1 (January 2006): 54–57. https://doi.org/10.1016/j.ejheart.2005.05.004.
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    • Felker, G Michael, Carmelo A. Milano, Jonathan E. E. Yager, Adrian F. Hernandez, Laura Blue, Michael B. Higginbotham, Andrew J. Lodge, and Stuart D. Russell. “Outcomes with an alternate list strategy for heart transplantation.” J Heart Lung Transplant 24, no. 11 (November 2005): 1781–86. https://doi.org/10.1016/j.healun.2005.03.014.
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    • Yager, Jonathan E. E., Adrian F. Hernandez, Charles Steenbergen, Bradley Persing, Stuart D. Russell, Carmelo Milano, and G Michael Felker. “Recurrence of cardiac sarcoidosis in a heart transplant recipient.” J Heart Lung Transplant 24, no. 11 (November 2005): 1988–90. https://doi.org/10.1016/j.healun.2005.02.016.
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    • Klein, Liviu, Christopher M. O’Connor, Jeffrey D. Leimberger, Wendy Gattis-Stough, Ileana L. Piña, G Michael Felker, Kirkwood F. Adams, Robert M. Califf, Mihai Gheorghiade, and Mihai OPTIME-CHF Investigators. “Lower serum sodium is associated with increased short-term mortality in hospitalized patients with worsening heart failure: results from the Outcomes of a Prospective Trial of Intravenous Milrinone for Exacerbations of Chronic Heart Failure (OPTIME-CHF) study.” Circulation 111, no. 19 (May 17, 2005): 2454–60. https://doi.org/10.1161/01.CIR.0000165065.82609.3D.
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    • Kovacic, Jason C. “Further aspects of anemia, heart failure, and erythropoietin.” J Am Coll Cardiol 45, no. 9 (May 3, 2005): 1549–50. https://doi.org/10.1016/j.jacc.2005.02.023.
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    • Felker, G Michael. “The African-American heart failure trial: a new look at old drugs.” Future Cardiol 1, no. 3 (May 2005): 311–13. https://doi.org/10.1517/14796678.1.3.311.
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    • Felker, G Michael, Wendy A. Gattis, Kirkwood F. Adams, and Christopher M. O’Connor. “Reply.” Journal of the American College of Cardiology 45, no. 9 (May 2005): 1550–51. https://doi.org/10.1016/j.jacc.2005.02.022.
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    • Gheorghiade, Mihai, Cesare Orlandi, John C. Burnett, David Demets, Liliana Grinfeld, Aldo Maggioni, Karl Swedberg, et al. “Rationale and design of the multicenter, randomized, double-blind, placebo-controlled study to evaluate the Efficacy of Vasopressin antagonism in Heart Failure: Outcome Study with Tolvaptan (EVEREST).” J Card Fail 11, no. 4 (May 2005): 260–69. https://doi.org/10.1016/j.cardfail.2005.03.009.
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    • Kobashigawa, J. W., L. W. Miller, G. M. Felker, S. D. Russel, G. A. Ewald, M. Zucker, L. Goldberg, et al. “12 month report of a 3 arm multicenter comparison of Tacrolimus (TAC), MMF or TAC/Sirolimus(SRL) and steroids vs Cyclosporine microemulsion(CYA), MMF and steroids in de novo cardiac transplant recipients.” The Journal of Heart and Lung Transplantation 24, no. 2 (February 2005): S61–62. https://doi.org/10.1016/j.healun.2004.11.084.
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    • Yager, J., K. Barbour, R. LaCaille, M. Felker, A. Hernandez, S. Russell, C. Milano, E. Stone, A. Brosse, and J. A. Blumenthal. “Depressive symptoms in heart transplant recipients in an alternate list program.” The Journal of Heart and Lung Transplantation 24, no. 2 (2005): S132.
    • Felker, G Michael, Jeffrey D. Leimberger, Robert M. Califf, Michael S. Cuffe, Barry M. Massie, Kirkwood F. Adams, Mihai Gheorghiade, and Christopher M. O’Connor. “Risk stratification after hospitalization for decompensated heart failure.” J Card Fail 10, no. 6 (December 2004): 460–66. https://doi.org/10.1016/j.cardfail.2004.02.011.
