Mohamad Abdul Mikati

Wilburt C. Davison Distinguished Professor

Pediatrics, Neurology

mohamad.mikati@duke.edu

Box 3936 Med Ctr, Durham, NC 27710

315 Trent Drive, Hanes House, Suite 345, Durham, NC 27710

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Scholarly Works - Conferences

Abstract 4135211: Children with the D801N Variant of the ATP1A3- Encoded Sodium-Potassium ATPase Alpha-3 Subunit Demonstrate Paradoxical QT Response to Bradycardia and Increased Ventricular Arrhythmia Risk

Conference Circulation · November 12, 2024 Introduction: Alternating hemiplegia of childhood (AHC) is a rare condition most frequently caused by mutations in ATP1A3, encoding for ... Full text Cite

Detrimental effects of anticholinergic therapy in an ATP1A3-mutation mouse model of sudden unexpected death in epilepsy

Conference EPILEPSIA · November 2024 Link to item Cite

Cardiorespiratory rate down-regulation occurs immediately before and not just during terminal seizures in the Na⁺/K⁺-ATPase sudden unexpected death in epilepsy (SUDEP) model

Conference EPILEPSIA · November 2023 Link to item Cite

Development and evaluation of the usefulness of an electronic diary (e-Diary) for the recording of seizures and other paroxysmal events in alternating hemiplegia of childhood (AHC)

Conference EPILEPSIA · November 2023 Link to item Cite

Inhibition of the Sodium Potassium ATPase Alpha 3 (ATP1A3) Pump Function Alters Repolarization Time and is Proarrhythmic in Cardiac Myocytes

Conference CIRCULATION · November 8, 2022 Link to item Cite

UMBILICAL CORD BLOOD AND CORD TISSUE MESENCHYMAL STROMAL CELLS IN CHILDREN WITH CEREBRAL PALSY

Conference CYTOTHERAPY · May 2021 Link to item Cite

De novo variants in SNAP25 cause an early-onset developmental and epileptic encephalopathy.

Conference Genet Med · April 2021 PURPOSE: This study aims to provide a comprehensive description of the phenotypic and genotypic spectrum of SNAP25 developmental and epileptic encephalopathy (SNAP25-DEE) by reviewing newly identified and previously reported individuals. METHODS: Individua ... Full text Link to item Cite

Cardiac Phenotype In ATP1A3 Related-Syndromes: A Multicentre Study

Conference EPILEPSIA · November 2019 Link to item Cite

Delayed Time to EEG Placement is Associated with Longer Seizure Duration in Refractory Pediatric Status Epilepticus (the pSERG Cohort)

Conference ANNALS OF NEUROLOGY · October 2019 Link to item Cite

De novo missense variants in RHOBTB2 cause a developmental and epileptic encephalopathy in humans, and altered levels cause neurological defects in Drosophila

Conference EUROPEAN JOURNAL OF HUMAN GENETICS · July 1, 2019 Link to item Cite

Neuropsychological Assessment In Patients with Alternating Hemiplegia Of Childhood (AHC)

Conference NEUROLOGY · April 9, 2019 Link to item Cite

Novel Phenotype of ATP1A3 Mutation Starting in Infancy

Conference NEUROLOGY · April 10, 2018 Link to item Cite

CEREBELLAR PURKINJE CELL COUNTS IN A KNOCK-IN MOUSE MODEL OF ALTERNATING HEMIPLEGIA OF CHILDHOOD

Conference EPILEPSIA · December 1, 2017 Link to item Cite

Novel Clinical Presentations and Characteristics in Patients with KCNA2 Mutations

Conference NEUROLOGY · April 18, 2017 Link to item Cite

D-DEMO, A Novel and Distinct Phenotype Caused by ATP1A3 Mutations

Conference NEUROLOGY · April 18, 2017 Link to item Cite

A Case of GLUT1 Deficiency Associated Episodic Ataxia Without Epilepsy

Conference NEUROLOGY · April 18, 2017 Link to item Cite

Status Epilepticus in Children: Relationship between Pre-Hospital Treatment and Outcome

Conference NEUROLOGY · April 5, 2016 Link to item Cite

Status Epilepticus in Children: Relationship between Pre-Hospital Treatment and Outcome

Conference NEUROLOGY · April 5, 2016 Link to item Cite

Novel Knock-in Mouse Model of Genetic Atp1a3 Dysfunction

Conference NEUROLOGY · April 5, 2016 Link to item Cite

Effects of Vagal Nerve Stimulation in Alternating Hemiplegia of Childhood

Conference NEUROLOGY · April 5, 2016 Link to item Cite

Adequately Dosed Autologous Cord Blood Infusion Is Associated with Motor Improvement in Children with Cerebral Palsy

Conference Biology of Blood and Marrow Transplantation · March 2016 Full text Cite

Autologous Cord Blood Infusion for the Treatment of Brain Injury in Children with Cerebral Palsy

