Nancy Catherine Andrews | Scholars@Duke

Nancy Catherine Andrews
Nanaline H. Duke Professor of Pediatrics

Current Appointments & Affiliations

Nanaline H. Duke Professor of Pediatrics, Pediatrics, Clinical Science Departments 2013
Dean Emerita of the School of Medicine, School of Medicine, Duke University 2007
Professor of Pediatrics, Pediatrics, Clinical Science Departments 2007
Professor of Pharmacology & Cancer Biology, Pharmacology & Cancer Biology, Basic Science Departments 2007
Member of the Duke Cancer Institute, Duke Cancer Institute, Institutes and Centers 2007

Contact Information

DUMC Box 3711, Durham, NC 27710
Nanaline Duke Building Room 255B, Durham, NC 27705
nancy.andrews@duke.edu (919) 681-8876

Background
Education, Training, & Certifications
- M.D., Harvard University 1987
- Ph.D., Massachusetts Institute of Technology 1985
- B.S., Yale University 1980
- M.S., Yale University 1980
Duke Appointment History
- Instructor, Temporary in the Department of Pediatrics, Pediatrics, Clinical Science Departments 2007
Recognition
In the News
- JUL 26, 2016 The News & Observer
  
  Duke medical dean to step down next year
- JUL 22, 2016
  
  School of Medicine Dean Dr. Nancy Andrews to Step Down in 2017
- JUN 26, 2015
  
  Allen Song Named Interim Director of Brain Institute
- APR 29, 2015
  
  Medicine Dean Nancy Andrews Named to National Academy of Sciences
- FEB 26, 2015
  
  Academic Leaders on the Troubled Future of Biomedical Research
- JUN 25, 2014 Fast Company
  
  How the dean of Duke's medical school is breaking down ‘invisible’ gender barriers
- JUN 9, 2014 Durham Herald-Sun
  
  Drs. Nancy Andrews and Edward Buckley: Making sure we have enough doctors
- OCT 22, 2013
  
  Duke Receives $47 Million Award From NIH For Translational Research
- AUG 1, 2013
  
