https://orcid.org/0000-0002-8715-5210
Overview
With a clinical background in neuroanesthesia and neurointensive care, I have a special interest in translational research in intracerebral hemorrhage and traumatic brain injury. I am fortunate to be part of a unique team of highly motivated and productive individuals who allow me to propel ideas from bench to bedside and the ability to reverse translate ideas from the bedside back to the bench.
Current Duke Appointments & Affiliations
Professor of Anesthesiology
·
2023 - Present
Anesthesiology, Neuroanesthesia,
Anesthesiology
Assistant Vice Chancellor for Duke-NUS Research
·
2021 - Present
Anesthesiology,
Clinical Science Departments
Professor in Neurology
·
2023 - Present
Neurology,
Clinical Science Departments
Professor in Neurosurgery
·
2023 - Present
Neurosurgery,
Neurosurgery
Member in the Duke Clinical Research Institute
·
2018 - Present
Duke Clinical Research Institute,
Institutes and Centers
Recent Scholarly Works
Hematoma Interleukin-1 Receptor Antagonist Concentrations Predict Long-Term Outcome in Acute Human Intracerebral Hemorrhage.
Journal article Ann Neurol · August 2026 OBJECTIVES: The interleukin (IL)-1, IL-6, and C-reactive protein (CRP) pathway is central to the immune response after intracerebral hemorrhage (ICH). We tested for associations between hematoma and plasma cytokine concentrations and patient outcomes in Mi ... Full text Link to item CitePatient-and Caregiver-Centered Outcomes in Survivors of Severe Stroke with Respiratory Failure at 6 Months: A Substudy of the SETPOINT2 Trial.
Journal article Neurocrit Care · July 20, 2026 BACKGROUND/OBJECTIVE: The multicenter trial SETPOINT2 comparing early versus delayed tracheostomy in severe stroke was conducted in Germany and the USA. A pre-specified aim was to assess 6-month patient- and caregiver-reported outcomes to better inform cli ... Full text Link to item CiteAssociation of blood pressure variability with clinical and biomarker outcomes in moderate to severe TBI: A TRACK-TBI study.
Journal article J Clin Neurosci · July 2026 INTRODUCTION: Traumatic brain injury (TBI) represents a significant global health burden and often results in functional impairment. Blood pressure variability (BPV), a surrogate marker of autonomic dysfunction, has been shown to influence outcomes in pati ... Full text Link to item CiteRecent Grants
Mid-Atlantic praGmatic NETwork for Involving many different, scientifically representative populations in Clinical trials in emergency care (MAGNETIC)
ResearchCo-Principal Investigator · Awarded by National Institute of Neurological Disorders and Stroke · 2023 - 2028CN105 improves surrogate and functional outcomes after intracerebral hemorrhage (Subaward to AegisCN)
ResearchPrincipal Investigator · Awarded by AegisCN LLC · 2024 - 2026Brain Oxygen Optimization in Severe Traumatic Brain Injury (BOOST-3)
Clinical TrialPrincipal Investigator · Awarded by University of Michigan · 2019 - 2025View All Grants
Education
Louisiana State University ·
1999
M.D.