Scholars@Duke
Nazema Y. Siddiqui

Nazema Y. Siddiqui

Associate Professor of Obstetrics and Gynecology
Obstetrics and Gynecology, Urogynecology
nazema.siddiqui@duke.edu
Duke University Medical Center, Durham, NC 27617
5324 McFarland Drive Suite 310, Box 3912, Durham, NC 27617
Office hours 8:00AM - 4:30PM Mon-Fri  

Scholarly Works - Journal articles

Sacral Neuromodulation for Refractory Overactive Bladder: Closing the Gaps in Anatomy, Mechanisms, and Parameter Selection.

Journal article Adv Ther · June 30, 2026 Sacral neuromodulation is an effective therapy to control overactive bladder symptoms, yet the underlying mechanisms and optimal stimulation parameters remain unclear. Analysis of 45 clinical studies from 1994 to 2023 demonstrated no significant change in ... Full text Link to item Cite

Goal Achievement in Women With Urinary Incontinence After Midurethral Sling.

Journal article Urogynecology (Phila) · June 18, 2026 IMPORTANCE: Treatment goals are understudied among women undergoing midurethral sling (MUS) surgery for mixed urinary incontinence (MUI). OBJECTIVES: The objectives of this study were to describe treatment goals in participants with MUI undergoing MUS with ... Full text Link to item Cite

Stool Microbiota, Metabolites, and Fecal Incontinence in Women.

Journal article Urogynecology (Phila) · June 1, 2026 IMPORTANCE: Stool metabolites influencing gut motility and sensation may contribute to fecal incontinence (FI). OBJECTIVE: The objective of this study was to test whether FI is associated with higher levels of butyrate and Clostridiales taxa in stool. STUD ... Full text Link to item Cite

MRI 2-D Parameters Associated with Native Tissue or Transvaginal Mesh Surgical Apical Prolapse Repair Failure.

Journal article Int Urogynecol J · May 30, 2026 INTRODUCTION AND HYPOTHESIS: Magnetic resonance imaging (MRI) can evaluate individual components of postsurgical recurrent prolapse that may not be visible on physical examination and provide insights into mechanisms of prolapse recurrence. METHODS: This p ... Full text Link to item Cite

Symptoms and subtypes of patients with lower urinary tract dysfunction - insights from the Symptoms of Lower Urinary Tract Dysfunction Research Network.

Journal article Nat Rev Urol · May 27, 2026 Lower urinary tract dysfunction presents with a wide range of bothersome urinary symptoms, which are common in both men and women, with incidence and prevalence increasing with age. Individuals with lower urinary tract symptoms (LUTS) suffer from the chron ... Full text Link to item Cite

The LURN Study-What Have We "LURN"ed So Far?

Journal article Neurourol Urodyn · April 2026 LURN was established by the NIDDK to study LUTS with a holistic approach, focusing on urinary urgency. LURN has developed patient-reported outcome instruments to better measure LUTS in men and women. LURN SI-29 can be used for clinical research. LURN SI-10 ... Full text Link to item Cite

Content Validity of a Patient-Reported Measure of Postoperative Recovery.

Journal article Urogynecology (Phila) · February 12, 2026 IMPORTANCE: Despite increasing focus on the benefits of expedited recovery after minimally invasive surgery (MIS), urogynecology lacks a validated, simple question to assess recovery. OBJECTIVES: The objectives of this study were to explore how patients ev ... Full text Link to item Cite

A negative binomial latent factor model for paired microbiome sequencing data.

Journal article BMC Bioinformatics · January 22, 2026 BACKGROUND: Microbiome sequencing data are often collected from several body sites and exhibit dependencies. Our objective is to develop a model that enables joint analysis of data from different sites by capturing the underlying cross-site dependencies. T ... Full text Link to item Cite

Can Pharmacogenetics Be Used to Predict the Response to Fesoterodine Fumarate?

Journal article Urogynecology (Phila) · January 1, 2026 IMPORTANCE: Pharmacogenetics could address the challenge of predicting an individual's response to anticholinergic medications for urgency urinary incontinence (UUI). OBJECTIVES: Our objectives were to evaluate whether the metabolizer status of cytochrome ... Full text Link to item Cite

Management of Asymptomatic Bacteriuria in Adult Female Populations.

Journal article Obstet Gynecol Surv · December 1, 2025 (Abstracted from Urogynecology 2025;31(9):827-845) Studies have shown that antimicrobial treatment for asymptomatic bacteriuria (ASB) is not beneficial and is associated with more antibiotic resistance, infection, and longer hospital stays. As a result of ... Full text Link to item Cite

Updates in Clinical Management of Recurrent Urinary Tract Infections.

Journal article Obstet Gynecol · November 1, 2025 Urinary tract infections (UTIs) are common and burdensome in women. Here, we discuss challenges with our current models of care and how evolving insights into the female urogenital microbiome have advanced the understanding of how we diagnose, treat, and p ... Full text Link to item Cite

Initial Validation of AUGS-PERFORM: Construct Validity and Test-Retest Reliability.

Journal article Urogynecology (Phila) · October 1, 2025 IMPORTANCE: The A merican U ro g ynecologic S ociety's P rolapse p ERFOR mance M easure (AUGS- PERFORM ) patient-reported outcome measure contains 11 items designed to assess symptoms relevant for assessing the quality of treatment for pelvic organ prolaps ... Full text Link to item Cite

Management of Asymptomatic Bacteriuria in Adult Female Populations.

Journal article Urogynecology (Phila) · September 1, 2025 This Clinical Consensus Statement on the management of asymptomatic bacteriuria (ASB) in adult females reflects statements drafted by content experts within the American Urogynecologic Society Bacteriuria Writing Group. The writing group created 32 clinica ... Full text Link to item Cite

Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN II) Urinary Urgency Phenotyping Study: Methods and Baseline Urinary Symptoms by Age and Sex.

Journal article Neurourol Urodyn · June 2025 AIMS: To present the methods and baseline findings from a prospective, longitudinal cohort study of treatment seeking adults with urinary urgency (URG) with or without urgency urinary incontinence (UUI). METHODS: Adults seeking treatment for URG and/or UUI ... Full text Link to item Cite

Expanded Physiological Testing of the Lower Urinary Tract in Asymptomatic Women and Those With Urgency Urinary Incontinence: Findings From the LURN-Organ Study.

Journal article Neurourol Urodyn · June 2025 PURPOSE: To investigate sensory and motor function of the bladder and urethra in women with and without urgency urinary incontinence (UUI). MATERIALS AND METHODS: Treatment-seeking women with UUI and healthy, asymptomatic, nontreatment seeking controls enr ... Full text Link to item Cite

Commensal bacteria inhibit viral infections via a tryptophan metabolite.

Journal article bioRxiv · May 12, 2025 Clinical outcomes following viral exposures exhibit substantial interindividual variability. Although developing evidence suggests commensal bacteria modulate viral infections, the specific bacteria and mechanisms remain underexplored. Here we define a pat ... Full text Link to item Cite

Draft genomes of Klebsiella pneumoniae and Streptococcus anginosus strains found in the urine of the same female patient.

Journal article Microbiol Resour Announc · April 10, 2025 Here, we report the draft genomes of Klebsiella pneumoniae 5008-1 and Streptococcus anginosus 5008-2 strains isolated from a catheterized urine sample obtained from an asymptomatic postmenopausal woman diagnosed with recurrent urinary tract infection and r ... Full text Link to item Cite

Extended Treatment-dose Antibiotic Therapy vs Low-dose Prophylaxis for the Management of Recurrent Uncomplicated Urinary Tract Infections in Peri- and Post-menopausal Women.