  American Society of Hematology Honors SOM Dean Nancy Andrews
- MAY 2, 2013
  
  National Report Calls for Reorganization of US Scientific Enterprise
Awards & Honors
Research
Selected Grants
- Building Interdisciplinary Research Careers in Women's Health awarded by National Institutes of Health 2002 - 2022
- Bridging the Gap to Enhance Clinical Research Program (BIGGER) awarded by National Institutes of Health 2016 - 2021
- Transfusion Medicine and Hematology awarded by National Institutes of Health 1975 - 2021
- Duke-UNC Clinical Hematology and Transfusion Research Career Development Program awarded by National Institutes of Health 2006 - 2019
- Duke Research Training Program for Pediatricians awarded by National Institutes of Health 2002 - 2018
- Center for Molecular & Cellular Studies of Ped Disease awarded by National Institutes of Health 2003 - 2018
- School of Medicine 2017 Biddle awarded by Mary Duke Biddle Foundation 2017
- NRSA Predoctoral Fellowship awarded by National Institutes of Health 2014 - 2017
- Iron homeostasis in mammalian muscle awarded by National Institutes of Health 2011 - 2016
- Cancer Biology Training Grant awarded by National Cancer Institute 1993 - 2016
- Expansion of Animal Resources for Large Animals (Vivarium Expansion project) awarded by National Institutes of Health 2010 - 2015
- Genes that modify Iron loading in mice awarded by National Institutes of Health 2004 - 2014
- Identification of Novel Genes That Modulate Systemic Iron Homeostasis awarded by National Institutes of Health 2009 - 2013
- Regulation of Iron Homeostasis awarded by National Institutes of Health 1998 - 2010
- Erythroid Iron Transport awarded by National Institutes of Health 2008 - 2009
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Matak, Pavle, Andrija Matak, Sarah Moustafa, Dipendra K. Aryal, Eric J. Benner, William Wetsel, and Nancy C. Andrews. “Disrupted iron homeostasis causes dopaminergic neurodegeneration in mice..” Proceedings of the National Academy of Sciences of the United States of America 113, no. 13 (March 2016): 3428–35. https://doi.org/10.1073/pnas.1519473113.
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  - Jabara, Haifa H., Steven E. Boyden, Janet Chou, Narayanaswamy Ramesh, Michel J. Massaad, Halli Benson, Wayne Bainter, et al. “A missense mutation in TFRC, encoding transferrin receptor 1, causes combined immunodeficiency..” Nat Genet 48, no. 1 (January 2016): 74–78. https://doi.org/10.1038/ng.3465.
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  - Barrientos, Tomasa, Indira Laothamatas, Timothy R. Koves, Erik J. Soderblom, Miles Bryan, M Arthur Moseley, Deborah M. Muoio, and Nancy C. Andrews. “Metabolic Catastrophe in Mice Lacking Transferrin Receptor in Muscle..” Ebiomedicine 2, no. 11 (November 2015): 1705–17. https://doi.org/10.1016/j.ebiom.2015.09.041.
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  - Xu, Wenjing, Tomasa Barrientos, Lan Mao, Howard A. Rockman, Anthony A. Sauve, and Nancy C. Andrews. “Lethal Cardiomyopathy in Mice Lacking Transferrin Receptor in the Heart..” Cell Reports 13, no. 3 (October 8, 2015): 533–45. https://doi.org/10.1016/j.celrep.2015.09.023.
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  - Andrews, Nancy C. “Hungry irony..” The Journal of Clinical Investigation 125, no. 9 (September 2015): 3422–23. https://doi.org/10.1172/JCI83193.
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  - Chen, Alan C., Adriana Donovan, Renee Ned-Sykes, and Nancy C. Andrews. “Noncanonical role of transferrin receptor 1 is essential for intestinal homeostasis..” Proceedings of the National Academy of Sciences of the United States of America 112, no. 37 (September 2015): 11714–19. https://doi.org/10.1073/pnas.1511701112.
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  - “Women in metabolism: part I..” Cell Metab 21, no. 5 (May 5, 2015): 654–57.
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  - Levine, Arthur S., Robert J. Alpern, Nancy C. Andrews, Karen Antman, Jeffrey R. Balser, Jeremy M. Berg, Pamela B. Davis, et al. “Research in academic medical centers: two threats to sustainable support..” Science Translational Medicine 7, no. 289 (May 2015). https://doi.org/10.1126/scitranslmed.aac5200.
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  - Chen, Alan, Renee M. Ned, Adriana Donovan, and Nancy C. Andrews. “INACTIVATION OF TRANSFERRIN RECEPTOR (TFR1) IN THE PANCREAS RESULTS IN PANCREATITIS AND DIABETES.” American Journal of Hematology 88, no. 5 (May 1, 2013): E197–E197.
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  - Chen, Alan, Renee M. Ned, Adriana Donovan, and Nancy C. Andrews. “TRANSFERRIN RECEPTOR 1 (TFR1) IS REQUIRED FOR MAINTENANCE OF THE INTESTINAL EPITHELIUM.” American Journal of Hematology 88, no. 5 (May 1, 2013): E12–13.
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  - Xu, Wenjing, Tomasa Barrientos, and Nancy C. Andrews. “Iron and copper in mitochondrial diseases..” Cell Metab 17, no. 3 (March 5, 2013): 319–28. https://doi.org/10.1016/j.cmet.2013.02.004.
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  - Andrews, N. C., and V. N. Murti. “On soloists, symphonies, and transdisciplinary research.” Issues in Science and Technology 30, no. 1 (January 1, 2013): 30–32.
  - Prince, Olivier D., Jacqueline M. Langdon, Andrew J. Layman, Ian C. Prince, Miguel Sabogal, Howard H. Mak, Alan E. Berger, et al. “Late stage erythroid precursor production is impaired in mice with chronic inflammation..” Haematologica 97, no. 11 (November 2012): 1648–56. https://doi.org/10.3324/haematol.2011.053397.
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  - Hansen, Jakob Bondo, Morten Fog Tonnesen, Andreas Nygaard Madsen, Peter H. Hagedorn, Josefine Friberg, Lars Groth Grunnet, R Scott Heller, et al. “Divalent metal transporter 1 regulates iron-mediated ROS and pancreatic β cell fate in response to cytokines..” Cell Metabolism 16, no. 4 (October 2012): 449–61. https://doi.org/10.1016/j.cmet.2012.09.001.
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  - Roberts, Kristina A., Victoria E. Abraira, Andrew F. Tucker, Lisa V. Goodrich, and Nancy C. Andrews. “Mutation of Rubie, a novel long non-coding RNA located upstream of Bmp4, causes vestibular malformation in mice..” Plos One 7, no. 1 (January 12, 2012). https://doi.org/10.1371/journal.pone.0029495.
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  - Andrews, Nancy C. “Closing the iron gate..” The New England Journal of Medicine 366, no. 4 (January 2012): 376–77. https://doi.org/10.1056/nejmcibr1112780.
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  - Jin, Jie, Long-Jun Wu, Janice Jun, Xiping Cheng, Haoxing Xu, Nancy C. Andrews, and David E. Clapham. “The channel kinase, TRPM7, is required for early embryonic development..” Proceedings of the National Academy of Sciences of the United States of America 109, no. 5 (January 2012): E225–33. https://doi.org/10.1073/pnas.1120033109.
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  - Andrews, N. C. “Personalized medicine to anticipatory health.” Journal of Surgical Radiology 2, no. 3 (December 1, 2011): 220–23.
  - Andrews, Nancy C. “An iron-clad role for proteasomal degradation..” Cell Metabolism 14, no. 3 (September 2011): 281–82. https://doi.org/10.1016/j.cmet.2011.08.001.
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  - Chen, Wenjie, Franklin W. Huang, Tomasa Barrientos de Renshaw, and Nancy C. Andrews. “Skeletal muscle hemojuvelin is dispensable for systemic iron homeostasis..” Blood 117, no. 23 (June 2011): 6319–25. https://doi.org/10.1182/blood-2010-12-327957.
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  - Finberg, Karin E., Rebecca L. Whittlesey, and Nancy C. Andrews. “Tmprss6 is a genetic modifier of the Hfe-hemochromatosis phenotype in mice..” Blood 117, no. 17 (April 2011): 4590–99. https://doi.org/10.1182/blood-2010-10-315507.
