Skip to main content

Michael T Forrester

Medical Instructor in the Department of Medicine
Medicine, Pulmonary, Allergy, and Critical Care Medicine
303 Research Drive, Sands 455,, Durham, NC 27710

Scholarly Works - Preprints


Topology-Driven Discovery of Transmembrane Protein S-Palmitoylation.

Preprint · September 8, 2024 Protein S-palmitoylation is a reversible lipophilic posttranslational modification regulating a diverse number of signaling pathways. Within transmembrane proteins (TMPs), S-palmitoylation is implicated in conditions from inflammatory disorders to respirat ... Full text Link to item Cite

Analysis of Protein Cysteine Acylation Using a Modified Suspension Trap (Acyl-Trap).

Preprint · June 29, 2024 Proteins undergo reversible S-acylation via a thioester linkage in vivo. S-palmitoylation, modification by C16:0 fatty acid, is a common S-acylation that mediates critical protein-membrane and protein-protein interactions. The most widely used S-acylation ... Full text Link to item Cite