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    • Hernandez, A. F., and G. M. Felker. “Using BNP levels in the assessment of dyspnea.” Journal of Respiratory Diseases 25, no. 10 (October 1, 2004): 402–3.
    • Felker, G Michael, Kirkwood F. Adams, Wendy A. Gattis, and Christopher M. O’Connor. “Anemia as a risk factor and therapeutic target in heart failure.” J Am Coll Cardiol 44, no. 5 (September 1, 2004): 959–66. https://doi.org/10.1016/j.jacc.2004.05.070.
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    • Benza, Raymond L., José A. Tallaj, G Michael Felker, K Michael Zabel, Walter Kao, Robert C. Bourge, Douglas Pearce, et al. “The impact of arrhythmias in acute heart failure.” J Card Fail 10, no. 4 (August 2004): 279–84. https://doi.org/10.1016/j.cardfail.2003.12.007.
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    • Yager, Jonathan E. E., and G Michael Felker. “Left ventricular assist devices as destination therapy for end-stage heart failure.” Am Heart J 148, no. 2 (August 2004): 252–53. https://doi.org/10.1016/j.ahj.2004.06.013.
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    • Pulerwitz, Todd C., Thomas P. Cappola, G Michael Felker, Joshua M. Hare, Kenneth L. Baughman, and Edward K. Kasper. “Mortality in primary and secondary myocarditis.” Am Heart J 147, no. 4 (April 2004): 746–50. https://doi.org/10.1016/j.ahj.2003.10.029.
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    • Joynt, Karen E., Wendy A. Gattis, Vic Hasselblad, Sergey Y. Fuzaylov, Victor L. Serebruany, Paul A. Gurbel, Laura H. Gaulden, G Michael Felker, David J. Whellan, and Christopher M. O’Connor. “Effect of angiotensin-converting enzyme inhibitors, beta blockers, statins, and aspirin on C-reactive protein levels in outpatients with heart failure.” Am J Cardiol 93, no. 6 (March 15, 2004): 783–85. https://doi.org/10.1016/j.amjcard.2003.12.010.
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    • Mark, Daniel B., and G Michael Felker. “B-type natriuretic peptide - a biomarker for all seasons?” N Engl J Med 350, no. 7 (February 12, 2004): 718–20. https://doi.org/10.1056/NEJMe038233.
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    • Felker, G Michael, Adrian F. Hernandez, Joseph G. Rogers, Stuart D. Russell, Nancy L. Reinsmoen, Paul Rosenberg, Jonathan A. Hata, Andrew J. Lodge, and Carmelo A. Milano. “Cardiac transplantation at Duke University Medical Center.” Clin Transpl, 2004, 235–41.
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    • Trichon, Benjamin H., Donald D. Glower, Linda K. Shaw, Christopher H. Cabell, Kevin J. Anstrom, G Michael Felker, and Christopher M. O’Connor. “Survival after coronary revascularization, with and without mitral valve surgery, in patients with ischemic mitral regurgitation.” Circulation 108 Suppl 1 (September 9, 2003): II103–10. https://doi.org/10.1161/01.cir.0000087656.10829.df.
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    • Felker, G Michael, Wendy A. Gattis, Jeffrey D. Leimberger, Kirkwood F. Adams, Michael S. Cuffe, Mihai Gheorghiade, and Christopher M. O’Connor. “Usefulness of anemia as a predictor of death and rehospitalization in patients with decompensated heart failure.” Am J Cardiol 92, no. 5 (September 1, 2003): 625–28. https://doi.org/10.1016/s0002-9149(03)00740-9.
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    • Felker, G Michael, Raymond L. Benza, A Bleakley Chandler, Jeffrey D. Leimberger, Michael S. Cuffe, Robert M. Califf, Mihai Gheorghiade, Christopher M. O’Connor, and Christopher M. OPTIME-CHF Investigators. “Heart failure etiology and response to milrinone in decompensated heart failure: results from the OPTIME-CHF study.” J Am Coll Cardiol 41, no. 6 (March 19, 2003): 997–1003. https://doi.org/10.1016/s0735-1097(02)02968-6.
