Miles Berger | Scholars@Duke

Miles Berger
Associate Professor of Anesthesiology

My research team focuses on understanding the cause of postoperative cognitive dysfunction (POCD) and delirium, and whether these disorders are caused by perioperative changes in Alzheimer's disease pathways. We are also interested in whether delirium or POCD are associated with an increased long term risk of developing Alzheimer's disease. Towards these ends, we use a combination of methods including cognitive testing, CSF and blood sampling, functional neuroimaging, and rigorous biochemical assays. This work has the potential to improve long term outcomes for the more than 16 million Americans over age 60 who undergo anesthesia and surgery each year.

Current Appointments & Affiliations

Associate Professor of Anesthesiology, Anesthesiology, Neuroanesthesia, Anesthesiology 2020
Associate of the Duke Initiative for Science & Society, Duke Science & Society, Initiatives 2017
Faculty Network Member of the Duke Institute for Brain Sciences, Duke Institute for Brain Sciences, University Institutes and Centers 2017

Contact Information

201 Trent Drive, 4317 Duke South, Orange Zone, Durham, NC 27710
DUMC Box 3094, Durham, NC 27710
miles.berger@duke.edu (919) 684-8679

Background
Education, Training, & Certifications
- Internship and Residency, Anesthesiology, Duke University School of Medicine 2009 - 2013
- M.D., University of California - San Francisco 2009
- Ph.D., University of California - San Francisco 2007
Previous Appointments & Affiliations
- Assistant Professor of Anesthesiology, Anesthesiology, Neuroanesthesia, Anesthesiology 2014 - 2020
- Medical Instructor in the Department of Anesthesiology, Anesthesiology, Neuroanesthesia, Anesthesiology 2013 - 2014
Recognition
In the News
- FEB 3, 2022 Duke Health News
  
  No Link Between Cognitive Changes, Alzheimer’s Markers After Major Surgery
- FEB 12, 2021 Duke Health News
  
  Spinal Fluid of People with Alzheimer’s Risk Gene Signals Inflammation
- JUL 12, 2016 Duke Translational Medicine Institute / DukeCTSA
  
  Supplemental Grant Aids Search for Answers to Post-Anesthesia Memory Problems
Expertise
Subject Headings
Research
Selected Grants
- Low Neurophysiologic Resistance to Anesthetics as a Marker of Preclinical/Prodromal Alzheimer's Disease and Neurovascular Pathology, Delirium risk and Inattention awarded by National Institutes of Health 2022 - 2027
- CSF Proteomic Studies of APOE4 copy number-dependent effects on the Complement Pathway awarded by National Institutes of Health 2022 - 2027
- Integrated Training in Anesthesiology Research awarded by National Institutes of Health 1996 - 2026
- Behavior and Physiology in Aging awarded by National Institutes of Health 2015 - 2025
- Pathogenesis of Neuroinflammation and Neurocognitive Impairment In HIV-infected Young Adult Cannabis Users awarded by National Institutes of Health 2019 - 2025
- FAER GEMSSTAR Supplement (rolling deadline) awarded by Foundation for Anesthesia Education and Research 2023 - 2025
- Duke Creating ADRD Researchers for the Next Generation - Stimulating Access to Research in Residency Program (CARiNG-StARR)" awarded by National Institutes of Health 2020 - 2024
- The Role of the Aging Brain-Heart-Immune Axis in Postoperative Delirium awarded by National Institutes of Health 2022 - 2024
- Neuroinflammation and Cognitive Outcomes after Spinal versus General Anesthesia in Spine Surgery awarded by AO North America 2023 - 2024
- The Association of Blood-brain Barrier Breakdown with Sleep Apnea and Postoperative Delirium awarded by Foundation for Anesthesia Education and Research 2021 - 2023
- Physical Resiliencies: Indicators and Mechanisms in the Elderly Collaborative (PRIME Collaborative) awarded by National Institutes of Health 2017 - 2023
- Geroscience signaling metabolites NAD+ and beta-hydroxybutyrate modulating acute neuroinflammation in delirium awarded by Buck Institute for Research on Aging 2020 - 2023
- The Association of Blood-Brain Barrier Breakdown with Sleep Apnea and Postoperative Delirium awarded by National Institutes of Health 2021 - 2023
- Neuro-inflammation in Postoperative Cognitive Dysfunction: CSF and fMRI Studies awarded by National Institutes of Health 2017 - 2023
- A Phase II Study of an ApoE mimetic peptide to reduce Postoperative Delirium, Cognitive Dysfunction after Non-Cardiac Surgery in Older Adults awarded by Alzheimer's Drug Discovery Foundation 2018 - 2023
- Proteomic Determination of APOE4-induced Neuroinflammation in the Pathogenesis of Alzheimer's Disease awarded by Ruth K. Broad Biomedical Research Foundation 2020 - 2022
- The Role of MCP1 and monocyte activation within the Central Nervous System in Human Postoperative Cognitive Dysfunction and Delirium awarded by Society for Neuroscience in Anesthesiology and Critical Care 2016 - 2022
- A High-Performance 3T MRI for Brain Imaging awarded by National Institutes of Health 2021 - 2022
- The Association of Blood-Brain Barrier Breakdown with Sleep Apnea and Postoperative Delirium awarded by Society for Neuroscience in Anesthesiology and Critical Care 2020 - 2021
- A Systems Biology Approach to HIV-associated Neurocognitive Impairment: Role of Drug Abuse and Neuroinflammation awarded by National Institutes of Health 2016 - 2021
- The Role of Obstructive Sleep Apnea in Neuroinflammation and Postoperative Cognitive Dysfunction awarded by Foundation for Anesthesia Education and Research 2019 - 2021
- 2015 Dennis W. Jahnigen Career Development/GEMSSTAR Program awarded by American Geriatrics Society 2015 - 2020
- The Significance of Perioperative Changes in CSF tau levels in the Elderly awarded by National Institutes of Health 2015 - 2018
- The trajectory and significance of perioperative changes in AD biomarkers awarded by International Anesthesia Research Society 2014 - 2018
- Educating Anesthesia Residents to Improve Perioperative Care for the Elderly awarded by American Geriatrics Society 2015 - 2017
- Effect of Isoflurane Versus Propofol Anesthesia on Alzheimer's Disease CSF Markers awarded by Minnetronix, Inc 2014 - 2016
External Relationships
- American Society of Anesthesiologists
- Private consulting income from individual legal cases related to postoperative neurologic and cognitive function, one in florida a few years ago, one in Michigan, and one additional one. in the last year
- Society for Neuroscience in Anesthesia and Critical Care
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Lascola, Christopher D., Sarah F. Cotter, Rebecca Y. Klinger, Tiffany Bisanar, Mary Cooter Wright, Miles Berger, Gavin Martin, et al. “Blood-brain barrier permeability and cognitive dysfunction after surgery - A pilot study.” J Clin Anesth 86 (June 2023): 111059. https://doi.org/10.1016/j.jclinane.2023.111059.
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  - Browndyke, Jeffrey N., Mary C. Wright, Rosa Yang, Ayesha Syed, John Park, Ashley Hall, Katherine Martucci, et al. “Corrigendum to 'Perioperative neurocognitive and functional neuroimaging trajectories in older APOE4 carriers compared with non-carriers: secondary analysis of a prospective cohort study' (Br J Anaesth 2021; 127: 917-928).” Br J Anaesth 130, no. 5 (May 2023): 646. https://doi.org/10.1016/j.bja.2023.02.009.