Journal article Urology · April 2025 OBJECTIVE: To assess treatment efficacy over 1year in women with recurrent urinary tract infection (UTI) receiving extended treatment-strength antibiotics compared to standard low-dose prophylactic antibiotic regimens. METHODS: A retrospective cohort study ... Full text Link to item Cite

Postoperative Sexual Function After Vaginal Surgery and Clitoral Size, Position, and Shape.

Journal article JAMA Surg · April 1, 2025 IMPORTANCE: Transvaginal surgery is commonly performed to treat pelvic organ prolapse. Little research focuses on how sexual function relates to clitoral anatomy after vaginal surgery despite the clitoris' role in the sexual response. OBJECTIVE: To determi ... Full text Link to item Cite

State-of-the-Art Review: Recurrent Uncomplicated Urinary Tract Infections in Women.

Journal article Clin Infect Dis · March 17, 2025 Over 50% of adult women experience at least 1 urinary tract infection (UTI) in their lifetime, and almost one-quarter of them will experience a recurrent UTI (rUTI). Recurrent UTI is defined as ≥2 UTIs in a 6-month period or ≥3 UTIs in 12 months (at least ... Full text Open Access Link to item Cite

The Role of Sleep Apnea in Postoperative Neurocognitive Disorders Among Older Noncardiac Surgery Patients: A Prospective Cohort Study.

Journal article Anesth Analg · January 1, 2025 BACKGROUND: Obstructive sleep apnea is associated with increased dementia risk, yet its role in postoperative neurocognitive disorders is unclear. Here, we studied whether the severity of untreated obstructive sleep apnea is associated with the severity of ... Full text Open Access Link to item Cite

Lack of group-to-individual generalizability in people with lower urinary tract symptoms emphasizes the need for deep phenotyping and personalized treatments.

Journal article J Clin Transl Sci · 2025 INTRODUCTION: Understanding how different symptoms co-occur and are correlated may provide insights into the pathophysiology of disease. The lack of group-to-individual generalizability of co-occurrence of symptoms was recently demonstrated by comparing in ... Full text Link to item Cite

What Should I Know About Recurrent UTIs in Older Women?

Journal article JAMA Intern Med · August 1, 2024 Full text Link to item Cite

Structural Changes in Brain White Matter Tracts Associated With Overactive Bladder Revealed by Diffusion Tensor Magnetic Resonance Imaging: Findings From a Symptoms of Lower Urinary Tract Dysfunction Research Network Cross-Sectional Case-Control Study.

Journal article J Urol · August 2024 PURPOSE: Our objective was to investigate structural changes in brain white matter tracts using diffusion tensor imaging (DTI) in patients with overactive bladder (OAB). MATERIALS AND METHODS: Treatment-seeking OAB patients and matched controls enrolled in ... Full text Link to item Cite

Proposing the "Continuum of UTI" for a Nuanced Approach to Diagnosis and Management of Urinary Tract Infections.

Journal article J Urol · May 2024 PURPOSE: Patients with suspected UTIs are categorized into 3 clinical phenotypes based on current guidelines: no UTI, asymptomatic bacteriuria (ASB), or UTI. However, all patients may not fit neatly into these groups. Our objective was to characterize clin ... Full text Link to item Cite

Urinary microbiome community types associated with urinary incontinence severity in women.

Journal article Am J Obstet Gynecol · March 2024 BACKGROUND: Urinary microbiome (urobiome) studies have previously reported on specific taxa and community differences in women with mixed urinary incontinence compared with controls. Therefore, a hypothesis was made that higher urinary and vaginal microbio ... Full text Link to item Cite

Vaginal morphology and position associated with prolapse recurrence after vaginal surgery: A secondary analysis of the DEMAND study.

Journal article BJOG · February 2024 OBJECTIVE: To identify vaginal morphology and position factors associated with prolapse recurrence following vaginal surgery. DESIGN: Secondary analysis of magnetic resonance images (MRI) of the Defining Mechanisms of Anterior Vaginal Wall Descent cross-se ... Full text Link to item Cite

Draft genomes of Lactobacillus delbrueckii and Klebsiella pneumoniae coexisting within a female urinary bladder.

Journal article Microbiol Resour Announc · October 19, 2023 Here, we present the draft genome sequences of Lactobacillus delbrueckii and Klebsiella pneumoniae, both isolated from the urinary bladder of an asymptomatic post-menopausal female patient with a diagnosis of recurrent urinary tract infections. These genom ... Full text Link to item Cite

Adherence to Perioperative Behavioral Therapy With Pelvic Floor Muscle Training in Women Receiving Vaginal Reconstructive Surgery for Pelvic Organ Prolapse.

Journal article Phys Ther · September 1, 2023 OBJECTIVE: The objective of this study was to describe adherence to behavioral and pelvic floor muscle training in women undergoing vaginal reconstructive surgery for organ prolapse and to examine whether adherence was associated with 24-month outcomes. ME ... Full text Link to item Cite

Standard Restrictions vs Expedited Activity After Pelvic Organ Prolapse Surgery: A Randomized Clinical Trial.

Journal article JAMA Surg · August 1, 2023 IMPORTANCE: Restrictions on postoperative activity following pelvic organ prolapse (POP) surgery are not evidence based. Nonetheless, many pelvic surgeons place lifting and activity restrictions on patients following surgery. OBJECTIVE: To evaluate whether ... Full text Link to item Cite

Robot-assisted laparoscopic anterior urethral diverticulectomy.

Journal article Int Urogynecol J · February 2023 INTRODUCTION AND HYPOTHESIS: A 31-year-old patient with a history of fetal sacrococcygeal teratoma requiring tumor resection and pelvic reconstruction in infancy presented with a 3-year history of recurrent vulvar abscesses and voiding dysfunction. Magneti ... Full text Link to item Cite

Natural history of lower urinary tract symptoms in treatment-seeking women with pelvic organ prolapse; the Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN).

Journal article Am J Obstet Gynecol · December 2022 BACKGROUND: The association of pelvic organ prolapse with overactive bladder and other lower urinary tract symptoms, and the natural history of those symptoms are not well characterized. Previous cross-sectional studies demonstrated conflicting relationshi ... Full text Open Access Link to item Cite

Risk of obstetric anal sphincter injuries at the time of admission for delivery: A clinical prediction model.

Journal article BJOG · November 2022 OBJECTIVE: To develop and validate a model to predict obstetric anal sphincter injuries (OASIS) using only information available at the time of admission for labour. DESIGN: A clinical predictive model using a retrospective cohort. SETTING: A US health sys ... Full text Open Access Link to item Cite

Quantifying the Added Value of 2 Common Frailty Measures for Predicting Adverse Outcomes After Elective Hysterectomy.

Journal article Urogynecology (Phila) · August 1, 2022 IMPORTANCE: Although frailty is predictive of adverse outcomes in predominantly male general and orthopedic surgical populations, the utility of American College of Surgeons National Surgical Quality Improvement Program-based frailty measurement for hyster ... Full text Link to item Cite

AUGS-PERFORM: A New Patient-Reported Outcome Measure to Assess Quality of Prolapse Care.

Journal article Female Pelvic Med Reconstr Surg · August 2022 UNLABELLED: Patient-reported outcomes (PRO) are important for measuring quality of care, particularly for interventions aimed at improving symptom bother such as procedures for pelvic organ prolapse. We aimed to create a concise yet comprehensive PRO measu ... Full text Link to item Cite

Draft Genome Sequence of a Lactobacillus gasseri Strain Isolated from the Catheterized Urine of a Healthy Postmenopausal Woman.

Journal article Microbiol Resour Announc · June 16, 2022 Urinary microbiome composition has been found to associate with health status and to change with age. Lactobacillus gasseri is one of the most frequently found lactic acid bacteria in the vaginal and urinary tracts of women. Here, we report a draft genome ... Full text Link to item Cite

Cost-effectiveness of bacteriuria screening before urogynecologic surgery.

