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Michael Barry Kastan

William and Jane Shingleton Distinguished Professor of Pharmacology and Cancer Biology
Pharmacology & Cancer Biology
MSRB3, 3 Genome Court, Box 103057, Durham, NC 27710
MSRB3, 3 Genome Court, Box 103057, Durham, NC 27710

Scholarly Works - Book sections


DNA Damage Response Pathways and Cancer

Book section · January 1, 2019 DNA repair and the cellular response to DNA damage are critical for maintaining genomic stability. Defects in DNA repair or the response to DNA damage encountered from endogenous or external sources results in an increased rate of genetic mutations, often ... Full text Cite

DNA Damage Response Pathways and Cancer

Book section · October 22, 2013 Full text Cite

20 years of DNA damage signaling to p53

Book section · January 1, 2005 The short history of p53 contains an overwhelming number of facts and hypotheses, presenting the challenge of integrating diverse and sometimes mutually exclusive ideas into a coherent picture. It is important to make a distinction between p53 tumor suppre ... Full text Cite