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  - Bartnikas, Thomas B., Nancy C. Andrews, and Mark D. Fleming. “Transferrin is a major determinant of hepcidin expression in hypotransferrinemic mice..” Blood 117, no. 2 (January 2011): 630–37. https://doi.org/10.1182/blood-2010-05-287359.
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  - Schmidt, P. J., N. C. Andrews, and M. D. Fleming. “Hepcidin induction by transgenic overexpression of Hfe does not require the Hfe cytoplasmic tail, but does require hemojuvelin.” Blood 116, no. 25 (December 16, 2010): 5679–87. https://doi.org/10.1182/blood-2010-04-277954.
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  - Gardenghi, Sara, Pedro Ramos, Maria Franca Marongiu, Luca Melchiori, Laura Breda, Ella Guy, Kristen Muirhead, et al. “Hepcidin as a therapeutic tool to limit iron overload and improve anemia in β-thalassemic mice..” The Journal of Clinical Investigation 120, no. 12 (December 2010): 4466–77. https://doi.org/10.1172/JCI41717.
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  - Schmidt, Paul J., Nancy C. Andrews, and Mark D. Fleming. “Hepcidin induction by transgenic overexpression of Hfe does not require the Hfe cytoplasmic tail, but does require hemojuvelin..” Blood 116, no. 25 (December 2010): 5679–87. https://doi.org/10.1182/blood-2010-04-277954.
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  - Andrews, Nancy C. “Ferrit(in)ing out new mechanisms in iron homeostasis..” Cell Metabolism 12, no. 3 (September 2010): 203–4. https://doi.org/10.1016/j.cmet.2010.08.011.
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  - Ferrucci, Luigi, Richard D. Semba, Jack M. Guralnik, William B. Ershler, Stefania Bandinelli, Kushang V. Patel, Kai Sun, et al. “Proinflammatory state, hepcidin, and anemia in older persons..” Blood 115, no. 18 (May 6, 2010): 3810–16. https://doi.org/10.1182/blood-2009-02-201087.
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  - Finberg, Karin E., Rebecca L. Whittlesey, Mark D. Fleming, and Nancy C. Andrews. “Down-regulation of Bmp/Smad signaling by Tmprss6 is required for maintenance of systemic iron homeostasis..” Blood 115, no. 18 (May 2010): 3817–26. https://doi.org/10.1182/blood-2009-05-224808.
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  - Cheng, Xiping, Jie Jin, Lily Hu, Dongbiao Shen, Xian-Ping Dong, Mohammad A. Samie, Jayne Knoff, et al. “TRP channel regulates EGFR signaling in hair morphogenesis and skin barrier formation..” Cell 141, no. 2 (April 16, 2010): 331–43. https://doi.org/10.1016/j.cell.2010.03.013.
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  - Andrews, N. C., and T. Ganz. “The Molecular Basis of Iron Metabolism,” March 10, 2010, 169–78. https://doi.org/10.1002/9781444318531.ch14.
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  - Andrews, Nancy C., Sally Kornbluth, and Doug Stokke. “Women: diversity among leaders is there if you look..” Nature 463, no. 7281 (February 2010). https://doi.org/10.1038/463608d.
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  - Andrews, Nancy C. “Can we keep the "academic" in academic medicine? 2009 American Society for Clinical Investigation Presidential Address..” The Journal of Clinical Investigation 120, no. 1 (January 2010): 390–93. https://doi.org/10.1172/JCI41934.
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  - Andrews, Nancy C. “Genes determining blood cell traits..” Nature Genetics 41, no. 11 (November 2009): 1161–62. https://doi.org/10.1038/ng1109-1161.
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  - Andrews, Nancy C. “Build it and hope that enough of them will come..” The Journal of Clinical Investigation 119, no. 10 (October 2009): 2860–61. https://doi.org/10.1172/JCI41105.
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  - Andrews, Nancy C. “ABCs of erythroid mitochondrial iron uptake..” Proceedings of the National Academy of Sciences of the United States of America 106, no. 38 (September 15, 2009): 16012–13. https://doi.org/10.1073/pnas.0909137106.
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  - Carlson, Erik S., Ivan Tkac, Rhamy Magid, Michael B. O’Connor, Nancy C. Andrews, Timothy Schallert, Hiromi Gunshin, Michael K. Georgieff, and Anna Petryk. “Iron is essential for neuron development and memory function in mouse hippocampus..” J Nutr 139, no. 4 (April 2009): 672–79. https://doi.org/10.3945/jn.108.096354.
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  - Li, Jau Yi, Neal Paragas, Renee M. Ned, Andong Qiu, Melanie Viltard, Thomas Leete, Ian R. Drexler, et al. “Scara5 is a ferritin receptor mediating non-transferrin iron delivery..” Dev Cell 16, no. 1 (January 2009): 35–46. https://doi.org/10.1016/j.devcel.2008.12.002.
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  - Gardenghi, Sara, Maria Franca Marongiu, Kristen Muirhead, P. Ramos, Cindy N. Roy, Nancy C. Andrews, Elizabeta Nemeth, et al. “Increased Hepcidin Expression in Mice Affected by beta-Thalassemia Reduces Iron Overload with No Effect on Anemia.” Blood 112, no. 11 (November 16, 2008): 53–53.
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  - Jin, Jie, Bimal N. Desai, Betsy Navarro, Adriana Donovan, Nancy C. Andrews, and David E. Clapham. “Deletion of Trpm7 disrupts embryonic development and thymopoiesis without altering Mg2+ homeostasis..” Science 322, no. 5902 (October 31, 2008): 756–60. https://doi.org/10.1126/science.1163493.
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  - Andrews, Nancy. “The science of climbing the academic ladder. Interview by Barbara Kantrowitz and Holly Peterson..” Newsweek 152, no. 15 (October 2008).
  - Zhu, Bing-Mei, Sara K. McLaughlin, Risu Na, Jie Liu, Yongzhi Cui, Cyril Martin, Akiko Kimura, Gertraud W. Robinson, Nancy C. Andrews, and Lothar Hennighausen. “Hematopoietic-specific Stat5-null mice display microcytic hypochromic anemia associated with reduced transferrin receptor gene expression..” Blood 112, no. 5 (September 2008): 2071–80. https://doi.org/10.1182/blood-2007-12-127480.
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  - Andrews, Nancy C. “Forging a field: the golden age of iron biology..” Blood 112, no. 2 (July 15, 2008): 219–30. https://doi.org/10.1182/blood-2007-12-077388.
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  - Finberg, Karin E., Matthew M. Heeney, Dean R. Campagna, Yeşim Aydinok, Howard A. Pearson, Kip R. Hartman, Mary M. Mayo, et al. “Mutations in TMPRSS6 cause iron-refractory iron deficiency anemia (IRIDA)..” Nat Genet 40, no. 5 (May 2008): 569–71. https://doi.org/10.1038/ng.130.
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  - Liu, Sijin, Rajasekhar N. V. S. Suragani, Anping Han, Wanting Zhao, Nancy C. Andrews, and Jane-Jane Chen. “Deficiency of heme-regulated eIF2alpha kinase decreases hepcidin expression and splenic iron in HFE-/- mice..” Haematologica 93, no. 5 (May 2008): 753–56. https://doi.org/10.3324/haematol.12175.
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  - Schmidt, Paul J., Paul T. Toran, Anthony M. Giannetti, Pamela J. Bjorkman, and Nancy C. Andrews. “The transferrin receptor modulates Hfe-dependent regulation of hepcidin expression..” Cell Metabolism 7, no. 3 (March 2008): 205–14. https://doi.org/10.1016/j.cmet.2007.11.016.
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  - Wrighting, Diedra M., and Nancy C. Andrews. “Iron homeostasis and erythropoiesis..” Current Topics in Developmental Biology 82 (January 2008): 141–67. https://doi.org/10.1016/s0070-2153(07)00006-3.
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  - Andrews, Nancy C. “Climbing through medicine's glass ceiling..” The New England Journal of Medicine 357, no. 19 (November 2007): 1887–89. https://doi.org/10.1056/nejmp078198.
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  - Liu, Sijin, Rajasekhar N. V. S. Suragani, Fudi Wang, Anping Han, Wanting Zhao, Nancy C. Andrews, and Jane-Jane Chen. “The function of heme-regulated eIF2alpha kinase in murine iron homeostasis and macrophage maturation..” The Journal of Clinical Investigation 117, no. 11 (November 2007): 3296–3305. https://doi.org/10.1172/JCI32084.
