Overview
Dr. Nicole Pelot is a biomedical engineer at Duke University, conducting neural engineering research with a focus on neuromodulation of the autonomic nervous system, including anatomical studies, extensive development of computational methods to build anatomically realistic models of nerve stimulation, optimization methods to develop improved therapies, and in vivo electrophysiology. Nikki leads a team of researchers at Duke and works closely with collaborators at other institutions.
She earned her Bachelor's of Electrical Engineering and Bachelor's of Science (Physics) at Dalhousie University (Halifax, NS, Canada). She then earned her PhD in Biomedical Engineering at Duke University (Durham, NC, USA).
In addition to scientific excellence, she continually works to improve her academic project management and mentorship skills. Outside of research, Nikki is a dancer, yogi, and backpacker.
Current Appointments & Affiliations
Recent Publications
Application of kilohertz-frequency block to mitigate off-target motor effects of vagus nerve stimulation in swine
Preprint · April 14, 2025 Full text CiteGuidance for sharing computational models of neural stimulation: from project planning to publication.
Journal Article Journal of neural engineering · March 2025 Objective. Sharing computational models offers many benefits, including increased scientific rigor during project execution, readership of the associated paper, resource usage efficiency, replicability, and reusability. In recognition of the growing ... Full text CiteHighly efficient modeling and optimization of neural fiber responses to electrical stimulation.
Journal Article Nature communications · August 2024 Peripheral neuromodulation has emerged as a powerful modality for controlling physiological functions and treating a variety of medical conditions including chronic pain and organ dysfunction. The underlying complexity of the nonlinear responses to electri ... Full text CiteRecent Grants
Optimized Electrical Block of Peripheral Nerves
ResearchResearch Scientist · Awarded by National Institute of Neurological Disorders and Stroke · 2023 - 2027A Rational Engineering Design Approach to Minimizing the Off-Target Effects of Baroreceptor Activation Therapy
ResearchPrincipal Investigator · Awarded by University of Wisconsin - Madison · 2022 - 2026Mapping the Autonomic Pathways across 100 Human Vagus Nerves within a Demographically Representative Sample (MAP-100VN)
ResearchPrincipal Investigator · Awarded by Case Western Reserve University · 2022 - 2025View All Grants