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  - Sykes, David A. W., Troy Q. Tabarestani, David S. Salven, Nauman S. Chaudhry, Timothy Y. Wang, Oren N. Gottfried, Christopher I. Shaffrey, et al. “Awake spinal anesthesia facilitates spine surgery in poor surgical candidates: A case series.” Neurochirurgie 69, no. 3 (May 2023): 101444. https://doi.org/10.1016/j.neuchi.2023.101444.
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  - Meier, Jennie, Audrey Stevens, Archana Bhat, Miles Berger, and Courtney Balentine. “Outcomes of Nonoperative vs Operative Management of Acute Appendicitis in Older Adults in the US.” Jama Surg, April 5, 2023. https://doi.org/10.1001/jamasurg.2023.0284.
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  - Meier, Jennie, Audrey Stevens, Miles Berger, Konstantinos I. Makris, Athanasios Bramos, Joan Reisch, C Munro Cullum, et al. “Comparison of Postoperative Outcomes of Laparoscopic vs Open Inguinal Hernia Repair.” Jama Surg 158, no. 2 (February 1, 2023): 172–80. https://doi.org/10.1001/jamasurg.2022.6616.
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  - Murdoch, David M., Richard Barfield, Cliburn Chan, Sheri L. Towe, Ryan P. Bell, Alicia Volkheimer, Joyce Choe, et al. “Neuroimaging and immunological features of neurocognitive function related to substance use in people with HIV.” J Neurovirol 29, no. 1 (February 2023): 78–93. https://doi.org/10.1007/s13365-022-01102-2.
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  - Chen, Gang, Jing Xu, Hao Luo, Xin Luo, Sandeep K. Singh, Juan J. Ramirez, Michael L. James, et al. “Hevin/Sparcl1 drives pathological pain through spinal cord astrocyte and NMDA receptor signaling.” Jci Insight 7, no. 23 (December 8, 2022). https://doi.org/10.1172/jci.insight.161028.
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  - David-Bercholz, Jennifer, Leah Acker, Ana I. Caceres, Pau Yen Wu, Saanvi Goenka, Nathan O. Franklin, Ramona M. Rodriguiz, et al. “Conserved YKL-40 changes in mice and humans after postoperative delirium.” Brain Behav Immun Health 26 (December 2022): 100555. https://doi.org/10.1016/j.bbih.2022.100555.
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  - Devinney, Michael J., Keith W. VanDusen, Jad M. Kfouri, Pallavi Avasarala, Andrew R. Spector, Joseph P. Mathew, and Miles Berger. “The potential link between obstructive sleep apnea and postoperative neurocognitive disorders: current knowledge and possible mechanisms.” Can J Anaesth 69, no. 10 (October 2022): 1272–87. https://doi.org/10.1007/s12630-022-02302-4.
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  - Reese, Melody, Boris Dov Heifets, and Miles Berger. “Intraoperative Anesthetic Probes of Brain Health: Ketamine as a Canary in the Coal Mine?” Anesth Analg 135, no. 4 (October 1, 2022): 679–82. https://doi.org/10.1213/ANE.0000000000005965.
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  - Meier, J., A. Stevens, M. Berger, T. P. Hogan, J. Reisch, C. M. Cullum, S. C. Lee, et al. “Use of local anesthesia for inguinal hernia repair has decreased over time in the VA system.” Hernia : The Journal of Hernias and Abdominal Wall Surgery 26, no. 4 (August 2022): 1069–75. https://doi.org/10.1007/s10029-021-02532-3.
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  - Nobuhara, Chloe, Michael Devinney, and Miles Berger. “Regional vs General Anesthesia and Incidence of Postoperative Delirium in Older Patients Undergoing Hip Fracture Surgery.” Jama 327, no. 17 (May 3, 2022): 1707–8. https://doi.org/10.1001/jama.2022.3538.
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  - Berger, Miles, Jeffrey N. Browndyke, Mary Cooter Wright, Chloe Nobuhara, Melody Reese, Leah Acker, W Michael Bullock, et al. “Postoperative changes in cognition and cerebrospinal fluid neurodegenerative disease biomarkers.” Ann Clin Transl Neurol 9, no. 2 (February 2022): 155–70. https://doi.org/10.1002/acn3.51499.
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  - Berger, Miles, Mary Cooter, Alexander S. Roesler, Stacey Chunga, John Park, Jennifer L. Modliszewski, Keith W. VanDusen, et al. “Erratum to: APOE4 Copy Number-Dependent Proteomic Changes in the Cerebrospinal Fluid.” J Alzheimers Dis 90, no. 3 (2022): 1339–40. https://doi.org/10.3233/JAD-229018.
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  - Berger, Miles, Sarada S. Eleswarpu, Mary Cooter Wright, Anna M. Ray, Sarah A. Wingfield, Mitchell T. Heflin, Shahrukh Bengali, and Ankeet D. Udani. “Developing a Real-Time Electroencephalogram-Guided Anesthesia-Management Curriculum for Educating Residents: A Single-Center Randomized Controlled Trial.” Anesthesia and Analgesia 134, no. 1 (January 2022): 159–70. https://doi.org/10.1213/ane.0000000000005677.
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  - Cooter Wright, Mary, Thomas Bunning, Sarada S. Eleswarpu, Mitchell T. Heflin, Shelley R. McDonald, Sandhya Lagoo-Deenadalayan, Heather E. Whitson, Pablo Martinez-Camblor, Stacie G. Deiner, and Miles Berger. “A Processed Electroencephalogram-Based Brain Anesthetic Resistance Index Is Associated With Postoperative Delirium in Older Adults: A Dual Center Study.” Anesth Analg 134, no. 1 (January 1, 2022): 149–58. https://doi.org/10.1213/ANE.0000000000005660.
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  - Oyeyemi, Deborah M., Mary Cooter, Stacey Chung, Heather E. Whitson, Jeffrey N. Browndyke, Michael J. Devinney, Patrick J. Smith, et al. “Relationship Between Depression/Anxiety and Cognitive Function Before and 6 Weeks After Major Non-Cardiac Surgery in Older Adults.” J Geriatr Psychiatry Neurol 35, no. 1 (January 2022): 145–54. https://doi.org/10.1177/0891988720978791.
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  - Zietlow, Kahli E., Serena Wong, Mitchell T. Heflin, Shelley R. McDonald, Robert Sickeler, Michael Devinney, Jeanna Blitz, Sandhya Lagoo-Deenadayalan, and Miles Berger. “Geriatric Preoperative Optimization: A Review.” Am J Med 135, no. 1 (January 2022): 39–48. https://doi.org/10.1016/j.amjmed.2021.07.028.
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  - Browndyke, Jeffrey N., Mary C. Wright, Rosa Yang, Ayesha Syed, John Park, Ashley Hall, Katherine Martucci, et al. “Perioperative neurocognitive and functional neuroimaging trajectories in older APOE4 carriers compared with non-carriers: secondary analysis of a prospective cohort study.” Br J Anaesth 127, no. 6 (December 2021): 917–28. https://doi.org/10.1016/j.bja.2021.08.012.