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  - Wang, Fudi, Adam P. Lothrop, Nicholas G. James, Tanya A. M. Griffiths, Lisa A. Lambert, Rachael Leverence, Igor A. Kaltashov, Nancy C. Andrews, Ross T. A. MacGillivray, and Anne B. Mason. “A novel murine protein with no effect on iron homoeostasis is homologous with transferrin and is the putative inhibitor of carbonic anhydrase..” The Biochemical Journal 406, no. 1 (August 2007): 85–95. https://doi.org/10.1042/BJ20070384.
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  - Wang, Fudi, Prasad N. Paradkar, Angel O. Custodio, Diane McVey Ward, Mark D. Fleming, Dean Campagna, Kristina A. Roberts, et al. “Genetic variation in Mon1a affects protein trafficking and modifies macrophage iron loading in mice..” Nature Genetics 39, no. 8 (August 2007): 1025–32. https://doi.org/10.1038/ng2059.
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  - Babitt, Jodie L., Franklin W. Huang, Yin Xia, Yisrael Sidis, Nancy C. Andrews, and Herbert Y. Lin. “Modulation of bone morphogenetic protein signaling in vivo regulates systemic iron balance..” The Journal of Clinical Investigation 117, no. 7 (July 2007): 1933–39. https://doi.org/10.1172/JCI31342.
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  - Gardenghi, Sara, Maria F. Marongiu, Pedro Ramos, Ella Guy, Laura Breda, Amy Chadburn, YiFang Liu, et al. “Ineffective erythropoiesis in beta-thalassemia is characterized by increased iron absorption mediated by down-regulation of hepcidin and up-regulation of ferroportin..” Blood 109, no. 11 (June 2007): 5027–35. https://doi.org/10.1182/blood-2006-09-048868.
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  - Andrews, N. C. “Of mice and iron: Ferroportin disease.” Blood 109, no. 10 (May 15, 2007). https://doi.org/10.1182/blood-2007-02-075739.
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  - Roy, Cindy N., Howard H. Mak, Imo Akpan, Grigoriy Losyev, David Zurakowski, and Nancy C. Andrews. “Hepcidin antimicrobial peptide transgenic mice exhibit features of the anemia of inflammation..” Blood 109, no. 9 (May 2007): 4038–44. https://doi.org/10.1182/blood-2006-10-051755.
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  - Radoshitzky, Sheli R., Jonathan Abraham, Christina F. Spiropoulou, Jens H. Kuhn, Dan Nguyen, Wenhui Li, Jane Nagel, et al. “Transferrin receptor 1 is a cellular receptor for New World haemorrhagic fever arenaviruses..” Nature 446, no. 7131 (March 2007): 92–96. https://doi.org/10.1038/nature05539.
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  - Andrews, Nancy C. “When is a heme transporter not a heme transporter? When it's a folate transporter..” Cell Metabolism 5, no. 1 (January 2007): 5–6. https://doi.org/10.1016/j.cmet.2006.12.004.
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  - Andrews, Nancy C., and Paul J. Schmidt. “Iron homeostasis..” Annual Review of Physiology 69 (January 2007): 69–85. https://doi.org/10.1146/annurev.physiol.69.031905.164337.
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  - Andrews, N. C. “Iron metabolism,” December 1, 2006, 848–53. https://doi.org/10.1007/978-1-59259-963-9_87.
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  - Andrews, N. C. “Iron Absorption” 2 (December 1, 2006): 1983–92. https://doi.org/10.1016/B978-012088394-3/50081-7.
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  - Wrighting, Diedra M., and Nancy C. Andrews. “Interleukin-6 induces hepcidin expression through STAT3..” Blood 108, no. 9 (November 2006): 3204–9. https://doi.org/10.1182/blood-2006-06-027631.
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  - Goswami, Tapasree, and Nancy C. Andrews. “Hereditary hemochromatosis protein, HFE, interaction with transferrin receptor 2 suggests a molecular mechanism for mammalian iron sensing..” The Journal of Biological Chemistry 281, no. 39 (September 2006): 28494–98. https://doi.org/10.1074/jbc.c600197200.
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  - Babitt, Jodie L., Franklin W. Huang, Diedra M. Wrighting, Yin Xia, Yisrael Sidis, Tarek A. Samad, Jason A. Campagna, et al. “Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression..” Nature Genetics 38, no. 5 (May 2006): 531–39. https://doi.org/10.1038/ng1777.
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  - Donovan, Adriana, Cindy N. Roy, and Nancy C. Andrews. “The ins and outs of iron homeostasis..” Physiology (Bethesda, Md.) 21 (April 2006): 115–23. https://doi.org/10.1152/physiol.00052.2005.
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  - Viatte, Lydie, Gaël Nicolas, Dan-Qing Lou, Myriam Bennoun, Jeanne-Claire Lesbordes-Brion, François Canonne-Hergaux, Kai Schönig, et al. “Chronic hepcidin induction causes hyposideremia and alters the pattern of cellular iron accumulation in hemochromatotic mice..” Blood 107, no. 7 (April 2006): 2952–58. https://doi.org/10.1182/blood-2005-10-4071.
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  - Adams, Brian D., Rossitza Lazova, Nancy C. Andrews, and Leonard M. Milstone. “Iron in skin of mice with three etiologies of systemic iron overload..” The Journal of Investigative Dermatology 125, no. 6 (December 2005): 1200–1205. https://doi.org/10.1111/j.0022-202X.2005.23949.x.
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  - Andrews, Nancy C. “Understanding heme transport..” The New England Journal of Medicine 353, no. 23 (December 2005): 2508–9. https://doi.org/10.1056/nejmcibr053987.
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  - Frazer, David M., Sarah J. Wilkins, Christopher D. Vulpe, and Gregory J. Anderson. “The role of duodenal cytochrome b in intestinal iron absorption remains unclear..” Blood 106, no. 13 (December 2005). https://doi.org/10.1182/blood-2005-07-2923.
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  - Lim, Jackie E., Ou Jin, Carolyn Bennett, Kelly Morgan, Fudi Wang, Cameron C. Trenor, Mark D. Fleming, and Nancy C. Andrews. “A mutation in Sec15l1 causes anemia in hemoglobin deficit (hbd) mice..” Nature Genetics 37, no. 11 (November 2005): 1270–73. https://doi.org/10.1038/ng1659.
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  - Gunshin, Hiromi, Carolyn N. Starr, Cristina Direnzo, Mark D. Fleming, Jie Jin, Eric L. Greer, Vera M. Sellers, Stephanie M. Galica, and Nancy C. Andrews. “Cybrd1 (duodenal cytochrome b) is not necessary for dietary iron absorption in mice..” Blood 106, no. 8 (October 2005): 2879–83. https://doi.org/10.1182/blood-2005-02-0716.
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  - Gunshin, Hiromi, Jie Jin, Yuko Fujiwara, Nancy C. Andrews, Martha Mims, and Josef Prchal. “Analysis of the E399D mutation in SLC11A2..” Blood 106, no. 6 (September 2005). https://doi.org/10.1182/blood-2005-03-1192.
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  - Huang, Franklin W., Jack L. Pinkus, Geraldine S. Pinkus, Mark D. Fleming, and Nancy C. Andrews. “A mouse model of juvenile hemochromatosis..” The Journal of Clinical Investigation 115, no. 8 (August 2005): 2187–91. https://doi.org/10.1172/JCI25049.
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  - Andrews, Nancy C., Sudha Anupindi, and Kamran Badizadegan. “Case records of the Massachusetts General Hospital. Case 21-2005. A four-week-old male infant with jaundice and thrombocytopenia..” The New England Journal of Medicine 353, no. 2 (July 2005): 189–98. https://doi.org/10.1056/nejmcpc059016.
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  - Andrews, Nancy C. “Molecular control of iron metabolism..” Best Practice & Research. Clinical Haematology 18, no. 2 (June 2005): 159–69. https://doi.org/10.1016/j.beha.2004.10.004.
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  - Gunshin, Hiromi, Yuko Fujiwara, Angel O. Custodio, Cristina Direnzo, Sylvie Robine, and Nancy C. Andrews. “Slc11a2 is required for intestinal iron absorption and erythropoiesis but dispensable in placenta and liver..” The Journal of Clinical Investigation 115, no. 5 (May 2005): 1258–66. https://doi.org/10.1172/JCI200524356.
