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Carmelo Alessio Milano

Joseph W. and Dorothy W. Beard Distinguished Professor of Experimental Surgery
Surgery, Cardiovascular and Thoracic Surgery
Box 3043 Med Ctr, Durham, NC
4532A Hosp South - Blue Zone, Durham, NC 27710

Scholarly Works - Conferences


2025 American Association for Thoracic Surgery (AATS) Expert Consensus Document: Surgical management of acute myocardial infarction and associated complications.

Conference J Thorac Cardiovasc Surg · November 2025 BACKGROUND: Complications of acute myocardial infarction (AMI) can result in significant morbidity and mortality. This document reports the findings and recommendations of a multidisciplinary group of experts on the management of patients with complication ... Full text Link to item Cite

A porcine model of acute rejection for cardiac transplantation

Conference Frontiers in Cardiovascular Medicine · January 1, 2025 Ex vivo machine perfusion has been growing in utility for preserving donor organs prior to transplantation. This modality has tremendous potential for bioengineering and conditioning organs prior to transplantation using small molecule or advanced therapeu ... Full text Cite

Heart transplant survival and the use of donors with intracranial bleeding: United Network for Organ Sharing Registry propensity-score matched analysis.

Conference JTCVS Open · December 2024 OBJECTIVE: The transplantation of hearts from donors who experienced intracranial bleeding (ICB) has been associated with inferior long-term survival in both single-center analyses and, more recently, with the United Network for Ogan Sharing Registry. The ... Full text Link to item Cite

Durability of porcine and pericardial prostheses in tricuspid valve replacement.

Conference JTCVS Open · October 2024 OBJECTIVE: Biologic valves dominate tricuspid valve replacement, yet data on different valve types are lacking. We compare the survival and durability of porcine and pericardial tricuspid prostheses. METHODS: A retrospective review of consecutive patients ... Full text Link to item Cite

Metabolomic profiling during ex situ normothermic perfusion before heart transplantation defines patterns of substrate utilization and correlates with markers of allograft injury.

Conference J Heart Lung Transplant · May 2024 BACKGROUND: Cardiac metabolism is altered in heart failure and ischemia-reperfusion injury states. We hypothesized that metabolomic profiling during ex situ normothermic perfusion before heart transplantation (HT) would lend insight into myocardial substra ... Full text Link to item Cite

Infarct exclusion repair of postmyocardial infarction ventricular septal rupture with a hybrid patch and septal occluder device compared with patch only.

Conference JTCVS Tech · December 2023 OBJECTIVE: We developed a hybrid technique for repairing post-myocardial infarction (MI) ventricular septal defect (VSD) that combines infarct exclusion with patch and a nitinol-mesh septal occluder device (SOD) to provide a scaffold to support the damaged ... Full text Link to item Cite

Transplanting Thoracic COVID-19 Positive Donors: Overcoming the Pandemic

Conference JOURNAL OF HEART AND LUNG TRANSPLANTATION · April 2022 Link to item Cite

Trends in Substance Use in Patients Requiring Advanced Heart Failure Therapies

Conference JOURNAL OF HEART AND LUNG TRANSPLANTATION · April 2022 Link to item Cite

Inhaled Selective Pulmonary Vasodilators for Advanced Heart Failure Therapies

Conference JOURNAL OF HEART AND LUNG TRANSPLANTATION · April 2021 Link to item Cite

Successful Gene Delivery to Cardiac Allograft with Adeno-Associated Viral Vector Using Ex Vivo Storage Perfusion Platform

Conference The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · April 1, 2020 PURPOSE: Cardiac gene therapy remains limited by inefficient transgene delivery with currently available methods (intravenous infusion, transcatheter coronary artery infusion, direct myocardial injection). We previously demonstrated in a porcine heterotopi ... Full text Cite

Impact of Tricuspid Valve Repair for Moderate Tricuspid Regurgitation at the Time of Left Ventricular Assist Device Implantation on the Occurrence of Right Heart Failure

Conference The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · April 1, 2020 PURPOSE: Significant tricuspid regurgitation (TR) in patients undergoing durable left ventricular assist device (LVAD) implantation has been associated with increased incidence of right heart failure (RHF). There is great surgical practice variability rela ... Full text Cite

EUROMACS-RHF Risk Score and 3D Echocardiography as Predictors of Right Heart Failure after Left Ventricular Assist Device Implantation

Conference The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · April 1, 2020 PURPOSE: Right heart failure (RHF) after LVAD implantation is associated with significant morbidity and mortality. Recently, the EUROMACS-RHF risk score was developed to predict postoperative RHF in this setting. In a single-center analysis, we assessed th ... Full text Cite

Pre-Formed Donor-Specific Antibodies Impact Long Term Survival of Heart Transplants

Conference The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · April 1, 2020 PURPOSE: We previously reported that heart transplant (HTx) recipients with pre-formed, anti-HLA antibodies at low titer had one-year survival that was comparable to patients without any anti-HLA antibodies. As a result, we defined unacceptable HLA antigen ... Full text Cite

Hepatitis and Thoracic Transplantation - No More Virus Non-Grata

Conference The Journal of Heart and Lung Transplantation · April 2019 Full text Cite

Blood Pressure Management Ameliorates the Severity of Neurological Events

Conference The Journal of Heart and Lung Transplantation · April 2018 Full text Cite

Risk Assessment and Comparative Effectiveness of Left Ventricular Assist Device and Medical Management in Ambulatory Heart Failure Patients: The ROADMAP Study 2-Year Results.