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    • Trichon, Benjamin H., G Michael Felker, Linda K. Shaw, Christopher H. Cabell, and Christopher M. O’Connor. “Relation of frequency and severity of mitral regurgitation to survival among patients with left ventricular systolic dysfunction and heart failure.” Am J Cardiol 91, no. 5 (March 1, 2003): 538–43. https://doi.org/10.1016/s0002-9149(02)03301-5.
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    • Felker, G Michael, Kirkwood F. Adams, Marvin A. Konstam, Christopher M. O’Connor, and Mihai Gheorghiade. “The problem of decompensated heart failure: nomenclature, classification, and risk stratification.” Am Heart J 145, no. 2 Suppl (February 2003): S18–25. https://doi.org/10.1067/mhj.2003.150.
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    • Felker, G Michael, and Christopher M. O’connor. “A bridge for the 21st century in heart transplantation?” Am Heart J 145, no. 2 (February 2003): 198–99. https://doi.org/10.1067/mhj.2003.51.
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    • Gattis, Wendy A., Christopher M. O’Connor, Jeffrey D. Leimberger, G Michael Felker, Kirkwood F. Adams, and Mihai Gheorghiade. “Clinical outcomes in patients on beta-blocker therapy admitted with worsening chronic heart failure.” Am J Cardiol 91, no. 2 (January 15, 2003): 169–74. https://doi.org/10.1016/s0002-9149(02)03104-1.
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    • Felker, G Michael, Linda K. Shaw, and Christopher M. O’Connor. “Reply.” Journal of the American College of Cardiology 40, no. 1 (July 2002): 206–206. https://doi.org/10.1016/s0735-1097(02)01919-8.
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    • Cappola, Thomas P., G Michael Felker, WH Linda Kao, Joshua M. Hare, Kenneth L. Baughman, and Edward K. Kasper. “Pulmonary hypertension and risk of death in cardiomyopathy: patients with myocarditis are at higher risk.” Circulation 105, no. 14 (April 9, 2002): 1663–68. https://doi.org/10.1161/01.cir.0000013771.30198.82.
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    • Trichon, B. H., G. M. Felker, L. K. Shaw, C. H. Cabell, and C. M. O’Connor. “Mitral regurgitation is an independent risk factor for mortality in patients with heart failure and left ventricular systolic dysfunction.” Journal of the American College of Cardiology 39, no. 5 (March 6, 2002): 194A-194A.
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    • Felker, G Michael, Linda K. Shaw, and Christopher M. O’Connor. “A standardized definition of ischemic cardiomyopathy for use in clinical research.” J Am Coll Cardiol 39, no. 2 (January 16, 2002): 210–18. https://doi.org/10.1016/s0735-1097(01)01738-7.
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    • Felker, G. M., and C. M. O’connor. “Between Scylla and Charybdis: The choice of inotropic agent for decompensated heart failure.” Am Heart J 142, no. 6 (December 2001): 932–33. https://doi.org/10.1067/mhj.2001.119611.
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    • Benza, R. L., G. M. Felker, K. M. Zabel, W. Kao, R. J. Hilkert, D. Pearce, S. Borzak, J. D. Leimberger, and M. Gheorghiade. “Arrhythmias in heart failure exacerbations: The OPTIME-CHF study.” Circulation 104, no. 17 (October 23, 2001): 525–525.
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    • Felker, G. M., J. D. Leimberger, M. S. Cuffe, and M. Gheorghiade. “The combination of digoxin and milrinone therapy is not associated with an increased risk of adverse outcomes in patients hospitalized for heart failure: Results from the OPTIME-CHF study.” Circulation 104, no. 17 (October 23, 2001): 571–72.