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  - Tolosano, Emanuela, Sharmila Fagoonee, Cinzia Garuti, Linda Valli, Nancy C. Andrews, Fiorella Altruda, and Antonello Pietrangelo. “Haptoglobin modifies the hemochromatosis phenotype in mice..” Blood 105, no. 8 (April 2005): 3353–55. https://doi.org/10.1182/blood-2004-07-2814.
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  - Donovan, Adriana, Christine A. Lima, Jack L. Pinkus, Geraldine S. Pinkus, Leonard I. Zon, Sylvie Robine, and Nancy C. Andrews. “The iron exporter ferroportin/Slc40a1 is essential for iron homeostasis..” Cell Metabolism 1, no. 3 (March 2005): 191–200. https://doi.org/10.1016/j.cmet.2005.01.003.
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  - Roy, Cindy N., and Nancy C. Andrews. “Anemia of inflammation: the hepcidin link..” Current Opinion in Hematology 12, no. 2 (March 2005): 107–11. https://doi.org/10.1097/00062752-200503000-00001.
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  - Andrews, Nancy C. “Probing the iron pool. Focus on "Detection of intracellular iron by its regulatory effect"..” American Journal of Physiology. Cell Physiology 287, no. 6 (December 2004): C1537–38. https://doi.org/10.1152/ajpcell.00435.2004.
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  - Heeney, Matthew M., and Nancy C. Andrews. “Iron homeostasis and inherited iron overload disorders: an overview..” Hematology/Oncology Clinics of North America 18, no. 6 (December 2004): 1379–ix. https://doi.org/10.1016/j.hoc.2004.06.018.
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  - Andrews, Nancy C. “Pathophysiologic mechanisms of anemia of chronic disease..” Postgraduate Medicine 116, no. 5 Suppl Anemia (November 2004): 17–22. https://doi.org/10.3810/pgm.11.2004.suppl36.250.
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  - Huang, Franklin W., Isabel Rubio-Aliaga, James P. Kushner, Nancy C. Andrews, and Mark D. Fleming. “Identification of a novel mutation (C321X) in HJV..” Blood 104, no. 7 (October 2004): 2176–77. https://doi.org/10.1182/blood-2004-01-0400.
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  - Macedo, M Fatima, Maria de Sousa, Renee M. Ned, Claudia Mascarenhas, Nancy C. Andrews, and Margarida Correia-Neves. “Transferrin is required for early T-cell differentiation..” Immunology 112, no. 4 (August 2004): 543–49. https://doi.org/10.1111/j.1365-2567.2004.01915.x.
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  - Andrews, Nancy C. “Anemia of inflammation: the cytokine-hepcidin link..” The Journal of Clinical Investigation 113, no. 9 (May 2004): 1251–53. https://doi.org/10.1172/JCI200421441.
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  - Roy, Cindy N., Angel O. Custodio, Jos de Graaf, Susanne Schneider, Imo Akpan, Lynne K. Montross, Mayka Sanchez, et al. “An Hfe-dependent pathway mediates hyposideremia in response to lipopolysaccharide-induced inflammation in mice..” Nature Genetics 36, no. 5 (May 2004): 481–85. https://doi.org/10.1038/ng1350.
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  - Derjuga, Anna, Tania S. Gourley, Teresa M. Holm, Henry H. Q. Heng, Ramesh A. Shivdasani, Rafi Ahmed, Nancy C. Andrews, and Volker Blank. “Complexity of CNC transcription factors as revealed by gene targeting of the Nrf3 locus..” Molecular and Cellular Biology 24, no. 8 (April 2004): 3286–94. https://doi.org/10.1128/MCB.24.8.3286-3294.2004.
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  - Hentze, Matthias W., Martina U. Muckenthaler, and Nancy C. Andrews. “Balancing acts: molecular control of mammalian iron metabolism..” Cell 117, no. 3 (April 2004): 285–97. https://doi.org/10.1016/s0092-8674(04)00343-5.
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  - Miranda, Carlos J., Hortence Makui, Nancy C. Andrews, and Manuela M. Santos. “Contributions of beta2-microglobulin-dependent molecules and lymphocytes to iron regulation: insights from HfeRag1(-/-) and beta2mRag1(-/-) double knock-out mice..” Blood 103, no. 7 (April 2004): 2847–49. https://doi.org/10.1182/blood-2003-09-3300.
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  - Nicolas, Gaël, Nancy C. Andrews, Axel Kahn, and Sophie Vaulont. “Hepcidin, a candidate modifier of the hemochromatosis phenotype in mice..” Blood 103, no. 7 (April 2004): 2841–43. https://doi.org/10.1182/blood-2003-09-3358.
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  - Xu, Haoxing, Jie Jin, Louis J. DeFelice, Nancy C. Andrews, and David E. Clapham. “A spontaneous, recurrent mutation in divalent metal transporter-1 exposes a calcium entry pathway..” Plos Biology 2, no. 3 (March 16, 2004). https://doi.org/10.1371/journal.pbio.0020050.
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  - Andrews, N. C. “Pathophysiologic mechanisms of anemia of chronic disease..” Postgraduate Medicine 116, no. 5 Suppl Anemia (2004): 17–22. https://doi.org/10.3810/pgm.11.2004.suppl36.250.
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  - Donovan, Adriana, and Nancy Catherine Andrews. “The molecular regulation of iron metabolism..” The Hematology Journal : The Official Journal of the European Haematology Association 5, no. 5 (January 2004): 373–80. https://doi.org/10.1038/sj.thj.6200540.
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  - Ned, Renee M., Wojciech Swat, and Nancy C. Andrews. “Transferrin receptor 1 is differentially required in lymphocyte development..” Blood 102, no. 10 (November 2003): 3711–18. https://doi.org/10.1182/blood-2003-04-1086.
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  - Miranda, Carlos J., Hortence Makui, Ricardo J. Soares, Marc Bilodeau, Jeannie Mui, Hajatollah Vali, Richard Bertrand, Nancy C. Andrews, and Manuela M. Santos. “Hfe deficiency increases susceptibility to cardiotoxicity and exacerbates changes in iron metabolism induced by doxorubicin..” Blood 102, no. 7 (October 2003): 2574–80. https://doi.org/10.1182/blood-2003-03-0869.
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  - Braun, Anne, Songwen Zhang, Helena E. Miettinen, Shamsah Ebrahim, Teresa M. Holm, Eliza Vasile, Mark J. Post, et al. “Probucol prevents early coronary heart disease and death in the high-density lipoprotein receptor SR-BI/apolipoprotein E double knockout mouse..” Proceedings of the National Academy of Sciences of the United States of America 100, no. 12 (June 2003): 7283–88. https://doi.org/10.1073/pnas.1237725100.
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  - Muckenthaler, Martina, Cindy N. Roy, Angel O. Custodio, Belén Miñana, Jos deGraaf, Lynne K. Montross, Nancy C. Andrews, and Matthias W. Hentze. “Regulatory defects in liver and intestine implicate abnormal hepcidin and Cybrd1 expression in mouse hemochromatosis..” Nature Genetics 34, no. 1 (May 2003): 102–7. https://doi.org/10.1038/ng1152.
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  - Nicolas, Gaël, Lydie Viatte, Dan-Qing Lou, Myriam Bennoun, Carole Beaumont, Axel Kahn, Nancy C. Andrews, and Sophie Vaulont. “Constitutive hepcidin expression prevents iron overload in a mouse model of hemochromatosis..” Nature Genetics 34, no. 1 (May 2003): 97–101. https://doi.org/10.1038/ng1150.
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  - Roy, Cindy N., David A. Weinstein, and Nancy C. Andrews. “2002 E. Mead Johnson Award for Research in Pediatrics Lecture: the molecular biology of the anemia of chronic disease: a hypothesis..” Pediatric Research 53, no. 3 (March 2003): 507–12. https://doi.org/10.1203/01.pdr.0000049513.67410.2d.
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  - Santos, Manuela M., Carlos J. Miranda, Joanne E. Levy, Lynne K. Montross, Mireille Cossée, Jorge Sequeiros, Nancy Andrews, Michel Koenig, and Massimo Pandolfo. “Iron metabolism in mice with partial frataxin deficiency..” Cerebellum (London, England) 2, no. 2 (January 2003): 146–53. https://doi.org/10.1080/14734220309408.