Journal article Am J Obstet Gynecol · June 2022 BACKGROUND: Currently, there is controversy over who requires preoperative screening for bacteriuria in the urogynecologic population and whether treating asymptomatic bacteriuria reduces postoperative urinary tract infection rates. OBJECTIVE: To evaluate ... Full text Link to item Cite

Urinary basement membrane graft-augmented sacrospinous ligament suspension: a description of technique and short-term outcomes.

Journal article Int Urogynecol J · May 2022 INTRODUCTION AND HYPOTHESIS: Since the discontinuation of manufacture and distribution of surgical mesh for transvaginal prolapse repair, the use of biologic grafts for transvaginal apical suspension has gained renewed attention. However, there is no FDA-a ... Full text Link to item Cite

Association between the urogenital microbiome and surgical treatment response in women undergoing midurethral sling operation for mixed urinary incontinence.

Journal article Am J Obstet Gynecol · January 2022 BACKGROUND: The urogenital microbiome is associated with urgency and mixed urinary incontinence symptoms and differential treatment responses to pharmacotherapy for urgency urinary incontinence. OBJECTIVE: This study aimed to describe whether the preoperat ... Full text Link to item Cite

Commensal Urinary Lactobacilli Inhibit Major Uropathogens In Vitro With Heterogeneity at Species and Strain Level.

Journal article Front Cell Infect Microbiol · 2022 The human urinary microbiome is thought to affect the development and progression of urinary tract infections (UTI), particularly recurrent UTIs in aging populations of women. To understand the possible interactions of urinary pathogens with commensal bact ... Full text Link to item Cite

Updating Urinary Microbiome Analyses to Enhance Biologic Interpretation.

Journal article Front Cell Infect Microbiol · 2022 OBJECTIVE: An approach for assessing the urinary microbiome is 16S rRNA gene sequencing, where analysis methods are rapidly evolving. This re-analysis of an existing dataset aimed to determine whether updated bioinformatic and statistical techniques affect ... Full text Link to item Cite

Defining mechanisms of recurrence following apical prolapse repair based on imaging criteria.

Journal article Am J Obstet Gynecol · November 2021 BACKGROUND: Prolapse recurrence after transvaginal surgical repair is common; however, its mechanisms are ill-defined. A thorough understanding of how and why prolapse repairs fail is needed to address their high rate of anatomic recurrence and to develop ... Full text Link to item Cite

The Urinary Microbiome in Postmenopausal Women with Recurrent Urinary Tract Infections.

Journal article J Urol · November 2021 PURPOSE: The etiology of postmenopausal recurrent urinary tract infection (UTI) is not completely known, but the urinary microbiome is thought to be implicated. We compared the urinary microbiome in menopausal women with recurrent UTIs to age-matched contr ... Full text Link to item Cite

Editorial Comment.

Journal article J Urol · November 2021 Full text Link to item Cite

Species-Level Resolution of Female Bladder Microbiota from 16S rRNA Amplicon Sequencing.

Journal article mSystems · October 26, 2021 The human bladder contains bacteria, even in the absence of infection. Interest in studying these bacteria and their association with bladder conditions is increasing. However, the chosen experimental method can limit the resolution of the taxonomy that ca ... Full text Link to item Cite

Impact of Genital Hiatus Size on Anatomic Outcomes After Mesh-Augmented Sacrospinous Ligament Fixation.

Journal article Female Pelvic Med Reconstr Surg · September 1, 2021 OBJECTIVE: Our objective is to compare anatomic outcomes at medium term after mesh-augmented sacrospinous ligament fixation among women categorized by their preoperative and postoperative genital hiatus size. METHODS: We performed a retrospective cohort st ... Full text Link to item Cite

Forming Consensus To Advance Urobiome Research.

Journal article mSystems · August 31, 2021 Urobiome research has the potential to advance the understanding of a wide range of diseases, including lower urinary tract symptoms and kidney disease. Many scientific areas have benefited from early research method consensus to facilitate the greater, co ... Full text Link to item Cite

Does a recent urinary tract infection increase the risk of postprocedure urinary tract infection after onabotulinum toxin a?

Journal article Obstetrical and Gynecological Survey · May 1, 2021 Onabotulinum toxin A (BTX-A) is commonly used as treatment for refractory overactive bladder (OAB) but is associated with postprocedural urinary tract infection (UTI) in up to 35% of cases despite antibiotic prophylaxis. In women with recent UTI, it is unc ... Full text Cite

Benchmarking DNA isolation kits used in analyses of the urinary microbiome.

Journal article Sci Rep · March 17, 2021 The urinary microbiome has been increasingly characterized using next-generation sequencing. However, many of the technical methods have not yet been specifically optimized for urine. We sought to compare the performance of several DNA isolation kits used ... Full text Link to item Cite

Does a Recent Urinary Tract Infection Increase the Risk of Postprocedure Urinary Tract Infection After Onabotulinum Toxin A?

Journal article Female Pelvic Med Reconstr Surg · February 1, 2021 OBJECTIVES: The objective of this study was to evaluate the risk of postprocedure urinary tract infection (UTI) after injection of onabotulinum toxin A (BTX-A) in women who had a UTI within 30 days before procedure. METHODS: This was a retrospective cohort ... Full text Link to item Cite

Evaluation of Host Immune Cellular and Extracellular Matrix Responses to Prolapse Mesh With and Without Tension in a Rat Model.

Journal article Female Pelvic Med Reconstr Surg · February 1, 2021 OBJECTIVES: We sought to determine whether vaginal host immune cellular and extracellular matrix responses are altered in a rat sacrocolpopexy model when lightweight polypropylene mesh is attached on tension versus without tension. METHODS: We performed hy ... Full text Link to item Cite

Polycarbonate Urethane Mesh: A New Material for Pelvic Reconstruction.

Journal article Female Pelvic Med Reconstr Surg · February 1, 2021 OBJECTIVE: Polycarbonate urethane (PCU) is a new biomaterial, and its mechanical properties can be tailored to match that of vaginal tissue. We aimed to determine whether vaginal host immune and extracellular matrix responses differ after PCU versus lightw ... Full text Link to item Cite

The responsiveness and minimally important difference for the Accidental Bowel Leakage Evaluation questionnaire.

Journal article Int Urogynecol J · December 2020 INTRODUCTION AND HYPOTHESIS: We describe the responsiveness and minimally important difference (MID) of the Accidental Bowel Leakage Evaluation (ABLE) questionnaire. METHODS: Women with bowel leakage completed ABLE, Patient Global Impression of Improvement ... Full text Link to item Cite

Outcomes of native tissue transvaginal apical approaches in women with advanced pelvic organ prolapse and stress urinary incontinence.

Journal article Int Urogynecol J · October 2020 INTRODUCTION AND HYPOTHESIS: Limited data exist comparing different surgical approaches in women with advanced vaginal prolapse. This study compared 2-year surgical outcomes of uterosacral ligament suspension (ULS) and sacrospinous ligament fixation (SSLF) ... Full text Link to item Cite

Does Mesh Weight Affect Time to Failure After Robotic-Assisted Laparoscopic Sacrocolpopexy?

Journal article Female Pelvic Med Reconstr Surg · September 2020 OBJECTIVE: The objective of this study was to compare time to anatomic failure after robotic sacrocolpopexy with use of ultralightweight versus heavier weight mesh types. METHODS: We performed a retrospective cohort study of women who underwent robotic sac ... Full text Link to item Cite

A comparison of antibiotic prophylaxis regimens to decrease the risk of post-procedure urinary tract infection after onabotulinum toxin A injection.

Journal article Int Urogynecol J · September 2020 INTRODUCTION AND HYPOTHESIS: To evaluate the risk of post-injection urinary tract infection (UTI) after onabotulinumtoxin A (BTX-A) treatment based on the timing of when antibiotic prophylaxis is started. METHODS: This is a retrospective cohort study of 11 ... Full text Link to item Cite

Diagnosis and Management of Postpartum Pelvic Floor Disorders.

