Patricia Gripka Moorman

Journal article J Clin Oncol · November 20, 2013 Featured Publication PURPOSE: To estimate the risks of ovarian cancer and breast cancer associated with oral contraceptive (OC) use among women at elevated risk owing to mutations in BRCA1/2 or a strong family history. METHODS: We searched PubMed, Embase, the Cochrane Database ... Full text Link to item Cite

Oral contraceptive pills as primary prevention for ovarian cancer: a systematic review and meta-analysis.

Journal article Obstet Gynecol · July 2013 Featured Publication OBJECTIVE: To estimate the overall reduction in ovarian cancer risk associated with the use of oral contraceptive pills (OCPs) and whether reduction in risk is affected by specifics of OCP use, such as formulation or duration of use. DATA SOURCES: We searc ... Full text Link to item Cite

Comparison of characteristics of fibroids in African American and white women undergoing premenopausal hysterectomy.

Journal article Fertil Steril · March 1, 2013 Featured Publication OBJECTIVE: To compare pathologic characteristics and epidemiologic risk factors for uterine fibroids in African American and white women undergoing hysterectomy. DESIGN: Cross-sectional analysis of women undergoing premenopausal hysterectomy. SETTING: Two ... Full text Link to item Cite

Effect of hysterectomy with ovarian preservation on ovarian function.

Journal article Obstet Gynecol · December 2011 Featured Publication OBJECTIVE: To prospectively estimate the risk for earlier ovarian failure among women undergoing hysterectomy with ovarian preservation, as compared with women of similar age without hysterectomy. METHODS: A prospective cohort study was conducted among wom ... Full text Link to item Cite

Evaluation of established breast cancer risk factors as modifiers of BRCA1 or BRCA2: a multi-center case-only analysis.

Journal article Breast Cancer Res Treat · November 2010 Featured Publication The incomplete penetrance of mutations in BRCA1 and BRCA2 suggests that some combination of environmental and genetic factors modifies the risk of breast cancer in mutation carriers. This study sought to identify possible interactions between established b ... Full text Link to item Cite

Ovarian cancer risk factors in African-American and white women.

Journal article Am J Epidemiol · September 1, 2009 Featured Publication Ovarian cancer is the most lethal gynecologic malignancy in both African-American and white women. Although prevalences of many ovarian cancer risk factors differ markedly between African Americans and whites, there has been little research on how the rela ... Full text Link to item Cite

A prospective study of weight gain after premenopausal hysterectomy.

Journal article J Womens Health (Larchmt) · May 2009 Featured Publication PURPOSE: Many women who have had hysterectomies have the perception that they gained weight after surgery that cannot be attributed to changes in diet or physical activity. The purpose of this analysis was to assess weight gain in premenopausal women in th ... Full text Link to item Cite

Single nucleotide polymorphisms in the TP53 region and susceptibility to invasive epithelial ovarian cancer.

Journal article Cancer Res · March 15, 2009 Featured Publication The p53 protein is critical for multiple cellular functions including cell growth and DNA repair. We assessed whether polymorphisms in the region encoding TP53 were associated with risk of invasive ovarian cancer. The study population includes a total of 5 ... Full text Link to item Cite

Epidemiology of basal-like breast cancer.

Journal article Breast Cancer Res Treat · May 2008 Featured Publication Risk factors for the newly identified "intrinsic" breast cancer subtypes (luminal A, luminal B, basal-like and human epidermal growth factor receptor 2-positive/estrogen receptor-negative) were determined in the Carolina Breast Cancer Study, a population-b ... Full text Link to item Cite

Hormonal risk factors for ovarian cancer in premenopausal and postmenopausal women.

Journal article Am J Epidemiol · May 1, 2008 Featured Publication Ovarian cancer is most frequently diagnosed in postmenopausal women; however, the strongest risk predictors, pregnancy and oral contraceptive use, occur in most women in their twenties and thirties. Relatively few studies have examined how reproductive ris ... Full text Link to item Cite

Race, breast cancer subtypes, and survival in the Carolina Breast Cancer Study.

Journal article JAMA · June 7, 2006 Featured Publication CONTEXT: Gene expression analysis has identified several breast cancer subtypes, including basal-like, human epidermal growth factor receptor-2 positive/estrogen receptor negative (HER2+/ER-), luminal A, and luminal B. OBJECTIVES: To determine population-b ... Full text Link to item Cite

Antidepressant medication use [corrected] and risk of ovarian cancer.

Journal article Obstet Gynecol · April 2005 Featured Publication OBJECTIVE: It has been hypothesized that antidepressants may enhance cancer growth. Previous studies of antidepressant use and ovarian cancer have been inconsistent and have been limited in their ability to examine the association with selective serotonin ... Full text Link to item Cite

Race, anthropometric factors, and stage at diagnosis of breast cancer.

Journal article Am J Epidemiol · February 1, 2001 Featured Publication A recent study suggested that the greater prevalence of severe obesity among African-American women explained almost one third of the observed differences between African-American and White women in stage at diagnosis of breast cancer. The objective of thi ... Full text Link to item Cite

Participation rates in a case-control study: the impact of age, race, and race of interviewer.

Journal article Ann Epidemiol · April 1999 Featured Publication PURPOSE: Despite concerns about declining participation rates in epidemiologic studies in recent years, relatively few papers have discussed obstacles to recruiting study participants or strategies for optimizing response rates. This report describes facto ... Full text Link to item Cite