Conference BLOOD · December 3, 2015 Link to item Cite

Single Otherwise Asymptomatic Mutation Modifies Long-Term Outcome after Mild Perinatal Hypoxia by Resulting Spontaneous Recurrent Seizures without Affecting the Severity of Acute Hypoxic Seizures

Conference ANNALS OF NEUROLOGY · October 1, 2013 Link to item Cite

Clinical Characteristics and Treatment Strategies in Refractory Convulsive Status Epilepticus in Children: Results from the Pediatric Status Epilepticus Research Group (pSERG)

Conference NEUROLOGY · February 12, 2013 Link to item Cite

Diffusion Tensor Imaging Uncovers Otherwise-Unrecognized Abnormalities in Frontal Lobe Cortex in Children with Intractable Frontal Lobe as Well as Temporal Lobe Epilepsy

Conference NEUROLOGY · April 2012 Link to item Cite

ATP1A3 De Novo Mutations in Alternating Hemiplegia of Childhood

Conference ANNALS OF NEUROLOGY · January 1, 2012 Link to item Cite

EEG and seizure characteristics in patients with primary cerebral folate deficiency

Conference ANNALS OF NEUROLOGY · October 1, 2011 Link to item Cite

Diffusion tensor imaging abnormalities in frontal cortex in drug resistant pediatric partial epilepsy

Conference ANNALS OF NEUROLOGY · October 1, 2011 Link to item Cite

Cost-benefit analysis of early childhood development intervention programs

Conference ANNALS OF NEUROLOGY · October 1, 2011 Link to item Cite

Hemispherectomy for Intractable Epilepsy in Children: Experience with Novel Complications

Conference NEUROLOGY · March 1, 2011 Link to item Cite

Impairment in social and physical domains but not in emotional or school performance domains of quality of life in mentally retarded children in Lebanon

Conference NEUROLOGY · March 11, 2008 Link to item Cite

Changes in hippocampal connexin 30, 36, and 43 expression after acute hypoxia in the developing brain

Conference NEUROLOGY · March 11, 2008 Link to item Cite

Perinatal hypoxia induces type I but not type II apoptosis in rat pups

Conference ANNALS OF NEUROLOGY · January 1, 2008 Link to item Cite

Acute hypoxia results in changes in hippocampal connexin expression in the developing brain

Conference ANNALS OF NEUROLOGY · January 1, 2008 Link to item Cite

Potential protective effect of a single dose of quinine given after a hypoxic insult in P10 rat pups

Conference ANNALS OF NEUROLOGY · January 1, 2008 Link to item Cite

Differential age dependent vulnerability to acute hypoxia in BALB/c mice

Conference ANNALS OF NEUROLOGY · January 1, 2008 Link to item Cite

The effect of stereotaxic C2-ceramide injection on the inositol triphosphate levels in the hippocampus of adult rats

Conference NEUROLOGY · March 14, 2006 Link to item Cite

Lack of ceramide increase in hypoxia-induced apoptosis in the developing brain of neonatal rats

Conference NEUROLOGY · March 14, 2006 Link to item Cite

Seizure type, sex, and age are predictors of positive response to intravenous gamma globulin (IVIG) in intractable epilepsy

Conference NEUROLOGY · March 14, 2006 Link to item Cite

Risk factors for developing subclinical hypothyroidism during valproic acid therapy

Conference NEUROLOGY · March 14, 2006 Link to item Cite

Marked improvements in seizure control and general wellbeing but not in psychosocial or behavioral function after successful epilepsy surgery in children

Conference NEUROLOGY · March 14, 2006 Link to item Cite

Normalization of quality of life (QOL) three years after temporal lobectomy: A controlled study

Conference NEUROLOGY · March 14, 2006 Link to item Cite

Refractory calculation-induced idiopathic generalized epilepsy. A case report and review of the literature

Conference CNS SPECTRUMS · February 1, 2006 Link to item Cite

Predictors of bone mineral density in patients on antiepileptic drugs.

Conference JOURNAL OF BONE AND MINERAL RESEARCH · September 1, 2005 Link to item Cite

Effects of vitamin D therapy on bone density in ambulatory patients on chronic antiepileptic drug therapy: Two randomized trials in children and adults

Conference NEUROLOGY · March 22, 2005 Link to item Cite

Seizure-related programmed cell death

Conference EPILEPSIA · January 1, 2005 Link to item Cite

Topiramate related hyperthermia: A comparative study

Conference EPILEPSIA · January 1, 2005 Link to item Cite

Chronic hypoxic preconditioning accentuates erythropoietin levels and prevents acute hypoxic seizure-associated memory impairment

Conference EPILEPSIA · January 1, 2005 Link to item Cite

Erythropoietin kinetics in plasma and cerebrospinal fluid of adult rats following high-dose recombinant erythropoietin.

Conference EPILEPSIA · January 1, 2005 Link to item Cite