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    • Felker, G. M., J. D. Leimberger, R. M. Califf, M. S. Cuffe, M. Gheorghiade, and C. M. O’Connor. “A predictive model for the risk of death or rehospitalization after admission for decompensated heart failure: Results from the OPTIME-CHF study.” Circulation 104, no. 17 (October 23, 2001): 689–689.
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    • Felker, G. M., R. L. Benza, A. B. Chandler, L. Berger, S. M. Teague, J. D. Leimberger, K. D. Lucas, M. S. Cuffe, M. Gheorghiade, and C. M. O’Connor. “Heart failure etiology and response to intravenous milrinone decompensated heart failure: The OPTIME-CHF study.” Circulation 104, no. 17 (October 23, 2001): 421–421.
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    • Felker, G. M., and C. M. O’Connor. “Inotropic therapy for heart failure: an evidence-based approach.” Am Heart J 142, no. 3 (September 2001): 393–401. https://doi.org/10.1067/mhj.2001.117606.
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    • Bahit, Maria Cecilia, Christopher H. Cabell, Christopher K. Dyke, G Michael Felker, Padma Kaul, Darren K. McGuire, J Conor O’Shea, Donal Reddan, and Mark East. “Highlights from the American College of Cardiology Forty-Ninth Annual Scientific Sessions: March 18 to 21, 2001.” American Heart Journal 142, no. 2 (August 2001): 363–74. https://doi.org/10.1067/mhj.2001.117061.
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    • Felker, G. M., and C. M. O’Connor. “Rational use of inotropic therapy in heart failure.” Curr Cardiol Rep 3, no. 2 (March 2001): 108–13. https://doi.org/10.1007/s11886-001-0035-8.
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    • Felker, G. M., L. K. Shaw, and C. M. O’Connor. “The extent of coronary artery disease and long-term survival in patients with symptomatic left ventricular systolic dysfunction.” Journal of the American College of Cardiology 37, no. 2 (February 1, 2001): 177A-177A.
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    • Bahit, M. C., C. H. Cabell, C. K. Dyke, G. M. Felker, P. Kaul, D. K. McGuire, J. C. O’Shea, D. Reddan, and M. East. “Highlights from the American college of cardiology 50th annual scientific sessions: March 18 to 21, 2001 (vol 142, pg 363, 2001).” American Heart Journal 142, no. 4 (2001): 678–678.
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    • Felker, G. M., C. J. Jaeger, E. Klodas, D. R. Thiemann, J. M. Hare, R. H. Hruban, E. K. Kasper, and K. L. Baughman. “Myocarditis and long-term survival in peripartum cardiomyopathy.” Am Heart J 140, no. 5 (November 2000): 785–91. https://doi.org/10.1067/mhj.2000.110091.
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    • Felker, G. M., J. P. Boehmer, R. H. Hruban, G. M. Hutchins, E. K. Kasper, K. L. Baughman, and J. M. Hare. “Echocardiographic findings in fulminant and acute myocarditis.” J Am Coll Cardiol 36, no. 1 (July 2000): 227–32. https://doi.org/10.1016/s0735-1097(00)00690-2.
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    • Felker, G. M., R. E. Thompson, J. M. Hare, R. H. Hruban, D. E. Clemetson, D. L. Howard, K. L. Baughman, and E. K. Kasper. “Underlying causes and long-term survival in patients with initially unexplained cardiomyopathy.” N Engl J Med 342, no. 15 (April 13, 2000): 1077–84. https://doi.org/10.1056/NEJM200004133421502.
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    • Camobreco, V., R. Ham, M. Barlaz, E. Repa, M. Felker, C. Rousseau, and J. Rathle. “Life-cycle inventory of a modern municipal solid waste landfill.” Waste Management &Amp; Research: The Journal for a Sustainable Circular Economy 17, no. 6 (December 1999): 394–408. https://doi.org/10.1177/0734242x9901700602.
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    • Felker, G. M., W. Hu, J. M. Hare, R. H. Hruban, K. L. Baughman, and E. K. Kasper. “The spectrum of dilated cardiomyopathy. The Johns Hopkins experience with 1,278 patients.” Medicine (Baltimore) 78, no. 4 (July 1999): 270–83. https://doi.org/10.1097/00005792-199907000-00005.