Journal article Obstet Gynecol Clin North Am · September 2020 Pelvic floor disorders are common in the postpartum period. These disorders can significantly affect one's quality of life during a period that is already filled with emotional and physiologic change. This review focuses on the presentation, diagnosis, and ... Full text Link to item Cite

Increasing NIH funding for academic departments of obstetrics and gynecology: a call to action.

Journal article Am J Obstet Gynecol · July 2020 The National Institutes of Health funding for reproductive sciences research, specifically in academic departments of obstetrics and gynecology, is disproportionately low. Research is one of the most important pillars in advancing healthcare. Despite US Co ... Full text Link to item Cite

Accidental Bowel Leakage Evaluation: A New Patient-Centered Validated Measure of Accidental Bowel Leakage Symptoms in Women.

Journal article Dis Colon Rectum · May 2020 BACKGROUND: Questionnaires assessing accidental bowel leakage lack important patient-centered symptoms. OBJECTIVE: We aimed to create a valid measure of accidental bowel leakage symptoms. DESIGN: We previously created a conceptual framework capturing patie ... Full text Link to item Cite

Deciding Our Future: Consensus Conference Summary Report.

Journal article Female Pelvic Med Reconstr Surg · March 2020 OBJECTIVES: There are few quality measures that allow for optimization of care for pelvic organ prolapse (POP). In coordination with the American Urogynecologic Society (AUGS), a prior group agreed upon health care provider-reported data elements that are ... Full text Link to item Cite

Defining the relationship between vaginal and urinary microbiomes.

Journal article Am J Obstet Gynecol · February 2020 BACKGROUND: Although the vaginal and urinary microbiomes have been increasingly well-characterized in health and disease, few have described the relationship between these neighboring environments. Elucidating this relationship has implications for underst ... Full text Link to item Cite

Longitudinal changes in symptom-based female and male LUTS clusters.

Journal article Neurourol Urodyn · January 2020 AIMS: Lower urinary tract symptoms (LUTS) are diverse in type and variable in severity. We examined symptom change within the Symptoms of the Lower Urinary Tract Dysfunction Research Network (LURN) Observational Cohort study identified clusters over time a ... Full text Link to item Cite

The MARBLE Study Protocol: Modulating ApoE Signaling to Reduce Brain Inflammation, DeLirium, and PostopErative Cognitive Dysfunction.

Journal article J Alzheimers Dis · 2020 BACKGROUND: Perioperative neurocognitive disorders (PND) are common complications in older adults associated with increased 1-year mortality and long-term cognitive decline. One risk factor for worsened long-term postoperative cognitive trajectory is the A ... Full text Open Access Link to item Cite

Biomarkers Implicated in Lower Urinary Tract Symptoms: Systematic Review and Pathway Analyses.

Journal article J Urol · November 2019 PURPOSE: Lower urinary tract symptoms are prevalent and burdensome, yet methods to enhance diagnosis and appropriately guide therapies are lacking. We systematically reviewed the literature for human studies of biomarkers associated with lower urinary trac ... Full text Link to item Cite

Are three-day voiding diaries feasible and reliable? Results from the Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN) cohort.

Journal article Neurourol Urodyn · November 2019 AIMS: The aims of this study were to assess the completeness of voiding diaries in a research context and to correlate diary data with patient-reported questionnaires. METHODS: Men and women enrolled in the Symptoms of Lower Urinary Tract Dysfunction Resea ... Full text Link to item Cite

Recruitment and retention: A randomized controlled trial of video-enhanced versus standard consent processes within the E-OPTIMAL study.

Journal article Clin Trials · October 2019 BACKGROUND/AIMS: In this study, we compared two research consent techniques: a standardized video plus usual consent and usual consent alone. METHODS: Individuals who completed 24-month outcomes (completers) in the Operations and Pelvic Muscle Training in ... Full text Link to item Cite

Effect of Behavioral and Pelvic Floor Muscle Therapy Combined With Surgery vs Surgery Alone on Incontinence Symptoms Among Women With Mixed Urinary Incontinence: The ESTEEM Randomized Clinical Trial.

Journal article JAMA · September 17, 2019 IMPORTANCE: Mixed urinary incontinence, including both stress and urgency incontinence, has adverse effects on a woman's quality of life. Studies evaluating treatments to simultaneously improve both components are lacking. OBJECTIVE: To determine whether c ... Full text Link to item Cite

Effect of Vaginal Mesh Hysteropexy vs Vaginal Hysterectomy With Uterosacral Ligament Suspension on Treatment Failure in Women With Uterovaginal Prolapse: A Randomized Clinical Trial.

Journal article JAMA · September 17, 2019 IMPORTANCE: Vaginal hysterectomy with suture apical suspension is commonly performed for uterovaginal prolapse. Transvaginal mesh hysteropexy is an alternative option. OBJECTIVE: To compare the efficacy and adverse events of vaginal hysterectomy with sutur ... Full text Link to item Cite

Controlling faecal incontinence in women by performing anal exercises with biofeedback or loperamide: a randomised clinical trial.

Journal article Lancet Gastroenterol Hepatol · September 2019 BACKGROUND: Well designed, large comparative effectiveness trials assessing the efficacy of primary interventions for faecal incontinence are few in number. The objectives of this study were to compare different combinations of anorectal manometry-assisted ... Full text Open Access Link to item Cite

The Distribution of Post-Void Residual Volumes in People Seeking Care in the Symptoms of Lower Urinary Tract Dysfunction Network Observational Cohort Study With Comparison to Asymptomatic Populations.

Journal article Urology · August 2019 OBJECTIVE: To describe the distribution of post-void residual (PVR) volumes across patients with and without lower urinary tract symptoms (LUTS) and examine relationships between self-reported voiding symptoms, storage symptoms, and PVR. METHODS: PVR and d ... Full text Link to item Cite

A Novel Proteomics Approach to Identify Serum and Urinary Biomarkers and Pathways that Associate with Lower Urinary Tract Symptoms in Men and Women: Pilot Results of the Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN) Study.

Journal article Urology · July 2019 OBJECTIVES: To assess the feasibility of a novel proteomics approach to identify biomarkers associated with lower urinary tract symptoms (LUTS) within serum and urine, because many clinical factors contribute to LUTS in men and women. These factors confoun ... Full text Link to item Cite

Role of β-3 adrenergic receptor polymorphism in overactive bladder.

Journal article Neurourol Urodyn · June 2019 AIMS: Women with overactive bladder (OAB) have a higher frequency of a single-nucleotide polymorphism (SNP) at codon 64 of the β-3 adrenergic receptor gene (ADRB3). Since the SNP results in an amino acid substitution that could theoretically alter receptor ... Full text Link to item Cite

Same-Day Discharge After Robotic-Assisted Sacrocolpopexy.

Journal article Female Pelvic Med Reconstr Surg · 2019 OBJECTIVE: The aim of the study was to compare unplanned postoperative encounters in women discharged same day versus later after robotic-assisted sacrocolpopexy (RA-SCP). METHODS: This is a retrospective cohort study of women who underwent RA-SCP at a ter ... Full text Link to item Cite

Relationship Between Central Obesity, General Obesity, Overactive Bladder Syndrome and Urinary Incontinence Among Male and Female Patients Seeking Care for Their Lower Urinary Tract Symptoms.

Journal article Urology · January 2019 OBJECTIVES: To describe the relationship between metabolic factors and lower urinary tract symptoms, overactive bladder syndrome (OAB) and urinary incontinence (UI). METHODS: Adult male and female patients who presented to a clinician from the symptoms of ... Full text Link to item Cite

Urine RNA Processing in a Clinical Setting: Comparison of 3 Protocols.

