Mitchell Amuda Mah'moud | Scholars@Duke

Mitchell Amuda Mah'moud
Consulting Professor in the Department of Medicine

My research focuses on Hepatitis C management including new treatment options and possible complications. In addition, I am also interested in studying NAFLD including risk factors, new treatment modalities and economic impact on the society. As a member of the African Liver Cancer Consortium, I am involved in investigating the etiological factors and treatment options of hepatoma in Africa in the context of limited resources.
In addition to my research activities, I have been involved in teaching and mentoring the GI fellows. Nationally, I have served on several society committees including the Annual Meeting Educational Committee of AASLD, Professional Issues Committee of ACG and the Ethics Committee of the AGA. I was a founding member of the Executive Management Board of the AGA Center for GI Innovation and Technology.

Current Research Interests

My research interest includes Hepatitis C treatment options and complications. In addition, I am also interested in studying metabolic liver diseases especially NAFLD including the risk factors, new treatment modalities and longterm complications. As a member of the African Liver Cancer Consortium, I am also investigating the etiological factors and management options of hepatoma in Africa in the context of limited resources.

Office Hours

8am to 5pm

Current Appointments & Affiliations

Consulting Professor in the Department of Medicine, Medicine, Gastroenterology, Medicine 2019

Contact Information

03107 Hospital South, Box 3913 Med Ctr, Durham, NC 27710
mitchell.mah.moud@duke.edu (252) 937-0231
My CV

Background
Education, Training, & Certifications
- Fellow in Gastroenterology, Medicine, Yale University 1994 - 1997
- Resident, Medicine, Johns Hopkins University 1991 - 1994
- M.D., University of Ibadan, College of Medicine (Nigeria) 1989
Medical Licensure
- 97-00651. North Carolina. 2018
Previous Appointments & Affiliations
- Assistant Consulting Professor in the Department of Medicine, Gastroenterology, Medicine, Gastroenterology, Medicine 2008 - 2019
Academic Positions Outside Duke
- Assistant Professor of Medicine, University of South Carolina Medical School. 1997 - 2000
- Clinical Instructor in Medicine, Department of Medicine, Yale Medical School. 1996 - 1997
- Lecturer, Physician Assistant Program, Yale Medical School. 1995 - 1997
Recognition
Awards & Honors
Expertise
Global Scholarship
- Teaching
  - Ghana (Country)
  - Nigeria (Country)
Research
Fellowships, Supported Research, & Other Grants
- Intercept 747-303 awarded by Intercept Pharmaceuticals, Inc 2018 - 2024
- Intercept 747-304 awarded by Intercept Pharmaceuticals, Inc 2017 - 2021
- Gilead US 384-1944 awarded by Gilead Sciences, Inc 2017 - 2022
- Gilead US 384-1943 awarded by Gilead Sciences, Inc 2017 - 2025
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Bailey, Donald E., Andrew J. Muir, Michael P. Cary, Natalie Ammarell, Sarah Seaver, Emily Scirica, Mitch Mah’moud, and Ruth A. Anderson. “Adaptive Challenges and Family Support: Patient Self-Management during Treatment for Chronic Hepatitis C.” Nurs Sci Q 34, no. 4 (October 2021): 405–12. https://doi.org/10.1177/08943184211031602.
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  - Yang, Ju Dong, Essa A. Mohamed, Ashraf O Abdel Aziz, Hend I. Shousha, Mohamed B. Hashem, Mohamed M. Nabeel, Ahmed H. Abdelmaksoud, et al. “Characteristics, management, and outcomes of patients with hepatocellular carcinoma in Africa: a multicountry observational study from the Africa Liver Cancer Consortium.” Lancet Gastroenterol Hepatol 2, no. 2 (February 2017): 103–11. https://doi.org/10.1016/S2468-1253(16)30161-3.
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  - Alam, Imtiaz, Kimberley Brown, Cynthia Donovan, Jamie Forlenza, Kris Lauwers, Mitchell A. Mah’moud, Richard Manch, et al. “Real-World Effectiveness of Simeprevir-containing Regimens Among Patients With Chronic Hepatitis C Virus: The SONET Study.” Open Forum Infect Dis 4, no. 1 (2017): ofw258. https://doi.org/10.1093/ofid/ofw258.
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  - Mah’moud, Mitchell A. “Current Management of Hepatitis C Virus Infection.” N C Med J 77, no. 3 (2016): 188–93. https://doi.org/10.18043/ncm.77.3.188.
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  - Sterling, R. K., A. Kuo, V. K. Rustgi, M. S. Sulkowski, T. G. Stewart, J. M. Fenkel, H. El-Genaidi, et al. “Virological outcomes and treatment algorithms utilisation in observational study of patients with chronic hepatitis C treated with boceprevir or telaprevir.” Aliment Pharmacol Ther 41, no. 7 (April 2015): 671–85. https://doi.org/10.1111/apt.13095.