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    • Felker, G. M., H. S. Friedman, M. E. Dolan, R. C. Moschel, and C. Schold. “Treatment of subcutaneous and intracranial brain tumor xenografts with O6-benzylguanine and 1,3-bis(2-chloroethyl)-1-nitrosourea.” Cancer Chemother Pharmacol 32, no. 6 (1993): 471–76. https://doi.org/10.1007/BF00685892.
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    • Friedman, H. S., M. E. Dolan, R. C. Moschel, A. E. Pegg, G. M. Felker, J. Rich, D. D. Bigner, and S. C. Schold. “Enhancement of nitrosourea activity in medulloblastoma and glioblastoma multiforme.” J Natl Cancer Inst 84, no. 24 (December 16, 1992): 1926–31. https://doi.org/10.1093/jnci/84.24.1926.
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    • Wang, Teresa, Emily C. O’Brien, Joseph G. Rogers, Daniel L. Jacoby, Michael E. Chen, Jeffrey M. Testani, Dawn E. Bowles, et al. “Plasma Levels of MicroRNA-155 Are Upregulated with Long-Term Left Ventricular Assist Device Support.” Asaio J 63, no. 5 (n.d.): 536–41. https://doi.org/10.1097/MAT.0000000000000564.
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  • Book Sections

    • Wong, Y. W., and G. M. Felker. “Etiology and overview of heart failure.” In Advances in Heart Failure Management, 7–17, 2012. https://doi.org/10.2217/EBO.11.229.
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    • Felker, G. M., and J. R. Teerlink. “Clinical Trial Design in Heart Failure.” In Heart Failure: A Companion to Braunwald’s Heart Disease Expert Consult, 570–93, 2010. https://doi.org/10.1016/B978-1-4160-5895-3.10039-7.
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    • Holley, C. L., and G. A. Ewald. “Acute decompensated heart failure.” In The Washington Manual of Critical Care, edited by M. H. Kollef, T. J. Bedient, T. J. Isakow W, and C. A. Witt. Lippincott Williams & Wilkins, 2008.
    • Markham, D. W., and G. M. Felker. “Vasodilators in the management of heart failure.” In Treatment of Advanced Heart Disease, 99–112, 2006.
    • Cotter, G., W. G. Stough, G. M. Felker, E. J. Velazquez, A. F. Hernandez, J. G. Rogers, M. Gheorghiade, K. F. Adams, and C. M. O’Connor. “Acute heart failure: Nomenclature, pathophysiology, and outcome measures.” In Management of Acute Decompensated Heart Failure, 19–38, 2005. https://doi.org/10.4324/9780203421345-7.
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    • Felker, G. M., A. F. Hernandez, and A. Maisel. “Biologic markers in acute heart failure.” In Management of Acute Decompensated Heart Failure, 151–64, 2005. https://doi.org/10.4324/9780203421345-16.
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    • Felker, G. M., and K. F. Adams. “Anemia in acute and chronic heart failure.” In Management of Acute Decompensated Heart Failure, 273–84, 2005. https://doi.org/10.4324/9780203421345-25.
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    • Felker, G. M., and M. Gheorghiade. “Inotropes and other new therapies for acute heart failure.” In Management of Acute Decompensated Heart Failure, 339–48, 2005. https://doi.org/10.4324/9780203421345-30.
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  • Other Articles

    • Patel, C. B., M. L. MacKinnon, A. D. Smith, G. M. Felker, D. Vikraman-Sushama, D. L. Sudan, P. B. Rosenberg, A. F. Hernandez, C. A. Milano, and J. G. Rogers. “Successful organ donation after long-term circulatory support with nonpulsatile mechanical support.” Am J Transplant, July 2012. https://doi.org/10.1111/j.1600-6143.2012.04105.x.
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    • Gottfredsson, M., G. M. Cox, and J. R. Perfect. “Reply.” J Infect Dis, February 2000. https://doi.org/10.1086/315295.