Conference JACC Heart Fail · July 2017 OBJECTIVES: The authors sought to provide the pre-specified primary endpoint of the ROADMAP (Risk Assessment and Comparative Effectiveness of Left Ventricular Assist Device and Medical Management in Ambulatory Heart Failure Patients) trial at 2 years. BACK ... Full text Link to item Cite

Assessment of cardiac allograft systolic function by global longitudinal strain: From donor to recipient.

Conference Clin Transplant · May 2017 BACKGROUND: Cardiac allografts are routinely evaluated by left ventricular ejection fraction (LVEF) before and after transplantation. However, myocardial deformation analyses with LV global longitudinal strain (GLS) are more sensitive for detecting impaire ... Full text Link to item Cite

Mycobacterium Abscessus Infection in Patients with Ventricular Assist Devices

Conference JOURNAL OF HEART AND LUNG TRANSPLANTATION · April 1, 2017 Link to item Cite

Invasive Mycobacterium abscessus Infection in Heart Transplant Recipients

Conference JOURNAL OF HEART AND LUNG TRANSPLANTATION · April 1, 2017 Link to item Cite

Temporal Changes in Adverse Events in the ENDURANCE Trial

Conference The Journal of Heart and Lung Transplantation · April 2016 Full text Cite

Implications of Amiodarone Use Before Heart Transplantation

Conference The Journal of Heart and Lung Transplantation · April 2016 Full text Cite

Update on Post-Approval INTERMACs Registry of the HVAD System in Commercial Use

Conference The Journal of Heart and Lung Transplantation · April 2015 Full text Cite

Central venous pressure after coronary artery bypass surgery: does it predict postoperative mortality or renal failure?

Conference J Crit Care · December 2014 OBJECTIVE: Although hemodynamic monitoring is often performed after coronary artery bypass grafting (CABG), the role of monitoring postoperative central venous pressure (CVP) measurement as a predictor of clinical outcomes is unknown. As such, this study t ... Full text Link to item Cite

Efficacy and durability of central oversewing for treatment of aortic insufficiency in patients with continuous-flow left ventricular assist devices.

Conference J Heart Lung Transplant · September 2014 BACKGROUND: Aortic insufficiency (AI) in patients supported with continuous-flow left ventricular assist devices (CF-LVAD) results in regurgitant volume returning from the aorta to the left ventricle, increased LVAD pump volume and reduced systemic cardiac ... Full text Link to item Cite

First Report of the PAS INTERMACs Registry of the HVAD in Commercial Use

Conference The Journal of Heart and Lung Transplantation · April 2014 Full text Cite

767 Impact of Left Ventricular Assist Device Implantation upon Native Aortic Valve Regurgitation

Conference The Journal of Heart and Lung Transplantation · April 2012 Full text Cite

186 Long Term Mechanical Circulatory Support: What Are the Final Options?

Conference The Journal of Heart and Lung Transplantation · April 2012 Full text Cite

42 The Importance of Low-Titer Anti-HLA Antibodies in Cardiac Transplantation

Conference The Journal of Heart and Lung Transplantation · April 2011 Full text Cite

178 Risk of Bleeding and Stroke in 700 HeartMate II LVAD Outpatients

Conference The Journal of Heart and Lung Transplantation · April 2011 Full text Cite

66: Destination Therapy: Improving Outcomes with Continuous Flow LVADs

Conference The Journal of Heart and Lung Transplantation · February 2010 Full text Cite

54: Bleeding and Thromboembloic Complications with Pulsatile Versus Non-Pulsatile LVADs

Conference The Journal of Heart and Lung Transplantation · February 2009 Full text Cite

241

Conference The Journal of Heart and Lung Transplantation · February 2006 Full text Cite

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Conference The Journal of Heart and Lung Transplantation · February 2006 Full text Cite

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Conference The Journal of Heart and Lung Transplantation · February 2006 Full text Cite

Mortality associated with use of hepatitis C positive donors in alternate list heart transplantation

Conference The Journal of Heart and Lung Transplantation · February 2005 Full text Cite

Outcomes of an alternate list strategy for heart transplantation

Conference The Journal of Heart and Lung Transplantation · February 2005 Full text Cite