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  - Whitson, Heather E., Donna Crabtree, Carl F. Pieper, Christine Ha, Sandra Au, Miles Berger, Harvey J. Cohen, et al. “A template for physical resilience research in older adults: Methods of the PRIME-KNEE study.” J Am Geriatr Soc 69, no. 11 (November 2021): 3232–41. https://doi.org/10.1111/jgs.17384.
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  - Meier, Jennie, Audrey Stevens, Miles Berger, Timothy P. Hogan, Joan Reisch, C Munro Cullum, Simon C. Lee, et al. “Racial and Ethnic Disparities in Access to Local Anesthesia for Inguinal Hernia Repair.” J Surg Res 266 (October 2021): 366–72. https://doi.org/10.1016/j.jss.2021.04.026.
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  - Meier, Jennie, Miles Berger, Timothy P. Hogan, Joan Reisch, C Munro Cullum, Simon C. Lee, Celette Sugg Skinner, Herbert Zeh, Cynthia J. Brown, and Courtney J. Balentine. “Local Anesthesia is Associated with Fewer Complications in Umbilical Hernia Repair in Frail Veterans.” J Surg Res 266 (October 2021): 88–95. https://doi.org/10.1016/j.jss.2021.04.006.
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  - Meier, Jennie, Miles Berger, Timothy Hogan, Joan Reisch, Herbert Zeh, C Munro Cullum, Simon C. Lee, Celette Sugg Skinner, Cynthia J. Brown, and Courtney J. Balentine. “Using local rather than general anesthesia for inguinal hernia repair may significantly reduce complications for frail Veterans.” Am J Surg 222, no. 3 (September 2021): 619–24. https://doi.org/10.1016/j.amjsurg.2021.01.026.
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  - Devinney, Michael J., and Miles Berger. “Goldilocks and propofol dosage in older adults: Too much, too little, or just right?” J Am Geriatr Soc 69, no. 8 (August 2021): 2106–9. https://doi.org/10.1111/jgs.17221.
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  - Balentine, Courtney J., Jennie Meier, Miles Berger, Timothy P. Hogan, Joan Reisch, Munro Cullum, Herbert Zeh, Simon C. Lee, Celette Sugg Skinner, and Cynthia J. Brown. “Using local rather than general anesthesia for inguinal hernia repair is associated with shorter operative time and enhanced postoperative recovery.” Am J Surg 221, no. 5 (May 2021): 902–7. https://doi.org/10.1016/j.amjsurg.2020.08.024.
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  - Nobuhara, Chloe Kimi, and Miles Berger. “Risk of Spinal Hematoma After Lumbar Puncture.” Jama 325, no. 8 (February 23, 2021): 787–88. https://doi.org/10.1001/jama.2020.24601.
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  - Terrando, Niccolò, John J. Park, Michael Devinney, Cliburn Chan, Mary Cooter, Pallavi Avasarala, Joseph P. Mathew, et al. “Immunomodulatory lipid mediator profiling of cerebrospinal fluid following surgery in older adults.” Sci Rep 11, no. 1 (February 4, 2021): 3047. https://doi.org/10.1038/s41598-021-82606-5.
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  - Balentine, Courtney J., Jennie Meier, Miles Berger, Joan Reisch, Munro Cullum, Simon C. Lee, Celette Sugg Skinner, and Cynthia J. Brown. “Using Local Anesthesia for Inguinal Hernia Repair Reduces Complications in Older Patients.” J Surg Res 258 (February 2021): 64–72. https://doi.org/10.1016/j.jss.2020.08.054.
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  - Cooter, Mary, Thomas Bunning, Sarada S. Eleswarpu, Mitchell T. Heflin, Shelley McDonald, Sandhya Lagoo-Deenadalayan, Heather Whitson, Stacie G. Deiner, and Miles Berger. “A Processed EEG based Brain Anesthetic Resistance Index Predicts Postoperative Delirium in Older Adults: A Dual Center Study,” January 8, 2021. https://doi.org/10.1101/2021.01.07.21249360.
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  - Acker, Leah, Christine Ha, Junhong Zhou, Brad Manor, Charles M. Giattino, Ken Roberts, Miles Berger, et al. “Electroencephalogram-Based Complexity Measures as Predictors of Post-operative Neurocognitive Dysfunction.” Front Syst Neurosci 15 (2021): 718769. https://doi.org/10.3389/fnsys.2021.718769.
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  - Berger, Miles, Mary Cooter, Alexander S. Roesler, Stacey Chung, John Park, Jennifer L. Modliszewski, Keith W. VanDusen, et al. “APOE4 Copy Number-Dependent Proteomic Changes in the Cerebrospinal Fluid.” J Alzheimers Dis 79, no. 2 (2021): 511–30. https://doi.org/10.3233/JAD-200747.
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  - VanDusen, Keith W., Yi-Ju Li, Victor Cai, Ashley Hall, Sarah Hiles, J Will Thompson, M Arthur Moseley, et al. “Cerebrospinal Fluid Proteome Changes in Older Non-Cardiac Surgical Patients with Postoperative Cognitive Dysfunction.” J Alzheimers Dis 80, no. 3 (2021): 1281–97. https://doi.org/10.3233/JAD-201544.
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  - Velkers, Clive, Miles Berger, Sudeep S. Gill, Roderic Eckenhoff, Heather Stuart, Marlo Whitehead, Peter C. Austin, Paula A. Rochon, and Dallas Seitz. “Association Between Exposure to General Versus Regional Anesthesia and Risk of Dementia in Older Adults.” J Am Geriatr Soc 69, no. 1 (January 2021): 58–67. https://doi.org/10.1111/jgs.16834.
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  - Berger, Miles, and Kamrouz Ghadimi. “Necessary Heroes and Ethos, from Fighting Nazis to COVID-19.” Anesthesiology 133, no. 6 (December 1, 2020): 1307–10. https://doi.org/10.1097/ALN.0000000000003488.
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  - Vasunilashorn, Sarinnapha M., Michael J. Devinney, Leah Acker, Yoojin Jung, Long Ngo, Mary Cooter, Richard Huang, Edward R. Marcantonio, and Miles Berger. “A New Severity Scoring Scale for the 3-Minute Confusion Assessment Method (3D-CAM).” J Am Geriatr Soc 68, no. 8 (August 2020): 1874–76. https://doi.org/10.1111/jgs.16538.
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  - Nobuhara, Chloe K., W Michael Bullock, Thomas Bunning, Brian Colin, Mary Cooter, Michael J. Devinney, Michael N. Ferrandino, et al. “A protocol to reduce self-reported pain scores and adverse events following lumbar punctures in older adults.” J Neurol 267, no. 7 (July 2020): 2002–6. https://doi.org/10.1007/s00415-020-09797-1.
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  - Berger, Miles, Jonathan B. Mark, and Matthias Kreuzer. “Of Parachutes, Speedometers, and EEG: What Evidence Do We Need to Use Devices and Monitors?” Anesth Analg 130, no. 5 (May 2020): 1274–77. https://doi.org/10.1213/ANE.0000000000004653.
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  - Klinger, Rebecca Y., Brandi Bottiger, and Miles Berger. “A Plague on Both Your Monitors! Are Bispectral Index and Cerebral Oximetry Useful for Reducing Postoperative Cognitive Impairment?” J Cardiothorac Vasc Anesth 34, no. 5 (May 2020): 1182–83. https://doi.org/10.1053/j.jvca.2020.01.001.