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  - Banks, Peter A., Thomas L. Bollen, Christos Dervenis, Hein G. Gooszen, Colin D. Johnson, Michael G. Sarr, Gregory G. Tsiotos, Santhi Swaroop Vege, and Santhi Swaroop Acute Pancreatitis Classification Working Group. “Classification of acute pancreatitis--2012: revision of the Atlanta classification and definitions by international consensus.” Gut 62, no. 1 (January 2013): 102–11. https://doi.org/10.1136/gutjnl-2012-302779.
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  - Dutta, Sudhir K., Kireet Agrawal, Mohit Girotra, A Steven Fleisher, Mahnaz Motevalli, Mitchell A. Mah’moud, and Padmanabhan P. Nair. “Barrett's esophagus and β-carotene therapy: symptomatic improvement in GERD and enhanced HSP70 expression in esophageal mucosa.” Asian Pac J Cancer Prev 13, no. 12 (2012): 6011–16. https://doi.org/10.7314/apjcp.2012.13.12.6011.
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  - Dutta, S. K., K. Agrawal, and M. A. Mahmoud. “Modulation of salivation and heartburn in response to the site of acid infusion in the human oesophagus.” Aliment Pharmacol Ther 32, no. 6 (September 2010): 795–800. https://doi.org/10.1111/j.1365-2036.2010.04397.x.
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  - Sands, B. E., R. Kozarek, J. Spainhour, C. F. Barish, S. Becker, L. Goldberg, S. Katz, et al. “Safety and tolerability of concurrent natalizumab treatment for patients with Crohn's disease not in remission while receiving infliximab.” Ibdjournal 13, no. 1 (December 19, 2006): 2–11. https://doi.org/10.1002/ibd.20014.
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  - Grady, T., M. Mah’Moud, T. Otani, S. Rhee, M. M. Lerch, and F. S. Gorelick. “Zymogen proteolysis within the pancreatic acinar cell is associated with cellular injury.” Am J Physiol 275, no. 5 (November 1998): G1010–17. https://doi.org/10.1152/ajpgi.1998.275.5.G1010.
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- Conference Papers
  - Alam, Imtiaz, Kimberley Brown, Cynthia Donovan, Jamie Forlenza, Kris Lauwers, Mitchell A. Mah’moud, Richard A. Manch, et al. “Su1426 Effectiveness of Simeprevir-Containing Regimens Among Patients With Chronic Hepatitis C Virus in Various US Practice Settings: The SONET Study.” In Gastroenterology, 150:S1096–97. Elsevier BV, 2016. https://doi.org/10.1016/s0016-5085(16)33703-9.
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  - Anderson, Mark, Mitchell Mahʼmoud, Gerald Klein, Raymond M. Panas, Hayley Young, and Bruce Burnett. “Management of Small Intestinal Bacterial Overgrowth, (SIBO) Through Dietary and Nutritional Intervention.” In American Journal of Gastroenterology, 110:S997–S997. Ovid Technologies (Wolters Kluwer Health), 2015. https://doi.org/10.14309/00000434-201510001-02402.
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  - Anderson, Mark, Mitchell Mahʼmoud, and Hayley Young. “Use of Serum-Derived Bovine Immunoglobulin/Protein Isolate (SBI) for the Management of DMARD-Induced Chronic Loose and Frequent Stools.” In American Journal of Gastroenterology, 110:S285–S285. Ovid Technologies (Wolters Kluwer Health), 2015. https://doi.org/10.14309/00000434-201510001-00642.
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  - Salt, William, Fred Fowler, Mitchell Mahʼmoud, Hayley Young, and Raymond M. Panas. “Serum-Derived Bovine Immunoglobulin/Protein Isolate (SBI) Provides Management for Patients With Longstanding Intractable Diarrhea.” In American Journal of Gastroenterology, 110:S285–S285. Ovid Technologies (Wolters Kluwer Health), 2015. https://doi.org/10.14309/00000434-201510001-00643.
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  - Di Bisceglie, Adrian M., Alexander Kuo, Vinod K. Rustgi, Mark S. Sulkowski, Richard K. Sterling, Thomas Stewart, Michael W. Fried, et al. “Virologic Outcomes and Adherence to Treatment Algorithms in a Longitudinal Study of Patients with Chronic Hepatitis C Treated with Boceprevir (BOC) or Telaprevir (TVR) in the United States (HCV-TARGET).” In Hepatology, 58:227A-228A. WILEY-BLACKWELL, 2013.
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  - Mahʼmoud, Mitchell, Mark Anderson, Robert Schellenberg, and Michelle Beckham. “A Rare Cause of Melena Due to Acute Upper Gastrointestinal Bleeding.” In American Journal of Gastroenterology, 107:S356–S356. Ovid Technologies (Wolters Kluwer Health), 2012. https://doi.org/10.14309/00000434-201210001-00867.
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  - Mahʼmoud, Mitchell. “Hepatitis C Recurrence after Sustained Virologic Response.” In American Journal of Gastroenterology, 106:S307–S307. Ovid Technologies (Wolters Kluwer Health), 2011. https://doi.org/10.14309/00000434-201110002-00822.
