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Oyindamola Adefisayo

Postdoctoral Associate
Molecular Genetics and Microbiology
270 Jones, Box 3054, Durham, NC 27710
270 Jones BX 3054, 207 Research Drive, Durham, NC 27710

Selected Publications


Distinctive roles of translesion polymerases DinB1 and DnaE2 in diversification of the mycobacterial genome through substitution and frameshift mutagenesis

Journal Article Nature Communications · August 2, 2022 AbstractAntibiotic resistance of Mycobacterium tuberculosis is exclusively a consequence of chromosomal mutations. Translesion synthesis (TLS) is a widely conserved mechanism of DNA damage toleran ... Full text Cite

Division of labor between SOS and PafBC in mycobacterial DNA repair and mutagenesis

Journal Article Nucleic Acids Research · December 16, 2021 AbstractDNA repair systems allow microbes to survive in diverse environments that compromise chromosomal integrity. Pathogens such as Mycobacterium tuberculosis must contend with the genotoxic host environme ... Full text Cite

Mycobacterial Mutagenesis and Drug Resistance Are Controlled by Phosphorylation- and Cardiolipin-Mediated Inhibition of the RecA Coprotease.

Journal Article Mol Cell · October 4, 2018 Infection with Mycobacterium tuberculosis continues to cause substantial human mortality, in part because of the emergence of antimicrobial resistance. Antimicrobial resistance in tuberculosis is solely the result of chromosomal mutations that modify drug ... Full text Link to item Cite