Journal article Female Pelvic Med Reconstr Surg · 2019 OBJECTIVE: The objective of this study was to compare quantitative and qualitative RNA extraction results from clinical voided urine samples between 3 commercially available extraction protocols. METHODS: For phase 1, fresh voided urine samples from 10 fem ... Full text Link to item Cite

The urinary microbiome in women with mixed urinary incontinence compared to similarly aged controls.

Journal article Int Urogynecol J · December 2018 INTRODUCTION & HYPOTHESIS: Previous studies have suggested that women with urinary incontinence have an altered urinary microbiome. We hypothesized that the microbiome in women with mixed urinary incontinence (MUI) differed from controls and tested this hy ... Full text Link to item Cite

Bowel function, sexual function, and symptoms of pelvic organ prolapse in women with and without urinary incontinence.

Journal article Neurourol Urodyn · November 2018 AIMS: Bowel symptoms, pelvic organ prolapse, and sexual dysfunction are common, but their frequency among women with lower urinary tract symptoms (LUTS) has not been well described. Our aims were to describe pelvic floor symptoms among women with and witho ... Full text Link to item Cite

Mental Health, Sleep and Physical Function in Treatment Seeking Women with Urinary Incontinence.

Journal article J Urol · October 2018 PURPOSE: We examined how mental health measures, sleep and physical function are associated with the presence and type of urinary incontinence and severity in women seeking treatment for lower urinary tract symptoms. MATERIALS AND METHODS: This baseline cr ... Full text Link to item Cite

Surgical Alteration of Genital Hiatus Size and Anatomic Failure After Vaginal Vault Suspension.

Journal article Obstet Gynecol · June 2018 OBJECTIVE: To compare anatomic outcomes after native tissue vaginal vault suspension among women categorized by their preoperative and 6-week postoperative genital hiatus size. METHODS: We performed a retrospective cohort study in women who underwent nativ ... Full text Link to item Cite

Baseline Lower Urinary Tract Symptoms in Patients Enrolled in LURN: A Prospective, Observational Cohort Study.

Journal article J Urol · April 2018 PURPOSE: We described and compared the frequency and type of lower urinary tract symptoms reported by men and women at the time that they were recruited from urology and urogynecology clinics into the Symptoms of Lower Urinary Tract Dysfunction Research Ne ... Full text Link to item Cite

A genome-scale DNA methylation study in women with interstitial cystitis/bladder pain syndrome.

Journal article Neurourol Urodyn · April 2018 AIMS: To assess the feasibility of using voided urine samples to perform a DNA methylation study in females with interstitial cystitis/bladder pain syndrome (IC/BPS) as compared to age- and race-matched controls. A unique methylation profile could lead to ... Full text Link to item Cite

Metabolites and microbial composition of stool of women with fecal incontinence: Study design and methods.

Journal article Neurourol Urodyn · February 2018 AIMS: This paper aims to report the rationale, design, and the specific methodology of an ongoing nested observational study that will determine the association of the metabolite and microbial composition of stool with fecal incontinence (FI). METHODS: Eli ... Full text Link to item Cite

Vaginal Uterosacral Ligament Suspension: A Retrospective Cohort of Absorbable and Permanent Suture Groups.

Journal article Female Pelvic Med Reconstr Surg · 2018 OBJECTIVE: The aim of this study was to compare anatomic results after vaginal uterosacral ligament suspension with absorbable versus permanent suture. METHODS: We performed a retrospective cohort study of women who underwent vaginal uterosacral ligament s ... Full text Link to item Cite

Refractory urgency urinary incontinence treatment in women: impact of age on outcomes and complications.

Journal article Am J Obstet Gynecol · January 2018 BACKGROUND: Women with refractory urgency urinary incontinence (ie, unresponsive to behavioral and pharmacological interventions) are treated with onabotulinumtoxinA or sacral neuromodulation. OBJECTIVE: The objective of the study was to compare treatment ... Full text Link to item Cite

Correlation of Virtual Reality Simulation and Dry Lab Robotic Technical Skills.

Journal article J Minim Invasive Gynecol · 2018 STUDY OBJECTIVE: To examine whether a set of virtual reality (VR) surgical simulation drills have correlative validity when compared with the validated Robotic Objective Structured Assessment of Technical Skills (R-OSATS) dry lab drills. DESIGN: A prospect ... Full text Link to item Cite

American Urogynecologic Society Prolapse Consensus Conference Summary Report.

Journal article Female Pelvic Med Reconstr Surg · 2018 OBJECTIVES: The 2016 American Urogynecologic Society Prolapse Consensus Conference brought together thought leaders in the field of pelvic organ prolapse (POP). The goal was to identify critical areas of need for future research. This article summarizes th ... Full text Link to item Cite

Improving Postoperative Efficiency: An Algorithm for Expedited Void Trials After Urogynecologic Surgery.

Journal article South Med J · December 2017 OBJECTIVES: To evaluate the relation between voided volume and void trial "success" to create an algorithm that minimizes the need for postvoid residual volume (PVR) assessment in backfill-assisted void trials. METHODS: This article is an ancillary analysi ... Full text Link to item Cite

Perioperative Behavioral Therapy and Pelvic Muscle Strengthening Do Not Enhance Quality of Life After Pelvic Surgery: Secondary Report of a Randomized Controlled Trial.

Journal article Phys Ther · November 1, 2017 BACKGROUND: There is significant need for trials evaluating the long-term effectiveness of a rigorous program of perioperative behavioral therapy with pelvic floor muscle training (BPMT) in women undergoing transvaginal reconstructive surgery for prolapse. ... Full text Link to item Cite

A validated translation of a survey for measuring incontinence knowledge in Chinese-speaking American immigrants.

Journal article Int Urogynecol J · June 2017 INTRODUCTION AND HYPOTHESIS: Urinary incontinence is common amongst Chinese immigrants. These women are a rapidly growing population in the USA who require unique assessment tools due to language barriers. Presently, there are no Chinese language surveys t ... Full text Link to item Cite

Do Mixed-Flora Preoperative Urine Cultures Matter?

Journal article South Med J · June 2017 OBJECTIVES: To determine whether mixed-flora preoperative urine cultures, as compared with no-growth preoperative urine cultures, are associated with a higher prevalence of postoperative urinary tract infections (UTIs). METHODS: This was a retrospective co ... Full text Link to item Cite

Methodology for a vaginal and urinary microbiome study in women with mixed urinary incontinence.

Journal article Int Urogynecol J · May 2017 INTRODUCTION AND HYPOTHESIS: We describe the rationale and methods of a study designed to compare vaginal and urinary microbiomes in women with mixed urinary incontinence (MUI) and similarly aged, asymptomatic controls. METHODS: This paper delineates the m ... Full text Link to item Cite

Crowdsourcing: a valid alternative to expert evaluation of robotic surgery skills.

Journal article Am J Obstet Gynecol · November 2016 BACKGROUND: Robotic-assisted gynecologic surgery is common, but requires unique training. A validated assessment tool for evaluating trainees' robotic surgery skills is Robotic-Objective Structured Assessments of Technical Skills. OBJECTIVE: We sought to a ... Full text Link to item Cite

Methods for a multicenter randomized trial for mixed urinary incontinence: rationale and patient-centeredness of the ESTEEM trial.

Journal article Int Urogynecol J · October 2016 INTRODUCTION AND HYPOTHESIS: Mixed urinary incontinence (MUI) can be a challenging condition to manage. We describe the protocol design and rationale for the Effects of Surgical Treatment Enhanced with Exercise for Mixed Urinary Incontinence (ESTEEM) trial ... Full text Open Access Link to item Cite

Polyethylene Glycol 3350 and Docusate Sodium Compared With Docusate Sodium Alone After Urogynecologic Surgery: A Randomized Controlled Trial.