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  • Conference Papers

    • Abboud, A., G. M. Felker, J. Butler, A. S. Maisel, I. L. Pina, S. P. Murphy, M. F. Prescott, et al. “Left-heart reverse remodeling patterns following treatment with sacubitril/valsartan.” In European Journal of Heart Failure, 24:96–96, 2022.
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    • Hebl, Virginia B., Susanna R. Stevens, Hiroyuki Takahama, Bradley A. Bart, Horng H. Chen, G. M. Felker, Steven R. Goldsmith, and Margaret M. Redfield. “ADHERE Risk Levels Predict 60-day Death and Re-hospitalization in Clinical Trial Patients with Acute Decompensated Heart Failure.” In Circulation, Vol. 130, 2014.
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    • Rajagopal, Keshava, Mani A. Daneshmand, Gary M. Felker, Adrian F. Hernandez, Joseph G. Rogers, Andrew J. Lodge, and Carmelo A. Milano. “Right Ventricular Dysfunction in Recipients of Destination Therapy Left Ventricular Assist Devices versus Marginal-Donor Cardiac Allografts.” In Circulation, 120:S798–S798. LIPPINCOTT WILLIAMS & WILKINS, 2009.
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    • Metra, Marco, John R. Teerlink, Adriaan A. Voors, G Michael Felker, Elaine Unemori, Beth Weatherley, Sam L. Teichman, and Gad Cotter. “How Should Dyspnea Be Measured in Acute Heart Failure?: A Comparison of Visual Analog and Likert Scales in an International Clinical Trial.” In Journal of the American College of Cardiology, 53:A160–A160, 2009.
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    • Parker, J. D., A. D. Michaels, D. A. Kass, A. A. Wolff, G. M. Felker, and F. I. Malik. “Rationale and Design for a Phase II Study Evaluating the Effect of the Cardiac Myosin Activator, CK-1827452, on Cardiac Function, Hemodynamics, and Myocardial Oxygen Consumption in Patients with Heart Failure.” In Journal of Cardiac Failure, 14:S79–S79. Elsevier BV, 2008. https://doi.org/10.1016/j.cardfail.2008.06.438.
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    • Allen, Larry A., Jonathan E. Yager, James A. Tulsky, Margaret T. Bowers, Gwen C. Dodson, Wayne C. Levy, Michele Jonsson Funk, Christopher M. O’Connor, and G Michael Felker. “Discordance between patient-predicted and model-predicted life expectancy among outpatient heart failure patients.” In Journal of the American College of Cardiology, 51:A269–A269. ELSEVIER SCIENCE INC, 2008.
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    • Chiong, J. R., J. K. Ghali, S. H. Dunlap, D. J. Lenihan, M. R. Mehra, R. M. Oren, J. H. Patterson, J. Butler, G. M. Felker, and KF Jr Adams. “Troponin T not human fatty acid binding protein predicts important clinical outcomes in chronic heart failure.” In European Heart Journal, 29:179–179, 2008.
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    • Allen, Larry A., G Michael Felker, Stuart J. Pocock, John J. V. McMurray, Marc A. Pfeffer, Karl Swedberg, Duolao Wang, Salim Yusuf, Eric L. Michelson, and Christopher B. Granger. “Liver function test abnormalities and outcome in patients with chronic heart failure: Data from the candesartan in heart failure assessment of reduction in mortality and morbidity (CHARM) program.” In Journal of the American College of Cardiology, 49:44A-44A. ELSEVIER SCIENCE INC, 2007.
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    • Allen, Larry A., G Michael Felker, Stuart J. Pocock, Linda K. Shaw, John J. V. McMurray, Marc A. Pfeffer, Karl Swedberg, Salim Yusuf, Eric L. Michelson, and Christopher B. Granger. “Red cell distribution width as a novel prognostic marker in heart failure: Data from the CHARM program and the duke databank.” In Journal of the American College of Cardiology, 49:88A-88A. ELSEVIER SCIENCE INC, 2007.