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  - Wang, Ping, Ravikanth Velagapudi, Cuicui Kong, Ramona M. Rodriguiz, William C. Wetsel, Ting Yang, Miles Berger, Harris A. Gelbard, Carol A. Colton, and Niccolò Terrando. “Neurovascular and immune mechanisms that regulate postoperative delirium superimposed on dementia.” Alzheimers Dement 16, no. 5 (May 2020): 734–49. https://doi.org/10.1002/alz.12064.
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  - Berger, Miles, Mary Cooter, Katherine Ni, Jake Thomas, Dhanesh K. Gupta, and Miklos D. Kertai. “Response to 'Correlation between bispectral index and age-adjusted minimal alveolar concentration' (Br J Anaesth 2020; 124:e8).” Br J Anaesth 124, no. 3 (March 2020): e38–39. https://doi.org/10.1016/j.bja.2019.12.005.
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  - Cooter, Mary, Katherine Ni, Jake Thomas, Dhanesh K. Gupta, Thomas J. Hopkins, Timothy E. Miller, Michael L. James, Miklos D. Kertai, and Miles Berger. “Age-dependent decrease in minimum alveolar concentration of inhaled anaesthetics: a systematic search of published studies and meta-regression analysis.” Br J Anaesth 124, no. 1 (January 2020): e4–7. https://doi.org/10.1016/j.bja.2019.09.036.
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  - VanDusen, Keith W., Sarada Eleswarpu, Eugene W. Moretti, Michael J. Devinney, Donna M. Crabtree, Daniel T. Laskowitz, Marty G. Woldorff, et al. “The MARBLE Study Protocol: Modulating ApoE Signaling to Reduce Brain Inflammation, DeLirium, and PostopErative Cognitive Dysfunction.” J Alzheimers Dis 75, no. 4 (2020): 1319–28. https://doi.org/10.3233/JAD-191185.
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  - Mahanna-Gabrielli, Elizabeth, Katie J. Schenning, Lars I. Eriksson, Jeffrey N. Browndyke, Clinton B. Wright, Deborah J. Culley, Lis Evered, et al. “Corrigendum to 'State of the clinical science of perioperative brain health: report from the American Society of Anesthesiologists Brain Health Initiative Summit 2018' (Br J Anaesth 2019; 123: 464-478).” Br J Anaesth 123, no. 6 (December 2019): 917. https://doi.org/10.1016/j.bja.2019.09.014.
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  - Berger, Miles, David M. Murdoch, Janet S. Staats, Cliburn Chan, Jake P. Thomas, Grant E. Garrigues, Jeffrey N. Browndyke, et al. “Flow Cytometry Characterization of Cerebrospinal Fluid Monocytes in Patients With Postoperative Cognitive Dysfunction: A Pilot Study.” Anesth Analg 129, no. 5 (November 2019): e150–54. https://doi.org/10.1213/ANE.0000000000004179.
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  - Carpenter, Christopher R., Frances McFarland, Michael Avidan, Miles Berger, Sharon K. Inouye, Jason Karlawish, Frank R. Lin, et al. “Impact of Cognitive Impairment Across Specialties: Summary of a Report From the U13 Conference Series.” J Am Geriatr Soc 67, no. 10 (October 2019): 2011–17. https://doi.org/10.1111/jgs.16093.
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  - Mahanna-Gabrielli, Elizabeth, Katie J. Schenning, Lars I. Eriksson, Jeffrey N. Browndyke, Clinton B. Wright, Deborah J. Culley, Lis Evered, et al. “State of the clinical science of perioperative brain health: report from the American Society of Anesthesiologists Brain Health Initiative Summit 2018.” Br J Anaesth 123, no. 4 (October 2019): 464–78. https://doi.org/10.1016/j.bja.2019.07.004.
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  - Berger, Miles, Martin S. Angst, Deborah J. Culley, Catherine E. Price, David A. Scott, Robert A. Whittington, Roderic G. Eckenhoff, and Roderic G. Perioperative Neurotoxicity Working Group. “In Response.” Anesth Analg 129, no. 3 (September 2019): e112–13. https://doi.org/10.1213/ANE.0000000000004300.
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  - Ni, Katherine, Mary Cooter, Dhanesh K. Gupta, Jake Thomas, Thomas J. Hopkins, Timothy E. Miller, Michael L. James, Miklos D. Kertai, and Miles Berger. “Paradox of age: older patients receive higher age-adjusted minimum alveolar concentration fractions of volatile anaesthetics yet display higher bispectral index values.” Br J Anaesth 123, no. 3 (September 2019): 288–97. https://doi.org/10.1016/j.bja.2019.05.040.
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  - Klinger, Rebecca Y., Mary Cooter, Tiffany Bisanar, Niccolò Terrando, Miles Berger, Mihai V. Podgoreanu, Mark Stafford-Smith, Mark F. Newman, Joseph P. Mathew, and Joseph P. Neurologic Outcomes Research Group of the Duke Heart Center. “Intravenous Lidocaine Does Not Improve Neurologic Outcomes after Cardiac Surgery: A Randomized Controlled Trial.” Anesthesiology 130, no. 6 (June 2019): 958–70. https://doi.org/10.1097/ALN.0000000000002668.
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  - Berger, Miles, Deborah Oyeyemi, Mobolaji O. Olurinde, Heather E. Whitson, Kent J. Weinhold, Marty G. Woldorff, Lewis A. Lipsitz, et al. “The INTUIT Study: Investigating Neuroinflammation Underlying Postoperative Cognitive Dysfunction.” J Am Geriatr Soc 67, no. 4 (April 2019): 794–98. https://doi.org/10.1111/jgs.15770.
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  - Yang, T., G. Xu, P. T. Newton, A. S. Chagin, S. Mkrtchian, M. Carlström, X. -. M. Zhang, et al. “Maresin 1 attenuates neuroinflammation in a mouse model of perioperative neurocognitive disorders.” Br J Anaesth 122, no. 3 (March 2019): 350–60. https://doi.org/10.1016/j.bja.2018.10.062.
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  - Brinkley, Tina E., Miles Berger, Kathryn E. Callahan, Robert A. Fieo, Lee A. Jennings, Jill K. Morris, Heather M. Wilkins, and Stephen B. Kritchevsky. “Corrigendum to: Workshop on Synergies Between Alzheimer's Research and Clinical Gerontology and Geriatrics: Current Status and Future Directions.” J Gerontol a Biol Sci Med Sci 74, no. 3 (February 15, 2019): 432. https://doi.org/10.1093/gerona/gly156.
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  - Smith, Patrick J., Jeffrey N. Browndyke, Zachary A. Monge, Todd B. Harshbarger, Michael L. James, Jeffrey G. Gaca, John H. Alexander, et al. “Longitudinal Changes in Regional Cerebral Perfusion and Cognition After Cardiac Operation.” Ann Thorac Surg 107, no. 1 (January 2019): 112–18. https://doi.org/10.1016/j.athoracsur.2018.07.056.
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  - Berger, Miles, Katie J. Schenning, Charles H. Brown, Stacie G. Deiner, Robert A. Whittington, Roderic G. Eckenhoff, Martin S. Angst, et al. “Best Practices for Postoperative Brain Health: Recommendations From the Fifth International Perioperative Neurotoxicity Working Group.” Anesth Analg 127, no. 6 (December 2018): 1406–13. https://doi.org/10.1213/ANE.0000000000003841.