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  - Weinstein, David A., Cindy N. Roy, Mark D. Fleming, Massimo F. Loda, Joseph I. Wolfsdorf, and Nancy C. Andrews. “Inappropriate expression of hepcidin is associated with iron refractory anemia: implications for the anemia of chronic disease..” Blood 100, no. 10 (November 2002): 3776–81. https://doi.org/10.1182/blood-2002-04-1260.
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  - Andrews, Nancy C. “A genetic view of iron homeostasis..” Seminars in Hematology 39, no. 4 (October 2002): 227–34. https://doi.org/10.1053/shem.2002.35632.
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  - Ajioka, Richard S., Joanne E. Levy, Nancy C. Andrews, and James P. Kushner. “Regulation of iron absorption in Hfe mutant mice..” Blood 100, no. 4 (August 2002): 1465–69. https://doi.org/10.1182/blood-2001-11-0037.
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  - Andrews, Nancy C. “The other physician-scientist problem: where have all the young girls gone?.” Nature Medicine 8, no. 5 (May 2002): 439–41. https://doi.org/10.1038/nm0502-439.
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  - Andrews, Nancy C. “Metal transporters and disease..” Current Opinion in Chemical Biology 6, no. 2 (April 2002): 181–86. https://doi.org/10.1016/s1367-5931(02)00307-1.
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  - Holm, Teresa M., Anne Braun, Bernardo L. Trigatti, Carlo Brugnara, Masa Sakamoto, Monty Krieger, and Nancy C. Andrews. “Failure of red blood cell maturation in mice with defects in the high-density lipoprotein receptor SR-BI..” Blood 99, no. 5 (March 2002): 1817–24. https://doi.org/10.1182/blood.v99.5.1817.
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  - Andrews, Nancy C. “Animal models of hereditary iron transport disorders..” Advances in Experimental Medicine and Biology 509 (January 2002): 1–17.
  - Gunshin, H., C. R. Allerson, M. Polycarpou-Schwarz, A. Rofts, J. T. Rogers, F. Kishi, M. W. Hentze, T. A. Rouault, N. C. Andrews, and M. A. Hediger. “Iron-dependent regulation of the divalent metal ion transporter..” Febs Letters 509, no. 2 (December 2001): 309–16. https://doi.org/10.1016/s0014-5793(01)03189-1.
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  - Roy, C. N., and N. C. Andrews. “Recent advances in disorders of iron metabolism: mutations, mechanisms and modifiers..” Human Molecular Genetics 10, no. 20 (October 2001): 2181–86. https://doi.org/10.1093/hmg/10.20.2181.
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  - Montosi, G., A. Donovan, A. Totaro, C. Garuti, E. Pignatti, S. Cassanelli, C. C. Trenor, P. Gasparini, N. C. Andrews, and A. Pietrangelo. “Autosomal-dominant hemochromatosis is associated with a mutation in the ferroportin (SLC11A3) gene..” The Journal of Clinical Investigation 108, no. 4 (August 2001): 619–23. https://doi.org/10.1172/jci13468.
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  - Andrews, N. C. “Mining copper transport genes..” Proceedings of the National Academy of Sciences of the United States of America 98, no. 12 (June 2001): 6543–45. https://doi.org/10.1073/pnas.131192498.
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  - Knutson, M. D., J. E. Levy, N. C. Andrews, and M. Wessling-Resnick. “Expression of stimulator of Fe transport is not enhanced in Hfe knockout mice..” The Journal of Nutrition 131, no. 5 (May 2001): 1459–64. https://doi.org/10.1093/jn/131.5.1459.
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  - Fleming, M. D., D. R. Campagna, J. N. Haslett, C. C. Trenor, and N. C. Andrews. “A mutation in a mitochondrial transmembrane protein is responsible for the pleiotropic hematological and skeletal phenotype of flexed-tail (f/f) mice..” Genes & Development 15, no. 6 (March 2001): 652–57. https://doi.org/10.1101/gad.873001.
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  - Canonne-Hergaux, F., J. E. Levy, M. D. Fleming, L. K. Montross, N. C. Andrews, and P. Gros. “Expression of the DMT1 (NRAMP2/DCT1) iron transporter in mice with genetic iron overload disorders..” Blood 97, no. 4 (February 2001): 1138–40. https://doi.org/10.1182/blood.v97.4.1138.
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  - Sinclair, P. R., N. Gorman, H. S. Walton, W. J. Bement, J. F. Sinclair, G. S. Gerhard, J. G. Szakacs, N. C. Andrews, and J. E. Levy. “Uroporphyria in Hfe mutant mice given 5-aminolevulinate: a new model of Fe-mediated porphyria cutanea tarda..” Hepatology (Baltimore, Md.) 33, no. 2 (February 2001): 406–12. https://doi.org/10.1053/jhep.2001.21409.
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  - Phillips, J. D., L. K. Jackson, M. Bunting, M. R. Franklin, K. R. Thomas, J. E. Levy, N. C. Andrews, and J. P. Kushner. “A mouse model of familial porphyria cutanea tarda..” Proceedings of the National Academy of Sciences of the United States of America 98, no. 1 (January 2001): 259–64. https://doi.org/10.1073/pnas.011481398.
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  - Andrews, N. C. “Inherited iron overload disorders..” Current Opinion in Pediatrics 12, no. 6 (December 2000): 596–602. https://doi.org/10.1097/00008480-200012000-00015.
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  - Andrews, N. C. “Iron metabolism and absorption.” Reviews in Clinical and Experimental Hematology 4, no. 4 (December 1, 2000): 283–301. https://doi.org/10.1046/j.1468-0734.2000.00021.x.
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  - Andrews, N. C. “Iron homeostasis: insights from genetics and animal models..” Nature Reviews. Genetics 1, no. 3 (December 2000): 208–17. https://doi.org/10.1038/35042073.
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  - Canonne-Hergaux, F., M. D. Fleming, J. E. Levy, S. Gauthier, T. Ralph, V. Picard, N. C. Andrews, and P. Gros. “The Nramp2/DMT1 iron transporter is induced in the duodenum of microcytic anemia mk mice but is not properly targeted to the intestinal brush border..” Blood 96, no. 12 (December 2000): 3964–70.
  - West, A. P., M. J. Bennett, V. M. Sellers, N. C. Andrews, C. A. Enns, and P. J. Bjorkman. “Comparison of the interactions of transferrin receptor and transferrin receptor 2 with transferrin and the hereditary hemochromatosis protein HFE..” The Journal of Biological Chemistry 275, no. 49 (December 2000): 38135–38. https://doi.org/10.1074/jbc.c000664200.
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  - Sayer, M. S., P. A. Tilbrook, A. Spadaccini, E. Ingley, M. K. Sarna, J. H. Williams, N. C. Andrews, and S. P. Klinken. “Ectopic expression of transcription factor NF-E2 alters the phenotype of erythroid and monoblastoid cells..” The Journal of Biological Chemistry 275, no. 33 (August 2000): 25292–98. https://doi.org/10.1074/jbc.m908695199.
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  - Trenor, C. C., D. R. Campagna, V. M. Sellers, N. C. Andrews, and M. D. Fleming. “The molecular defect in hypotransferrinemic mice..” Blood 96, no. 3 (August 2000): 1113–18.
  - Levy, J. E., L. K. Montross, and N. C. Andrews. “Genes that modify the hemochromatosis phenotype in mice..” The Journal of Clinical Investigation 105, no. 9 (May 2000): 1209–16. https://doi.org/10.1172/jci9635.
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  - Conrad, M. E., and J. N. Umbreit. “Disorders of iron metabolism..” The New England Journal of Medicine 342, no. 17 (April 2000): 1293–94. https://doi.org/10.1056/nejm200004273421716.
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  - Donovan, A., A. Brownlie, Y. Zhou, J. Shepard, S. J. Pratt, J. Moynihan, B. H. Paw, et al. “Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter..” Nature 403, no. 6771 (February 2000): 776–81. https://doi.org/10.1038/35001596.
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  - Andrews, N. C. “Iron metabolism: iron deficiency and iron overload..” Annual Review of Genomics and Human Genetics 1 (January 2000): 75–98. https://doi.org/10.1146/annurev.genom.1.1.75.
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  - Andrews, N. C. “Iron metabolism: Iron deficiency and iron overload.” Annual Review of Genomics and Human Genetics 1, no. 2000 (2000): 75–98.