Journal article Obstet Gynecol · September 2016 OBJECTIVE: To compare time to first bowel movement and additional gastrointestinal outcomes between women receiving polyethylene glycol 3350 (PEG3350) and docusate sodium and docusate sodium alone after urogynecologic surgery. METHODS: Participants receive ... Full text Link to item Cite

Symptoms of Lower Urinary Tract Dysfunction Research Network.

Journal article J Urol · July 2016 PURPOSE: To address gaps in understanding and treating lower urinary tract symptoms, the NIDDK created the Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN). The goals of LURN are to work collaboratively to 1) identify and explain the imp ... Full text Link to item Cite

Microhematuria in Postmenopausal Women: Adherence to Guidelines in a Tertiary Care Setting.

Journal article J Urol · April 2016 PURPOSE: In 2012 the AUA (American Urological Association) released a revision of the asymptomatic microscopic hematuria guidelines. Our study objectives were to assess adherence to these guidelines and describe the prevalence of urinary tract malignancy i ... Full text Link to item Cite

Establishing Benchmarks For Minimum Competence With Dry Lab Robotic Surgery Drills.

Journal article J Minim Invasive Gynecol · 2016 The Robotic Objective Structured Assessment of Technical Skills (R-OSATS) is a previously validated assessment tool that is used to assess 5 standardized inanimate robotic surgery drills. R-OSATS is used to evaluate performance on surgical drills, with sco ... Full text Link to item Cite

Urinary Incontinence and Health-Seeking Behavior Among White, Black, and Latina Women.

Journal article Female Pelvic Med Reconstr Surg · 2016 OBJECTIVE: Fewer than half of women with urinary incontinence (UI) seek care for their condition. Our objective was to qualitatively assess the themes surrounding treatment-seeking behaviors. METHODS: We conducted 12 focus groups with women and, using purp ... Full text Open Access Link to item Cite

Characterizing the Bladder's Response to Onabotulinum Toxin Type A Using a Rat Model.

Journal article Female Pelvic Med Reconstr Surg · 2016 OBJECTIVES: The aim of this study was to characterize the response of the rat bladder neuromuscular system to intramural injection of onabotulinum toxin type A (BoNT/A) over 9 weeks using in vivo cystometry (CMG) and in vitro contractility (IVC). METHODS: ... Full text Link to item Cite

Controlling anal incontinence in women by performing anal exercises with biofeedback or loperamide (CAPABLe) trial: Design and methods.

Journal article Contemp Clin Trials · September 2015 The goals of this trial are to determine the efficacy and safety of two treatments for women experiencing fecal incontinence. First, we aim to compare the use of loperamide to placebo and second, to compare the use of anal sphincter exercises with biofeedb ... Full text Open Access Link to item Cite

Posterior tibial nerve stimulation for the treatment of fecal incontinence: a systematic evidence review.

Journal article Obstet Gynecol Surv · May 2015 IMPORTANCE AND OBJECTIVES: Posterior tibial nerve stimulation (PTNS) is a potential emerging therapy for fecal incontinence (FI). The aim of this study was to systematically review the literature regarding the efficacy of PTNS as a treatment of FI. EVIDENC ... Full text Link to item Cite

What was hot at the ICS meeting 2014?

Journal article Neurourol Urodyn · March 2015 Full text Link to item Cite

Sexual activity and vaginal topography in women with symptomatic pelvic floor disorders.

Journal article J Sex Med · February 2015 INTRODUCTION: Pelvic floor disorders affect vaginal anatomy and may affect sexual function. AIMS: The aims of this study were to explore the relationship between vaginal anatomy and sexual activity in women with symptomatic pelvic floor disorders and to as ... Full text Link to item Cite

Barriers to urinary incontinence care seeking in White, Black, and Latina women.

Journal article Female Pelvic Med Reconstr Surg · 2015 OBJECTIVE: We compared barriers to urinary incontinence (UI) healthcare seeking between white, black, and Latina women. METHODS: This is a cross-sectional study using a convenience sample of white, black, and Latina women. Women completed the Barriers to I ... Full text Open Access Link to item Cite

Mesh sacrocolpopexy compared with native tissue vaginal repair: a systematic review and meta-analysis.

Journal article Obstet Gynecol · January 2015 OBJECTIVE: To systematically review outcomes after mesh sacrocolpopexy compared with native tissue vaginal repairs in women with apical prolapse. DATA SOURCES: We searched MEDLINE, EMBASE, the Cochrane Central Register of Controlled Trials, and ClinicalTri ... Full text Link to item Cite

Optimizing Urine Processing Protocols for Protein and Metabolite Detection.

Journal article J Proteomics Bioinform · 2015 BACKGROUND: In urine, factors such as timing of voids, and duration at room temperature (RT) may affect the quality of recovered protein and metabolite data. Additives may aid with detection, but can add more complexity in sample collection or analysis. We ... Link to item Cite

In reply.

Journal article Obstet Gynecol · October 2014 Full text Link to item Cite

Does concomitant anterior/apical repair during midurethral sling improve the overactive bladder component of mixed incontinence?

Journal article Int Urogynecol J · September 2014 INTRODUCTION AND HYPOTHESIS: Midurethral sling (MUS) can improve overactive bladder (OAB) symptoms. It is unclear if anterior/apical prolapse (AA) repair provides additional benefit. We hypothesized that women with mixed urinary incontinence (MUI) experien ... Full text Link to item Cite

Perceptions about female urinary incontinence: a systematic review.

Journal article Int Urogynecol J · July 2014 INTRODUCTION AND HYPOTHESIS: Perceptions about urinary incontinence (UI) may have a differential impact on treatment-seeking behaviors. Thus, we aimed to systematically review perceptions regarding UI in women of different racial and ethnic populations. ME ... Full text Link to item Cite

Validity and reliability of the robotic Objective Structured Assessment of Technical Skills.

Journal article Obstet Gynecol · June 2014 OBJECTIVE: Objective Structured Assessments of Technical Skills have been developed to measure the skill of surgical trainees. Our aim was to develop an Objective Structured Assessments of Technical Skills specifically for trainees learning robotic surgery ... Full text Link to item Cite

Symptom outcomes important to women with anal incontinence: a conceptual framework.

Journal article Obstet Gynecol · May 2014 OBJECTIVE: To develop a framework that describes the most important symptom outcomes for anal incontinence treatment from the patient perspective. METHODS: A conceptual framework was developed by the Pelvic Floor Disorders Network based on four semistructu ... Full text Link to item Cite

Pre-operative urodynamics in women with stress urinary incontinence increases physician confidence, but does not improve outcomes.

Journal article Neurourol Urodyn · March 2014 AIMS: To determine if pre-operative urodynamic testing (UDS) affects physicians' diagnostic confidence and if physician confidence affects treatment outcomes at 1 year. METHODS: The Value of Urodynamic Evaluation (ValUE) trial randomized 630 women with pre ... Full text Link to item Cite

A model for predicting the risk of de novo stress urinary incontinence in women undergoing pelvic organ prolapse surgery.

Journal article Obstet Gynecol · February 2014 OBJECTIVE: To construct and validate a prediction model for estimating the risk of de novo stress urinary incontinence (SUI) after vaginal pelvic organ prolapse (POP) surgery and compare it with predictions using preoperative urinary stress testing and exp ... Full text Open Access Link to item Cite

Oral antibiotics to prevent postoperative urinary tract infection: a randomized controlled trial.

Journal article Obstet Gynecol · January 2014 OBJECTIVE: To evaluate whether nitrofurantoin prophylaxis prevents postoperative urinary tract infection (UTI) in patients receiving transurethral catheterization after pelvic reconstructive surgery. METHODS: In a randomized, double-blind, placebo-controll ... Full text Link to item Cite

Commentary on 'Sex after surgery-what should we tell our patients?'