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    • Lima, B., K. Rajagopal, R. G. Mesis, R. P. Petersen, B. Soule, G. M. Felker, J. G. Rogers, A. J. Lodge, and C. A. Milano. “434: Infections in alternate versus standard list heart transplant patients: Implications for immunosuppression.” In The Journal of Heart and Lung Transplantation, 26:S216–17. Elsevier BV, 2007. https://doi.org/10.1016/j.healun.2006.11.456.
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    • Cotts, William G., Stephanie H. Dunlap, Douglas D. Schocken, Carla A. Dupree, Ileana L. Pina, Jun R. Chiong, G Michael Felker, et al. “Decreasing Hemoglobin during Follow-Up Is Associated with Declining Quality of Life in Unselected Outpatients with Heart Failure: Results from the Study of Anemia in a Heart Failure Population (STAMINA-HFP) Registry.” In Journal of Cardiac Failure, 12:S98–S98. Elsevier BV, 2006. https://doi.org/10.1016/j.cardfail.2006.06.335.
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    • Milo-Cotter, Olga, Kirkwood F. Adams, Michael Felker, Beth Weatherly, Nir Uriel, Edo Kaluski, Zvi Vered, Christopher M. O’Connor, and Gad Cotter. “Acute Heart Failure Associated with High Admission Blood Pressure – A Very Common, yet Distinct Vascular Disorder?” In Journal of Cardiac Failure, 12:S78–S78. Elsevier BV, 2006. https://doi.org/10.1016/j.cardfail.2006.06.268.
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    • Milo-Cotter, Olga, Nir Uriel, Michael Felker, Beth Weatherly, Edo Kalusi, Zvi Vered, Christopher M. O’Connor, and Gad Cotter. “Rapid (2 Minutes) Clinical Assessment of Respiratory Failure (Oxygen Saturation) and Circulatory Failure (Systolic Blood Pressure) – An Easy and Acurate Way To Risk Stratify Patients with Acute Heart Failure at Admission?” In Journal of Cardiac Failure, 12:S74–S74. Elsevier BV, 2006. https://doi.org/10.1016/j.cardfail.2006.06.250.
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    • Rogers, Joseph G., G Michael Felker, O. H. Frazier, and Eric A. Rose. “Clinical Characteristics and Outcomes of Patients Supported with Left Ventricular Assist Devices: Are Bridge-to-Transplant and Destination Therapy Populations Different?” In Journal of Cardiac Failure, 12:S53–S53. Elsevier BV, 2006. https://doi.org/10.1016/j.cardfail.2006.06.186.
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    • Milo-Cotter, O., N. Uriel, G. M. Felker, E. J. Velazquez, B. Weatherly, J. R. Rogers, A. Hernandez, et al. “Acute heart failure asociated with atrial fibrillation: A distinct disorder and not just a fast pulse rate?” In Journal of the American College of Cardiology, 47:86A-86A. ELSEVIER SCIENCE INC, 2006.
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    • Kittleson, M. M., A. Skye, G. M. Felker, P. B. Rosenberg, J. Warren, C. A. Milano, and S. D. Russell. “241.” In The Journal of Heart and Lung Transplantation, 25:S127–S127. Elsevier BV, 2006. https://doi.org/10.1016/j.healun.2005.11.251.
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    • Lima, B., K. Rajagopal, R. P. Petersen, A. S. Shah, B. Soule, G. M. Felker, J. G. Rogers, A. J. Lodge, and C. A. Milano. “Marginal cardiac allografts do not display increased incidence of primary graft dysfunction in alternate list heart transplant recipients.” In Circulation, 112:U393–U393. LIPPINCOTT WILLIAMS & WILKINS, 2005.
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    • Felker, G. M., L. E. Wagoner, M. R. Mehra, J. K. Ghali, R. M. Oren, S. H. Dunlap, J. Butler, et al. “Evolution of hemoglobin concentration in outpatients with heart failure: Results from the study of anemia in a heart failure population (STAMINA-HFP) registry.” In Journal of Cardiac Failure, 11:S176–S176. CHURCHILL LIVINGSTONE INC MEDICAL PUBLISHERS, 2005.
