Overview
Current Appointments & Affiliations
Associate Professor of Ophthalmology
·
2021 - Present
Ophthalmology,
Clinical Science Departments
Recent Publications
Physiological activation of liver X receptor provides protection against ocular inflammation in uveitic glaucoma.
Journal Article Biochimica et biophysica acta. Molecular basis of disease · January 2025 Virus-induced trabeculitis is considered a significant cause of uveitic glaucoma, being marked by a sudden increase in intraocular pressure and relatively mild inflammation in the anterior chamber of the eye. In previous proteome analyses of aqueous humor ... Full text CiteAnkyrin-B is required for the establishment and maintenance of lens cytoarchitecture, mechanics and clarity.
Journal Article J Cell Sci · December 15, 2024 The transparent ocular lens is essential for vision because it focuses light onto the retina. Despite recognition of the importance of its unique cellular architecture and mechanical properties, the molecular mechanisms governing these attributes remain el ... Full text Link to item CiteDysregulation of septin cytoskeletal organization in the trabecular meshwork contributes to ocular hypertension.
Journal Article JCI Insight · December 6, 2024 Ocular hypertension, believed to result partly from increased contractile activity, cell adhesive interactions, and stiffness within the trabecular meshwork (TM), is a major risk factor for glaucoma, a leading cause of blindness. However, the identity of m ... Full text Link to item CiteRecent Grants
Identification of proteins localized to photoreceptor connecting cilium
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2024 - 2026Identification of novel contributors to retinitis pigmentosa using metabolic and proteomic approaches
ResearchPrincipal Investigator · Awarded by University of North Carolina - Chapel Hill · 2021 - 2024Deciphering the local effect of glaucoma risk factors on axonal mitoproteome
ResearchCollaborator · Awarded by BrightFocus Foundation · 2021 - 2024View All Grants
Education, Training & Certifications
Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry (Russia) ·
1986
Ph.D.
Lomonosov Moscow State Universty (Russia) ·
1978
B.S.