Journal article BJOG an International Journal of Obstetrics and Gynaecology · January 1, 2014 Full text Cite

Clinical challenges in the management of vaginal prolapse.

Journal article Int J Womens Health · 2014 Pelvic organ prolapse is highly prevalent, and negatively affects a woman's quality of life. Women with bothersome prolapse may be offered pessary management or may choose to undergo corrective surgery. In choosing the most appropriate surgical procedure, ... Full text Link to item Cite

Is postoperative bowel function related to posterior compartment prolapse repair?

Journal article Female Pelvic Med Reconstr Surg · 2014 OBJECTIVES: This study aimed to assess how posterior repair (PR) affects change in bowel function in women undergoing anterior/apical surgery for prolapse. METHODS: We performed a retrospective cohort study of women undergoing prolapse surgery. Our 2 cohor ... Full text Link to item Cite

Perioperative anticholinergic medications and risk of catheterization after urogynecologic surgery.

Journal article Female Pelvic Med Reconstr Surg · 2014 OBJECTIVE: This study aimed to examine how anticholinergic medication exposure affects the risk of failed postoperative void trial (VT) in women undergoing urogynecologic surgery. METHODS: We conducted a retrospective cohort study of women undergoing outpa ... Full text Link to item Cite

How does site of pelvic organ prolapse repair affect overactive bladder symptoms?

Journal article Female Pelvic Med Reconstr Surg · 2014 OBJECTIVES: To assess how site of pelvic organ prolapse repair affects overactive bladder (OAB) symptoms, we compared change in OAB symptoms in women undergoing isolated anterior/apical (AA) repair versus isolated posterior (P) repair. METHODS: This is a r ... Full text Link to item Cite

Psychosocial factors related to the use of InterStim® for the treatment of refractory overactive bladder.

Journal article Female Pelvic Med Reconstr Surg · 2014 OBJECTIVES: Sacral neuromodulation is a well-established treatment of refractory overactive bladder (OAB). Although literature exists on the psychosocial impact of other implanted medical devices, data do not exist for InterStim therapy. We aim to evaluate ... Full text Link to item Cite

Minimum important differences for scales assessing symptom severity and quality of life in patients with fecal incontinence.

Journal article Female Pelvic Med Reconstr Surg · 2014 OBJECTIVES: The objective of this study was to estimate the minimum important difference (MID) for the Fecal Incontinence Severity Index (FISI), the Colorectal-Anal Distress Inventory (CRADI) scale of the Pelvic Floor Distress Inventory, the Colorectal-Ana ... Full text Open Access Link to item Cite

Impact of staged InterStim implantation on the postoperative activities of daily living and pain.

Journal article Int Urogynecol J · July 2013 OBJECTIVES: To evaluate the short-term effects of staged InterStim implantation on activities of daily living (ADL) and pain. METHODS: This prospective study assessed women undergoing staged InterStim implantation. The Older Americans Resources and Service ... Full text Link to item Cite

Comparing the risk of urethrolysis for the treatment of voiding dysfunction between two retropubic mesh slings: a case-control study.

Journal article Int Urogynecol J · April 2013 INTRODUCTION AND HYPOTHESIS: Long-term outcome data exist with Gynecare TVT tension-free support for incontinence (TVT), yet few comparisons have been made to newer retropubic sling delivery systems, especially with regards to urethrolysis for postoperativ ... Full text Link to item Cite

Vaginal prolapse recurrence after uterosacral ligament suspension in normal-weight compared with overweight and obese women.

Journal article Obstet Gynecol · March 2013 OBJECTIVE: To compare recurrent prolapse after vaginal uterosacral ligament suspension in normal-weight compared with overweight or obese women. METHODS: We performed a retrospective cohort study of the risk of recurrent prolapse after uterosacral ligament ... Full text Link to item Cite

Nonsurgical management of heavy menstrual bleeding: a systematic review.

Journal article Obstet Gynecol · March 2013 OBJECTIVE: To compare the effectiveness of nonsurgical abnormal uterine bleeding treatments for bleeding control, quality of life (QOL), pain, sexual health, patient satisfaction, additional treatments needed, and adverse events. DATA SOURCES: MEDLINE, Coc ... Full text Link to item Cite

Postoperative management and restrictions for female pelvic surgery: a systematic review.

Journal article Int Urogynecol J · February 2013 INTRODUCTION AND HYPOTHESIS: We sought to systematically review the literature regarding the effect of postoperative restrictions on clinical outcomes after pelvic surgery. METHODS: English-language articles were identified by a MEDLINE and Cochrane Centra ... Full text Link to item Cite

Sling revision/removal for mesh erosion and urinary retention: long-term risk and predictors.

Journal article Am J Obstet Gynecol · January 2013 OBJECTIVE: The objective of the study was to estimate the long-term risk of sling revision/removal after an initial sling and to assess indications (mesh erosion and urinary retention) and predictors of sling revision/removal. STUDY DESIGN: Using a populat ... Full text Link to item Cite

Obesity as a risk for the recurrence of anterior vaginal wall prolapse after anterior colporrhaphy.

Journal article J Reprod Med · 2013 OBJECTIVE: To determine whether obese body mass index is associated with the recurrence of anterior vaginal wall prolapse after anterior colporrhaphy. STUDY DESIGN: We conducted a retrospective cohort study of the risk of recurrent anterior prolapse 6 mont ... Link to item Cite

Do urodynamic parameters predict persistent postoperative stress incontinence after midurethral sling? A systematic review.

Journal article Int Urogynecol J · July 2012 Featured Publication INTRODUCTION AND HYPOTHESIS: It is unclear whether preoperative urodynamic study (UDS) values are predictive of outcomes after midurethral sling. MATERIALS AND METHODS: We systematically reviewed multiple databases from January 1989 to October 2011 for Eng ... Full text Link to item Cite

Long-term outcomes after stress urinary incontinence surgery.

Journal article Obstet Gynecol · July 2012 OBJECTIVES: To compare the long-term risk of repeat stress urinary incontinence (SUI) surgery after different types of initial SUI surgery and to identify predictors of time to repeat SUI surgery in a large, population-based cohort. METHODS: We used de-ide ... Full text Link to item Cite

Symptomatic and anatomic 1-year outcomes after robotic and abdominal sacrocolpopexy.

Journal article Am J Obstet Gynecol · May 2012 Featured Publication OBJECTIVE: The purpose of this study was to compare symptomatic and anatomic outcomes 1 year after robotic vs abdominal sacrocolpopexy. STUDY DESIGN: Our retrospective cohort study compared women who underwent robotic sacrocolpopexy (RSC) with 1 surgeon to ... Full text Link to item Cite

Treatment for urinary tract infection after midurethral sling: a retrospective study comparing patients who receive short-term postoperative catheterization and patients who pass a void trial on the day of surgery.

Journal article Female Pelvic Med Reconstr Surg · 2012 Featured Publication INTRODUCTION: This is a retrospective cohort study comparing the risk of treatment for postoperative urinary tract infection (UTI) in patients who receive short-term postoperative catheterization versus those who pass a void trial on the day of surgery aft ... Full text Link to item Cite

Does obesity impact the success of an InterStim test phase for the treatment of refractory urge urinary incontinence in female patients?

Journal article Female Pelvic Med Reconstr Surg · 2012 OBJECTIVES: Some providers believe obesity may be a relative contraindication for InterStim; however, the relationship between obesity and treatment outcome has not been evaluated. Our objectives were to compare the test phase (stage 1) success and complic ... Full text Link to item Cite

Sexual function after vaginal versus nonvaginal prolapse surgery.

Journal article Female Pelvic Med Reconstr Surg · 2012 OBJECTIVES: To compare sexual function based on the Pelvic Organ Prolapse/Urinary Incontinence Sexual Function Questionnaire (PISQ) in women who underwent vaginal versus nonvaginal surgery for prolapse. METHODS: This was a prospective cohort study of women ... Full text Link to item Cite

Shifts in national rates of inpatient prolapse surgery emphasize current coding inadequacies.