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  - Evered, L., B. Silbert, D. S. Knopman, D. A. Scott, S. T. DeKosky, L. S. Rasmussen, E. S. Oh, et al. “Recommendations for the nomenclature of cognitive change associated with anaesthesia and surgery-2018.” Br J Anaesth 121, no. 5 (November 2018): 1005–12. https://doi.org/10.1016/j.bja.2017.11.087.
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  - Evered, L., B. Silbert, D. S. Knopman, D. A. Scott, S. T. DeKosky, L. S. Rasmussen, E. S. Oh, et al. “Recommendations for the nomenclature of cognitive change associated with anaesthesia and surgery-2018.” Can J Anaesth 65, no. 11 (November 2018): 1248–57. https://doi.org/10.1007/s12630-018-1216-x.
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  - Evered, L., B. Silbert, D. S. Knopman, D. A. Scott, S. T. DeKosky, L. S. Rasmussen, E. S. Oh, et al. “Recommendations for the Nomenclature of Cognitive Change Associated with Anaesthesia and Surgery-2018.” Anesthesiology 129, no. 5 (November 2018): 872–79. https://doi.org/10.1097/ALN.0000000000002334.
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  - Evered, L., B. Silbert, D. S. Knopman, D. A. Scott, S. T. DeKosky, L. S. Rasmussen, E. S. Oh, et al. “Recommendations for the Nomenclature of Cognitive Change Associated With Anaesthesia and Surgery-2018.” Anesth Analg 127, no. 5 (November 2018): 1189–95. https://doi.org/10.1213/ANE.0000000000003634.
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  - Evered, Lis, Brendan Silbert, David S. Knopman, David A. Scott, Steven T. DeKosky, Lars S. Rasmussen, Esther S. Oh, et al. “Recommendations for the nomenclature of cognitive change associated with anaesthesia and surgery-2018.” Acta Anaesthesiol Scand 62, no. 10 (November 2018): 1473–80. https://doi.org/10.1111/aas.13250.
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  - Berger, Miles, Niccolò Terrando, S Kendall Smith, Jeffrey N. Browndyke, Mark F. Newman, and Joseph P. Mathew. “Neurocognitive Function after Cardiac Surgery: From Phenotypes to Mechanisms.” Anesthesiology 129, no. 4 (October 2018): 829–51. https://doi.org/10.1097/ALN.0000000000002194.
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  - Devinney, Michael J., Joseph P. Mathew, and Miles Berger. “Postoperative Delirium and Postoperative Cognitive Dysfunction: Two Sides of the Same Coin?” Anesthesiology 129, no. 3 (September 2018): 389–91. https://doi.org/10.1097/ALN.0000000000002338.
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  - Brinkley, Tina E., Miles Berger, Kathryn E. Callahan, Robert A. Fieo, Lee A. Jennings, Jill K. Morris, Heather M. Wilkins, and Stephen B. Kritchevsky. “Workshop on Synergies Between Alzheimer's Research and Clinical Gerontology and Geriatrics: Current Status and Future Directions.” J Gerontol a Biol Sci Med Sci 73, no. 9 (August 10, 2018): 1229–37. https://doi.org/10.1093/gerona/gly041.
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  - Cobb, Mary In-Ping Huang, Matthew Crowson, Rachael Mintz-Cole, Aatif M. Husain, Miles Berger, David Jang, and Patrick Codd. “Transnasal Transsphenoidal Elevation of Optic Chiasm in Secondary Empty Sella Syndrome Following Prolactinoma Treatment.” World Neurosurg 112 (April 2018): 250–53. https://doi.org/10.1016/j.wneu.2018.01.202.
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  - Klinger, Rebecca Y., Olga G. James, Salvador Borges-Neto, Tiffany Bisanar, Yi-Ju Li, Wenjing Qi, Miles Berger, et al. “18F-florbetapir Positron Emission Tomography-determined Cerebral β-Amyloid Deposition and Neurocognitive Performance after Cardiac Surgery.” Anesthesiology 128, no. 4 (April 2018): 728–44. https://doi.org/10.1097/ALN.0000000000002103.
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  - Browndyke, Jeffrey N., Miles Berger, Patrick J. Smith, Todd B. Harshbarger, Zachary A. Monge, Viral Panchal, Tiffany L. Bisanar, et al. “Task-related changes in degree centrality and local coherence of the posterior cingulate cortex after major cardiac surgery in older adults.” Hum Brain Mapp 39, no. 2 (February 2018): 985–1003. https://doi.org/10.1002/hbm.23898.
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  - Evered, L., B. Silbert, D. S. Knopman, D. A. Scott, S. T. DeKosky, L. S. Rasmussen, E. S. Oh, et al. “Recommendations for the Nomenclature of Cognitive Change Associated with Anaesthesia and Surgery-20181.” J Alzheimers Dis 66, no. 1 (2018): 1–10. https://doi.org/10.3233/JAD-189004.
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  - Crowson, Matthew Gordon, Miles Berger, Grace C. McCarthy, and David B. Powers. “Orbitocerebral Impalement: Case Discussion and Management Algorithm.” Craniomaxillofac Trauma Reconstr 10, no. 3 (September 2017): 225–29. https://doi.org/10.1055/s-0036-1592098.
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  - Berger, Miles, Vikram Ponnusamy, Nathaniel Greene, Mary Cooter, Jacob W. Nadler, Allan Friedman, David L. McDonagh, et al. “The Effect of Propofol vs. Isoflurane Anesthesia on Postoperative Changes in Cerebrospinal Fluid Cytokine Levels: Results from a Randomized Trial.” Front Immunol 8 (2017): 1528. https://doi.org/10.3389/fimmu.2017.01528.
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  - Browndyke, Jeffrey N., Miles Berger, Todd B. Harshbarger, Patrick J. Smith, William White, Tiffany L. Bisanar, John H. Alexander, et al. “Resting-State Functional Connectivity and Cognition After Major Cardiac Surgery in Older Adults without Preoperative Cognitive Impairment: Preliminary Findings.” J Am Geriatr Soc 65, no. 1 (January 2017): e6–12. https://doi.org/10.1111/jgs.14534.
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  - Giattino, Charles M., Jacob E. Gardner, Faris M. Sbahi, Kenneth C. Roberts, Mary Cooter, Eugene Moretti, Jeffrey N. Browndyke, et al. “Intraoperative Frontal Alpha-Band Power Correlates with Preoperative Neurocognitive Function in Older Adults.” Front Syst Neurosci 11 (2017): 24. https://doi.org/10.3389/fnsys.2017.00024.
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  - Klinger, Rebecca Y., Mary Cooter, Miles Berger, Mihai V. Podgoreanu, Mark Stafford-Smith, Thomas L. Ortel, Ian J. Welsby, et al. “Effect of intravenous lidocaine on the transcerebral inflammatory response during cardiac surgery: a randomized-controlled trial.” Can J Anaesth 63, no. 11 (November 2016): 1223–32. https://doi.org/10.1007/s12630-016-0704-0.
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  - Berger, Miles, and Paul S. García. “Anesthetic Suppression of Thalamic High-Frequency Oscillations: Evidence that the Thalamus Is More Than Just a Gateway to Consciousness?” Anesth Analg 122, no. 6 (June 2016): 1737–39. https://doi.org/10.1213/ANE.0000000000001207.