  - Andrews, N. C. “Intestinal iron absorption: current concepts circa 2000..” Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 32, no. 1 (January 2000): 56–61. https://doi.org/10.1016/s1590-8658(00)80045-6.
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  - Andrews, N. C. “Disorders of iron metabolism..” The New England Journal of Medicine 341, no. 26 (December 1999): 1986–95. https://doi.org/10.1056/nejm199912233412607.
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  - Andrews, N. C. “The iron transporter DMT1..” The International Journal of Biochemistry & Cell Biology 31, no. 10 (October 1999): 991–94. https://doi.org/10.1016/s1357-2725(99)00065-5.
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  - Andrews, N. C., and M. D. Fleming. “Commentary on: ferrokinetics in the syndrome of familial hypoferremic microcytic anemia with iron malabsorption..” Journal of Pediatric Hematology/Oncology 21, no. 5 (September 1999): 353–55. https://doi.org/10.1097/00043426-199909000-00004.
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  - Levy, J. E., L. K. Montross, D. E. Cohen, M. D. Fleming, and N. C. Andrews. “The C282Y mutation causing hereditary hemochromatosis does not produce a null allele..” Blood 94, no. 1 (July 1999): 9–11.
  - Andrews, N. C., M. D. Fleming, and H. Gunshin. “Iron transport across biologic membranes..” Nutrition Reviews 57, no. 4 (April 1999): 114–23. https://doi.org/10.1111/j.1753-4887.1999.tb06934.x.
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  - Levy, J. E., O. Jin, Y. Fujiwara, F. Kuo, and N. C. Andrews. “Transferrin receptor is necessary for development of erythrocytes and the nervous system..” Nature Genetics 21, no. 4 (April 1999): 396–99. https://doi.org/10.1038/7727.
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  - Andrews, N. C., M. D. Fleming, and J. E. Levy. “Molecular insights into mechanisms of iron transport..” Current Opinion in Hematology 6, no. 2 (March 1999): 61–64. https://doi.org/10.1097/00062752-199903000-00001.
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  - Fleming, M. D., and N. C. Andrews. “Mammalian iron transport: an unexpected link between metal homeostasis and host defense..” The Journal of Laboratory and Clinical Medicine 132, no. 6 (December 1998): 464–68. https://doi.org/10.1016/s0022-2143(98)90123-8.
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  - Andrews, N. C., and J. E. Levy. “Iron is hot: an update on the pathophysiology of hemochromatosis..” Blood 92, no. 6 (September 1998): 1845–51.
  - Su, M. A., C. C. Trenor, J. C. Fleming, M. D. Fleming, and N. C. Andrews. “The G185R mutation disrupts function of the iron transporter Nramp2..” Blood 92, no. 6 (September 1998): 2157–63.
  - Yang, A., M. Kaghad, Y. Wang, E. Gillett, M. D. Fleming, V. Dötsch, N. C. Andrews, D. Caput, and F. McKeon. “p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities..” Molecular Cell 2, no. 3 (September 1998): 305–16. https://doi.org/10.1016/s1097-2765(00)80275-0.
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  - Versaw, W. K., V. Blank, N. M. Andrews, and E. H. Bresnick. “Mitogen-activated protein kinases enhance long-range activation by the beta-globin locus control region..” Proceedings of the National Academy of Sciences of the United States of America 95, no. 15 (July 1998): 8756–60. https://doi.org/10.1073/pnas.95.15.8756.
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  - Andrews, N. C. “The NF-E2 transcription factor..” The International Journal of Biochemistry & Cell Biology 30, no. 4 (April 1998): 429–32. https://doi.org/10.1016/s1357-2725(97)00135-0.
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  - Fleming, M. D., M. A. Romano, M. A. Su, L. M. Garrick, M. D. Garrick, and N. C. Andrews. “Nramp2 is mutated in the anemic Belgrade (b) rat: evidence of a role for Nramp2 in endosomal iron transport..” Proceedings of the National Academy of Sciences of the United States of America 95, no. 3 (February 1998): 1148–53. https://doi.org/10.1073/pnas.95.3.1148.
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  - Blank, V., and N. C. Andrews. “The Maf transcription factors: regulators of differentiation..” Trends in Biochemical Sciences 22, no. 11 (November 1997): 437–41. https://doi.org/10.1016/s0968-0004(97)01105-5.
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  - Deveaux, S., S. Cohen-Kaminsky, R. A. Shivdasani, N. C. Andrews, A. Filipe, I. Kuzniak, S. H. Orkin, P. H. Roméo, and V. Mignotte. “p45 NF-E2 regulates expression of thromboxane synthase in megakaryocytes..” The Embo Journal 16, no. 18 (September 1997): 5654–61. https://doi.org/10.1093/emboj/16.18.5654.
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  - Blank, V., J. H. Knoll, and N. C. Andrews. “Molecular characterization and localization of the human MAFG gene..” Genomics 44, no. 1 (August 1997): 147–49. https://doi.org/10.1006/geno.1997.4847.
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  - Fleming, M. D., C. C. Trenor, M. A. Su, D. Foernzler, D. R. Beier, W. F. Dietrich, and N. C. Andrews. “Microcytic anaemia mice have a mutation in Nramp2, a candidate iron transporter gene..” Nature Genetics 16, no. 4 (August 1997): 383–86. https://doi.org/10.1038/ng0897-383.
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  - Blank, V., M. J. Kim, and N. C. Andrews. “Human MafG is a functional partner for p45 NF-E2 in activating globin gene expression..” Blood 89, no. 11 (June 1997): 3925–35.
  - Andrews, N. C. “Iron deficiency: lessons from anemic mice..” The Yale Journal of Biology and Medicine 70, no. 3 (May 1997): 219–26.
  - Cheng, X., M. J. Reginato, N. C. Andrews, and M. A. Lazar. “The transcriptional integrator CREB-binding protein mediates positive cross talk between nuclear hormone receptors and the hematopoietic bZip protein p45/NF-E2..” Molecular and Cellular Biology 17, no. 3 (March 1997): 1407–16. https://doi.org/10.1128/mcb.17.3.1407.
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  - Andrews, N. C., and C. M. Bennett. “Disorders of red cell iron during infancy and childhood.” International Journal of Pediatric Hematology/Oncology 4, no. 2 (January 1, 1997): 171–80.
  - Walters, M., N. C. Andrews, W. Magis, and D. I. Martin. “Erythroid AP-1/NF-E2 elements vary in their response to NF-E2..” Experimental Hematology 24, no. 3 (February 1996): 445–52.
  - Parsons, S. K., M. D. Fleming, D. Phil, D. G. Nathan, and N. C. Andrews. “Iron deficiency anemia associated with an error of iron metabolism in two siblings: A thirty year follow up.” Hematology 1, no. 1 (January 1, 1996): 65–73. https://doi.org/10.1080/10245332.1996.11746287.
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  - Engeland, K., N. C. Andrews, and B. Mathey-Prevot. “Multiple proteins interact with the nuclear inhibitory protein repressor element in the human interleukin-3 promoter..” J Biol Chem 270, no. 41 (October 13, 1995): 24572–79. https://doi.org/10.1074/jbc.270.41.24572.
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  - Ney, P. A., S. F. Farina, D. M. Bodine, N. C. Andrews, S. H. Orkin, and A. W. Neinhuis. “Microcytic anemia in mk/mk mice is not corrected by retroviral-mediated gene transfer of wild-type p45 NF-E2..” Experimental Hematology 23, no. 1 (January 1995): 74–80.
  - Trenor, C., W. Lin, and N. C. Andrews. “Novel bacterial P-type ATPases with histidine-rich heavy-metal-associated sequences..” Biochemical and Biophysical Research Communications 205, no. 3 (December 1994): 1644–50. https://doi.org/10.1006/bbrc.1994.2856.
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  - Andrews, N. C. “Erythroid transcription factor NF-E2 coordinates hemoglobin synthesis..” Pediatric Research 36, no. 4 (October 1994): 419–23. https://doi.org/10.1203/00006450-199410000-00001.
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  - Lim, K. C., H. Ishihara, R. D. Riddle, Z. Yang, N. Andrews, M. Yamamoto, and J. D. Engel. “Structure and regulation of the chicken erythroid delta-aminolevulinate synthase gene..” Nucleic Acids Research 22, no. 7 (April 1994): 1226–33. https://doi.org/10.1093/nar/22.7.1226.
