Scholars@Duke
Nenad Bursac

Nenad Bursac

Professor of Biomedical Engineering
Biomedical Engineering
Duke Box 90281, Durham, NC 27708-0281
ORCID iDhttps://orcid.org/0000-0002-5688-6061
CIEMAS 1141, Durham, NC 27708

Scholarly Works - Conferences

Abstract 4359395: Cardiac Function is Preserved in a Tissue-Engineered Model of LGMD2B

Conference Circulation · November 4, 2025 Background: Loss of dysferlin results in the rare, currently untreatable muscular dystrophy known as Limb Girdle Muscular Dystrophy 2B (LGMD2B). In LGMD2B mice, skeletal muscle undergo ... Full text Cite

Abstract 4358648: Prokaryotic Voltage-Gated Sodium Channel (BacNav) Gene Therapy Restores Contractile and Electrical Function in a Rat Model of Chronic Ischemia-Reperfusion Heart Failure

Conference Circulation · November 4, 2025 Introduction: Following infarction, heart often undergoes pathological remodeling and dysregulation of sodium and calcium homeostasis, predisposing patients to heart failure and arrhyt ... Full text Cite

Abstract 4369523: A Novel Bioreactor to Model Time-Varying Mechanical Preload and Afterload in Engineered Cardiac Tissues

Conference Circulation · November 4, 2025 Introduction: During postnatal development, the heart undergoes continuous adaptation to mechanical loads—primarily preload (stretch experienced during chamber filling) and afterload ( ... Full text Cite

Abstract 4364390: Development of an In Vitro Model of Functionally Innervated Human Myocardium

Conference Circulation · November 4, 2025 Introduction: Cardiac sympathetic innervation plays important roles in regulation of heart rate, contractility, and conduction, as well as postnatal maturation and injury response. How ... Full text Cite

Abstract P2164: Expression Of Engineered Bacterial Sodium Channel Improves Cardiomyocyte Contractility

Conference Circulation Research · August 4, 2023 Introduction: Our recent studies in non-human primates have demonstrated adeno-associated virus (AAV) delivery of prokaryotic sodium channel (BacNa v ) can ... Full text Cite

3D Tissue-engineered Model of Pressure-overload Induced Cardiac Fibrosis

Conference TISSUE ENGINEERING PART A · December 1, 2017 Link to item Cite

Skeletal Muscle-Macrophage Platform for Modeling Tissue Regeneration

Conference TISSUE ENGINEERING PART A · December 1, 2017 Link to item Cite

In Vitro Bioengineered Model for Studies of Human Muscle Regeneration

Conference TISSUE ENGINEERING PART A · December 1, 2017 Link to item Cite

PGE - Product generation engineering - Case study of the dual mass flywheel

Conference Proceedings of International Design Conference Design · January 1, 2016 Cite

STIM1-Ca2+ signaling modulates automaticity of the mouse sinoatrial node.

Conference Proc Natl Acad Sci U S A · October 13, 2015 Cardiac pacemaking is governed by specialized cardiomyocytes located in the sinoatrial node (SAN). SAN cells (SANCs) integrate voltage-gated currents from channels on the membrane surface (membrane clock) with rhythmic Ca(2+) release from internal Ca(2+) s ... Full text Link to item Cite

Engineering Regenerative Skeletal Muscle Tissues

Conference TISSUE ENGINEERING PART A · September 1, 2015 Link to item Cite

Novel In Vitro Exercise Model of Engineered Human Skeletal Muscle

Conference TISSUE ENGINEERING PART A · September 1, 2015 Link to item Cite

BIOENGINEERED HUMAN MUSCLE FOR PHYSIOLOGICAL STUDIES AND DISEASE MODELING

Conference MOLECULAR GENETICS AND METABOLISM · March 1, 2015 Link to item Cite

The role restitution in pacing induced spiral wave acceleration

Conference 2006 28TH ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY, VOLS 1-15 · January 1, 2006 Link to item Cite