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  - Berger, Miles, Jacob W. Nadler, Allan Friedman, David L. McDonagh, Ellen R. Bennett, Mary Cooter, Wenjing Qi, et al. “The Effect of Propofol Versus Isoflurane Anesthesia on Human Cerebrospinal Fluid Markers of Alzheimer's Disease: Results of a Randomized Trial.” J Alzheimers Dis 52, no. 4 (April 15, 2016): 1299–1310. https://doi.org/10.3233/JAD-151190.
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  - Berger, Miles, Jacob W. Nadler, Jeffrey Browndyke, Niccolo Terrando, Vikram Ponnusamy, Harvey Jay Cohen, Heather E. Whitson, and Joseph P. Mathew. “Postoperative Cognitive Dysfunction: Minding the Gaps in Our Knowledge of a Common Postoperative Complication in the Elderly.” Anesthesiol Clin 33, no. 3 (September 2015): 517–50. https://doi.org/10.1016/j.anclin.2015.05.008.
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  - Berger, Miles, Jeffrey Browndyke, and Joseph P. Mathew. “Intraoperative Glycemic Control to Prevent Delirium after Cardiac Surgery: Steering a Course between Scylla and Charybdis.” Anesthesiology 122, no. 6 (June 2015): 1186–88. https://doi.org/10.1097/ALN.0000000000000670.
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  - Berger, Miles, David W. Scheel, Hector Macias, Takeshi Miyatsuka, Hail Kim, Phuong Hoang, Greg M. Ku, et al. “Gαi/o-coupled receptor signaling restricts pancreatic β-cell expansion.” Proc Natl Acad Sci U S A 112, no. 9 (March 3, 2015): 2888–93. https://doi.org/10.1073/pnas.1319378112.
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  - Patterson, S. C., S. G. Kwatra, M. Berger, and M. M. Kwatra. “Delirium and Obstructive Sleep Apnea: Exploring the Molecular Link.” Current Anesthesiology Reports 5, no. 1 (March 1, 2015): 41–47. https://doi.org/10.1007/s40140-014-0092-3.
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  - Berger, Miles, James Burke, Roderick Eckenhoff, and Joseph Mathew. “Alzheimer's disease, anesthesia, and surgery: a clinically focused review.” J Cardiothorac Vasc Anesth 28, no. 6 (December 2014): 1609–23. https://doi.org/10.1053/j.jvca.2014.04.014.
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  - McDonagh, David L., Miles Berger, Joseph P. Mathew, Carmelo Graffagnino, Carmelo A. Milano, and Mark F. Newman. “Neurological complications of cardiac surgery.” Lancet Neurol 13, no. 5 (May 2014): 490–502. https://doi.org/10.1016/S1474-4422(14)70004-3.
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  - Berger, Miles, Jacob Nadler, and Joseph P. Mathew. “Preventing delirium after cardiothoracic surgery: provocative but preliminary evidence for bispectral index monitoring.” Anesth Analg 118, no. 4 (April 2014): 706–7. https://doi.org/10.1213/ANE.0000000000000130.
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  - Berger, M., B. Philips-Bute, J. Guercio, T. J. Hopkins, M. L. James, C. O. Borel, D. S. Warner, and D. L. McDonagh. “A novel application for bolus remifentanil: blunting the hemodynamic response to Mayfield skull clamp placement.” Curr Med Res Opin 30, no. 2 (February 2014): 243–50. https://doi.org/10.1185/03007995.2013.855190.
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  - Berger, Miles, David S. Warner, and David L. McDonagh. “Volatile anesthetic sedation during therapeutic hypothermia after cardiac arrest in the ICU: a journey of a thousand miles begins with a single step.” Crit Care Med 42, no. 2 (February 2014): 494–95. https://doi.org/10.1097/01.ccm.0000435689.93091.d0.
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  - Khan, Shariq Ali, Miles Berger, Abhishek Agrawal, Mary Huang, Isaac Karikari, Shahid M. Nimjee, Ali R. Zomorodi, and David L. McDonagh. “Rapid ventricular pacing assisted hypotension in the management of sudden intraoperative hemorrhage during cerebral aneurysm clipping.” Asian J Neurosurg 9, no. 1 (January 2014): 33–35. https://doi.org/10.4103/1793-5482.131066.
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  - Hussain, Maria, Miles Berger, Roderic G. Eckenhoff, and Dallas P. Seitz. “General anesthetic and the risk of dementia in elderly patients: current insights.” Clin Interv Aging 9 (2014): 1619–28. https://doi.org/10.2147/CIA.S49680.
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  - Ishida, Kazuyoshi, Miles Berger, Jacob Nadler, and David S. Warner. “Anesthetic neuroprotection: antecedents and an appraisal of preclinical and clinical data quality.” Curr Pharm Des 20, no. 36 (2014): 5751–65. https://doi.org/10.2174/1381612820666140204111701.
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  - Mathew, Joseph P., William D. White, David B. Schinderle, Mihai V. Podgoreanu, Miles Berger, Carmelo A. Milano, Daniel T. Laskowitz, et al. “Intraoperative magnesium administration does not improve neurocognitive function after cardiac surgery.” Stroke 44, no. 12 (December 2013): 3407–13. https://doi.org/10.1161/STROKEAHA.113.002703.
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  - Honig, Gerard, Angela Liou, Miles Berger, Michael S. German, and Laurence H. Tecott. “Precise pattern of recombination in serotonergic and hypothalamic neurons in a Pdx1-cre transgenic mouse line.” J Biomed Sci 17, no. 1 (October 17, 2010): 82. https://doi.org/10.1186/1423-0127-17-82.
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  - Berger, Miles, John A. Gray, and Bryan L. Roth. “The expanded biology of serotonin.” Annu Rev Med 60 (2009): 355–66. https://doi.org/10.1146/annurev.med.60.042307.110802.
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  - Kushwaha, Neena, Shannon C. Harwood, Ariel M. Wilson, Miles Berger, Laurence H. Tecott, Bryan L. Roth, and Paul R. Albert. “Molecular determinants in the second intracellular loop of the 5-hydroxytryptamine-1A receptor for G-protein coupling.” Mol Pharmacol 69, no. 5 (May 2006): 1518–26. https://doi.org/10.1124/mol.105.019844.
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  - Berger, Miles, Sadna Budhu, Emily Lu, Yongmei Li, Devora Loike, Samuel C. Silverstein, and John D. Loike. “Different G(i)-coupled chemoattractant receptors signal qualitatively different functions in human neutrophils.” J Leukoc Biol 71, no. 5 (May 2002): 798–806.
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- Book Sections
  - Schenning, Katie J., and Miles Berger. “Postoperative Neurocognitive Disorders in the Geriatric Patient.” In Essentials of Neurosurgical Anesthesia & Critical Care, 105–7. Springer International Publishing, 2020. https://doi.org/10.1007/978-3-030-17410-1_15.
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  - Berger, M., S. Kendall Smith, and A. Khan. “Biomarkers of Postoperative Cognitive Dysfunction: Finding the Signal amid the Noise.” In The Perioperative Neurocognitive Disorders, 134–51, 2019. https://doi.org/10.1017/9781316402504.013.
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  - Doshi, A., R. Cabeza, and M. Berger. “Geriatric anesthesia: Age-dependent changes in the central and peripheral nervous systems.” In Geriatric Anesthesiology: Third Edition, 145–60, 2017. https://doi.org/10.1007/978-3-319-66878-9_10.
