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Miguel Angelo L. Nicolelis

Professor Emeritus of Neurobiology
Neurobiology
Gsrbii 210 Research Drive, Box 103905 Room 4028, Durham, NC 27710
Gsrbii 210 Research Drive, Box 103905 Room 4028, Durham, NC 27710

Scholarly Works - Book sections


Frontiers in neuroscience

Book section · April 26, 2012 Cite

Sleep and Sleep States: Network Reactivation

Book section · January 1, 2009 Network reactivation is a key neural property for the generation of innate and learned behavior. The activation of recurrent anatomical loops underlies the different rhythms produced by the brain, characterizing the distinct global states that comprise wak ... Full text Cite

Conceptual and technical approaches to human neural ensemble recordings

Book section · January 1, 2007 The ability to perform either multineuron or local field/EEG recordings from the nervous system is a critical requirement to develop a new generation of neuroprosthetics that can sense the brain’s intent for action (Nicolelis 2001, 2003). This form of sens ... Cite

State-of-the-art microwire array design for chronic neural recordings in behaving animals

Book section · January 1, 2007 Over the last two decades, many laboratories around the world have started to rely on microelectrode arrays formed by ne microwires, organized in different geometrical congurations, to chronically record the extracellular activity of populations of individ ... Cite

Building brain-machine interfaces to restore neurological functions

Book section · January 1, 2007 Modern research on brain-machine interfaces (BMI) is a highly multidisciplinary field that has been developing at a stunning pace since the first experiment conducted 8 years ago that demonstrated direct control of a robotic manipulator by ensembles of neu ... Cite

Neural ensemble recordings from central gustatory-reward pathways in awake and behaving animals

Book section · January 1, 2007 The mammalian gustatory system participates in the detection and discrimination of intraoral stimuli, allowing for the selection of nutrients and rejection of toxic compounds. However, the sensory percept of a substance that is placed in the mouth does not ... Cite

Neuroprosthetics and clinical realization of brain-machine interfaces

Book section · January 1, 2004 Neuroprosthetics encompasses a wide variety of interfaces with the nervous system, usually considered in the context of clinical abnormalities or disease. The concept stems from clinical concerns about functional independence and integration of individuals ... Cite

Pre-ictal seizure detection and demand treatment strategies for epilepsy

Book section · January 1, 2004 Mechanisms of epilepsy have been explored through a variety of animal models as well as detailed human studies, for more than 70 years.1-3 Through the animal models, a large number of contributing factors leading to epilepsy have been demonstrated, includi ... Cite

Advances in brain-machine interfaces

Book section · January 1, 2004 Throughout history, the introduction of new technologies has significantly impacted human life in many different ways. Until now, however, each new artificial device or tool designed to enhance human motor, sensory, or cognitive capabilities has relied on ... Cite

Neuronal reverberation and the consolidation of new memories across the wake-sleep cycle

Book section · January 1, 2004 In mammals and birds, long episodes of nondreaming sleep (slow-wave sleep, SW) are followed by short episodes of dreaming sleep (rapid-eye-movement sleep, REM). ... Cite

Integration of behavior and timing: Anatomically separate systems or distributed processing?

Book section · January 1, 2003 With the recent development of powerful methods to study brain-behavior relations, the study of interval timing has rapidly shifted from primarily behavioral analyses elucidating the psychological constructs of timing to investigations aimed at identifying ... Cite

Designing a brain- machine interface for neuroprosthetic control

Book section · January 1, 2000 There are roughly four major subassemblies of a brain derived neuroprosthetic control device: (1) the electrodes subassembly, (2) signal conditioning subassembly, (3) signal acquisition subassembly, and (4) transmitter subassemblies (Table 6.1). Notably ab ... Cite

Brain control of sensorimotor prostheses

Book section · January 1, 2000 The introduction to this volume outlines the possibilities inherent in utilizing electronic interfaces with the brain to alleviate problems of paralysis, such as that caused by spinal cord injury. The possibility of using electroencephalographic recordings ... Cite