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  - Andrews, N. C., and S. H. Orkin. “Transcriptional control of erythropoiesis..” Current Opinion in Hematology 1, no. 2 (March 1994): 119–24.
  - Peters, L. L., N. C. Andrews, E. M. Eicher, M. B. Davidson, S. H. Orkin, and S. E. Lux. “Mouse microcytic anaemia caused by a defect in the gene encoding the globin enhancer-binding protein NF-E2 [8].” Nature 371, no. 6495 (January 1, 1994). https://doi.org/10.1038/371358b0.
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  - Peters, L. L., N. C. Andrews, E. M. Eicher, M. B. Davidson, S. H. Orkin, and S. E. Lux. “Erratum: Mouse microcytic anaemia caused by a defect in the gene encoding the globin enhancer-binding protein NF-E2 (Nature 362, 768-770 (1992)).” Nature 371, no. 6495 (1994).
  - Andrews, N. C., K. J. Kotkow, P. A. Ney, H. Erdjument-Bromage, P. Tempst, and S. H. Orkin. “The ubiquitous subunit of erythroid transcription factor NF-E2 is a small basic-leucine zipper protein related to the v-maf oncogene..” Proceedings of the National Academy of Sciences of the United States of America 90, no. 24 (December 1993): 11488–92. https://doi.org/10.1073/pnas.90.24.11488.
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  - Ney, P. A., N. C. Andrews, S. M. Jane, B. Safer, M. E. Purucker, S. Weremowicz, C. C. Morton, S. C. Goff, S. H. Orkin, and A. W. Nienhuis. “Purification of the human NF-E2 complex: cDNA cloning of the hematopoietic cell-specific subunit and evidence for an associated partner..” Molecular and Cellular Biology 13, no. 9 (September 1993): 5604–12. https://doi.org/10.1128/mcb.13.9.5604.
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  - Andrews, N. C., H. Erdjument-Bromage, M. B. Davidson, P. Tempst, and S. H. Orkin. “Erythroid transcription factor NF-E2 is a haematopoietic-specific basic-leucine zipper protein..” Nature 362, no. 6422 (April 1993): 722–28. https://doi.org/10.1038/362722a0.
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  - Peters, L. L., N. C. Andrews, E. M. Eicher, M. B. Davidson, S. H. Orkin, and S. E. Lux. “Mouse microcytic anaemia caused by a defect in the gene encoding the globin enhancer-binding protein NF-E2..” Nature 362, no. 6422 (April 1993): 768–70. https://doi.org/10.1038/362768a0.
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  - Liboi, E., P. Jubinsky, N. C. Andrews, D. G. Nathan, and B. Mathey-Prevot. “Enhanced expression of interleukin-3 and granulocyte-macrophage colony-stimulating factor receptor subunits in murine hematopoietic cells stimulated with hematopoietic growth factors..” Blood 80, no. 5 (September 1992): 1183–89.
  - Strauss, E. C., N. C. Andrews, D. R. Higgs, and S. H. Orkin. “In vivo footprinting of the human alpha-globin locus upstream regulatory element by guanine and adenine ligation-mediated polymerase chain reaction..” Molecular and Cellular Biology 12, no. 5 (May 1992): 2135–42. https://doi.org/10.1128/mcb.12.5.2135.
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  - Andrews, N. C., and D. V. Faller. “A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells..” Nucleic Acids Research 19, no. 9 (May 1991). https://doi.org/10.1093/nar/19.9.2499.
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  - Mathey-Prevot, B., N. C. Andrews, H. S. Murphy, S. G. Kreissman, and D. G. Nathan. “Positive and negative elements regulate human interleukin 3 expression..” Proceedings of the National Academy of Sciences of the United States of America 87, no. 13 (July 1990): 5046–50. https://doi.org/10.1073/pnas.87.13.5046.
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  - ANDREWS, N. C., B. MATHEYPREVOT, S. G. KREISSMAN, and D. G. NATHAN. “NUCLEAR FACTOR BINDING-SITES IN THE INTERLEUKIN (IL-3) PROMOTER.” Pediatric Research 27, no. 4 (April 1, 1990): A138–A138.
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  - Andrews, N. C., B. Mathey-Prevot, H. Murphy, and D. G. Nathan. “Regulation of the human interleukin-3 gene..” Transactions of the Association of American Physicians 102 (January 1989): 240–51.
  - Andrews, N. C., and D. Baltimore. “Lack of evidence for VPg priming of poliovirus RNA synthesis in the host factor-dependent in vitro replicase reaction..” Journal of Virology 58, no. 1 (April 1986): 212–15.
  - Andrews, N. C., and D. Baltimore. “Purification of a terminal uridylyltransferase that acts as host factor in the in vitro poliovirus replicase reaction..” Proceedings of the National Academy of Sciences of the United States of America 83, no. 2 (January 1986): 221–25. https://doi.org/10.1073/pnas.83.2.221.
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  - Andrews, N. C., D. Levin, and D. Baltimore. “Poliovirus replicase stimulation by terminal uridylyl transferase..” The Journal of Biological Chemistry 260, no. 12 (June 1985): 7628–35.
  - Rosa, M. D., and N. C. Andrews. “Phage T3 DNA contains an exact copy of the 23 base-pair phage T7 RNA polymerase promoter sequence..” Journal of Molecular Biology 147, no. 1 (March 1981): 41–53. https://doi.org/10.1016/0022-2836(81)90078-4.
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  - Lerner, M. R., N. C. Andrews, G. Miller, and J. A. Steitz. “Two small RNAs encoded by Epstein-Barr virus and complexed with protein are precipitated by antibodies from patients with systemic lupus erythematosus..” Proceedings of the National Academy of Sciences of the United States of America 78, no. 2 (February 1981): 805–9. https://doi.org/10.1073/pnas.78.2.805.
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  - Garingo, A. D., M. Suhasini, N. C. Andrews, and R. B. Pilz. “cAMP-dependent protein kinase is necessary for increased NF-E2.DNA complex formation during erythroleukemia cell differentiation..” J Biol Chem 270, no. 16 (April 21, 1995): 9169–77. https://doi.org/10.1074/jbc.270.16.9169.
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- Conference Papers
  - Stagg, David B., Sara Gardenghi, Stefano Rivella, Nancy C. Andrews, and Karin E. Finberg. “Genetic Loss of Tmprss6 Increases Effective Erythropoiesis in a Mouse Model of beta-Thalassemia.” In Blood, Vol. 120. AMER SOC HEMATOLOGY, 2012.
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  - Stagg, David B., Sara Gardenghi, Stefano Rivella, Nancy C. Andrews, and Karin E. Finberg. “Genetic Loss of Tmprss6 Increases Effective Erythropoiesis in a Mouse Model of beta-Thalassemia.” In Blood, Vol. 120. AMER SOC HEMATOLOGY, 2012.
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  - Finberg, Karin E., Rebecca L. Whittlesey, Stefano Rivella, and Nancy C. Andrews. “Tmprss6, An Inhibitor of Hepatic Bmp/Smad Signaling, Is Required for Hepcidin Suppression and Iron Loading In a Mouse Model of beta-Thalassemia.” In Blood, 116:75–75. AMER SOC HEMATOLOGY, 2010.
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  - Gardenghi, Sara, Pedro Ramos, Cindy N. Roy, Nancy C. Andrews, Elizabeta Nemeth, Xiuhi An, Mohandas Narla, et al. “Hepcidin as a Therapeutic Tool to Limit Iron Overload and Improve Anemia In beta-Thalassemia.” In Blood, 116:443–44. AMER SOC HEMATOLOGY, 2010.
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  - Wehbe, Ramsey M., Rebecca L. Whittlesey, Nancy C. Andrews, and Karin E. Finberg. “The Serine Protease Tmprss6 Regulates Hepcidin Expression, but Its Loss Does Not Cause Systemic Iron Deficiency In the Fetal and Neonatal Periods.” In Blood, 116:1728–1728. AMER SOC HEMATOLOGY, 2010.
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  - Finberg, Karin E., Rebecca Whittlesey, Mark D. Fleming, and Nancy C. Andrews. “Tmprss6 Is a Genetic Modifier of the Hfe-Hemochromatosis Phenotype in Mice.” In Blood, 114:259–259. AMER SOC HEMATOLOGY, 2009.
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Teaching & Mentoring
Recent Courses
- PHARM 394: Research Independent Study 2017

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