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  - Dutta, Sudhir K., Kireet Agrawal, and Mitchell Mah’moud. “Modulation of Salivation and Heartburn in Response to the Site of Acid Infusion in Human Esophagus.” In Gastroenterology, 136:A427–A427. W B SAUNDERS CO-ELSEVIER INC, 2009.
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  - Kugelmas, Marcelo, and Mitchell A. Mah’moud. “DO GROWTH FACTORS IMPROVE SVR IN CHRONIC HCV-GENOTYPE 1 PATIENTS TREATED WITH PEG-INTERFERON AND RIBAVIRIN?” In Hepatology, 48:402A-402A. JOHN WILEY & SONS INC, 2008.
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  - Mahʼmoud, Mitchell, Mark Anderson, Robert Schellenberg, and Allison Taylor. “An Unusual Cause of Portal Hypertensive Variceal Bleeding in a Young Adult Female.” In American Journal of Gastroenterology, 103:S371–S371. Ovid Technologies (Wolters Kluwer Health), 2008. https://doi.org/10.14309/00000434-200809001-00944.
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  - Kugelmas, Marcelo, Olga Ryan, Gary A. Spiegelman, and Mitchell Mah’moud. “Do growth factors improve evr in chronic HCV-genotype 1 patients treated with PEG-Intron and ribavirin?” In Gastroenterology, 132:A780–A780. W B SAUNDERS CO-ELSEVIER INC, 2007.
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  - Bini, E. J., B. S. Anand, A. Aytaman, A. Samanta, I. Cordoba-Rellosa, B. Nemchausky, H. H. Trevino, et al. “Glucose-6-phosphate dehydrogenase deficiency is associated with severe anemia during interferon and ribavirin therapy.” In Hepatology, 42:648A-648A. JOHN WILEY & SONS INC, 2005.
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  - Mahʼmoud, Mitchell A., Mark W. Anderson, Camilla Proctor, Sandra Giles, Pameula Johnson, Amy Camp, Kelly Nichols, and William Pittman. “A Case of Acute Colonic Ischemia Due to Routine Diagnostic Colonoscopy.” In American Journal of Gastroenterology, 100:S267–68. Ovid Technologies (Wolters Kluwer Health), 2005. https://doi.org/10.14309/00000434-200509001-00715.
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  - Mahʼmoud, Mitchell A., Robert K. Schellenberg, Donald Rabil, Melissa A. Muovich, Lue Fortney, Kelly Nichols, and Mark Pate. “An Unusual Cause of Cyanosis Associated with Esophagogastroduodenoscopy (EGD) in an Healthy Female.” In American Journal of Gastroenterology, 100:S268–S268. Ovid Technologies (Wolters Kluwer Health), 2005. https://doi.org/10.14309/00000434-200509001-00716.
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  - Bini, E. J., A. Aytaman, B. S. Anand, A. Samanta, B. Nemchausky, H. H. Trevino, M. A. Mah’moud, et al. “Randomized comparison of daily interferon alfa-2b and ribavirin for 24 weeks versus standard combination therapy for 48 weeks in veterans with chronic hepatitis C: Final results of a va multicenter study.” In Hepatology, 36:581A-581A. W B SAUNDERS CO, 2002.
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  - Mah’moud, M. A., S. Karne, and F. S. Gorelick. “Alcohol potentiates the cell injury response induced by cholecystokin in isolated rat pancreatic acini.” In Gastroenterology, 116:A1146–A1146. W B SAUNDERS CO-ELSEVIER INC, 1999.
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  - Schaberg, J. W., S. K. Chockalingam, M. A. Mah’moud, J. Moloo, E. A. Ugheoke, and R. Vasudeva. “The impact of a formulary change in proton pump inhibitor(PPI)as maintenance treatment for gastroesophageal reflux disease(GERD).” In Gastroenterology, 116:A93–A93. W B SAUNDERS CO-ELSEVIER INC, 1999.
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Teaching & Mentoring
Advising & Mentoring
- I have been a mentor of the AASLD Fellow/Mentee Program since 2915 where I have been advising graduating Advanced Hepatology Fellows about academic careers and research opportunities.
  In addition, I have been mentoring several fellows during and after their graduation from Duke GI Fellowship program.
Teaching Activities
- I have been involved in teaching the Duke GI Fellows at the weekly Liver Pathology Conference and Hepatology Case Conference since 2008
Scholarly, Clinical, & Service Activities
Presentations & Appearances
Outreach & Engaged Scholarship
Service to the Profession
Service to Duke
Clinical Activities
- Inpatient and Outpatient Hepatology and General GI services

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Education, Training, & Certifications

Medical Licensure

Previous Appointments & Affiliations

Academic Positions Outside Duke

Awards & Honors

Global Scholarship

Teaching

Fellowships, Supported Research, & Other Grants

Selected Publications

Academic Articles

Conference Papers

Advising & Mentoring

Teaching Activities

Presentations & Appearances

Outreach & Engaged Scholarship

Service to the Profession

Service to Duke

Clinical Activities