Scholars@Duke
Molly Jean McDonough

Molly Jean McDonough

Assistant Professor of Medicine
Medicine, Infectious Diseases
molly.mcdonough@duke.edu
DUMC Box 102359, Durham, NC 27710
315 Trent Drive Room 356, DUMC Box 102359, Durham, NC 27705

Scholarly Works - Journal articles

Bartonella henselae tricuspid valve endocarditis presenting as fever of unknown origin.

Journal article BMJ Case Rep · February 4, 2026 Cat scratch disease (CSD), caused by Bartonella henselae, is an uncommon cause of fever of unknown origin (FUO) and rarely presents with visceral organ involvement. This case report describes a middle-aged woman with 3 months of night sweats and 1 month of ... Full text Link to item Cite

Scoping review of percutaneous mechanical aspiration for valvular and cardiac implantable electronic device infective endocarditis.

Journal article Clin Microbiol Infect · December 2023 BACKGROUND: Percutaneous mechanical aspiration (PMA) of intravascular vegetations is a novel strategy for management of patients with infective endocarditis (IE) who are at high risk of poor outcomes with conventional cardiac surgery. However, clear indica ... Full text Link to item Cite

The Incidence of Ocular Complications in Candidemic Patients and Implications for the Practice of Routine 
Eye Exams.

Journal article Open Forum Infect Dis · April 2022 BACKGROUND: Ocular candidiasis is a known complication of candidemia. Given the poor ocular penetration of echinocandins, there is some concern that the increasing use of echinocandins may portend an increased incidence of ophthalmic complications. We exam ... Full text Link to item Cite

Xenopus embryos show a compensatory response following perturbation of the Notch signaling pathway.

Journal article Dev Biol · April 15, 2020 As an essential feature of development, robustness ensures that embryos attain a consistent phenotype despite genetic and environmental variation. The growing number of examples demonstrating that embryos can mount a compensatory response to germline mutat ... Full text Link to item Cite

A regression-based differential expression detection algorithm for microarray studies with ultra-low sample size.

Journal article PLoS One · 2015 Global gene expression analysis using microarrays and, more recently, RNA-seq, has allowed investigators to understand biological processes at a system level. However, the identification of differentially expressed genes in experiments with small sample si ... Full text Link to item Cite

Dissection, culture, and analysis of Xenopus laevis embryonic retinal tissue.

Journal article J Vis Exp · December 23, 2012 The process by which the anterior region of the neural plate gives rise to the vertebrate retina continues to be a major focus of both clinical and basic research. In addition to the obvious medical relevance for understanding and treating retinal disease, ... Full text Link to item Cite

Expanding the diversity of mycobacteriophages: insights into genome architecture and evolution.

Journal article PLoS One · January 27, 2011 Mycobacteriophages are viruses that infect mycobacterial hosts such as Mycobacterium smegmatis and Mycobacterium tuberculosis. All mycobacteriophages characterized to date are dsDNA tailed phages, and have either siphoviral or myoviral morphotypes. However ... Full text Link to item Cite

Cluster K mycobacteriophages: insights into the evolutionary origins of mycobacteriophage TM4.

Journal article PLoS One · 2011 Five newly isolated mycobacteriophages--Angelica, CrimD, Adephagia, Anaya, and Pixie--have similar genomic architectures to mycobacteriophage TM4, a previously characterized phage that is widely used in mycobacterial genetics. The nucleotide sequence simil ... Full text Link to item Cite