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    • Pina, I., J. Chiong, K. Hebert, S. Robbins, D. Schocken, G. M. Felker, W. Cotts, et al. “Anemia is an important independent risk factor for morbidity and mortality in elderly patients with heart failure: Results from STAMINA-HFP.” In Circulation, 111:E340–E340. LIPPINCOTT WILLIAMS & WILKINS, 2005.
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    • Russell, S. D., G. M. Felker, L. Blue, M. B. Higginbotham, and C. A. Milano. “Mortality associated with use of hepatitis C positive donors in alternate list heart transplantation.” In The Journal of Heart and Lung Transplantation, 24:S78–S78. Elsevier BV, 2005. https://doi.org/10.1016/j.healun.2004.11.133.
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    • Adams, K. F., M. R. Mehra, J. R. Chiong, L. E. Wagoner, J. H. Patterson, W. A. Gattis, G. M. Felker, et al. “Lower hemoglobin is associated with reduced survival in unselected outpatients with heart failure: Results from the study of anemia in a heart failure population (STAMINA-HFP) registry.” In Circulation, 110:751–751. LIPPINCOTT WILLIAMS & WILKINS, 2004.
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    • Dunlap, Stephanie H., Ileana L. Pina, William G. Cotts, Lynne E. Wagoner, Ron M. Oren, Wendy A. Gattis, Mandeep R. Mehra, et al. “Lower Hemoglobin Is Associated with Persistently Reduced Quality of Life in Unselected Patients with Heart Failure: Results from the Study of Anemia in a Heart Failure Population (STAMINA-HFP) Registry.” In Journal of Cardiac Failure, 10:S102–S102. Elsevier BV, 2004. https://doi.org/10.1016/j.cardfail.2004.06.310.
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    • Felker, G Michael, Linda K. Shaw, Wendy A. Gattis, and Christopher M. O’Connor. “Anemia, coronary artery disease severity, and survival in chronic heart failure.” In Journal of Cardiac Failure, 10:S105–S105. Elsevier BV, 2004. https://doi.org/10.1016/j.cardfail.2004.06.325.
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    • Felker, G Michael, Linda K. Shaw, Wendy A. Gattis, and Christopher M. O’Connor. “Anemia and survival in patients with heart failure and preserved systolic function.” In Journal of Cardiac Failure, 10:S96–S96. Elsevier BV, 2004. https://doi.org/10.1016/j.cardfail.2004.06.290.
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    • Hata, J. A., J. R. Keys, B. C. Blaxall, J. A. Petrofski, S. I. Hanish, M. L. Williams, G. M. Felker, C. A. Milano, and W. J. Koch. “Differential expression of G-protein coupled receptor kinases after mechanical unloading in the failing human heart.” In Circulation, 108:15–16. LIPPINCOTT WILLIAMS & WILKINS, 2003.
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    • Trichon, B. H., D. D. Glower, L. K. Shaw, G. M. Felker, C. H. Cabell, and C. M. O’Connor. “Coronary revascularization, with and without mitral valve repair/replacement, is associated with improved survival in patients with ischemic mitral regurgitation.” In Circulation, 106:504–504. LIPPINCOTT WILLIAMS & WILKINS, 2002.
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    • Kwee, L. C., W. Hunter, R. W. McGarrah, J. P. Kelly, D. M. Craig, P. Shipkova, M. Reily, et al. “Global Metabolomic Profiling in Heart Failure With Preserved Ejection Fraction Identifies Markers of Myocardial Dysfunction,” n.d.

  • Preprints

    • Sinha, Shashank S., Mitchell A. Psotka, Mona Fiuzat, Scott D. Barnett, Martina Bruckmann, Javed Butler, Mary M. DeSouza, et al. “Barriers to Clinical Trial Efficiency and Patient Access: The Heart Failure Collaboratory Industry Survey.” Cold Spring Harbor Laboratory, June 29, 2020. https://doi.org/10.1101/2020.06.24.20124917.
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