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  - Berger, M., and B. Roth. “Pharmacology of serotonergic and central adrenergic neurotransmission.” In Principles of Pharmacology: The Pathophysiologic Basis of Drug Therapy: Third Edition, 481–519, 2012.
- Conference Papers
  - Acker, Leah, Sandra Au, Kenneth Roberts, Charlie Giattino, Eugene Moretti, Michael Devinney, Melody Reese, et al. “Preoperative EEG Inattention Signatures and Postoperative Delirium.” In Anesthesia and Analgesia, 134:496–496, 2022.
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  - Avasarala, Pallavi, Jake Thomas, Andrew R. Spector, Jeffrey N. Browndyke, Patrick J. Smith, Jennifer Dominguez, Mary Cooter, et al. “The SANDMAN Study: Sleep Apnea, Neuroinflammation, and Cognitive Dysfunction Manifesting After Non-cardiac surgery.” In Anesthesia and Analgesia, 134:1100–1102, 2022.
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  - Reese, Melody, Ken Roberts, Marty G. Woldorff, Mary Cooter, Leah Acker, Sophie Wu, Heather E. Whitson, and Miles Berger. “Machine learning XGBoost classification of postoperative delirium by intraoperative EEG metrics.” In Anesthesia and Analgesia, 134:609–11, 2022.
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  - Thomas, Jake, David Corcoran, Matthew Fuller, Arthur Moseley, Mary Cooter, Michael Lutz, Joseph P. Mathew, Miles Berger, and Michael Devinney. “Pre- and Postoperative CSF Proteomic Signatures of Postoperative Delirium.” In Anesthesia and Analgesia, 134:467–70, 2022.
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  - Villalobos, Daniel, Miles Berger, Mary Cooter, Jeffrey N. Browndyke, Ayesha Syed, Eugene Moretti, and Michael Divinney. “Perioperative neurocognitive and CSF Alzheimer's biomarker trajectories in older patients randomized to Isoflurane or Propofol for Anaesthetic Maintenance.” In Anesthesia and Analgesia, 134:488–90, 2022.
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  - Wong, Megan, Melody Reese, Mary Cooter, Jeffrey N. Browndyke, Joseph P. Mathew, Harvey J. Cohen, Heather E. Whitson, and Miles Berger. “Cognitive and cerebrospinal fluid Alzheimer's Disease biomarker changes over time in older surgical patients and matched nonsurgical controls.” In Anesthesia and Analgesia, 134:954–56, 2022.
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  - Au, S., K. Roberts, M. Cooler, L. Acker, C. Ha, M. Woldorff, C. Colon-Emeric, H. Whitson, and M. Berger. “Preoperative EEG: A Potential Predictor of Postoperative Delirium in Older Adults.” In Journal of the American Geriatrics Society, 69:S222–23, 2021.
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  - Meier, Jennie, Audrey R. Stevens, Miles Berger, Munro Cullum, Cynthia J. Brown, and Courtney Balentine. “Locoregional Anesthesia for Major Surgery in Frail Adults May Reduce Postoperative Morbidity and Mortality.” In Journal of the American College of Surgeons, 233:E62–E62, 2021.
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  - Yang, Rosa O., Jeffrey N. Browndyke, Mary Cooter, and Miles Berger. “Perioperative neurocognitive and neuroimaging trajectories in older APOE4 carriers vs non-carriers: A prospective cohort study.” In Anesthesia and Analgesia, 132:545–46, 2021.
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  - Ha, C., C. Giattino, J. Zhou, M. Cooter, K. Roberts, D. Crabtree, D. Oyeyemi, et al. “Postoperative Resilience in Older People: An EEG Complexity Measure Predicts Postoperative Attention Deficits.” In Journal of the American Geriatrics Society, 68:S179–S179. WILEY, 2020.
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  - Devinney, Michael, Andrew R. Spector, Jeffrey N. Browndyke, Patrick J. Smith, Jennifer Dominguez, Anesthesio M. Dominguez, Mary Cooter, et al. “The SANDMAN Study: Sleep Apnea, Neuroinflammation, and Cognitive Dysfunction Manifesting After Non-cardiac surgery.” In Anesthesia and Analgesia, 130:514–15, 2020.
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  - Eleswarpu, Sarada, Miles Berger, Mary Cooter, Ankeet D. Udani, Mitchell T. Heflin, Shahrukh Bengali, Anna Ray, and Sarah Wingfield. “Developing a Real-time EEG-guided Anesthesia Management curriculum for Educating Residents (DREAMER): A randomized controlled trial.” In Anesthesia and Analgesia, 130:413–413, 2020.
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  - Ha, Christine, Vanessa Cheong, Mary Cooter, Jeffrey N. Browndyke, Eugene Moretti, W. M. Bullock, Brian J. Colin, et al. “Cognitive and Cerebrospinal fluid Alzheimer's Disease biomarker changes over time in older surgical patients and matched nonsurgical controls.” In Anesthesia and Analgesia, 130:502–502, 2020.
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  - Meier, Jennie, Miles Berger, Munro Cullum, Simon C. Lee, Herbert J. Zeh, Cynthia Brown, and Courtney Balentine. “Local Anesthesia Can Reduce Complications in Adults Undergoing Umbilical Hernia Repair.” In Journal of the American College of Surgeons, 231:S100–101, 2020.
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  - VanDusen, Keith W., Sarada Eleswarpu, Eugene Moretti, Michael Devinney, Ken Roberts, Mary Cooter, Daniel T. Laskowitz, Frank W. Rockhold, and Miles Berger. “The MARBLE Study: Modulating ApoE signaling to Reduce Brain inflammation, deLirium, and postopErative Cognitive Dysfunction.” In Anesthesia and Analgesia, 130:432–33, 2020.
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  - Devinney, M. J., P. J. Smith, A. R. Spector, Y. Cheong, V. A. Wickenheisser, J. N. Browndyke, M. Cooter, J. P. Mathew, and M. Berger. “The Association of Obstructive Sleep Apnea Risk with Postoperative Cognitive Decline.” In Journal of the American Geriatrics Society, 67:S178–S178. WILEY, 2019.
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  - Oyeyemi, D., H. Whitson, J. N. Browndyke, H. J. Cohen, J. P. Mathew, and M. Berger. “Depression, Anxiety and Postoperative Cognition in Older Adults.” In Journal of the American Geriatrics Society, 67:S338–S338. WILEY, 2019.
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  - Acker, Leah, Miles Berger, Junhong Zhou, Lewis Lipsitz, Marty G. Woldorff, and Heather E. Whitson. “INTRA-OPERATIVE ELECTROENCEPHALOGRAM CORRELATES OF POST-OPERATIVE NEUROCOGNITIVE RESILIENCE IN OLDER ADULTS.” In Anesthesia and Analgesia, 128:489–489, 2019.
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  - Bunning, Thomas, Heather E. Whitson, Kent Weinhold, Marty G. Woldorff, Eugene Moretti, Deborah Oyeyemi, Mary Cooter, et al. “THE INTUIT STUDY: INVESTIGATING NEUROINFLAMMATION UNDERLYING POSTOPERATIVE NEUROCOGNITIVE DYSFUNCTION AND DELIRIUM IN OLDER ADULTS.” In Anesthesia and Analgesia, 128:432–432, 2019.