Journal article Female Pelvic Med Reconstr Surg · July 2011 Featured Publication OBJECTIVE: : This study aimed to assess national rates, types, and routes of inpatient surgery for pelvic organ prolapse in the United States in 1998 compared to those in 2007. METHODS: : We used the 1998 and 2007 Nationwide Inpatient Sample, which represe ... Full text Link to item Cite

Lead migration after sacral neuromodulation: surgical revision in fascial versus tined anchoring systems.

Journal article Int Urogynecol J · April 2011 Featured Publication INTRODUCTION AND HYPOTHESIS: Our objective was to compare risk of surgical revision after sacral neuromodulator lead migration based on the type of anchoring system. METHODS: We performed a retrospective cohort study of patients receiving sacral neuromodul ... Full text Link to item Cite

Duty hour restrictions, ambulatory experience, and surgical procedural volume in obstetrics and gynecology.

Journal article J Grad Med Educ · December 2010 BACKGROUND: Prior studies of resident experience in gynecology looked only at the year before and after adoption of ACGME duty hour standards. This study sought to determine whether procedure volume differed after completion of a 4-year residency training ... Full text Link to item Cite

Neural entrapment during uterosacral ligament suspension: an anatomic study of female cadavers.

Journal article Obstet Gynecol · September 2010 Featured Publication OBJECTIVE: To describe retroperitoneal neural structures at risk during uterosacral ligament suspension and to estimate risk of neural injury based on uterosacral ligament suspension suture placement technique. METHODS: Uterosacral ligament suspension was ... Full text Link to item Cite

The questionnaire for urinary incontinence diagnosis (QUID): validity and responsiveness to change in women undergoing non-surgical therapies for treatment of stress predominant urinary incontinence.

Journal article Neurourology and urodynamics · June 1, 2010 The Questionnaire for Urinary Incontinence Diagnosis (QUID), a 6-item urinary incontinence (UI) symptom questionnaire, was developed and validated to distinguish stress and urge UI. This study's objective was to evaluate QUID validity and responsiveness wh ... Cite

The questionnaire for urinary incontinence diagnosis (QUID): validity and responsiveness to change in women undergoing non-surgical therapies for treatment of stress predominant urinary incontinence.

Journal article Neurourol Urodyn · June 2010 Featured Publication AIMS: The Questionnaire for Urinary Incontinence Diagnosis (QUID), a 6-item urinary incontinence (UI) symptom questionnaire, was developed and validated to distinguish stress and urge UI. This study's objective was to evaluate QUID validity and responsiven ... Full text Link to item Cite

Cost-minimization analysis of robotic-assisted, laparoscopic, and abdominal sacrocolpopexy.

Journal article J Minim Invasive Gynecol · 2010 Featured Publication STUDY OBJECTIVE: To perform a cost-minimization analysis comparing robotic-assisted, laparoscopic, and abdominal sacrocolpopexy. DESIGN: Cost-minimization analysis using a micro-costing approach (Canadian Task Force classification III). MEASUREMENTS AND MA ... Full text Link to item Cite

Efficacy and adverse events of sacral nerve stimulation for overactive bladder: A systematic review.

Journal article Neurourol Urodyn · 2010 Featured Publication AIMS: To systematically review the literature regarding efficacy and adverse events of sacral nerve stimulation (SNS) via the InterStim device for treatment of women with refractory overactive bladder (OAB). METHODS: We searched MEDLINE, Embase, Web of Sci ... Full text Link to item Cite

Cost-effectiveness of sacral neuromodulation versus intravesical botulinum A toxin for treatment of refractory urge incontinence.

Journal article J Urol · December 2009 Featured Publication PURPOSE: We determined the cost-effectiveness of sacral neuromodulation vs intravesical botulinum toxin A for the treatment of refractory urge incontinence. MATERIALS AND METHODS: We developed a Markov decision model using a societal perspective to compare ... Full text Link to item Cite

Cost-effectiveness of botulinum toxin a versus anticholinergic medications for idiopathic urge incontinence.

Journal article J Urol · May 2009 Featured Publication PURPOSE: We assessed the cost-effectiveness of botulinum toxin A injection compared to anticholinergic medications for the treatment of idiopathic urge incontinence. MATERIALS AND METHODS: A Markov decision analysis model was developed to compare the costs ... Full text Link to item Cite

Objective structured assessment of technical skills for repair of fourth-degree perineal lacerations.

Journal article Am J Obstet Gynecol · December 2008 Featured Publication OBJECTIVE: The objective of this study was to assess the reliability and validity of an objective structured assessment of technical skills (OSATS) for repair of fourth-degree obstetric lacerations on a surgical model. STUDY DESIGN: Three blinded judges re ... Full text Link to item Cite

Short-term outcomes of robotic sacrocolpopexy compared with abdominal sacrocolpopexy.

Journal article Obstet Gynecol · December 2008 Featured Publication OBJECTIVE: To compare short-term outcomes of robotic sacrocolpopexy with abdominal sacrocolpopexy for vaginal vault prolapse. METHODS: We conducted a retrospective cohort study comparing robotic to abdominal sacrocolpopexy with placement of permanent mesh. ... Full text Link to item Cite

Do we practice what we preach? A qualitative assessment of resident-preceptor interactions for adherence to evidence-based practice.

Journal article J Eval Clin Pract · October 2008 BACKGROUND: Evidence-based medicine (EBM) is important in training doctors for high-quality care. Yet little is known about whether ambulatory precepting incorporates the concepts and principles of EBM. METHODS: The authors observed and audiotaped 95 inter ... Full text Link to item Cite

How do doctors use information in real-time? A qualitative study of internal medicine resident precepting.

Journal article J Eval Clin Pract · October 2007 BACKGROUND: Despite the importance of evidence-based medicine in medical education, little observational research exists on how doctors-in-training seek and use evidence from information resources in ambulatory care. OBJECTIVE: To describe information exch ... Full text Link to item Cite

Vesicovaginal fistula due to an unreported foreign body in an adolescent.

Journal article J Pediatr Adolesc Gynecol · August 2007 Featured Publication BACKGROUND: In the United States, vesico-vaginal fistula formation is most commonly associated with prior gynecologic surgery, and only rarely with severe pressure necrosis. CASE: A 16-year-old girl presented with continuous urinary leakage and malodorous ... Full text Link to item Cite

Textbook recommendations for preventing and treating perineal injury at vaginal delivery.

Journal article Obstet Gynecol · February 2006 Featured Publication OBJECTIVE: To assess general obstetrics textbooks regarding the quality and quantity of information about perineal injury at vaginal delivery. METHODS: An obstetrics and gynecology resident, a perinatologist, and a urogynecologist evaluated 7 obstetrics te ... Full text Link to item Cite

Guidelines on using guidelines.

Journal article BJOG · December 2002 Full text Link to item Cite

Structure of the human gene (COX6A2) for the heart/muscle isoform of cytochrome c oxidase subunit VIa and its chromosomal location in humans, mice, and cattle.

Journal article Genomics · May 15, 1997 We have mapped the gene for the heart/muscle isoform of cytochrome c oxidase (COX) subunit VIa in three mammalian species and isolated the human COX6AH gene (HGMW-approved symbol COX6A2). The bovine gene was mapped by somatic cell hybrid mapping panels to ... Full text Link to item Cite

Evidence for response set effects in structured research interviews.

Journal article J Nerv Ment Dis · July 1996 The Addiction Severity Index and NIMH Diagnostic Interview Schedule data of 20 methadone-maintained subjects with "fake bad" invalid profiles on the Personality Assessment Inventory, 15 methadone-maintained subjects with "fake good" invalid profiles, and 1 ... Full text Link to item Cite