Noraguadalupe Ramirez

My research interest includes understanding host-pathogen interactions, specifically how the host cell state can influence viral fate and how viruses can reshape host cell state. I completed my molecular microbiology PhD in the lab of Dr. Iván D’Orso at UT Southwestern Medical Center. During my PhD, I identified a previously undescribed host factor that could tune T cell resting to active state transition and promotes latent HIV-1 reactivation. Currently, in Dr. Carolyn Coyne’s lab here at Duke, my research is focused on studying how enteroviruses can reshape the host cellular and transcriptional landscape to elude the innate anti-viral response using enteroids, 3-D organoid models of the gut.