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  - Devinney, Michael, Andrew R. Spector, Jeffrey N. Browndyke, Patrick J. Smith, Jennifer Dominguez, Thomas Bunning, Mary Cooter, Joseph P. Mathew, and Miles Berger. “THE SANDMAN STUDY: SLEEP APNEA, NEUROINFLAMMATION, AND COGNITIVE DYSFUNCTION MANIFESTING AFTER NON-CARDIAC SURGERY.” In Anesthesia and Analgesia, 128:918–918, 2019.
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  - Devinney, Michael, Krishna Rao Maddipati, Cliburn Chan, Joseph P. Mathew, Mary Cooter, Niccolo Terrando, and Miles Berger. “METABOLIPIDOMIC ANALYSIS OF CEREBROSPINAL FLUID REVEALS INCREASED ARACHIDONIC ACID-DERIVED LIPIDS AND SPECIALIZED PRO-RESOLVING MEDIATORS 24 HRS AND 6-WEEKS FOLLOWING SURGERY AND ANESTHESIA.” In Anesthesia and Analgesia, 128:485–86, 2019.
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  - Cheong, Yee Ching Vanessa, Mary Cooter, Richard L. Huang, Heather E. Whitson, Harvey J. Cohen, Joseph P. Mathew, and Miles Berger. “PERIOPERATIVE TRAJECTORY OF ALZHEIMER'S DISEASE BIOMARKERS IN SURGICAL PATIENTS AND MATCHED NON-SURGICAL CONTROLS.” In Anesthesia and Analgesia, 126:353–56. LIPPINCOTT WILLIAMS & WILKINS, 2018.
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  - Devinney, M. J., M. Mclawhorn, B. Taicher, J. Hunting, and M. Berger. “Comparing CAM-ICU and 3D-CAM as early postoperative delirium screening tools.” In Journal of the American Geriatrics Society, 66:S172–73. WILEY, 2018.
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  - Devinney, Michael, Yee Ching Vanessa Cheong, Victoria Wickenheisser, Mary Cooter, Jennifer Dominguez, and Miles Berger. “IS OBSTRUCTIVE SLEEP APNEA ASSOCIATED WITH POSTOPERATIVE DELIRIUM AND COGNITIVE DECLINE?” In Anesthesia and Analgesia, 126:704–5. LIPPINCOTT WILLIAMS & WILKINS, 2018.
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  - Berger, M., J. Browndyke, M. Cooter, W. Bullock, B. Colin, J. Gadsden, E. Iboaya, et al. “Postoperative Changes in CSF AD Markers, Cognition, and fMRI activity.” In Journal of the American Geriatrics Society, 66:S5–S5. WILEY, 2018.
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  - Bottiger, B., J. Klapper, V. Esposito, N. Hashmi, M. Berger, and P. Smith. “Posterior Reversible Encephalopathy Syndrome After Lung Transplant: Clinical Characteristics and Outcomes.” In The Journal of Heart and Lung Transplantation, 37:S252–53. Elsevier BV, 2018. https://doi.org/10.1016/j.healun.2018.01.628.
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  - Berger, M., K. Ni, and M. Cooter. “AGE DEPENDENT TRENDS IN ANESTHETIC ADMINISTRATION, AND THE AGE DEPENDENT DECREASE IN MAC: A SINGLE CENTER RETROSPECTIVE STUDY AND REGRESSION ANALYSIS OF PUBLISHED STUDIES.” In Anesthesia and Analgesia, Vol. 122. LIPPINCOTT WILLIAMS & WILKINS, 2016.
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  - Berger, M., P. J. Smith, F. Sbahi, J. Thomas, L. Snyder, and J. Blumenthal. “INTRAVENOUS IMMUNOGLOBULIN ADMINISTRATION IS ASSOCIATED WITH REDUCED DELIRIUM RATE AND DECREASED DELIRIUM DURATION IN LUNG TRANSPLANT RECIPIENTS- A SINGLE CENTER RETROSPECTIVE STUDY.” In Anesthesia and Analgesia, Vol. 122. LIPPINCOTT WILLIAMS & WILKINS, 2016.
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  - Raghunathan, K., S. L. McCartney, A. Barbeito, V. Khangulov, F. Peyerl, M. Berger, and A. Shaw. “ACUTE KIDNEY INJURY AFTER CARDIAC SURGERY AMONG PATIENTS WITH AND WITHOUT PREEXISTING CHRONIC KIDNEY DISEASE: EFFECTS OF PERIOPERATIVE CRYSTALLOID CHOICE.” In Anesthesia and Analgesia, Vol. 122. LIPPINCOTT WILLIAMS & WILKINS, 2016.
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  - Simon, George R., Daniel Gomez, Mara B. Antonoff, Nguyen Quynh-Nhu, Emily Roarty, Kathryn A. Gold, Sunil Patel, et al. “MD Anderson Oncology Expert Advisor (TM) System (OEA (TM)): A Cognitive Computing Recommendations Application (App) for Lung Cancer.” In Journal of Thoracic Oncology, 10:S536–S536. ELSEVIER SCIENCE INC, 2015.
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  - Ford, Joel, Michael Berger, and Jillian L. Goldfarb. “Fabrication of activated biochars from avocado pits and their adsorption capacity for oxytetracycline from wastewater.” In Abstracts of Papers of the American Chemical Society, Vol. 248. AMER CHEMICAL SOC, 2014.
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  - Berger, M., D. McDonagh, J. Mathew, M. Newman, and M. James. “THE EFFECT OF PROPOFOL VERSUS ISOFLURANE ANESTHESIA ON HUMAN CSF MARKERS OF ALZHEIMER'S DISEASE- PRELIMINARY RESULTS OF A RANDOMIZED CONTROLLED TRIAL.” In Anesthesia and Analgesia, 116:162–162. LIPPINCOTT WILLIAMS & WILKINS, 2013.
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  - Lade, Amanda T., Michael Berger, Jillian L. Goldfarb, and Li Buessing. “Toxic gold? Bioavailability of olive oil waste phenols to plant matter.” In Abstracts of Papers of the American Chemical Society, Vol. 243. AMER CHEMICAL SOC, 2012.
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  - Metzger, Kayla L., Lyngine H. Calizo, Alisson Stephen, Miles Berger, Laurence H. Tecott, and Sheryl G. Beck. “Expression level of 5-HT1A receptor alters firing rate and concentration-dependency in YFP-labeled 5-HT dorsal raphe neurons.” In Faseb Journal, Vol. 22. FEDERATION AMER SOC EXP BIOL, 2008.
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  - Loike, J. D., M. Berger, E. Lu, Y. M. Li, D. Loike, S. Budhu, and S. C. Silverstein. “Different Gi-coupled chemoattractant receptors signal qualitatively distinct functions in human neutrophils.” In Molecular Biology of the Cell, 12:324A-324A. AMER SOC CELL BIOLOGY, 2001.
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  - Berger, M., Y. M. Li, S. Budhu, S. C. Silverstein, and J. D. Loike. “Chemoattractant activation of beta(2) integrins and 5-lipoxygenase regulates neutrophil adhesion, migration oxidative burst.” In Molecular Biology of the Cell, 10:318A-318A. AMER SOC CELL BIOLOGY, 1999.
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- Summer Neuroscience Program Mentor. Summer Neuroscience Program. 2021 - 2022 2021 - 2022
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